@techreport{BirmansTamborninoUllrich2024, type = {Working Paper}, author = {Birmans, Katrin and Tambornino, Philipp and Ullrich, Anna Valentine}, title = {Bevor Sie Coscine nutzen - Handreichung f{\"u}r Forschende an HAW}, doi = {10.5281/zenodo.12158546}, pages = {2 Seiten}, year = {2024}, abstract = {Um die Forschungsdatenmanagement-Plattform Coscine optimal f{\"u}r Forschungsprojekte nutzen zu k{\"o}nnen, ist es sinnvoll, einige Fragen im Vorhinein zu kl{\"a}ren. So k{\"o}nnen aufwendige {\"A}nderungen der Datenverwaltung im Nachhinein vermieden werden. Hierzu bietet die Handreichung hilfreiche Leitfragen und Erl{\"a}uterungen f{\"u}r Forschende und FDM-Service-Personal an HAW in NRW (DH.NRW-Hochschulen). FDM-Service-Mitarbeitende k{\"o}nnen die Handreichung in ihrer Beratung zu Coscine einsetzen und mit der Eingabemaske in der Kopfzeile des Dokuments auf ihre Hochschule anpassen.}, language = {de} } @misc{WiesenTippkoetterMuffleretal.2012, author = {Wiesen, S. and Tippk{\"o}tter, Nils and Muffler, K. and Sohling, U. and Ruf, F. and Ulber, Roland}, title = {Nutzung von Rohglycerin: Rohglycerin-Aufarbeitung, Herstellung von 1, 3-Propandiol und R{\"u}ckgewinnung von Fetts{\"a}uren}, series = {Chemie Ingenieur Technik}, volume = {84}, journal = {Chemie Ingenieur Technik}, number = {8}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {0009-286X}, doi = {10.1002/cite.201250265}, pages = {1296}, year = {2012}, abstract = {Die fermentative Verwertung von Rohglycerin setzt je nach Herstellungsmethode und Produktionsorganismus eine Vorbehandlung des Glycerins zur Entfernung von Produktinhibitoren voraus. Durch den Einsatz von Hydrotalcit-Adsorbern k{\"o}nnen die im Rohglycerin enthaltenen Fetts{\"a}uren entfernt werden. Durch diese einfache Aufarbeitungsmethode ist ein mit reinem Glycerin vergleichbarer Umsatz von stark mit Fetts{\"a}uren verunreinigtem Rohglycerin zu 1,3-Propandiol (PDO) m{\"o}glich. Die durch den Hydrotalcit gebundenen Fetts{\"a}uren lassen sich mit einem Ethanol-Wasser-Gemisch eluieren. Somit kann der Adsorber regeneriert und die Fetts{\"a}uren wieder der Wertsch{\"o}pfungskette zugef{\"u}hrt werden. Im Fed-Batch-Experiment kann mit C. diolis eine PDO-Konzentration von {\"u}ber 50 g L⁻¹ unter Verwendung des aufgereinigten Rohglycerins erzielt werden. In der industriellen Produktion wird PDO momentan destillativ aufgearbeitet. Ein adsorptives Aufarbeitungsverfahren kann den Energiebedarf des Herstellungsprozesses drastisch senken. Auf der Suche nach einem geeigneten Material wurde ein Adsorberscreening in Bezug auf die Bindungseigenschaften durchgef{\"u}hrt. Mit einem b-Zeolith der Firma S{\"u}d ChemieAG konnte bisher die h{\"o}chste Beladung im Modellsystem von 120 mg PDO/gAdsorber erreicht werden.}, language = {de} } @misc{TippkoetterMaurerPasteuretal.2010, author = {Tippk{\"o}tter, Nils and Maurer, S. and Pasteur, A. and Kampeis, P. and Ulber, Roland}, title = {Hochgradient-Magnetseparation von Fermentationsprodukten-FEM Simulation der Filtermatrix}, series = {Chemie Ingenieur Technik}, volume = {82}, journal = {Chemie Ingenieur Technik}, number = {9}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {0009-286X}, doi = {10.1002/cite.201050217}, pages = {1361}, year = {2010}, abstract = {Durch den Einsatz magnetisierbarer Partikel lassen sich Stoffwechselprodukte direkt und selektiv aus feststoffreichen Fermentationssuspensionen abtrennen. Im Gegensatz zu klassischen Adsorbermaterialien k{\"o}nnen magnetisierbare Partikel mit sehr geringen Durchmessern verwendet werden. Zur deren Abtrennung ist jedoch ein hoher Magnetfeldgradient notwendig. Dieser wird in der Regel durch in der Trennkammer bzw. dem Magnetfeld eingebrachte magnetisierbare Dr{\"a}hte realisiert. Bei der Auslegung der Drahtgitter ist ein Kompromiss zwischen Abtrennrate und Durchl{\"a}ssigkeit n{\"o}tig. Die Ausrichtung der Dr{\"a}hte in Relation zum Magnetfeld, deren Abstand sowie die geometrische Anordnung k{\"o}nnen hierbei variiert werden. Zum Verst{\"a}ndnis der Einfl{\"u}sse auf das sich ausbildende Magnetfeld und die Fluiddynamik wurden Simulationen mit der Finite-Elemente-Methode durchgef{\"u}hrt und experimentell {\"u}berpr{\"u}ft. Hierf{\"u}r wurden die Dr{\"a}hte unter Variation von Anzahl, Richtung und Anordnung in den Hochgradient-Magnetseparator eingebracht. Erste Verifizierungen der Simulationen zeigen, dass die in Magnetfeldrichtung ausgerichteten Dr{\"a}hte (x-Achse) {\"u}ber die geringste Partikelr{\"u}ckhaltef{\"a}higkeit verf{\"u}gen. Die Dr{\"a}hte der y- und z-Achse halten den gr{\"o}ßten Anteil der Magnetpartikel zur{\"u}ck, wobei die Dr{\"a}hte in y-Richtung den h{\"o}chsten Feldgradienten ausbilden. Des Weiteren konnte gezeigt werden, dass eine rhomboedrische Drahtanordnung der kubischen vorzuziehen ist.}, language = {de} } @misc{AlKaidyUlberTippkoetter2014, author = {Al-Kaidy, Huschyar and Ulber, Roland and Tippk{\"o}tter, Nils}, title = {Eine Plattform-Technologie f{\"u}r die automatisierte Reaktionsf{\"u}hrung in magnetisierbaren mikrofluidischen Tropfen}, series = {Chemie Ingenieur Technik}, volume = {86}, journal = {Chemie Ingenieur Technik}, number = {9}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {0009-286X}, doi = {10.1002/cite.201450424}, pages = {1419 -- 1420}, year = {2014}, abstract = {{\"U}blicherweise werden biotechnologische Reaktionssysteme im mikrofluidischen Maßstab in vorstrukturierten Bauteilen oder mit auf Wellplatten basierenden Robotersystemen realisiert. In dem hier vorgestellten System werden chemische oder biologische Reaktionen mit magnetischen Mikroreaktoren (MR) durchgef{\"u}hrt, bei denen hydrophobe magnetische Mikropartikel einen w{\"a}ssrigen Kern umschließen. Solche MR bieten eine gute Kontrolle der Reaktionsbedingungen, eine verbesserte Sicherheit und Portabilit{\"a}t. Die neue Plattformtechnologie erm{\"o}glicht die zweidimensionale Bewegung der magnetischen MR auf einer planaren Ebene. Oberhalb oder unterhalb der Plattform werden Magnetfeldgradienten zum Manipulieren und Bewegen eines oder mehrerer magnetischer MR erzeugt. Die optimal auf die MR wirkenden magnetischen Kr{\"a}fte werden experimentell ermittelt und simuliert. Die Aktivierung der Magnetfelder wird automatisiert durch elektrische Spulen mit Eisenkern bzw. Neodymmagnet gesteuert. Angewendet wurde das System beim reversiblen {\"O}ffnen von MR, um z. B. Reaktionspartner in den w{\"a}ssrigen Kern zu injizieren oder Proben zu entnehmen. Ferner wurde Lac-case A und b-Glucosidase auf einer Quarzglasoberfl{\"a}che immobilisiert und mit einem MR zum Reagieren gebracht. Weiterhin wurden MR fusioniert und so ein w{\"a}ssriger Kern bestehend aus Laccase mit einem aus dem entsprechenden Substrat Syringaldazin vereint.}, language = {de} } @misc{WollnyStadtmuellerTippkoetteretal.2012, author = {Wollny, S. and Stadtm{\"u}ller, R. and Tippk{\"o}tter, Nils and Oster, J. and Kampeis, P. and Ulber, Roland}, title = {Optimierung der selektiven Aufarbeitung von Proteinen mit Aptamer-funktionalisierten Magnetpartikeln}, series = {Chemie Ingenieur Technik}, volume = {84}, journal = {Chemie Ingenieur Technik}, number = {8}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {0009-286X}, doi = {10.1002/cite.201250031}, pages = {1203}, year = {2012}, abstract = {Die Herstellung pharmakologisch relevanter Proteine durch Mikroorganismen f{\"u}hrt eine mehrstufige Aufarbeitung mit sich. Durch die Verwendung von Aptameren, kurzen einzelstr{\"a}ngigen DNA- oder RNA-Oligonukleotiden immobilisiert auf funktionalisierten, wiederverwendbaren Magnetpartikeln, k{\"o}nnen mehrere dieser Abtrennungsoperationen kombiniert und damit die Prozesskosten minimiert werden. Aufgrund der definierten dreidimensionalen Struktur k{\"o}nnen Aptamere kleine organische Molek{\"u}le hochspezifisch binden. Im vorgestellten Projekt wird die Aufarbeitung von His6-GFP als Modellprotein mithilfe der mit Aptamer funktionalisierten Magnetpartikel durchgef{\"u}hrt. In bisherigen Versuchen wurde die Bindung von Aptameren auf den magnetischen Partikeln sowie die Bindung des Modellproteins GFP auf den Partikeln optimiert. Des Weiteren wurden mehrere Strategien zur Elution des GFPs von den Partikeln verfolgt, um den Proteinertrag zu maximieren und die Partikel rezyklieren zu k{\"o}nnen. Die Untersuchung unspezifischer Bindungen von Zelltr{\"u}mmern und Proteinen an die Magnetpartikel wurde mithilfe eines konfokalen Laser-Scanning-Mikroskops durchgef{\"u}hrt.}, language = {de} } @misc{SiekerTippkoetterMuffleretal.2012, author = {Sieker, T. and Tippk{\"o}tter, Nils and Muffler, K. and Ulber, Roland}, title = {Herstellung von Ethanol, Phenols{\"a}uren, organischen S{\"a}uren und Biogas durch vollst{\"a}ndige Nutzung von Grassilage in einer Bioraffinerie}, series = {Chemie Ingenieur Technik}, volume = {84}, journal = {Chemie Ingenieur Technik}, number = {8}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {0009-286X}, doi = {10.1002/cite.201250415}, pages = {1297}, year = {2012}, abstract = {Gr{\"a}ser sind in der Lage, einen großen Teil der f{\"u}r eine biobasierte Wirtschaft ben{\"o}tigten Biomasse zur Verf{\"u}gung zustellen. Um eine ganzj{\"a}hrige Nutzung des Grases zu gew{\"a}hrleisten, muss eine stabile Lagerung des Grases erreicht werden, was z. B. durch Silieren m{\"o}glich ist. Die konservierende Wirkung der Silierung beruht auf der Bildung organischer S{\"a}uren. Um diese zu gewinnen, wird die Silage gepresst, die organischen S{\"a}uren {\"u}ber Fl{\"u}ssig/Fl{\"u}ssig-Extraktion aus dem Presssaft abgetrenntund mittels chromatographischer Methoden weiter aufgereinigt. Im pr{\"a}sentierten Konzept werden die im Presskuchen enthaltenen Lignocellulosen hydrolysiert und die erhaltenen Monosaccharide zu Ethanol fermentiert. Die Phenols{\"a}uren, die in Gr{\"a}sern die Rolle des Lignins {\"u}bernehmen, k{\"o}nnen simultan mit der Hydrolyse der Polysaccharide enzymatisch abgetrennt und als Nebenprodukt gewonnen werden. Die nach der Abtrennung des Ethanols verbleibenden Fermentationsreststoffe werden f{\"u}r die Herstellung von Biogas verwendet.}, language = {de} } @misc{SiekerTippkoetterUlberetal.2010, author = {Sieker, T. and Tippk{\"o}tter, Nils and Ulber, Roland and Bart, Hans-J{\"o}rg and Heinzle, E.}, title = {Gr{\"u}ne Bioraffinerie: Ganzheitliche Nutzung von Grassilage f{\"u}r die Herstellung von Grund-und Feinchemikalien}, series = {Chemie Ingenieur Technik}, volume = {82}, journal = {Chemie Ingenieur Technik}, number = {9}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {0009-286X}, doi = {10.1002/cite.201050321}, pages = {1564}, year = {2010}, abstract = {Gras hat ein hohes Potenzial als nachwachsender Rohstoff. Bei ungeeigneter Lagerung verderben Gr{\"a}ser allerdings innerhalb weniger Tage. Dieser Nachteil kann durch die Silierung des Grasschnittes behoben werden. Eines der wichtigsten in der Silage enthaltenen Produkte ist die Milchs{\"a}ure. Um diese f{\"u}r weitere Aufarbeitungsschritte zug{\"a}nglich zu machen, wird aus der Silage ein Presssaft hergestellt. Die Milchs{\"a}ure wird aus einem Silagepresssaft mittels Extraktion durch ionische Fl{\"u}ssigkeiten isoliert. Dabei wird zum einen eine reine Milchs{\"a}ure hergestellt, die z. B. f{\"u}r die Herstellung von Polymilchs{\"a}ure genutzt werden kann. Zum anderen wird ein weniger aufgereinigter Extrakt gewonnen, der f{\"u}r die fermentative Produktion von L-Lysin und 1,2-Propandiol genutzt werden soll. Im Rahmen des Projekts erfolgt die gentechnische Optimierung von Corynebacterium glutamicum f{\"u}r die Umsetzung von Milchs{\"a}urezu L-Lysin. Die im nach der Pressung verbleibenden Presskuchen enthaltenen Grasfasern bestehen zu einem großen Teil aus Polysacchariden. Diese werden hydrolysiert und die dabei freigesetzten Zucker zu Grundchemikalien wie Ethanol oder Itakons{\"a}ure fermentiert. Im Rahmen einer vollst{\"a}ndigen Nutzung der Silage wird das Raffinat aus der Milchs{\"a}ureextraktion als Mediumsupplement in der Fermentation eingesetzt, was die Zugabe weiterer Medienbestandteile {\"u}berfl{\"u}ssig macht. Die R{\"u}ckst{\"a}nde der Hydrolysen und Fermentationen sollen dar{\"u}berhinaus f{\"u}r die Herstellung von Biogas genutzt werden.}, language = {de} } @article{BiewendtBoehnertBlaschke2020, author = {Biewendt, Marcel and B{\"o}hnert, Arno and Blaschke, Florian}, title = {The repercussions of the digital twin in the automotive industry on the new marketing logic}, series = {European Journal of Marketing and Economics}, volume = {4}, journal = {European Journal of Marketing and Economics}, number = {1}, publisher = {Revistia}, address = {London}, issn = {2601-8659}, doi = {10.26417/229eim64f}, pages = {68 -- 73}, year = {2020}, abstract = {Rapid development of virtual and data acquisition technology makes Digital Twin Technology (DT) one of the fundamental areas of research, while DT is one of the most promissory developments for the achievement of Industry 4.0. 48\% percent of organisations implementing the Internet of Things are already using DT or plan to use DT in 2020. The global market for DT is expected to grow by 38 percent annually, reaching USD16 billion by 2023. In addition, the number of participating organisations using digital twins is expected to triple by 2022. DTs are characterised by the integration between physical and virtual spaces. The driving idea for DT is to develop, test and build our devices in a virtual environment. The objective of this paper is to study the impact of DT in the automotive industry on the new marketing logic. This paper outlines the current challenges and possible directions for the future DT in marketing. This paper will be helpful for managers in the industry to use the advantages and potentials of DT.}, language = {en} } @article{BoehnertBlaschkeBiewendt2023, author = {B{\"o}hnert, Arno and Blaschke, Florian and Biewendt, Marcel}, title = {Impact of sustainability on the strategic direction of luxury companies}, series = {European Journal of Marketing and Economics}, volume = {6}, journal = {European Journal of Marketing and Economics}, number = {1}, publisher = {Revistia}, address = {London}, issn = {2601-8659}, pages = {70 -- 85}, year = {2023}, abstract = {Today's society is undergoing a paradigm shift driven by the megatrend of sustainability. This undeniably affects all areas of Western life. This paper aims to find out how the luxury industry is dealing with this change and what adjustments are made by the companies. For this purpose, interviews were conducted with managers from the luxury industry, in which they were asked about specific measures taken by their companies as well as trends in the industry. In a subsequent evaluation, the trends in the luxury industry were summarized for the areas of ecological, social, and economic sustainability. It was found that the area of environmental sustainability is significantly more focused than the other sub-areas. Furthermore, the need for a customer survey to validate the industry-based measures was identified.}, language = {en} } @incollection{Golland2024, author = {Golland, Alexander}, title = {Kommentierung von \S\S 6 bis 10 EKD-Datenschutzgesetz}, series = {EKD-Datenschutzgesetz. Datenschutzbestimmungen der evangelischen Kirche}, booktitle = {EKD-Datenschutzgesetz. Datenschutzbestimmungen der evangelischen Kirche}, editor = {Wagner, Ralph}, publisher = {Nomos}, address = {Baden-Baden}, isbn = {978-3-8487-8111-9}, pages = {153 -- 228}, year = {2024}, language = {de} } @misc{GraesslRenzHezeletal.2012, author = {Gr{\"a}ßl, Andreas and Renz, Wolfgang and Hezel, Fabian and Frauenrath, Tobias and Pfeiffer, Harald and Hoffmann, Werner and Kellmann, Peter and Martin, Conrad and Niendorf, Thoralf}, title = {Design, evaluation and application of a modular 32 channel transmit/receive surface coil array for cardiac MRI at 7T}, series = {2012 ISMRM Annual Meeting Proceedings}, journal = {2012 ISMRM Annual Meeting Proceedings}, issn = {1545-4428}, year = {2012}, abstract = {Cardiac MR (CMR) at ultrahigh (≥7.0 T) fields is regarded as one of the most challenging MRI applications. At 7.0 T image quality is not always exclusively defined by signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR). Detrimental effects bear the potential to spoil the signal-to-noise (SNR) and contrast-to-noise (CNR) benefits of cardiac MR (CMR) at 7.0 T. B₁⁺-inhomogeneities and signal voids represent the main challenges. Various pioneering coil concepts have been proposed to tackle these issues, enabling cardiac MRI at 7.0 T. This includes a trend towards an ever larger number of transmit and receive channels. This approach affords multi-dimensional B₁⁺ modulations to improve B₁⁺ shimming performance and to enhance RF efficiency. Also, parallel imaging benefits from a high number of receive channels enabling two-dimensional acceleration. Realizing the limitations of existing coil designs tailored for UHF CMR and recognizing the opportunities of a many element TX/RX channel architecture this work proposes a modular, two dimensional 32-channel transmit and receive array using loop elements and examines its efficacy for enhanced B¹+ homogeneity and improved parallel imaging performance.}, language = {en} } @incollection{HarlacherAltepostElsenetal.2024, author = {Harlacher, Markus and Altepost, Andrea and Elsen, Ingo and Ferrein, Alexander and Hansen-Ampah, Adjan and Merx, Wolfgang and Niehues, Sina and Schiffer, Stefan and Shahinfar, Fatemeh Nasim}, title = {Approach for the identification of requirements on the design of AI-supported work systems (in problem-based projects)}, series = {AI in Business and Economics}, booktitle = {AI in Business and Economics}, editor = {Lausberg, Isabel and Vogelsang, Michael}, publisher = {De Gruyter}, address = {Berlin}, isbn = {9783110790320}, doi = {10.1515/9783110790320}, pages = {87 -- 99}, year = {2024}, abstract = {To successfully develop and introduce concrete artificial intelligence (AI) solutions in operational practice, a comprehensive process model is being tested in the WIRKsam joint project. It is based on a methodical approach that integrates human, technical and organisational aspects and involves employees in the process. The chapter focuses on the procedure for identifying requirements for a work system that is implementing AI in problem-driven projects and for selecting appropriate AI methods. This means that the use case has already been narrowed down at the beginning of the project and must be completely defined in the following. Initially, the existing preliminary work is presented. Based on this, an overview of all procedural steps and methods is given. All methods are presented in detail and good practice approaches are shown. Finally, a reflection of the developed procedure based on the application in nine companies is given.}, language = {en} } @article{FrauenrathNiendorfKob2008, author = {Frauenrath, Tobias and Niendorf, Thoralf and Kob, Malte}, title = {Acoustic method for synchronization of Magnetic Resonance Imaging (MRI)}, series = {Acta Acustica}, volume = {94}, journal = {Acta Acustica}, number = {1}, publisher = {Hirzel}, address = {Stuttgart}, issn = {1861-9959}, doi = {10.3813/AAA.918017}, pages = {148 -- 155}, year = {2008}, abstract = {Magnetic Resonance Imaging (MRI) of moving organs requires synchronization with physiological motion or flow, which dictate the viable window for data acquisition. To meet this challenge, this study proposes an acoustic gating device (ACG) that employs acquisition and processing of acoustic signals for synchronization while providing MRI compatibility, immunity to interferences with electro-magnetic and acoustic fields and suitability for MRI at high magnetic field strengths. The applicability and robustness of the acoustic gating approach is examined in a pilot study, where it substitutes conventional ECG-gating for cardiovascular MR. The merits and limitations of the ACG approach are discussed. Implications for MR imaging in the presence of physiological motion are considered including synchronization with other structure- or motion borne sounds.}, language = {en} } @masterthesis{Russo2024, type = {Bachelor Thesis}, author = {Russo, Jessica Rose}, title = {Ein lebendiger Ort : Eindr{\"u}cke aus dem Gemeinschaftsgarten HirschGr{\"u}n}, publisher = {FH Aachen}, address = {Aachen}, pages = {95 Seiten}, year = {2024}, abstract = {Die interaktive Dokumentation erz{\"a}hlt die sinnliche Wirkung des Gemeinschaftsgartens HirschGr{\"u}n und teilt die Erfahrungen von vier G{\"a}rtner:innen in einer auditiven und visuellen Auseinandersetzung, innerhalb eines Open-World Ansatzes. Das Projekt stellt eine progressive Weise dar, sich mit journalistischen Inhalten zu besch{\"a}ftigen. Es schafft Perspektiven f{\"u}r die sozialen und sch{\"o}pferischen Potenziale eines Gemeinschaftsgartens. Interaktionen, visuelle und auditive Reize illustrieren die Atmosph{\"a}re. Gr{\"u}nfl{\"a}chen sind nicht nur klimarelevant, sondern schaffen f{\"u}r Stadtbewohner:innen vielf{\"a}ltige Wege, mit Leben in Kontakt zu treten. Besonders jene verbinden Gemeinschaft, Natur und Nachhaltigkeit. Die explorative Art technischer Informationsvermittlung und aktuelle Themen dieser Zeit werden auf einer Webseite vereint. Das Projekt zeigt eine Aussicht, multimedialen Journalismus zu gestalten.}, language = {de} } @incollection{LinkeHaertschHoffmannetal.1997, author = {Linke, David-Michael and Haertsch, P. and Hoffmann, Christoph P. and Lindemann, Markus}, title = {Electronic Commerce Plattformen f{\"u}r den Werkzeugmaschinenbau}, series = {Internet im Industrieg{\"u}termarketing - Status quo und Entwicklungsperspektiven am Beispiel der Schweizer Werkzeugmaschinen-Industrie / Johannes Dickel ... (Hrsg.) Thexis-Fachbericht f{\"u}r Marketing. 97,4}, booktitle = {Internet im Industrieg{\"u}termarketing - Status quo und Entwicklungsperspektiven am Beispiel der Schweizer Werkzeugmaschinen-Industrie / Johannes Dickel ... (Hrsg.) Thexis-Fachbericht f{\"u}r Marketing. 97,4}, publisher = {Thexis}, address = {St. Gallen}, isbn = {3-908545-38-2}, pages = {60 -- 85}, year = {1997}, language = {de} } @article{KotterHoffmann2002, author = {Kotter, Michael and Hoffmann, Ulrich}, title = {Simulation eines geregelten R{\"u}hrkessels mit LABVIEW / U. Hoffmann ; M. Kotter}, series = {Virtuelle Instrumente in der Praxis : Messtechnik, Automatisierung ; Begleitband zum Kongress VIP 2002 / Rahman Jamal ... (Hrsg.). - (Praxiswissen Elektronik-Industrie : Messtechnik - Automatisierung)}, journal = {Virtuelle Instrumente in der Praxis : Messtechnik, Automatisierung ; Begleitband zum Kongress VIP 2002 / Rahman Jamal ... (Hrsg.). - (Praxiswissen Elektronik-Industrie : Messtechnik - Automatisierung)}, publisher = {H{\"u}thig}, address = {Heidelberg [u.a.]}, isbn = {3-7785-2873-4}, pages = {65}, year = {2002}, language = {de} } @article{FeuerriegelMaHoffmann1990, author = {Feuerriegel, Uwe and Ma, J. and Hoffmann, Ulrich}, title = {Untersuchungen zur Rußfilterregeneration mit Hilfe von Z{\"u}ndhilfen. Ma, J.; Hoffmann, U.; Feuerriegel, U}, series = {Erd{\"o}l und Kohle - Erdgas, Brennstoff-Chemie. 43 (1990)}, journal = {Erd{\"o}l und Kohle - Erdgas, Brennstoff-Chemie. 43 (1990)}, isbn = {0014-0058}, pages = {150 -- 157}, year = {1990}, language = {de} } @book{HardtMuellerBergetal.1980, author = {Hardt, Arno and M{\"u}ller, Gerhard and Berg, Georg P. A. and Kelleter, H.-J.}, title = {Aufbau eines Plastikszintillationsz{\"a}hlers f{\"u}r den Magnetspektrographen "BIG KARL" am J{\"u}licher Zyklotron "JULIC". M{\"u}ller, Gerhard; Berg , G. P.; Hardt, A.; Kelleter, H.-J.; Martin, S.-A.; Meissburger, J.}, publisher = {Kernforschungsanlage J{\"u}lich}, address = {J{\"u}lich}, pages = {37 S.}, year = {1980}, language = {de} } @book{LinkeHaertschHoffmannetal.1997, author = {Linke, David-Michael and Haertsch, P. and Hoffmann, Christoph P. and Lindemann, Markus}, title = {Integrierte Electronic Commerce Systeme - Auswahlkriterien und Evaluation aktueller Produktangebote. Bericht BusinessMedia. 58}, publisher = {Inst. f{\"u}r Wirtschaftsinformatik}, address = {St. Gallen}, pages = {VII, 94 S. : graph. Darst.}, year = {1997}, language = {de} } @inproceedings{HardtAbdelGawadMartinetal.1975, author = {Hardt, Arno and Abdel-Gawad, A and Martin, Siegfried A. and Reich, J.}, title = {Design procedures for the Juelich QQDDQ high resolution spectrometer}, series = {Proceedings, 5th International Conference on Magnet Technology (MT-5) : Rome, Italy, April 21-25, 1975}, booktitle = {Proceedings, 5th International Conference on Magnet Technology (MT-5) : Rome, Italy, April 21-25, 1975}, pages = {45 -- 51}, year = {1975}, language = {en} } @inproceedings{FeuerriegelWittenhorstHoffmannetal.2012, author = {Feuerriegel, Uwe and Wittenhorst, Simon and Hoffmann, Ulrich and Pook, Michael}, title = {Simulation von W{\"a}rme{\"u}bertragungsprozessen}, series = {Tagungsband zur AALE-Tagung 2012 : 9. Fachkonferenz}, booktitle = {Tagungsband zur AALE-Tagung 2012 : 9. Fachkonferenz}, publisher = {Oldenbourg Industrieverlag}, address = {M{\"u}nchen}, isbn = {978-3-8356-3305-6}, pages = {127 -- 136}, year = {2012}, language = {de} } @article{HoffmannLindemannZimmermann1998, author = {Hoffmann, Christoph P. and Lindemann, Markus and Zimmermann, Hans-Dieter}, title = {Logistik-Ressourcen im World Wide Web}, series = {Wirtschaftsinformatik. Vol. 40 (1998), iss. 3}, journal = {Wirtschaftsinformatik. Vol. 40 (1998), iss. 3}, issn = {0937-6429}, pages = {245 -- 250}, year = {1998}, language = {de} } @incollection{HoffmannLindemann1999, author = {Hoffmann, Christoph P. and Lindemann, Markus}, title = {Logistik und internetbasiertes Electronic Commerce}, series = {Schweizer Logistik-Katalog : Logistik, f{\"o}rdern, lagern, verteilen. 1999}, booktitle = {Schweizer Logistik-Katalog : Logistik, f{\"o}rdern, lagern, verteilen. 1999}, publisher = {Binkert}, address = {Lauffenburg}, pages = {16 -- 19}, year = {1999}, language = {de} } @article{HardtMartinMeissburgeretal.1978, author = {Hardt, Arno and Martin, Siegfried A. and Meissburger, J{\"u}rgen and Retz, R. and Wimmer, J.}, title = {The cryopump system of the QQDDQ magnet spectrometer BIG KARL}, series = {Vacuum}, volume = {28}, journal = {Vacuum}, number = {10-11}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1879-2715 (E-Journal); 0042-207X (Print)}, doi = {10.1016/S0042-207X(78)80026-8}, pages = {483}, year = {1978}, abstract = {Cryopumps without liquid nitrogen shielding are used to provide a vacuum of 10-6 torr in the spectrometer. The vacuum system is subdivided in three sections that can be separated by valves. The first section (scattering chamber) has a volume of 60 l, two rotation transmissions with 35 cm dia and a sliding seal that allows a rotation of 160° without deteriorating the vacuum. The second section includes the vacuum chambers inside the magnets with 6 × 80 cm cross-section and a length of 1200 cm. The third section (detector box) has a volume of 4300 l and contains a moveable detector system. The gas inside the detector with a pressure of 760 torr is separated from the vacuum by a 15 μm mylar foil with an area of 300 cm2. The detector box can be valved off by a valve with the dimension of 10 × 100 cm. The layout of system is given. The instrumentation and the interlock system are described. First experiences with this system are presented.}, language = {en} } @article{BergDemarteauHardtetal.1982, author = {Berg, Georg P. A. and Demarteau, M. and Hardt, Arno and H{\"u}rlimann, Werner and Martin, Siegfried A. and Meissburger, J{\"u}rgen and Oelert, W. and Seyfart, H. and Styczen, B. and K{\"o}hler, M. and Oelrich, I. and Scheerer, J.}, title = {High resolution spectroscopy of 102Ru(d, p)103Ru and 104Ru(p, d)103Ru reactions}, series = {Nuclear Physics A. Vol. 379, iss. 1}, journal = {Nuclear Physics A. Vol. 379, iss. 1}, issn = {1873-1554 (E-Journal); 0375-9474 (Print)}, pages = {93 -- 109}, year = {1982}, language = {en} } @incollection{BechstedtBergHackeretal.1995, author = {Bechstedt, U. and Berg, Georg P. A. and Hacker, Ulrich and Hardt, Arno and H{\"u}rlimann, Werner and Maier, R. and Martin, Siegfried A. and Meissburger, J{\"u}rgen and R{\"o}mer, Josef G. M. and Possen, P. von and Sagefka, Thomas}, title = {BIG KARL and COSY}, series = {The art and science of magnet design. A Festschrift in honor of Klaus Halbach. Vol. 1}, booktitle = {The art and science of magnet design. A Festschrift in honor of Klaus Halbach. Vol. 1}, publisher = {Lawrence Berkeley Lab., Univ. of California}, address = {Berkeley, CA.}, pages = {19 -- 28}, year = {1995}, language = {en} } @article{MartinHardtMeissburgeretal.1983, author = {Martin, Siegfried A. and Hardt, Arno and Meissburger, J{\"u}rgen and Berg, Georg P. A. and Hacker, Ulrich and H{\"u}rlimann, Werner and R{\"o}mer, Josef G. M. and Sagefka, Thomas and Retz, Adolf and Schult, Otto W. B.}, title = {The QQDDQ magnet spectrometer "BIG KARL"}, series = {Nuclear instruments and methods in physics research. Vol. 214, iss. 2-3}, journal = {Nuclear instruments and methods in physics research. Vol. 214, iss. 2-3}, issn = {0029-554x (E-Journal); 1872-9606 (E-Journal); 0167-5087 (Print)}, pages = {281 -- 303}, year = {1983}, language = {en} } @article{BechstedtHaasHackeretal.1985, author = {Bechstedt, U. and Haas, H. and Hacker, Ulrich and Hardt, Arno and Henn, K. and Martin, Siegfried A. and Wimmer, J.}, title = {Magnets for the German Spallation Source SNQ}, series = {IEEE transactions on nuclear science. Vol. 32, iss. 5}, journal = {IEEE transactions on nuclear science. Vol. 32, iss. 5}, issn = {1558-1578 (E-Journal); 0018-9499 (Print)}, pages = {3631 -- 3633}, year = {1985}, language = {en} } @article{SchultSistemichHardt1995, author = {Schult, Otto W. B. and Sistemich, K. and Hardt, Arno}, title = {Plans for investigations of subthreshold K+ production in p+A collisions / O. W. B. Schult [u.a.]}, series = {Nuclear Physics A. Vol. 583}, journal = {Nuclear Physics A. Vol. 583}, issn = {1873-1554 (E-journal); 0375-9474 (Print)}, pages = {629 -- 632}, year = {1995}, language = {en} } @inproceedings{MartinBergHardtetal.1979, author = {Martin, Siegfried A. and Berg, G. and Hardt, Arno and H{\"u}rlimann, Werner and K{\"o}hler, M. and Meißberger, J. and Sagefka, Thomas and Schult, Otto W. B.}, title = {First experience with the magnet spectrometer 'BIG KARL'}, series = {Use of magnetic spectrometers in nuclear physics : proceedings of the Daresbury study weekend 10 - 11 March 1979}, booktitle = {Use of magnetic spectrometers in nuclear physics : proceedings of the Daresbury study weekend 10 - 11 March 1979}, editor = {Sanderson, N. E.}, publisher = {Daresbury Lab.}, address = {Daresbury}, pages = {38 -- 42}, year = {1979}, language = {en} } @article{Grotendorst2012, author = {Grotendorst, Johannes}, title = {IAS Winter School: Hierarchical Methods for Dynamics in Complex Molecular Systems}, series = {Innovatives Supercomputing in Deutschland : inSiDE}, volume = {10}, journal = {Innovatives Supercomputing in Deutschland : inSiDE}, publisher = {HLRS}, address = {Stuttgart}, pages = {104 -- 1}, year = {2012}, language = {en} } @article{MartinBergHackeretal.1985, author = {Martin, Siegfried A. and Berg, Georg P. A. and Hacker, Ulrich and Hardt, Arno and K{\"o}hler, M. and Meissburger, J{\"u}rgen and Osterfeld, F. and Prasuhn, D. and Riepe, G. and Rogge, M. and Schult, Otto W. B. and Speth, J. and Turek, P. and Gaul, G. and Hagedoorn, H. and Heide, J. A. van der and Hinterberger, F. and Huber, M. and Jahn, R. and Mayer-Kuckuk, T. and Poth, H. and Paetz gen. Schieck, H.}, title = {COSY - a cooler synchrotron and storage ring}, series = {IEEE transactions on nuclear science. Vol. 32, iss. 5}, journal = {IEEE transactions on nuclear science. Vol. 32, iss. 5}, issn = {1558-1578 (E-Journal); 0018-9499 (Print)}, pages = {2694 -- 2696}, year = {1985}, language = {en} } @book{BergGaulHagedoornetal.1984, author = {Berg, Georg P. A. and Gaul, G. and Hagedoorn, H. and Hardt, Arno and Heide, J. A. van der and Hinterberger, F. and Huber, Max and Jahn, R. and Martin, Siegfried A. and Mayer-Kuckuk, T. and Osterfeld, F. and Paetz gen. Schieck, H. and Prasuhn, D. and Riepe, G. and Rogge, M. and Rossen, P. von and Schult, Otto W. B. and Speth, J. and Turek, P.}, title = {Studie zum Bau eines kombinierten K{\"u}hler-Synchrotron-Rings an der KFA J{\"u}lich: COSY-Studie. Spezielle Berichte der Kernforschungsanlage J{\"u}lich. Nr. 0242. J{\"u}l-Spez-242}, publisher = {Kernforschungsanlage}, address = {J{\"u}lich}, pages = {65 S.}, year = {1984}, language = {de} } @article{SchoeningThustSteffenetal.1996, author = {Sch{\"o}ning, Michael Josef and Thust, M. and Steffen, A. and Kordos, P. and L{\"u}th, H. and Kauffmann, F. and Hoffmann, B.}, title = {Halbleiter-Biosensoren f{\"u}r den Penicillin-Nachweis in w{\"a}ßrigen L{\"o}sungen}, series = {Gesellschaft Mess- und Automatisierungstechnik: Sensoren und Messysteme : Tagung Bad Nauheim, 11. bis 13. M{\"a}rz 1996 / VDI/VDE-Gesellschaft Meß- und Automatisierungstechnik.}, journal = {Gesellschaft Mess- und Automatisierungstechnik: Sensoren und Messysteme : Tagung Bad Nauheim, 11. bis 13. M{\"a}rz 1996 / VDI/VDE-Gesellschaft Meß- und Automatisierungstechnik.}, publisher = {VDI-Verl.}, address = {D{\"u}sseldorf}, isbn = {3-18-091255-3}, pages = {143 -- 148}, year = {1996}, language = {de} } @article{SchoeningBrunsHoffmannetal.1993, author = {Sch{\"o}ning, Michael Josef and Bruns, M. and Hoffmann, W. and Hoffmann, B.}, title = {Iodide ion-sensitive field-effect structures}, series = {Sensors and Actuators B. 15 (1993), H. 1-3}, journal = {Sensors and Actuators B. 15 (1993), H. 1-3}, isbn = {0925-4005}, pages = {192 -- 194}, year = {1993}, language = {en} } @article{BehbahaniProbstMaietal.2010, author = {Behbahani, Mehdi and Probst, M. and Mai, A. and Behr, Marek and Tran, L. and Vonderstein, K. and Mottaghy, K.}, title = {Numerical Prediction of Blood Damage in Biomedical Devices}, year = {2010}, language = {en} } @book{HoffmannLindemann1998, author = {Hoffmann, Christoph P. and Lindemann, Markus}, title = {Logistik und Electronic Commerce - LogEC : Arbeitsbericht}, publisher = {mcm Inst.}, address = {St. Gallen}, isbn = {3-906979-00-8}, pages = {XX, 161 S. : graph. Darst.}, year = {1998}, language = {de} } @article{Hillgaertner2010, author = {Hillg{\"a}rtner, Michael}, title = {Normative Regulations}, series = {ECPE Cluster Seminar EMC in Hybrid and Electric Vehicles : 18 May 2010, Fraunhofer Institute Erlangen}, journal = {ECPE Cluster Seminar EMC in Hybrid and Electric Vehicles : 18 May 2010, Fraunhofer Institute Erlangen}, publisher = {European Center for Power Electronics}, address = {N{\"u}rnberg}, year = {2010}, language = {en} } @unpublished{BremmBlaneckBornheimetal.2024, author = {Bremm, Florian and Blaneck, Patrick Gustav and Bornheim, Tobias and Grieger, Niklas and Bialonski, Stephan}, title = {Preprint: Detecting sexism in German online newspaper comments with open-source text embeddings}, series = {arXiv}, journal = {arXiv}, doi = {10.48550/arXiv.2403.08592}, pages = {6 Seiten}, year = {2024}, abstract = {Sexism in online media comments is a pervasive challenge that often manifests subtly, complicating moderation efforts as interpretations of what constitutes sexism can vary among individuals. We study monolingual and multilingual open-source text embeddings to reliably detect sexism and misogyny in Germanlanguage online comments from an Austrian newspaper. We observed classifiers trained on text embeddings to mimic closely the individual judgements of human annotators. Our method showed robust performance in the GermEval 2024 GerMS-Detect Subtask 1 challenge, achieving an average macro F1 score of 0.597 (4th place, as reported on Codabench). It also accurately predicted the distribution of human annotations in GerMS-Detect Subtask 2, with an average Jensen-Shannon distance of 0.301 (2nd place). The computational efficiency of our approach suggests potential for scalable applications across various languages and linguistic contexts.}, language = {en} } @unpublished{BornheimGriegerBlanecketal.2023, author = {Bornheim, Tobias and Grieger, Niklas and Blaneck, Patrick Gustav and Bialonski, Stephan}, title = {Preprint: Speaker attribution in German parliamentary debates with QLoRA-adapted large language models}, series = {arXiv}, journal = {arXiv}, doi = {10.48550/arXiv.2309.09902}, pages = {8 Seiten}, year = {2023}, abstract = {The growing body of political texts opens up new opportunities for rich insights into political dynamics and ideologies but also increases the workload for manual analysis. Automated speaker attribution, which detects who said what to whom in a speech event and is closely related to semantic role labeling, is an important processing step for computational text analysis. We study the potential of the large language model family Llama 2 to automate speaker attribution in German parliamentary debates from 2017-2021. We fine-tune Llama 2 with QLoRA, an efficient training strategy, and observe our approach to achieve competitive performance in the GermEval 2023 Shared Task On Speaker Attribution in German News Articles and Parliamentary Debates. Our results shed light on the capabilities of large language models in automating speaker attribution, revealing a promising avenue for computational analysis of political discourse and the development of semantic role labeling systems.}, language = {en} } @article{HoffmannSchermutzkiWinckelmannSchlieper2010, author = {Hoffmann, Ulrich and Schermutzki, Margret and Winckelmann-Schlieper, Katja}, title = {Kompetenzbasierte Verzahnung von berufspraktischem und wissenschaftlichem Lernen : Der Studiengang Prozesstechnik der FH Aachen}, series = {Berufsbildung in Wissenschaft und Praxis}, volume = {39}, journal = {Berufsbildung in Wissenschaft und Praxis}, number = {2}, publisher = {Bundesinstitut f{\"u}r Berufsbildung (BiBB)}, address = {Bonn}, issn = {0341-4515}, url = {http://nbn-resolving.de/urn:nbn:de:0035-bwp-10232-7}, pages = {32 -- 36}, year = {2010}, abstract = {Durch rapide gesellschaftliche Ver{\"a}nderungen und neue Anforderungen auf dem Arbeitsmarkt gewinnt die akademische berufliche Weiterbildung zunehmend an Bedeutung. Die Nachfrage nach entsprechenden Angeboten ist sowohl seitens der Unternehmen als auch der Arbeitnehmer/-innen hoch. Die Hochschulen sind aufgefordert, darauf zu reagieren und Wege f{\"u}r lebenslanges Lernen aufzuzeigen, indem sie außerhalb der Hochschule erworbene Kenntnisse auf Hochschulabschl{\"u}sse anerkennen und M{\"o}glichkeiten schaffen, diese Kenntnisse mit dem Ziel weiterzuentwickeln, einen akademischen Abschluss zu erreichen. Dieser Beitrag stellt einen Studiengang vor, der es Berufst{\"a}tigen erm{\"o}glicht, durch die Anrechnung beruflich erworbener Kompetenzen bis zu 50 Prozent der zu erbringenden Studienleistung abzugelten.}, language = {de} } @article{Hoffmann2008, author = {Hoffmann, Ulrich}, title = {Neue Wege in die Hochschule - Beispiel des berufsbegleitenden Studienganges Prozesstechnik der FH Aachen und der Rhein-Erft Akademie}, series = {HIS: Forum Hochschule. 2008 (2008), H. F14}, journal = {HIS: Forum Hochschule. 2008 (2008), H. F14}, isbn = {1863-5563}, pages = {130 -- 138}, year = {2008}, language = {de} } @article{FeuerriegelHoffmannWalenziketal.2001, author = {Feuerriegel, Uwe and Hoffmann, Ulrich and Walenzik, C. and K{\"o}gel, J.}, title = {F{\"u}r Scale-up´s und Betriebsmuster, Projekt Trocknungstechnik an der FH Aachen}, series = {CITplus : das Praxismagazin f{\"u}r Verfahrenstechnik und Apparatebau. 4 (2001)}, journal = {CITplus : das Praxismagazin f{\"u}r Verfahrenstechnik und Apparatebau. 4 (2001)}, isbn = {1436-2597}, pages = {24 -- 25}, year = {2001}, language = {de} } @article{KahmannRauschPluemeretal.2022, author = {Kahmann, Stephanie Lucina and Rausch, Valentin and Pl{\"u}mer, Jonathan and M{\"u}ller, Lars-Peter and Pieper, Martin and Wegmann, Kilian}, title = {The automized fracture edge detection and generation of three-dimensional fracture probability heat maps}, series = {Medical Engineering \& Physics}, volume = {2022}, journal = {Medical Engineering \& Physics}, number = {110}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1350-4533}, pages = {7 Seiten}, year = {2022}, abstract = {With proven impact of statistical fracture analysis on fracture classifications, it is desirable to minimize the manual work and to maximize repeatability of this approach. We address this with an algorithm that reduces the manual effort to segmentation, fragment identification and reduction. The fracture edge detection and heat map generation are performed automatically. With the same input, the algorithm always delivers the same output. The tool transforms one intact template consecutively onto each fractured specimen by linear least square optimization, detects the fragment edges in the template and then superimposes them to generate a fracture probability heat map. We hypothesized that the algorithm runs faster than the manual evaluation and with low (< 5 mm) deviation. We tested the hypothesis in 10 fractured proximal humeri and found that it performs with good accuracy (2.5 mm ± 2.4 mm averaged Euclidean distance) and speed (23 times faster). When applied to a distal humerus, a tibia plateau, and a scaphoid fracture, the run times were low (1-2 min), and the detected edges correct by visual judgement. In the geometrically complex acetabulum, at a run time of 78 min some outliers were considered acceptable. An automatically generated fracture probability heat map based on 50 proximal humerus fractures matches the areas of high risk of fracture reported in medical literature. Such automation of the fracture analysis method is advantageous and could be extended to reduce the manual effort even further.}, language = {en} } @article{AbelKahmannMellonetal.2020, author = {Abel, Alexander and Kahmann, Stephanie Lucina and Mellon, Stephen and Staat, Manfred and Jung, Alexander}, title = {An open-source tool for the validation of finite element models using three-dimensional full-field measurements}, series = {Medical Engineering \& Physics}, volume = {77}, journal = {Medical Engineering \& Physics}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1350-4533}, doi = {10.1016/j.medengphy.2019.10.015}, pages = {125 -- 129}, year = {2020}, abstract = {Three-dimensional (3D) full-field measurements provide a comprehensive and accurate validation of finite element (FE) models. For the validation, the result of the model and measurements are compared based on two respective point-sets and this requires the point-sets to be registered in one coordinate system. Point-set registration is a non-convex optimization problem that has widely been solved by the ordinary iterative closest point algorithm. However, this approach necessitates a good initialization without which it easily returns a local optimum, i.e. an erroneous registration. The globally optimal iterative closest point (Go-ICP) algorithm has overcome this drawback and forms the basis for the presented open-source tool that can be used for the validation of FE models using 3D full-field measurements. The capability of the tool is demonstrated using an application example from the field of biomechanics. Methodological problems that arise in real-world data and the respective implemented solution approaches are discussed.}, language = {en} } @article{YangKriechbaumerAlbrachtetal.2014, author = {Yang, Peng-Fei and Kriechbaumer, Andreas and Albracht, Kirsten and Sanno, Maximilian and Ganse, Bergita and Koy, Timmo and Shang, Peng and Br{\"u}ggemann, Gert-Peter and M{\"u}ller, Lars-Peter and Rittweger, J{\"o}rn}, title = {A novel optical approach for assessing in vivo bone segment deformation and its application in muscle-bone relationship studies in humans}, series = {Journal of Orthopaedic Translation}, volume = {2}, journal = {Journal of Orthopaedic Translation}, number = {4}, publisher = {Elsevier}, address = {Singapore}, issn = {2214-0328}, doi = {10.1016/j.jot.2014.07.078}, pages = {238 -- 238}, year = {2014}, language = {en} } @article{MeyerGaalenLeschingeretal.2019, author = {Meyer, Carolin and Gaalen, Kerstin van and Leschinger, Tim and Scheyerer, Max J. and Neiss, Wolfram F. and Staat, Manfred and M{\"u}ller, Lars-Peter and Wegmann, Kilian}, title = {Kyphoplasty of Osteoporotic Fractured Vertebrae: A Finite Element Analysis about Two Types of Cement}, series = {BioMed Research International}, journal = {BioMed Research International}, doi = {10.1155/2019/9232813}, pages = {Article ID 9232813}, year = {2019}, language = {en} } @article{HacklBuessKammerlohretal.2021, author = {Hackl, Michael and Buess, Eduard and Kammerlohr, Sandra and Nacov, Julia and Staat, Manfred and Leschinger, Tim and M{\"u}ller, Lars-Peter and Wegmann, Kilian}, title = {A "comma sign"-directed subscapularis repair in anterosuperior rotator cuff tears yields biomechanical advantages in a cadaveric model}, series = {The american journal of sports medicine}, volume = {49}, journal = {The american journal of sports medicine}, number = {12}, publisher = {Sage}, address = {London}, issn = {1552-3365}, doi = {10.1177/03635465211031506}, pages = {3212 -- 3217}, year = {2021}, abstract = {Background: Additional stabilization of the "comma sign" in anterosuperior rotator cuff repair has been proposed to provide biomechanical benefits regarding stability of the repair. Purpose: This in vitro investigation aimed to investigate the influence of a comma sign-directed reconstruction technique for anterosuperior rotator cuff tears on the primary stability of the subscapularis tendon repair. Study Design: Controlled laboratory study. Methods: A total of 18 fresh-frozen cadaveric shoulders were used in this study. Anterosuperior rotator cuff tears (complete full-thickness tear of the supraspinatus and subscapularis tendons) were created, and supraspinatus repair was performed with a standard suture bridge technique. The subscapularis was repaired with either a (1) single-row or (2) comma sign technique. A high-resolution 3D camera system was used to analyze 3-mm and 5-mm gap formation at the subscapularis tendon-bone interface upon incremental cyclic loading. Moreover, the ultimate failure load of the repair was recorded. A Mann-Whitney test was used to assess significant differences between the 2 groups. Results: The comma sign repair withstood significantly more loading cycles than the single-row repair until 3-mm and 5-mm gap formation occurred (P≤ .047). The ultimate failure load did not reveal any significant differences when the 2 techniques were compared (P = .596). Conclusion: The results of this study show that additional stabilization of the comma sign enhanced the primary stability of subscapularis tendon repair in anterosuperior rotator cuff tears. Although this stabilization did not seem to influence the ultimate failure load, it effectively decreased the micromotion at the tendon-bone interface during cyclic loading. Clinical Relevance: The proposed technique for stabilization of the comma sign has shown superior biomechanical properties in comparison with a single-row repair and might thus improve tendon healing. Further clinical research will be necessary to determine its influence on the functional outcome.}, language = {en} } @article{RauschHarbrechtKahmannetal.2020, author = {Rausch, Valentin and Harbrecht, Andreas and Kahmann, Stephanie Lucina and Fenten, Thomas and Jovanovic, Nebojsa and Hackl, Michael and M{\"u}ller, Lars-Peter and Staat, Manfred and Wegmann, Kilian}, title = {Osteosynthesis of Phalangeal Fractures: Biomechanical Comparison of Kirschner Wires, Plates, and Compression Screws}, series = {The Journal of Hand Surgery}, volume = {45}, journal = {The Journal of Hand Surgery}, number = {10}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0363-5023}, doi = {10.1016/j.jhsa.2020.04.010}, pages = {987.e1 -- 987.e8}, year = {2020}, abstract = {Purpose The aim of this study was to compare several osteosynthesis techniques (intramedullary headless compression screws, T-plates, and Kirschner wires) for distal epiphyseal fractures of proximal phalanges in a human cadaveric model. Methods A total of 90 proximal phalanges from 30 specimens (index, ring, and middle fingers) were used for this study. After stripping off all soft tissue, a transverse distal epiphyseal fracture was simulated at the proximal phalanx. The 30 specimens were randomly assigned to 1 fixation technique (30 per technique), either a 3.0-mm intramedullary headless compression screw, locking plate fixation with a 2.0-mm T-plate, or 2 oblique 1.0-mm Kirschner wires. Displacement analysis (bending, distraction, and torsion) was performed using optical tracking of an applied random speckle pattern after osteosynthesis. Biomechanical testing was performed with increasing cyclic loading and with cyclic load to failure using a biaxial torsion-tension testing machine. Results Cannulated intramedullary compression screws showed significantly less displacement at the fracture site in torsional testing. Furthermore, screws were significantly more stable in bending testing. Kirschner wires were significantly less stable than plating or screw fixation in any cyclic load to failure test setup. Conclusions Intramedullary compression screws are a highly stable alternative in the treatment of transverse distal epiphyseal phalangeal fractures. Kirschner wires seem to be inferior regarding displacement properties and primary stability. Clinical relevance Fracture fixation of phalangeal fractures using plate osteosynthesis may have the advantage of a very rigid reduction, but disadvantages such as stiffness owing to the more invasive surgical approach and soft tissue irritation should be taken into account. Headless compression screws represent a minimally invasive choice for fixation with good biomechanical properties.}, language = {en} } @inproceedings{KahmannUschokWegmannetal.2018, author = {Kahmann, Stephanie Lucina and Uschok, Stephan and Wegmann, Kilian and M{\"u}ller, Lars-Peter and Staat, Manfred}, title = {Biomechanical multibody model with refined kinematics of the elbow}, series = {6th European Conference on Computational Mechanics (ECCM 6), 7th European Conference on Computational Fluid Dynamics (ECFD 7), 11-15 June 2018, Glasgow, UK}, booktitle = {6th European Conference on Computational Mechanics (ECCM 6), 7th European Conference on Computational Fluid Dynamics (ECFD 7), 11-15 June 2018, Glasgow, UK}, pages = {11 Seiten}, year = {2018}, abstract = {The overall objective of this study is to develop a new external fixator, which closely maps the native kinematics of the elbow to decrease the joint force resulting in reduced rehabilitation time and pain. An experimental setup was designed to determine the native kinematics of the elbow during flexion of cadaveric arms. As a preliminary study, data from literature was used to modify a published biomechanical model for the calculation of the joint and muscle forces. They were compared to the original model and the effect of the kinematic refinement was evaluated. Furthermore, the obtained muscle forces were determined in order to apply them in the experimental setup. The joint forces in the modified model differed slightly from the forces in the original model. The muscle force curves changed particularly for small flexion angles but their magnitude for larger angles was consistent.}, language = {en} }