@article{CehreliAkpinarTemizArtmannetal.2015,
  author    = {Cehreli, Ruksan and Akpinar, Hale and Temiz Artmann, Ayseg{\"u}l and Sagol, Ozgul},
  title     = {Effects of Glutamine and Omega-3 Fatty Acids on Erythrocyte Deformability and Oxidative Damage in Rat Model of Enterocolitis},
  series = {Gastroenterology Research},
  volume    = {8},
  journal   = {Gastroenterology Research},
  number    = {5},
  issn      = {1918-2813},
  doi       = {10.14740/gr683w},
  pages     = {265 -- 273},
  year      = {2015},
  language  = {en}
}
@inproceedings{SrivastavaKnolleSchnugetal.2015,
  author    = {Srivastava, Alok and Knolle, F. and Schnug, E. and Scherer, Ulrich W.},
  title     = {Study of Trace Elements in Water Bodies of the Harz Mts. Region, Germany using Total Reflection X Ray Fluorescence (TXRF)},
  series = {DAE-BRNS 12th National Symposium on Nuclear and Radiochemistry NUCAR 2015, Feb. 9-13, Mumbai, India, Mumbai, India; 02/2015},
  booktitle = {DAE-BRNS 12th National Symposium on Nuclear and Radiochemistry NUCAR 2015, Feb. 9-13, Mumbai, India, Mumbai, India; 02/2015},
  pages     = {355 -- 356},
  year      = {2015},
  language  = {de}
}
@incollection{SrivastavaKnolleHoyleretal.2015,
  author    = {Srivastava, Alok and Knolle, Friedhart and Hoyler, Friedrich and Scherer, Ulrich W. and Schnug, Ewald},
  title     = {Uranium Toxicity in the State of Punjab in North-Western India},
  series = {Management of Natural Resources in a Changing Environment},
  booktitle = {Management of Natural Resources in a Changing Environment},
  publisher = {Springer},
  address   = {Cham},
  isbn      = {978-3-319-12559-6},
  doi       = {10.1007/978-3-319-12559-6_21},
  pages     = {271 -- 275},
  year      = {2015},
  abstract  = {Lately there has been an increasing concern about uranium toxicity in some districts of Punjab State located in the North Western part of India after the publication of a report (Blaurock-Busch et al. 2010) which showed that the concentration of uranium in hair and urine of children suffering from physical deformities, neurological and mental disorder from Malwa region (Fig. 1) of Punjab State was manifold higher than the reference ranges. A train which connects the affected region with the nearby city of Bikaner which has a Cancer Hospital has been nicknamed as Cancer Express due to the frenzy generated on account of uranium related toxicity.},
  language  = {en}
}
@book{MuellerRath2015,
  author    = {M{\"u}ller, Bodo and Rath, Walter},
  title     = {Formulierung von Kleb- und Dichtstoffen: das kompetente Lehrbuch f{\"u}r Studium und Praxis},
  edition   = {3., vollst. {\"u}berarb. Aufl.},
  publisher = {Vincentz Network},
  address   = {Hannover},
  isbn      = {978-3-86630-605-9},
  pages     = {375 S. : Ill., graph. Darst},
  year      = {2015},
  language  = {de}
}
@misc{BerndtHoeckerKuropkaetal.1990,
  author    = {Berndt, Heinz and H{\"o}cker, Hartwig and Kuropka, Rolf and Kinkel, Joachim},
  title     = {Silanderivate : Europ{\"a}ische Patenschrift / Offenlegungsschrift},
  publisher = {Europ{\"a}isches Patentamt / Deutsches Patent- und Markenamt},
  address   = {Den Hague / M{\"u}nchen},
  pages     = {10 S. / 13 S. : graph. Darst.},
  year      = {1990},
  language  = {de}
}
@misc{BerndtHoeckerKuropkaetal.1991,
  author    = {Berndt, Heinz and H{\"o}cker, Hartwig and Kuropka, Rolf and Kinkel, Joachim},
  title     = {Silane coated inorganic materials for chromatography : United States Patent},
  publisher = {[The United States Patent and Trademark Office]},
  address   = {[Alexandria, VA u.a.]},
  pages     = {9 S. : graph. Darst.},
  year      = {1991},
  language  = {en}
}
@article{HandtkeSchroeterJuergenetal.2014,
  author    = {Handtke, Stefan and Schroeter, Rebecca and J{\"u}rgen, Britta and Methling, Karen and Schl{\"u}ter, Rabea and Albrecht, Dirk and Hijum, Sacha A. F. T. van and Bongaerts, Johannes and Maurer, Karl-Heinz and Lalk, Michael and Schweder, Thomas and Hecker, Michael and Voigt, Birgit},
  title     = {Bacillus pumilus reveals a remarkably high resistance to hydrogen peroxide provoked oxidative stress},
  series = {PLOS one},
  volume    = {9},
  journal   = {PLOS one},
  number    = {1},
  publisher = {PLOS},
  address   = {San Francisco},
  issn      = {1932-6203},
  doi       = {10.1371/journal.pone.0085625},
  pages     = {e85625},
  year      = {2014},
  abstract  = {Bacillus pumilus is characterized by a higher oxidative stress resistance than other comparable industrially relevant Bacilli such as B. subtilis or B. licheniformis. In this study the response of B. pumilus to oxidative stress was investigated during a treatment with high concentrations of hydrogen peroxide at the proteome, transcriptome and metabolome level. Genes/proteins belonging to regulons, which are known to have important functions in the oxidative stress response of other organisms, were found to be upregulated, such as the Fur, Spx, SOS or CtsR regulon. Strikingly, parts of the fundamental PerR regulon responding to peroxide stress in B. subtilis are not encoded in the B. pumilus genome. Thus, B. pumilus misses the catalase KatA, the DNA-protection protein MrgA or the alkyl hydroperoxide reductase AhpCF. Data of this study suggests that the catalase KatX2 takes over the function of the missing KatA in the oxidative stress response of B. pumilus. The genome-wide expression analysis revealed an induction of bacillithiol (Cys-GlcN-malate, BSH) relevant genes. An analysis of the intracellular metabolites detected high intracellular levels of this protective metabolite, which indicates the importance of bacillithiol in the peroxide stress resistance of B. pumilus.},
  language  = {en}
}
@article{NachtrodtTietschMostaccietal.2014,
  author    = {Nachtrodt, Frederik and Tietsch, Wolfgang and Mostacci, Domiziano and Scherer, Ulrich W.},
  title     = {Set-up and first operation of a plasma oven for treatment of low level radioactive wastes},
  series = {Nuclear technology and radiation protection},
  volume    = {29},
  journal   = {Nuclear technology and radiation protection},
  number    = {Suppl.},
  publisher = {VINČA Institute of Nuclear Sciences},
  address   = {Belgrad},
  issn      = {1451-3994},
  doi       = {10.2298/NTRP140SS47N},
  pages     = {47 -- 51},
  year      = {2014},
  language  = {en}
}
@incollection{FrotscherGossmannRaatschenetal.2015,
  author    = {Frotscher, Ralf and Goßmann, Matthias and Raatschen, Hans-J{\"u}rgen and Temiz Artmann, Ayseg{\"u}l and Staat, Manfred},
  title     = {Simulation of cardiac cell-seeded membranes using the edge-based smoothed FEM},
  series = {Shell and membrane theories in mechanics and biology. (Advanced structured materials ; 45)},
  booktitle = {Shell and membrane theories in mechanics and biology. (Advanced structured materials ; 45)},
  publisher = {Springer},
  address   = {Heidelberg},
  isbn      = {978-3-319-02534-6 ; 978-3-319-02535-3},
  pages     = {187 -- 212},
  year      = {2015},
  abstract  = {We present an electromechanically coupled Finite Element model for cardiac tissue. It bases on the mechanical model for cardiac tissue of Hunter et al. that we couple to the McAllister-Noble-Tsien electrophysiological model of purkinje fibre cells. The corresponding system of ordinary differential equations is implemented on the level of the constitutive equations in a geometrically and physically nonlinear version of the so-called edge-based smoothed FEM for plates. Mechanical material parameters are determined from our own pressure-deflection experimental setup. The main purpose of the model is to further examine the experimental results not only on mechanical but also on electrophysiological level down to ion channel gates. Moreover, we present first drug treatment simulations and validate the model with respect to the experiments.},
  language  = {en}
}
@article{HandtkeVollandMethlingetal.2014,
  author    = {Handtke, Stefan and Volland, Sonja and Methling, Karen and Albrecht, Dirk and Becher, D{\"o}rte and Nehls, Jenny and Bongaerts, Johannes and Maurer, Karl-Heinz and Lalk, Michael and Liesegang, Heiko and Voigt, Birgit and Daniel, Rolf and Hecker, Michael},
  title     = {Cell physiology of the biotechnological relevant bacterium Bacillus pumilus - An omics-based approach},
  series = {Journal of Biotechnology},
  journal   = {Journal of Biotechnology},
  number    = {192(A)},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1873-4863 (E-Journal); 0168-1656 (Print)},
  doi       = {10.1016/j.jbiotec.2014.08.028},
  pages     = {204 -- 214},
  year      = {2014},
  abstract  = {Members of the species Bacillus pumilus get more and more in focus of the biotechnological industry as potential new production strains. Based on exoproteome analysis, B. pumilus strain Jo2, possessing a high secretion capability, was chosen for an omics-based investigation. The proteome and metabolome of B. pumilus cells growing either in minimal or complex medium was analyzed. In total, 1542 proteins were identified in growing B. pumilus cells, among them 1182 cytosolic proteins, 297 membrane and lipoproteins and 63 secreted proteins. This accounts for about 43\% of the 3616 proteins encoded in the B. pumilus Jo2 genome sequence. By using GC-MS, IP-LC/MS and H NMR methods numerous metabolites were analyzed and assigned to reconstructed metabolic pathways. In the genome sequence a functional secretion system including the components of the Sec- and Tat-secretion machinery was found. Analysis of the exoproteome revealed secretion of about 70 proteins with predicted secretion signals. In addition, selected production-relevant genome features such as restriction modification systems and NRPS clusters of B. pumilus Jo2 are discussed.},
  language  = {en}
}
@misc{BesslerEversMaureretal.2009,
  author    = {Bessler, Cornelius and Evers, Stefan and Maurer, Karl-Heinz and Merkel, Marion and Siegert, Petra and Weber, Angrit and Wieland, Susanne},
  title     = {Leistungsverbesserte Proteasen und Wasch- und Reinigungsmittel enthaltend diese Proteasen [Offenlegungsschrift]},
  publisher = {Deutsches Patent- und Markenamt / WIPO},
  address   = {M{\"u}nchen / Genf},
  pages     = {1 -- 41},
  year      = {2009},
  language  = {de}
}
@misc{BesslerMaurerMerkeletal.2009,
  author    = {Bessler, Cornelius and Maurer, Karl-Heinz and Merkel, Marion and Siegert, Petra and Wieland, Susanne},
  title     = {Subtilisin from Bacillus Pumilus and detergent and cleaning agents containing said novel subtilisin [US Patentanmeldung / Internationale Patentanmeldung]},
  publisher = {USPTO; WIPO},
  address   = {Washington; Genf},
  pages     = {1 -- 39},
  year      = {2009},
  language  = {en}
}
@misc{BesslerMaurerMerkeletal.2007,
  author    = {Bessler, Cornelius and Maurer, Karl-Heinz and Merkel, Marion and Siegert, Petra and Wieland, Susanne},
  title     = {Subtilisin aus Bacillus pumilus und Wasch- und Reinigungsmittel enthaltend dieses neue Subtilisin [Offenlegungsschrift]},
  publisher = {Deutsches Patent- und Markenamt / Europ{\"a}isches Patentamt / WIPO / CIPO},
  address   = {M{\"u}nchen / Den Hague / Genf},
  pages     = {1 -- 47},
  year      = {2007},
  language  = {de}
}
@misc{BergBesslerGerlachetal.2009,
  author    = {Berg, Gabriele and Bessler, Cornelius and Gerlach, Jochen and G{\"u}bitz, Georg and Heumann, Sonja and Karl, Wolfgang and Maurer, Karl-Heinz and Remler, Peter and Ribitsch, Doris and Schwab, Helmut and Siegert, Petra and Wieland, Susanne},
  title     = {Mittel enthaltend Proteasen aus Stenotrophomonas maltophilia [Offenlegungsschrift]},
  publisher = {Deutsches Patent- und Markenamt / Europ{\"a}isches Patentamt / USPTO / WIPO},
  address   = {M{\"u}nchen / Den Hague / Washington / Genf},
  pages     = {1 -- 47},
  year      = {2009},
  language  = {de}
}
@misc{SiegertWielandEngelskirchenetal.2008,
  author    = {Siegert, Petra and Wieland, Susanne and Engelskirchen, Julia and Merkel, Marion and Maurer, Karl-Heinz and Bessler, Cornelius},
  title     = {Neue Alkalische Protease aus Bacillus gibsonii und Wasch- und Reinigungsmittel enthaltend diese neue Alkalische Protease [Offenlegungsschrift]},
  publisher = {Deutsches Patentamt / Europ{\"a}isches Patentamt / WIPO},
  address   = {M{\"u}nchen / Den Hague / Genf},
  pages     = {1 -- 51},
  year      = {2008},
  language  = {de}
}
@misc{MerkelWeberSiegertetal.2006,
  author    = {Merkel, Marion and Weber, Angrit and Siegert, Petra and Wieland, Susanne and Maurer, Karl-Heinz and Bessler, Cornelius},
  title     = {Neue Alkalische Protease aus Bacillus gibsonii und Wasch- und Reinigungsmittel enthaltend diese neue Alkalische Protease [Offenlegungsschrift]},
  publisher = {Deutsches Patent- und Markenamt / WIPO},
  address   = {M{\"u}nchen / Genf},
  pages     = {1 -- 46},
  year      = {2006},
  language  = {de}
}
@misc{O'ConnellHovenSiegertetal.2007,
  author    = {O'Connell, Timothy and Hoven, Nina and Siegert, Petra and Maurer, Karl-Heinz},
  title     = {Amadoriasen in Wasch- und Reinigungsmitteln [Offenlegungsschrift]},
  publisher = {Deutsches Patent- und Markenamt / Europ{\"a}isches Patentamt / WIPO},
  address   = {M{\"u}nchen / Den Hague / Genf},
  pages     = {1 -- 45},
  year      = {2007},
  language  = {de}
}
@misc{SchulzezurWiescheOttoKleenetal.2005,
  author    = {Schulze zur Wiesche, Erik and Otto, Ralf and Kleen, Astrid and Hollenberg, Detlef and S{\"a}ttler, Andrea and Siegert, Petra and Boßmann, Britta},
  title     = {Verfahren zur dauerhaften Ausr{\"u}stung keratinischer Fasern mit Pflegewirkstoffen durch Carboxylesterhydrolasen [Offenlegungsschrift]},
  publisher = {Deutsches Patent- und Markenamt / Europ{\"a}isches Patentamt},
  address   = {M{\"u}nchen / Den Hague},
  pages     = {1 -- 13},
  year      = {2005},
  language  = {de}
}
@misc{KluinMaurerBanowskietal.2005,
  author    = {Kluin, Cornelia and Maurer, Karl-Heinz and Banowski, Bernhard and Bessler, Cornelius and Siegert, Petra},
  title     = {Verwendung von Siderophoren gegen Geruchskeime [Offenlegungsschrift]},
  publisher = {Deutsches Patent- und Markenamt},
  address   = {M{\"u}nchen},
  pages     = {1 -- 32},
  year      = {2005},
  language  = {de}
}
@misc{BankowskiHoffmannWadleetal.2003,
  author    = {Bankowski, Bernhard and Hoffmann, Daniele and Wadle, Armin and Siegert, Petra and S{\"a}ttler, Andrea and Gerke, Thomas},
  title     = {Beta-Glucuronidase-Inhibitoren in Deodorantien und Antitranspirantien [Offenlegungsschrift]},
  publisher = {Deutsches Patent- und Markenamt / Europ{\"a}isches Patentamt / WIPO},
  address   = {M{\"u}nchen / Den Hague / Genf},
  pages     = {1 -- 24},
  year      = {2003},
  language  = {de}
}
@misc{SiegertBankowski2003,
  author    = {Siegert, Petra and Bankowski, Bernhard},
  title     = {Verwendung von Steroidsulfatase-Inhibitoren zur Verminderung von Haarausfall ; Kosmetische und pharmazeutische Zusammensetzungen enthaltend Steroidsulfatase-Inhibitoren und deren Verwendung zur Verminderung von Haarausfall [Offenlegungsschrift]},
  publisher = {Deutsches Patent- und Markenamt / Europ{\"a}isches Patentamt},
  address   = {M{\"u}nchen / Den Hague},
  pages     = {1 -- 38},
  year      = {2003},
  language  = {de}
}
@misc{BanowskiWadleSiegert2004,
  author    = {Banowski, Bernhard and Wadle, Armin and Siegert, Petra},
  title     = {Arylsulfatase-Inhibitoren in Deodorantien und Antitranspirantien [Offenlegungsschrift]},
  publisher = {Deutsches Patent- und Markenamt / Europ{\"a}isches Patentamt},
  address   = {M{\"u}nchen / Den Hague},
  pages     = {1 -- 15},
  year      = {2004},
  language  = {de}
}
@misc{BanowskiWadleSiegert2003,
  author    = {Banowski, Bernhard and Wadle, Armin and Siegert, Petra},
  title     = {Arylsulfatase-Inhibitoren in Deodorantien und Antitranspirantien [Offenlegungsschrift]},
  publisher = {Deutsches Patent- und Markenamt},
  address   = {M{\"u}nchen},
  pages     = {1 -- 20},
  year      = {2003},
  language  = {de}
}
@misc{BanowskiHoffmannWadleetal.2002,
  author    = {Banowski, Bernhard and Hoffmann, Daniele and Wadle, Armin and Siegert, Petra and S{\"a}ttler, Andrea and Gerke, Thomas},
  title     = {Arylsulfatase-Inhibitoren in Deodorantien und Antitranspirantien [Offenlegungsschrift]},
  publisher = {Deutsches Patent- und Markenamt / Polish Patent Office / WIPO},
  address   = {M{\"u}nchen / Warsaw / Genf},
  pages     = {1 -- 22},
  year      = {2002},
  language  = {de}
}
@misc{BanowskiWadleSiegert2005,
  author    = {Banowski, Bernhard and Wadle, Armin and Siegert, Petra},
  title     = {Use of hydroxydiphenyl ether derivatives as arylsulfatase-inhibitors in deodorants and antiperspirants [Europ{\"a}ische Patentanmeldung / US Patentanmeldung / Australische Patentanmeldung / Internationale Patentanmeldung]},
  publisher = {Europ{\"a}isches Patentamt / USPTO / IP Australia / WIPO},
  address   = {Den Hague / Washington / Canberra/ Genf},
  pages     = {1 -- 40},
  year      = {2005},
  language  = {de}
}
@misc{SchmitzSpitzMerkeletal.2004,
  author    = {Schmitz, Susanne and Spitz, Astrid and Merkel, Marion and Siegert, Petra},
  title     = {Verfahren zur Bestimmung des enzymatischen Status humaner Haut in vitro [Offenlegungsschrift]},
  publisher = {Deutsches Patent- und Markenamt / Europ{\"a}isches Patentamt / IP Australia / WIPO},
  address   = {M{\"u}nchen / Den Hague / Canberra / Genf},
  pages     = {1 -- 7},
  year      = {2004},
  language  = {de}
}
@misc{BanowskiWadleSiegertetal.2004,
  author    = {Banowski, Bernhard and Wadle, Armin and Siegert, Petra and S{\"a}ttler, Andrea},
  title     = {Lipase-Inhibitoren in Deodorantien und Antitranspirantien [Offenlegungsschrift]},
  publisher = {Deutsches Patent- und Markenamt / Europ{\"a}isches Patentamt},
  address   = {M{\"u}nchen / Den Hague},
  pages     = {1 -- 22},
  year      = {2004},
  language  = {de}
}
@misc{BanowskiWaldmannLaueWadleetal.2004,
  author    = {Banowski, Bernhard and Waldmann-Laue, Marianne and Wadle, Armin and Siegert, Petra and S{\"a}ttler, Andreas},
  title     = {5-Lipoxigenase-Inhibitoren in Deodorantien und Antitranspirantien [Offenlegungsschrift]},
  publisher = {Deutsches Patent- und Markenamt / Europ{\"a}isches Patentamt},
  address   = {M{\"u}nchen / Den Hague},
  pages     = {1 -- 12},
  year      = {2004},
  language  = {de}
}
@article{RatkeMilowLisinskietal.2014,
  author    = {Ratke, Lorenz and Milow, Barbara and Lisinski, Susanne and Hoepfner, Sandra},
  title     = {On an effect of fine ceramic particles on the structure of aerogels},
  series = {Microgravity science and technology},
  volume    = {26},
  journal   = {Microgravity science and technology},
  publisher = {Springer Nature},
  address   = {Heidelberg},
  issn      = {0938-0108 ; 1875-0494},
  doi       = {10.1007/s12217-014-9380-2},
  pages     = {103 -- 110},
  year      = {2014},
  language  = {en}
}
@article{SeiblerKleinriddersKueterLuksetal.2007,
  author    = {Seibler, Jost and Kleinridders, Andre and K{\"u}ter-Luks, Birgit and Niehaves, Sandra and Br{\"u}ning, Jens C. and Schwenk, Frieder},
  title     = {Reversible gene knockdown in mice using a tight, inducible shRNA expression system},
  series = {Nucleic Acids Research},
  volume    = {35},
  journal   = {Nucleic Acids Research},
  number    = {7},
  issn      = {1362-4962},
  doi       = {10.1093/nar/gkm122},
  pages     = {e54},
  year      = {2007},
  language  = {en}
}
@article{PlumMaHampeletal.2006,
  author    = {Plum, Leona and Ma, Xiaosong and Hampel, Brigitte and Balthasar, Nina and Coppari, Roberto and M{\"u}nzberg, Heike and Shanabrough, Marya and Burdakov, Denis and Rother, Eva and Janoschek, Ruth and Alber, Jens and Belgardt, Bengt F. and Koch, Linda and Seibler, Jost and Schenk, Frieder and Fekete, Csaba and Suzuki, Akira and Mak, Tak W. and Krone, Wilhelm and Horvath, Tamas L. and Ashcroft, Frances M. and Br{\"u}ning, Jens C.},
  title     = {Enhanced PIP3 signaling in POMC neurons causes KATP channel activation and leads to diet-sensitive obesity},
  series = {The Journal of Clinical Investigation (JCI)},
  volume    = {116},
  journal   = {The Journal of Clinical Investigation (JCI)},
  number    = {7},
  issn      = {1558-8238},
  doi       = {10.1172/JCI27123},
  pages     = {1886 -- 1901},
  year      = {2006},
  language  = {en}
}
@article{SeiblerKueterLuksKernetal.2005,
  author    = {Seibler, Jost and K{\"u}ter-Luks, Birgit and Kern, Heidrun and Streu, Sandra and Plum, Leona and Maurer, Jan and K{\"u}hn, Ralf and Br{\"u}ning, Jens C. and Schwenk, Frieder},
  title     = {Single copy shRNA configuration for ubiquitous gene knockdown in mice},
  series = {Nucleic Acids Research},
  volume    = {33},
  journal   = {Nucleic Acids Research},
  number    = {7},
  issn      = {1362-4962},
  doi       = {10.1093/nar/gni065},
  pages     = {e67},
  year      = {2005},
  language  = {en}
}
@article{SeiblerZevnikKueterLuksetal.2003,
  author    = {Seibler, Jost and Zevnik, Branko and K{\"u}ter-Luks, Birgit and Andreas, Susanne and Kern, Heidrun and Hennek, Thomas and Rode, Anja and Heimann, Cornelia and Faust, Nicole and Kauselmann, Gunther and Schoor, Michael and Jaenisch, Rudolf and Rajewsky, Klaus and K{\"u}hn, Ralf and Schwenk, Frieder},
  title     = {Rapid generation of inducible mouse mutants},
  series = {Nucleic Acids Research},
  volume    = {33},
  journal   = {Nucleic Acids Research},
  number    = {4},
  issn      = {1362-4962},
  doi       = {10.1093/nar/gng012},
  pages     = {e12},
  year      = {2003},
  language  = {en}
}
@article{GoetzeBaerWinkelmannetal.2005,
  author    = {Goetze, Sandra and Baer, Alexandra and Winkelmann, Silke and Nehlsen, Kristina and Seibler, Jost and Maass, Karin and Bode, J{\"u}rgen},
  title     = {Performance of genomic bordering elements at predefined genomic loci},
  series = {Molecular and Cellular Biology},
  volume    = {25},
  journal   = {Molecular and Cellular Biology},
  number    = {6},
  issn      = {1098-5549},
  doi       = {10.1128/MCB.25.6.2260-2272.2005},
  pages     = {2260 -- 2272},
  year      = {2005},
  language  = {en}
}
@article{TakenagaSchneiderErbayetal.2015,
  author    = {Takenaga, Shoko and Schneider, Benno and Erbay, E. and Biselli, Manfred and Schnitzler, Thomas and Sch{\"o}ning, Michael Josef and Wagner, Torsten},
  title     = {Fabrication of biocompatible lab-on-chip devices for biomedical applications by means of a 3D-printing process},
  series = {Physica status solidi (a)},
  volume    = {212},
  journal   = {Physica status solidi (a)},
  number    = {6},
  publisher = {Wiley},
  address   = {Weinheim},
  issn      = {1862-6319},
  doi       = {10.1002/pssa.201532053},
  pages     = {1347 -- 1352},
  year      = {2015},
  abstract  = {A new microfluidic assembly method for semiconductor-based biosensors using 3D-printing technologies was proposed for a rapid and cost-efficient design of new sensor systems. The microfluidic unit is designed and printed by a 3D-printer in just a few hours and assembled on a light-addressable potentiometric sensor (LAPS) chip using a photo resin. The cell growth curves obtained from culturing cells within microfluidics-based LAPS systems were compared with cell growth curves in cell culture flasks to examine biocompatibility of the 3D-printed chips. Furthermore, an optimal cell culturing within microfluidics-based LAPS chips was achieved by adjusting the fetal calf serum concentrations of the cell culture medium, an important factor for the cell proliferation.},
  language  = {en}
}
@article{InagakiSleddensLinkelsWassenaaretal.2011,
  author    = {Inagaki, Akiko and Sleddens-Linkels, Esther and Wassenaar, Evelyne and Ooms, Marja and Cappellen, Wiggert A. van and Hoeijmakers, Jan H. J. and Seibler, Jost and Vogt, Thomas F. and Shin, Myung K. and Grootegoed, J. Anton and Baarends, Willy M.},
  title     = {Meiotic functions of RAD18},
  series = {Journal of Cell Science},
  volume    = {124},
  journal   = {Journal of Cell Science},
  number    = {16},
  publisher = {Company of Biologists Limited},
  address   = {Cambridge},
  issn      = {1477-9137},
  doi       = {10.1242/jcs.081968},
  pages     = {2837 -- 2850},
  year      = {2011},
  language  = {en}
}
@article{RaabKappelKraemeretal.2011,
  author    = {Raab, Monika and Kappel, Sven and Kr{\"a}mer, Andrea and Sanhaji, Mourad and Matthess, Yves and Kurunci-Csacsko, Elisabeth and Calzada-Wack, Julia and Rathkolb, Birgit and Rosman, Jan and Adler, Thure and Busch, Dirk H. and Esposito, Irene and Fuchs, Helmut and Gailus-Durner, Val{\´e}rie and Klingenspor, Martin and Wolf, Eckhard and S{\"a}nger, Nicole and Prinz, Florian and Hrabe de Angelis, Martin and Seibler, Jost and Yuan, Juping and Bergmann, Martin and Knecht, Rainald and Kreft, Bertolt and Strebhardt, Klaus},
  title     = {Toxicity modelling of Plk1-targeted therapies in genetically engineered mice and cultured primary mammalian cells},
  series = {Nature Communications},
  volume    = {2},
  journal   = {Nature Communications},
  number    = {395},
  publisher = {Nature},
  address   = {London},
  issn      = {2041-1723},
  doi       = {10.1038/ncomms1395},
  pages     = {1 -- 11},
  year      = {2011},
  language  = {en}
}
@article{HasegawaKapelyukhTaharaetal.2011,
  author    = {Hasegawa, Maki and Kapelyukh, Yury and Tahara, Harunobu and Seibler, Jost and Rode, Anja and Krueger, Sylvia and Lee, Dongtao N. and Wolf, C. Roland and Scheer, Nico},
  title     = {Quantitative prediction of human pregnane X receptor and cytochrome P450 3A4 mediated drug-drug interaction in a novel multiple humanized mouse line},
  series = {Molecular Pharmacology},
  volume    = {80},
  journal   = {Molecular Pharmacology},
  number    = {33},
  publisher = {ASPET},
  address   = {Bethesda, Md.},
  issn      = {1521-0111},
  doi       = {10.1124/mol.111.071845},
  pages     = {518 -- 528},
  year      = {2011},
  language  = {en}
}
@article{JordanKruegerWillmesetal.2011,
  author    = {Jordan, Sabine D. and Kr{\"u}ger, Markus and Willmes, Diana M. and Redemann, Nora and Wunderlich, F. Thomas and Br{\"o}nneke, Hella S. and Merkwirth, Carsten and Kashkar, Hamid and Olkkonen, Vesa M. and B{\"o}ttger, Thomas and Braun, Thomas and Seibler, Jost and Br{\"u}ning, Jens C.},
  title     = {Obesity-induced overexpression of miRNA-143 inhibits insulin-stimulated AKT activation and impairs glucose metabolism},
  series = {Nature Cell Biology},
  volume    = {13},
  journal   = {Nature Cell Biology},
  number    = {4},
  publisher = {Nature},
  address   = {New York},
  issn      = {1465-7392},
  doi       = {10.1038/ncb2211},
  pages     = {434 -- 446},
  year      = {2011},
  abstract  = {The contribution of altered post-transcriptional gene silencing to the development of insulin resistance and type 2 diabetes mellitus so far remains elusive. Here, we demonstrate that expression of microRNA (miR)-143 and 145 is upregulated in the liver of genetic and dietary mouse models of obesity. Induced transgenic overexpression of miR-143, but not miR-145, impairs insulin-stimulated AKT activation and glucose homeostasis. Conversely, mice deficient for the miR-143-145 cluster are protected from the development of obesity-associated insulin resistance. Quantitative-mass-spectrometry-based analysis of hepatic protein expression in miR-143-overexpressing mice revealed miR-143-dependent downregulation of oxysterol-binding-protein-related protein (ORP) 8. Reduced ORP8 expression in cultured liver cells impairs the ability of insulin to induce AKT activation, revealing an ORP8-dependent mechanism of AKT regulation. Our experiments provide direct evidence that dysregulated post-transcriptional gene silencing contributes to the development of obesity-induced insulin resistance, and characterize the miR-143-ORP8 pathway as a potential target for the treatment of obesity-associated diabetes.},
  language  = {en}
}
@incollection{SeiblerSchwenk2010,
  author    = {Seibler, Jost and Schwenk, Frieder},
  title     = {Transgenic RNAi Applications in the Mouse},
  series = {Methods in Enzymology : Guide to Techniques in Mouse Development, Part B: Mouse Molecular Genetics. 2nd Edition},
  booktitle = {Methods in Enzymology : Guide to Techniques in Mouse Development, Part B: Mouse Molecular Genetics. 2nd Edition},
  publisher = {Elsevier},
  address   = {Amsterdam},
  isbn      = {978-0-12-384880-2},
  pages     = {367 -- 386},
  year      = {2010},
  language  = {en}
}
@article{GlaserLubitzLovelandetal.2009,
  author    = {Glaser, Stefan and Lubitz, Sandra and Loveland, Kate L. and Ohbo, Kazu and Robb, Lorraine and Schwenk, Frieder and Seibler, Jost and Roellig, Daniela and Kranz, Andrea and Anastassiadis, Konstantinos and Stewart, A. Francis},
  title     = {The histone 3 lysine 4 methyltransferase, Mll2, is only required briefly in development and spermatogenesis},
  series = {Epigenetics \& Chromatin},
  volume    = {2},
  journal   = {Epigenetics \& Chromatin},
  number    = {5},
  issn      = {1756-8935},
  doi       = {10.1186/1756-8935-2-5},
  pages     = {1 -- 16},
  year      = {2009},
  language  = {en}
}
@article{KotnikPopovaTodirasetal.2009,
  author    = {Kotnik, Katarina and Popova, Elena and Todiras, Mihail and Mori, Marcelo A. and Alenina, Natalia and Seibler, Jost and Bader, Michael},
  title     = {Inducible transgenic rat model for diabetes mellitus based on shRNA-mediated gene knockdown},
  series = {Plos One},
  volume    = {4},
  journal   = {Plos One},
  number    = {4},
  publisher = {Plos},
  address   = {San Francisco, California, US},
  doi       = {10.1371/journal.pone.0005124},
  pages     = {e5124},
  year      = {2009},
  language  = {en}
}
@article{HeroldBrandtSeibleretal.2008,
  author    = {Herold, Marco J. and Brandt, Jens van den and Seibler, Jost and Reichardt, Holger M.},
  title     = {Inducible and reversible gene silencing by stable integration of an shRNA-encoding lentivirus in transgenic rats},
  series = {Proceedings of the National Academy of Sciences of the United States of America},
  volume    = {105},
  journal   = {Proceedings of the National Academy of Sciences of the United States of America},
  number    = {47},
  issn      = {1091-6490},
  doi       = {10.1073/pnas.0806213105},
  pages     = {18507 -- 18512},
  year      = {2008},
  language  = {en}
}
@article{KochWunderlichSeibleretal.2008,
  author    = {Koch, Linda and Wunderlich, F. Thomas and Seibler, Jost and K{\"o}nner, A. Christine and Hampel, Brigitte and Irlenbusch, Sigrid and Brabant, Georg and Kahn, C. Ronald and Schwenk, Frieder and Br{\"u}ning, Jens C.},
  title     = {Central insulin action regulates peripheral glucose and fat metabolism in mice},
  series = {The Journal of Clinical Investigation (JCI)},
  volume    = {118},
  journal   = {The Journal of Clinical Investigation (JCI)},
  number    = {6},
  issn      = {1558-8238},
  doi       = {10.1172/JCI31073},
  pages     = {2132 -- 2147},
  year      = {2008},
  language  = {en}
}
@article{ChristophBahrenbergVryetal.2008,
  author    = {Christoph, Thomas and Bahrenberg, Gregor and Vry, Jean de and Englberger, Werner and Erdmann, Volker A. and Frech, Moritz and K{\"o}gel, Babette and R{\"o}hl, Thomas and Schiene, Klaus and Schr{\"o}der, Wolfgang and Seibler, Jost and Kurreck, Jens},
  title     = {Investigation of TRPV1 loss-of-function phenotypes in transgenic shRNA expressing and knockout mice},
  series = {Molecular and Cellular Neuroscience},
  volume    = {37},
  journal   = {Molecular and Cellular Neuroscience},
  number    = {3},
  issn      = {1044-7431},
  doi       = {10.1016/j.mcn.2007.12.006},
  pages     = {579 -- 589},
  year      = {2008},
  language  = {en}
}
@article{CesariRennekampffVinterstenetal.2004,
  author    = {Cesari, Francesca and Rennekampff, Verena and Vintersten, Kristina and Vuong, Lam Giang and Seibler, Jost and Bode, J{\"u}rgen and Wiebel, Franziska F. and Nordheim, Alfred},
  title     = {Elk-1 knock-out mice engineered by Flp recombinase-mediated cassette exchange},
  series = {Genesis : The Journal of Genetics and Development},
  volume    = {38},
  journal   = {Genesis : The Journal of Genetics and Development},
  number    = {2},
  issn      = {1526-968X},
  doi       = {10.1002/gene.20003},
  pages     = {87 -- 92},
  year      = {2004},
  language  = {en}
}
@article{BodeSchlakeIberetal.2000,
  author    = {Bode, J{\"u}rgen and Schlake, Thomas and Iber, Michaela and Sch{\"u}beler, Dirk and Seibler, Jost and Snezhkov, Evgeney and Nikolaev, Lev},
  title     = {The transgeneticist's toolbox: novel methods for the targeted modification of eukaryotic genomes},
  series = {Biological Chemistry},
  volume    = {381},
  journal   = {Biological Chemistry},
  number    = {9-10},
  issn      = {1431-6730},
  doi       = {10.1515/BC.2000.103},
  pages     = {801 -- 813},
  year      = {2000},
  language  = {en}
}
@article{FengSeiblerAlamietal.1999,
  author    = {Feng, Yong-Qing and Seibler, Jost and Alami, Raouf and Eisen, Andrew and Westerman, Karen A. and Leboulch, Philippe and Fiering, Steven and Bouhassira, Eric E.},
  title     = {Site-specific chromosomal integration in mammalian cells: highly efficient CRE recombinase-mediated cassette exchange},
  series = {Journal of Molecular Biology},
  volume    = {292},
  journal   = {Journal of Molecular Biology},
  number    = {4},
  issn      = {0022-2836},
  doi       = {10.1006/jmbi.1999.3113},
  pages     = {779 -- 785},
  year      = {1999},
  language  = {en}
}
@article{SeiblerSchuebelerFieringetal.1998,
  author    = {Seibler, Jost and Sch{\"u}beler, Dirk and Fiering, Steven and Groudine, Mark and Bode, J{\"u}rgen},
  title     = {DNA cassette exchange in ES cells mediated by Flp recombinase: an efficient strategy for repeated modification of tagged loci by marker-free constructs},
  series = {Biochemistry},
  volume    = {37},
  journal   = {Biochemistry},
  number    = {18},
  issn      = {1520-4995},
  doi       = {10.1021/bi980288t},
  pages     = {6229 -- 6234},
  year      = {1998},
  language  = {en}
}
@article{SeiblerBode1997,
  author    = {Seibler, Jost and Bode, J{\"u}rgen},
  title     = {Double-reciprocal crossover mediated by FLP-recombinase: a concept and an assay},
  series = {Biochemistry},
  volume    = {36},
  journal   = {Biochemistry},
  number    = {7},
  issn      = {1520-4995},
  pages     = {1740 -- 1747},
  year      = {1997},
  language  = {en}
}