@article{MedlinLangeBaumann1994,
  author    = {Medlin, L. K. and Lange, M. and Baumann, Marcus},
  title     = {Genetic differentiation among three colony-forming species of Phaeocystis : further evidence for the phylogeny of the Prymnesiophyta},
  series = {Phycologia},
  volume    = {Vol. 33},
  journal   = {Phycologia},
  number    = {Iss. 3},
  issn      = {0031-8884},
  pages     = {199 -- 212},
  year      = {1994},
  language  = {en}
}
@incollection{MedlinBarkerBaumannetal.1994,
  author    = {Medlin, L. K. and Barker, G. L. A. and Baumann, Marcus and Hayes, P. K.},
  title     = {Molecular biology and systematics},
  series = {The Haptophyte Algae (Special volume / Systematics Association : 51)},
  booktitle = {The Haptophyte Algae (Special volume / Systematics Association : 51)},
  publisher = {Clarendon Press},
  address   = {Oxford},
  isbn      = {0-19-857772-9},
  pages     = {393 -- 411},
  year      = {1994},
  language  = {en}
}
@article{MayerHentschkeHageretal.2017,
  author    = {Mayer, Jan and Hentschke, Reinhard and Hager, Jonathan and Hojdis, Nils and Karimi-Varnaneh, Hossein Ali},
  title     = {A Nano-Mechanical Instability as Primary Contribution to Rolling Resistance},
  series = {Scientific Reports},
  volume    = {7},
  journal   = {Scientific Reports},
  number    = {Article number 11275},
  publisher = {Springer},
  address   = {Berlin},
  issn      = {2045-2322},
  year      = {2017},
  language  = {en}
}
@article{MatoniBerndt1980,
  author    = {Matoni, Georg and Berndt, Heinz},
  title     = {Thermal synthesis of the optical pure pentapeptide derivative Z-(L)-Ala-(L)-Phe-Gly-(L)-Phe-Gly-OMe},
  series = {Tetrahedron letters},
  volume    = {21},
  journal   = {Tetrahedron letters},
  number    = {1},
  issn      = {0040-4039},
  doi       = {10.1016/S0040-4039(00)93618-9},
  pages     = {37 -- 40},
  year      = {1980},
  language  = {en}
}
@article{MartinsBlaserFeliksetal.2011,
  author    = {Martins, Berta M. and Blaser, Martin and Feliks, Mikolaj and Ullmann, Matthias G. and Buckel, Wolfgang and Selmer, Thorsten},
  title     = {Structural basis for a Kolbe-type decarboxylation catalyzed by a glycyl radical enzyme},
  series = {Journal of the American Chemical Society},
  journal   = {Journal of the American Chemical Society},
  publisher = {ACS Publications},
  address   = {Washington, DC},
  pages     = {1 -- 33},
  year      = {2011},
  language  = {en}
}
@article{MartinezJakobTuetal.2013,
  author    = {Martinez, Ronny and Jakob, Felix and Tu, Ran and Siegert, Petra and Maurer, Karl-Heinz and Schwaneberg, Ulrich},
  title     = {Increasing activity and thermal resistance of Bacillus gibsonii alkaline protease (BgAP) by directed evolution},
  series = {Biotechnology and bioengineering},
  volume    = {Vol. 110},
  journal   = {Biotechnology and bioengineering},
  number    = {Iss. 3},
  publisher = {Wiley},
  address   = {Weinheim},
  issn      = {1097-0290 (E-Journal); 0006-3592 (Print); 0368-1467 (Print)},
  pages     = {711 -- 720},
  year      = {2013},
  language  = {en}
}
@article{MangRoosenAnsorgeSchumacheretal.2007,
  author    = {Mang, Thomas and Roosen, Christoph and Ansorge-Schumacher, Marion and Leitner, Walter},
  title     = {Gaining pH-control in water/carbon dioxide biphasic systems / Roosen, Christoph ; Ansorge-Schumacher, Marion ; Mang, Thomas ; Leitner, Walter ; Greiner, Lasse},
  series = {Green Chemistry. 9 (2007)},
  journal   = {Green Chemistry. 9 (2007)},
  isbn      = {1463-9262},
  pages     = {455 -- 458},
  year      = {2007},
  language  = {en}
}
@article{MangRoosenAnsorgeetal.2006,
  author    = {Mang, Thomas and Roosen, C. and Ansorge, M. and Leitner, W.},
  title     = {Gaining pH-control in water/carbon dioxide biphasic systems / Abstract No. 1038 / Roosen, Ch. ; Ansorge, M. ; Mang, Thomas ; Leitner, W. ; Greiner, L.},
  series = {Green solvents for processes : Lake Constance, Friedrichshafen, Germany, 8 - 11 October 2006 ; book of abstracts / DECHEMA e.V.},
  journal   = {Green solvents for processes : Lake Constance, Friedrichshafen, Germany, 8 - 11 October 2006 ; book of abstracts / DECHEMA e.V.},
  publisher = {DECHEMA},
  address   = {Frankfurt am Main},
  pages     = {145 S.},
  year      = {2006},
  language  = {en}
}
@article{MangKricheldorfJonte1984,
  author    = {Mang, Thomas and Kricheldorf, Hans R. and Jont{\´e}, J. Michael},
  title     = {Polylactones. 1. Copolymerizations of glycolide and \&beta-caprolactone / Kricheldorf, Hans R. ; Mang, Thomas ; Jont{\´e}, J. Michael},
  series = {Macromolecules. 17 (1984), H. 10},
  journal   = {Macromolecules. 17 (1984), H. 10},
  isbn      = {0024-9297},
  pages     = {2173 -- 2181},
  year      = {1984},
  language  = {en}
}
@article{MangKricheldorfJonte1985,
  author    = {Mang, Thomas and Kricheldorf, Hans R. and Jont{\´e}, J. Michael},
  title     = {Polylactones, 2. Copolymerization of glycolide with \&\#946;-propiolactone, \&\#967;-butyrolactone or \&\#948;-valerolactone / Kricheldorf, Hans R. ; Mang, Thomas ; Jont{\´e}, J. Michael},
  series = {Die makromolekulare Chemie. 186 (1985), H. 5},
  journal   = {Die makromolekulare Chemie. 186 (1985), H. 5},
  isbn      = {1022-1352},
  pages     = {955 -- 976},
  year      = {1985},
  language  = {en}
}
@article{MangKricheldorfAu1985,
  author    = {Mang, Thomas and Kricheldorf, Hans R. and Au, M.},
  title     = {Models of molecular evolution. 2. Stereospecificity of dipeptide syntheses by means of cyanamides and carbodiimides / Kricheldorf, Hans R. ; Au, M. ; Mang, Thomas},
  series = {International journal of peptide and protein research. 26 (1985), H. 2},
  journal   = {International journal of peptide and protein research. 26 (1985), H. 2},
  isbn      = {0300-9769},
  pages     = {149 -- 157},
  year      = {1985},
  language  = {en}
}
@article{MangKricheldorf1982,
  author    = {Mang, Thomas and Kricheldorf, Hans R.},
  title     = {13-C-NMR sequence analysis. 21. Stereoselectivity of oligopeptide syntheses / Kricheldorf, Hans R. ; Mang, Thomas},
  series = {Die makromolekulare Chemie. 183 (1982), H. 9},
  journal   = {Die makromolekulare Chemie. 183 (1982), H. 9},
  isbn      = {1022-1352},
  pages     = {2093 -- 2111},
  year      = {1982},
  language  = {en}
}
@article{MangKricheldorf1982,
  author    = {Mang, Thomas and Kricheldorf, Hans R.},
  title     = {13-C-NMR sequence analysis. 22. Stereoselectivity of the polymerization of D,L-leucine and D,L-valine N-thiocarboxy anhydrides / Kricheldorf, Hans R. ; Mang, Thomas},
  series = {Die makromolekulare Chemie. 183 (1982), H. 9},
  journal   = {Die makromolekulare Chemie. 183 (1982), H. 9},
  isbn      = {1022-1352},
  pages     = {2113 -- 2129},
  year      = {1982},
  language  = {en}
}
@article{MangKricheldorf1983,
  author    = {Mang, Thomas and Kricheldorf, Hans R.},
  title     = {Stereospecificity of peptide synthesis by means of phosphorus derivatives: a model of peptide synthesis in molecular evolution / Kricheldorf, Hans R. ; Mang, Thomas},
  series = {International Journal of Biological Macromolecules. 5 (1983), H. 5},
  journal   = {International Journal of Biological Macromolecules. 5 (1983), H. 5},
  isbn      = {0141-8130},
  pages     = {258 -- 266},
  year      = {1983},
  language  = {en}
}
@article{MangKricheldorf1981,
  author    = {Mang, Thomas and Kricheldorf, Hans R.},
  title     = {13-C-NMR Sequence Analysis 20. Stereospecificity of the polymerization of D,L-Leu-NCA and D,L-Val-NCA / Kricheldorf, Hans R. ; Mang, Thomas},
  series = {Die makromolekulare Chemie. 182 (1981), H. 11},
  journal   = {Die makromolekulare Chemie. 182 (1981), H. 11},
  isbn      = {1022-1352},
  pages     = {3077 -- 3098},
  year      = {1981},
  language  = {en}
}
@article{MangKolzMartinsetal.2006,
  author    = {Mang, Thomas and Kolz, J. and Martins, J. and Kremer, K.},
  title     = {Investigation of Elastomer Foams by Single-Sided NMR / Kolz, J. ; Martins, J. ; Kremer, K. ; Bl{\"u}mich, B. ; Mang, Thomas},
  series = {Kurzfassungen : 3. bis 6. Juli 2006, N{\"u}rnberg = Summaries / Deutsche Kautschuk Tagung, 3.7.-6.7.2006},
  journal   = {Kurzfassungen : 3. bis 6. Juli 2006, N{\"u}rnberg = Summaries / Deutsche Kautschuk Tagung, 3.7.-6.7.2006},
  publisher = {DKG, Dt. Kautschuk-Ges.},
  address   = {Frankfurt, Main},
  pages     = {33},
  year      = {2006},
  language  = {en}
}
@article{MangKolzMartinsetal.2007,
  author    = {Mang, Thomas and Kolz, J. and Martins, J. and Kremer, K.},
  title     = {Investigation of the Elastomer-Foam Production with Single-Sided NMR / Kolz, J. ; Martins, J. ; Kremer, K. ; Mang, Thomas ; Bl{\"u}mich, B.},
  series = {Kautschuk Gummi Kunststoffe. 60 (2007), H. 4},
  journal   = {Kautschuk Gummi Kunststoffe. 60 (2007), H. 4},
  isbn      = {0948-3276},
  pages     = {179 -- 183},
  year      = {2007},
  language  = {en}
}
@article{MangKolzHungeretal.2007,
  author    = {Mang, Thomas and Kolz, J. and Hunger, K. and Rath, S.},
  title     = {Investigation of self-diffusion processes in ionic hydrogels with a single-sided sensor / Kolz, J. ; Hunger, K. ; Rath, S. ; Mang, T. ; Bl{\"u}mich, B.},
  series = {Magnetic Resonance Imaging. 25 (2007), H. 4},
  journal   = {Magnetic Resonance Imaging. 25 (2007), H. 4},
  isbn      = {0730-725X},
  pages     = {566 -- 567},
  year      = {2007},
  language  = {en}
}
@article{MangKolzGogaetal.2007,
  author    = {Mang, Thomas and Kolz, J. and Goga, N. and Casanova, F.},
  title     = {Spatial localization with single-sided NMR sensors / Kolz, J. ; Goga, N. ; Casanova, F. ; Mang, T. ; Bl{\"u}mich, B.},
  series = {Applied Magnetic Resonance. 32 (2007), H. 1-2},
  journal   = {Applied Magnetic Resonance. 32 (2007), H. 1-2},
  isbn      = {0937-9347},
  pages     = {171 -- 184},
  year      = {2007},
  language  = {en}
}
@article{MangHodeniusSchmitzRodeetal.2009,
  author    = {Mang, Thomas and Hodenius, M. A. J. and Schmitz-Rode, T. and Baumann, M.},
  title     = {Absorption of 10-hydroxycamptothecin into the coat of magnetoliposomes / Hodenius, M. A. J. ; Schmitz-Rode, T. ; Baumann, M. ; Ivoanova, G. ; Wong, J. E. ; Mang, T. ; Haulena, F. ; Soenen, S. J. H. ; De Cuyper, M.},
  series = {Colloids and Surfaces A: Physicochemical and Engineering Aspects. 343 (2009), H. 1-3},
  journal   = {Colloids and Surfaces A: Physicochemical and Engineering Aspects. 343 (2009), H. 1-3},
  publisher = {Elsevier},
  address   = {Amsterdam},
  isbn      = {0927-7757},
  pages     = {20 -- 23},
  year      = {2009},
  language  = {en}
}
@article{MangHaulena1992,
  author    = {Mang, Thomas and Haulena, Friedhelm},
  title     = {Monodisperse latex particles with functional groups},
  series = {Modification of polymers : 4th Dresden Polymer Discussion ; September 22 to 25, 1992 at Gaussig / Dresden University of Technology, Department of Macromolecular Chemistry and Textile Chemistry; Institute of Polymer Technology Dresden. [Organizers: Claudia Kummerl{\"o}we ...]},
  journal   = {Modification of polymers : 4th Dresden Polymer Discussion ; September 22 to 25, 1992 at Gaussig / Dresden University of Technology, Department of Macromolecular Chemistry and Textile Chemistry; Institute of Polymer Technology Dresden. [Organizers: Claudia Kummerl{\"o}we ...]},
  publisher = {Univ.},
  address   = {Dresden},
  pages     = {68 -- 88},
  year      = {1992},
  language  = {en}
}
@article{MangHaulena1998,
  author    = {Mang, Thomas and Haulena, Friedhelm},
  title     = {Recycling of Polymeric Composites},
  series = {Invited and contributing lectures presented at the 38th Microsymposium on Recycling of Polymers : held in Prague, Czech Republic, July 14 - 17, 1997 / International Union of Pure and Applied Chemistry, Macromolecular Division. Symposium ed. J. Kahovec.},
  journal   = {Invited and contributing lectures presented at the 38th Microsymposium on Recycling of Polymers : held in Prague, Czech Republic, July 14 - 17, 1997 / International Union of Pure and Applied Chemistry, Macromolecular Division. Symposium ed. J. Kahovec.},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  pages     = {147 -- 156},
  year      = {1998},
  language  = {en}
}
@article{Mang2004,
  author    = {Mang, Thomas},
  title     = {Thermosensitive Magnetic Nanoparticles for Bioanalytical and Therapeutical Applications},
  series = {Biomedizinische Technik = Biomedical Engineering. 49 (2004), H. 2},
  journal   = {Biomedizinische Technik = Biomedical Engineering. 49 (2004), H. 2},
  isbn      = {0013-5585},
  pages     = {1006 -- 1007},
  year      = {2004},
  language  = {en}
}
@article{Mang2004,
  author    = {Mang, Thomas},
  title     = {Polymer Magnetic Particles for Isolating Biomolecules, Especially Nucleic Acids},
  series = {Biomedizinische Technik = Biomedical Engineering. 49 (2004), H. 2},
  journal   = {Biomedizinische Technik = Biomedical Engineering. 49 (2004), H. 2},
  isbn      = {0013-5585},
  pages     = {1008 -- 1009},
  year      = {2004},
  language  = {en}
}
@article{ManeaLeursOrbanetal.2011,
  author    = {Manea, Marilena and Leurs, Ulrike and Orban, Erika and Baranyai, Zsuzsa and {\"O}hlschl{\"a}ger, Peter and Marquardt, Andreas and Schulcz, Akos and Tejeda, Miguel},
  title     = {Enhanced Enzymatic Stability and Antitumor Activity of Daunorubicin-GnRH-III Bioconjugates Modified in Position 4},
  series = {Bioconjugate Chemistry},
  volume    = {22},
  journal   = {Bioconjugate Chemistry},
  number    = {7},
  publisher = {ACS},
  address   = {Washington, DC},
  isbn      = {1520-4812},
  pages     = {1320 -- 1329},
  year      = {2011},
  language  = {en}
}
@article{MaggakisKelemenBorkKayseretal.2003,
  author    = {Maggakis-Kelemen, C. and Bork, M. and Kayser, Peter and Biselli, Manfred and Artmann, Gerhard},
  title     = {Biological and mechanical quality of red blood cells cultured from human umbilical cord blood stem cells},
  series = {Medical and biological engineering and computing. 41 (2003), H. 3},
  journal   = {Medical and biological engineering and computing. 41 (2003), H. 3},
  isbn      = {0140-0118},
  pages     = {350 -- 356},
  year      = {2003},
  language  = {en}
}
@article{LuisierLempiaeinenScherbichleretal.2014,
  author    = {Luisier, Rapha{\"e}lle and Lempi{\"a}inen, Harri and Scherbichler, Nina and Braeuning, Albert and Geissler, Miriam and Dubost, Valerie and M{\"u}ller, Arne and Scheer, Nico and Chibout, Salah-Dine and Hara, Hisanori and Picard, Frank and Theil, Diethilde and Couttet, Philippe and Vitobello, Antonio and Grenet, Olivier and Grasl-Kraupp, Bettina and Ellinger-Ziegelbauer, Heidrung and Thomson, John P. and Meehan, Richard R. and Elcombe, Clifford R. and Henderson, Colin J. and Wolf, C. Roland and Schwarz, Michael and Moulin, Pierre and Terranova, Remi and Moggs, Jonathan G.},
  title     = {Phenobarbital Induces Cell Cycle Transcriptional Responses in Mouse Liver Humanized for Constitutive Androstane and Pregnane X Receptors},
  series = {Toxicological Sciences},
  volume    = {139},
  journal   = {Toxicological Sciences},
  number    = {2},
  publisher = {Oxford University Press},
  address   = {Oxford},
  issn      = {1094-2025},
  doi       = {https://doi.org/10.1093/toxsci/kfu038},
  pages     = {501 -- 511},
  year      = {2014},
  abstract  = {The constitutive androstane receptor (CAR) and the pregnane X receptor (PXR) are closely related nuclear receptors involved in drug metabolism and play important roles in the mechanism of phenobarbital (PB)-induced rodent nongenotoxic hepatocarcinogenesis. Here, we have used a humanized CAR/PXR mouse model to examine potential species differences in receptor-dependent mechanisms underlying liver tissue molecular responses to PB. Early and late transcriptomic responses to sustained PB exposure were investigated in liver tissue from double knock-out CAR and PXR (CARᴷᴼ-PXRᴷᴼ), double humanized CAR and PXR (CARʰ-PXRʰ), and wild-type C57BL/6 mice. Wild-type and CARʰ-PXRʰ mouse livers exhibited temporally and quantitatively similar transcriptional responses during 91 days of PB exposure including the sustained induction of the xenobiotic response gene Cyp2b10, the Wnt signaling inhibitor Wisp1, and noncoding RNA biomarkers from the Dlk1-Dio3 locus. Transient induction of DNA replication (Hells, Mcm6, and Esco2) and mitotic genes (Ccnb2, Cdc20, and Cdk1) and the proliferation-related nuclear antigen Mki67 were observed with peak expression occurring between 1 and 7 days PB exposure. All these transcriptional responses were absent in CARᴷᴼ-PXRᴷᴼ mouse livers and largely reversible in wild-type and CARʰ-PXRʰ mouse livers following 91 days of PB exposure and a subsequent 4-week recovery period. Furthermore, PB-mediated upregulation of the noncoding RNA Meg3, which has recently been associated with cellular pluripotency, exhibited a similar dose response and perivenous hepatocyte-specific localization in both wild-type and CARʰ-PXRʰ mice. Thus, mouse livers coexpressing human CAR and PXR support both the xenobiotic metabolizing and the proliferative transcriptional responses following exposure to PB.},
  language  = {en}
}
@article{LowisFergusonPaulssenetal.2021,
  author    = {Lowis, Carsten and Ferguson, Simon and Paulßen, Elisabeth and Hoehr, Cornelia},
  title     = {Improved Sc-44 production in a siphon-style liquid target on a medical cyclotron},
  series = {Applied Radiation and Isotopes},
  volume    = {172},
  journal   = {Applied Radiation and Isotopes},
  number    = {Art. 109675},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0969-8043},
  doi       = {10.1016/j.apradiso.2021.109675},
  year      = {2021},
  language  = {en}
}
@article{LiuSchaapBallemansetal.2017,
  author    = {Liu, Z. and Schaap, K. S. and Ballemans, L. and de Blois, E. and Rohde, M. and Paulßen, Elisabeth},
  title     = {Measurement of reaction kinetics of [177Lu]Lu-DOTA-TATE using a microfluidic system},
  series = {Dalton Transactions},
  volume    = {46},
  journal   = {Dalton Transactions},
  number    = {42},
  issn      = {1477-9234},
  doi       = {10.1039/C7DT01830D},
  pages     = {14669 -- 14676},
  year      = {2017},
  language  = {en}
}
@article{LindnerBurgerRutledgeetal.2022,
  author    = {Lindner, Simon and Burger, Ren{\´e} and Rutledge, Douglas N. and Do, Xuan Tung and Rumpf, Jessica and Diehl, Bernd W. K. and Schulze, Margit and Monakhova, Yulia},
  title     = {Is the calibration transfer of multivariate calibration models between high- and low-field NMR instruments possible? A case study of lignin molecular weight},
  series = {Analytical chemistry},
  volume    = {94},
  journal   = {Analytical chemistry},
  number    = {9},
  publisher = {ACS Publications},
  address   = {Washington, DC},
  isbn      = {1520-6882},
  doi       = {10.1021/acs.analchem.1c05125},
  pages     = {3997 -- 4004},
  year      = {2022},
  abstract  = {Although several successful applications of benchtop nuclear magnetic resonance (NMR) spectroscopy in quantitative mixture analysis exist, the possibility of calibration transfer remains mostly unexplored, especially between high- and low-field NMR. This study investigates for the first time the calibration transfer of partial least squares regressions [weight average molecular weight (Mw) of lignin] between high-field (600 MHz) NMR and benchtop NMR devices (43 and 60 MHz). For the transfer, piecewise direct standardization, calibration transfer based on canonical correlation analysis, and transfer via the extreme learning machine auto-encoder method are employed. Despite the immense resolution difference between high-field and low-field NMR instruments, the results demonstrate that the calibration transfer from high- to low-field is feasible in the case of a physical property, namely, the molecular weight, achieving validation errors close to the original calibration (down to only 1.2 times higher root mean square errors). These results introduce new perspectives for applications of benchtop NMR, in which existing calibrations from expensive high-field instruments can be transferred to cheaper benchtop instruments to economize.},
  language  = {en}
}
@article{LeursMezoOehlschlaegeretal.2012,
  author    = {Leurs, Ulrike and Mezo, Gabor and {\"O}hlschl{\"a}ger, Peter and Orban, Erika and Marquard, Andrea and Manea, Marilena},
  title     = {Design, synthesis, in vitro stability and cytostatic effect of multifunctional anticancer drug-bioconjugates containing GnRH-III as a targeting moiety},
  series = {Peptide Science},
  volume    = {98},
  journal   = {Peptide Science},
  number    = {1},
  publisher = {Wiley},
  address   = {New York, NY},
  issn      = {1097-0282},
  doi       = {10.1002/bip.21640},
  pages     = {1 -- 10},
  year      = {2012},
  abstract  = {Bioconjugates containing the GnRH-III hormone decapeptide as a targeting moiety are able to deliver chemotherapeutic agents specifically to cancer cells expressing GnRH receptors, thereby increasing their local efficacy while limiting the peripheral toxicity. However, the number of GnRH receptors on cancer cells is limited and they desensitize under continuous hormone treatment. A possible approach to increase the receptor mediated tumor targeting and consequently the cytostatic effect of the bioconjugates would be the attachment of more than one chemotherapeutic agent to one GnRH-III molecule. Here we report on the design, synthesis and biochemical characterization of multifunctional bioconjugates containing GnRH-III as a targeting moiety and daunorubicin as a chemotherapeutic agent. Two different drug design approaches were pursued. The first one was based on the bifunctional [4Lys]-GnRH-III (Glp-His-Trp-Lys-His-Asp-Trp-Lys-Pro-Gly-NH2) containing two lysine residues in positions 4 and 8, whose ϵ-amino groups were used for the coupling of daunorubicin. In the second drug design, the native GnRH-III (Glp-His-Trp-Ser-His-Asp-Trp-Lys-Pro-Gly-NH2) was used as a scaffold; an additional lysine residue was coupled to the ϵ-amino group of 8Lys in order to generate two free amino groups available for conjugation of daunorubicin. The in vitro stability/degradation of all synthesized compounds was investigated in human serum, as well as in the presence of rat liver lysosomal homogenate. Their cellular uptake was determined on human breast cancer cells and the cytostatic effect was evaluated on human breast, colon and prostate cancer cell lines. Compared with a monofunctional compound, both drug design approaches resulted in multifunctional bioconjugates with increased cytostatic effect.},
  language  = {en}
}
@article{LempiaeinenCouttetBolognanietal.2012,
  author    = {Lempi{\"a}inen, Harri and Couttet, Philippe and Bolognani, Federico and M{\"u}ller, Arne and Dubost, Val{\´e}rie and Luisier, Rapha{\"e}lle and Rio-Espinola, Alberto del and Vitry, Veronique and Unterberger, Elif B. and Thomson, John P. and Treindl, Fridolin and Metzger, Ute and Wrzodek, Clemens and Hahne, Florian and Zollinger, Tulipan and Brasa, Sarah and Kalteis, Magdalena and Marcellin, Magali and Giudicelli, Fanny and Braeuning, Albert and Morawiec, Laurent and Zamurovic, Natasa and L{\"a}ngle, Ulrich and Scheer, Nico and Sch{\"u}beler, Dirk and Goodman, Jay and Chibout, Salah-Dine and Marlowe, Jennifer and Theil, Dietlinde and Heard, David J. and Grenet, Olivier and Zell, Andreas and Templin, Markus F. and Meehan, Richard R. and Wolf, Roland C. and Elcombe, Clifford R. and Schwarz, Michael and Moulin, Pierre and Terranova, R{\´e}mi and Moggs, Jonathan G.},
  title     = {Identification of Dlk1-Dio3 imprinted gene cluster non-coding RNAs as novel candidate biomarkers for liver tumor promotion},
  series = {Toxicological Sciences},
  volume    = {131},
  journal   = {Toxicological Sciences},
  number    = {2},
  publisher = {Oxford University Press},
  address   = {Oxford},
  issn      = {1094-2025},
  doi       = {10.1093/toxsci/kfs303},
  pages     = {375 -- 386},
  year      = {2012},
  abstract  = {The molecular events during nongenotoxic carcinogenesis and their temporal order are poorly understood but thought to include long-lasting perturbations of gene expression. Here, we have investigated the temporal sequence of molecular and pathological perturbations at early stages of phenobarbital (PB) mediated liver tumor promotion in vivo. Molecular profiling (mRNA, microRNA [miRNA], DNA methylation, and proteins) of mouse liver during 13 weeks of PB treatment revealed progressive increases in hepatic expression of long noncoding RNAs and miRNAs originating from the Dlk1-Dio3 imprinted gene cluster, a locus that has recently been associated with stem cell pluripotency in mice and various neoplasms in humans. PB induction of the Dlk1-Dio3 cluster noncoding RNA (ncRNA) Meg3 was localized to glutamine synthetase-positive hypertrophic perivenous hepatocytes, sug- gesting a role for β-catenin signaling in the dysregulation of Dlk1-Dio3 ncRNAs. The carcinogenic relevance of Dlk1-Dio3 locus ncRNA induction was further supported by in vivo genetic dependence on constitutive androstane receptor and β-catenin pathways. Our data identify Dlk1-Dio3 ncRNAs as novel candidate early biomarkers for mouse liver tumor promotion and provide new opportunities for assessing the carcinogenic potential of novel compounds.},
  language  = {en}
}
@article{LawsonScheerPhametal.2001,
  author    = {Lawson, Nathan D. and Scheer, Nico and Pham, Van N. and Kim, Ceol-Hee and Chitnis, Ajay B. and Campos-Ortega, Jos{\´e} A. and Weinstein, Brant M.},
  title     = {Notch signaling is required for arterial-venous differentiation during embryonic vascular development},
  series = {Development},
  volume    = {128},
  journal   = {Development},
  number    = {19},
  issn      = {1477-9129},
  pages     = {3675 -- 3683},
  year      = {2001},
  language  = {en}
}
@misc{LauthWolfBurkhart1998,
  author    = {Lauth, Jakob and Wolf, Gerhard and Burkhart, Bernd},
  title     = {Preparation of alkoxylation products in the presence of mixed hydroxides modified with additives : United States Patent ; patent number 5,741,947 ; date of patent: Apr. 21, 1998 / assignee: BASF Aktiengesellschaft. Inventors: Gerhard Wolf ; Bernd Burkhart ; Guenter Lauth ...},
  publisher = {[United States Trademark and Patent Office]},
  address   = {[Alexandria, VA]},
  pages     = {8 S.},
  year      = {1998},
  language  = {en}
}
@misc{LauthTruebenbachHagemeyer1999,
  author    = {Lauth, Jakob and Tr{\"u}benbach, Peter and Hagemeyer, Alfred},
  title     = {Monomodal and polymodal catalyst supports and catalysts having narrow pore size distributions and their production : United States Patent ; patent number 5,935,898 ; date of patent: Aug. 10, 1999 / assignee: BASF Aktiengesellschaft. Inventors: Peter Trubenbach ; Alfred Hagemeyer ; Gunter Lauth ...},
  publisher = {[United States Patent and Trademark Office]},
  address   = {[Alexandria, VA]},
  pages     = {27 S. : graph. Darst.},
  year      = {1999},
  language  = {en}
}
@article{LauthSolomunHirschwaldetal.1989,
  author    = {Lauth, Jakob and Solomun, T. and Hirschwald, W. and Christmann, K.},
  title     = {The interaction of carbon monoxide with a ruthenium(1010) surface},
  series = {Surface Science. 210 (1989), H. 1-2},
  journal   = {Surface Science. 210 (1989), H. 1-2},
  isbn      = {0039-6028},
  pages     = {201 -- 224},
  year      = {1989},
  language  = {en}
}
@article{LauthSolomunHirschwaldetal.1989,
  author    = {Lauth, Jakob and Solomun, T. and Hirschwald, W. and Christmann, K.},
  title     = {The interaction of carbon monoxide with a ruthenium(1010) surface},
  series = {Surface Science Letters. 210 (1989), H. 1-2},
  journal   = {Surface Science Letters. 210 (1989), H. 1-2},
  isbn      = {0167-2584},
  pages     = {A74 -- A75},
  year      = {1989},
  language  = {en}
}
@misc{LauthMuellerHoelderich1994,
  author    = {Lauth, Jakob and M{\"u}ller, Ulrich and Hoelderich, Wolfgang},
  title     = {Colored crystalline aluminophosphates and/or silicoaluminophosphates of the AEL or VFI type : United States Patent ; patent number 5,360,474 ; date of patent: Nov. 1, 1994 / assignee: BASF Aktiengesellschaft},
  publisher = {[United States Trademark and Patent Office]},
  address   = {[Alexandria, VA]},
  pages     = {12 S. : Ill.},
  year      = {1994},
  language  = {en}
}
@misc{LauthMuellerHoelderich1994,
  author    = {Lauth, Jakob and M{\"u}ller, Ulrich and Hoelderich, Wolfgang},
  title     = {Preparation of aluminophosphates and silicoaluminophosphates having the AEL structure using 1,2-bis-( 4-pyridyl)-ethane : United States Patent ; patent number 5,324,493 ; date of patent: Jun. 28, 1994 / assignee: BASF Aktiengesellschaft. Inventors: Ulrich Mueller ; Wolfgang Hoelderich ; Guenter Lauth},
  publisher = {[United States Trademark and Patent Office]},
  address   = {[Alexandria, VA]},
  pages     = {6 S. : Ill.},
  year      = {1994},
  language  = {en}
}
@book{LauthHoelderichWagenblast1993,
  author    = {Lauth, Jakob and Hoelderich, Wolfgang and Wagenblast, Gerhard},
  title     = {Molecular sieves containing azo dyes ; Internationale [Pantent]anmeldung WO93/17965 ; Ver{\"o}ffentlichungsdatum: 16.09.1993 / Anmelder: BASF AG},
  publisher = {Weltorganisation f{\"u}r geistiges Eigentum, Internat. B{\"u}ro},
  address   = {[Genf]},
  pages     = {45 S.},
  year      = {1993},
  language  = {en}
}
@misc{LauthHoelderichWagenblast1996,
  author    = {Lauth, Jakob and Hoelderich, Wolfgang and Wagenblast, Gerhard},
  title     = {Molecular sieves containing azo dyes : United States Patent ; patent number 5,573,585 ; date of patent: Nov. 12, 1996 / assignee: Wolfgang Hoelderich. Inventors: Guenter Lauth ; Wolfgang Hoelderich ; Gerhard Wagenblast ...},
  publisher = {[United States Trademark and Patent Office]},
  address   = {[Alexandria, VA]},
  pages     = {15 S. : graph. Darst.},
  year      = {1996},
  language  = {en}
}
@misc{LauthHoelderichHarthetal.1996,
  author    = {Lauth, Jakob and Hoelderich, Wolfgang and Harth, Klaus and Hibst, Hartmuth},
  title     = {Coated catalysts : United States Patent ; patent number 5,559,065 ; date of patent: Sep. 24, 1996 / assignee: BASF Aktiengesellschaft},
  publisher = {[United States Trademark and Patent Office]},
  address   = {[Alexandria, VA]},
  pages     = {7 S.},
  year      = {1996},
  language  = {en}
}
@article{LauthHoelderichWagenblast1995,
  author    = {Lauth, Jakob and Hoelderich, W. and Wagenblast, G.},
  title     = {Molecular sieves containing azo dyes},
  series = {Zeolites. 15 (1995), H. 2},
  journal   = {Zeolites. 15 (1995), H. 2},
  isbn      = {0144-2449},
  pages     = {184},
  year      = {1995},
  language  = {en}
}
@article{LauthHoelderichWagenblast1995,
  author    = {Lauth, Jakob and Hoelderich, W. and Wagenblast, G.},
  title     = {Crystalline zeolites containing indigo dyes},
  series = {Zeolites. 15 (1995), H. 1},
  journal   = {Zeolites. 15 (1995), H. 1},
  isbn      = {0144-2449},
  pages     = {86},
  year      = {1995},
  language  = {en}
}
@book{LauthHarreusGoetzetal.1999,
  author    = {Lauth, Jakob and Harreus, Albrecht and G{\"o}tz, Norbert and Rang, Harald [u.a.]},
  title     = {Preparation O-(2-Hydroxyalkyl)Oximes = of Verfahren zur Herstellung von O-(2-Hydroxy)Oximen : Europ{\"a}ische Patentschrift EP0775107B1 ; Ver{\"o}ffentlichungstag im Patentblatt: 18.11.1999 / Anmelder: BASF AG, 67063 Ludwigshafen. Erfinder: Albrecht Harreus ; Norbert G{\"o}tz ; Harald Rang ... G{\"u}nter Lauth},
  publisher = {Europ{\"a}isches Patentamt},
  address   = {[M{\"u}nchen u.a.]},
  pages     = {8 S. : graph. Darst.},
  year      = {1999},
  language  = {en}
}
@misc{LauthHarreusGoetzetal.1997,
  author    = {Lauth, Jakob and Harreus, Albrecht and Goetz, Norbert and Rang, Harald},
  title     = {Preparation of O-(2-hydroxyalkyl) oximes : [South African Patent ] publication number: ZA9506402 ; publication date: 1997-02-03 / applicant: BASF AG. Inventor: Harreus, Albrecht ; Goetz, Norbert ; Rang, Harald .... Lauth, Guenter ...},
  publisher = {[South African Companies and Intellectual Property Registration Office]},
  address   = {[Pretoria]},
  year      = {1997},
  language  = {en}
}
@misc{LauthHagemeyerLautensacketal.1999,
  author    = {Lauth, Jakob and Hagemeyer, Alfred and Lautensack, Thomas and Deimling, Axel},
  title     = {Catalyst and catalytic oxidative dehydrogenation of alkylaromatics and paraffins : United States Patent ; patent number 5,902,918 ; date of patent: May 11, 1999 / Assignee: BASF Aktiengesellschaft. Inventors: Alfred Hagemeyer ; Gunter Lauth ; Thomas Lautensack ; Axel Deimling},
  publisher = {United States Trademark and Patent Office},
  address   = {[Alexandria, VA]},
  pages     = {6 S.},
  year      = {1999},
  language  = {en}
}
@misc{LauthDingerdissenTruebenbachetal.1997,
  author    = {Lauth, Jakob and Dingerdissen, Uwe and Tr{\"u}benbach, Peter and Steuerle, Ulrich},
  title     = {Preparation of aziridines : United States Patent ; patent number 5,693,825 ; date of patent: Dec. 2, 1997 / assignee: BASF Aktiengesellschaft. Inventors: Uwe Dingerdissen ; Gunter Lauth ; Peter Trubenbach ; Ulrich Steuerle},
  publisher = {United States Patent and Trademark Office},
  address   = {[Alexandria, VA]},
  pages     = {6 S. : Ill.},
  year      = {1997},
  language  = {en}
}
@book{LauthDingerdissenSteuerle1996,
  author    = {Lauth, Jakob and Dingerdissen, Uwe and Steuerle, Ulrich},
  title     = {Cup catalyst and process for producing aziridines : [Internationale Pantentanmeldung WO9633018] ; Ver{\"o}ffentlichungsdatum: 1996-10-24 / Anmelder: BASF AG ; Dingerdissen, Uwe ; Lauth, Guenther ; Steuerle, Ulrich. Erfinder: Dingerdissen, Uwe ; Lauth, Guenther ; Steuerle, Ulrich},
  publisher = {[Weltorganisation f{\"u}r geistiges Eigentum]},
  address   = {[Genf]},
  year      = {1996},
  language  = {en}
}
@misc{LauthDingerdissenHenne1998,
  author    = {Lauth, Jakob and Dingerdissen, Uwe and Henne, Andreas},
  title     = {Preparation of amines : United States Patent ; patent number 5,817,871 ; date of patent: Oct. 6, 1998 / Assignee: BASF Aktiengesellschaft. Inventors: Uwe Dingerdissen ; Gunter Lauth ; Andreas Henne ....},
  publisher = {[United States Trademark and Patent Office]},
  address   = {[Alexandria, VA]},
  pages     = {6 S. : Ill.},
  year      = {1998},
  language  = {en}
}