@article{DachwaldMcDonaldMcInnesetal.2007,
  author    = {Dachwald, Bernd and McDonald, Malcolm and McInnes, Colin R. and Mengali, Giovanni},
  title     = {Impact of Optical Degradation on Solar Sail Mission Performance},
  series = {Journal of Spacecraft and Rockets. 44 (2007), H. 4},
  journal   = {Journal of Spacecraft and Rockets. 44 (2007), H. 4},
  isbn      = {0022-4650},
  pages     = {740 -- 749},
  year      = {2007},
  language  = {en}
}
@article{NguyenDuongTranetal.2012,
  author    = {Nguyen, Nhu Huynh and Duong, Minh Tuan and Tran, Thanh Ngoc and Pham, Phu Tinh and Grottke, O. and Tolba, R. and Staat, Manfred},
  title     = {Influence of a freeze-thaw cycle on the stress-stretch curves of tissues of porcine abdominal organs},
  series = {Journal of Biomechanics},
  volume    = {45},
  journal   = {Journal of Biomechanics},
  number    = {14},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1873-2380},
  doi       = {10.1016/j.jbiomech.2012.07.008},
  pages     = {2382 -- 2386},
  year      = {2012},
  abstract  = {The paper investigates both fresh porcine spleen and liver and the possible decomposition of these organs under a freeze-thaw cycle. The effect of tissue preservation condition is an important factor which should be taken into account for protracted biomechanical tests. In this work, tension tests were conducted for a large number of tissue specimens from twenty pigs divided into two groups of 10. Concretely, the first group was tested in fresh state; the other one was tested after a freeze-thaw cycle which simulates the conservation conditions before biomechanical experiments. A modified Fung model for isotropic behavior was adopted for the curve fitting of each kind of tissues. Experimental results show strong effects of the realistic freeze-thaw cycle on the capsule of elastin-rich spleen but negligible effects on the liver which virtually contains no elastin. This different behavior could be explained by the autolysis of elastin by elastolytic enzymes during the warmer period after thawing. Realistic biomechanical properties of elastin-rich organs can only be expected if really fresh tissue is tested. The observations are supported by tests of intestines.},
  language  = {en}
}
@article{StaatTrenzLohmannetal.2012,
  author    = {Staat, Manfred and Trenz, Eva and Lohmann, Philipp and Frotscher, Ralf and Klinge, Uwe and Tabaza, Ruth and Kirschner-Hermanns, Ruth},
  title     = {New measurements to compare soft tissue anchoring systems in pelvic floor surgery},
  series = {Journal of Biomedical Materials Research Part B: Applied Biomaterials},
  volume    = {100B},
  journal   = {Journal of Biomedical Materials Research Part B: Applied Biomaterials},
  number    = {4},
  publisher = {Wiley},
  address   = {Hoboken, NJ},
  issn      = {1552-4981},
  doi       = {10.1002/jbm.b.32654},
  pages     = {924 -- 933},
  year      = {2012},
  abstract  = {Suburethral slings as well as different meshes are widely used treating stress urinary incontinence and prolaps in women. With the development of MiniSlings and special meshes using less alloplastic material anchorage systems become more important to keep devices in place and to put some tension especially on the MiniSlings. To date, there are many different systems of MiniSlings of different companies on the market which differ in the structure of the used meshes and anchors. A new objective measurement method to compare different properties of MiniSling systems (mesh and anchor) is presented in this article. Ballistic gelatine acts as soft tissue surrogate. Significant differences in parameters like pull-out strength of anchors or shrinkage of meshes under loading conditions have been determined. The form and size of the anchors as well as the structural stability of the meshes are decisive for a proper integration. The tested anchorings sytems showed markedly different mechanical function at their respective load bearing capacity. As the stable fixation of the device in tissue is a prerequisite for a permanet reinforcement, the proposed test system permits further optimisation of anchor and mesh devices to improve the success of the surgical treatment},
  language  = {en}
}
@article{KonstantinidisFloresMartinezDachwaldetal.2015,
  author    = {Konstantinidis, Konstantinos and Flores Martinez, Claudio and Dachwald, Bernd and Ohndorf, Andreas and Dykta, Paul and Bowitz, Pascal and Rudolph, Martin and Digel, Ilya and Kowalski, Julia and Voigt, Konstantin and F{\"o}rstner, Roger},
  title     = {A lander mission to probe subglacial water on Saturn's moon enceladus for life},
  series = {Acta astronautica},
  volume    = {Vol. 106},
  journal   = {Acta astronautica},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1879-2030 (E-Journal); 0094-5765 (Print)},
  pages     = {63 -- 89},
  year      = {2015},
  language  = {en}
}
@article{NovacekTranKlingeetal.2012,
  author    = {Novacek, V. and Tran, Thanh Ngoc and Klinge, U. and Tolba, R. H. and Staat, Manfred and Bronson, D. G. and Miesse, A. M. and Whiffen, J. and Turquier, F.},
  title     = {Finite element modelling of stapled colorectal end-to-end anastomosis : Advantages of variable height stapler design},
  series = {Journal of Biomechanics},
  volume    = {45},
  journal   = {Journal of Biomechanics},
  number    = {115},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1873-2380},
  doi       = {10.1016/j.jbiomech.2012.07.021},
  pages     = {2693 -- 2697},
  year      = {2012},
  abstract  = {The impact of surgical staplers on tissues has been studied mostly in an empirical manner. In this paper, finite element method was used to clarify the mechanics of tissue stapling and associated phenomena. Various stapling modalities and several designs of circular staplers were investigated to evaluate the impact of the device on tissues and mechanical performance of the end-to-end colorectal anastomosis. Numerical simulations demonstrated that a single row of staples is not adequate to resist leakage due to non-linear buckling and opening of the tissue layers between two adjacent staples. Compared to the single staple row configuration, significant increase in stress experienced by the tissue at the inner staple rows was observed in two and three rows designs. On the other hand, adding second and/or third staple row had no effect on strain in the tissue inside the staples. Variable height design with higher staples in outer rows significantly reduced the stresses and strains in outer rows when compared to the same configuration with flat cartridge.},
  language  = {en}
}
@article{Staat2005,
  author    = {Staat, Manfred},
  title     = {Direct finite element route for design-by-analysis of pressure components},
  year      = {2005},
  abstract  = {In the new European standard for unfired pressure vessels, EN 13445-3, there are two approaches for carrying out a Design-by-Analysis that cover both the stress categorization method (Annex C) and the direct route method (Annex B) for a check against global plastic deformation and against progressive plastic deformation. This paper presents the direct route in the language of limit and shakedown analysis. This approach leads to an optimization problem. Its solution with Finite Element Analysis is demonstrated for mechanical and thermal actions. One observation from the examples is that the so-called 3f (3Sm) criterion fails to be a reliable check against progressive plastic deformation. Precise conditions are given, which greatly restrict the applicability of the 3f criterion.},
  subject      = {Einspielen <Werkstoff>},
  language  = {en}
}
@article{HacklWegmannKahmannetal.2017,
  author    = {Hackl, Michael and Wegmann, Kilian and Kahmann, Stephanie Lucina and Heinze, Nicolai and Staat, Manfred and Neiss, Wolfram F. and Scaal, Martin and M{\"u}ller, Lars P.},
  title     = {Radial shortening osteotomy reduces radiocapitellar contact pressures while preserving valgus stability of the elbow},
  series = {Knee Surgery, Sports Traumatology, Arthroscopy},
  volume    = {25},
  journal   = {Knee Surgery, Sports Traumatology, Arthroscopy},
  number    = {7},
  publisher = {Springer},
  address   = {Berlin},
  issn      = {1433-7347},
  doi       = {10.1007/s00167-017-4468-z},
  pages     = {2280 -- 2288},
  year      = {2017},
  language  = {en}
}
@article{StaatHeitzer2003,
  author    = {Staat, Manfred and Heitzer, M.},
  title     = {Probabilistic limit and shakedown problems},
  series = {Numerical Methods for Limit and Shakedown Analysis. Deterministic and Probabilistic Approach. NIC Series Vol. 15 / Ed. by Staat, M; Heitzer, M.},
  journal   = {Numerical Methods for Limit and Shakedown Analysis. Deterministic and Probabilistic Approach. NIC Series Vol. 15 / Ed. by Staat, M; Heitzer, M.},
  publisher = {John von Neumann Institute for Computing (NIC)},
  address   = {J{\"u}lich},
  isbn      = {3-00-010001-6},
  pages     = {217 -- 268},
  year      = {2003},
  language  = {en}
}
@article{DachwaldUlamecPostbergetal.2020,
  author    = {Dachwald, Bernd and Ulamec, Stephan and Postberg, Frank and Sohl, Frank and Vera, Jean-Pierre de and Christoph, Waldmann and Lorenz, Ralph D. and Hellard, Hugo and Biele, Jens and Rettberg, Petra},
  title     = {Key technologies and instrumentation for subsurface exploration of ocean worlds},
  series = {Space Science Reviews},
  volume    = {216},
  journal   = {Space Science Reviews},
  number    = {Art. 83},
  publisher = {Springer},
  address   = {Dordrecht},
  issn      = {1572-9672},
  doi       = {10.1007/s11214-020-00707-5},
  pages     = {45},
  year      = {2020},
  abstract  = {In this chapter, the key technologies and the instrumentation required for the subsurface exploration of ocean worlds are discussed. The focus is laid on Jupiter's moon Europa and Saturn's moon Enceladus because they have the highest potential for such missions in the near future. The exploration of their oceans requires landing on the surface, penetrating the thick ice shell with an ice-penetrating probe, and probably diving with an underwater vehicle through dozens of kilometers of water to the ocean floor, to have the chance to find life, if it exists. Technologically, such missions are extremely challenging. The required key technologies include power generation, communications, pressure resistance, radiation hardness, corrosion protection, navigation, miniaturization, autonomy, and sterilization and cleaning. Simpler mission concepts involve impactors and penetrators or - in the case of Enceladus - plume-fly-through missions.},
  language  = {en}
}
@article{HacklKahmannWegmannetal.2016,
  author    = {Hackl, Michael and Kahmann, Stephanie Lucina and Wegmann, Kilian and Ries, Christian and Staat, Manfred and M{\"u}ller, Lars-Peter},
  title     = {Shortening osteotomy of the proximal radius — a treatment option for isolated osteoarthritis of the lateral column of the elbow joint?},
  series = {Knee surgery, sports traumatology, arthroscopy},
  volume    = {Volume 24},
  journal   = {Knee surgery, sports traumatology, arthroscopy},
  number    = {Supplement 1},
  publisher = {Springer},
  address   = {Berlin},
  issn      = {0942-2056},
  doi       = {10.1007/s00167-016-4080-7},
  pages     = {128 -- 129},
  year      = {2016},
  abstract  = {Treatment of posttraumatic osteoarthritis of the radial column of the elbow joint remains a challenging yet common issue. While partial joint replacement leads to high revision rates, radial head excision has shown to severely increase joint instability. Shortening osteotomy of the radius could be an option to decrease the contact pressure of the radiohumeral joint and thereby pain levels without causing valgus instability. Hence, the aim of this biomechanical study was to evaluate the effects of radial shortening on axial load distribution and valgus stability of the elbow joint.},
  language  = {en}
}
@article{Staat2002,
  author    = {Staat, Manfred},
  title     = {Some Achievements of the European Project LISA for FEM Based Limit and Shakedown Analysis},
  series = {Computational mechanics : developments and applications, 2002 : presented at the 2002 ASME Pressure Vessels and Piping Conference, Vancouver, British Columbia, Canada, August 5 - 9. / Badie, N. [ed]},
  journal   = {Computational mechanics : developments and applications, 2002 : presented at the 2002 ASME Pressure Vessels and Piping Conference, Vancouver, British Columbia, Canada, August 5 - 9. / Badie, N. [ed]},
  publisher = {American Society of Mechanical Engineers},
  address   = {New York},
  isbn      = {0791846520},
  pages     = {177 -- 185},
  year      = {2002},
  language  = {en}
}
@article{StaatHeitzerReinersetal.2003,
  author    = {Staat, Manfred and Heitzer, M. and Reiners, H. and Schubert, F.},
  title     = {Shakedown and ratchetting under tension-torsion loadings: analysis and experiments},
  series = {Nuclear Engineering and Design. 225 (2003), H. 1},
  journal   = {Nuclear Engineering and Design. 225 (2003), H. 1},
  isbn      = {0029-5493},
  pages     = {11 -- 26},
  year      = {2003},
  language  = {en}
}
@article{DachwaldWi2007,
  author    = {Dachwald, Bernd and Wi, Bong},
  title     = {Solar Sail Kinetic Energy Impactor Trajectory Optimization for an Asteroid-Deflection Mission},
  series = {Journal of Spacecraft and Rockets. 44 (2007), H. 4},
  journal   = {Journal of Spacecraft and Rockets. 44 (2007), H. 4},
  isbn      = {0022-4650},
  pages     = {755 -- 764},
  year      = {2007},
  language  = {en}
}
@article{Dachwald2004,
  author    = {Dachwald, Bernd},
  title     = {Minimum Transfer Times for Nonperfectly Reflecting Solar Sailcraft},
  series = {Journal of Spacecraft and Rockets. 41 (2004), H. 4},
  journal   = {Journal of Spacecraft and Rockets. 41 (2004), H. 4},
  isbn      = {0022-4650},
  pages     = {693 -- 695},
  year      = {2004},
  language  = {en}
}
@article{EschweilerLaackStaat2007,
  author    = {Eschweiler, J. and Laack, Walter van and Staat, Manfred},
  title     = {Elektromyographische Untersuchungen zur Kr{\"a}ftigung der Oberschenkelmuskulatur mit einem myoelektrischen Stimulator nach arthroskopischen Eingriffen am Kniegelenk},
  series = {Orthop{\"a}dische Praxis. 43 (2007), H. 10},
  journal   = {Orthop{\"a}dische Praxis. 43 (2007), H. 10},
  isbn      = {0030-588x},
  pages     = {539 -- 542},
  year      = {2007},
  language  = {de}
}
@article{MeyerGaalenLeschingeretal.2019,
  author    = {Meyer, Carolin and Gaalen, Kerstin van and Leschinger, Tim and Scheyerer, Max J. and Neiss, Wolfram F. and Staat, Manfred and M{\"u}ller, Lars P. and Wegmann, Kilian},
  title     = {Kyphoplasty of Osteoporotic Fractured Vertebrae: A Finite Element Analysis about Two Types of Cement},
  series = {BioMed Research International},
  journal   = {BioMed Research International},
  doi       = {10.1155/2019/9232813},
  pages     = {Article ID 9232813},
  year      = {2019},
  language  = {en}
}
@article{StadlerDigelArtmannetal.2008,
  author    = {Stadler, A. M. and Digel, Ilya and Artmann, Gerhard and Embs, Jan P. and Zaccai, Joe and B{\"u}ldt, Georg},
  title     = {Hemoglobin Dynamics in Red Blood Cells: Correlation to Body Temperature},
  series = {Biophysical Journal. 95 (2008), H. 11},
  journal   = {Biophysical Journal. 95 (2008), H. 11},
  isbn      = {1542-0086},
  pages     = {5449 -- 5461},
  year      = {2008},
  language  = {en}
}
@article{Dachwald2004,
  author    = {Dachwald, Bernd},
  title     = {Optimization of Interplanetary Solar Sailcraft Trajectories Using Evolutionary Neurocontrol},
  series = {Journal of guidance, control, and dynamics. 27 (2004), H. 1},
  journal   = {Journal of guidance, control, and dynamics. 27 (2004), H. 1},
  isbn      = {0162-3192},
  pages     = {66 -- 72},
  year      = {2004},
  language  = {en}
}
@article{DigelWehlitzKayseretal.2018,
  author    = {Digel, Ilya and Wehlitz, V. and Kayser, Peter and Figiel-Lange, A. and Bassam, R. and Rundstedt, F. von},
  title     = {Suspension depletion approach for exemption of infected Solanum jasminoides cells from pospiviroids},
  series = {Plant Pathology},
  volume    = {67},
  journal   = {Plant Pathology},
  number    = {2},
  publisher = {Wiley},
  address   = {Oxford},
  issn      = {1365-3059},
  doi       = {10.1111/ppa.12750},
  pages     = {358 -- 365},
  year      = {2018},
  abstract  = {Despite numerous studies, viroid elimination from infected plants remains a very challenging task. This study introduces for the first time a novel 'suspension depletion' approach for exemption of Solanum jasminoides plants from viroids. The proposed method implies initial establishment of suspension cultures of the infected plant cells. The suspended cells were then physically treated (mild thermotherapy, 33 °C), which presumably delayed the replication of the viroid. The viroid concentration in the treated biomass was monitored weekly using pospiviroid-specific PCR. After 10-12 weeks of continuous treatment, a sufficient decrease in viroid concentration was observed such that the infection became undetectable by PCR. The treated single cells then gave rise to microcolonies on a solid culture medium and the obtained viroid-negative clones were further promoted to regenerate into viroid-free plants. Three years of accumulated experimental data suggests feasibility, broad applicability, and good efficacy of the proposed approach.},
  language  = {en}
}
@article{DachwaldOhndorfGill2009,
  author    = {Dachwald, Bernd and Ohndorf, A. and Gill, E.},
  title     = {Optimization of low-thrust Earth-Moon transfers using evolutionary neurocontrol / Ohndorf, A. ; Dachwald, B. ; Gill, E.},
  series = {IEEE Congress on Evolutionary Computation, 2009. CEC '09.},
  journal   = {IEEE Congress on Evolutionary Computation, 2009. CEC '09.},
  isbn      = {978-1-4244-2958-5},
  pages     = {358 -- 364},
  year      = {2009},
  language  = {en}
}
@article{TranKreissigStaat2009,
  author    = {Tran, Thanh Ngoc and Kreißig, R. and Staat, Manfred},
  title     = {Probabilistic limit and shakedown analysis of thin plates and shells},
  series = {Structural safety. 31 (2009), H. 1},
  journal   = {Structural safety. 31 (2009), H. 1},
  publisher = {-},
  isbn      = {0167-4730},
  pages     = {1 -- 18},
  year      = {2009},
  language  = {en}
}
@article{BassamHeschelerTemizArtmannetal.2012,
  author    = {Bassam, Rasha and Hescheler, J{\"u}rgen and Temiz Artmann, Ayseg{\"u}l and Artmann, Gerhard and Digel, Ilya},
  title     = {Effects of spermine NONOate and ATP on the thermal stability of hemoglobin},
  series = {BMC Biophysics},
  volume    = {5},
  journal   = {BMC Biophysics},
  publisher = {BioMed Central},
  address   = {London},
  issn      = {2046-1682},
  doi       = {10.1186/2046-1682-5-16},
  pages     = {Art. 16},
  year      = {2012},
  abstract  = {Background Minor changes in protein structure induced by small organic and inorganic molecules can result in significant metabolic effects. The effects can be even more profound if the molecular players are chemically active and present in the cell in considerable amounts. The aim of our study was to investigate effects of a nitric oxide donor (spermine NONOate), ATP and sodium/potassium environment on the dynamics of thermal unfolding of human hemoglobin (Hb). The effect of these molecules was examined by means of circular dichroism spectrometry (CD) in the temperature range between 25°C and 70°C. The alpha-helical content of buffered hemoglobin samples (0.1 mg/ml) was estimated via ellipticity change measurements at a heating rate of 1°C/min. Results Major results were: 1) spermine NONOate persistently decreased the hemoglobin unfolding temperature T u irrespectively of the Na + /K + environment, 2) ATP instead increased the unfolding temperature by 3°C in both sodium-based and potassium-based buffers and 3) mutual effects of ATP and NO were strongly influenced by particular buffer ionic compositions. Moreover, the presence of potassium facilitated a partial unfolding of alpha-helical structures even at room temperature. Conclusion The obtained data might shed more light on molecular mechanisms and biophysics involved in the regulation of protein activity by small solutes in the cell.},
  language  = {en}
}
@article{MansurovDigelBiisenbaevetal.2012,
  author    = {Mansurov, Z. and Digel, Ilya and Biisenbaev, M. and Savistkaya, I. and Kistaubaeva, A. and Akimbekov, Nuraly S. and Zhubanova, A.},
  title     = {Bio-composite material on the basis of carbonized rice husk in biomedicine and environmental applications},
  series = {Eurasian Chemico-Technological Journal},
  volume    = {14},
  journal   = {Eurasian Chemico-Technological Journal},
  number    = {2},
  publisher = {Institute of Combustion Problems},
  address   = {Almaty},
  issn      = {2522-4867},
  doi       = {10.18321/ectj105},
  pages     = {115 -- 131},
  year      = {2012},
  language  = {en}
}
@article{ScholzRomagnoliDachwaldetal.2011,
  author    = {Scholz, Christina and Romagnoli, Daniele and Dachwald, Bernd and Theil, Stephan},
  title     = {Performance analysis of an attitude control system for solar sails using sliding masses},
  series = {Advances in Space Research},
  volume    = {48},
  journal   = {Advances in Space Research},
  number    = {11},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0273-1177},
  pages     = {1822 -- 1835},
  year      = {2011},
  language  = {en}
}
@article{LeipoldFichtnerHeberetal.2006,
  author    = {Leipold, M. and Fichtner, H. and Heber, B. and Groepper, P. and Lascar, S. and Burger, F. and Eiden, M. and Niederstadt, T. and Sickinger, C. and Herbeck, L. and Dachwald, Bernd and Seboldt, Wolfgang},
  title     = {Heliopause Explorer - A Sailcraft Mission to the Outer Boundaries of the Solar System},
  series = {Acta Astronautica. 59 (2006), H. 8-11},
  journal   = {Acta Astronautica. 59 (2006), H. 8-11},
  isbn      = {0094-5765},
  pages     = {786 -- 796},
  year      = {2006},
  language  = {en}
}
@article{DachwaldTuryshevDittusetal.2005,
  author    = {Dachwald, Bernd and Turyshev, Slava G. and Dittus, H. and Shao, M. [u.a.]},
  title     = {Fundamental Physics with the Laser Astrometric Test Of Relativity / S.G. Turyshev ; H. Dittus ; M. Shao ... B.Dachwald ...},
  series = {Proceedings of the 39th ESLAB Symposium "Trends in Space Science and Cosmic Vision 2020" : 19 - 21 April 2005, ESTEC, Noordwijk, the Netherlands / European Space Agency. [Comp. by: F. Favata ...] . - (ESA SP ; 588)},
  journal   = {Proceedings of the 39th ESLAB Symposium "Trends in Space Science and Cosmic Vision 2020" : 19 - 21 April 2005, ESTEC, Noordwijk, the Netherlands / European Space Agency. [Comp. by: F. Favata ...] . - (ESA SP ; 588)},
  publisher = {ESA Publ. Div.},
  address   = {Noordwijk},
  isbn      = {9290928999},
  pages     = {8 -- 11},
  year      = {2005},
  language  = {en}
}
@article{DittusTuryshevDachwaldetal.2005,
  author    = {Dittus, H. and Turyshev, S. G. and Dachwald, Bernd and Blome, Hans-Joachim},
  title     = {A Mission to Explore the Pioneer Anomaly},
  series = {Proceedings of the 39th ESLAB Symposium "Trends in Space Science and Cosmic Vision 2020" : 19 - 21 April 2005, ESTEC, Noordwijk, the Netherlands / European Space Agency. [Comp. by: F. Favata ...] . - (ESA SP ; 588)},
  journal   = {Proceedings of the 39th ESLAB Symposium "Trends in Space Science and Cosmic Vision 2020" : 19 - 21 April 2005, ESTEC, Noordwijk, the Netherlands / European Space Agency. [Comp. by: F. Favata ...] . - (ESA SP ; 588)},
  publisher = {ESA Publ. Div.},
  address   = {Noordwijk},
  isbn      = {9290928999},
  pages     = {3 -- 10},
  year      = {2005},
  language  = {en}
}
@article{DachwaldMacDonaldMcInnes2007,
  author    = {Dachwald, Bernd and MacDonald, Malcolm and McInnes, Colin R.},
  title     = {Heliocentric Solar Sail Orbit Transfers with Locally Optimal Control Laws / Malcolm Macdonald ; Colin McInnes ; Bernd Dachwald},
  series = {Journal of Spacecraft and Rockets. 44 (2007), H. 1},
  journal   = {Journal of Spacecraft and Rockets. 44 (2007), H. 1},
  isbn      = {0022-4650},
  pages     = {273 -- 276},
  year      = {2007},
  language  = {en}
}
@article{DachwaldSeboldt2005,
  author    = {Dachwald, Bernd and Seboldt, Wolfgang},
  title     = {Solar Sails for Near- and Medium-Term Scientific Deep Space Missions / W. Sebolt ; B. Dachwald},
  series = {In-space propulsion : edited book of proceedings of the 10-IWCP, the 10th International Workshop on Combustion and Propulsion held in Lerici, La Spezia, Italy, 21-25 September 2003 / [ed.: Luigi T. DeLuca]},
  journal   = {In-space propulsion : edited book of proceedings of the 10-IWCP, the 10th International Workshop on Combustion and Propulsion held in Lerici, La Spezia, Italy, 21-25 September 2003 / [ed.: Luigi T. DeLuca]},
  publisher = {SP Lab, Politecnico di Milano},
  address   = {Milano},
  pages     = {getr. Z{\"a}hlung . Ill.},
  year      = {2005},
  language  = {en}
}
@article{DachwaldCarnelliVasile2006,
  author    = {Dachwald, Bernd and Carnelli, I. and Vasile, M.},
  title     = {Evolutionary Neurocontrol as a Novel Method for Low-Thrust Gravity Assist Trajectory Optimization / I. Carnelli ; B. Dachwald ; M. Vasile},
  series = {Proceedings of the Twenty-Fifth International Symposium on Space Technology and Science (Selected papers) : Kanazawa, [June 4 through June 11, 2006, at Kanazawa-shi Kanko Kaikan in Kanazawa city] / [Japan Society for Aeronautical and Space Sciences. Kohtaro Matsumoto [ed.-in-chief]},
  journal   = {Proceedings of the Twenty-Fifth International Symposium on Space Technology and Science (Selected papers) : Kanazawa, [June 4 through June 11, 2006, at Kanazawa-shi Kanko Kaikan in Kanazawa city] / [Japan Society for Aeronautical and Space Sciences. Kohtaro Matsumoto [ed.-in-chief]},
  publisher = {JSASS},
  address   = {Tokyo},
  isbn      = {4-99005-002-9},
  pages     = {569 -- 574},
  year      = {2006},
  language  = {en}
}
@article{DachwaldCarnelliVasile2006,
  author    = {Dachwald, Bernd and Carnelli, I. and Vasile, M.},
  title     = {Low-Thrust Gravity Assist Trajectory Optimization Using Evolutionary Neurocontrollers / I. Carnelli ; B. Dachwald ; M. Vasile ...},
  series = {Astrodynamics 2005 : proceedings of the AAS/AIAA astrodynamics conference held August 7 - 11, 2005, South Lake Tahoe, California / ed. by Bobby G. Williams. - Pt. 3. - (Advances in the astronautical sciences ; 123,3)},
  journal   = {Astrodynamics 2005 : proceedings of the AAS/AIAA astrodynamics conference held August 7 - 11, 2005, South Lake Tahoe, California / ed. by Bobby G. Williams. - Pt. 3. - (Advances in the astronautical sciences ; 123,3)},
  publisher = {Univelt},
  address   = {San Diego, Calif.},
  isbn      = {0-87703-527-X},
  pages     = {1911 -- 1928},
  year      = {2006},
  language  = {en}
}
@article{DachwaldLeipoldFichtner2003,
  author    = {Dachwald, Bernd and Leipold, M. and Fichtner, H.},
  title     = {Heliopause Explorer - A Sailcraft Mission to the Outer Boundaries of the Solar System / M. Leipold ; H. Fichtner ; B. Heber ... B. Dachwald ...},
  series = {Proceedings of the Fifth IAA International Conference on Low Cost Planetary Missions : 24 - 26 September 2003, ESTEC, Noordwijk, the Netherlands / [comp. by R. A. Harris]},
  journal   = {Proceedings of the Fifth IAA International Conference on Low Cost Planetary Missions : 24 - 26 September 2003, ESTEC, Noordwijk, the Netherlands / [comp. by R. A. Harris]},
  publisher = {ESA},
  address   = {Noordwijk},
  isbn      = {92-9092-853-0},
  pages     = {367 -- 375},
  year      = {2003},
  language  = {en}
}
@article{Dachwald2004,
  author    = {Dachwald, Bernd},
  title     = {Interplanetary Mission Analysis for Non-Perfectly Reflecting Solar Sailcraft Using Evolutionary Neurocontrol},
  series = {Astrodynamics 2003 : proceedings of the AAS/AIAA Astrodynamics Conference held August 3 - 7, 2003, Big Sky, Montana / ed. by Jean de Lafontaine. - Pt. 2. - (Advances in the astronautical sciences ; 116,2)},
  journal   = {Astrodynamics 2003 : proceedings of the AAS/AIAA Astrodynamics Conference held August 3 - 7, 2003, Big Sky, Montana / ed. by Jean de Lafontaine. - Pt. 2. - (Advances in the astronautical sciences ; 116,2)},
  publisher = {Univelt},
  address   = {San Diego, Calif.},
  isbn      = {0-87703-509-1},
  pages     = {1247 -- 1262},
  year      = {2004},
  language  = {en}
}
@article{DachwaldSeboldt2002,
  author    = {Dachwald, Bernd and Seboldt, Wolfgang},
  title     = {Optimization of Interplanetary Rendezvous Trajectories for Solar Sailcraft Using a Neurocontroller},
  series = {A collection of technical papers / AIAA Astrodynamics Specialist Conference : Monterey, California, 5 - 8 August 2002. - Vol. 2},
  journal   = {A collection of technical papers / AIAA Astrodynamics Specialist Conference : Monterey, California, 5 - 8 August 2002. - Vol. 2},
  publisher = {American Institute of Aeronautics and Astronautics},
  address   = {Reston, Va.},
  isbn      = {1-56347-549-9},
  pages     = {1263 -- 1270},
  year      = {2002},
  language  = {en}
}
@article{StaatTranKreissig2008,
  author    = {Staat, Manfred and Tran, Thanh Ngoc and Kreißig, R.},
  title     = {Load bearing capacity of thin shell structures made of elastoplastic material by direct methods},
  series = {Technische Mechanik. 28 (2008), H. 3-4},
  journal   = {Technische Mechanik. 28 (2008), H. 3-4},
  pages     = {299 -- 309},
  year      = {2008},
  language  = {en}
}
@article{TranPhamVuetal.2009,
  author    = {Tran, Thanh Ngoc and Pham, Phu Tinh and Vu, D. K. and Staat, Manfred},
  title     = {Reliability Analysis of Inelastic Shell Structures Under Variable Loads},
  series = {Limit States of Materials and Structures : Direct Methods / Hrsg. Dieter Weichert; Hrsg. Alan Ponter},
  journal   = {Limit States of Materials and Structures : Direct Methods / Hrsg. Dieter Weichert; Hrsg. Alan Ponter},
  publisher = {Springer Netherland},
  address   = {Berlin},
  isbn      = {978-1-4020-9633-4},
  pages     = {135 -- 156},
  year      = {2009},
  language  = {en}
}
@article{LeversStaatLaack2011,
  author    = {Levers, A. and Staat, Manfred and Laack, Walter van},
  title     = {Analyse der Langzeitwirkung der MBST® KernspinResonanzTherapie bei Gonarthrose},
  year      = {2011},
  abstract  = {Originalausgabe: Orthop{\"a}dische Praxis Jg. 47. 2011 H. 11; S. 536-543. Mit freundlicher Genehmigung des Verlags Zusammenfassung: Auf der Basis von Patientenabfragen mittels Fragebogen zum Schmerzempfinden und zur Einschr{\"a}nkung bei Aktivit{\"a}ten des allt{\"a}glichen Lebens wird die Langzeitwirkung der MBST® KernspinResonanz-Therapie bei Gonarthrose untersucht. An der Studie nahmen 39 Patienten teil, bei denen die Therapie bis zu vier Jahre zur{\"u}ckliegt. Neben einer Gesamtbetrachtung wird der Erfolg auch in Abh{\"a}ngigkeit von Alter, Geschlecht und sportlicher Aktivit{\"a}t analysiert. Insgesamt weist die Studie auf eine anhaltende Verbesserung des Gesundheitszustands mit zum Teil deutlicher Schmerzlinderung auch noch nach vier Jahren hin, jedoch mit einer leichten Schmerzzunahme gegen Ende des Untersuchungszeitraums von vier Jahren. Eine tendenziell positivere Wirkung bei Frauen, {\"a}lteren Menschen oder auch sportlich nicht-aktiven Patienten l{\"a}sst auf eine m{\"o}gliche Beeinflussung des Erfolgs der Therapie durch ({\"U}ber-)Belastung im Alltag schließen. Ein zus{\"a}tzlich positiver Effekt der Therapie auf die Knochendichte ist ebenfalls denkbar, dies bleibt jedoch offen.},
  subject      = {Kniegelenkarthrose},
  language  = {de}
}
@article{GorissenStaatLaack2012,
  author    = {Gorissen, P. and Staat, Manfred and Laack, Walter van},
  title     = {Experimentelle Kraftmessungen als Beitrag zur Wirksamkeitsbeurteilung von Schienbeinschonern im Fußballsport},
  series = {OUP Zeitschrift f{\"u}r die orthop{\"a}dische und unfallchirurgische Praxis},
  volume    = {1},
  journal   = {OUP Zeitschrift f{\"u}r die orthop{\"a}dische und unfallchirurgische Praxis},
  number    = {1},
  publisher = {Deutscher {\"A}rzte-Verlag},
  address   = {K{\"o}ln},
  issn      = {2193-5785},
  doi       = {10.3238/oup.2012.0010-0015},
  pages     = {10 -- 15},
  year      = {2012},
  abstract  = {Diese Studie besch{\"a}ftigte sich mit der D{\"a}mpfungswirkung von Schienbeinschonern, wie sie beim Fußball zum Einsatz kommen. Sie wurde mit Hilfe eines Pendelhammers durchgef{\"u}hrt, der verschiedene Aufschlagkr{\"a}fte auf die Schoner erm{\"o}glichte. Dabei wurde deutlich, dass Schienbeinschoner die beste Wirkung bei Maximalkr{\"a}ften unterhalb von 5kN erreichen k{\"o}nnen, dass bei gr{\"o}ßerer Belastung allerdings Verbesserungsbedarf besteht. Hierf{\"u}r konnte, u.a. durch den Einsatz neuer Materialien, ein guter Ansatzpunkt im „ad{\"a}quaten Zusammenspiel von Schale und Polsterung" der Schoner gefunden werden. Die Untersuchung hat weiterhin gezeigt, dass zumindest teilweise eine deutliche Verbesserung der D{\"a}mpfungswirkung der Schienbeinschoner in den letzten Jahren erreicht werden konnte.},
  subject      = {Fußball},
  language  = {de}
}
@article{HacklNacovKammerlohretal.2021,
  author    = {Hackl, Michael and Nacov, Julia and Kammerlohr, Sandra and Staat, Manfred and Buess, Eduard and Leschinger, Tim and M{\"u}ller, Lars P. and Wegmann, Kilian},
  title     = {Intratendinous Strain Variations of the Supraspinatus Tendon Depending on Repair Technique: A Biomechanical Analysis Regarding the Cause of Medial Cuff Failure},
  series = {The American Journal of Sports Medicine},
  volume    = {49},
  journal   = {The American Journal of Sports Medicine},
  number    = {7},
  publisher = {Sage},
  address   = {London},
  issn      = {1552-3365},
  doi       = {10.1177/03635465211006138},
  pages     = {1847 -- 1853},
  year      = {2021},
  language  = {en}
}
@article{StadlerEmbsDigeletal.2008,
  author    = {Stadler, Andreas M. and Embs, Jan P. and Digel, Ilya and Artmann, Gerhard and Unruh, Tobias and B{\"u}ldt, Georg and Zaccai, Guiseppe},
  title     = {Cytoplasmic water and hydration layer dynamics in human red blood cells},
  series = {Journal of the American Chemical Society. 50 (2008), H. 130},
  journal   = {Journal of the American Chemical Society. 50 (2008), H. 130},
  isbn      = {1520-5126},
  pages     = {16852 -- 16853},
  year      = {2008},
  language  = {en}
}
@article{HorbachStaatPerezVianaetal.2020,
  author    = {Horbach, Andreas and Staat, Manfred and Perez-Viana, Daniel and Simmen, Hans-Peter and Neuhaus, Valentin and Pape, Hans-Christoph and Prescher, Andreas and Ciritsis, Bernhard},
  title     = {Biomechanical in vitro examination of a standardized low-volume tubular femoroplasty},
  series = {Clinical Biomechanics},
  volume    = {80},
  journal   = {Clinical Biomechanics},
  number    = {Art. 105104},
  publisher = {Elsevier},
  address   = {Amsterdam},
  doi       = {10.1016/j.clinbiomech.2020.105104},
  year      = {2020},
  abstract  = {Background Osteoporosis is associated with the risk of fractures near the hip. Age and comorbidities increase the perioperative risk. Due to the ageing population, fracture of the proximal femur also proves to be a socio-economic problem. Preventive surgical measures have hardly been used so far. Methods 10 pairs of human femora from fresh cadavers were divided into control and low-volume femoroplasty groups and subjected to a Hayes fall-loading fracture test. The results of the respective localization and classification of the fracture site, the Singh index determined by computed tomography (CT) examination and the parameters in terms of fracture force, work to fracture and stiffness were evaluated statistically and with the finite element method. In addition, a finite element parametric study with different position angles and variants of the tubular geometry of the femoroplasty was performed. Findings Compared to the control group, the work to fracture could be increased by 33.2\%. The fracture force increased by 19.9\%. The used technique and instrumentation proved to be standardized and reproducible with an average poly(methyl methacrylate) volume of 10.5 ml. The parametric study showed the best results for the selected angle and geometry. Interpretation The cadaver studies demonstrated the biomechanical efficacy of the low-volume tubular femoroplasty. The numerical calculations confirmed the optimal choice of positioning as well as the inner and outer diameter of the tube in this setting. The standardized minimally invasive technique with the instruments developed for it could be used in further comparative studies to confirm the measured biomechanical results.},
  language  = {en}
}
@article{BassamArtmannHescheleretal.2011,
  author    = {Bassam, Rasha and Artmann, Gerhard and Hescheler, J{\"u}rgen and Graef, T. and Temiz Artmann, Ayseg{\"u}l and Porst, Dariusz and Linder, Peter and Kayser, Peter and Arinkin, Vladimir and Gossmann, Matthias and Digel, Ilya},
  title     = {Alterations in human hemoglobin structure related to red blood cell storage},
  year      = {2011},
  abstract  = {The importance of the availability of stored blood or blood cells, respectively, for urgent transfusion cannot be overestimated. Nowadays, blood storage becomes even more important since blood products are used for epidemiological studies, bio-technical research or banked for transfusion purposes. Thus blood samples must not only be processed, stored, and shipped to preserve their efficacy and safety, but also all parameters of storage must be recorded and reported for Quality Assurance. Therefore, blood banks and clinical research facilities are seeking more accurate, automated means for blood storage and blood processing.},
  subject      = {H{\"a}moglobin},
  language  = {en}
}
@article{KnoxBruggemannGossmannetal.2020,
  author    = {Knox, Ronald and Bruggemann, Andrea and Gossmann, Matthias and Thomas, Ulrich and Horv{\´a}th, Andr{\´a}s and Dragicevic, Elena and Stoelzle-Feix, Sonja and Fertig, Niels and Jung, Alexander and Raman, Aravind Hariharan and Staat, Manfred and Linder, Peter},
  title     = {Combining physiological relevance and throughput for in vitro cardiac contractility measurement},
  series = {Biophysical Journal},
  volume    = {118},
  journal   = {Biophysical Journal},
  number    = {Issue 3, Supplement 1},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0006-3495},
  doi       = {10.1016/j.bpj.2019.11.3104},
  pages     = {570a},
  year      = {2020},
  abstract  = {Despite increasing acceptance of human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) in safety pharmacology, controversy remains about the physiological relevance of existing in vitro models for their mechanical testing. We hypothesize that existing signs of immaturity of the cell models result from an improper mechanical environment. We cultured hiPSC-CMs in a 96-well format on hyperelastic silicone membranes imitating their native mechanical environment, resulting in physiological responses to compound stimuli.We validated cell responses on the FLEXcyte 96, with a set of reference compounds covering a broad range of cellular targets, including ion channel modulators, adrenergic receptor modulators and kinase inhibitors. Acute (10 - 30 min) and chronic (up to 7 days) effects were investigated. Furthermore, the measurements were complemented with electromechanical models based on electrophysiological recordings of the used cell types.hiPSC-CMs were cultured on freely-swinging, ultra-thin and hyperelastic silicone membranes. The weight of the cell culture medium deflects the membranes downwards. Rhythmic contraction of the hiPSC-CMs resulted in dynamic deflection changes which were quantified by capacitive distance sensing. The cells were cultured for 7 days prior to compound addition. Acute measurements were conducted 10-30 minutes after compound addition in standard culture medium. For chronic treatment, compound-containing medium was replaced daily for up to 7 days. Electrophysiological properties of the employed cell types were recorded by automated patch-clamp (Patchliner) and the results were integrated into the electromechanical model of the system.Calcium channel agonist S Bay K8644 and beta-adrenergic stimulator isoproterenol induced significant positive inotropic responses without additional external stimulation. Kinase inhibitors displayed cardiotoxic effects on a functional level at low concentrations. The system-integrated analysis detected alterations in beating shape as well as frequency and arrhythmic events and we provide a quantitative measure of these.},
  language  = {en}
}
@article{NguyenXuanRabczukNguyenThoietal.2011,
  author    = {Nguyen-Xuan, H. and Rabczuk, T. and Nguyen-Thoi, T. and Tran, Thanh Ngoc and Nguyen-Thanh, N.},
  title     = {Computation of limit and shakedown loads using a node-based smoothed finite element method},
  series = {International Journal for Numerical Methods in Engineering},
  volume    = {90},
  journal   = {International Journal for Numerical Methods in Engineering},
  number    = {3},
  publisher = {Wiley},
  address   = {Weinheim},
  issn      = {1097-0207},
  doi       = {10.1002/nme.3317},
  pages     = {287 -- 310},
  year      = {2011},
  abstract  = {This paper presents a novel numerical procedure for computing limit and shakedown loads of structures using a node-based smoothed FEM in combination with a primal-dual algorithm. An associated primal-dual form based on the von Mises yield criterion is adopted. The primal-dual algorithm together with a Newton-like iteration are then used to solve this associated primal-dual form to determine simultaneously both approximate upper and quasi-lower bounds of the plastic collapse limit and the shakedown limit. The present formulation uses only linear approximations and its implementation into finite element programs is quite simple. Several numerical examples are given to show the reliability, accuracy, and generality of the present formulation compared with other available methods.},
  language  = {en}
}
@article{TranStaat2021,
  author    = {Tran, Ngoc Trinh and Staat, Manfred},
  title     = {Direct plastic structural design under random strength and random load by chance constrained programming},
  series = {European Journal of Mechanics - A/Solids},
  volume    = {85},
  journal   = {European Journal of Mechanics - A/Solids},
  number    = {Article 104106},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0997-7538},
  doi       = {10.1016/j.euromechsol.2020.104106},
  year      = {2021},
  language  = {en}
}
@article{BhattaraiMayStaatetal.2022,
  author    = {Bhattarai, Aroj and May, Charlotte Anabell and Staat, Manfred and Kowalczyk, Wojciech and Tran, Thanh Ngoc},
  title     = {Layer-specific damage modeling of porcine large intestine under biaxial tension},
  series = {Bioengineering},
  volume    = {9},
  journal   = {Bioengineering},
  number    = {10, Early Access},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {2306-5354},
  doi       = {10.3390/bioengineering9100528},
  pages     = {1 -- 17},
  year      = {2022},
  abstract  = {The mechanical behavior of the large intestine beyond the ultimate stress has never been investigated. Stretching beyond the ultimate stress may drastically impair the tissue microstructure, which consequently weakens its healthy state functions of absorption, temporary storage, and transportation for defecation. Due to closely similar microstructure and function with humans, biaxial tensile experiments on the porcine large intestine have been performed in this study. In this paper, we report hyperelastic characterization of the large intestine based on experiments in 102 specimens. We also report the theoretical analysis of the experimental results, including an exponential damage evolution function. The fracture energies and the threshold stresses are set as damage material parameters for the longitudinal muscular, the circumferential muscular and the submucosal collagenous layers. A biaxial tensile simulation of a linear brick element has been performed to validate the applicability of the estimated material parameters. The model successfully simulates the biomechanical response of the large intestine under physiological and non-physiological loads.},
  language  = {en}
}
@article{KurulganDemirciLinderDemircietal.2009,
  author    = {Kurulgan Demirci, Eylem and Linder, Peter and Demirci, Taylan and Trzewik, J{\"u}rgen and Digel, Ilya and Artmann, Gerhard and Temiz Artmann, Ayseg{\"u}l},
  title     = {Contractile tension of endothelial cells: An LPS based in-vitro sepsis model},
  series = {IUBMB Life. 61 (2009), H. 3},
  journal   = {IUBMB Life. 61 (2009), H. 3},
  publisher = {Wiley},
  address   = {Weinheim},
  isbn      = {1521-6543},
  pages     = {307 -- 308},
  year      = {2009},
  language  = {en}
}
@article{PhamStaat2014,
  author    = {Pham, Phu Tinh and Staat, Manfred},
  title     = {FEM-based shakedown analysis of hardening structures},
  series = {Asia Pacific journal on computational engineering},
  journal   = {Asia Pacific journal on computational engineering},
  number    = {1},
  publisher = {SpringerOpen},
  address   = {Berlin},
  issn      = {2196-1166 (E-Journal)},
  doi       = {10.1186/2196-1166-1-4},
  pages     = {Article No. 4},
  year      = {2014},
  abstract  = {This paper develops a new finite element method (FEM)-based upper bound algorithm for limit and shakedown analysis of hardening structures by a direct plasticity method. The hardening model is a simple two-surface model of plasticity with a fixed bounding surface. The initial yield surface can translate inside the bounding surface, and it is bounded by one of the two equivalent conditions: (1) it always stays inside the bounding surface or (2) its centre cannot move outside the back-stress surface. The algorithm gives an effective tool to analyze the problems with a very high number of degree of freedom. Our numerical results are very close to the analytical solutions and numerical solutions in literature.},
  language  = {en}
}
@article{KotliarLanzl2016,
  author    = {Kotliar, Konstantin and Lanzl, I. M.},
  title     = {Mit Statistik gemeistert: perfekte Augentropfen und idealer Screeningtest : M{\"o}glichkeiten und Grenzen statistischer Methoden beim Glaukom},
  series = {Der Ophthalmologe: Zeitschrift Der Deutschen Ophthalmologischen Gesellschaft},
  journal   = {Der Ophthalmologe: Zeitschrift Der Deutschen Ophthalmologischen Gesellschaft},
  number    = {113},
  publisher = {Springer},
  address   = {Berlin},
  issn      = {0941-293X},
  doi       = {10.1007/s00347-016-0312-y},
  pages     = {838 -- 843},
  year      = {2016},
  abstract  = {Hintergrund Die Anwendung und das Verst{\"a}ndnis von Statistik sind sehr wichtig f{\"u}r die biomedizinische Forschung und f{\"u}r die klinische Praxis. Dies gilt insbesondere auch zur Absch{\"a}tzung der M{\"o}glichkeiten unterschiedlichster Diagnostik- und Therapieoptionen beim Glaukom. Die scheinbare Komplexit{\"a}t der Statistik, die zum Teil dem „gesunden Menschenverstand" zu widersprechen scheint, zusammen mit der nur vorsichtigen Akzeptanz der Statistik bei vielen Medizinern k{\"o}nnen zu bewussten und unbewussten Manipulationen bei der Datendarstellung und -interpretation f{\"u}hren. Ziel der Arbeit Ziel ist die verst{\"a}ndliche Darstellung einiger typischer Fehler in der medizinisch-statistischen Datenbehandlung. Material und Methoden Anhand hypothetischer Beispiele aus der Glaukomdiagnostik erfolgen die Darstellung der Wirkung eines hypotensiven Medikamentes sowie die Beurteilung der Ergebnisse eines diagnostischen Tests. Es werden die typischsten statistischen Einsatzbereiche und Irrtumsquellen ausf{\"u}hrlich und verst{\"a}ndlich analysiert Ergebnisse Mechanismen von Datenmanipulation und falscher Dateninterpretation werden aufgekl{\"a}rt. Typische Irrtumsquellen bei der statistischen Auswertung und Datendarstellung werden dabei erl{\"a}utert. Schlussfolgerungen Die erl{\"a}uterten praktischen Beispiele zeigen die Notwendigkeit, die Grundlagen der Statistik zu verstehen und korrekt anwenden zu k{\"o}nnen. Fehlendes Grundlagenwissen und Halbwissen der medizinischen Statistik k{\"o}nnen zu folgenschweren Missverst{\"a}ndnissen und falschen Entscheidungen in der medizinischen Forschung, aber auch in der klinischen Praxis f{\"u}hren.},
  language  = {de}
}
@article{KolditzAlbinAbeletal.2016,
  author    = {Kolditz, Melanie and Albin, Thivaharan and Abel, Dirk and Fasse, Alessandro and Br{\"u}ggemann, Gert-Peter and Albracht, Kirsten},
  title     = {Evaluation of foot position and orientation as manipulated variables to control external knee adduction moments in leg extension training},
  series = {Computer methods and programs in biomedicine},
  volume    = {171},
  journal   = {Computer methods and programs in biomedicine},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0169-2607},
  doi       = {10.1016/j.cmpb.2016.09.005},
  pages     = {81 -- 86},
  year      = {2016},
  abstract  = {Background and Objective Effective leg extension training at a leg press requires high forces, which need to be controlled to avoid training-induced damage. In order to avoid high external knee adduction moments, which are one reason for unphysiological loadings on knee joint structures, both training movements and the whole reaction force vector need to be observed. In this study, the applicability of lateral and medial changes in foot orientation and position as possible manipulated variables to control external knee adduction moments is investigated. As secondary parameters both the medio-lateral position of the center of pressure and the frontal-plane orientation of the reaction force vector are analyzed. Methods Knee adduction moments are estimated using a dynamic model of the musculoskeletal system together with the measured reaction force vector and the motion of the subject by solving the inverse kinematic and dynamic problem. Six different foot conditions with varying positions and orientations of the foot in a static leg press are evaluated and compared to a neutral foot position. Results Both lateral and medial wedges under the foot and medial and lateral shifts of the foot can influence external knee adduction moments in the presented study with six healthy subjects. Different effects are observed with the varying conditions: the pose of the leg is changed and the direction and center of pressure of the reaction force vector is influenced. Each effect results in a different direction or center of pressure of the reaction force vector. Conclusions The results allow the conclusion that foot position and orientation can be used as manipulated variables in a control loop to actively control knee adduction moments in leg extension training.},
  language  = {en}
}