@article{HeinkeKnickerAlbracht2021,
  author    = {Heinke, Lars N. and Knicker, Axel J. and Albracht, Kirsten},
  title     = {Test-retest reliability of the internal shoulder rotator muscles' stretch reflex in healthy men},
  series = {Journal of Electromyography and Kinesiology},
  volume    = {62},
  journal   = {Journal of Electromyography and Kinesiology},
  number    = {Article 102611},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1050-6411},
  doi       = {10.1016/j.jelekin.2021.102611},
  year      = {2021},
  abstract  = {Until now the reproducibility of the short latency stretch reflex of the internal rotator muscles of the glenohumeral joint has not been identified. Twenty-three healthy male participants performed three sets of external shoulder rotation stretches with various pre-activation levels on two different dates of measurement to assess test-retest reliability. All stretches were applied with a dynamometer acceleration of 104°/s2 and a velocity of 150°/s. Electromyographical response was measured via surface EMG. Reflex latencies showed a pre-activation effect (ƞ2 = 0,355). ICC ranged from 0,735 to 0,909 indicating an overall "good" relative reliability. SRD 95\% lay between ±7,0 to ±12,3 ms.. The reflex gain showed overall poor test-retest reproducibility. The chosen methodological approach presented a suitable test protocol for shoulder muscles stretch reflex latency evaluation. A proof-of-concept study to validate the presented methodical approach in shoulder involvement including subjects with clinically relevant conditions is recommended.},
  language  = {en}
}
@book{DiktaScheer2021,
  author    = {Dikta, Gerhard and Scheer, Marsel},
  title     = {Bootstrap Methods: With Applications in R},
  publisher = {Springer},
  address   = {Cham},
  isbn      = {978-3-030-73480-0},
  doi       = {10.1007/978-3-030-73480-0},
  pages     = {XVI, 256 Seiten},
  year      = {2021},
  abstract  = {This book provides a compact introduction to the bootstrap method. In addition to classical results on point estimation and test theory, multivariate linear regression models and generalized linear models are covered in detail. Special attention is given to the use of bootstrap procedures to perform goodness-of-fit tests to validate model or distributional assumptions. In some cases, new methods are presented here for the first time. The text is motivated by practical examples and the implementations of the corresponding algorithms are always given directly in R in a comprehensible form. Overall, R is given great importance throughout. Each chapter includes a section of exercises and, for the more mathematically inclined readers, concludes with rigorous proofs. The intended audience is graduate students who already have a prior knowledge of probability theory and mathematical statistics.},
  language  = {en}
}
@inproceedings{HueningWacheMagiera2021,
  author    = {H{\"u}ning, Felix and Wache, Franz-Josef and Magiera, David},
  title     = {Redundant bus systems using dual-mode radio},
  series = {Proceedings of Sixth International Congress on Information and Communication Technology},
  booktitle = {Proceedings of Sixth International Congress on Information and Communication Technology},
  publisher = {Springer},
  address   = {Singapore},
  isbn      = {978-981-16-2379-0},
  doi       = {10.1007/978-981-16-2380-6_73},
  pages     = {835 -- 842},
  year      = {2021},
  abstract  = {Communication via serial bus systems, like CAN, plays an important role for all kinds of embedded electronic and mechatronic systems. To cope up with the requirements for functional safety of safety-critical applications, there is a need to enhance the safety features of the communication systems. One measure to achieve a more robust communication is to add redundant data transmission path to the applications. In general, the communication of real-time embedded systems like automotive applications is tethered, and the redundant data transmission lines are also tethered, increasing the size of the wiring harness and the weight of the system. A radio link is preferred as a redundant transmission line as it uses a complementary transmission medium compared to the wired solution and in addition reduces wiring harness size and weight. Standard wireless links like Wi-Fi or Bluetooth cannot meet the requirements for real-time capability with regard to bus communication. Using the new dual-mode radio enables a redundant transmission line meeting all requirements with regard to real-time capability, robustness and transparency for the data bus. In addition, it provides a complementary transmission medium with regard to commonly used tethered links. A CAN bus system is used to demonstrate the redundant data transfer via tethered and wireless CAN.},
  language  = {en}
}
@inproceedings{KloeserKohlKraftetal.2021,
  author    = {Kl{\"o}ser, Lars and Kohl, Philipp and Kraft, Bodo and Z{\"u}ndorf, Albert},
  title     = {Multi-attribute relation extraction (MARE): simplifying the application of relation extraction},
  series = {Proceedings of the 2nd International Conference on Deep Learning Theory and Applications DeLTA - Volume 1},
  booktitle = {Proceedings of the 2nd International Conference on Deep Learning Theory and Applications DeLTA - Volume 1},
  publisher = {SciTePress},
  address   = {Set{\´u}bal},
  isbn      = {978-989-758-526-5},
  doi       = {10.5220/0010559201480156},
  pages     = {148 -- 156},
  year      = {2021},
  abstract  = {Natural language understanding's relation extraction makes innovative and encouraging novel business concepts possible and facilitates new digitilized decision-making processes. Current approaches allow the extraction of relations with a fixed number of entities as attributes. Extracting relations with an arbitrary amount of attributes requires complex systems and costly relation-trigger annotations to assist these systems. We introduce multi-attribute relation extraction (MARE) as an assumption-less problem formulation with two approaches, facilitating an explicit mapping from business use cases to the data annotations. Avoiding elaborated annotation constraints simplifies the application of relation extraction approaches. The evaluation compares our models to current state-of-the-art event extraction and binary relation extraction methods. Our approaches show improvement compared to these on the extraction of general multi-attribute relations.},
  language  = {en}
}
@inproceedings{AdenackerGerhardsOttenetal.2021,
  author    = {Adenacker, J. and Gerhards, Benjamin and Otten, Christian and Schleser, Markus},
  title     = {Laserstrahlschweißen von Aluminium-Kupfer-Werkstoffkombinationen f{\"u}r die Elektromobilit{\"a}t},
  series = {DVS CONGRESS 2021},
  booktitle = {DVS CONGRESS 2021},
  publisher = {DVS Media GmbH},
  address   = {D{\"u}sseldorf},
  isbn      = {978-3-96144-146-4},
  pages     = {31 -- 38},
  year      = {2021},
  language  = {de}
}
@article{Timme2021,
  author    = {Timme, Michael},
  title     = {Rechtsprechungs{\"u}bersicht zum Wohnraummietrecht},
  series = {Monatsschrift f{\"u}r Deutsches Recht},
  volume    = {75},
  journal   = {Monatsschrift f{\"u}r Deutsches Recht},
  number    = {1},
  publisher = {Verlag Dr. Otto Schmidt},
  address   = {K{\"o}ln},
  issn      = {2194-4202},
  doi       = {10.9785/mdtr-2021-750113},
  pages     = {6 -- 11},
  year      = {2021},
  language  = {de}
}
@book{Timme2021,
  author    = {Timme, Michael},
  title     = {BGB Crashkurs: der sichere Weg durch die Pr{\"u}fung},
  edition   = {6. Auflage},
  publisher = {C.H. Beck},
  address   = {M{\"u}nchen},
  isbn      = {978-3-406-77349-5},
  pages     = {160 Seiten},
  year      = {2021},
  abstract  = {Dieser "Crashkurs" eignet sich ausgezeichnet f{\"u}r die kompakte Wiederholung und die zielgerichtete Pr{\"u}fungsvorbereitung. Das Buch ist aufgrund seiner fallbezogenen Ausrichtung vor allem f{\"u}r Anf{\"a}nger gedacht, eignet sich aber auch f{\"u}r fortgeschrittene Studierende zur kompakten Wiederholung. Einfache Merks{\"a}tze, F{\"a}lle, {\"U}bersichten, Definitionen und kurze Zusammenfassungen lassen sich leicht einpr{\"a}gen und geben Sicherheit f{\"u}r die Pr{\"u}fung. Vorteile auf einen Blick: Das wichtigste BGB-Know-how als Repetitorium vor der Pr{\"u}fung, mit erprobten Merks{\"a}tzen und kurzen Zusammenfassungen, Fall f{\"u}r Fall sicher durch die Pr{\"u}fung},
  language  = {de}
}
@inproceedings{KohlSchmidtsKloeseretal.2021,
  author    = {Kohl, Philipp and Schmidts, Oliver and Kl{\"o}ser, Lars and Werth, Henri and Kraft, Bodo and Z{\"u}ndorf, Albert},
  title     = {STAMP 4 NLP - an agile framework for rapid quality-driven NLP applications development},
  series = {Quality of Information and Communications Technology. QUATIC 2021},
  booktitle = {Quality of Information and Communications Technology. QUATIC 2021},
  publisher = {Springer},
  address   = {Cham},
  isbn      = {978-3-030-85346-4},
  doi       = {10.1007/978-3-030-85347-1_12},
  pages     = {156 -- 166},
  year      = {2021},
  abstract  = {The progress in natural language processing (NLP) research over the last years, offers novel business opportunities for companies, as automated user interaction or improved data analysis. Building sophisticated NLP applications requires dealing with modern machine learning (ML) technologies, which impedes enterprises from establishing successful NLP projects. Our experience in applied NLP research projects shows that the continuous integration of research prototypes in production-like environments with quality assurance builds trust in the software and shows convenience and usefulness regarding the business goal. We introduce STAMP 4 NLP as an iterative and incremental process model for developing NLP applications. With STAMP 4 NLP, we merge software engineering principles with best practices from data science. Instantiating our process model allows efficiently creating prototypes by utilizing templates, conventions, and implementations, enabling developers and data scientists to focus on the business goals. Due to our iterative-incremental approach, businesses can deploy an enhanced version of the prototype to their software environment after every iteration, maximizing potential business value and trust early and avoiding the cost of successful yet never deployed experiments.},
  language  = {en}
}
@inproceedings{SchmidtsKraftWinkensetal.2021,
  author    = {Schmidts, Oliver and Kraft, Bodo and Winkens, Marvin and Z{\"u}ndorf, Albert},
  title     = {Catalog integration of heterogeneous and volatile product data},
  series = {DATA 2020: Data Management Technologies and Applications},
  booktitle = {DATA 2020: Data Management Technologies and Applications},
  publisher = {Springer},
  address   = {Cham},
  isbn      = {978-3-030-83013-7},
  doi       = {10.1007/978-3-030-83014-4_7},
  pages     = {134 -- 153},
  year      = {2021},
  abstract  = {The integration of frequently changing, volatile product data from different manufacturers into a single catalog is a significant challenge for small and medium-sized e-commerce companies. They rely on timely integrating product data to present them aggregated in an online shop without knowing format specifications, concept understanding of manufacturers, and data quality. Furthermore, format, concepts, and data quality may change at any time. Consequently, integrating product catalogs into a single standardized catalog is often a laborious manual task. Current strategies to streamline or automate catalog integration use techniques based on machine learning, word vectorization, or semantic similarity. However, most approaches struggle with low-quality or real-world data. We propose Attribute Label Ranking (ALR) as a recommendation engine to simplify the integration process of previously unknown, proprietary tabular format into a standardized catalog for practitioners. We evaluate ALR by focusing on the impact of different neural network architectures, language features, and semantic similarity. Additionally, we consider metrics for industrial application and present the impact of ALR in production and its limitations.},
  language  = {en}
}
@article{ZabirovSchleserBucherer2021,
  author    = {Zabirov, Alexander and Schleser, Markus and Bucherer, Sebastian},
  title     = {F{\"u}ge- und Dichtkonzept f{\"u}r einen Leichtbauverbrennungsmotor},
  series = {adh{\"a}sion KLEBEN \& DICHTEN},
  volume    = {65},
  journal   = {adh{\"a}sion KLEBEN \& DICHTEN},
  number    = {11},
  publisher = {Springer Nature},
  address   = {Cham},
  issn      = {2192-8681},
  doi       = {10.1007/s35145-021-0531-5},
  pages     = {12 -- 19},
  year      = {2021},
  language  = {de}
}
@incollection{PfetschAbeleAltherretal.2021,
  author    = {Pfetsch, Marc E. and Abele, Eberhard and Altherr, Lena and B{\"o}lling, Christian and Br{\"o}tz, Nicolas and Dietrich, Ingo and Gally, Tristan and Geßner, Felix and Groche, Peter and Hoppe, Florian and Kirchner, Eckhard and Kloberdanz, Hermann and Knoll, Maximilian and Kolvenbach, Philip and Kuttich-Meinlschmidt, Anja and Leise, Philipp and Lorenz, Ulf and Matei, Alexander and Molitor, Dirk A. and Niessen, Pia and Pelz, Peter F. and Rexer, Manuel and Schmitt, Andreas and Schmitt, Johann M. and Schulte, Fiona and Ulbrich, Stefan and Weigold, Matthias},
  title     = {Strategies for mastering uncertainty},
  series = {Mastering uncertainty in mechanical engineering},
  booktitle = {Mastering uncertainty in mechanical engineering},
  publisher = {Springer},
  address   = {Cham},
  isbn      = {978-3-030-78353-2},
  doi       = {10.1007/978-3-030-78354-9_6},
  pages     = {365 -- 456},
  year      = {2021},
  abstract  = {This chapter describes three general strategies to master uncertainty in technical systems: robustness, flexibility and resilience. It builds on the previous chapters about methods to analyse and identify uncertainty and may rely on the availability of technologies for particular systems, such as active components. Robustness aims for the design of technical systems that are insensitive to anticipated uncertainties. Flexibility increases the ability of a system to work under different situations. Resilience extends this characteristic by requiring a given minimal functional performance, even after disturbances or failure of system components, and it may incorporate recovery. The three strategies are described and discussed in turn. Moreover, they are demonstrated on specific technical systems.},
  language  = {en}
}
@article{Olbertz2021,
  author    = {Olbertz, Klaus},
  title     = {Wichtige arbeitsrechtliche Entwicklungen im Jahr 2020 : Der Jahresr{\"u}ckblick auf alles Wissenswerte im Arbeitsrecht des vergangenen Jahres},
  series = {NWB - Steuer- und Wirtschaftsrecht},
  journal   = {NWB - Steuer- und Wirtschaftsrecht},
  number    = {10},
  issn      = {0028-3460},
  pages     = {703 -- 715},
  year      = {2021},
  abstract  = {Im Anschluss an die arbeitsrechtlichen Jahres{\"u}bersichten der vergangenen Jahre (NWB 5/2019 S. 266; NWB 8/2020 S. 557) gibt der nachfolgende Beitrag einen {\"U}berblick {\"u}ber relevante Entwicklungen im Arbeitsrecht des Jahres 2020. Der erste Teil besch{\"a}ftigt sich hierbei mit gesetzlichen {\"A}nderungen. Neben Regelungen, die auf die COVID-19-Pandemie zur{\"u}ckgef{\"u}hrt werden k{\"o}nnen, hat der Gesetzgeber auch andere Vorhaben umgesetzt. So wurde u. a. das Arbeitnehmerentsenderecht reformiert. F{\"u}r Diskussionen sorgt(e) zudem das Gesetzesvorhaben zur Regelung mobiler Arbeit. Im zweiten Teil werden f{\"u}r die Praxis wichtige h{\"o}chstrichterliche Gerichtsentscheidungen zum Arbeitsrecht erl{\"a}utert, alphabetisch sortiert von A (wie Antidiskriminierungsrecht) bis U (wie Urlaub).},
  language  = {de}
}
@article{Olbertz2021,
  author    = {Olbertz, Klaus},
  title     = {Die Flexibilisierung von Arbeitszeit durch den Abruf von Arbeit : M{\"o}glichkeiten und Grenzen arbeitsvertraglicher Gestaltung zur Vermeidung von „Leerlaufzeiten"},
  series = {NWB - Steuer- und Wirtschaftsrecht},
  journal   = {NWB - Steuer- und Wirtschaftsrecht},
  number    = {15},
  issn      = {0028-3460},
  pages     = {1055 -- 1063},
  year      = {2021},
  abstract  = {Die Arbeitswelt ist im Umbruch. Der Bedarf an flexiblen Arbeitszeitmodellen nimmt stetig zu, wobei die Corona-Pandemie dieses Bed{\"u}rfnis nochmals versch{\"a}rft hat. Gerade auch in kleineren und mittleren Unternehmen w{\"a}chst die Notwendigkeit, den Einsatz der Besch{\"a}ftigten m{\"o}glichst bedarfsgerecht zu steuern, also bei guter Auftragslage mehr Arbeitszeit abzurufen und bei ausbleibenden Auftr{\"a}gen die Arbeitszeit zu reduzieren und somit bezahlte „Leerlaufzeiten" zu vermeiden. Der Gesetzgeber stellt den Arbeitgebern hierf{\"u}r das Instrument der sog. Abrufarbeit ( \S 12 Teilzeit- und Befristungsgesetz - TzBfG ) zur Verf{\"u}gung. In dem nachfolgenden Beitrag werden M{\"o}glichkeiten und Grenzen der Abrufarbeit skizziert und konkrete arbeitsvertragliche Gestaltungsm{\"o}glichkeiten aufgezeigt.},
  language  = {de}
}
@article{Olbertz2021,
  author    = {Olbertz, Klaus},
  title     = {Vertragsgestaltungen bei der Besch{\"a}ftigung von Rentnern in Unternehmen : (Befristete) Besch{\"a}ftigungsverh{\"a}ltnisse als sinnvolles Instrument zum Schließen von Personall{\"u}cken},
  series = {NWB - Steuer- und Wirtschaftsrecht},
  journal   = {NWB - Steuer- und Wirtschaftsrecht},
  number    = {25},
  issn      = {0028-3460},
  pages     = {1810 -- 1817},
  year      = {2021},
  language  = {de}
}
@article{BraunChengDoweyetal.2021,
  author    = {Braun, Sebastian and Cheng, Chi-Tsun and Dowey, Steve and Wollert, J{\"o}rg},
  title     = {Performance evaluation of skill-based order-assignment in production environments with multi-agent systems},
  series = {IEEE Journal of Emerging and Selected Topics in Industrial Electronics},
  journal   = {IEEE Journal of Emerging and Selected Topics in Industrial Electronics},
  number    = {Early Access},
  publisher = {IEEE},
  address   = {New York},
  issn      = {2687-9735},
  doi       = {10.1109/JESTIE.2021.3108524},
  year      = {2021},
  abstract  = {The fourth industrial revolution introduces disruptive technologies to production environments. One of these technologies are multi-agent systems (MASs), where agents virtualize machines. However, the agent's actual performances in production environments can hardly be estimated as most research has been focusing on isolated projects and specific scenarios. We address this gap by implementing a highly connected and configurable reference model with quantifiable key performance indicators (KPIs) for production scheduling and routing in single-piece workflows. Furthermore, we propose an algorithm to optimize the search of extrema in highly connected distributed systems. The benefits, limits, and drawbacks of MASs and their performances are evaluated extensively by event-based simulations against the introduced model, which acts as a benchmark. Even though the performance of the proposed MAS is, on average, slightly lower than the reference system, the increased flexibility allows it to find new solutions and deliver improved factory-planning outcomes. Our MAS shows an emerging behavior by using flexible production techniques to correct errors and compensate for bottlenecks. This increased flexibility offers substantial improvement potential. The general model in this paper allows the transfer of the results to estimate real systems or other models.},
  language  = {en}
}
@phdthesis{Bayer2021,
  author    = {Bayer, Robin},
  title     = {Development of a novel in-vitro vascular model for determination of physiological and pathophysiological mechanobiology},
  publisher = {Universit{\"a}t zu K{\"o}ln},
  address   = {K{\"o}ln},
  url       = {http://nbn-resolving.de/urn:nbn:de:hbz:38-362212},
  pages     = {IV, 115 Seiten},
  year      = {2021},
  language  = {en}
}
@article{MolinnusDrinicIkenetal.2021,
  author    = {Molinnus, Denise and Drinic, Aleksander and Iken, Heiko and Kr{\"o}ger, Nadja and Zinser, Max and Smeets, Ralf and K{\"o}pf, Marius and Kopp, Alexander and Sch{\"o}ning, Michael Josef},
  title     = {Towards a flexible electrochemical biosensor fabricated from biocompatible Bombyx mori silk},
  series = {Biosensors and Bioelectronics},
  volume    = {183},
  journal   = {Biosensors and Bioelectronics},
  number    = {Art. 113204},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0956-5663},
  doi       = {10.1016/j.bios.2021.113204},
  year      = {2021},
  language  = {en}
}
@article{Fissabre2021,
  author    = {Fissabre, Anke},
  title     = {Ein pazifistisches Kriegerdenkmal der Moderne. Das Totenkreuz von Rudolf Schwarz},
  series = {In situ: Zeitschrift f{\"u}r Architekturgeschichte},
  journal   = {In situ: Zeitschrift f{\"u}r Architekturgeschichte},
  number    = {1},
  publisher = {Wernersche Verlagsgesellschaft},
  address   = {Worms},
  issn      = {1866-959X},
  pages     = {127 -- 138},
  year      = {2021},
  language  = {de}
}
@article{HennesLaumann2021,
  author    = {Hennes, Philipp and Laumann, J{\"o}rg},
  title     = {Ansatz der Drehbehinderung aus Koppelpfetten mit d{\"u}nnwandigen kaltgeformten Z-Profilen},
  series = {Stahlbau},
  volume    = {90},
  journal   = {Stahlbau},
  number    = {3},
  publisher = {Ernst \& Sohn},
  address   = {Berlin},
  issn      = {1437-1049},
  doi       = {10.1002/stab.202000104},
  pages     = {158 -- 168},
  year      = {2021},
  language  = {de}
}
@article{YoshinobuSchoening2021,
  author    = {Yoshinobu, Tatsuo and Sch{\"o}ning, Michael Josef},
  title     = {Light-addressable potentiometric sensors (LAPS) for cell monitoring and biosensing},
  series = {Current Opinion in Electrochemistry},
  journal   = {Current Opinion in Electrochemistry},
  number    = {In Press, Journal Pre-proof},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {2451-9103},
  doi       = {10.1016/j.coelec.2021.100727},
  year      = {2021},
  language  = {en}
}
@article{Maurischat2021,
  author    = {Maurischat, Andreas},
  title     = {Algebraic independence of the Carlitz period and its hyperderivatives},
  pages     = {1 -- 12},
  year      = {2021},
  language  = {en}
}
@article{WertIkenSchoeningetal.2021,
  author    = {Wert, Stefan and Iken, Heiko and Sch{\"o}ning, Michael Josef and Matysik, Frank-Michael},
  title     = {Development of a temperature-pulse enhanced electrochemical glucose biosensor and characterization of its stability via scanning electrochemical microscopy},
  series = {Electroanalysis},
  journal   = {Electroanalysis},
  number    = {Early View},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {1521-4109},
  doi       = {10.1002/elan.202100089},
  year      = {2021},
  abstract  = {Glucose oxidase (GOx) is an enzyme frequently used in glucose biosensors. As increased temperatures can enhance the performance of electrochemical sensors, we investigated the impact of temperature pulses on GOx that was drop-coated on flattened Pt microwires. The wires were heated by an alternating current. The sensitivity towards glucose and the temperature stability of GOx was investigated by amperometry. An up to 22-fold increase of sensitivity was observed. Spatially resolved enzyme activity changes were investigated via scanning electrochemical microscopy. The application of short (<100 ms) heat pulses was associated with less thermal inactivation of the immobilized GOx than long-term heating.},
  language  = {en}
}
@article{LowisFergusonPaulssenetal.2021,
  author    = {Lowis, Carsten and Ferguson, Simon and Paulßen, Elisabeth and Hoehr, Cornelia},
  title     = {Improved Sc-44 production in a siphon-style liquid target on a medical cyclotron},
  series = {Applied Radiation and Isotopes},
  volume    = {172},
  journal   = {Applied Radiation and Isotopes},
  number    = {Art. 109675},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0969-8043},
  doi       = {10.1016/j.apradiso.2021.109675},
  year      = {2021},
  language  = {en}
}
@article{WaldvogelRitzmannFreyleretal.2021,
  author    = {Waldvogel, Janice and Ritzmann, Ramona and Freyler, Kathrin and Helm, Michael and Monti, Elena and Albracht, Kirsten and St{\"a}udle, Benjamin and Gollhofer, Albert and Narici, Marco},
  title     = {The Anticipation of Gravity in Human Ballistic Movement},
  series = {Frontiers in Physiology},
  journal   = {Frontiers in Physiology},
  publisher = {Frontiers},
  address   = {Lausanne},
  issn      = {1664-042X},
  doi       = {10.3389/fphys.2021.614060},
  year      = {2021},
  abstract  = {Stretch-shortening type actions are characterized by lengthening of the pre-activated muscle-tendon unit (MTU) in the eccentric phase immediately followed by muscle shortening. Under 1 g, pre-activity before and muscle activity after ground contact, scale muscle stiffness, which is crucial for the recoil properties of the MTU in the subsequent push-off. This study aimed to examine the neuro-mechanical coupling of the stretch-shortening cycle in response to gravity levels ranging from 0.1 to 2 g. During parabolic flights, 17 subjects performed drop jumps while electromyography (EMG) of the lower limb muscles was combined with ultrasound images of the gastrocnemius medialis, 2D kinematics and kinetics to depict changes in energy management and performance. Neuro-mechanical coupling in 1 g was characterized by high magnitudes of pre-activity and eccentric muscle activity allowing an isometric muscle behavior during ground contact. EMG during pre-activity and the concentric phase systematically increased from 0.1 to 1 g. Below 1 g the EMG in the eccentric phase was diminished, leading to muscle lengthening and reduced MTU stretches. Kinetic energy at take-off and performance were decreased compared to 1 g. Above 1 g, reduced EMG in the eccentric phase was accompanied by large MTU and muscle stretch, increased joint flexion amplitudes, energy loss and reduced performance. The energy outcome function established by linear mixed model reveals that the central nervous system regulates the extensor muscles phase- and load-specifically. In conclusion, neuro-mechanical coupling appears to be optimized in 1 g. Below 1 g, the energy outcome is compromised by reduced muscle stiffness. Above 1 g, loading progressively induces muscle lengthening, thus facilitating energy dissipation.},
  language  = {en}
}
@article{BohndickBosseJaenschetal.2021,
  author    = {Bohndick, Carla and Bosse, Elke and J{\"a}nsch, Vanessa K. and Barnat, Miriam},
  title     = {How different diversity factors affect the perception of first-year requirements in higher education},
  series = {Frontline Learning Research},
  volume    = {9},
  journal   = {Frontline Learning Research},
  number    = {2},
  publisher = {EARLI},
  issn      = {2295-3159},
  doi       = {10.14786/flr.v9i2.667},
  pages     = {78 -- 95},
  year      = {2021},
  abstract  = {In the light of growing university entry rates, higher education institutions not only serve larger numbers of students, but also seek to meet first-year students' ever more diverse needs. Yet to inform universities how to support the transition to higher education, research only offers limited insights. Current studies tend to either focus on the individual factors that affect student success or they highlight students' social background and their educational biography in order to examine the achievement of selected, non-traditional groups of students. Both lines of research appear to lack integration and often fail to take organisational diversity into account, such as different types of higher education institutions or degree programmes. For a more comprehensive understanding of student diversity, the present study includes individual, social and organisational factors. To gain insights into their role for the transition to higher education, we examine how the different factors affect the students' perception of the formal and informal requirements of the first year as more or less difficult to cope with. As the perceived requirements result from both the characteristics of the students and the institutional context, they allow to investigate transition at the interface of the micro and the meso level of higher education. Latent profile analyses revealed that there are no profiles with complex patterns of perception of the first-year requirements, but the identified groups rather differ in the overall level of perceived challenges. Moreover, SEM indicates that the differences in the perception largely depend on the individual factors self-efficacy and volition.},
  language  = {en}
}
@article{HugenrothNeidlinEngelmannetal.2021,
  author    = {Hugenroth, Kristin and Neidlin, Michael and Engelmann, Ulrich M. and Kaufmann, Tim A. S. and Steinseifer, Ulrich and Heilmann, Torsten},
  title     = {Tipless Transseptal Cannula Concept Combines Improved Hemodynamic Properties and Risk-Reduced Placement: an In Silico Proof-of-Concept},
  series = {Artificial Organs},
  journal   = {Artificial Organs},
  number    = {Accepted Article},
  publisher = {Wiley},
  address   = {Weinheim},
  issn      = {1525-1594},
  doi       = {10.1111/aor.13964},
  year      = {2021},
  language  = {en}
}
@article{GivanoudiCornelisRasschaertetal.2021,
  author    = {Givanoudi, Stella and Cornelis, Peter and Rasschaert, Geertrui and Wackers, Gideon and Iken, Heiko and Rolka, David and Yongabi, Derick and Robbens, Johan and Sch{\"o}ning, Michael Josef and Heyndrickx, Marc and Wagner, Patrick},
  title     = {Selective Campylobacter detection and quantification in poultry: A sensor tool for detecting the cause of a common zoonosis at its source},
  series = {Sensors and Actuators B: Chemical},
  journal   = {Sensors and Actuators B: Chemical},
  number    = {In Press, Journal Pre-proof},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0925-4005},
  doi       = {10.1016/j.snb.2021.129484},
  pages     = {Article 129484},
  year      = {2021},
  language  = {en}
}
@inproceedings{UlmerBraunWollert2021,
  author    = {Ulmer, Jessica and Braun, Sebastian and Wollert, J{\"o}rg},
  title     = {Adaptive VR-Produktionsumgebungen f{\"u}r Evaluations- und Schulungst{\"a}tigkeiten},
  series = {Automation 2021: Navigating towards resilient Production},
  booktitle = {Automation 2021: Navigating towards resilient Production},
  publisher = {VDI},
  address   = {D{\"u}sseldorf},
  isbn      = {978-3-18-092392-5},
  issn      = {0083-5560},
  doi       = {10.51202/9783181023921-55},
  pages     = {55 -- 64},
  year      = {2021},
  abstract  = {Industrie 4.0 stellt viele Herausforderungen an produzierende Unternehmen und ihre Besch{\"a}f-tigten. Innovative und effektive Trainingsstrategien sind erforderlich, um mit den sich schnell ver{\"a}ndernden Produktionsumgebungen und neuen Fertigungstechnologien Schritt halten zu k{\"o}nnen. Virtual Reality (VR) bietet neue M{\"o}glichkeiten f{\"u}r On-the-Job, On-Demand- und Off-Premise-Schulungen. Diese Arbeit stellt ein neues VR Schulungssystem vor, welches sich flexible an unterschiedliche Trainingsobjekte auf Grundlage von Rezepten und CAD Modellen anpassen l{\"a}sst. Das Konzept basiert auf gerichteten azyklischen Graphen und einem Level-system. Es erm{\"o}glicht eine benutzerindividuelle Lerngeschwindigkeit mittels visueller Ele-mente. Das Konzept wurde f{\"u}r einen mechanischen Anwendungsfall mit Industriekomponen-ten implementiert und in der Industrie 4.0-Modellfabrik der FH Aachen umgesetzt.},
  language  = {de}
}
@techreport{GoellBraunsteinAlbracht2021,
  author    = {G{\"o}ll, Fabian and Braunstein, Bj{\"o}rn and Albracht, Kirsten},
  title     = {Lernende roboterassistierte Systeme f{\"u}r das neuromuskul{\"a}re Training - RoSylerNT; Teilvorhaben: Entwicklung eines neuromuskuloskelettalen Modells als Basis f{\"u}r die Interaktionsf{\"a}higkeiten autonomer Assistenzsysteme},
  publisher = {Deutsche Sporthochschule K{\"o}ln},
  address   = {K{\"o}ln},
  doi       = {10.2314/KXP:1855318741},
  pages     = {14 Seiten},
  year      = {2021},
  language  = {de}
}
@article{WerkhausenWillwacherAlbracht2021,
  author    = {Werkhausen, Amelie and Willwacher, Steffen and Albracht, Kirsten},
  title     = {Medial gastrocnemius muscle fascicles shorten throughout stance during sprint acceleration},
  series = {Scandinavian Journal of Medicine \& Science in Sports},
  volume    = {31},
  journal   = {Scandinavian Journal of Medicine \& Science in Sports},
  number    = {7},
  publisher = {Wiley-Blackwell},
  address   = {Oxford},
  issn      = {0905-7188 (Druckausgabe)},
  doi       = {10.1111/sms.13956},
  pages     = {1471 -- 1480},
  year      = {2021},
  abstract  = {The compliant nature of distal limb muscle-tendon units is traditionally considered suboptimal in explosive movements when positive joint work is required. However, during accelerative running, ankle joint net mechanical work is positive. Therefore, this study aims to investigate how plantar flexor muscle-tendon behavior is modulated during fast accelerations. Eleven female sprinters performed maximum sprint accelerations from starting blocks, while gastrocnemius muscle fascicle lengths were estimated using ultrasonography. We combined motion analysis and ground reaction force measurements to assess lower limb joint kinematics and kinetics, and to estimate gastrocnemius muscle-tendon unit length during the first two acceleration steps. Outcome variables were resampled to the stance phase and averaged across three to five trials. Relevant scalars were extracted and analyzed using one-sample and two-sample t-tests, and vector trajectories were compared using statistical parametric mapping. We found that an uncoupling of muscle fascicle behavior from muscle-tendon unit behavior is effectively used to produce net positive mechanical work at the joint during maximum sprint acceleration. Muscle fascicles shortened throughout the first and second steps, while shortening occurred earlier during the first step, where negative joint work was lower compared with the second step. Elastic strain energy may be stored during dorsiflexion after touchdown since fascicles did not lengthen at the same time to dissipate energy. Thus, net positive work generation is accommodated by the reuse of elastic strain energy along with positive gastrocnemius fascicle work. Our results show a mechanism of how muscles with high in-series compliance can contribute to net positive joint work.},
  language  = {en}
}
@article{MontiWaldvogelRitzmannetal.2021,
  author    = {Monti, Elena and Waldvogel, Janice and Ritzmann, Ramona and Freyler, Kathrin and Albracht, Kirsten and Helm, Michael and De Cesare, Niccol{\`o} and Pavan, Piero and Reggiani, Carlo and Gollhofer, Albert and Narici, Marco Vincenzo},
  title     = {Muscle in variable gravity: "I do not know where I am, but I know what to do"},
  series = {Frontiers in Physiology},
  volume    = {12},
  journal   = {Frontiers in Physiology},
  publisher = {Frontiers Research Foundation},
  address   = {Lausanne},
  issn      = {1664-042X},
  doi       = {10.3389/fphys.2021.714655},
  pages     = {19 Seiten},
  year      = {2021},
  abstract  = {Performing tasks, such as running and jumping, requires activation of the agonist and antagonist muscles before (motor unit pre-activation) and during movement performance (Santello and Mcdonagh, 1998). A well-timed and regulated muscle activation elicits a stretch-shortening cycle (SSC) response, naturally occurring in bouncing movements (Ishikawa and Komi, 2004; Taube et al., 2012). By definition, the SSC describes the stretching of a pre-activated muscle-tendon complex immediately followed by a muscle shortening in the concentric push-off phase (Komi, 1984). Given the importance of SSC actions for human movement, it is not surprising that many studies investigated the biomechanics of this phenomenon; in particular, drop jumps (DJs) represent a good paradigm to study muscle fascicle and tendon behavior in ballistic movements involving the SSC. Within a DJ, three main phases [pre-activation, braking, and push-off (PO; Komi, 2000)] have been recognized and extensively studied in common and challenging conditions, such as changes in load, falling height, or simulated hypo-gravity (Avela et al., 1994; Arampatzis et al., 2001; Fukashiro et al., 2005; Ishikawa et al., 2005; Sousa et al., 2007; Ritzmann et al., 2016; Helm et al., 2020). These studies show that the timing and amount of triceps-surae muscle-tendon unit pre-activation in DJs are differentially regulated based on the load applied to the muscle, being optimal in normal "Earth" gravity conditions (Avela et al., 1994), but decreased in simulated hypo-gravity, hyper-gravity (Avela et al., 1994; Ritzmann et al., 2016), or unknown conditions (i.e., unknown falling heights; Helm et al., 2020). Some authors indicated that, when falling from heights different from the optimal one [defined as the drop height giving a maximum DJ performance indicated as peak ground reaction force (GRF) or jump high], electromyographic (EMG) activity of the plantar flexors increases from lower than optimal to higher than optimal heights (Ishikawa and Komi, 2004; Sousa et al., 2007). These findings highlight the ability of the central nervous system to regulate the timing and amount of pre-activation according to different jumping conditions, thus regulating muscle fascicle length, tendon and joint stiffness as well as position, in order to safely land on the ground and quickly re-bounce. Similarly, to pre-activation, also in the braking phase, the plantar flexors are differentially regulated. In optimal height (i.e., load) jumping conditions, gastrocnemius medialis (GM) fascicles shorten at early ground contact (possibly due to the intervention of the stretch reflex; Gollhofer et al., 1992) and behave quasi-isometrically in the late braking phase, enabling tendon elongation, and storage of elastic energy (Gollhofer et al., 1992; Fukashiro et al., 2005; Sousa et al., 2007). When increasing the falling height (augmenting the impact GRF), the quasi-isometric behavior of fascicles disappears, and fast fascicle lengthening occurs (Ishikawa et al., 2005; Sousa et al., 2007). In the third and last PO phase, fascicles shorten and the tendon releases the elastic energy previously stored. Bobbert et al. (1987) reported no influence of jumping height on the work done and on the net vertical impulse assessed during PO; this observation suggests that, despite an optimal DJ performance might be achieved only in specific conditions (falling heights, loads), the central nervous system seems to be able to regulate muscle behavior in order to effectively perform the required task also in challenging situations. Although the regulation of triceps-surae muscle-tendon unit in DJs has been extensively investigated, very few studies focused on sarcomeres behavior during the performance of this SSC movement (Kurokawa et al., 2003; Fukashiro et al., 2005, 2006). Sarcomeres represent muscle contractile units and are known to express different amounts of force depending on their length (Gordon et al., 1966; Walker and Schrodt, 1974); thus, understanding the time course of their responses during DJs is fundamental to gain further insights into muscle force-generating capacity. In vivo measurement of sarcomere length in humans has been so far been performed only in static positions and under highly controlled experimental conditions (Llewellyn et al., 2008; Sanchez et al., 2015). Instead, human sarcomere length estimation (achieved by dividing GM measured fascicle length for a fixed sarcomere number) in dynamic contractions provided an indirect measure of sarcomere operating range during squat jump, countermovement jump, and DJ (Fukashiro et al., 2005, 2006; Kurokawa et al., 2003). The results of these studies showed that sarcomeres operate in the ascending limb of their length-tension (L-T) relationship in all types of jumps, and particularly so in DJ. However, most of the available observations on sarcomere and muscle fascicle behavior were made in condition of constant gravity. Thus, in order to understand how sarcomere and muscle fascicle length are regulated in variable gravity conditions, we performed experiments in a parabolic flight, involving variable gravity levels, ranging from about zero-g to about double the Earth's gravity (1 g; Waldvogel et al., 2021). Specifically, the aims of the present study were as follows: 1. To investigate the ability of the neuromuscular system in regulating fascicle length in response to conditions of variable gravity. 2. To estimate sarcomere operative length in the different DJ phases, in order to calculate its theoretical force production and its possible modulation in conditions of variable gravity. We hypothesized that muscle fascicles would be differentially regulated in different gravity conditions compared to 1 g, particularly in anticipation of landing and re-bouncing in unknown gravity levels. In addition, we hypothesized that sarcomeres would operate in the upper part of the ascending limb of their L-T relationship, possibly lengthening during the braking phase (especially in hyper-gravity) while operating quasi-isometrically in 1 g.},
  language  = {en}
}
@article{StaeudleSeynnesLapsetal.2021,
  author    = {St{\"a}udle, Benjamin and Seynnes, Olivier and Laps, Guido and G{\"o}ll, Fabian and Br{\"u}ggemann, Gert-Peter and Albracht, Kirsten},
  title     = {Recovery from achilles tendon repair: a combination of Postsurgery Outcomes and Insufficient remodeling of muscle and tendon},
  series = {Medicine \& Science in Sports \& Exercise},
  volume    = {53},
  journal   = {Medicine \& Science in Sports \& Exercise},
  number    = {7},
  publisher = {American College of Sports Medicine},
  address   = {Philadelphia, Pa.},
  issn      = {1530-0315},
  doi       = {10.1249/MSS.0000000000002592},
  pages     = {1356 -- 1366},
  year      = {2021},
  abstract  = {Achilles tendon rupture (ATR) patients have persistent functional deficits in the triceps surae muscle-tendon unit (MTU). The complex remodeling of the MTU accompanying these deficits remains poorly understood. The purpose of the present study was to associate in vivo and in silico data to investigate the relations between changes inMTU properties and strength deficits inATR patients. Methods: Elevenmale subjects who had undergone surgical repair of complete unilateral ATR were examined 4.6 ± 2.0 (mean ± SD) yr after rupture. Gastrocnemius medialis (GM) tendon stiffness, morphology, and muscle architecture were determined using ultrasonography. The force-length relation of the plantar flexor muscles was assessed at five ankle joint angles. In addition, simulations (OpenSim) of the GM MTU force-length properties were performed with various iterations of MTU properties found between the unaffected and the affected side. Results: The affected side of the patients displayed a longer, larger, and stiffer GM tendon (13\% ± 10\%, 105\% ± 28\%, and 54\% ± 24\%, respectively) compared with the unaffected side. The GM muscle fascicles of the affected side were shorter (32\% ± 12\%) and with greater pennation angles (31\% ± 26\%). A mean deficit in plantarflexion moment of 31\% ± 10\% was measured. Simulations indicate that pairing an intact muscle with a longer tendon shifts the optimal angular range of peak force outside physiological angular ranges, whereas the shorter muscle fascicles and tendon stiffening seen in the affected side decrease this shift, albeit incompletely. Conclusions: These results suggest that the substantial changes in MTU properties found in ATR patients may partly result from compensatory remodeling, although this process appears insufficient to fully restore muscle function.},
  language  = {en}
}
@inproceedings{SchulzeBuxlohGross2021,
  author    = {Schulze-Buxloh, Lina and Groß, Rolf Fritz},
  title     = {Interdisciplinary Course Smart Building Engineering: A new approach of teaching freshmen in remote teamwork project under pandemic restrictions},
  series = {New Perspectives in Science Education - International Conference},
  booktitle = {New Perspectives in Science Education - International Conference},
  publisher = {Filodiritto},
  address   = {Bologna},
  pages     = {4 Seiten},
  year      = {2021},
  abstract  = {In the context of the Corona pandemic and its impact on teaching like digital lectures and exercises a new concept especially for freshmen in demanding courses of Smart Building Engineering became necessary. As there were hardly any face-to-face events at the university, the new teaching concept should enable a good start into engineering studies under pandemic conditions anyway and should also replace the written exam at the end. The students should become active themselves in small teams instead of listening passively to a lecture broadcast online with almost no personal contact. For this purpose, a role play was developed in which the freshmen had to work out a complete solution to the realistic problem of designing, construction planning and implementing a small guesthouse. Each student of the team had to take a certain role like architect, site manager, BIM-manager, electrician and the technitian for HVAC installations. Technical specifications must be complied with, as well as documentation, time planning and cost estimate. The final project folder had to contain technical documents like circuit diagrams for electrical components, circuit diagrams for water and heating, design calculations and components lists. On the other hand construction schedule, construction implementation plan, documentation of the construction progress and minutes of meetings between the various trades had to be submitted as well. In addition to the project folder, a model of the construction project must also be created either as a handmade model or as a digital 3D-model using Computer-aided design (CAD) software. The first steps in the field of Building information modelling (BIM) had also been taken by creating a digital model of the building showing the current planning status in real time as a digital twin. This project turned out to be an excellent training of important student competencies like teamwork, communication skills, and self -organisation and also increased motivation to work on complex technical questions. The aim of giving the student a first impression on the challenges and solutions in building projects with many different technical trades and their points of view was very well achieved and should be continued in the future.},
  language  = {en}
}
@inproceedings{SchulzeBuxlohGross2021,
  author    = {Schulze-Buxloh, Lina and Groß, Rolf Fritz},
  title     = {Miniature urban farming plant: a complex educational "Toy" for engineering students},
  series = {The Future of Education 11th Edition 2021},
  booktitle = {The Future of Education 11th Edition 2021},
  pages     = {4 Seiten},
  year      = {2021},
  abstract  = {Urban farming is an innovative and sustainable way of food production and is becoming more and more important in smart city and quarter concepts. It also enables the production of certain foods in places where they usually dare not produced, such as production of fish or shrimps in large cities far away from the coast. Unfortunately, it is not always possible to show students such concepts and systems in real life as part of courses: visits of such industry plants are sometimes not possible because of distance or are permitted by the operator for hygienic reasons. In order to give the students the opportunity of getting into contact with such an urban farming system and its complex operation, an industrial urban farming plant was set up on a significantly smaller scale. Therefore, all needed technical components like water aeriation, biological and mechanical filtration or water circulation have been replaced either by aquarium components or by self-designed parts also using a 3D-printer. Students from different courses like mechanical engineering, smart building engineering, biology, electrical engineering, automation technology and civil engineering were involved in this project. This "miniature industrial plant" was also able to start operation and has now been running for two years successfully. Due to Corona pandemic, home office and remote online lectures, the automation of this miniature plant should be brought to a higher level in future for providing a good control over the system and water quality remotely. The aim of giving the student a chance to get to know the operation of an urban farming plant was very well achieved and the students had lots of fun in "playing" and learning with it in a realistic way.},
  language  = {en}
}
@inproceedings{SchulzeBuxlohGrossUlbrich2021,
  author    = {Schulze-Buxloh, Lina and Groß, Rolf Fritz and Ulbrich, Michelle},
  title     = {Digital planning using building information modelling and virtual reality: new approach for students' remote practical training under lockdown conditions in the course of smart building engineering},
  series = {Proceedings of International Conference on Education in Mathematics, Science and Technology 2021},
  booktitle = {Proceedings of International Conference on Education in Mathematics, Science and Technology 2021},
  publisher = {ISTES Organization},
  address   = {San Antonio, TX},
  isbn      = {978-1-952092-17-6},
  pages     = {118 -- 123},
  year      = {2021},
  abstract  = {The worldwide Corona pandemic has severely restricted student projects in the higher semesters of engineering courses. In order not to delay the graduation, a new concept had to be developed for projects under lockdown conditions. Therefore, unused rooms at the university should be digitally recorded in order to develop a new usage concept as laboratory rooms. An inventory of the actual state of the rooms was done first by taking photos and listing up all flaws and peculiarities. After that, a digital site measuring was done with a 360° laser scanner and these recorded scans were linked to a coherent point cloud and transferred to a software for planning technical building services and supporting Building Information Modelling (BIM). In order to better illustrate the difference between the actual and target state, two virtual reality models were created for realistic demonstration. During the project, the students had to go through the entire digital planning phases. Technical specifications had to be complied with, as well as documentation, time planning and cost estimate. This project turned out to be an excellent alternative to on-site practical training under lockdown conditions and increased the students' motivation to deal with complex technical questions.},
  language  = {en}
}
@article{NeumaierWeissVeldemanetal.2021,
  author    = {Neumaier, Felix and Weiss, Miriam and Veldeman, Michael and Kotliar, Konstantin and Wiesmann, Martin and Schulze-Steinen, Henna and H{\"o}llig, Anke and Clusmann, Hans and Schubert, Gerrit Alexander and Albanna, Walid},
  title     = {Changes in endogenous daytime melatonin levels after aneurysmal subarachnoid hemorrhage - preliminary findings from an observational cohort study},
  series = {Clinical Neurology and Neurosurgery},
  volume    = {208},
  journal   = {Clinical Neurology and Neurosurgery},
  number    = {Article No.: 106870},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0303-8467},
  doi       = {10.1016/j.clineuro.2021.106870},
  year      = {2021},
  abstract  = {Aneurysmal subarachnoid hemorrhage (aSAH) is associated with early and delayed brain injury due to several underlying and interrelated processes, which include inflammation, oxidative stress, endothelial, and neuronal apoptosis. Treatment with melatonin, a cytoprotective neurohormone with anti-inflammatory, anti-oxidant and anti-apoptotic effects, has been shown to attenuate early brain injury (EBI) and to prevent delayed cerebral vasospasm in experimental aSAH models. Less is known about the role of endogenous melatonin for aSAH outcome and how its production is altered by the pathophysiological cascades initiated during EBI. In the present observational study, we analyzed changes in melatonin levels during the first three weeks after aSAH.},
  language  = {en}
}
@article{KuertenKotliarFuestetal.2021,
  author    = {Kuerten, David and Kotliar, Konstantin and Fuest, Matthias and Walter, Peter and Hollstein, Muriel and Plange, Niklas},
  title     = {Does hemispheric vascular regulation differ significantly in glaucoma patients with altitudinal visual field asymmetry? A single-center, prospective study},
  series = {International Ophthalmology},
  volume    = {41},
  journal   = {International Ophthalmology},
  number    = {41},
  editor    = {Neri, Piergiorgio},
  publisher = {Springer},
  address   = {Berlin},
  isbn      = {1573-2630},
  doi       = {10.1007/s10792-021-01876-0},
  pages     = {3109 -- 3119},
  year      = {2021},
  abstract  = {Purpose Vascular risk factors and ocular perfusion are heatedly discussed in the pathogenesis of glaucoma. The retinal vessel analyzer (RVA, IMEDOS Systems, Germany) allows noninvasive measurement of retinal vessel regulation. Significant differences especially in the veins between healthy subjects and patients suffering from glaucoma were previously reported. In this pilot-study we investigated if localized vascular regulation is altered in glaucoma patients with altitudinal visual field defect asymmetry. Methods 15 eyes of 12 glaucoma patients with advanced altitudinal visual field defect asymmetry were included. The mean defect was calculated for each hemisphere separately (-20.99 ± 10.49 pro- found hemispheric visual field defect vs -7.36 ± 3.97 dB less profound hemisphere). After pupil dilation, RVA measurements of retinal arteries and veins were conducted using the standard protocol. The superior and inferior retinal vessel reactivity were measured consecutively in each eye. Results Significant differences were recorded in venous vessel constriction after flicker light stimulation and overall amplitude of the reaction (p \ 0.04 and p \ 0.02 respectively) in-between the hemispheres spheres. Vessel reaction was higher in the hemisphere corresponding to the more advanced visual field defect. Arterial diameters reacted similarly, failing to reach statistical significance. Conclusion Localized retinal vessel regulation is significantly altered in glaucoma patients with asymmetri altitudinal visual field defects. Veins supplying the hemisphere concordant to a less profound visual field defect show diminished diameter changes. Vascular dysregulation might be particularly important in early glaucoma stages prior to a significant visual field defect.},
  language  = {en}
}
@article{AlbannaConzenWeissetal.2021,
  author    = {Albanna, Walid and Conzen, Catharina and Weiss, Miriam and Seyfried, Katharina and Kotliar, Konstantin and Schmidt, Tobias Philip and Kuerten, David and Hescheler, J{\"u}rgen and Bruecken, Anne and Schmidt-Trucks{\"a}ss, Arno and Neumaier, Felix and Wiesmann, Martin and Clusmann, Hans and Schubert, Gerrit Alexander},
  title     = {Non-invasive assessment of neurovascular coupling after aneurysmal subarachnoid hemorrhage: a prospective observational trial using retinal vessel analysis},
  series = {Frontiers in Neurology},
  volume    = {12},
  journal   = {Frontiers in Neurology},
  number    = {12},
  issn      = {1664-2295},
  doi       = {10.3389/fneur.2021.690183},
  pages     = {1 -- 15},
  year      = {2021},
  abstract  = {Delayed cerebral ischemia (DCI) is a common complication after aneurysmal subarachnoid hemorrhage (aSAH) and can lead to infarction and poor clinical outcome. The underlying mechanisms are still incompletely understood, but animal models indicate that vasoactive metabolites and inflammatory cytokines produced within the subarachnoid space may progressively impair and partially invert neurovascular coupling (NVC) in the brain. Because cerebral and retinal microvasculature are governed by comparable regulatory mechanisms and may be connected by perivascular pathways, retinal vascular changes are increasingly recognized as a potential surrogate for altered NVC in the brain. Here, we used non-invasive retinal vessel analysis (RVA) to assess microvascular function in aSAH patients at different times after the ictus.},
  language  = {en}
}
@incollection{Kotliar2021,
  author    = {Kotliar, Konstantin},
  title     = {Ocular rigidity: clinical approach},
  series = {Ocular Rigidity, Biomechanics and Hydrodynamics of the Eye},
  booktitle = {Ocular Rigidity, Biomechanics and Hydrodynamics of the Eye},
  editor    = {Pallikaris, I. and Tsilimbaris, M. K. and Dastiridou, A. I.},
  publisher = {Springer},
  address   = {Cham},
  isbn      = {978-3-030-64422-2},
  doi       = {10.1007/978-3-030-64422-2_2},
  pages     = {15 -- 43},
  year      = {2021},
  abstract  = {The term ocular rigidity is widely used in clinical ophthalmology. Generally it is assumed as a resistance of the whole eyeball to mechanical deformation and relates to biomechanical properties of the eye and its tissues. Basic principles and formulas for clinical tonometry, tonography and pulsatile ocular blood flow measurements are based on the concept of ocular rigidity. There is evidence for altered ocular rigidity in aging, in several eye diseases and after eye surgery. Unfortunately, there is no consensual view on ocular rigidity: it used to make a quite different sense for different people but still the same name. Foremost there is no clear consent between biomechanical engineers and ophthalmologists on the concept. Moreover ocular rigidity is occasionally characterized using various parameters with their different physical dimensions. In contrast to engineering approach, clinical approach to ocular rigidity claims to characterize the total mechanical response of the eyeball to its deformation without any detailed considerations on eye morphology or material properties of its tissues. Further to the previous chapter this section aims to describe clinical approach to ocular rigidity from the perspective of an engineer in an attempt to straighten out this concept, to show its advantages, disadvantages and various applications.},
  language  = {en}
}
@article{NeumaierKotliarHaerenetal.2021,
  author    = {Neumaier, Felix and Kotliar, Konstantin and Haeren, Roel Hubert Louis and Temel, Yasin and L{\"u}ke, Jan Niklas and Seyam, Osama and Lindauer, Ute and Clusmann, Hans and Hescheler, J{\"u}rgen and Schubert, Gerrit Alexander and Schneider, Toni and Albanna, Walid},
  title     = {Retinal Vessel Responses to Flicker Stimulation Are Impaired in Ca v 2.3-Deficient Mice—An in- vivo Evaluation Using Retinal Vessel Analysis (RVA)},
  series = {Frontiers in Neurology},
  volume    = {12},
  journal   = {Frontiers in Neurology},
  publisher = {Frontiers},
  doi       = {10.3389/fneur.2021.659890},
  pages     = {1 -- 11},
  year      = {2021},
  language  = {en}
}
@article{FiedlerOrzadaFloeseretal.2021,
  author    = {Fiedler, Thomas M. and Orzada, Stephan and Fl{\"o}ser, Martina and Rietsch, Stefan H. G. and Quick, Harald H. and Ladd, Mark E. and Bitz, Andreas},
  title     = {Performance analysis of integrated RF microstrip transmit antenna arrays with high channel count for body imaging at 7 T},
  series = {NMR in Biomedicine},
  volume    = {34},
  journal   = {NMR in Biomedicine},
  number    = {7},
  publisher = {Wiley},
  address   = {Weinheim},
  issn      = {0952-3480 (ISSN)},
  doi       = {10.1002/nbm.4515},
  pages     = {18 SeitenWiley},
  year      = {2021},
  abstract  = {The aim of the current study was to investigate the performance of integrated RF transmit arrays with high channel count consisting of meander microstrip antennas for body imaging at 7 T and to optimize the position and number of transmit ele- ments. RF simulations using multiring antenna arrays placed behind the bore liner were performed for realistic exposure conditions for body imaging. Simulations were performed for arrays with as few as eight elements and for arrays with high channel counts of up to 48 elements. The B1+ field was evaluated regarding the degrees of freedom for RF shimming in the abdomen. Worst-case specific absorption rate (SARwc ), SAR overestimation in the matrix compression, the number of virtual obser- vation points (VOPs) and SAR efficiency were evaluated. Constrained RF shimming was performed in differently oriented regions of interest in the body, and the devia- tion from a target B1+ field was evaluated. Results show that integrated multiring arrays are able to generate homogeneous B1+ field distributions for large FOVs, espe- cially for coronal/sagittal slices, and thus enable body imaging at 7 T with a clinical workflow; however, a low duty cycle or a high SAR is required to achieve homoge- neous B1+ distributions and to exploit the full potential. In conclusion, integrated arrays allow for high element counts that have high degrees of freedom for the pulse optimization but also produce high SARwc , which reduces the SAR accuracy in the VOP compression for low-SAR protocols, leading to a potential reduction in array performance. Smaller SAR overestimations can increase SAR accuracy, but lead to a high number of VOPs, which increases the computational cost for VOP evaluation and makes online SAR monitoring or pulse optimization challenging. Arrays with interleaved rings showed the best results in the study.},
  language  = {en}
}
@article{TemizArtmannKurulgandemirciFıratetal.2021,
  author    = {Temiz Artmann, Ayseg{\"u}l and Kurulgan demirci, Eylem and F{\i}rat, Ipek Seda and Oflaz, Hakan and Artmann, Gerhard},
  title     = {Recombinant activated protein C (rhAPC) affects lipopolysaccharide-induced mechanical compliance changes and beat frequency of mESC-derived cardiomyocyte monolayers},
  series = {SHOCK},
  journal   = {SHOCK},
  publisher = {Wolters Kluwer},
  address   = {K{\"o}ln},
  issn      = {1540-0514},
  doi       = {10.1097/SHK.0000000000001845},
  year      = {2021},
  language  = {en}
}
@inproceedings{ElMoussaouiKassmiAlexopoulosetal.2021,
  author    = {El Moussaoui, Noureddine and Kassmi, Khalil and Alexopoulos, Spiros and Schwarzer, Klemens and Chayeb, Hamid and Bachiri, Najib},
  title     = {Simulation studies on a new innovative design of a hybrid solar distiller MSDH alimented with a thermal and photovoltaic energy},
  series = {Materialstoday: Proceedings},
  volume    = {45},
  booktitle = {Materialstoday: Proceedings},
  number    = {8},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {2214-7853},
  doi       = {10.1016/j.matpr.2021.03.115},
  pages     = {7653 -- 7660},
  year      = {2021},
  abstract  = {In this paper, we present the structure, the simulation the operation of a multi-stage, hybrid solar desalination system (MSDH), powered by thermal and photovoltaic (PV) (MSDH) energy. The MSDH system consists of a lower basin, eight horizontal stages, a field of four flat thermal collectors with a total area of 8.4 m2, 3 Kw PV panels and solar batteries. During the day the system is heated by thermal energy, and at night by heating resistors, powered by solar batteries. These batteries are charged by the photovoltaic panels during the day. More specifically, during the day and at night, we analyse the temperature of the stages and the production of distilled water according to the solar irradiation intensity and the electric heating power, supplied by the solar batteries. The simulations were carried out in the meteorological conditions of the winter month (February 2020), presenting intensities of irradiance and ambient temperature reaching 824 W/m2 and 23 °C respectively. The results obtained show that during the day the system is heated by the thermal collectors, the temperature of the stages and the quantity of water produced reach 80 °C and 30 Kg respectively. At night, from 6p.m. the system is heated by the electric energy stored in the batteries, the temperature of the stages and the quantity of water produced reach respectively 90 °C and 104 Kg for an electric heating power of 2 Kw. Moreover, when the electric power varies from 1 Kw to 3 Kw the quantity of water produced varies from 92 Kg to 134 Kg. The analysis of these results and their comparison with conventional solar thermal desalination systems shows a clear improvement both in the heating of the stages, by 10\%, and in the quantity of water produced by a factor of 3.},
  language  = {en}
}
@article{DickhoffHorikawaFunke2021,
  author    = {Dickhoff, Jens and Horikawa, Atsushi and Funke, Harald},
  title     = {Hydrogen Combustion - new DLE Combustor Addresses NOx Emissions and Flashback},
  series = {Turbomachinery international : the global journal of energy equipment},
  volume    = {62},
  journal   = {Turbomachinery international : the global journal of energy equipment},
  number    = {4},
  publisher = {MJH Life Sciences},
  address   = {Cranbury},
  issn      = {2767-2328},
  pages     = {26 -- 27},
  year      = {2021},
  language  = {en}
}
@incollection{ButenwegGellertMeyer2021,
  author    = {Butenweg, Christoph and Gellert, Christoph and Meyer, Udo},
  title     = {Erdbebenbemessung bei Mauerwerksbauten},
  series = {Mauerwerk Kalender 2021: Kunststoffverankerungen Digitalisierung im Mauerwerksbau},
  booktitle = {Mauerwerk Kalender 2021: Kunststoffverankerungen Digitalisierung im Mauerwerksbau},
  publisher = {Ernst \& Sohn},
  address   = {Berlin},
  isbn      = {9783433032930},
  doi       = {10.1002/9783433610732.ch12},
  pages     = {329 -- 355},
  year      = {2021},
  abstract  = {Der vorliegende Beitrag stellt den seismischen Nachweis von Mauerwerksbauten in Deutschland auf Grundlage der DIN EN 1998-1/NA vor, wobei auch die wesentlichen {\"A}nderungen zu der Norm DIN 4149 vergleichend erl{\"a}utert werden. Vorgestellt werden die Definition der Erdbebeneinwirkung, das seismische Verhalten von Mauerwerksbauten und die Erl{\"a}uterung der Rechenverfahren. Darauf aufbauend wird die Anwendung an drei Praxisbeispielen demonstriert.},
  language  = {de}
}
@incollection{DiekmannEggert2021,
  author    = {Diekmann, Julian and Eggert, Mathias},
  title     = {Is a Progressive Web App an Alternative for Native App Development?},
  series = {3. Wissenschaftsforum: Digitale Transformation (WiFo21) (Lecture Notes in Informatics ; P-319)},
  booktitle = {3. Wissenschaftsforum: Digitale Transformation (WiFo21) (Lecture Notes in Informatics ; P-319)},
  publisher = {Gesellschaft f{\"u}r Informatik},
  address   = {Darmstadt},
  isbn      = {978-3-88579-713-5},
  pages     = {35 -- 48},
  year      = {2021},
  abstract  = {The existence of several mobile operating systems, such as Android and iOS, is a challenge for developers because the individual platforms are not compatible with each other and require separate app developments. For this reason, cross-platform approaches have become popular but lack in cloning the native behavior of the different operating systems. Out of the plenty cross-platform approaches, the progressive web app (PWA) approach is perceived as promising but needs further investigation. Therefore, the paper at hand aims at investigating whether PWAs are a suitable alternative for native apps by developing a PWA clone of an existing app. Two surveys are conducted in which potential users test and evaluate the PWA prototype with regard to its usability. The survey results indicate that PWAs have great potential, but cannot be treated as a general alternative to native apps. For guiding developers when and how to use PWAs, four design guidelines for the development of PWA-based apps are derived based on the results.},
  language  = {en}
}
@article{ButenwegKubalskiElDeibetal.2021,
  author    = {Butenweg, Christoph and Kubalski, Thomas and El-Deib, Khaled and Gellert, Christoph},
  title     = {Erdbebennachweis von Mauerwerksbauten nach DIN EN 1998-1/NA-2021},
  series = {Bautechnik : Zeitschrift f{\"u}r den gesamten Ingenieurbau},
  volume    = {98},
  journal   = {Bautechnik : Zeitschrift f{\"u}r den gesamten Ingenieurbau},
  number    = {11},
  editor    = {Jesse, Dirk},
  publisher = {Ernst \& Sohn},
  address   = {Berlin},
  issn      = {1437-0999},
  doi       = {10.1002/bate.202100064},
  pages     = {852 -- 863},
  year      = {2021},
  abstract  = {Mauerwerksbauten in Deutschland sind mit Einf{\"u}hrung des nationalen Anwendungsdokuments DIN EN 1998-1/NA auf Grundlage einer neuen probabilistischen Erdbebenkarte nachzuweisen. F{\"u}r erfolgreiche Erdbebennachweise {\"u}blicher Grundrissformen von Mauerwerksbauten stehen in dem zuk{\"u}nftigen Anwendungsdokument neue rechnerische Nachweism{\"o}glichkeiten zur Verf{\"u}gung, mit denen die Tragf{\"a}higkeitsreserven von Mauerwerksbauten in der Baupraxis mit einem {\"u}berschaubaren Aufwand besser in Ansatz gebracht werden k{\"o}nnen. Das Standardrechenverfahren ist weiterhin der kraftbasierte Nachweis, der nun mit h{\"o}heren Verhaltensbeiwerten im Vergleich zur DIN 4149 durchgef{\"u}hrt werden kann. Die h{\"o}heren Verhaltensbeiwerte basieren auf der besseren Ausnutzung der geb{\"a}udespezifischen Verformungsf{\"a}higkeit und Energiedissipation sowie der Lastumverteilung der Schubkr{\"a}fte im Grundriss mit Ansatz von Rahmentragwirkung durch Wand-Deckeninteraktionen. Alternativ dazu kann ein nichtlinearer Nachweis auf Grundlage von Pushover-Analysen zur Anwendung kommen. Vervollst{\"a}ndigt werden die Regelungen f{\"u}r Mauerwerksbauten durch neue Regelungen f{\"u}r nichttragende Innenw{\"a}nde und Außenmauerschalen. Der vorliegende Beitrag stellt die Grundlagen und Hintergr{\"u}nde der neuen rechnerischen Nachweise in DIN EN 1998-1/NA vor und demonstriert deren Anwendung an einem Beispiel aus der Praxis.},
  language  = {de}
}
@article{OertelBung2021,
  author    = {Oertel, Mario and Bung, Daniel Bernhard},
  title     = {Hochwasserschutz - eine Aufgabe f{\"u}r eine nachhaltige Wasserwirtschaft},
  series = {Wasserwirtschaft},
  volume    = {111},
  journal   = {Wasserwirtschaft},
  number    = {9-10},
  publisher = {Springer Vieweg},
  address   = {Wiesbaden},
  issn      = {0043-0978},
  pages     = {3 -- 19},
  year      = {2021},
  language  = {de}
}
@inproceedings{Butenweg2021,
  author    = {Butenweg, Christoph},
  title     = {Integrated approach for monitoring and management of buildings with digital building models and modern sensor technologies},
  series = {Proceedings of the International Conference Civil Engineering 2021 - Achievements and Visions},
  booktitle = {Proceedings of the International Conference Civil Engineering 2021 - Achievements and Visions},
  editor    = {Kuzmanović, Vladan and Ignjatović, Ivan},
  publisher = {University of Belgrade},
  address   = {Belgrade},
  pages     = {67 -- 75},
  year      = {2021},
  abstract  = {Nowadays modern high-performance buildings and facilities are equipped with monitoring systems and sensors to control building characteristics like energy consumption, temperature pattern and structural safety. The visualization and interpretation of sensor data is typically based on simple spreadsheets and non-standardized user-oriented solutions, which makes it difficult for building owners, facility managers and decision-makers to evaluate and understand the data. The solution of this problem in the future are integrated BIM-Sensor approaches which allow the generation of BIM models incorporating all relevant information of monitoring systems. These approaches support both the dynamic visualization of key structural performance parameters, the effective long-term management of sensor data based on BIM and provide a user-friendly interface to communicate with various stakeholders. A major benefit for the end user is the use of the BIM software architecture, which is the future standard anyway. In the following, the application of the integrated BIM-Sensor approach is illustrated for a typical industrial facility as a part of an early warning and rapid response system for earthquake events currently developed in the research project "ROBUST" with financial support by the German Federal Ministry for Economic Affairs and Energy (BMWI).},
  language  = {en}
}
@article{SeefeldtDachwald2021,
  author    = {Seefeldt, Patric and Dachwald, Bernd},
  title     = {Temperature increase on folded solar sail membranes},
  series = {Advances in Space Research},
  volume    = {67},
  journal   = {Advances in Space Research},
  number    = {9},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0273-1177},
  doi       = {10.1016/j.asr.2020.09.026},
  pages     = {2688 -- 2695},
  year      = {2021},
  language  = {en}
}