@article{ScheerKapelyukhRodeetal.2012, author = {Scheer, Nico and Kapelyukh, Yury and Rode, Anja and Buechel, Sandra and Wolf, C. Roland}, title = {Generation and characterization of novel cytochrome P450 Cyp2c gene cluster knockout and CYP2C9 humanized mouse lines}, series = {Molecular Pharmacology}, volume = {82}, journal = {Molecular Pharmacology}, number = {6}, publisher = {ASPET}, address = {Bethesda, Md.}, issn = {1521-0111}, doi = {10.1124/mol.112.080036}, pages = {1022 -- 1029}, year = {2012}, abstract = {Compared with rodents and many other animal species, the human cytochrome P450 (P450) Cyp2c gene cluster varies significantly in the multiplicity of functional genes and in the substrate specificity of its enzymes. As a consequence, the use of wild-type animal models to predict the role of human CYP2C enzymes in drug metabolism and drug-drug interactions is limited. Within the human CYP2C cluster CYP2C9 is of particular importance, because it is one of the most abundant P450 enzymes in human liver, and it is involved in the metabolism of a wide variety of important drugs and environmental chemicals. To investigate the in vivo functions of cytochrome P450 Cyp2c genes and to establish a model for studying the functions of CYP2C9 in vivo, we have generated a mouse model with a deletion of the murine Cyp2c gene cluster and a corresponding humanized model expressing CYP2C9 specifically in the liver. Despite the high number of functional genes in the mouse Cyp2c cluster and the reported roles of some of these proteins in different biological processes, mice deleted for Cyp2c genes were viable and fertile but showed certain phenotypic alterations in the liver. The expression of CYP2C9 in the liver also resulted in viable animals active in the metabolism and disposition of a number of CYP2C9 substrates. These mouse lines provide a powerful tool for studying the role of Cyp2c genes and of CYP2C9 in particular in drug disposition and as a factor in drug-drug interaction.}, language = {en} } @article{ScheerKapelyukhRodeetal.2015, author = {Scheer, Nico and Kapelyukh, Yury and Rode, Anja and Oswald, Stefan and Busch, Diana and Mclaughlin, Lesley A. and Lin, De and Henderson, Colin J. and Wolf, C. Roland}, title = {Defining Human Pathways of Drug Metabolism In Vivo through the Development of a Multiple Humanized Mouse Model}, series = {Drug Metabolism and Disposition}, volume = {43}, journal = {Drug Metabolism and Disposition}, number = {11}, publisher = {ASPET}, address = {Bethesda}, issn = {1521-009x}, doi = {10.1124/dmd.115.065656}, pages = {1679 -- 1690}, year = {2015}, language = {en} } @article{ScheerMclaughlinRodeetal.2014, author = {Scheer, Nico and Mclaughlin, Lesley A. and Rode, Anja and MacLeod, Alastair Kenneth and Henderson, Colin J. and Wolf, Roland C.}, title = {Deletion of thirty murine cytochrome P450 genes results in viable mice with compromised drug metabolism}, series = {Drug Metabolism and Disposition}, volume = {42}, journal = {Drug Metabolism and Disposition}, number = {6}, publisher = {ASPET}, address = {Bethesda, Md.}, issn = {1521-009X}, doi = {10.1124/dmd.114.057885}, pages = {1022 -- 1030}, year = {2014}, abstract = {In humans, 75\% of all drugs are metabolized by the cytochrome P450-dependent monooxygenase system. Enzymes encoded by the CYP2C, CYP2D, and CYP3A gene clusters account for ∼80\% of this activity. There are profound species differences in the multiplicity of cytochrome P450 enzymes, and the use of mouse models to predict pathways of drug metabolism is further complicated by overlapping substrate specificity between enzymes from different gene families. To establish the role of the hepatic and extrahepatic P450 system in drug and foreign chemical disposition, drug efficacy, and toxicity, we created a unique mouse model in which 30 cytochrome P450 genes from the Cyp2c, Cyp2d, and Cyp3a gene clusters have been deleted. Remarkably, despite a wide range of putative important endogenous functions, Cyp2c/2d/3a KO mice were viable and fertile, demonstrating that these genes have evolved primarily as detoxification enzymes. Although there was no overt phenotype, detailed examination showed Cyp2c/2d/3a KO mice had a smaller body size (15\%) and larger livers (20\%). Changes in hepatic morphology and a decreased blood glucose (30\%) were also noted. A five-drug cocktail of cytochrome P450 isozyme probe substrates were used to evaluate changes in drug pharmacokinetics; marked changes were observed in either the pharmacokinetics or metabolites formed from Cyp2c, Cyp2d, and Cyp3a substrates, whereas the metabolism of the Cyp1a substrate caffeine was unchanged. Thus, Cyp2c/2d/3a KO mice provide a powerful model to study the in vivo role of the P450 system in drug metabolism and efficacy, as well as in chemical toxicity.}, language = {en} } @article{ScheerRiedlWarrenetal.2002, author = {Scheer, Nico and Riedl, Iris and Warren, J.T. and Kuwada, John Y. and Campos-Ortega, Jos{\´e} A.}, title = {A quantitative analysis of the kinetics of Gal4 activator and effector gene expression in the zebrafish}, series = {Mechanism of Development}, volume = {112}, journal = {Mechanism of Development}, number = {1-2}, issn = {0925-4773}, doi = {10.1016/S0925-4773(01)00621-9}, pages = {9 -- 14}, year = {2002}, language = {en} } @article{ScheerRossKapelyukhetal.2010, author = {Scheer, Nico and Ross, Jillian and Kapelyukh, Yury and Rode, Anja and Wolf, C. Roland}, title = {In vivo responses of the human and murine pregnane X receptor to dexamethasone in mice}, series = {Drug Metabolism and Disposition}, volume = {38}, journal = {Drug Metabolism and Disposition}, number = {7}, publisher = {ASPET}, address = {Bethesda}, issn = {1521-009X}, doi = {10.1124/dmd.109.031872}, pages = {1046 -- 1053}, year = {2010}, abstract = {Dexamethasone (DEX) is a potent and widely used anti-inflammatory and immunosuppressant glucocorticoid. It can bind and activate the pregnane X receptor (PXR), which plays a critical role as xenobiotic sensor in mammals to induce the expression of many enzymes, including cytochromes P450 in the CYP3A family. This induction results in its own metabolism. We have used a series of transgenic mouse lines, including a novel, improved humanized PXR line, to compare the induction profile of PXR-regulated drug-metabolizing enzymes after DEX administration, as well as looking at hepatic responses to rifampicin (RIF). The new humanized PXR model has uncovered further intriguing differences between the human and mouse receptors in that RIF only induced Cyp2b10 in the new humanized model. DEX was found to be a much more potent inducer of Cyp3a proteins in wild-type mice than in mice humanized for PXR. To assess whether PXR is involved in the detoxification of DEX in the liver, we analyzed the consequences of high doses of the glucocorticoid on hepatotoxicity on different PXR genetic backgrounds. We also studied these effects in an additional mouse model in which functional mouse Cyp3a genes have been deleted. These strains exhibited different sensitivities to DEX, indicating a protective role of the PXR and CYP3A proteins against the hepatotoxicity of this compound.}, language = {en} } @article{ScheerRossRodeetal.2008, author = {Scheer, Nico and Ross, Jillian and Rode, Anja and Zevnik, Branko and Niehaves, Sandra and Faust, Nicole and Wolf, C. Roland}, title = {A novel panel of mouse models to evaluate the role of human pregnane X receptor and constitutive androstane receptor in drug response}, series = {Journal of Clinical Investigation}, volume = {118}, journal = {Journal of Clinical Investigation}, number = {9}, issn = {1558-8238}, doi = {https://doi.org/10.1172/JCI35483}, pages = {3228 -- 3239}, year = {2008}, language = {en} } @article{ScheerSnaithWolfetal.2013, author = {Scheer, Nico and Snaith, Mike and Wolf, C. Roland and Seibler, Jost}, title = {Generation and utility of genetically humanized mouse models}, series = {Drug Discovery Today}, volume = {Vol 18}, journal = {Drug Discovery Today}, number = {23-24}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1359-6446}, doi = {10.1016/j.drudis.2013.07.007}, pages = {1200 -- 1211}, year = {2013}, language = {en} } @article{ScheerWilson2016, author = {Scheer, Nico and Wilson, Ian D.}, title = {A comparison between genetically humanized and chimeric liver humanized mouse models for studies in drug metabolism and toxicity}, series = {Drug Discovery Today}, volume = {21}, journal = {Drug Discovery Today}, number = {2}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1359-6446}, doi = {10.1016/j.drudis.2015.09.002}, pages = {250 -- 263}, year = {2016}, abstract = {Mice that have been genetically humanized for proteins involved in drug metabolism and toxicity and mice engrafted with human hepatocytes are emerging and promising in vivo models for an improved prediction of the pharmacokinetic, drug-drug interaction and safety characteristics of compounds in humans. The specific advantages and disadvantages of these models should be carefully considered when using them for studies in drug discovery and development. Here, an overview on the corresponding genetically humanized and chimeric liver humanized mouse models described to date is provided and illustrated with examples of their utility in drug metabolism and toxicity studies. We compare the strength and weaknesses of the two different approaches, give guidance for the selection of the appropriate model for various applications and discuss future trends and perspectives.}, language = {en} } @article{ScheerWolf2014, author = {Scheer, Nico and Wolf, C. Roland}, title = {Genetically humanized mouse models of drug metabolizing enzymes and transporters and their applications}, series = {Xenobiotica}, volume = {44}, journal = {Xenobiotica}, number = {2}, publisher = {Taylor \& Francis}, address = {Abingdon}, issn = {1366-5928}, doi = {10.3109/00498254.2013.815831}, pages = {96 -- 108}, year = {2014}, abstract = {1. Drug metabolizing enzymes and transporters play important roles in the absorption, metabolism, tissue distribution and excretion of various compounds and their metabolites and thus can significantly affect their efficacy and safety. Furthermore, they can be involved in drug-drug interactions which can result in adverse responses, life-threatening toxicity or impaired efficacy. Significant species differences in the interaction of compounds with drug metabolizing enzymes and transporters have been described. 2. In order to overcome the limitation of animal models in accurately predicting human responses, a large variety of mouse models humanized for drug metabolizing enzymes and to a lesser extent drug transporters have been created. 3. This review summarizes the literature describing these mouse models and their key applications in studying the role of drug metabolizing enzymes and transporters in drug bioavailability, tissue distribution, clearance and drug-drug interactions as well as in human metabolite testing and risk assessment. 4. Though such humanized mouse models have certain limitations, there is great potential for their use in basic research and for testing and development of new medicines. These limitations and future potentials will be discussed.}, language = {en} } @article{ScheerWolf2013, author = {Scheer, Nico and Wolf, C. Roland}, title = {Xenobiotic receptor humanized mice and their utility}, series = {Drug Metabolism Reviews}, journal = {Drug Metabolism Reviews}, number = {1}, publisher = {Taylor \& Francis}, address = {London}, issn = {1097-9883}, doi = {10.3109/03602532.2012.738687}, pages = {110 -- 121}, year = {2013}, language = {en} } @masterthesis{Scheffel2023, type = {Bachelor Thesis}, author = {Scheffel, Zeno Samuel}, title = {Identit{\"a}t, Zusammenhalt, Zugeh{\"o}rigkeit : Die Exploration der Gestaltung von Fußballtrikots}, publisher = {FH Aachen}, address = {Aachen}, pages = {95 Seiten}, year = {2023}, abstract = {Das Fußballtrikot - Arbeitsbekleidung, Identifikationsmerkmal, Distinktionsmerkmal? Was ist das Fußballtrikot, was sind seine identit{\"a}tsstiftenden Merkmale und welche Gestaltungsparameter pr{\"a}gen sein heutiges Aussehen? In dieser Publikation wird die Geschichte des Trikots ebenso wie die {\"a}ußeren Einfl{\"u}sse auf sein heutiges Erscheinungsbild dokumentiert und analysiert. Die Publikation definiert die verschiedenen Gestaltungsparameter, erl{\"a}utert diese und ordnet sie ein. Ebenso wird ein Einblick in den kreativen Gestaltungsprozess von Fußballtrikots gew{\"a}hrt. Das Ziel dieser Publikation besteht darin, das Erscheinungsbild von Trikots zu verstehen und eine kritische Reflexion dar{\"u}ber zu erm{\"o}glichen, wie das Fußballtrikot individuell definiert wird.}, language = {de} } @inproceedings{ScheibeKern2013, author = {Scheibe, K. and Kern, Alexander}, title = {Stand der Normung f{\"u}r {\"U}berspannungsschutzger{\"a}te}, series = {10. VDE, VBB-Blitzschutztagung : Vortr{\"a}ge der 10. VDE, ABB-Fachtagung vom 24. bis 25. Oktober 2013 in Neu-Ulm. (VDE-Fachbericht ; 70)}, booktitle = {10. VDE, VBB-Blitzschutztagung : Vortr{\"a}ge der 10. VDE, ABB-Fachtagung vom 24. bis 25. Oktober 2013 in Neu-Ulm. (VDE-Fachbericht ; 70)}, publisher = {VDE-Verl.}, address = {Berlin}, organization = {Blitzschutztagung <10, 2013, Neu-Ulm>}, isbn = {978-3-8007-3540-2}, pages = {23 -- 27}, year = {2013}, language = {de} } @article{ScheibeKern2011, author = {Scheibe, Klaus and Kern, Alexander}, title = {Aktueller Stand der Normung zum {\"U}berspannungschutz}, series = {9. VDE/ABB-Blitzschutztagung : Vortr{\"a}ge der 9. VDE/ABB-Fachtagung vom 27. bis 28. Oktober 2011 in Neu-Ulm / Veranst.: Ausschuss f{\"u}r Blitzschutz und Blitzforschung (ABB) im VDE Verband der Elektrotechnik Elektronik Informationstechnik e.V. Wiss. Tagungsleitung: K. Stimper}, journal = {9. VDE/ABB-Blitzschutztagung : Vortr{\"a}ge der 9. VDE/ABB-Fachtagung vom 27. bis 28. Oktober 2011 in Neu-Ulm / Veranst.: Ausschuss f{\"u}r Blitzschutz und Blitzforschung (ABB) im VDE Verband der Elektrotechnik Elektronik Informationstechnik e.V. Wiss. Tagungsleitung: K. Stimper}, publisher = {VDE-Verl.}, address = {Berlin}, isbn = {978-3-8007-3380-4}, pages = {13 -- 17}, year = {2011}, language = {de} } @article{ScheidweilerTriesch2016, author = {Scheidweiler, Robert and Triesch, Eberhard}, title = {A note on the duality between matchings and vertex covers in balanced hypergraphs}, series = {Journal of Combinatorial Optimization}, volume = {32}, journal = {Journal of Combinatorial Optimization}, number = {2}, publisher = {Springer}, address = {Berlin}, issn = {1573-2886}, doi = {10.1007/s10878-015-9887-5}, pages = {639 -- 644}, year = {2016}, abstract = {We present a new Min-Max theorem for an optimization problem closely connected to matchings and vertex covers in balanced hypergraphs. The result generalizes Kőnig's Theorem (Berge and Las Vergnas in Ann N Y Acad Sci 175:32-40, 1970; Fulkerson et al. in Math Progr Study 1:120-132, 1974) and Hall's Theorem (Conforti et al. in Combinatorica 16:325-329, 1996) for balanced hypergraphs.}, language = {en} } @inproceedings{ScheikReisgenSchleseretal.2012, author = {Scheik, Sven and Reisgen, Uwe and Schleser, Markus and Huber, Frederic}, title = {Untersuchungen zum dehnungsbasierten Versagen von geklebten, oberfl{\"a}chenveredelten Blechen im Zugscherversuch}, series = {2. Doktorandenseminar Klebtechnik : Vortr{\"a}ge der gleichnamigen Veranstaltung in Dresden am 5. und 6. September 2011}, booktitle = {2. Doktorandenseminar Klebtechnik : Vortr{\"a}ge der gleichnamigen Veranstaltung in Dresden am 5. und 6. September 2011}, publisher = {DVS-Media}, address = {D{\"u}sseldorf}, organization = {Institut f{\"u}r Schweißtechnik und F{\"u}getechnik Aachen> ; Doktorandenseminar Klebtechnik <2, 2011, Dresden>}, isbn = {978-3-87155-599-2}, pages = {73 -- 78}, year = {2012}, language = {de} } @inproceedings{ScheikReisgenSchleseretal.2012, author = {Scheik, Sven and Reisgen, Uwe and Schleser, Markus and Huber, Frederic}, title = {Untersuchungen zum dehnungsbasierten Versagen von geklebten, oberfl{\"a}chenveredelten Blechen im Zugscherversuch}, series = {2. Doktorandenseminar Klebtechnik : Vortr{\"a}ge der gleichnamigen Veranstaltung in Dresden am 5. und 6. September 2011. (DVS-Berichte ; 292)}, booktitle = {2. Doktorandenseminar Klebtechnik : Vortr{\"a}ge der gleichnamigen Veranstaltung in Dresden am 5. und 6. September 2011. (DVS-Berichte ; 292)}, publisher = {DVS Media}, address = {D{\"u}sseldorf}, organization = {Doktorandenseminar Klebtechnik <2, 2011, Dresden> ; Institut f{\"u}r Schweißtechnik und F{\"u}getechnik }, isbn = {978-3-87155-599-2}, pages = {73 -- 78}, year = {2012}, language = {de} } @article{ScheikSchleserReisgen2012, author = {Scheik, Sven and Schleser, Markus and Reisgen, Uwe}, title = {Thermisches Direktf{\"u}gen von Metall und Kusntstoff: eine Alternative zur Klebtechnik}, series = {Adh{\"a}sion : Kleben \& Dichten}, volume = {56}, journal = {Adh{\"a}sion : Kleben \& Dichten}, number = {11}, publisher = {Springer Vieweg}, address = {Wiesbaden}, issn = {0001-8198 (E-Journal); 0001-8198 (Print)}, doi = {10.1007/s35145-012-0005-x}, pages = {36 -- 40}, year = {2012}, abstract = {Im Rahmen des Exzellenzclusters „Integrative Produktionstechnik f{\"u}r Hochlohnl{\"a}nder" der RWTHAachen University werden derzeit alternative Verfahren zur Herstellung von Metall/Kunststoff- Verbindungen untersucht. Eines davon ist das thermische Direktf{\"u}gen, das eine stoffschl{\"u}ssige Verbindung zwischen Kunststoff und Metall erm{\"o}glicht und ohne die Verwendung von Klebstoffen, Haftvermittlern oder mechanischen Verbindungshilfen auskommt.}, language = {de} } @book{Schelthoff2006, author = {Schelthoff, Christof}, title = {Mathematik im Bachelor- und Diplomstudium f{\"u}r Bio- und Chemieingenieure}, publisher = {Shaker}, address = {Aachen}, isbn = {978-3-8322-5309-7}, pages = {458 S. : Ill., graph. Darst.}, year = {2006}, language = {de} } @book{Schelthoff2007, author = {Schelthoff, Christof}, title = {Mathematik im Bachelorstudium f{\"u}r Studierende der Biotechnologie, der Prozesstechnik und der angewandten Chemie. 2. {\"u}berarb. Aufl.}, publisher = {Shaker}, address = {Aachen}, isbn = {978-3-8322-6507-6}, pages = {478 S.}, year = {2007}, language = {de} } @book{Schelthoff1997, author = {Schelthoff, Christof}, title = {Modellierung der SOFC-Brennstoffzelle und die numerische L{\"o}sung mit einem adaptiven Full-Multigrid-Verfahren}, publisher = {Forschungszentrum J{\"u}lich, Zentralbibliothek}, address = {J{\"u}lich}, pages = {VI, 100 S. : graph. Darst.}, year = {1997}, language = {de} } @book{Schelthoff1994, author = {Schelthoff, Christof}, title = {Vergleich von parallelen Verfahren zur Vorkonditionierung f{\"u}r die Methode der konjugierten Gradienten}, publisher = {Forschungszentrum J{\"u}lich}, address = {J{\"u}lich}, pages = {VI, 87 S.}, year = {1994}, language = {de} } @book{Schelthoff2010, author = {Schelthoff, Christof}, title = {Mathematik im ingenieurwissenschaftlichen Bachelorstudium / 4., {\"u}berarb. Aufl.}, publisher = {Shaker}, address = {Aachen}, isbn = {978-3-8322-9288-1}, pages = {542 S. : graph. Darst.}, year = {2010}, language = {de} } @book{Schelthoff2010, author = {Schelthoff, Christof}, title = {Mathematik im ingenieurwissenschaftlichen Bachelorstudium : L{\"o}sung der {\"U}bungs- und Klausuraufgaben}, publisher = {Shaker}, address = {Aachen}, isbn = {978-3-8322-9502-8}, pages = {171 S. : Ill., graph. Darst.}, year = {2010}, language = {de} } @article{SchelthoffBasermann1995, author = {Schelthoff, Christof and Basermann, Achim}, title = {Polynomial Preconditioning for the Conjugate Gradient Method on Massively Parallel Systems}, series = {Workshop {\"u}ber Parallelverarbeitung : Lessach ({\"O}sterreich), 26.9.-30.9.1994 / Institut f{\"u}r Informatik, Clausthal-Zellerfeld. Klaus Ecker; J{\"o}rg Apsel}, journal = {Workshop {\"u}ber Parallelverarbeitung : Lessach ({\"O}sterreich), 26.9.-30.9.1994 / Institut f{\"u}r Informatik, Clausthal-Zellerfeld. Klaus Ecker; J{\"o}rg Apsel}, publisher = {Inst. f{\"u}r Informatik}, address = {Clausthal-Zellerfeld}, pages = {150 -- 167}, year = {1995}, language = {de} } @article{SchelthoffBasermannReichel1997, author = {Schelthoff, Christof and Basermann, Achim and Reichel, Bj{\"o}rn}, title = {Preconditioned CG methods for sparse matrices on massively parallel machines / Basermann, A. ; Reichel, B. ; Schelthoff, C.}, series = {Parallel Computing. 23 (1997), H. 3}, journal = {Parallel Computing. 23 (1997), H. 3}, isbn = {0167-8191}, pages = {381 -- 398}, year = {1997}, language = {en} } @article{SchelthoffSteffen1996, author = {Schelthoff, Christof and Steffen, Bernhard}, title = {Modellierung und Simulation am Beispiel von Hochtemperatur-Brennstoffzellen}, series = {Praxis der Informationsverarbeitung und Kommunikation : PIK. 19 (1996), H. 3}, journal = {Praxis der Informationsverarbeitung und Kommunikation : PIK. 19 (1996), H. 3}, isbn = {0930-5157}, pages = {138 -- 141}, year = {1996}, language = {de} } @article{SchelthoffSteffenWeidneretal.1997, author = {Schelthoff, Christof and Steffen, Bernhard and Weidner, Peter and Hoßfeld, Friedel}, title = {Hochaufl{\"o}sende Modellierung von SOFC-Brennstoffzellen / Schelthoff, Christof ; Steffen, Bernhard ; Weidner, Peter ; Hoßfeld, Friedel ; Divisek, J. ; Jung, Rita}, series = {Mathematik : Schl{\"u}sseltechnologie f{\"u}r die Zukunft ; Verbundprojekte zwischen Universit{\"a}t und Industrie ; mit 33 Tabellen / Karl-Heinz Hoffmann ... (Hrsg.)}, journal = {Mathematik : Schl{\"u}sseltechnologie f{\"u}r die Zukunft ; Verbundprojekte zwischen Universit{\"a}t und Industrie ; mit 33 Tabellen / Karl-Heinz Hoffmann ... (Hrsg.)}, publisher = {Springer}, address = {Berlin}, isbn = {3-540-61677-2}, pages = {105 -- 115}, year = {1997}, language = {de} } @incollection{SchemmLintzelBorchert2005, author = {Schemm, R. and Lintzel, P. and Borchert, J{\"o}rg}, title = {Typische Elemente des Handelsmarktes}, series = {Energiehandel in Europa}, booktitle = {Energiehandel in Europa}, editor = {Zenke, Ines}, publisher = {Beck}, address = {M{\"u}nchen}, isbn = {3-406-52443-5}, pages = {195 -- 216}, year = {2005}, language = {de} } @masterthesis{Scherer2022, type = {Bachelor Thesis}, author = {Scherer, Maike}, title = {Social Integrity for distributed Workforces : ein Design System f{\"u}r soziale Interaktion eines Unternehmens}, publisher = {FH Aachen}, address = {Aachen}, pages = {125 Seiten}, year = {2022}, abstract = {Eine Applikation f{\"u}r die soziale Interaktion zwischen Teams und Arbeitnehmern eines Unternehmens, welche Remote und/oder Hybrid arbeiten. Wissen teilen, Weiterbilden, Wohlf{\"u}hlen In den letzten zwei Jahren kam es auf Grund der Corona-Pandemie, trotz der vielen Kommunikationsm{\"o}glichkeiten, im Privat-, sowie Arbeitsleben zu erheblichen sozialen Einschr{\"a}nkungen. Genau hier setzt die Applikation „Companion" an, um dem Arbeitnehmer das In-Office-Gef{\"u}hl auch Remote {\"u}bersetzen zu k{\"o}nnen. Der Arbeitnehmer kann mit seinen Kollegen sozialisieren, diese besser kennenlernen und wird zus{\"a}tzlich durch Events und Workshops professionell weitergebildet.}, language = {de} } @article{Scherer1997, author = {Scherer, Ulrich W.}, title = {Zur Radiopharmazie kardialer und kardiovaskul{\"a}rer Radiopharmazeutika}, series = {Kardiologische Nuklearmedizin / G. H{\"o}r [Hrsg.]}, journal = {Kardiologische Nuklearmedizin / G. H{\"o}r [Hrsg.]}, publisher = {ecomed}, address = {Landsberg}, isbn = {3-609-62970-3}, pages = {27 -- 42}, year = {1997}, language = {de} } @article{Scherer2006, author = {Scherer, Ulrich W.}, title = {Controlled ion track etching / J. George; M. Irkens ; S. Neumann ; U. W. Scherer ; A. Srivastava ; D. Sinha ; D. Fink}, series = {Radiation Effects and Defects in Solids. 161 (2006), H. 3}, journal = {Radiation Effects and Defects in Solids. 161 (2006), H. 3}, pages = {161 -- 175}, year = {2006}, language = {en} } @book{Scherer1989, author = {Scherer, Ulrich W.}, title = {Untersuchungen zur Synthese und chemischen Charakterisierung sehr schwerer Elemente / Ulrich W. Scherer}, publisher = {Gesellschaft f{\"u}r Schwerionenforschung mbH}, address = {Darmstadt}, pages = {123 S.}, year = {1989}, language = {de} } @book{Scherer2001, author = {Scherer, Ulrich W.}, title = {Ultraschnelle Analytik radioaktiver Wirkstoffe : Abschlußbericht zu Nr. 3.2 und Anlage 2 BNBest-BMBF 98 ; Laufzeit des Vorhabens: 1.9.1999 -28.2.2001 / Zuwendungsempf{\"a}nger: Ulrich W. Scherer}, publisher = {Universit{\"a}tsbibliothek u. Technische Informationsbibliothek}, address = {Hannover}, pages = {Elektronische Ressource}, year = {2001}, language = {de} } @article{SchererBaltenspergerAmmannetal.1993, author = {Scherer, Ulrich W. and Baltensperger, Urs and Ammann, Markus and Bochert, Ulrich K.}, title = {Use of 13N for Studies of the Selective Reduction of NO by NH3 over Vanadia/Titania Catalyst at Very Low Reactant Concentrations / Urs Baltensperger, Markus Ammann, Ulrich K. Bochert, Bernd Eichler, Heinz W. G{\"a}ggeler, Dieter T. Jost, Joseph A. Kovacs, An}, series = {Journal of Physical Chemistry. 97 (1993)}, journal = {Journal of Physical Chemistry. 97 (1993)}, isbn = {0022-3654}, pages = {12325 -- 12330}, year = {1993}, language = {en} } @article{SchererBruechleBrueggeretal.1990, author = {Scherer, Ulrich W. and Br{\"u}chle, W. and Br{\"u}gger, M. and Frink, C.}, title = {Reactions of 40Ar with 233U,,235U, and 238U at the Barrier / U.W. Scherer, W. Br{\"u}chle, M. Br{\"u}gger, C. Frink, H. G{\"a}ggeler, G. Herrmann, J.V. Kratz, K.J. Moody, M. Sch{\"a}del, K. S{\"u}mmerer, N. Trautmann, G. Wirth}, series = {Zeitschrift f{\"u}r Physik A Hadrons and Nuclei. 335 (1990), H. 4}, journal = {Zeitschrift f{\"u}r Physik A Hadrons and Nuclei. 335 (1990), H. 4}, isbn = {0939-7922}, pages = {421 -- 430}, year = {1990}, language = {en} } @article{SchererBruechleSchaedeletal.1988, author = {Scherer, Ulrich W. and Br{\"u}chle, W. and Sch{\"a}del, M. and Kratz, J. V.}, title = {The Hydration Enthalpies of Md3+ and Lr3+ / W. Br{\"u}chle, M. Sch{\"a}del, U.W. Scherer, J.V. Kratz, K.E. Gregorich, D. Lee, M. Nurmia, R.M. Chasteler, H.L. Hall, R.A. Henderson, D.C. Hoffman}, series = {Inorganica Chimica Acta. 146 (1988), H. 2}, journal = {Inorganica Chimica Acta. 146 (1988), H. 2}, isbn = {0020-1693}, pages = {267 -- 276}, year = {1988}, language = {en} } @article{SchererGoberKratzetal.1992, author = {Scherer, Ulrich W. and Gober, M. K. and Kratz, J. V. and Zimmermann, H. P.}, title = {Chemical Properties of Element 105 in Aqueous Solution: Extractions into Diisobutylcarbinol / M.K. Gober, J.V. Kratz, H.P. Zimmermann, M. Sch{\"a}del, W. Br{\"u}chle, E. Schimpf, K.E. Gregorich, A. T{\"u}rler, N.J. Hannink, K.R. Czerwinski, B. Kadkhodayan, D.M. Lee,}, series = {Radiochimica Acta. 57 (1992)}, journal = {Radiochimica Acta. 57 (1992)}, isbn = {0033-8230}, pages = {77 -- 84}, year = {1992}, language = {en} } @article{SchererGaeggelerJostetal.1992, author = {Scherer, Ulrich W. and G{\"a}ggeler, H. W. and Jost, D. T. and Kovacs, J.}, title = {Gas Phase Chromatography Experiments with Bromides of Tantalum and Element 105 / H.W. G{\"a}ggeler, D.T. Jost, J. Kovacs, U.W. Scherer, A. Weber, D. Vermeulen, A. T{\"u}rler, K.E. Gregorich, R.A. Henderson, K.R. Czerwinski, B. Kadkhodayan, D.M. Lee, M. Nurmia, D.}, series = {Radiochimica Acta. 57 (1992)}, journal = {Radiochimica Acta. 57 (1992)}, isbn = {0033-8230}, pages = {93 -- 100}, year = {1992}, language = {en} } @article{SchererGaeggelerJostetal.1989, author = {Scherer, Ulrich W. and G{\"a}ggeler, H. W. and Jost, D. T. and T{\"u}rler, A.}, title = {Cold Fusion Reactions with 48Ca / H.W. G{\"a}ggeler, D.T. Jost, A. T{\"u}rler, P. Armbruster, W. Br{\"u}chle, H. Folger, F.P. Heßberger, S. Hofmann, G. M{\"u}nzenberg, V. Ninov, W. Reisdorf, M. Sch{\"a}del, K. S{\"u}mmerer, J.V. Kratz, U. Scherer, M.E. Leino}, series = {Nuclear Physics A . 502 (1989), H. 1}, journal = {Nuclear Physics A . 502 (1989), H. 1}, isbn = {0375-9474}, pages = {561 -- 570}, year = {1989}, language = {en} } @article{SchererHessbergerGaeggeleretal.1989, author = {Scherer, Ulrich W. and Heßberger, F. P. and G{\"a}ggeler, H. W. and Armbruster, P.}, title = {The New Nuclide 225U / F.P. Heßberger, H. G{\"a}ggeler, P. Armbruster, W. Br{\"u}chle, H. Folger, S. Hofmann, D. Jost, J.V. Kratz, M.E. Leino, G. M{\"u}nzenberg, V. Ninov, M. Sch{\"a}del, U.W. Scherer, K. S{\"u}mmerer, A. T{\"u}rler, D. Ackerman}, series = {Zeitschrift f{\"u}r Physik A Hadrons and Nuclei. 333 (1989), H. 1}, journal = {Zeitschrift f{\"u}r Physik A Hadrons and Nuclei. 333 (1989), H. 1}, isbn = {0939-7922}, pages = {111 -- 112}, year = {1989}, language = {en} } @article{SchererHoer1997, author = {Scherer, Ulrich W. and H{\"o}r, G.}, title = {Kompartimentmodelle zur Quantifizierung des myokardialen Stoffwechsels mit PET / U. W. Scherer, G. H{\"o}r}, series = {Kardiologische Nuklearmedizin / G. H{\"o}r [Hrsg.]}, journal = {Kardiologische Nuklearmedizin / G. H{\"o}r [Hrsg.]}, publisher = {ecomed}, address = {Landsberg}, isbn = {3-609-62970-3}, pages = {179 -- 189}, year = {1997}, language = {de} } @article{SchererHoer1997, author = {Scherer, Ulrich W. and H{\"o}r, G.}, title = {Artifacts and Pitfalls in FDG-PET Whole-Body Scans / U.W. Scherer, G. H{\"o}r}, series = {Radionuclides for Mammary Gland - Current Status and Future Aspects / G. S. Limouris [Hrsg.]}, journal = {Radionuclides for Mammary Gland - Current Status and Future Aspects / G. S. Limouris [Hrsg.]}, publisher = {Mediterra Publishers}, address = {Athen}, isbn = {960-85227-6-5}, pages = {37 -- 42}, year = {1997}, language = {en} } @article{SchererHoerHertel1998, author = {Scherer, Ulrich W. and H{\"o}r, G. and Hertel, A.}, title = {Positronen-Emissions-Tomographie des Herzens / G. H{\"o}r, A. Hertel, U. W. Scherer}, series = {Herzerkrankungen und Interventionsm{\"o}glichkeiten / F. Unger [Hrsg.]}, journal = {Herzerkrankungen und Interventionsm{\"o}glichkeiten / F. Unger [Hrsg.]}, publisher = {Springer}, address = {Berlin}, isbn = {3-540-62916-5}, pages = {236 -- 263}, year = {1998}, language = {de} } @article{SchererHoerKranertetal.1998, author = {Scherer, Ulrich W. and H{\"o}r, G. and Kranert, W. T. and Maul, F. D.}, title = {Gated Metabolic Positron Emission Tomography (GAPET) of Myocardium: 18F-FDG/PET to optimize Recognition of Myocardial Hibernation / G. H{\"o}r, W.T. Kranert, F.D. Maul, O. Schr{\"o}der, A. Karimian-Tatriz, O. Geb, R.P. Baum, U.W. Scherer}, series = {Nuclear Medicine Communications. 19 (1998)}, journal = {Nuclear Medicine Communications. 19 (1998)}, isbn = {0143-3636}, pages = {535 -- 545}, year = {1998}, language = {en} } @article{SchererJacobiCastilloetal.2009, author = {Scherer, Ulrich W. and Jacobi, M. and Castillo, J. and Foerstel, D. H.}, title = {Ultra-low-level measurements of 3H and 14C in wines and champagne / Scherer, U. W. ; Jacobi, M. ; Castillo, J. ; Foerstel, D. H.}, series = {Radiation effects and defects in solids. 164 (2009), H. 5-6}, journal = {Radiation effects and defects in solids. 164 (2009), H. 5-6}, isbn = {1042-0150}, pages = {382 -- 385}, year = {2009}, language = {en} } @article{SchererKratzGoberetal.1992, author = {Scherer, Ulrich W. and Kratz, J. V. and Gober, M. K. and Zimmermann, H. P.}, title = {New nuclide 263 105 / J.V. Kratz, M.K. Gober, H.P. Zimmermann, M. Sch{\"a}del, W. Br{\"u}chle, E. Schimpf, K.E. Gregorich, A. T{\"u}rler, N.J. Hannink, K.R. Czerwinski, B. Kadkhodayan, D.M. Lee, M.J. Nurmia, D.C. Hoffman, H. G{\"a}ggeler, D. Jost, U.W. Scherer, A. Weber}, series = {Physical Review C . 45 (1992)}, journal = {Physical Review C . 45 (1992)}, pages = {1064 -- 1069}, year = {1992}, language = {en} } @article{SchererKratzSchaedeletal.1988, author = {Scherer, Ulrich W. and Kratz, J. V. and Sch{\"a}del, M. and Br{\"u}chle, W.}, title = {Lawrencium Chemistry: No Evidence for Oxidation States Lower than 3+ in Aqueous Solution / U.W. Scherer, J.V. Kratz, M. Sch{\"a}del, W. Br{\"u}chle, K.E. Gregorich, R.A. Henderson, D. Lee, M. Nurmia, D.C. Hoffman}, series = {Inorganica Chimica Acta. 146 (1988)}, journal = {Inorganica Chimica Acta. 146 (1988)}, isbn = {0020-1693}, pages = {249 -- 254}, year = {1988}, language = {en} } @article{SchererKratzZimmermannetal.1989, author = {Scherer, Ulrich W. and Kratz, J. V. and Zimmermann, H. P. and Sch{\"a}del, M.}, title = {Chemical Properties of Element 105 in Aqueous Solutions: Halide Complex Formation and Anion Exchange into Triisooctylamine / J.V. Kratz, H.P. Zimmermann, U.W. Scherer, M. Sch{\"a}del, W. Br{\"u}chle, K.E. Gregorich, C.M. Gannett, H.L. Hall, R.A. Henderson, D.M. L}, series = {Radiochimica Acta. 48 (1989)}, journal = {Radiochimica Acta. 48 (1989)}, isbn = {0033-8230}, pages = {121}, year = {1989}, language = {en} } @article{SchererSantanaMaieretal.2009, author = {Scherer, Ulrich W. and Santana, H. H. S. and Maier, G. and Rodenas, J.}, title = {Analysis of mechanical strength in ceramic pellets of nuclear fuel / Santana, H. H. S. ; Maier, G. ; Scherer, U. W. ; Rodenas, J.}, series = {Radiation effects and defects in solids. 164 (2009), H. 5-6}, journal = {Radiation effects and defects in solids. 164 (2009), H. 5-6}, publisher = {Taylor \& Francis}, address = {London}, isbn = {1042-0150}, pages = {313 -- 318}, year = {2009}, language = {en} } @article{SchererSchaedelBruechleetal.1989, author = {Scherer, Ulrich W. and Sch{\"a}del, M. and Br{\"u}chle, W. and J{\"a}ger, E.}, title = {ARCA II - A New Apparatus for Fast Repetitive HPLC-Separations / M. Sch{\"a}del, W. Br{\"u}chle, E. J{\"a}ger, E. Schimpf, J.V. Kratz, U.W. Scherer, H.P. Zimmermann}, series = {Radiochimica Acta. 48 (1989)}, journal = {Radiochimica Acta. 48 (1989)}, isbn = {0033-8230}, pages = {171}, year = {1989}, language = {en} }