@inproceedings{DuongNguyenStaat2015,
  author    = {Duong, Minh Tuan and Nguyen, N. H. and Staat, Manfred},
  title     = {Modeling and simulation of a growing mass by the Smoothed Finite Element Method (SFEM)},
  series = {Conference proceedings of the YIC GACM 2015 : 3rd ECCOMAS Young Investigators Conference and 6th GACM Colloquium on Computational Mechanics , Aachen, Germany, 20.07.2015 - 23.07.2015 / ed.: Stefanie Elgeti ; Jaan-Willem Simon},
  booktitle = {Conference proceedings of the YIC GACM 2015 : 3rd ECCOMAS Young Investigators Conference and 6th GACM Colloquium on Computational Mechanics , Aachen, Germany, 20.07.2015 - 23.07.2015 / ed.: Stefanie Elgeti ; Jaan-Willem Simon},
  publisher = {RWTH Aachen University},
  address   = {Aachen},
  organization    = {ECCOMAS Young Investigators Conference <3, 2015, Aachen>},
  pages     = {1 -- 4},
  year      = {2015},
  language  = {en}
}
@article{KurulganDemirciDemirciLinderetal.2012,
  author    = {Kurulgan Demirci, Eylem and Demirci, Taylan and Linder, Peter and Trzewik, J{\"u}rgen and Gierkowski, Jessica Ricarda and Gossmann, Matthias and Kayser, Peter and Porst, Dariusz and Digel, Ilya and Artmann, Gerhard and Temiz Artmann, Ayseg{\"u}l},
  title     = {rhAPC reduces the endothelial cell permeability via a decrease of contractile tensions induced by endothelial cells},
  series = {Journal of Bioscience and Bioengineering},
  volume    = {113},
  journal   = {Journal of Bioscience and Bioengineering},
  number    = {2},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1347-4421},
  doi       = {10.1016/j.jbiosc.2012.03.019},
  pages     = {212 -- 219},
  year      = {2012},
  abstract  = {All cells generate contractile tension. This strain is crucial for mechanically controlling the cell shape, function and survival. In this study, the CellDrum technology quantifying cell's (the cellular) mechanical tension on a pico-scale was used to investigate the effect of lipopolysaccharide (LPS) on human aortic endothelial cell (HAoEC) tension. The LPS effect during gram-negative sepsis on endothelial cells is cell contraction causing endothelium permeability increase. The aim was to finding out whether recombinant activated protein C (rhAPC) would reverse the endothelial cell response in an in-vitro sepsis model. In this study, the established in-vitro sepsis model was confirmed by interleukin 6 (IL-6) levels at the proteomic and genomic levels by ELISA, real time-PCR and reactive oxygen species (ROS) activation by florescence staining. The thrombin cellular contraction effect on endothelial cells was used as a positive control when the CellDrum technology was applied. Additionally, the Ras homolog gene family, member A (RhoA) mRNA expression level was checked by real time-PCR to support contractile tension results. According to contractile tension results, the mechanical predominance of actin stress fibers was a reason of the increased endothelial contractile tension leading to enhanced endothelium contractility and thus permeability enhancement. The originality of this data supports firstly the basic measurement principles of the CellDrum technology and secondly that rhAPC has a beneficial effect on sepsis influenced cellular tension. The technology presented here is promising for future high-throughput cellular tension analysis that will help identify pathological contractile tension responses of cells and prove further cell in-vitro models.},
  language  = {en}
}
@article{RingersBialonskiEgeetal.2023,
  author    = {Ringers, Christa and Bialonski, Stephan and Ege, Mert and Solovev, Anton and Hansen, Jan Niklas and Jeong, Inyoung and Friedrich, Benjamin M. and Jurisch-Yaksi, Nathalie},
  title     = {Novel analytical tools reveal that local synchronization of cilia coincides with tissue-scale metachronal waves in zebrafish multiciliated epithelia},
  series = {eLife},
  volume    = {12},
  journal   = {eLife},
  publisher = {eLife Sciences Publications},
  issn      = {2050-084X},
  doi       = {10.7554/eLife.77701},
  pages     = {27 Seiten},
  year      = {2023},
  abstract  = {Motile cilia are hair-like cell extensions that beat periodically to generate fluid flow along various epithelial tissues within the body. In dense multiciliated carpets, cilia were shown to exhibit a remarkable coordination of their beat in the form of traveling metachronal waves, a phenomenon which supposedly enhances fluid transport. Yet, how cilia coordinate their regular beat in multiciliated epithelia to move fluids remains insufficiently understood, particularly due to lack of rigorous quantification. We combine experiments, novel analysis tools, and theory to address this knowledge gap. To investigate collective dynamics of cilia, we studied zebrafish multiciliated epithelia in the nose and the brain. We focused mainly on the zebrafish nose, due to its conserved properties with other ciliated tissues and its superior accessibility for non-invasive imaging. We revealed that cilia are synchronized only locally and that the size of local synchronization domains increases with the viscosity of the surrounding medium. Even though synchronization is local only, we observed global patterns of traveling metachronal waves across the zebrafish multiciliated epithelium. Intriguingly, these global wave direction patterns are conserved across individual fish, but different for left and right noses, unveiling a chiral asymmetry of metachronal coordination. To understand the implications of synchronization for fluid pumping, we used a computational model of a regular array of cilia. We found that local metachronal synchronization prevents steric collisions, i.e., cilia colliding with each other, and improves fluid pumping in dense cilia carpets, but hardly affects the direction of fluid flow. In conclusion, we show that local synchronization together with tissue-scale cilia alignment coincide and generate metachronal wave patterns in multiciliated epithelia, which enhance their physiological function of fluid pumping.},
  language  = {en}
}
@article{DemirciTrzewikLinderetal.2004,
  author    = {Demirci, T. and Trzewik, J. and Linder, Peter and Digel, Ilya and Artmann, Gerhard and Temiz Artmann, Ayseg{\"u}l},
  title     = {Mechanical Stimulation of 3T3 Fibroblasts Activates Genes: ITGB5 and p53 Responses as Quantified on the mRNA Level},
  series = {Biomedizinische Technik . 49 (2004), H. Erg.-Bd. 2},
  journal   = {Biomedizinische Technik . 49 (2004), H. Erg.-Bd. 2},
  isbn      = {0932-4666},
  pages     = {1030 -- 1031},
  year      = {2004},
  language  = {en}
}
@article{AsanteAsamaniKleefeldWade2020,
  author    = {Asante-Asamani, E.O. and Kleefeld, Andreas and Wade, B.A.},
  title     = {A second-order exponential time differencing scheme for non-linear reaction-diffusion systems with dimensional splitting},
  series = {Journal of Computational Physics},
  volume    = {415},
  journal   = {Journal of Computational Physics},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0021-9991},
  doi       = {10.1016/j.jcp.2020.109490},
  year      = {2020},
  abstract  = {A second-order L-stable exponential time-differencing (ETD) method is developed by combining an ETD scheme with approximating the matrix exponentials by rational functions having real distinct poles (RDP), together with a dimensional splitting integrating factor technique. A variety of non-linear reaction-diffusion equations in two and three dimensions with either Dirichlet, Neumann, or periodic boundary conditions are solved with this scheme and shown to outperform a variety of other second-order implicit-explicit schemes. An additional performance boost is gained through further use of basic parallelization techniques.},
  language  = {en}
}
@article{MuschallikKippReckeretal.2020,
  author    = {Muschallik, Lukas and Kipp, Carina Ronja and Recker, Inga and Bongaerts, Johannes and Pohl, Martina and Gelissen, Melanie and Sch{\"o}ning, Michael Josef and Selmer, Thorsten and Siegert, Petra},
  title     = {Synthesis of α-hydroxy ketones and vicinal diols with the Bacillus licheniformis DSM 13T butane-2, 3-diol dehydrogenase},
  series = {Journal of Biotechnology},
  volume    = {202},
  journal   = {Journal of Biotechnology},
  number    = {Vol. 324},
  publisher = {Elsevier},
  address   = {Amsterdam},
  isbn      = {2590-1559},
  doi       = {10.1016/j.jbiotec.2020.09.016},
  pages     = {61 -- 70},
  year      = {2020},
  abstract  = {The enantioselective synthesis of α-hydroxy ketones and vicinal diols is an intriguing field because of the broad applicability of these molecules. Although, butandiol dehydrogenases are known to play a key role in the production of 2,3-butandiol, their potential as biocatalysts is still not well studied. Here, we investigate the biocatalytic properties of the meso-butanediol dehydrogenase from Bacillus licheniformis DSM 13T (BlBDH). The encoding gene was cloned with an N-terminal StrepII-tag and recombinantly overexpressed in E. coli. BlBDH is highly active towards several non-physiological diketones and α-hydroxyketones with varying aliphatic chain lengths or even containing phenyl moieties. By adjusting the reaction parameters in biotransformations the formation of either the α-hydroxyketone intermediate or the diol can be controlled.},
  language  = {en}
}
@article{HunkerGossmannRamanetal.2021,
  author    = {Hunker, Jan L. and Gossmann, Matthias and Raman, Aravind Hariharan and Linder, Peter},
  title     = {Artificial neural networks in cardiac safety assessment: Classification of chemotherapeutic compound effects on hiPSC-derived cardiomyocyte contractility},
  series = {Journal of Pharmacological and Toxicological Methods},
  volume    = {111},
  journal   = {Journal of Pharmacological and Toxicological Methods},
  number    = {Article number 107044},
  publisher = {Elsevier},
  address   = {New York},
  issn      = {1056-8719},
  doi       = {10.1016/j.vascn.2021.107044},
  year      = {2021},
  language  = {en}
}
@book{ArtmannTemizArtmannZhubanovaetal.2018,
  author    = {Artmann, Gerhard and Temiz Artmann, Ayseg{\"u}l and Zhubanova, Azhar A. and Digel, Ilya},
  title     = {Biological, physical and technical basics of cell engineering},
  editor    = {Artmann, Gerhard and Temiz Artmann, Ayseg{\"u}l and Zhubanova, Azhar A. and Digel, Ilya},
  publisher = {Springer},
  address   = {Singapore},
  isbn      = {978-981-10-7903-0},
  pages     = {xxiv, 481 Seiten ; Illustrationen, Diagramme},
  year      = {2018},
  language  = {en}
}
@article{StaatSchwartzLangetal.2003,
  author    = {Staat, Manfred and Schwartz, M. and Lang, H. and Wirtz, K. and Heitzer, M.},
  title     = {Design by Analysis of Pressure Components by non-linear Optimization},
  series = {The 10th International Conference on Pressure Vessel Technology, July 7-10, 2003, Vienna, Austria, Proceedings ICPVT-10 / Zeman, J. L. [ed]},
  journal   = {The 10th International Conference on Pressure Vessel Technology, July 7-10, 2003, Vienna, Austria, Proceedings ICPVT-10 / Zeman, J. L. [ed]},
  publisher = {{\"O}GS, {\"O}sterreichische Gesellschaft f{\"u}r Schweißtechnik},
  address   = {Wien},
  isbn      = {3950152814},
  pages     = {59 -- 65},
  year      = {2003},
  language  = {en}
}
@article{StaatHeitzer2002,
  author    = {Staat, Manfred and Heitzer, M.},
  title     = {Limit and Shakedown Analysis with Uncertain Data},
  series = {Stochastic optimization techniques : numerical methods and technical applications / Marti, K. [ed]},
  journal   = {Stochastic optimization techniques : numerical methods and technical applications / Marti, K. [ed]},
  publisher = {Springer},
  address   = {Heidelberg},
  isbn      = {3-540-42889-5},
  pages     = {241 -- 254},
  year      = {2002},
  language  = {en}
}
@article{StadlerZerlinDigeletal.2008,
  author    = {Stadler, Andreas M. and Zerlin, Kay and Digel, Ilya and B{\"u}ldt, Georg and Zaccai, Guiseppe and Artmann, Gerhard},
  title     = {Dynamics and interactions of hemoglobin in red blood cells},
  series = {Tissue Engineering Part A. 14 (2008), H. 5},
  journal   = {Tissue Engineering Part A. 14 (2008), H. 5},
  isbn      = {1937-3341},
  pages     = {724 -- 724},
  year      = {2008},
  language  = {en}
}
@article{AkimbekovDigelTastambeketal.2013,
  author    = {Akimbekov, Nuraly S. and Digel, Ilya and Tastambek, K. T. and Zhubanova, A. A.},
  title     = {Biocompatibility of carbonized rice husk with a rat heart cells line H9c2},
  series = {Experimental Biology},
  volume    = {59},
  journal   = {Experimental Biology},
  number    = {3/1},
  issn      = {1563-0218},
  pages     = {23 -- 25},
  year      = {2013},
  language  = {en}
}
@article{BhattaraiStaat2019,
  author    = {Bhattarai, Aroj and Staat, Manfred},
  title     = {A computational study of organ relocation after laparoscopic pectopexy to repair posthysterectomy vaginal vault prolapse},
  series = {Computer Methods in Biomechanics and Biomedical Engineering: Imaging \& Visualization},
  journal   = {Computer Methods in Biomechanics and Biomedical Engineering: Imaging \& Visualization},
  publisher = {Taylor \& Francis},
  address   = {London},
  issn      = {2168-1171},
  doi       = {10.1080/21681163.2019.1670095},
  year      = {2019},
  language  = {en}
}
@article{FrotscherStaat2014,
  author    = {Frotscher, Ralf and Staat, Manfred},
  title     = {Stresses produced by different textile mesh implants in a tissue equivalent},
  series = {BioNanoMaterials},
  volume    = {15},
  journal   = {BioNanoMaterials},
  number    = {1-2},
  publisher = {De Gruyter},
  address   = {Berlin},
  issn      = {2191-4672 (E-Journal); 2193-066X (E-Journal); 0011-8656 (Print); 1616-0177 (Print); 2193-0651 (Print)},
  doi       = {10.1515/bnm-2014-0003},
  pages     = {25 -- 30},
  year      = {2014},
  abstract  = {Two single-incision mini-slings used for treating urinary incontinence in women are compared with respect to the stresses they produce in their surrounding tissue. In an earlier paper we experimentally observed that these implants produce considerably different stress distributions in a muscle tissue equivalent. Here we perform 2D finite element analyses to compare the shear stresses and normal stresses in the tissue equivalent for the two meshes and to investigate their failure behavior. The results clearly show that the Gynecare TVT fails for increasing loads in a zipper-like manner because it gradually debonds from the surrounding tissue. Contrary to that, the tissue at the ends of the DynaMesh-SIS direct may rupture but only at higher loads. The simulation results are in good agreement with the experimental observations thus the computational model helps to interpret the experimental results and provides a tool for qualitative evaluation of mesh implants.},
  language  = {en}
}
@article{VuStaatTran2007,
  author    = {Vu, Duc Khoi and Staat, Manfred and Tran, Ich Thinh},
  title     = {Analysis of pressure equipment by application of the primal-dual theory of shakedown},
  series = {Communications in Numerical Methods in Engineering. 23 (2007), H. 3},
  journal   = {Communications in Numerical Methods in Engineering. 23 (2007), H. 3},
  isbn      = {1069-8299},
  pages     = {213 -- 225},
  year      = {2007},
  language  = {en}
}
@article{StaatVu2006,
  author    = {Staat, Manfred and Vu, Khoi Duc},
  title     = {Limit loads of circumferentially flawed pipes and cylindrical vessels under internal pressure},
  series = {International Journal of Pressure Vessels and Piping. 83 (2006), H. 3},
  journal   = {International Journal of Pressure Vessels and Piping. 83 (2006), H. 3},
  isbn      = {0308-0161},
  pages     = {188 -- 196},
  year      = {2006},
  language  = {en}
}
@incollection{TranTranMatthiesetal.2017,
  author    = {Tran, N. T. and Tran, Thanh Ngoc and Matthies, M. G. and Stavroulakis, G. E. and Staat, Manfred},
  title     = {Shakedown Analysis Under Stochastic Uncertainty by Chance Constrained Programming},
  series = {Advances in Direct Methods for Materials and Structures},
  booktitle = {Advances in Direct Methods for Materials and Structures},
  publisher = {Springer},
  address   = {Cham},
  isbn      = {978-3-319-59810-9},
  doi       = {10.1007/978-3-319-59810-9_6},
  pages     = {85 -- 103},
  year      = {2017},
  abstract  = {In this paper we propose a stochastic programming method to analyse limit and shakedown of structures under uncertainty condition of strength. Based on the duality theory, the shakedown load multiplier formulated by the kinematic theorem is proved actually to be the dual form of the shakedown load multiplier formulated by static theorem. In this investigation a dual chance constrained programming algorithm is developed to calculate simultaneously both the upper and lower bounds of the plastic collapse limit and the shakedown limit. The edge-based smoothed finite element method (ES-FEM) with three-node linear triangular elements is used for structural analysis.},
  language  = {en}
}
@article{JungStaat2020,
  author    = {Jung, Alexander and Staat, Manfred},
  title     = {Erratum to "Modeling and simulation of human induced pluripotent stem cell-derived cardiac tissue" [GAMM-Mitteilungen, (2019), 42, 4, 10.1002/gamm.201900002]},
  series = {GAMM-Mitteilungen},
  volume    = {43},
  journal   = {GAMM-Mitteilungen},
  number    = {4},
  publisher = {Wiley-VCH GmbH},
  address   = {Weinheim},
  issn      = {1522-2608},
  doi       = {10.1002/gamm.202000011},
  year      = {2020},
  language  = {en}
}
@inproceedings{BhattaraiStaat2018,
  author    = {Bhattarai, Aroj and Staat, Manfred},
  title     = {Pectopexy to repair vaginal vault prolapse: a finite element approach},
  series = {Proceedings CMBBE 2018},
  booktitle = {Proceedings CMBBE 2018},
  editor    = {Fernandes, P.R. and Tavares, J. M.},
  year      = {2018},
  abstract  = {The vaginal prolapse after hysterectomy (removal of the uterus) is often associated with the prolapse of the vaginal vault, rectum, bladder, urethra or small bowel. Minimally invasive surgery such as laparoscopic sacrocolpopexy and pectopexy are widely performed for the treatment of the vaginal prolapse with weakly supported vaginal vault after hysterectomy using prosthetic mesh implants to support (or strengthen) lax apical ligaments. Implants of different shape, size and polymers are selected depending on the patient's anatomy and the surgeon's preference. In this computational study on pectopexy, DynaMesh®-PRP soft, GYNECARE GYNEMESH® PS Nonabsorbable PROLENE® soft and Ultrapro® are tested in a 3D finite element model of the female pelvic floor. The mesh model is implanted into the extraperitoneal space and sutured to the vaginal stump with a bilateral fixation to the iliopectineal ligament at both sides. Numerical simulations are conducted at rest, after surgery and during Valsalva maneuver with weakened tissues modeled by reduced tissue stiffness. Tissues and prosthetic meshes are modeled as incompressible, isotropic hyperelastic materials. The positions of the organs are calculated with respect to the pubococcygeal line (PCL) for female pelvic floor at rest, after repair and during Valsalva maneuver using the three meshes.},
  language  = {en}
}
@inproceedings{JungStaat2016,
  author    = {Jung, Alexander and Staat, Manfred},
  title     = {Computing olympic gold: Ski jumping as an example},
  series = {1st YRA MedTech Symposium 2016 : April 8th / 2016 / University of Duisburg-Essen},
  booktitle = {1st YRA MedTech Symposium 2016 : April 8th / 2016 / University of Duisburg-Essen},
  editor    = {Erni, Daniel},
  publisher = {Universit{\"a}t Duisburg-Essen},
  address   = {Duisburg},
  organization    = {MedTech Symposium},
  isbn      = {978-3-940402-06-6},
  doi       = {10.17185/duepublico/40821},
  pages     = {54 -- 55},
  year      = {2016},
  language  = {en}
}
@article{LehnertzBialonskiHorstmannetal.2009,
  author    = {Lehnertz, Klaus and Bialonski, Stephan and Horstmann, Marie-Therese and Krug, Dieter and Rothkegel, Alexander and Staniek, Matth{\"a}us and Wagner, Tobias},
  title     = {Synchronization phenomena in human epileptic brain networks},
  series = {Journal of neuroscience methods},
  volume    = {183},
  journal   = {Journal of neuroscience methods},
  number    = {1},
  issn      = {0165-0270},
  doi       = {10.1016/j.jneumeth.2009.05.015},
  pages     = {42 -- 48},
  year      = {2009},
  language  = {en}
}
@article{StaatVu2007,
  author    = {Staat, Manfred and Vu, Duc-Khoi},
  title     = {Limit analysis of flaws in pressurized pipes and cylindrical vessels. Part I: Axial defects},
  series = {Engineering Fracture Mechanics. 74 (2007), H. 3},
  journal   = {Engineering Fracture Mechanics. 74 (2007), H. 3},
  isbn      = {0013-7944},
  pages     = {431 -- 450},
  year      = {2007},
  language  = {en}
}
@article{VantStaatBaroud2008,
  author    = {Vant, Christianne and Staat, Manfred and Baroud, Gamal},
  title     = {Percutaneous Vertebroplasty: A Review of Two Intraoperative Complications},
  series = {Bioengineering in Cell and Tissue Research / Artmann, Gerhard M. ; Chien, Shu (Eds.)},
  journal   = {Bioengineering in Cell and Tissue Research / Artmann, Gerhard M. ; Chien, Shu (Eds.)},
  publisher = {Springer},
  address   = {Berlin},
  isbn      = {978-3-540-75408-4},
  pages     = {527 -- 539},
  year      = {2008},
  language  = {en}
}
@article{VuStaat2007,
  author    = {Vu, Duc Khoi and Staat, Manfred},
  title     = {Shakedown analysis of structures made of materials with temperature-dependent yield stress},
  series = {International Journal of Solids and Structures. 44 (2007), H. 13},
  journal   = {International Journal of Solids and Structures. 44 (2007), H. 13},
  isbn      = {0020-7683},
  pages     = {4524 -- 4540},
  year      = {2007},
  language  = {en}
}
@incollection{KnottSofroniaGerressenetal.2014,
  author    = {Knott, Thomas C. and Sofronia, Raluca E. and Gerressen, Marcus and Law, Yuen and Davidescu, Arjana and Savii, George G. and Gatzweiler, Karl-Heinz and Staat, Manfred and Kuhlen, Torsten W.},
  title     = {Preliminary bone sawing model for a virtual reality-based training simulator of bilateral sagittal split osteotomy},
  series = {Biomedical simulation : 6th International Symposium, ISBMS 2014, Strasbourg, France, October 16-17, 2014 : proceedings (Lecture notes in computer science : vol. 8789)},
  booktitle = {Biomedical simulation : 6th International Symposium, ISBMS 2014, Strasbourg, France, October 16-17, 2014 : proceedings (Lecture notes in computer science : vol. 8789)},
  publisher = {Springer},
  address   = {Cham},
  isbn      = {978-3-319-12057-7 (Online)},
  doi       = {10.1007/978-3-319-12057-7_1},
  pages     = {1 -- 10},
  year      = {2014},
  abstract  = {Successful bone sawing requires a high level of skill and experience, which could be gained by the use of Virtual Reality-based simulators. A key aspect of these medical simulators is realistic force feedback. The aim of this paper is to model the bone sawing process in order to develop a valid training simulator for the bilateral sagittal split osteotomy, the most often applied corrective surgery in case of a malposition of the mandible. Bone samples from a human cadaveric mandible were tested using a designed experimental system. Image processing and statistical analysis were used for the selection of four models for the bone sawing process. The results revealed a polynomial dependency between the material removal rate and the applied force. Differences between the three segments of the osteotomy line and between the cortical and cancellous bone were highlighted.},
  language  = {en}
}
@article{WarerkarSchmitzGoettscheetal.2011,
  author    = {Warerkar, Shashikant and Schmitz, Stefan and G{\"o}ttsche, Joachim and Hoffschmidt, Bernhard and Reißel, Martin and Tamme, Rainer},
  title     = {Air-Sand Heat Exchanger for High-Temperature Storage},
  series = {Journal of Solar Energy Engineering. 133 (2011), H. 2},
  journal   = {Journal of Solar Energy Engineering. 133 (2011), H. 2},
  publisher = {ASME},
  address   = {New York},
  isbn      = {0199-6231},
  pages     = {021010},
  year      = {2011},
  language  = {en}
}
@article{DoorschodtSchreinemachersBehbahanietal.2011,
  author    = {Doorschodt, B. M. and Schreinemachers, M. C. J. M. and Behbahani, Mehdi and Florquin, S. and Weis, J. and Staat, Manfred and Tolba, R. H.},
  title     = {Hypothermic machine perfusion of kidney grafts: which pressure is preferred},
  series = {Annals of Biomedical Engineering. 39 (2011), H. 3},
  journal   = {Annals of Biomedical Engineering. 39 (2011), H. 3},
  publisher = {Springer},
  address   = {Berlin},
  isbn      = {1573-9686},
  pages     = {1051 -- 1059},
  year      = {2011},
  language  = {en}
}
@article{DigelZerlinTemizArtmannetal.2007,
  author    = {Digel, Ilya and Zerlin, Kay and Temiz Artmann, Ayseg{\"u}l and Engels, S.},
  title     = {Protein dynamics in thermosensation},
  series = {Regenerative medicine. 2 (2007), H. 5},
  journal   = {Regenerative medicine. 2 (2007), H. 5},
  isbn      = {1746-0751},
  pages     = {533 -- 533},
  year      = {2007},
  language  = {en}
}
@article{BhattaraiStaat2018,
  author    = {Bhattarai, Aroj and Staat, Manfred},
  title     = {Modelling of Soft Connective Tissues to Investigate Female Pelvic Floor Dysfunctions},
  series = {Computational and Mathematical Methods in Medicine},
  volume    = {2018},
  journal   = {Computational and Mathematical Methods in Medicine},
  number    = {Article ID 9518076},
  publisher = {Hindawi},
  address   = {New York, NY},
  issn      = {1748-6718},
  doi       = {10.1155/2018/9518076},
  pages     = {1 -- 16},
  year      = {2018},
  abstract  = {After menopause, decreased levels of estrogen and progesterone remodel the collagen of the soft tissues thereby reducing their stiffness. Stress urinary incontinence is associated with involuntary urine leakage due to pathological movement of the pelvic organs resulting from lax suspension system, fasciae, and ligaments. This study compares the changes in the orientation and position of the female pelvic organs due to weakened fasciae, ligaments, and their combined laxity. A mixture theory weighted by respective volume fraction of elastin-collagen fibre compound (5\%), adipose tissue (85\%), and smooth muscle (5\%) is adopted to characterize the mechanical behaviour of the fascia. The load carrying response (other than the functional response to the pelvic organs) of each fascia component, pelvic organs, muscles, and ligaments are assumed to be isotropic, hyperelastic, and incompressible. Finite element simulations are conducted during Valsalva manoeuvre with weakened tissues modelled by reduced tissue stiffness. A significant dislocation of the urethrovesical junction is observed due to weakness of the fascia (13.89 mm) compared to the ligaments (5.47 mm). The dynamics of the pelvic floor observed in this study during Valsalva manoeuvre is associated with urethral-bladder hypermobility, greater levator plate angulation, and positive Q-tip test which are observed in incontinent females.},
  language  = {en}
}
@article{ColomboDriraFrotscheretal.2022,
  author    = {Colombo, Daniele and Drira, Slah and Frotscher, Ralf and Staat, Manfred},
  title     = {An element-based formulation for ES-FEM and FS-FEM models for implementation in standard solid mechanics finite element codes for 2D and 3D static analysis},
  series = {International Journal for Numerical Methods in Engineering},
  volume    = {124},
  journal   = {International Journal for Numerical Methods in Engineering},
  number    = {2},
  publisher = {Wiley},
  address   = {Chichester},
  issn      = {1097-0207},
  doi       = {10.1002/nme.7126},
  pages     = {402 -- 433},
  year      = {2022},
  abstract  = {Edge-based and face-based smoothed finite element methods (ES-FEM and FS-FEM, respectively) are modified versions of the finite element method allowing to achieve more accurate results and to reduce sensitivity to mesh distortion, at least for linear elements. These properties make the two methods very attractive. However, their implementation in a standard finite element code is nontrivial because it requires heavy and extensive modifications to the code architecture. In this article, we present an element-based formulation of ES-FEM and FS-FEM methods allowing to implement the two methods in a standard finite element code with no modifications to its architecture. Moreover, the element-based formulation permits to easily manage any type of element, especially in 3D models where, to the best of the authors' knowledge, only tetrahedral elements are used in FS-FEM applications found in the literature. Shape functions for non-simplex 3D elements are proposed in order to apply FS-FEM to any standard finite element.},
  language  = {en}
}
@article{SavitskayaKistaubayevaIgnatovaetal.2019,
  author    = {Savitskaya, I.S. and Kistaubayeva, A.S. and Ignatova, L.V. and Digel, Ilya},
  title     = {Antimicrobial and wound healing properties of a bacterial cellulose based material containing B. subtilis cells},
  series = {Heliyon},
  volume    = {5},
  journal   = {Heliyon},
  number    = {10},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {2405-8440},
  doi       = {10.1016/j.heliyon.2019.e02592},
  pages     = {Artikelnummer e02592},
  year      = {2019},
  language  = {en}
}
@article{NguyenDuongTranetal.2012,
  author    = {Nguyen, Nhu Huynh and Duong, Minh Tuan and Tran, Thanh Ngoc and Pham, Phu Tinh and Grottke, O. and Tolba, R. and Staat, Manfred},
  title     = {Influence of a freeze-thaw cycle on the stress-stretch curves of tissues of porcine abdominal organs},
  series = {Journal of Biomechanics},
  volume    = {45},
  journal   = {Journal of Biomechanics},
  number    = {14},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1873-2380},
  doi       = {10.1016/j.jbiomech.2012.07.008},
  pages     = {2382 -- 2386},
  year      = {2012},
  abstract  = {The paper investigates both fresh porcine spleen and liver and the possible decomposition of these organs under a freeze-thaw cycle. The effect of tissue preservation condition is an important factor which should be taken into account for protracted biomechanical tests. In this work, tension tests were conducted for a large number of tissue specimens from twenty pigs divided into two groups of 10. Concretely, the first group was tested in fresh state; the other one was tested after a freeze-thaw cycle which simulates the conservation conditions before biomechanical experiments. A modified Fung model for isotropic behavior was adopted for the curve fitting of each kind of tissues. Experimental results show strong effects of the realistic freeze-thaw cycle on the capsule of elastin-rich spleen but negligible effects on the liver which virtually contains no elastin. This different behavior could be explained by the autolysis of elastin by elastolytic enzymes during the warmer period after thawing. Realistic biomechanical properties of elastin-rich organs can only be expected if really fresh tissue is tested. The observations are supported by tests of intestines.},
  language  = {en}
}
@article{StaatTrenzLohmannetal.2012,
  author    = {Staat, Manfred and Trenz, Eva and Lohmann, Philipp and Frotscher, Ralf and Klinge, Uwe and Tabaza, Ruth and Kirschner-Hermanns, Ruth},
  title     = {New measurements to compare soft tissue anchoring systems in pelvic floor surgery},
  series = {Journal of Biomedical Materials Research Part B: Applied Biomaterials},
  volume    = {100B},
  journal   = {Journal of Biomedical Materials Research Part B: Applied Biomaterials},
  number    = {4},
  publisher = {Wiley},
  address   = {Hoboken, NJ},
  issn      = {1552-4981},
  doi       = {10.1002/jbm.b.32654},
  pages     = {924 -- 933},
  year      = {2012},
  abstract  = {Suburethral slings as well as different meshes are widely used treating stress urinary incontinence and prolaps in women. With the development of MiniSlings and special meshes using less alloplastic material anchorage systems become more important to keep devices in place and to put some tension especially on the MiniSlings. To date, there are many different systems of MiniSlings of different companies on the market which differ in the structure of the used meshes and anchors. A new objective measurement method to compare different properties of MiniSling systems (mesh and anchor) is presented in this article. Ballistic gelatine acts as soft tissue surrogate. Significant differences in parameters like pull-out strength of anchors or shrinkage of meshes under loading conditions have been determined. The form and size of the anchors as well as the structural stability of the meshes are decisive for a proper integration. The tested anchorings sytems showed markedly different mechanical function at their respective load bearing capacity. As the stable fixation of the device in tissue is a prerequisite for a permanet reinforcement, the proposed test system permits further optimisation of anchor and mesh devices to improve the success of the surgical treatment},
  language  = {en}
}
@article{NovacekTranKlingeetal.2012,
  author    = {Novacek, V. and Tran, Thanh Ngoc and Klinge, U. and Tolba, R. H. and Staat, Manfred and Bronson, D. G. and Miesse, A. M. and Whiffen, J. and Turquier, F.},
  title     = {Finite element modelling of stapled colorectal end-to-end anastomosis : Advantages of variable height stapler design},
  series = {Journal of Biomechanics},
  volume    = {45},
  journal   = {Journal of Biomechanics},
  number    = {115},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1873-2380},
  doi       = {10.1016/j.jbiomech.2012.07.021},
  pages     = {2693 -- 2697},
  year      = {2012},
  abstract  = {The impact of surgical staplers on tissues has been studied mostly in an empirical manner. In this paper, finite element method was used to clarify the mechanics of tissue stapling and associated phenomena. Various stapling modalities and several designs of circular staplers were investigated to evaluate the impact of the device on tissues and mechanical performance of the end-to-end colorectal anastomosis. Numerical simulations demonstrated that a single row of staples is not adequate to resist leakage due to non-linear buckling and opening of the tissue layers between two adjacent staples. Compared to the single staple row configuration, significant increase in stress experienced by the tissue at the inner staple rows was observed in two and three rows designs. On the other hand, adding second and/or third staple row had no effect on strain in the tissue inside the staples. Variable height design with higher staples in outer rows significantly reduced the stresses and strains in outer rows when compared to the same configuration with flat cartridge.},
  language  = {en}
}
@article{StaatHeitzer2003,
  author    = {Staat, Manfred and Heitzer, M.},
  title     = {Probabilistic limit and shakedown problems},
  series = {Numerical Methods for Limit and Shakedown Analysis. Deterministic and Probabilistic Approach. NIC Series Vol. 15 / Ed. by Staat, M; Heitzer, M.},
  journal   = {Numerical Methods for Limit and Shakedown Analysis. Deterministic and Probabilistic Approach. NIC Series Vol. 15 / Ed. by Staat, M; Heitzer, M.},
  publisher = {John von Neumann Institute for Computing (NIC)},
  address   = {J{\"u}lich},
  isbn      = {3-00-010001-6},
  pages     = {217 -- 268},
  year      = {2003},
  language  = {en}
}
@inproceedings{FrotscherGossmannTemizArtmannetal.2013,
  author    = {Frotscher, Ralf and Goßmann, Matthias and Temiz Artmann, Ayseg{\"u}l and Staat, Manfred},
  title     = {Simulation of cardiac cell-seeded membranes using the edge-based smoothed FEM},
  series = {1st International Conference "Shell and Membrane Theories in Mechanics and Biology: From Macro- to Nanoscale Structures", Minsk, Belarus, Sept. 16-20, 2013},
  booktitle = {1st International Conference "Shell and Membrane Theories in Mechanics and Biology: From Macro- to Nanoscale Structures", Minsk, Belarus, Sept. 16-20, 2013},
  publisher = {Verl. d. Weißruss. Staatl. Univ.},
  address   = {Minsk},
  organization    = {International Conference Shell and Membrane Theories in Mechanics and Biology: From Macro- to Nanoscale Structures <1, 2013, Minsk>},
  isbn      = {978-985-553-135-8},
  pages     = {165 -- 167},
  year      = {2013},
  language  = {en}
}
@article{GeierBialonskiElgeretal.2015,
  author    = {Geier, Christian and Bialonski, Stephan and Elger, Christian E. and Lehnertz, Klaus},
  title     = {How important is the seizure onset zone for seizure dynamics?},
  series = {Seizure},
  volume    = {25},
  journal   = {Seizure},
  issn      = {1059-1311},
  doi       = {10.1016/j.seizure.2014.10.013},
  pages     = {160 -- 166},
  year      = {2015},
  language  = {en}
}
@incollection{DigelAkimbekovKistaubayevaetal.2018,
  author    = {Digel, Ilya and Akimbekov, Nuraly S. and Kistaubayeva, Aida and Zhubanova, Azhar A.},
  title     = {Microbial Sampling from Dry Surfaces: Current Challenges and Solutions},
  series = {Biological, Physical and Technical Basics of Cell Engineering},
  booktitle = {Biological, Physical and Technical Basics of Cell Engineering},
  editor    = {Artmann, Gerhard and Temiz Artmann, Ayseg{\"u}l and Zhubanova, Azhar A. and Digel, Ilya},
  publisher = {Springer},
  address   = {Singapore},
  isbn      = {978-981-10-7904-7},
  doi       = {10.1007/978-981-10-7904-7_19},
  pages     = {421 -- 456},
  year      = {2018},
  abstract  = {Sampling of dry surfaces for microorganisms is a main component of microbiological safety and is of critical importance in many fields including epidemiology, astrobiology as well as numerous branches of medical and food manufacturing. Aspects of biofilm formation, analysis and removal in aqueous solutions have been thoroughly discussed in literature. In contrast, microbial communities on air-exposed (dry) surfaces have received significantly less attention. Diverse surface sampling methods have been developed in order to address various surfaces and microbial groups, but they notoriously show poor repeatability, low recovery rates and suffer from lack of mutual consistency. Quantitative sampling for viable microorganisms represents a particular challenge, especially on porous and irregular surfaces. Therefore, it is essential to examine in depth the factors involved in microorganisms' recovery efficiency and accuracy depending on the sampling technique used. Microbial colonization, retention and community composition on different dry surfaces are very complex and rely on numerous physicochemical and biological factors. This study is devoted to analyze and review the (a) physical phenomena and intermolecular forces relevant for microbiological surface sampling; (b) challenges and problems faced by existing sampling methods for viable microorganisms and (c) current directions of engineering and research aimed at improvement of quality and efficiency of microbiological surface sampling.},
  language  = {en}
}
@article{GrajewskiHronTurek2006,
  author    = {Grajewski, Matthias and Hron, Jaroslav and Turek, Stefan},
  title     = {Numerical analysis for a new non-conforming linear finite element on quadrilaterals},
  series = {Journal of Computational and Applied Mathematics},
  volume    = {193},
  journal   = {Journal of Computational and Applied Mathematics},
  number    = {1},
  issn      = {0377-0427},
  doi       = {10.1016/j.cam.2005.05.024},
  pages     = {38 -- 50},
  year      = {2006},
  language  = {en}
}
@article{Staat1993,
  author    = {Staat, Manfred},
  title     = {Reliability of the Primary Circuit Pressure Boundary of an HTR-Module under Accident Conditions},
  series = {Safety and reliability assessment : an integral approach ; ESREL'93 ; proceedings of the European Safety and Reliability Conference, Munich, Germany, May 10th - 12th 1993 / Kafka, P. [ed]},
  journal   = {Safety and reliability assessment : an integral approach ; ESREL'93 ; proceedings of the European Safety and Reliability Conference, Munich, Germany, May 10th - 12th 1993 / Kafka, P. [ed]},
  publisher = {Elsevier},
  address   = {Amsterdam},
  isbn      = {0-444-81561-9},
  pages     = {331 -- 342},
  year      = {1993},
  language  = {en}
}
@article{Staat2002,
  author    = {Staat, Manfred},
  title     = {Some Achievements of the European Project LISA for FEM Based Limit and Shakedown Analysis},
  series = {Computational mechanics : developments and applications, 2002 : presented at the 2002 ASME Pressure Vessels and Piping Conference, Vancouver, British Columbia, Canada, August 5 - 9. / Badie, N. [ed]},
  journal   = {Computational mechanics : developments and applications, 2002 : presented at the 2002 ASME Pressure Vessels and Piping Conference, Vancouver, British Columbia, Canada, August 5 - 9. / Badie, N. [ed]},
  publisher = {American Society of Mechanical Engineers},
  address   = {New York},
  isbn      = {0791846520},
  pages     = {177 -- 185},
  year      = {2002},
  language  = {en}
}
@article{StaatHeitzerReinersetal.2003,
  author    = {Staat, Manfred and Heitzer, M. and Reiners, H. and Schubert, F.},
  title     = {Shakedown and ratchetting under tension-torsion loadings: analysis and experiments},
  series = {Nuclear Engineering and Design. 225 (2003), H. 1},
  journal   = {Nuclear Engineering and Design. 225 (2003), H. 1},
  isbn      = {0029-5493},
  pages     = {11 -- 26},
  year      = {2003},
  language  = {en}
}
@incollection{StaatHeitzer2003,
  author    = {Staat, Manfred and Heitzer, M.},
  title     = {Basis reduction technique for limit and shakedown problems},
  series = {Numerical Methods for Limit and Shakedown Analysis. Deterministic and Probabilistic Approach. NIC Series Vol. 15 / Ed. by Staat, M.; Heitzer, M.},
  booktitle = {Numerical Methods for Limit and Shakedown Analysis. Deterministic and Probabilistic Approach. NIC Series Vol. 15 / Ed. by Staat, M.; Heitzer, M.},
  publisher = {John von Neumann Institute for Computing (NIC)},
  address   = {J{\"u}lich},
  isbn      = {3-00-010001-6},
  url       = {http://nbn-resolving.de/urn:nbn:de:0001-2018112115},
  pages     = {1 -- 55},
  year      = {2003},
  language  = {en}
}
@article{StadlerDigelArtmannetal.2008,
  author    = {Stadler, A. M. and Digel, Ilya and Artmann, Gerhard and Embs, Jan P. and Zaccai, Joe and B{\"u}ldt, Georg},
  title     = {Hemoglobin Dynamics in Red Blood Cells: Correlation to Body Temperature},
  series = {Biophysical Journal. 95 (2008), H. 11},
  journal   = {Biophysical Journal. 95 (2008), H. 11},
  isbn      = {1542-0086},
  pages     = {5449 -- 5461},
  year      = {2008},
  language  = {en}
}
@article{TranKreissigStaat2009,
  author    = {Tran, Thanh Ngoc and Kreißig, R. and Staat, Manfred},
  title     = {Probabilistic limit and shakedown analysis of thin plates and shells},
  series = {Structural safety. 31 (2009), H. 1},
  journal   = {Structural safety. 31 (2009), H. 1},
  publisher = {-},
  isbn      = {0167-4730},
  pages     = {1 -- 18},
  year      = {2009},
  language  = {en}
}
@article{StaatTranKreissig2008,
  author    = {Staat, Manfred and Tran, Thanh Ngoc and Kreißig, R.},
  title     = {Load bearing capacity of thin shell structures made of elastoplastic material by direct methods},
  series = {Technische Mechanik. 28 (2008), H. 3-4},
  journal   = {Technische Mechanik. 28 (2008), H. 3-4},
  pages     = {299 -- 309},
  year      = {2008},
  language  = {en}
}
@article{StaatBallmann1988,
  author    = {Staat, Manfred and Ballmann, J.},
  title     = {Wave Propagation and Focussing in Plates},
  series = {Impact loading and dynamic behaviour of materials : Papers presented at the International Conference on Impact Loading and Dynamic Behaviour of Materials, Vol. 2 / Chiem, C. Y.; Kunze, L. (u.a.) [eds]},
  journal   = {Impact loading and dynamic behaviour of materials : Papers presented at the International Conference on Impact Loading and Dynamic Behaviour of Materials, Vol. 2 / Chiem, C. Y.; Kunze, L. (u.a.) [eds]},
  publisher = {DGM Informationsges.},
  address   = {Oberursel},
  year      = {1988},
  language  = {en}
}
@article{TranPhamVuetal.2009,
  author    = {Tran, Thanh Ngoc and Pham, Phu Tinh and Vu, D. K. and Staat, Manfred},
  title     = {Reliability Analysis of Inelastic Shell Structures Under Variable Loads},
  series = {Limit States of Materials and Structures : Direct Methods / Hrsg. Dieter Weichert; Hrsg. Alan Ponter},
  journal   = {Limit States of Materials and Structures : Direct Methods / Hrsg. Dieter Weichert; Hrsg. Alan Ponter},
  publisher = {Springer Netherland},
  address   = {Berlin},
  isbn      = {978-1-4020-9633-4},
  pages     = {135 -- 156},
  year      = {2009},
  language  = {en}
}
@article{Laack2013,
  author    = {Laack, Walter van},
  title     = {The genetic code should be seen as a positioning code},
  series = {British journal of arts and social sciences. Vol. 14 (2013), No. 1},
  journal   = {British journal of arts and social sciences. Vol. 14 (2013), No. 1},
  issn      = {2046-9578},
  pages     = {93 -- 97},
  year      = {2013},
  language  = {en}
}
@incollection{OsterhageBialonskiStanieketal.2008,
  author    = {Osterhage, Hannes and Bialonski, Stephan and Staniek, Matth{\"a}us and Schindler, Kaspar and Wagner, Tobias and Elger, Christian E. and Lehnertz, Klaus},
  title     = {Bivariate and multivariate time series analysis techniques and their potential impact for seizure prediction},
  series = {Seizure Prediction in Epilepsy: From Basic Mechanisms to Clinical Applications},
  booktitle = {Seizure Prediction in Epilepsy: From Basic Mechanisms to Clinical Applications},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  isbn      = {978-3-527-62519-2},
  doi       = {10.1002/9783527625192.ch15},
  pages     = {189 -- 208},
  year      = {2008},
  language  = {en}
}