@article{PoghossianWernerBuniatyanetal.2017, author = {Poghossian, Arshak and Werner, Frederik and Buniatyan, V. V. and Wagner, Torsten and Miamoto, K. and Yoshinobu, T. and Sch{\"o}ning, Michael Josef}, title = {Towards addressability of light-addressable potentiometric sensors: Shunting effect of non-illuminated region and cross-talk}, series = {Sensor and Actuators B: Chemical}, journal = {Sensor and Actuators B: Chemical}, number = {244}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0925-4005}, doi = {10.1016/j.snb.2017.01.047}, pages = {1071 -- 1079}, year = {2017}, abstract = {The LAPS (light-addressable potentiometric sensor) platform is one of the most attractive approaches for chemical and biological sensing with many applications ranging from pH and ion/analyte concentration measurements up to cell metabolism detection and chemical imaging. However, although it is generally accepted that LAPS measurements are spatially resolved, the light-addressability feature of LAPS devices has not been discussed in detail so far. In this work, an extended electrical equivalent-circuit model of the LAPS has been presented, which takes into account possible cross-talk effects due to the capacitive coupling of the non-illuminated region. A shunting effect of the non-illuminated area on the measured photocurrent and addressability of LAPS devices has been studied. It has been shown, that the measured photocurrent will be determined not only by the local interfacial potential in the illuminated region but also by possible interfacial potential changes in the non-illuminated region, yielding cross-talk effects. These findings were supported by the experimental investigations of a penicillin-sensitive multi-spot LAPS and a metal-insulator-semiconductor LAPS as model systems.}, language = {en} } @article{PoghossianYoshinobuSimonisetal.2000, author = {Poghossian, Arshak and Yoshinobu, T. and Simonis, A. and Ecken, H. and L{\"u}th, H. and Sch{\"o}ning, Michael Josef}, title = {Penicillin detection by means of field-effect based sensors: EnFET, capacitive EIS sensor or LAPS?}, series = {Proceedings : Copenhagen, Denmark, 27 - 30 August 2000 / [ed.: R. de Reus ...]}, journal = {Proceedings : Copenhagen, Denmark, 27 - 30 August 2000 / [ed.: R. de Reus ...]}, publisher = {MIC, Mikroelektronik Centret}, address = {Lyngby, Denmark}, isbn = {87-89935-50-0}, pages = {27 -- 30}, year = {2000}, language = {en} } @article{PoghossianYoshinobuSchoening2003, author = {Poghossian, Arshak and Yoshinobu, Tatsuo and Sch{\"o}ning, Michael Josef}, title = {Flow-velocity microsensors based on semiconductor field-effect structures}, series = {Sensors. 3 (2003), H. 7}, journal = {Sensors. 3 (2003), H. 7}, isbn = {1424-8220}, pages = {202 -- 212}, year = {2003}, language = {en} } @article{PoghossianYoshinobuSimonisetal.2001, author = {Poghossian, Arshak and Yoshinobu, Tatsuo and Simonis, A. and Ecken, H. and L{\"u}th, Hans and Sch{\"o}ning, Michael Josef}, title = {Penicillin detection by means of field-effect based sensors: EnFET, capacitive EIS sensor or LAPS?}, series = {Sensors and Actuators B. 78 (2001), H. 1-3}, journal = {Sensors and Actuators B. 78 (2001), H. 1-3}, isbn = {0925-4005}, pages = {237 -- 242}, year = {2001}, language = {en} } @article{PogorelovaRogachevAkimbekovetal.2024, author = {Pogorelova, Natalia and Rogachev, Evgeniy and Akimbekov, Nuraly S. and Digel, Ilya}, title = {Effect of dehydration method on the micro- and nanomorphological properties of bacterial cellulose produced by Medusomyces gisevii on different substrates}, series = {Journal of materials science}, volume = {2024}, journal = {Journal of materials science}, publisher = {Springer Science + Business Media}, address = {Dordrecht}, issn = {1573-4803 (Online)}, doi = {10.1007/s10853-024-09596-3}, pages = {13 Seiten}, year = {2024}, abstract = {Many important properties of bacterial cellulose (BC), such as moisture absorption capacity, elasticity and tensile strength, largely depend on its structure. This paper presents a study on the effect of the drying method on BC films produced by Medusomyces gisevii using two different procedures: room temperature drying (RT, (24 ± 2 °C, humidity 65 ± 1\%, dried until a constant weight was reached) and freeze-drying (FD, treated at - 75 °C for 48 h). BC was synthesized using one of two different carbon sources—either glucose or sucrose. Structural differences in the obtained BC films were evaluated using atomic force microscopy (AFM), scanning electron microscopy (SEM), and X-ray diffraction. Macroscopically, the RT samples appeared semi-transparent and smooth, whereas the FD group exhibited an opaque white color and sponge-like structure. SEM examination showed denser packing of fibrils in FD samples while RT-samples displayed smaller average fiber diameter, lower surface roughness and less porosity. AFM confirmed the SEM observations and showed that the FD material exhibited a more branched structure and a higher surface roughness. The samples cultivated in a glucose-containing nutrient medium, generally displayed a straight and ordered shape of fibrils compared to the sucrose-derived BC, characterized by a rougher and wavier structure. The BC films dried under different conditions showed distinctly different crystallinity degrees, whereas the carbon source in the culture medium was found to have a relatively small effect on the BC crystallinity.}, language = {en} } @article{PogorelovaRogachevDigeletal.2020, author = {Pogorelova, Natalia and Rogachev, Evgeniy and Digel, Ilya and Chernigova, Svetlana and Nardin, Dmitry}, title = {Bacterial Cellulose Nanocomposites: Morphology and Mechanical Properties}, series = {Materials}, volume = {13}, journal = {Materials}, number = {12}, publisher = {MDPI}, address = {Basel}, isbn = {1996-1944}, doi = {10.3390/ma13122849}, pages = {1 -- 16}, year = {2020}, abstract = {Bacterial cellulose (BC) is a promising material for biomedical applications due to its unique properties such as high mechanical strength and biocompatibility. This article describes the microbiological synthesis, modification, and characterization of the obtained BC-nanocomposites originating from symbiotic consortium Medusomyces gisevii. Two BC-modifications have been obtained: BC-Ag and BC-calcium phosphate (BC-Ca3(PO4)2). Structure and physicochemical properties of the BC and its modifications were investigated by scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDX), atomic force microscopy (AFM), and infrared Fourier spectroscopy as well as by measurements of mechanical and water holding/absorbing capacities. Topographic analysis of the surface revealed multicomponent thick fibrils (150-160 nm in diameter and about 15 µm in length) constituted by 50-60 nm nanofibrils weaved into a left-hand helix. Distinctive features of Ca-phosphate-modified BC samples were (a) the presence of 500-700 nm entanglements and (b) inclusions of Ca3(PO4)2 crystals. The samples impregnated with Ag nanoparticles exhibited numerous roundish inclusions, about 110 nm in diameter. The boundaries between the organic and inorganic phases were very distinct in both cases. The Ag-modified samples also showed a prominent waving pattern in the packing of nanofibrils. The obtained BC gel films possessed water-holding capacity of about 62.35 g/g. However, the dried (to a constant mass) BC-films later exhibited a low water absorption capacity (3.82 g/g). It was found that decellularized BC samples had 2.4 times larger Young's modulus and 2.2 times greater tensile strength as compared to dehydrated native BC films. We presume that this was caused by molecular compaction of the BC structure.}, language = {en} } @article{PohlSiegertMeschetal.1998, author = {Pohl, Martina and Siegert, Petra and Mesch, K. and Bruhn, H. and Gr{\"o}tzinger, Joachim}, title = {Active site mutants of pyruvate decarboxylase from Zymomonas mobilis : a site-directed mutagenesis study of L112, I472, I476, E473 and N482}, series = {European journal of biochemistry}, volume = {Vol. 257}, journal = {European journal of biochemistry}, number = {Iss. 3}, issn = {1432-1033 (E-Journal); 1742-4658 (E-Journal); 0014-2956 (Print); 1742-464X (Print)}, pages = {538 -- 546}, year = {1998}, language = {en} } @inproceedings{PohleFroehlichDalitzRichteretal.2020, author = {Pohle-Fr{\"o}hlich, Regina and Dalitz, Christoph and Richter, Charlotte and Hahnen, Tobias and St{\"a}udle, Benjamin and Albracht, Kirsten}, title = {Estimation of muscle fascicle orientation in ultrasonic images}, series = {Proceedings of the 15th International Joint Conference on Computer Vision, Imaging and Computer Graphics Theory and Applications - Volume 5}, booktitle = {Proceedings of the 15th International Joint Conference on Computer Vision, Imaging and Computer Graphics Theory and Applications - Volume 5}, publisher = {SciTePress}, address = {Set{\´u}bal, Portugal}, isbn = {978-989-758-402-2}, doi = {10.5220/0008933900790086}, pages = {79 -- 86}, year = {2020}, abstract = {We compare four different algorithms for automatically estimating the muscle fascicle angle from ultrasonic images: the vesselness filter, the Radon transform, the projection profile method and the gray level cooccurence matrix (GLCM). The algorithm results are compared to ground truth data generated by three different experts on 425 image frames from two videos recorded during different types of motion. The best agreement with the ground truth data was achieved by a combination of pre-processing with a vesselness filter and measuring the angle with the projection profile method. The robustness of the estimation is increased by applying the algorithms to subregions with high gradients and performing a LOESS fit through these estimates.}, language = {en} } @misc{Polaczek1983, author = {Polaczek, Christa}, title = {Kofaser - Kategorien und differentielle Algebren}, publisher = {Math. Inst. der Univ.}, address = {Bonn}, pages = {178 S. : Anh.}, year = {1983}, language = {de} } @phdthesis{Polaczek1995, author = {Polaczek, Christa}, title = {Automatische 3-dimensionale FEM-Netzgenerierung f{\"u}r die Formf{\"u}ll- und Erstarrungssimulation. - (Fortschrittberichte VDI : Reihe 20, Rechnerunterst{\"u}tzte Verfahren ; 182)}, number = {Als Ms. gedr.}, publisher = {VDI-Verl.}, address = {D{\"u}sseldorf}, isbn = {3-18-318220-3}, pages = {VII, 131 S. : Ill., graph. Darst.}, year = {1995}, language = {de} } @article{PolaczekHenn2008, author = {Polaczek, Christa and Henn, Gudrun}, title = {Gute Vorkenntnisse verk{\"u}rzen die Studienzeit}, series = {Mathematikinformation : eine Zeitschrift von Begabtenf{\"o}rderung Mathematik e.V.}, volume = {2008}, journal = {Mathematikinformation : eine Zeitschrift von Begabtenf{\"o}rderung Mathematik e.V.}, number = {49}, publisher = {Begabtenf{\"o}rderung Mathematik}, address = {Neubiberg}, issn = {1612-9156}, pages = {46 -- 50}, year = {2008}, language = {de} } @article{PolenKraemerBongaertsetal.2005, author = {Polen, T. and Kr{\"a}mer, Marco and Bongaerts, Johannes and Wubbolts, Marcel and Wendisch, V. F.}, title = {The global gene expression response of Escherichia coli to L-phenylalanine}, series = {Journal of biotechnology}, volume = {Vol. 115}, journal = {Journal of biotechnology}, number = {Iss. 3}, issn = {1873-4863 (E-Journal); 0168-1656 (Print)}, pages = {221 -- 237}, year = {2005}, language = {en} } @book{Polumsky1987, author = {Polumsky, Dieter}, title = {Erweiterungsm{\"o}glichkeiten des Verkehrsplanungsalgorithmus}, publisher = {Inst. f{\"u}r Stadtbauwesen, RWTH}, address = {Aachen}, isbn = {3-88354-114-1}, pages = {X, 200 S. : graph. Darst., Kt.}, year = {1987}, language = {de} } @book{Polumsky2001, author = {Polumsky, Dieter}, title = {Hinweise auf Verfahren bei Verkehrsplanungen im Personenverkehr / Forschungsgesellschaft f{\"u}r Straßen- und Verkehrswesen, Arbeitsgruppe Verkehrsplanung. [Arbeitsgruppe Verkehrsplanung, Arbeitsausschuss: Erhebung und Voraussch{\"a}tzung des Verkehrs, Arbeitskre}, publisher = {FGSV-Verl.}, address = {K{\"o}ln}, pages = {27 S. : graph. Darst.}, year = {2001}, language = {de} } @book{Polumsky1988, author = {Polumsky, Dieter}, title = {Zusammenschau der modelltechnischen Erweiterungsm{\"o}glichkeiten des Algorithmus der Verkehrsplanung : insbesondere unter dem Aspekt der Bindungen durch Haushalt und Familie}, pages = {X, 200 S.}, year = {1988}, language = {de} } @article{Polumsky2001, author = {Polumsky, Dieter}, title = {Kann man Verkehrsplanung verst{\"a}ndlich machen?}, series = {Straßenverkehrstechnik. 45 (2001), H. 6}, journal = {Straßenverkehrstechnik. 45 (2001), H. 6}, isbn = {0039-2219}, pages = {287 -- 293}, year = {2001}, language = {de} } @book{Polumsky1978, author = {Polumsky, Dieter}, title = {Ordnende, verkehrsregelnde und bauliche Elemente f{\"u}r den Einsatz zur Verkehrsberuhigung in Wohngebieten. Planungsheft. Baier, Reinhold [Bearb.] ... Polumsky, Dieter [Bearb.] TH Aachen, Institut f{\"u}r Stadtbauwesen (Hrsg.)}, publisher = {Selbstverlag}, address = {Aachen}, pages = {143 S.}, year = {1978}, language = {de} } @article{Polumsky1981, author = {Polumsky, Dieter}, title = {Pr{\"a}missen und Methoden bei großr{\"a}umigen Verkehrsprognosen}, publisher = {Inst.}, address = {Aachen}, pages = {67 -- 75}, year = {1981}, language = {de} } @book{Polumsky1976, author = {Polumsky, Dieter}, title = {Zentralit{\"a}tsaspekte im regionalen Reiseverhalten : M{\"o}glichkeiten zur Differenzierung der Modelle f{\"u}r Verkehrserzeugung und Verkehrsverteilung}, publisher = {Selbstverl. am Inst. f{\"u}r Stadtbauwesen, RWTH}, address = {Aachen}, pages = {XVII, 279 S. : graph. Darst., Kt.}, year = {1976}, language = {de} } @book{Polumsky1986, author = {Polumsky, Dieter}, title = {Dynamisierung von Verkehrsumlegungsmodellen / Projektleiter: D. Polumsky}, publisher = {Inst. f{\"u}r Stadtbauwesen, RWTH}, address = {Aachen}, isbn = {3-88354-111-7}, pages = {III, 145 S. : {\"u}berwiegend graph. Darst., Kt.}, year = {1986}, language = {de} } @article{Polumsky1979, author = {Polumsky, Dieter}, title = {DIVA - Datenbankorientierter - Interaktiver - Verkehrs-Algorithmus / M{\"a}cke, Paul A. [Hrsg.]}, publisher = {Inst.}, address = {Aachen}, isbn = {3-88354-076-5}, pages = {77 -- 95}, year = {1979}, language = {de} } @book{Polumsky1977, author = {Polumsky, Dieter}, title = {Analyse und Prognose des G{\"u}terverkehrs im Raum Mittelrhein / Rothschuh, Bruno [Mitarb.] ... Polumsky, Dieter [Mitarb.]}, publisher = {Selbstverl.}, address = {Aachen}, isbn = {3-88354-057-9}, pages = {ca. 260 S.}, year = {1977}, language = {de} } @article{PolumskyEckelmann1984, author = {Polumsky, Dieter and Eckelmann, Marion}, title = {Zentralit{\"a}tsgef{\"u}ge der Raumordnung in Abh{\"a}ngigkeit von Erreichbarkeiten}, series = {Stadt und Gemeinde. 39 (1984), H. 10}, journal = {Stadt und Gemeinde. 39 (1984), H. 10}, isbn = {0342-7706}, pages = {493 -- 496}, year = {1984}, language = {de} } @book{PolumskyEckelmannRatsch1985, author = {Polumsky, Dieter and Eckelmann, Marion and Ratsch, Birgit}, title = {Das Zentralit{\"a}tsgef{\"u}ge der Raumordnung in Abh{\"a}ngigkeit von Erreichbarkeiten / Bearb.: Marion Eckelmann ; Dieter Polumsky ; Birgit Ratsch}, publisher = {Inst. f{\"u}r Stadtbauwesen, RWTH}, address = {Aachen}, isbn = {3-88354-110-9}, pages = {222 S. : zahlr. graph. Darst., Kt.}, year = {1985}, language = {de} } @book{PolumskyKampermann1979, author = {Polumsky, Dieter and Kampermann, L.}, title = {Begriffe und Symbole : Erl{\"a}uterungen zur Fachsprache der Verkehrsplaner / D. Polumsky ; L. Kampermann}, publisher = {Selbstverl. am Inst. f{\"u}r Stadtbauwesen, RWTH}, address = {Aachen}, isbn = {3-88354-074-9}, pages = {83 S.}, year = {1979}, language = {de} } @article{PolumskyKirsch1984, author = {Polumsky, Dieter and Kirsch, Helmut}, title = {Entscheidungsfindung f{\"u}r oder gegen Verkehrsverlagerungen / Kirsch, Helmut; Polumsky, Dieter}, series = {Der St{\"a}dtetag. 37 (1984), H. 6}, journal = {Der St{\"a}dtetag. 37 (1984), H. 6}, isbn = {0038-9048}, pages = {417 -- 427}, year = {1984}, language = {de} } @article{PolumskyKirsch1983, author = {Polumsky, Dieter and Kirsch, Helmut}, title = {Fl{\"a}chenhafte Verkehrsberuhigung / Kirsch, Helmut; Polumsky, Dieter}, series = {Der St{\"a}dtetag. 36 (1983), H. 8}, journal = {Der St{\"a}dtetag. 36 (1983), H. 8}, isbn = {0038-9048}, pages = {552 -- 560}, year = {1983}, language = {de} } @book{PolumskyMaecke1978, author = {Polumsky, Dieter and M{\"a}cke, Paul A.}, title = {Einfluß der Zentralit{\"a}t eines Ortes auf Verkehrserzeugung und Verkehrsverteilung / P. A. M{\"a}cke ; Dieter Polumsky}, publisher = {Bundesminister f{\"u}r Verkehr, Abt. Straßenbau}, address = {Bonn- Bad Godesberg}, pages = {132 S. : zahlr. graph. Darst., Kt.}, year = {1978}, language = {de} } @article{PolzinLindemann1999, author = {Polzin, Dietmar W. and Lindemann, Markus}, title = {Evolution elektronischer M{\"a}rkte in G{\"u}terverkehr und Logistik}, series = {Wirtschaftsinformatik. Vol. 41 (1999), iss. 6}, journal = {Wirtschaftsinformatik. Vol. 41 (1999), iss. 6}, issn = {0937-6429}, pages = {526 -- 537}, year = {1999}, language = {de} } @inproceedings{PompSchwarzboezlKolletal.2010, author = {Pomp, Stefan and Schwarzb{\"o}zl, Peter and Koll, Gerrit and Hennecke, Klaus and Schmitz, Mark and Hoffschmidt, Bernhard}, title = {Advanced concept for a solar thermal power plant with open volumetric air receiver}, series = {SolarPACES 2010 : the CSP Conference: electricity, fuels and clean water from concentrated solar energy ; 21 to 24 September 2010, Perpignan, France}, booktitle = {SolarPACES 2010 : the CSP Conference: electricity, fuels and clean water from concentrated solar energy ; 21 to 24 September 2010, Perpignan, France}, publisher = {Soc. OSC}, address = {Saint Maur}, pages = {97 -- 98}, year = {2010}, language = {en} } @article{PookhalilAmoabedinyTabeshetal.2016, author = {Pookhalil, Ali and Amoabediny, Ghassem and Tabesh, Hadi and Behbahani, Mehdi and Mottaghy, Khosrow}, title = {A new approach for semiempirical modeling of mechanical blood trauma}, series = {The international journal of artificial organs}, volume = {39}, journal = {The international journal of artificial organs}, number = {4}, publisher = {Sage}, address = {London}, issn = {1724-6040}, doi = {10.5301/ijao.5000474}, pages = {171 -- 177}, year = {2016}, abstract = {Purpose Two semi-empirical models were recently published, both making use of existing literature data, but each taking into account different physical phenomena that trigger hemolysis. In the first model, hemoglobin (Hb) release is described as a permeation procedure across the membrane, assuming a shear stress-dependent process (sublethal model). The second model only accounts for hemoglobin release that is caused by cell membrane breakdown, which occurs when red blood cells (RBC) undergo mechanically induced shearing for a period longer than the threshold time (nonuniform threshold model). In this paper, we introduce a model that considers the hemolysis generated by both these possible phenomena. Methods Since hemolysis can possibly be caused by permeation of hemoglobin through the RBC functional membrane as well as by release of hemoglobin from RBC membrane breakdown, our proposed model combines both these models. An experimental setup consisting of a Couette device was utilized for validation of our proposed model. Results A comparison is presented between the damage index (DI) predicted by the proposed model vs. the sublethal model vs. the nonthreshold model and experimental datasets. This comparison covers a wide range of shear stress for both human and porcine blood. An appropriate agreement between the measured DI and the DI predicted by the present model was obtained. Conclusions The semiempirical hemolysis model introduced in this paper aims for significantly enhanced conformity with experimental data. Two phenomenological outcomes become possible with the proposed approach: an estimation of the average time after which cell membrane breakdown occurs under the applied conditions, and a prediction of the ratio between the phenomena involved in hemolysis.}, language = {en} } @article{PoppelWolf2013, author = {Poppel, Kristin Isabel and Wolf, Martin R.}, title = {M{\"o}glichkeiten und Potentiale von Revisionsmarketing}, series = {Zeitschrift Interne Revision : ZIR ; Fachzeitschrift f{\"u}r Wissenschaft und Praxis}, volume = {48}, journal = {Zeitschrift Interne Revision : ZIR ; Fachzeitschrift f{\"u}r Wissenschaft und Praxis}, number = {4}, publisher = {Erich Schmidt Verlag}, address = {Berlin}, issn = {0044-3816}, pages = {200 -- 208}, year = {2013}, language = {de} } @article{PorschenGartzenGewehretal.1978, author = {Porschen, W. and Gartzen, J. and Gewehr, K. and M{\"u}hlensiepen, H. and Weber, Hans-Joachim and Feinedegen, L E.}, title = {In vivo assay of the radiation sensitivity of hypoxic tumour cells : influence of γ-rays, cyclotron neutrons, misonidazole, hyperthermia and mixed modalities}, series = {The British journal of cancer / Supplement}, journal = {The British journal of cancer / Supplement}, number = {3}, publisher = {Lewis}, address = {London}, issn = {0306-9443}, pages = {194 -- 197}, year = {1978}, abstract = {Tumour cell death can be evaluated in the living mouse by externally measuring the rate of loss of tumour-bound DNA tracer. By sequentially labelling the tumour-bearing animals with ¹²⁵IUdR and ¹³¹IUdR 50 h apart, the average tumour cells at the time of the second injection are labelled by ¹²⁵IUdR and the euoxic tumour cells are specifically labelled with ¹³¹IUdR. Tumour treatment at this stage of labelling permits the observation of the reaction of euoxic cells and average tumour cells and finally yields data on hypoxic cells and thus on the oxygen enhancement ratio. This information adds to results from tumour control and growth delay. With this technique effects were analysed of 60-Co γ-rays, cyclotron neutrons (E = 6 MeV), misonidazole (500 mg/kg body wt) and hyperthermia (42°C water-bath), or combinations of these. Misonidazole (15 min before irradiation) altered the oxygen enhancement ratio by a factor of 1·5 for γ-rays and of 1·1 for neutrons; when evaluated from tumour-growth delay and TCD-50 misonidazole gave a dose modifying factor of 1·47 for γ-rays and of 1·2-1·3 for neutrons. Based on percentage tumour regression 100 days after treatment, the enhancement ratio from hyperthermia (after irradiation) was 2·75 for γ-rays (at 10 Gray) and 2·2 for neutrons (at 3·2 Gray). For neutrons combined with misonidazole and hyperthermia the ratio was 2·4. These results demonstrate that effects of neutron irradiation may be modified by electron-affinic substances and/or hyperthermia.}, language = {en} } @misc{PothMonzonTippkoetteretal.2009, author = {Poth, S. and Monzon, M. and Tippk{\"o}tter, Nils and Ulber, Roland}, title = {Fermentation von Hydrolysaten aus Lignocellulose}, series = {Chemie Ingenieur Technik}, volume = {81}, journal = {Chemie Ingenieur Technik}, number = {8}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {0009-286X}, doi = {10.1002/cite.200950243}, pages = {1220}, year = {2009}, abstract = {Die {\"o}konomische Abh{\"a}ngigkeit von fossilen Brennstoffen und der klimatische Wandel durch die Nutzung dieser haben zu einer intensiven Suche nach erneuerbaren Rohstoffen f{\"u}r die Produktion von Chemikalien und Treibstoffen gef{\"u}hrt. Ein viel versprechender Rohstoff in diesem Zusammenhang sind Zucker, die mittels enzymatischer Hydrolyse aus Lignocellulose gewonnen werden k{\"o}nnen. Die Fermentation erfolgt mit Cellulose- bzw. Hemicellulose-Fraktionen, welche durch thermo-chemische Vorbehandlung von Holz gewonnen und anschließend enzymatisch hydrolysiert werden. Die in den Hydrolysaten enthaltenen Zuckermonomere dienen als Kohlenstoffquelle f{\"u}r die Produktion von Ethanol. Da sowohl Glucose als auch Xylose in den unterschiedlichen Fraktionen enthalten sind, wird zur Umsetzung dieser eine Co-Fermentation zweier Hefen durchgef{\"u}hrt. Im Rahmen der Optimierung dieser Fermentationen werden neben der Erg{\"a}nzung der Hydrolysate durch notwendige Salze auch Verfahrenweisen wie Fed-Batch-Fermentationen untersucht. Ein weiterer interessanter Ansatz, welcher in diesem Rahmen gepr{\"u}ft wird, ist die enzymatische Hydrolyse der Lignocellulose-Fraktionen und die simultane Fermentation der dabei entstehenden Zucker in einem Schritt. Des Weiteren wurde die Eignung der Hydrolysate f{\"u}r die Biomasseproduktion anderer Mikroorganismen wie Escherichia coli getestet.}, language = {de} } @misc{PothMonzonTippkoetteretal.2009, author = {Poth, S. and Monzon, M. and Tippk{\"o}tter, Nils and Ulber, Roland}, title = {Enzymatische Hydrolyse von vorbehandelter Lignocellulose}, series = {Chemie Ingenieur Technik}, volume = {81}, journal = {Chemie Ingenieur Technik}, number = {8}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {0009-286X}, doi = {10.1002/cite.200950244}, pages = {1049}, year = {2009}, abstract = {Die {\"o}konomische Abh{\"a}ngigkeit von fossilen Brennstoffen und der klimatische Wandel durch die Nutzung dieser haben zu einer intensiven Suche nach erneuerbaren Rohstoffen f{\"u}r die Produktion von Chemikalien und Treibstoffen gef{\"u}hrt. Ein viel versprechender Rohstoff in diesem Zusammenhang sind Zucker, die mittels enzymatischer Hydrolyse aus Lignocellulose gewonnen und beispielsweise zu Ethanol umgesetzt werden k{\"o}nnen. Dabei ist es notwendig die Hydrolyse in Hinsicht auf das verwendete Substrat und die Verwendung der entstehenden Hydrolysate f{\"u}r die Fermentation von Alkohol zu optimieren. Als Substrat dienen Cellulose- und Hemicellulose-Fraktionen, die durch thermo-chemische Vorbehandlung von Holz gewonnen werden. Die Vorbehandlung erfolgt bei unserem Projektpartner am Johann Heinrich von Th{\"u}nen Institut in Hamburg. Verschiedene kommerziell erh{\"a}ltliche Enzyme, thermostabile eingeschlossen, wurden auf ihre F{\"a}higkeit hin untersucht, diese Fraktionen zu den entsprechenden Zuckern umsetzen zu k{\"o}nnen. Um die Konzentration an fermentierbaren Zuckern zu steigern werden verschiedene Optimierungen durchgef{\"u}hrt, z. B. die Erh{\"o}hung der Substrat- bzw. Enzymkonzentrationen. Ein weiterer interessanter Ansatz, welcher ebenfalls verfolgt wird, ist es die Hydrolyse und die Fermentation in einem Schritt durchzuf{\"u}hren.}, language = {de} } @misc{PothMonzonTippkoetteretal.2010, author = {Poth, S. and Monzon, M. and Tippk{\"o}tter, Nils and Ulber, Roland}, title = {Lignocellulose-Bioraffinerie: Simultane Verzuckerung und Fermentation}, series = {Chemie Ingenieur Technik}, volume = {82}, journal = {Chemie Ingenieur Technik}, number = {9}, publisher = {Wiley-VCH}, address = {Weinheim}, doi = {10.1002/cite.201050360}, pages = {1568}, year = {2010}, abstract = {Die am h{\"a}ufigsten genutzten Rohstoffe f{\"u}r die Produktion von Treibstoffen und Chemikalien sind fossilen Ursprungs. Da diese limitiert sind, werden im Hinblick auf die Nachhaltigkeit alternative, erneuerbare Rohstoffquellen intensiv untersucht. Vielversprechend in diesem Kontext sind die in Lignocellulose enthaltenen Zucker, die beispielsweise zur Produktion von Ethanol genutzt werden k{\"o}nnen. In der Regel sind f{\"u}r eine Lig-nocellulose-Bioraffinerie mehrere Prozessschritte notwendig: Vorbehandlung, Verzuckerung und Fermentation. Um diesen Prozess einfacher zu gestalten, ist es m{\"o}glich, die Verzuckerung und die Fermentation in einem Schritt durchzuf{\"u}hren (SSF). Als Substrat wird hier Cellulose-Faserstoff verwendet, der durch das Organosolv-Verfahren aufgeschlossen wurde. Die Hydrolyse erfolgt mit kommerziell erh{\"a}ltlichen Enzymen und f{\"u}r die Fermentation zu Ethanol werden zwei Hefen verwendet. Beim SSF-Verfahren konnte, im Vergleich zur entkoppelten Verfahrensweise, trotz bestehender Unterschiede in den Temperatur-Optima von Enzymen und Hefen eine Steigerung in der Ethanol-Ausbeute von 0,15 auf 0,2 gg⁻¹ beobachtet werden. Um wirtschaftliche Ausbeuten und Konzentrationen des Produkts erzielen zu k{\"o}nnen, ist es notwendig den Prozess weiter zu optimieren. Im Einzelfall muss {\"u}berpr{\"u}ft werden, ob diese Verfahrensweise auch f{\"u}r die Produktion anderer interessanter Stoffe (wie Itacons{\"a}ure, Bernsteins{\"a}ure) geeignet ist.}, language = {de} } @article{PothMonzonTippkoetteretal.2011, author = {Poth, Sebastian and Monzon, Magaly and Tippk{\"o}tter, Nils and Ulber, Roland}, title = {Lignocellulosic biorefinery: Process integration of hydrolysis and fermentation (SSF process)}, series = {Holzforschung}, volume = {65}, journal = {Holzforschung}, number = {5}, publisher = {De Gruyter}, address = {Berlin}, pages = {633 -- 637}, year = {2011}, abstract = {The aim of the present work is the process integration and the optimization of the enzymatic hydrolysis of wood and the following fermentation of the products to ethanol. The substrate is a fiber fraction obtained by organosolv pre-treatment of beech wood. For the ethanol production, a co-fermentation by two different yeasts (Saccharomyces cerevisiae and Pachysolen tannophilus) was carried out to convert glucose as well as xylose. Two approaches has been followed: 1. A two step process, in which the hydrolysis of the fiber fraction and the fermentation to product are separated from each other. 2. A process, in which the hydrolysis and the fermentation are carried out in one single process step as simultaneous saccharification and fermentation (SSF). Following the first approach, a yield of about 0.15 g ethanol per gram substrate can be reached. Based on the SSF, one process step can be saved, and additionally, the gained yield can be raised up to 0.3 g ethanol per gram substrate.}, language = {en} } @inproceedings{PothMonzonTippkoetteretal.2010, author = {Poth, Sebastian and Monzon, Magaly and Tippk{\"o}tter, Nils and Ulber, Roland}, title = {Lignocellulosic biorefinery : process integration of hydrolysis and fermentation}, series = {Proceedings / 11th European Workshop on Lignocellulosics and Pulp : August 16 - 19, 2010, Hamburg, Germany}, booktitle = {Proceedings / 11th European Workshop on Lignocellulosics and Pulp : August 16 - 19, 2010, Hamburg, Germany}, publisher = {vTi}, address = {Hamburg}, pages = {65 -- 68}, year = {2010}, language = {en} } @article{PourshahidiAchtsnichtNambipareecheeetal.2021, author = {Pourshahidi, Ali Mohammad and Achtsnicht, Stefan and Nambipareechee, Mrinal Murali and Offenh{\"a}usser, Andreas and Krause, Hans-Joachim}, title = {Multiplex detection of magnetic beads using offset field dependent frequency mixing magnetic detection}, series = {Sensors}, volume = {21}, journal = {Sensors}, number = {17}, publisher = {MDPI}, address = {Basel}, issn = {1424-8220}, doi = {10.3390/s21175859}, pages = {16 Seiten}, year = {2021}, abstract = {Magnetic immunoassays employing Frequency Mixing Magnetic Detection (FMMD) have recently become increasingly popular for quantitative detection of various analytes. Simultaneous analysis of a sample for two or more targets is desirable in order to reduce the sample amount, save consumables, and save time. We show that different types of magnetic beads can be distinguished according to their frequency mixing response to a two-frequency magnetic excitation at different static magnetic offset fields. We recorded the offset field dependent FMMD response of two different particle types at frequencies ƒ₁ + n⋅ƒ₂, n = 1, 2, 3, 4 with ƒ₁ = 30.8 kHz and ƒ₂ = 63 Hz. Their signals were clearly distinguishable by the locations of the extremes and zeros of their responses. Binary mixtures of the two particle types were prepared with different mixing ratios. The mixture samples were analyzed by determining the best linear combination of the two pure constituents that best resembled the measured signals of the mixtures. Using a quadratic programming algorithm, the mixing ratios could be determined with an accuracy of greater than 14\%. If each particle type is functionalized with a different antibody, multiplex detection of two different analytes becomes feasible.}, language = {en} } @article{PourshahidiAchtsnichtOffenhaeusseretal.2022, author = {Pourshahidi, Ali Mohammad and Achtsnicht, Stefan and Offenh{\"a}usser, Andreas and Krause, Hans-Joachim}, title = {Frequency Mixing Magnetic Detection Setup Employing Permanent Ring Magnets as a Static Offset Field Source}, series = {Sensors}, volume = {22}, journal = {Sensors}, number = {22}, editor = {Offenh{\"a}usser, Andreas}, publisher = {MDPI}, address = {Basel}, issn = {1424-8220}, doi = {10.3390/s22228776}, pages = {12 Seiten}, year = {2022}, abstract = {Frequency mixing magnetic detection (FMMD) has been explored for its applications in fields of magnetic biosensing, multiplex detection of magnetic nanoparticles (MNP) and the determination of core size distribution of MNP samples. Such applications rely on the application of a static offset magnetic field, which is generated traditionally with an electromagnet. Such a setup requires a current source, as well as passive or active cooling strategies, which directly sets a limitation based on the portability aspect that is desired for point of care (POC) monitoring applications. In this work, a measurement head is introduced that involves the utilization of two ring-shaped permanent magnets to generate a static offset magnetic field. A steel cylinder in the ring bores homogenizes the field. By variation of the distance between the ring magnets and of the thickness of the steel cylinder, the magnitude of the magnetic field at the sample position can be adjusted. Furthermore, the measurement setup is compared to the electromagnet offset module based on measured signals and temperature behavior.}, language = {en} } @article{PourshahidiEngelmannOffenhaeusseretal.2022, author = {Pourshahidi, Ali Mohammad and Engelmann, Ulrich M. and Offenh{\"a}usser, Andreas and Krause, Hans-Joachim}, title = {Resolving ambiguities in core size determination of magnetic nanoparticles from magnetic frequency mixing data}, series = {Journal of Magnetism and Magnetic Materials}, volume = {563}, journal = {Journal of Magnetism and Magnetic Materials}, number = {In progress, Art. No. 169969}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0304-8853}, doi = {10.1016/j.jmmm.2022.169969}, year = {2022}, abstract = {Frequency mixing magnetic detection (FMMD) has been widely utilized as a measurement technique in magnetic immunoassays. It can also be used for the characterization and distinction (also known as "colourization") of different types of magnetic nanoparticles (MNPs) based on their core sizes. In a previous work, it was shown that the large particles contribute most of the FMMD signal. This leads to ambiguities in core size determination from fitting since the contribution of the small-sized particles is almost undetectable among the strong responses from the large ones. In this work, we report on how this ambiguity can be overcome by modelling the signal intensity using the Langevin model in thermodynamic equilibrium including a lognormal core size distribution fL(dc,d0,σ) fitted to experimentally measured FMMD data of immobilized MNPs. For each given median diameter d0, an ambiguous amount of best-fitting pairs of parameters distribution width σ and number of particles Np with R2 > 0.99 are extracted. By determining the samples' total iron mass, mFe, with inductively coupled plasma optical emission spectrometry (ICP-OES), we are then able to identify the one specific best-fitting pair (σ, Np) one uniquely. With this additional externally measured parameter, we resolved the ambiguity in core size distribution and determined the parameters (d0, σ, Np) directly from FMMD measurements, allowing precise MNPs sample characterization.}, language = {en} } @article{PredelGerdesGerling1979, author = {Predel, Bruno and Gerdes, F. and Gerling, Ulrich}, title = {Ber{\"u}cksichtigung der Assoziation in der Dampfphase bei Aktivit{\"a}tsbestimmungen und Revision der Aktivit{\"a}ten fl{\"u}ssiger Legierungen der Systeme Selen-Thallium, Selen-Wismut und Selen-Antimon}, series = {Zeitschrift f{\"u}r Metallkunde : international journal of materials research and advanced techniques. Bd. 70, H. 2}, journal = {Zeitschrift f{\"u}r Metallkunde : international journal of materials research and advanced techniques. Bd. 70, H. 2}, issn = {0044-3093 ; 0179-4841}, pages = {109 -- 112}, year = {1979}, language = {de} } @article{PresslerEsefeldScherretal.2010, author = {Pressler, Axel and Esefeld, Katrin and Scherr, Johannes and Ali, Mohammad and Hanssen, Henner and Kotliar, Konstantin and Lanzl, Ines and Halle, Martin and Kaemmerer, Harald and Schmidt-Trucks{\"a}ss, Arno and Hager, Alfred}, title = {Structural alterations of retinal arterioles in adults late after repair of aortic isthmic coarctation}, series = {The American Journal of Cardiology}, volume = {105}, journal = {The American Journal of Cardiology}, number = {5}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0002-9149}, doi = {10.1016/j.amjcard.2009.10.070}, pages = {740 -- 744}, year = {2010}, abstract = {Patients after coarctation repair still have an increased risk of cardiovascular or cerebrovascular events. This has been explained by the persisting hypertension and alterations in the peripheral vessels. However, involvement of the central vessels such as the retinal arteries is virtually unknown. A total of 34 patients after coarctation repair (22 men and 12 women; 23 to 58 years old, age range 0 to 32 years at surgical repair) and 34 nonhypertensive controls underwent structural and functional retinal vessel analysis. Using structural analysis, the vessel diameters were measured. Using functional analysis, the endothelium-dependent vessel dilation in response to flicker light stimulation was assessed. In the patients after coarctation repair, the retinal arteriolar diameter was significantly reduced compared to that of the controls (median 182 μm, first to third quartile 171 to 197; vs 197 μm, first to third quartile 193 to 206; p <0.001). These findings were independent of the peripheral blood pressure and age at intervention. No differences were found for venules. The functional analysis findings were not different between the patients and controls (maximum dilation 3.5\%, first to third quartile 2.1\% to 4.5\% vs 3.6\%, first to third quartile 2.2\% to 4.3\%; p = 0.81), indicating preserved autoregulative mechanisms. In conclusion, the retinal artery diameter is reduced in patients after coarctation repair, independent of their current blood pressure level and age at intervention. As a structural marker of chronic vessel damage associated with past, current, or future hypertension, retinal arteriolar narrowing has been linked to stroke incidence. These results indicate an involvement of cerebral microcirculation in aortic coarctation, despite timely repair, and might contribute to explain the increased rate of cerebrovascular events in such patients.}, language = {en} } @inproceedings{PrickingGebsFleischhakeretal.2015, author = {Pricking, Sebastian and Gebs, Raphael and Fleischhaker, Robert and Kleinbauer, Jochen and Budnicki, Aleksander and Sutter, Dirk and Killi, Alexander and Weiler, Sascha and Mielke, M. and Beaudou, B. and Debord, B. and Gerome, F. and Benabid, F.}, title = {Hollow core fiber delivery of sub-ps pulses from a TruMicro 5000 Femto edition thin disk amplifier}, series = {High-power laser materials processing: Lasers, beam delivery, diagnostics, and applications IV : 7 Februar 2015, San Francisco, USA. - (SPIE proceedings series ; 9356)}, booktitle = {High-power laser materials processing: Lasers, beam delivery, diagnostics, and applications IV : 7 Februar 2015, San Francisco, USA. - (SPIE proceedings series ; 9356)}, editor = {Dorsch, Friedhelm}, publisher = {SPIE, International Society for Optical Engineering}, organization = {The international society for optical engineering, SPIE <2, 2015, San Francisco, CA>}, isbn = {978-162841446-2}, issn = {0277-786X}, doi = {10.1117/12.2079289}, pages = {935602}, year = {2015}, language = {en} } @incollection{PriedeFerrein2013, author = {Priede, Gareth and Ferrein, Alexander}, title = {Towards passive walking for the fully-actuated biped robot Nao}, series = {Emerging trends in computing, informatics, systems sciences, and engineering. (Lecture notes in electrical engineering : vol. 151)}, booktitle = {Emerging trends in computing, informatics, systems sciences, and engineering. (Lecture notes in electrical engineering : vol. 151)}, publisher = {Springer}, address = {New York, NY}, isbn = {978-1-4614-3557-0 ; 978-1-4614-3558-7}, doi = {10.1007/978-1-4614-3558-7_18}, pages = {225 -- 236}, year = {2013}, abstract = {Many biped robots deploy a form of gait that follows the zero moment point (ZMP) approach, that is, the robot is in a stable position at any point in time. This requires the robot to be fully actuated. While very stable, the draw-backs of this approach are a fairly slow gait and high energy consumption. An alternative approach is the so-called passive-dynamic walking, where the gait makes use of the inertia and dynamic stability of the robot. In this paper we describe our ongoing work of combining the principles of passive-dynamic walking on the fully-actuated biped robot Nao, which is also deployed for robotic soccer applications. We present a simple controller that allows the robot to stably rock sidewards, showing a closed limit-cycle. We discuss first results of superimposing a forward motion on the sidewards motion. Based on this we expect to endow the Nao with a fast, robust, and stable passive-dynamic walk on the fully-actuated Nao in the future.}, language = {en} } @article{PrielmeierHoerstermannGyngelletal.1992, author = {Prielmeier, Franz and H{\"o}rstermann, D. and Gyngell, M. L. and Merboldt, K.-D.}, title = {Localized Proton MRS of Acute and Chronic Gyperglycemia in Rat Brain in vivo / D. H{\"o}rstermann, F. Prielmeier , M. L. Gyngell, K.-D. Merboldt, W. H{\"a}nicke, J. Frahm}, series = {Book of Abstracts, SMRM, 11th Annual Meeting Berlin}, journal = {Book of Abstracts, SMRM, 11th Annual Meeting Berlin}, pages = {2740}, year = {1992}, language = {en} } @article{PrielmeierLang1988, author = {Prielmeier, Franz and Lang, E. W.}, title = {Multinuclear Spin-Lattice Relaxation Time Studies of Supercooled Aqueous LiCl-Solutions / E .W. Lang, F. X. Prielmeier}, series = {Berichte der Bunsen-Gesellschaft f{\"u}r Physikalische Chemie. 92 (1988)}, journal = {Berichte der Bunsen-Gesellschaft f{\"u}r Physikalische Chemie. 92 (1988)}, isbn = {0005-9021}, pages = {717}, year = {1988}, language = {en} } @article{PrielmeierLangLuedemann1984, author = {Prielmeier, Franz and Lang, E. W. and L{\"u}demann, H.-D.}, title = {Pressure dependence of the self-diffusion in liquid trifluoromethane / F. X. Prielmeier; E. W. Lang; H.-D. L{\"u}demann}, series = {Molecular Physics. 52 (1984), H. 5}, journal = {Molecular Physics. 52 (1984), H. 5}, isbn = {0026-8976}, pages = {1105 -- 1113}, year = {1984}, language = {en} } @article{PrielmeierLangRadkowitschetal.1987, author = {Prielmeier, Franz and Lang, E. W. and Radkowitsch, H. and L{\"u}demann, H. D.}, title = {High Pressure NMR Study of the Molecular Dynamics of Liquid fluoroform and deutero-fluoroform / Lang, E. W. ; Prielmeier, F. X. ; Radkowitsch, H. ; L{\"u}demann, H. D.}, series = {Berichte der Bunsen-Gesellschaft f{\"u}r Physikalische Chemie. 91 (1987), H. 10}, journal = {Berichte der Bunsen-Gesellschaft f{\"u}r Physikalische Chemie. 91 (1987), H. 10}, isbn = {0005-9021}, pages = {1025 -- 1033}, year = {1987}, language = {en} } @article{PrielmeierLangRadkowitschetal.1987, author = {Prielmeier, Franz and Lang, E. W. and Radkowitsch, H. and L{\"u}demann, H.-D.}, title = {High Pressure NMR Study of the Molecular Dynamics of Liquid methyl fluoride and deutero-methyl fluoride / Lang, E. W. ; Prielmeier, F. X. ; Radkowitsch, H. ; L{\"u}demann, H. D.}, series = {Berichte der Bunsen-Gesellschaft f{\"u}r Physikalische Chemie. 91 (1987), H. 10}, journal = {Berichte der Bunsen-Gesellschaft f{\"u}r Physikalische Chemie. 91 (1987), H. 10}, isbn = {0005-9021}, pages = {1017 -- 1025}, year = {1987}, language = {en} }