@book{BlassUibel2012,
  author    = {Blaß, Hans Joachim and Uibel, Thomas},
  title     = {Spaltversagen von Holz in mehrreihigen Verbindungen : Erweiterung des Rechen-modells f{\"u}r die Rissbildung beim Eindrehen von Holzschrauben},
  publisher = {KIT Scientific Publishing},
  address   = {Karlsruhe},
  isbn      = {978-3-86644-852-0},
  pages     = {VIII, 166 S. : Ill., graph. Darst.},
  year      = {2012},
  language  = {de}
}
@article{NomdedeuWillenSchiefferetal.2012,
  author    = {Nomdedeu, Mar Monsonis and Willen, Christine and Schieffer, Andre and Arndt, Hartmut},
  title     = {Temperature-dependent ranges of coexistence in a model of a two-prey-one-predator microbial food web},
  series = {Marine Biology},
  volume    = {159},
  journal   = {Marine Biology},
  number    = {11},
  publisher = {Springer},
  address   = {Berlin},
  issn      = {1432-1793},
  doi       = {10.1007/s00227-012-1966-x},
  pages     = {2423 -- 2430},
  year      = {2012},
  abstract  = {The objective of our study was to analyze the effects of temperature on the population dynamics of a three-species food web consisting of two prey bacteria (Pedobacter sp. and Acinetobacter johnsonii) and a protozoan predator (Tetrahymena pyriformis) as model organisms. We assessed the effects of temperature on the growth rates of all three species with the objective of developing a model with four differential equations based on the experimental data. The following hypotheses were tested at a theoretical level: Firstly, temperature changes can affect the dynamic behavior of a system by temperature-dependent parameters and interactions and secondly, food web response to temperature cannot be derived from the single species temperature response. The main outcome of the study is that temperature changes affect the parameter range where coexistence is possible within all three species. This has significant consequences on our ideas regarding the evaluation of effects of global warming.},
  language  = {en}
}
@phdthesis{Schieffer2012,
  author    = {Schieffer, Andre},
  title     = {Studies on diversity and coexistence in an experimental microbial community},
  pages     = {76 Bl. : Ill.},
  year      = {2012},
  abstract  = {Biodiversity and the coexistence of species have puzzled and fascinated biologists since decades and is a hotspot in todays' natural sciences. Preserving this biodiversity is a great challenge as habitats and environments underlying tremendous changes like climate change and the loss of natural habitats, which are mainly due to anthropogenic influences. The coexistence of numerous species even in homogeneous environments is a stunning feature of natural communities and has been summarized under the term 'paradox of plankton'. Up to now, there are several mechanisms discussed, which may contribute to local and global diversity of organisms. Several interspecific trade offs have been identified maintaining the coexistence of species like their abilities regarding competition and predator avoidance, their capability to disperse in space and time, and their ability to exploit variable resources. Further, micro-evolutionary dynamics supporting the coexistence of species have been added to our knowledge, and deriving from theoretical deterministic models, non-linear dynamics which describe the temporal fluctuation of abundances of organisms. Whereas competition and predation seem to be clue structural elements within interacting organisms, the intrinsic dynamic behavior - by means of temporal changes in abundance - plays an important role regarding coexistence within a community. The present work sheds light on different factors affecting the coexistence of species using experimental microbial model systems consisting of a bacterivorous ciliate as the predator and two bacteria strains as prey organism. Additionally, another experimental setup consisting of two up to five bacteria species competing for one limiting resource was investigated. Highly controllable chemostat systems were established to exclude extrinsic disturbances. According to theoretical analyses I was able to show - experimentally and theoretically - that phenotypic plasticity of one species within a microbial one-predator-two-prey food web enlarges the range of possible coexistence of all species under different dynamic conditions, compared to a food web without phenotypic plasticity. This was accompanied by non-linear (chaotic) population dynamics within all experimental systems showing phenotypic plasticity. The experiments on the interplay of competition, predation and invasion showed that all aspects have an influence on species coexistence. Under undisturbed controlled conditions all aspects were analyzed in detail and in combination. Populations showed oscillations which were shown by quasi-chaotic attractors in phase space diagrams. Competition experiments with two up to five bacteria species competing for one limiting resource showed that all organisms were able to coexist which was mediated by species oscillations entering a regime of chaos. Besides that fact it was found, that the productivity (biomass) as well as the total cell numbers - under the same nutrition supply - increased by an increasing number of species in the experimental systems. Up to now, the occurrence of non-linear dynamics in well controlled experimental studies has been recognized several times and this phenomenon seemed to be more common in natural systems than generally assumed.},
  language  = {en}
}
@article{Alexopoulos2012,
  author    = {Alexopoulos, Spiros},
  title     = {Biogas systems: basics, biogas multifunction, principle of fermentation and hybrid application with a solar tower for the treatment of waste animal manure},
  series = {Journal of Engineering Science and Technology Review},
  volume    = {5},
  journal   = {Journal of Engineering Science and Technology Review},
  number    = {4},
  issn      = {1791-2377},
  pages     = {48 -- 55},
  year      = {2012},
  abstract  = {Two of the main environmental problems of today's society are the continuously increasing production of organic wastes as well as the increase of carbon dioxide in the atmosphere and the related green house effect. A way to solve these problems is the production of biogas. Biogas is a combustible gas consisting of methane, carbon dioxide and small amounts of other gases and trace elements. Production of biogas through anaerobic digestion of animal manure and slurries as well as of a wide range of digestible organic wastes and agricultural residues, converts these substrates into electricity and heat and offers a natural fertiliser for agriculture. The microbiological process of decomposition of organic matter, in the absence of oxygen takes place in reactors, called digesters. Biogas can be used as a fuel in a gas turbine or burner and can be used in a hybrid solar tower system offering a solution for waste treatment of agricultural and animal residues. A solar tower system consists of a heliostat field, which concentrates direct solar irradiation on an open volumetric central receiver. The receiver heats up ambient air to temperatures of around 700°C. The hot air's heat energy is transferred to a steam Rankine cycle in a heat recovery steam generator (HRSG). The steam drives a steam turbine, which in turn drives a generator for producing electricity. In order to increase the operational hours of a solar tower power plant, a heat storage system and/ or hybridization may be considered. The advantage of solar-fossil hybrid power plants, compared to solar-only systems, lies in low additional investment costs due to an adaptable solar share and reduced technical and economical risks. On sunny days the hybrid system operates in a solar-only mode with the central receiver and on cloudy days and at night with the gas turbine only. As an alternative to methane gas, environmentally neutral biogas can be used for operating the gas turbine. Hence, the hybrid system is operated to 100\% from renewable energy sources},
  language  = {en}
}
@inproceedings{StreunAlKaddoumParletal.2012,
  author    = {Streun, M. and Al-Kaddoum, R. and Parl, C. and Pietrzyk, U. and Ziemons, Karl and Waasen, S. van},
  title     = {Simulation studies of optical photons in monolithic block scintillators},
  series = {2011 IEEE Nuclear Science Symposium Conference Record (NSS/MIC)},
  booktitle = {2011 IEEE Nuclear Science Symposium Conference Record (NSS/MIC)},
  publisher = {IEEE},
  address   = {New York},
  isbn      = {978-1-4673-0120-6 (electronic ISBN)},
  doi       = {10.1109/NSSMIC.2011.6154621},
  pages     = {1380 -- 1382},
  year      = {2012},
  abstract  = {The interest in PET detectors with monolithic block scintillators is growing. In order to obtain high spatial resolutions dedicated positioning algorithms are required. But even an ideal algorithm can only deliver information which is provided by the detector. In this simulation study we investigated the light distribution on one surface of cuboid LSO scintillators of different size. Scintillators with a large aspect ratio (small footprint and large height) showed significant position information only for a minimum interaction depth of the gamma particle. The results allow a quantitative estimate for a useful aspect ratio.},
  language  = {en}
}
@inproceedings{FrotscherRaatschenStaat2012,
  author    = {Frotscher, Ralf and Raatschen, Hans-J{\"u}rgen and Staat, Manfred},
  title     = {Effectiveness of the edge-based smoothed finite element method applied to soft biological tissues},
  series = {ESMC-2012 - 8th European Solid Mechanics Conference, Graz, Austria, July 9-13, 2012},
  booktitle = {ESMC-2012 - 8th European Solid Mechanics Conference, Graz, Austria, July 9-13, 2012},
  editor    = {Holzapfel, Gerhard A.},
  publisher = {Verlag d. Technischen Universit{\"a}t Graz},
  address   = {Graz},
  isbn      = {978-3-85125-223-1},
  year      = {2012},
  language  = {en}
}
@inproceedings{DuongNguyenStaat2012,
  author    = {Duong, Minh Tuan and Nguyen, Nhu Hunyh and Staat, Manfred},
  title     = {Finite Element Implementation of a 3D Fung-type Model},
  series = {ESMC-2012 - 8th European Solid Mechanics Conference, Graz, Austria, July 9-13, 2012},
  booktitle = {ESMC-2012 - 8th European Solid Mechanics Conference, Graz, Austria, July 9-13, 2012},
  publisher = {Verlag d. Technischen Universit{\"a}t Graz},
  address   = {Graz},
  isbn      = {978-3-85125-223-1},
  year      = {2012},
  language  = {en}
}
@article{HoetterFateriGebhardt2012,
  author    = {H{\"o}tter, Jan-Steffen and Fateri, Miranda and Gebhardt, Andreas},
  title     = {Prozessoptimierung des SLM-Prozesses mit hoch-reflektiven und thermisch sehr gut leitenden Materialien durch systematische Parameterfindung und begleitende Simulationen am Beispiel von Silber},
  series = {RTejournal - Forum f{\"u}r Rapid Technologie},
  volume    = {9},
  journal   = {RTejournal - Forum f{\"u}r Rapid Technologie},
  number    = {1},
  publisher = {Fachhoschule Aachen},
  address   = {Aachen},
  issn      = {1614-0923},
  url       = {http://nbn-resolving.de/urn:nbn:de:0009-2-33639},
  pages     = {1 -- 14},
  year      = {2012},
  abstract  = {Additive Manufacturing durch Aufschmelzen von Metallpulvern hat sich auf breiter Front als Herstellverfahren, auch f{\"u}r Endprodukte, etabliert. Besonders f{\"u}r die Variante des Selective Laser Melting (SLM) sind Anwendungen in der Zahntechnik bereits weit verbreitet und der Einsatz in sensitiven Branchen wie der Luftfahrt ist in greifbare N{\"a}he ger{\"u}ckt. Deshalb werden auch vermehrt Anstrengungen unternommen, um bisher nicht verarbeitete Materialien zu qualifizieren. Dies sind vorzugsweise Nicht-Eisen- und Edelmetalle, die sowohl eine sehr hohe Reflektivit{\"a}t als auch eine sehr gute W{\"a}rmeleitf{\"a}higkeit aufweisen - beides Eigenschaften, die die Beherrschung des Laser-Schmelzprozesses erschweren und nur kleine Prozessfenster zulassen. Die Arbeitsgruppe SLM des Lehr- und Forschungsgebietes Hochleistungsverfahren der Fertigungstechnik hat sich unter der Randbedingung einer kleinen und mit geringer Laserleistung ausgestatteten SLM Maschine der Aufgabe gewidmet und am Beispiel von Silber die Parameterfelder f{\"u}r Einzelspuren und wenig komplexe Geometrien systematisch untersucht. Die Arbeiten wurden von FEM Simulationen begleitet und durch metallographische Untersuchungen verifiziert. Die Ergebnisse bilden die Grundlage zur schnellen Parameterfindung bei komplexen Geometrien und bei Ver{\"a}nderungen der Zusammensetzung, wie sie bei zuk{\"u}nftigen Legierungen zu erwarten sind. Die Ergebnisse werden exemplarisch auf unterschiedliche Geometrien angewandt und entsprechende Bauteile gezeigt.},
  language  = {de}
}
@incollection{Fabo2012,
  author    = {Fabo, Sabine},
  title     = {Einf{\"u}hrung},
  series = {Vielen Dank f{\"u}r Ihren Einkauf : Konsumkultur aus Sicht von Design, Kunst und Medien},
  booktitle = {Vielen Dank f{\"u}r Ihren Einkauf : Konsumkultur aus Sicht von Design, Kunst und Medien},
  publisher = {Transcript Verlag},
  address   = {Bielefeld},
  isbn      = {978-3-8376-2170-9},
  pages     = {9 -- 13},
  year      = {2012},
  language  = {de}
}
@incollection{Fabo2012,
  author    = {Fabo, Sabine},
  title     = {Die Kunst der Irritation und ihr Mehrwert},
  series = {Vielen Dank f{\"u}r Ihren Einkauf : Konsumkultur aus Sicht von Design, Kunst und Medien},
  booktitle = {Vielen Dank f{\"u}r Ihren Einkauf : Konsumkultur aus Sicht von Design, Kunst und Medien},
  publisher = {Transcript Verlag},
  address   = {Bielefeld},
  isbn      = {978-3-8376-2170-9},
  pages     = {112 -- 145},
  year      = {2012},
  language  = {de}
}
@incollection{Kurz2012,
  author    = {Kurz, Melanie},
  title     = {Prizing \& Pricing : Design zwischen Rang und Regal},
  series = {Vielen Dank f{\"u}r Ihren Einkauf : Konsumkultur aus Sicht von Design, Kunst und Medien},
  booktitle = {Vielen Dank f{\"u}r Ihren Einkauf : Konsumkultur aus Sicht von Design, Kunst und Medien},
  publisher = {Transcript Verlag},
  address   = {Bielefeld},
  isbn      = {978-3-8376-2170-9},
  doi       = {10.1515/transcript.9783839421703.26},
  pages     = {26 -- 39},
  year      = {2012},
  language  = {de}
}
@incollection{Jakobs2012,
  author    = {Jakobs, Helmut},
  title     = {Vorwort},
  series = {Vielen Dank f{\"u}r Ihren Einkauf : Konsumkultur aus Sicht von Design, Kunst und Medien},
  booktitle = {Vielen Dank f{\"u}r Ihren Einkauf : Konsumkultur aus Sicht von Design, Kunst und Medien},
  publisher = {Transcript Verlag},
  address   = {Bielefeld},
  isbn      = {978-3-8376-2170-9},
  pages     = {7},
  year      = {2012},
  language  = {de}
}
@article{LustfeldPithanReissel2012,
  author    = {Lustfeld, H. and Pithan, C. and Reißel, Martin},
  title     = {Metallic electrolyte composites in the framework of the brick-layer model},
  series = {Journal of the European Ceramic Society},
  volume    = {32},
  journal   = {Journal of the European Ceramic Society},
  number    = {4},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0955-2219},
  doi       = {10.1016/j.jeurceramsoc.2011.10.017},
  pages     = {859 -- 864},
  year      = {2012},
  abstract  = {It is well known that the already large dielectric constants of some electrolytes like BaTiO₃ can be enhanced further by adding metallic (e.g. Ni, Cu or Ag) nanoparticles. The enhancement can be quite large, a factor of more than 1000 is possible. The consequences for the properties will be discussed in the present paper applying a brick-layer model (BLM) for calculating dc-resistivities of thin layers and a modified one (PBLM) that includes percolation for calculating dielectric properties of these materials. The PBLM results in an at least qualitative description and understanding of the physical phenomena: This model gives an explanation for the steep increase of the dielectric constant below the percolation threshold and why this increase is connected to a dramatic decrease of the breakdown voltage as well as the ability of storing electrical energy. We conclude that metallic electrolyte composites like BaTiO₃ are not appropriate for energy storage.},
  language  = {en}
}
@article{KernSchelthoffMathieu2012,
  author    = {Kern, Alexander and Schelthoff, Christof and Mathieu, Moritz},
  title     = {Detaillierte Berechnung der Einfangwirksamkeiten von Fangeinrichtungen},
  series = {Elektro-Praktiker},
  volume    = {66},
  journal   = {Elektro-Praktiker},
  number    = {4},
  publisher = {Huss Medien},
  address   = {Berlin},
  issn      = {0013-5569},
  pages     = {6 Seiten},
  year      = {2012},
  abstract  = {Im Beitrag wird zun{\"a}chst das Verfahren eines dynamischen elektro-geometrischen Modells vorgestellt. Dieses arbeitet im Gegensatz zum klassischen Blitzkugel-Verfahren nicht mit konstanten Radien; vielmehr wird der Radius der Blitzkugel variiert. Dabei werden ausschließlich vorhandene und in internationalen Normen anerkannte Ergebnisse, blitzphysikalische Grundlagen und Untersuchungen verwendet, und auf deren Grundlage ein numerisches Verfahren erarbeitet. Mit dem dynamischen elektro-geometrischen Modell werden dann einige Beispiele des Schutzes mit Fangstangen, die gem{\"a}ß dem klassischen Blitzkugel-Verfahren nach DIN EN 62305-3 f{\"u}r die Schutzklassen I - II - III - IV geplant sind, untersucht. Es wird gezeigt, dass die Einfangwirksamkeiten wesentlich h{\"o}her sind als in der Normenreihe DIN EN 62305 selbst angegeben. Grund daf{\"u}r ist die Tatsache, dass das Blitzkugel-Verfahren sehr konservativ aufgebaut ist und dem Planer von Blitzschutzsystemen nur die m{\"o}glichen Stellen f{\"u}r einen Einschlag aufzeigt, ohne eine Bewertung der Einschlagsh{\"a}ufigkeit zu liefern. Andererseits bedeutet dies jedoch, dass man mit dem klassischen Blitzkugel-Verfahren stets auf der „sicheren Seite" liegt.},
  language  = {de}
}
@inproceedings{ReisertGeisslerFloerkeetal.2012,
  author    = {Reisert, Steffen and Geissler, H. and Fl{\"o}rke, R. and Weiler, C. and Wagner, P. and Sch{\"o}ning, Michael Josef},
  title     = {Characterisation of aseptic sterilisation processes using an electronic nose},
  series = {Nanoscale Science and Technology (NS\&T´12) : Proceedings Book Humboldt Kolleg ; Tunisia, 17-19 March, 2012},
  booktitle = {Nanoscale Science and Technology (NS\&T´12) : Proceedings Book Humboldt Kolleg ; Tunisia, 17-19 March, 2012},
  editor    = {Abdelghani, Adnane and Sch{\"o}ning, Michael Josef},
  pages     = {45 -- 45},
  year      = {2012},
  language  = {en}
}
@inproceedings{SchusserLeinhosPoghossianetal.2012,
  author    = {Schusser, Sebastian and Leinhos, Marcel and Poghossian, Arshak and Wagner, Patrick and Sch{\"o}ning, Michael Josef},
  title     = {Biopolymer-degradation monitoring by chip-­based impedance spectroscopy technique},
  series = {Nanoscale Science and Technology (NS\&T´12) : Proceedings Book Humboldt Kolleg ; Tunisia, 17-19 March, 2012},
  booktitle = {Nanoscale Science and Technology (NS\&T´12) : Proceedings Book Humboldt Kolleg ; Tunisia, 17-19 March, 2012},
  editor    = {Abdelghani, Adnane and Sch{\"o}ning, Michael Josef},
  pages     = {47 -- 47},
  year      = {2012},
  language  = {en}
}
@article{AbouzarPoghossianCherstvyetal.2012,
  author    = {Abouzar, Maryam H. and Poghossian, Arshak and Cherstvy, Andrey G. and Pedraza, Angela M. and Ingebrandt, Sven and Sch{\"o}ning, Michael Josef},
  title     = {Label-free electrical detection of DNA by means of field-effect nanoplate capacitors: Experiments and modeling},
  series = {Physica Status Solidi (a)},
  volume    = {209},
  journal   = {Physica Status Solidi (a)},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {1862-6319},
  doi       = {10.1002/pssa.201100710},
  pages     = {925 -- 934},
  year      = {2012},
  abstract  = {Label-free electrical detection of consecutive deoxyribonucleic acid (DNA) hybridization/denaturation by means of an array of individually addressable field-effect-based nanoplate silicon-on-insulator (SOI) capacitors modified with gold nanoparticles (Au-NP) is investigated. The proposed device detects charge changes on Au-NP/DNA hybrids induced by the hybridization or denaturation event. DNA hybridization was performed in a high ionic-strength solution to provide a high hybridization efficiency. On the other hand, to reduce the screening of the DNA charge by counter ions and to achieve a high sensitivity, the sensor signal induced by the hybridization and denaturation events was measured in a low ionic-strength solution. High sensor signals of about 120, 90, and 80 mV were registered after the DNA hybridization, denaturation, and re-hybridization events, respectively. Fluorescence microscopy has been applied as reference method to verify the DNA immobilization, hybridization, and denaturation processes. An electrostatic charge-plane model for potential changes at the gate surface of a nanoplate field-effect sensor induced by the DNA hybridization has been developed taking into account both the Debye length and the distance of the DNA charge from the gate surface.},
  language  = {en}
}
@article{SchubaHoefkenSchaefer2012,
  author    = {Schuba, Marko and H{\"o}fken, H. and Schaefer, T.},
  title     = {Smartphone Forensik},
  series = {Hakin9 : Practical Protection (2012)},
  journal   = {Hakin9 : Practical Protection (2012)},
  publisher = {-},
  isbn      = {1733-7186},
  pages     = {10 -- 20},
  year      = {2012},
  language  = {de}
}
@inproceedings{YoshinobuMiyamotoWagneretal.2012,
  author    = {Yoshinobu, Tatsuo and Miyamoto, Ko-Ichiro and Wagner, Torsten and Sch{\"o}ning, Michael Josef},
  title     = {Miniaturized and high-speed chemical imaging systems},
  series = {Nano-Biomedical Engineering 2012. Proceedings of the Tohoku University Global Centre of Excellence Programme, Sakura Hall, Tohoku University, Sendai Japan, 5 - 6 March 2012},
  booktitle = {Nano-Biomedical Engineering 2012. Proceedings of the Tohoku University Global Centre of Excellence Programme, Sakura Hall, Tohoku University, Sendai Japan, 5 - 6 March 2012},
  editor    = {Yamaguchi, Takami},
  publisher = {World Scientific},
  address   = {Singapur},
  doi       = {10.1142/9781848169067_0045},
  pages     = {386 -- 395},
  year      = {2012},
  language  = {en}
}
@article{ChwallekEngelenOswaldetal.2012,
  author    = {Chwallek, Constanze and Engelen, Andreas and Oswald, Monika and Brettel, Malte},
  title     = {Die Wir­kung des F{\"u}h­rungs­ver­hal­tens des Top-Ma­nage­ments auf die un­ter­neh­me­ri­sche Ori­en­tie­rung - ein 5-L{\"a}n­der-Ver­gleich},
  series = {Zfbf : Schmalenbachs Zeitschrift f{\"u}r betriebswirtschaftliche Forschung},
  journal   = {Zfbf : Schmalenbachs Zeitschrift f{\"u}r betriebswirtschaftliche Forschung},
  number    = {2},
  publisher = {Springer Fachmedien},
  address   = {Wiesbaden},
  issn      = {0341-2687},
  pages     = {138 -- 165},
  year      = {2012},
  language  = {de}
}
@article{BackesAdamGottschaldetal.2012,
  author    = {Backes, Klaus and Adam, Mario and Gottschald, Beng Jonas and Faber, Christian and Henneb{\"o}hl, Friedrich-Gregor and Lanz, Marco and Anthrakidis, Anette},
  title     = {KWKK-Anlagen im Feldtest. Optimaler Betrieb durch Verbesserungen bei Regelung und Hydraulik},
  series = {Die K{\"a}lte- und Klimatechnik},
  journal   = {Die K{\"a}lte- und Klimatechnik},
  number    = {2},
  publisher = {Gentner},
  address   = {Stuttgart},
  issn      = {0343-2246},
  year      = {2012},
  language  = {de}
}
@article{LeursMezoOehlschlaegeretal.2012,
  author    = {Leurs, Ulrike and Mezo, Gabor and {\"O}hlschl{\"a}ger, Peter and Orban, Erika and Marquard, Andrea and Manea, Marilena},
  title     = {Design, synthesis, in vitro stability and cytostatic effect of multifunctional anticancer drug-bioconjugates containing GnRH-III as a targeting moiety},
  series = {Peptide Science},
  volume    = {98},
  journal   = {Peptide Science},
  number    = {1},
  publisher = {Wiley},
  address   = {New York, NY},
  issn      = {1097-0282},
  doi       = {10.1002/bip.21640},
  pages     = {1 -- 10},
  year      = {2012},
  abstract  = {Bioconjugates containing the GnRH-III hormone decapeptide as a targeting moiety are able to deliver chemotherapeutic agents specifically to cancer cells expressing GnRH receptors, thereby increasing their local efficacy while limiting the peripheral toxicity. However, the number of GnRH receptors on cancer cells is limited and they desensitize under continuous hormone treatment. A possible approach to increase the receptor mediated tumor targeting and consequently the cytostatic effect of the bioconjugates would be the attachment of more than one chemotherapeutic agent to one GnRH-III molecule. Here we report on the design, synthesis and biochemical characterization of multifunctional bioconjugates containing GnRH-III as a targeting moiety and daunorubicin as a chemotherapeutic agent. Two different drug design approaches were pursued. The first one was based on the bifunctional [4Lys]-GnRH-III (Glp-His-Trp-Lys-His-Asp-Trp-Lys-Pro-Gly-NH2) containing two lysine residues in positions 4 and 8, whose ϵ-amino groups were used for the coupling of daunorubicin. In the second drug design, the native GnRH-III (Glp-His-Trp-Ser-His-Asp-Trp-Lys-Pro-Gly-NH2) was used as a scaffold; an additional lysine residue was coupled to the ϵ-amino group of 8Lys in order to generate two free amino groups available for conjugation of daunorubicin. The in vitro stability/degradation of all synthesized compounds was investigated in human serum, as well as in the presence of rat liver lysosomal homogenate. Their cellular uptake was determined on human breast cancer cells and the cytostatic effect was evaluated on human breast, colon and prostate cancer cell lines. Compared with a monofunctional compound, both drug design approaches resulted in multifunctional bioconjugates with increased cytostatic effect.},
  language  = {en}
}
@article{GrinsvenBonStrauvenetal.2012,
  author    = {Grinsven, Bart van and Bon, Natalie vanden and Strauven, Hannelore and Grieten, Lars and Murib, Mohammed and Jim{\´e}nez Monroy, Kathia L. and Janssens, Stoffel D. and Haenen, Ken and Sch{\"o}ning, Michael Josef and Vermeeren, Veronique and Ameloot, Marcel and Michiels, Luc and Thoelen, Ronald and Ceuninck, Ward de and Wagner, Patrick},
  title     = {Heat-Transfer Resistance at Solid-Liquid Interfaces: A Tool for The Detection of Single Nucleotide Polymorphisms in DNA.},
  series = {ACS Nano},
  volume    = {6},
  journal   = {ACS Nano},
  number    = {3},
  publisher = {ACS Publications},
  address   = {Washington, DC},
  issn      = {1936-086X},
  doi       = {10.1021/nn300147e},
  pages     = {2712 -- 2721},
  year      = {2012},
  abstract  = {In this article, we report on the heat-transfer resistance at interfaces as a novel, denaturation-based method to detect single-nucleotide polymorphisms in DNA. We observed that a molecular brush of double-stranded DNA grafted onto synthetic diamond surfaces does not notably affect the heat-transfer resistance at the solid-to-liquid interface. In contrast to this, molecular brushes of single-stranded DNA cause, surprisingly, a substantially higher heat-transfer resistance and behave like a thermally insulating layer. This effect can be utilized to identify ds-DNA melting temperatures via the switching from low- to high heat-transfer resistance. The melting temperatures identified with this method for different DNA duplexes (29 base pairs without and with built-in mutations) correlate nicely with data calculated by modeling. The method is fast, label-free (without the need for fluorescent or radioactive markers), allows for repetitive measurements, and can also be extended toward array formats. Reference measurements by confocal fluorescence microscopy and impedance spectroscopy confirm that the switching of heat-transfer resistance upon denaturation is indeed related to the thermal on-chip denaturation of DNA.},
  language  = {en}
}
@inproceedings{FredebeulKreinSteingroever2012,
  author    = {Fredebeul-Krein, Markus and Steingr{\"o}ver, Markus},
  title     = {Wholesale Broadband Access to IPTV in an NGA environment : how to deal with it from a regulatory perspective?},
  pages     = {1 -- 16},
  year      = {2012},
  language  = {en}
}
@article{TimmeGuennewig2012,
  author    = {Timme, Michael and G{\"u}nnewig, Sebastian},
  title     = {Betriebskostenabrechnung - Die Pflicht des Vermieters zur Beachtung des Wirtschaftlichkeitsgebots},
  series = {Der Miet-Rechts-Berater : MietRB ; Miete, Immobilien, Wohnungseigentum},
  journal   = {Der Miet-Rechts-Berater : MietRB ; Miete, Immobilien, Wohnungseigentum},
  number    = {3},
  publisher = {Verlag Dr. Otto Schmidt},
  address   = {K{\"o}ln},
  issn      = {1612-040X},
  pages     = {83 -- 88},
  year      = {2012},
  abstract  = {Mit seiner aktuellen Entscheidung (BGH v. 6.11.2011 - VIII ZR 340/10, MDR 2011, 1095 = MietRB MDR 2011, 337) hat der BGH die Darlegungs- und Beweislast f{\"u}r einen Verstoß gegen das Gebot der Wirtschaftlichkeit bei der Abrechnung von Betriebskosten konkretisiert. Der Beitrag erl{\"a}utert anhand der Hintergr{\"u}nde des Gebotes der Wirtschaftlichkeit die Konsequenzen f{\"u}r die Praxis.},
  language  = {de}
}
@article{SchneiderSchneider2012,
  author    = {Schneider, Bettina and Schneider, Wilhelm},
  title     = {Externes Rechnungswesen nach BilMoG: Grundelemente und Aufbau},
  series = {Das Wirtschaftsstudium : wisu ; Zeitschrift f{\"u}r Ausbildung, Examen, Berufseinstieg und Fortbildung},
  volume    = {41},
  journal   = {Das Wirtschaftsstudium : wisu ; Zeitschrift f{\"u}r Ausbildung, Examen, Berufseinstieg und Fortbildung},
  number    = {3},
  publisher = {Lange},
  address   = {D{\"u}sseldorf},
  issn      = {0340-3084},
  pages     = {332 -- 337},
  year      = {2012},
  language  = {de}
}
@book{HoepnerSchminke2012,
  author    = {Hoepner, Gert and Schminke, Lutz H.},
  title     = {Dialog-Marketing und E-Commerce : ein anwendungsorientiertes und konzeptionelles Kompendium f{\"u}r Praxis und Ausbildung},
  publisher = {Uni-ed. GmbH},
  address   = {Berlin},
  isbn      = {978-3-942171-23-6},
  pages     = {XXXI, 339 S.: graph. Darst.},
  year      = {2012},
  language  = {de}
}
@inproceedings{PoghossianAbouzarSchoening2012,
  author    = {Poghossian, Arshak and Abouzar, Maryam H. and Sch{\"o}ning, Michael Josef},
  title     = {(Bio-­)chemical sensor array based on nanoplate SOI capacitors},
  series = {Nanoscale Science and Technology (NS\&T´12) : Proceedings Book Humboldt Kolleg ; Tunisia, 17-19 March, 2012},
  booktitle = {Nanoscale Science and Technology (NS\&T´12) : Proceedings Book Humboldt Kolleg ; Tunisia, 17-19 March, 2012},
  editor    = {Abdelghani, Adnane and Sch{\"o}ning, Michael Josef},
  pages     = {31 -- 31},
  year      = {2012},
  language  = {en}
}
@inproceedings{BohrnStuetzFleischeretal.2012,
  author    = {Bohrn, U. and St{\"u}tz, E. and Fleischer, M. and Sch{\"o}ning, Michael Josef and Wagner, P.},
  title     = {Towards a paradigm change - mammalian cells as sensitive biosensor layers for the detection of unexpected toxic substances in air},
  series = {Nanoscale Science and Technology (NS\&T´12) : Proceedings Book Humboldt Kolleg ; Tunisia, 17-19 March, 2012},
  booktitle = {Nanoscale Science and Technology (NS\&T´12) : Proceedings Book Humboldt Kolleg ; Tunisia, 17-19 March, 2012},
  editor    = {Abdelghani, Adnane and Sch{\"o}ning, Michael Josef},
  pages     = {44 -- 44},
  year      = {2012},
  language  = {en}
}
@article{BaeckerRaueSchusseretal.2012,
  author    = {B{\"a}cker, Matthias and Raue, Markus and Schusser, Sebastian and Jeitner, C. and Breuer, L. and Wagner, P. and Poghossian, Arshak and F{\"o}rster, Arnold and Mang, Thomas and Sch{\"o}ning, Michael Josef},
  title     = {Microfluidic chip with integrated microvalves based on temperature- and pH-responsive hydrogel thin films},
  series = {Physica Status Solidi (a)},
  volume    = {209},
  journal   = {Physica Status Solidi (a)},
  number    = {5},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {1862-6319},
  doi       = {10.1002/pssa.201100763},
  pages     = {839 -- 845},
  year      = {2012},
  abstract  = {Two types of microvalves based on temperature-responsive poly(N-isopropylacrylamide) (PNIPAAm) and pH-responsive poly(sodium acrylate) (PSA) hydrogel films have been developed and tested. The PNIPAAm and PSA hydrogel films were prepared by means of in situ photopolymerization directly inside the fluidic channel of a microfluidic chip fabricated by combining Si and SU-8 technologies. The swelling/shrinking properties and height changes of the PNIPAAm and PSA films inside the fluidic channel were studied at temperatures of deionized water from 14 to 36 °C and different pH values (pH 3-12) of Titrisol buffer, respectively. Additionally, in separate experiments, the lower critical solution temperature (LCST) of the PNIPAAm hydrogel was investigated by means of a differential scanning calorimetry (DSC) and a surface plasmon resonance (SPR) method. Mass-flow measurements have shown the feasibility of the prepared hydrogel films to work as an on-chip integrated temperature- or pH-responsive microvalve capable to switch the flow channel on/off.},
  language  = {en}
}
@inproceedings{SchusserVaessenSchoening2012,
  author    = {Schusser, Sebastian and Vaeßen, Christiane and Sch{\"o}ning, Michael Josef},
  title     = {5. Graduiertentagung der FH Aachen 15. November 2012},
  url       = {http://nbn-resolving.de/urn:nbn:de:hbz:a96-opus-50425},
  pages     = {52},
  year      = {2012},
  abstract  = {Tagungsband der 5. Graduiertentagung der FH Aachen am 15. November 2012},
  language  = {de}
}
@article{OlaruKowalskiSethietal.2012,
  author    = {Olaru, Alexandra Maria and Kowalski, Julia and Sethi, Vaishali and Bl{\"u}mich, Bernhard},
  title     = {Exchange relaxometry of flow at small P{\´e}clet numbers in a glass bead pack},
  series = {Journal of Magnetic Resonance (JMR)},
  volume    = {220},
  journal   = {Journal of Magnetic Resonance (JMR)},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1096-0856},
  doi       = {10.1016/j.jmr.2012.04.015},
  pages     = {32 -- 44},
  year      = {2012},
  abstract  = {In this paper we consider low P{\´e}clet number flow in bead packs. A series of relaxation exchange experiments has been conducted and evaluated by ILT analysis. In the resulting correlation maps, we observed a collapse of the signal and a translation towards smaller relaxation times with increasing flow rates, as well as a signal tilt with respect to the diagonal. In the discussion of the phenomena we present a mathematical theory for relaxation exchange experiments that considers both diffusive and advective transport. We perform simulations based on this theory and discuss them with respect to the conducted experiments.},
  language  = {en}
}
@article{FischerKowalskiPudasaini2012,
  author    = {Fischer, Jan-Thomas and Kowalski, Julia and Pudasaini, Shiva P.},
  title     = {Topographic curvature effects in applied avalanche modelling},
  series = {Cold Regions Science and Technology},
  volume    = {74-75},
  journal   = {Cold Regions Science and Technology},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1872-7441},
  doi       = {10.1016/j.coldregions.2012.01.005},
  pages     = {21 -- 30},
  year      = {2012},
  abstract  = {This paper describes the implementation of topographic curvature effects within the RApid Mass MovementS (RAMMS) snow avalanche simulation toolbox. RAMMS is based on a model similar to shallow water equations with a Coulomb friction relation and the velocity dependent Voellmy drag. It is used for snow avalanche risk assessment in Switzerland. The snow avalanche simulation relies on back calculation of observed avalanches. The calibration of the friction parameters depends on characteristics of the avalanche track. The topographic curvature terms are not yet included in the above mentioned classical model. Here, we fundamentally improve this model by mathematically and physically including the topographic curvature effects. By decomposing the velocity dependent friction into a topography dependent term that accounts for a curvature enhancement in the Coulomb friction, and a topography independent contribution similar to the classical Voellmy drag, we construct a general curvature dependent frictional resistance, and thus propose new extended model equations. With three site-specific examples, we compare the apparent frictional resistance of the new approach, which includes topographic curvature effects, to the classical one. Our simulation results demonstrate substantial effects of the curvature on the flow dynamics e.g., the dynamic pressure distribution along the slope. The comparison of resistance coefficients between the two models demonstrates that the physically based extension presents an improvement to the classical approach. Furthermore a practical example highlights its influence on the pressure outline in the run out zone of the avalanche. Snow avalanche dynamics modeling natural terrain curvature centrifugal force friction coefficients.},
  language  = {en}
}
@article{PieperKlein2012,
  author    = {Pieper, Martin and Klein, Peter},
  title     = {Application of simple, periodic homogenization techniques to non-linear heat conduction problems in non-periodic, porous media},
  series = {Heat mass transfer},
  volume    = {48},
  journal   = {Heat mass transfer},
  number    = {2},
  publisher = {Springer},
  address   = {Berlin},
  issn      = {0947-7411},
  doi       = {10.1007/s00231-011-0879-4},
  pages     = {291 -- 300},
  year      = {2012},
  abstract  = {Often, detailed simulations of heat conduction in complicated, porous media have large runtimes. Then homogenization is a powerful tool to speed up the calculations by preserving accurate solutions at the same time. Unfortunately real structures are generally non-periodic, which requires unpractical, complicated homogenization techniques. We demonstrate in this paper, that the application of simple, periodic techniques to realistic media, that are just close to periodic, gives accurate, approximative solutions. In order to obtain effective parameters for the homogenized heat equation, we have to solve a so called "cell problem". In contrast to periodic structures it is not trivial to determine a suitable unit cell, which represents a non-periodic media. To overcome this problem, we give a rule of thumb on how to choose a good cell. Finally we demonstrate the efficiency of our method for virtually generated foams as well as real foams and compare these results to periodic structures.},
  language  = {en}
}
@article{FateriHoetterGebhardt2012,
  author    = {Fateri, Miranda and H{\"o}tter, Jan-Steffen and Gebhardt, Andreas},
  title     = {Experimental and Theoretical Investigation of Buckling Deformation of Fabricated Objects by Selective Laser Melting},
  series = {Physics Procedia},
  volume    = {39},
  journal   = {Physics Procedia},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1875-3892},
  doi       = {10.1016/j.phpro.2012.10.062},
  pages     = {464 -- 470},
  year      = {2012},
  abstract  = {Although Selective Laser Melting (SLM) process is an innovative manufacturing method, there are challenges such as inferior mechanical properties of fabricated objects. Regarding this, buckling deformation which is caused by thermal stress is one of the undesired mechanical properties which must be alleviated. As buckling deformation is more observable in hard to process materials, silver is selected to be studied theoretically and experimentally for this paper. Different scanning strategies are utilized and a Finite Element Method (FEM) is applied to calculate the temperature gradient in order to determine its effect on the buckling deformation of the objects from experiments.},
  language  = {en}
}
@article{HasanKeilStaatetal.2012,
  author    = {Hasan, Istabrak and Keil, Ludger and Staat, Manfred and Wahl, Gerhard and Bourauel, Christoph},
  title     = {Determination of the frictional coefficient of the implant-antler interface : experimental approach},
  series = {Biomedical Engineering / Biomedizinische Technik},
  volume    = {57},
  journal   = {Biomedical Engineering / Biomedizinische Technik},
  number    = {5},
  publisher = {De Gruyter},
  address   = {Berlin},
  issn      = {1862-278X},
  pages     = {359 -- 363},
  year      = {2012},
  abstract  = {The similar bone structure of reindeer antler to human bone permits studying the osseointegration of dental implants in the jawbone. As the friction is one of the major factors that have a significant influence on the initial stability of immediately loaded dental implants, it is essential to define the frictional coefficient of the implant-antler interface. In this study, the kinetic frictional forces at the implant-antler interface were measured experimentally using an optomechanical setup and a stepping motor controller under different axial loads and sliding velocities. The corresponding mean values of the static and kinetic frictional coefficients were within the range of 0.5-0.7 and 0.3-0.5, respectively. An increase in the frictional forces with increasing applied axial loads was registered. The measurements showed an evidence of a decrease in the magnitude of the frictional coefficient with increasing sliding velocity. The results of this study provide a considerable assessment to clarify the suitable frictional coefficient to be used in the finite element contact analysis of antler specimens.},
  language  = {en}
}
@book{WosnitzaHilgers2012,
  author    = {Wosnitza, Franz and Hilgers, Hans Gerd},
  title     = {Energieeffizienz und Energiemanagement : ein {\"U}berblick heutiger M{\"o}glichkeiten und Notwendigkeiten},
  publisher = {Springer Spektrum},
  address   = {Wiesbaden},
  isbn      = {978-3-8348-1941-3},
  pages     = {XVII, 548 S. : Ill., graph. Darst.},
  year      = {2012},
  language  = {en}
}
@book{JanserHavermann2012,
  author    = {Janser, Frank and Havermann, Marc},
  title     = {Inkompressible Str{\"o}mungen},
  publisher = {Mainz},
  address   = {Aachen},
  isbn      = {978-3-86130-446-3},
  pages     = {189 S. : Ill., graph. Darst.},
  year      = {2012},
  language  = {en}
}
@incollection{Fabo2012,
  author    = {Fabo, Sabine},
  title     = {Gef{\"a}hrliche Liebschaften : Kunst zwischen Widerstand und Umarmung},
  series = {Interventionen : Grenz{\"u}berschreitungen in {\"A}sthetik, Politik und {\"O}konomie},
  booktitle = {Interventionen : Grenz{\"u}berschreitungen in {\"A}sthetik, Politik und {\"O}konomie},
  editor    = {Hartmann, Doreen},
  publisher = {Fink},
  address   = {M{\"u}nchen},
  isbn      = {978-3-7705-5283-2},
  pages     = {173 -- 189},
  year      = {2012},
  language  = {de}
}
@inproceedings{SchoppNachtrodtHeuermannetal.2012,
  author    = {Schopp, Christoph and Nachtrodt, Frederik and Heuermann, Holger and Scherer, Ulrich W. and Mostacci, Domiziano and Finger, Torsten and Tietsch, Wolfgang},
  title     = {A novel 2.45 GHz/200 W Microwave Plasma Jet for High Temperature Applications above 3600 K},
  series = {Journal of Physics : Conference Series},
  volume    = {406},
  booktitle = {Journal of Physics : Conference Series},
  number    = {012029},
  issn      = {1742-6596},
  pages     = {5},
  year      = {2012},
  language  = {en}
}
@inproceedings{NixFrotscherStaat2012,
  author    = {Nix, Yvonne and Frotscher, Ralf and Staat, Manfred},
  title     = {Implementation of the edge-based smoothed extended finite element method},
  series = {Proceedings 6th European Congress on Computational Methods in Applied Sciences and Engineering (ECCOMAS 2012) Vienna, Austria, September 10-14, 2012},
  booktitle = {Proceedings 6th European Congress on Computational Methods in Applied Sciences and Engineering (ECCOMAS 2012) Vienna, Austria, September 10-14, 2012},
  editor    = {Eberhardsteiner, J.},
  year      = {2012},
  language  = {en}
}
@article{VerbanellaFabo2012,
  author    = {Verbanella, Stresa and Fabo, Sabine},
  title     = {Mit Pinsel und Farbe hacken : Interview mit Sabine Fabo},
  series = {Remotewords.net},
  journal   = {Remotewords.net},
  year      = {2012},
  abstract  = {Remotewords makes its mark on the picturesque "Bar Verbanella", located in Stresa near Isola Bella on Lago Maggiore. The words CUM GRANO SALIS (with a grain of salt) by Sabine Fabo, art theorist on media contexts, were applied to its roof in collaboration with the German-Italian art organization "Lo spirito del Lago".},
  language  = {de}
}
@article{Jochim2012,
  author    = {Jochim, Haldor E.},
  title     = {Die Ostheidebahn - eine Alternative zur Y-Trasse},
  series = {ETR - Eisenbahntechnische Rundschau},
  volume    = {61},
  journal   = {ETR - Eisenbahntechnische Rundschau},
  number    = {11},
  publisher = {DVV Media Group},
  address   = {Hamburg},
  issn      = {0013-2845},
  pages     = {34 -- 37},
  year      = {2012},
  language  = {de}
}
@misc{BaumgartnerWunderlichJaunichetal.2012,
  author    = {Baumgartner, Thomas and Wunderlich, Florian and Jaunich, Arthur and Sato, Tomoo and Bundy, Georg and Grießmann, Nadine and Kowalski, Julia and Burghardt, Stefan and Hanebrink, J{\"o}rg},
  title     = {Lighting the way: Perspectives on the global lighting market},
  edition   = {2nd ed.},
  address   = {McKinsey},
  pages     = {58},
  year      = {2012},
  language  = {en}
}
@inproceedings{FrotscherRaatschenStaat2012,
  author    = {Frotscher, Ralf and Raatschen, Hans-J{\"u}rgen and Staat, Manfred},
  title     = {Application of an edge-based smoothed finite element method on geometrically non-linear plates of non-linear material},
  series = {Proceedings European Congress on Computational Methods in Applied Sciences and Engineering (ECCOMAS 2012)},
  booktitle = {Proceedings European Congress on Computational Methods in Applied Sciences and Engineering (ECCOMAS 2012)},
  editor    = {Eberhardsteiner, J.},
  year      = {2012},
  language  = {en}
}
@inproceedings{DuongNguyenStaat2012,
  author    = {Duong, Minh Tuan and Nguyen, Nhu Huynh and Staat, Manfred},
  title     = {Numerical stability enhancement of modeling hyperelastic materials},
  series = {Proceedings European Congress on Computational Methods in Applied Sciences and Engineering (ECCOMAS 2012)},
  booktitle = {Proceedings European Congress on Computational Methods in Applied Sciences and Engineering (ECCOMAS 2012)},
  editor    = {Eberhardsteiner, J.},
  year      = {2012},
  language  = {en}
}
@inproceedings{TranStaat2012,
  author    = {Tran, Thanh Ngoc and Staat, Manfred},
  title     = {A primal-dual shakedown analysis of 3D structures using the face-based smoothed finite element method},
  series = {Proceedings European Congress on Computational Methods in Applied Sciences and Engineering (ECCOMAS 2012)},
  booktitle = {Proceedings European Congress on Computational Methods in Applied Sciences and Engineering (ECCOMAS 2012)},
  editor    = {Eberhardsteiner, J.},
  year      = {2012},
  language  = {en}
}
@inproceedings{PhamNguyenStaat2012,
  author    = {Pham, Phu Tinh and Nguyen, Thanh Ngoc and Staat, Manfred},
  title     = {FEM based shakedown analysis of hardening structures},
  series = {Proceedings International Conference on Advances in Computational Mechanics (ACOME)},
  booktitle = {Proceedings International Conference on Advances in Computational Mechanics (ACOME)},
  pages     = {870 -- 882},
  year      = {2012},
  language  = {en}
}
@inproceedings{Staat2012,
  author    = {Staat, Manfred},
  title     = {Limit and shakedown analysis under uncertainty},
  series = {Proceedings International Conference on Advances in Computational Mechanics (ACOME)},
  booktitle = {Proceedings International Conference on Advances in Computational Mechanics (ACOME)},
  pages     = {837 -- 861},
  year      = {2012},
  language  = {de}
}
@inproceedings{FunkeBoernerKeinzetal.2012,
  author    = {Funke, Harald and B{\"o}rner, Sebastian and Keinz, Jan and Kusterer, K. and Kroninger, D. and Kitajima, J. and Kazari, M. and Horikama, A.},
  title     = {Numerical and experimental characterization of low NOx Micromix combustion principle for industrial hydrogen gas turbine applications},
  series = {Proceedings of ASME Turbo Expo 2012},
  booktitle = {Proceedings of ASME Turbo Expo 2012},
  pages     = {11},
  year      = {2012},
  language  = {en}
}