@article{KirchnerOberlaenderFriedrichetal.2010,
  author    = {Kirchner, Patrick and Oberl{\"a}nder, Jan and Friedrich, Peter and Rysstad, G. and Berger, J. and Keusgen, M. and Sch{\"o}ning, Michael Josef},
  title     = {Realization of a calorimetric gas sensor on polyimide foil for applications in aseptic food industry},
  series = {Procedia Engineering. 5 (2010)},
  journal   = {Procedia Engineering. 5 (2010)},
  isbn      = {1877-7058},
  pages     = {264 -- 267},
  year      = {2010},
  language  = {en}
}
@article{MiyamotoKanekoMatsuoetal.2010,
  author    = {Miyamoto, Ko-ichiro and Kaneko, Kazumi and Matsuo, Akira and Wagner, Torsten and Kanoh, Shin`ichiro and Sch{\"o}ning, Michael Josef and Yoshinobu, Tatsuo},
  title     = {Miniaturized chemical imaging sensor system using an OLED display panel},
  series = {Procedia Engineering. 5 (2010)},
  journal   = {Procedia Engineering. 5 (2010)},
  isbn      = {1877-7058},
  pages     = {516 -- 519},
  year      = {2010},
  language  = {en}
}
@article{BohrnStuetzFleischeretal.2010,
  author    = {Bohrn, U. and St{\"u}tz, E. and Fleischer, M. and Sch{\"o}ning, Michael Josef},
  title     = {Real-time detection of CO by eukaryotic cells},
  series = {Procedia Engineering. 5 (2010)},
  journal   = {Procedia Engineering. 5 (2010)},
  isbn      = {1877-7058},
  pages     = {17 -- 20},
  year      = {2010},
  language  = {en}
}
@article{ReisertGeisslerFlorkeetal.2011,
  author    = {Reisert, Steffen and Geissler, H. and Florke, R. and Wagner, P. and Wagner, Torsten and Sch{\"o}ning, Michael Josef},
  title     = {Controlling aseptic sterilization processes by means of a multi-sensor system},
  publisher = {IEEE},
  address   = {New York},
  pages     = {18 -- 22},
  year      = {2011},
  language  = {en}
}
@article{HeidenTurekSchoening2011,
  author    = {Heiden, W. and Turek, M. and Sch{\"o}ning, Michael Josef},
  title     = {TasteIT : Analyzing chemical sensor data using fuzzy logic},
  publisher = {IEEE},
  address   = {New York},
  isbn      = {978-1-4244-9910-6},
  pages     = {1 -- 6},
  year      = {2011},
  language  = {en}
}
@article{HeidenTurekSchoening2011,
  author    = {Heiden, W. and Turek, M. and Sch{\"o}ning, Michael Josef},
  title     = {Analysis of chemical sensor data},
  series = {Proceedings of the 4th Russian-German Workshop "Innovation Information Technologies: Theory and practice" : Ufa, Russia, April 8-13, 2011 / eds. Yupsova, Nafisa ...},
  journal   = {Proceedings of the 4th Russian-German Workshop "Innovation Information Technologies: Theory and practice" : Ufa, Russia, April 8-13, 2011 / eds. Yupsova, Nafisa ...},
  publisher = {State Aviation Technical Univ.},
  address   = {Ufa},
  isbn      = {978-5-4221-0159-7},
  pages     = {76 -- 81},
  year      = {2011},
  language  = {en}
}
@inproceedings{YoshinobuMiyamotoWagneretal.2012,
  author    = {Yoshinobu, Tatsuo and Miyamoto, Ko-Ichiro and Wagner, Torsten and Sch{\"o}ning, Michael Josef},
  title     = {Miniaturized and high-speed chemical imaging systems},
  series = {Nano-Biomedical Engineering 2012. Proceedings of the Tohoku University Global Centre of Excellence Programme, Sakura Hall, Tohoku University, Sendai Japan, 5 - 6 March 2012},
  booktitle = {Nano-Biomedical Engineering 2012. Proceedings of the Tohoku University Global Centre of Excellence Programme, Sakura Hall, Tohoku University, Sendai Japan, 5 - 6 March 2012},
  editor    = {Yamaguchi, Takami},
  publisher = {World Scientific},
  address   = {Singapur},
  doi       = {10.1142/9781848169067_0045},
  pages     = {386 -- 395},
  year      = {2012},
  language  = {en}
}
@article{SpiessWilfriedAlvarezetal.2011,
  author    = {Spiess, Elmar and Wilfried, Reichardt and Alvarez, Gerardo and Gottrup, Marcus and {\"O}hlschl{\"a}ger, Peter},
  title     = {An Artificial PAP Gene Breaks Self-tolerance and Promotes Tumor Regression in the TRAMP Model for Prostate Carcinoma},
  series = {Molecular Therapy},
  volume    = {20},
  journal   = {Molecular Therapy},
  number    = {3},
  publisher = {Elsevier},
  address   = {Amsterdam},
  isbn      = {1525-0016},
  pages     = {555 -- 564},
  year      = {2011},
  language  = {en}
}
@article{GrinsvenBonStrauvenetal.2012,
  author    = {Grinsven, Bart van and Bon, Natalie vanden and Strauven, Hannelore and Grieten, Lars and Murib, Mohammed and Jim{\´e}nez Monroy, Kathia L. and Janssens, Stoffel D. and Haenen, Ken and Sch{\"o}ning, Michael Josef and Vermeeren, Veronique and Ameloot, Marcel and Michiels, Luc and Thoelen, Ronald and Ceuninck, Ward de and Wagner, Patrick},
  title     = {Heat-Transfer Resistance at Solid-Liquid Interfaces: A Tool for The Detection of Single Nucleotide Polymorphisms in DNA.},
  series = {ACS Nano},
  volume    = {6},
  journal   = {ACS Nano},
  number    = {3},
  publisher = {ACS Publications},
  address   = {Washington, DC},
  issn      = {1936-086X},
  doi       = {10.1021/nn300147e},
  pages     = {2712 -- 2721},
  year      = {2012},
  abstract  = {In this article, we report on the heat-transfer resistance at interfaces as a novel, denaturation-based method to detect single-nucleotide polymorphisms in DNA. We observed that a molecular brush of double-stranded DNA grafted onto synthetic diamond surfaces does not notably affect the heat-transfer resistance at the solid-to-liquid interface. In contrast to this, molecular brushes of single-stranded DNA cause, surprisingly, a substantially higher heat-transfer resistance and behave like a thermally insulating layer. This effect can be utilized to identify ds-DNA melting temperatures via the switching from low- to high heat-transfer resistance. The melting temperatures identified with this method for different DNA duplexes (29 base pairs without and with built-in mutations) correlate nicely with data calculated by modeling. The method is fast, label-free (without the need for fluorescent or radioactive markers), allows for repetitive measurements, and can also be extended toward array formats. Reference measurements by confocal fluorescence microscopy and impedance spectroscopy confirm that the switching of heat-transfer resistance upon denaturation is indeed related to the thermal on-chip denaturation of DNA.},
  language  = {en}
}
@article{AridaAlhaddadSchoening2011,
  author    = {Arida, Hassan A. and Al-haddad, Ameera and Sch{\"o}ning, Michael Josef},
  title     = {New Solid-State Organic Membrane Based Lead-Selective Micro-Electrode},
  series = {International Journal of Electrochemical Science. 6 (2011), H. 9},
  journal   = {International Journal of Electrochemical Science. 6 (2011), H. 9},
  isbn      = {1452-3981},
  pages     = {3858 -- 3867},
  year      = {2011},
  language  = {en}
}
@article{WernerTakenagaTakietal.2013,
  author    = {Werner, Frederik and Takenaga, Shoko and Taki, Hidenori and Sawada, Kazuaki and Sch{\"o}ning, Michael Josef},
  title     = {Comparison of label-free ACh-imaging sensors based on CCD and LAPS},
  series = {Sensors and Actuators B: Chemical (2012)},
  volume    = {177},
  journal   = {Sensors and Actuators B: Chemical (2012)},
  publisher = {Elsevier},
  address   = {Amsterdam},
  isbn      = {0925-4005},
  pages     = {745 -- 752},
  year      = {2013},
  abstract  = {Semiconductor-based chemical imaging sensors, like the light-addressable potentiometric sensor (LAPS) or the pH-imaging sensor based on a charge-coupled device (CCD), are becoming a powerful tool for label-free imaging of biological phenomena. We have proposed a polyion-based enzymatic membrane to develop an acetylcholine (ACh) imaging sensor for neural cell-activity observations. In this study, a CCD-type ACh-imaging sensor and a LAPS-type ACh-imaging sensor were fabricated and the prospect of both sensors was clarified by making a comparison of their basic characteristics.},
  language  = {en}
}
@article{KirchnerOberlaenderSucoetal.2013,
  author    = {Kirchner, Patrick and Oberl{\"a}nder, Jan and Suco, Henri-Pierre and Rysstad, Gunnar and Sch{\"o}ning, Michael Josef},
  title     = {Monitoring the microbicidal effectiveness of gaseous hydrogen peroxide in sterilisation processes by means of a calorimetric gas sensor},
  series = {Food control},
  volume    = {31},
  journal   = {Food control},
  number    = {2},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0956-7135},
  doi       = {10.1016/j.foodcont.2012.11.048},
  pages     = {530 -- 538},
  year      = {2013},
  abstract  = {In the present work, a novel method for monitoring sterilisation processes with gaseous H2O2 in combination with heat activation by means of a specially designed calorimetric gas sensor was evaluated. Therefore, the sterilisation process was extensively studied by using test specimens inoculated with Bacillus atrophaeus spores in order to identify the most influencing process factors on its microbicidal effectiveness. Besides the contact time of the test specimens with gaseous H2O2 varied between 0.2 and 0.5 s, the present H2O2 concentration in a range from 0 to 8\% v/v (volume percent) had a strong influence on the microbicidal effectiveness, whereas the change of the vaporiser temperature, gas flow and humidity were almost negligible. Furthermore, a calorimetric H2O2 gas sensor was characterised in the sterilisation process with gaseous H2O2 in a wide range of parameter settings, wherein the measurement signal has shown a linear response against the H2O2 concentration with a sensitivity of 4.75 °C/(\% v/v). In a final step, a correlation model by matching the measurement signal of the gas sensor with the microbial inactivation kinetics was established that demonstrates its suitability as an efficient method for validating the microbicidal effectiveness of sterilisation processes with gaseous H2O2.},
  language  = {en}
}
@article{WernerWagnerYoshinobuetal.2013,
  author    = {Werner, Frederik and Wagner, Torsten and Yoshinobu, Tatsuo and Keusgen, Michael and Sch{\"o}ning, Michael Josef},
  title     = {Frequency behaviour of light-addressable potentiometric sensors},
  series = {Physica Status Solidi (A)},
  volume    = {210},
  journal   = {Physica Status Solidi (A)},
  number    = {5},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {1521-396X ; 0031-8965},
  doi       = {10.1002/pssa.201200929},
  pages     = {884 -- 891},
  year      = {2013},
  abstract  = {Light-addressable potentiometric sensors (LAPS) are semiconductor-based potentiometric sensors, with the advantage to detect the concentration of a chemical species in a liquid solution above the sensor surface in a spatially resolved manner. The addressing is achieved by a modulated and focused light source illuminating the semiconductor and generating a concentration-depending photocurrent. This work introduces a LAPS set-up that is able to monitor the electrical impedance in addition to the photocurrent. The impedance spectra of a LAPS structure, with and without illumination, as well as the frequency behaviour of the LAPS measurement are investigated. The measurements are supported by electrical equivalent circuits to explain the impedance and the LAPS-frequency behaviour. The work investigates the influence of different parameters on the frequency behaviour of the LAPS. Furthermore, the phase shift of the photocurrent, the influence of the surface potential as well as the changes of the sensor impedance will be discussed.},
  language  = {en}
}
@article{MuribGrinsvenGrietenetal.2013,
  author    = {Murib, M. S. and Grinsven, B. van and Grieten, L. and Janssens, S. D. and Vermeeren, V. and Eersels, K. and Broeders, J. and Ameloot, M. and Michiels, L. and Ceuninck, W. De and Haenen, K. and Sch{\"o}ning, Michael Josef and Wagner, Patrick},
  title     = {Electronic monitoring of chemical DNA denaturation on nanocrystalline diamond electrodes with different molarities and flow rates},
  series = {Physica Status Solidi (A). Vol. 210 (2013), iss. 5},
  journal   = {Physica Status Solidi (A). Vol. 210 (2013), iss. 5},
  publisher = {Wiley-VCH},
  address   = {Berlin},
  issn      = {0031-8965},
  pages     = {911 -- 917},
  year      = {2013},
  language  = {en}
}
@article{SchiffelsPinkenburgScheldenetal.2013,
  author    = {Schiffels, Johannes and Pinkenburg, Olaf and Schelden, Maximilian and Aboulnaga, El-Hussiny A. A. and Baumann, Marcus and Selmer, Thorsten},
  title     = {An innovative cloning platform enables large-scale production and maturation of an oxygen-tolerant [NiFe]-hydrogenase from cupriavidus necator in Escherichia coli},
  series = {PLOS one. 2013},
  journal   = {PLOS one. 2013},
  publisher = {Public Library of Science},
  address   = {San Francisco, California},
  issn      = {1932-6203},
  doi       = {10.1371/journal.pone.0068812},
  year      = {2013},
  language  = {en}
}
@article{KloockMorenoBratovetal.2006,
  author    = {Kloock, Joachim P. and Moreno, Lia and Bratov, A. and Huachupoma, S. and Xu, J. and Wagner, Torsten and Yoshinobu, T. and Ermolenko, Y. and Vlasov, Y. G. and Sch{\"o}ning, Michael Josef},
  title     = {PLD-prepared cadmium sensors based on chalcogenide glasses —ISFET, LAPS and \&\#956;ISE semiconductor structures},
  series = {Sensors and Actuators B: Chemical. 118 (2006), H. 1-2},
  journal   = {Sensors and Actuators B: Chemical. 118 (2006), H. 1-2},
  isbn      = {0925-4005},
  pages     = {149 -- 155},
  year      = {2006},
  language  = {en}
}
@article{WagnerRaoKloocketal.2006,
  author    = {Wagner, Torsten and Rao, C. and Kloock, Joachim P. and Yoshinobu, T. and Otto, R. and Keusgen, M. and Sch{\"o}ning, Michael Josef},
  title     = {"LAPS Card"—A novel chip card-based light-addressable potentiometric sensor (LAPS)},
  series = {Sensors and Actuators B: Chemical. 118 (2006), H. 1-2},
  journal   = {Sensors and Actuators B: Chemical. 118 (2006), H. 1-2},
  isbn      = {0925-4005},
  pages     = {33 -- 40},
  year      = {2006},
  language  = {en}
}
@article{AridaTurekRolkaetal.2009,
  author    = {Arida, Hassan and Turek, Monika and Rolka, David and Sch{\"o}ning, Michael Josef},
  title     = {A Novel Thin-Film Copper Array Based on an Organic/Inorganic Sensor Hybrid: Microfabrication, Potentiometric Characterization, and Flow-Injection Analysis Application},
  series = {Electroanalysis. 21 (2009), H. 10},
  journal   = {Electroanalysis. 21 (2009), H. 10},
  publisher = {Wiley},
  address   = {Weinheim},
  isbn      = {1040-0397},
  pages     = {1145 -- 1151},
  year      = {2009},
  language  = {en}
}
@article{MiyamotoKuwabaraKanohetal.2009,
  author    = {Miyamoto, K. and Kuwabara, Yohei and Kanoh, Shin'ichiro and Yoshinobu, Tatsuo and Wagner, Torsten and Sch{\"o}ning, Michael Josef},
  title     = {Chemical image scanner based on FDM-LAPS},
  series = {Sensors and Actuators B: Chemical. 137 (2009), H. 2},
  journal   = {Sensors and Actuators B: Chemical. 137 (2009), H. 2},
  publisher = {Elsevier},
  address   = {Amsterdam},
  isbn      = {0925-4005},
  pages     = {533 -- 538},
  year      = {2009},
  language  = {en}
}
@article{AridaMohsenSchoening2009,
  author    = {Arida, Hassan and Mohsen, Q. and Sch{\"o}ning, Michael Josef},
  title     = {Microfabrication, characterization and analytical application of a new thin-film silver microsensor},
  series = {Electrochimica Acta. 54 (2009), H. 13},
  journal   = {Electrochimica Acta. 54 (2009), H. 13},
  isbn      = {0013-4686},
  pages     = {3543 -- 3547},
  year      = {2009},
  language  = {en}
}
@article{MorenoiCodinachsBirkenstockGarmaetal.2009,
  author    = {Moreno i Codinachs, L. and Birkenstock, C. and Garma, T. and Zierold, R. and Bachmann, J. and Nielsch, K. and Sch{\"o}ning, Michael Josef and Fontcuberta i Morral, A.},
  title     = {A micron-sized nanoporous multifunction sensing device},
  series = {physica status solidi (a) . 206 (2009), H. 3},
  journal   = {physica status solidi (a) . 206 (2009), H. 3},
  publisher = {Wiley},
  address   = {Weinheim},
  isbn      = {1862-6319},
  pages     = {435 -- 441},
  year      = {2009},
  language  = {en}
}
@article{NaetherHenkelSchneideretal.2009,
  author    = {N{\"a}ther, Niko and Henkel, Hartmut and Schneider, Andreas and Sch{\"o}ning, Michael Josef},
  title     = {Investigation of different catalytically active and passive materials for realising a hydrogen peroxide gas sensor},
  series = {physica status solidi (a) . 206 (2009), H. 3},
  journal   = {physica status solidi (a) . 206 (2009), H. 3},
  publisher = {Wiley},
  address   = {Weinheim},
  isbn      = {1862-6319},
  pages     = {449 -- 454},
  year      = {2009},
  language  = {en}
}
@article{WagnerWernerMiyamotoetal.2010,
  author    = {Wagner, Torsten and Werner, Frederik and Miyamoto, Ko-ichiro and Ackermann, Hans-Josef and Yoshinobu, Tatsuo and Sch{\"o}ning, Michael Josef},
  title     = {FPGA-based LAPS device for the flexible design of sensing sites on functional interfaces},
  series = {Physica Status Solidi (A). 207 (2010), H. 4},
  journal   = {Physica Status Solidi (A). 207 (2010), H. 4},
  isbn      = {1862-6300},
  pages     = {844 -- 849},
  year      = {2010},
  language  = {en}
}
@article{WagnerMiyamotoWerneretal.2011,
  author    = {Wagner, Torsten and Miyamoto, K. and Werner, Frederik and Sch{\"o}ning, Michael Josef and Yoshinobu, T.},
  title     = {Flexible electrochemical imaging with "zoom-in" functionality by using a new type of light-addressable potentiometric sensor},
  publisher = {IEEE},
  address   = {New York},
  pages     = {2133 -- 2135},
  year      = {2011},
  language  = {en}
}
@article{MiyamotoWagnerSchoeningetal.2011,
  author    = {Miyamoto, K. and Wagner, Torsten and Sch{\"o}ning, Michael Josef and Yoshinobu, T.},
  title     = {Multi-well structure for cell culture on the chemical imaging sensor},
  publisher = {IEEE},
  address   = {New York},
  pages     = {2130 -- 2132},
  year      = {2011},
  language  = {en}
}
@article{SpelthahnKirsanovLeginetal.2012,
  author    = {Spelthahn, Heiko and Kirsanov, Dmitry and Legin, Andrey and Osterrath, Thomas and Schubert, J{\"u}rgen and Zander, Willi and Sch{\"o}ning, Michael Josef},
  title     = {Development of a thin-film sensor array for analytical monitoring of heavy metals in aqueous solutions},
  series = {Physica Status Solidi (a)},
  volume    = {209},
  journal   = {Physica Status Solidi (a)},
  number    = {5},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  isbn      = {1862-6319},
  doi       = {10.1002/pssa.201100733},
  pages     = {885 -- 891},
  year      = {2012},
  abstract  = {In industrial processes there is a variety of heavy metals (e.g., copper, zinc, cadmium, and lead) in use for wires, coatings, paints, alloys, batteries, etc. Since the application of these transition metals for industry is inevitable, it is a vital task to develop proper analytical techniques for their monitoring at low activity levels, especially because most of these elements are acutely toxic for biological organisms. The determination of ions in solution by means of a simple and inexpensive sensor array is, therefore, a promising task. In this work, a sensor array with heavy metal-sensitive chalcogenide glass membranes for the simultaneous detection of the four ions Ag⁺, Cu2⁺, Cd2⁺, and Pb2⁺ in solution is realized. The results of the physical characterization by means of microscopy, profilometry, Rutherford backscattering spectroscopy (RBS), and scanning electron microscopy (SEM) as well as the electrochemical characterization by means of potentiometric measurements are presented. Additionally, the possibility to expand the sensor array by polymeric sensor membranes is discussed.},
  language  = {en}
}
@article{SpelthahnSchubertSchoening2012,
  author    = {Spelthahn, Heiko and Schubert, J{\"u}rgen and Sch{\"o}ning, Michael Josef},
  title     = {D{\"u}nnschichtsensoren f{\"u}r die Schwermetallanalytik},
  series = {GIT : Labor-Fachzeitschrift},
  volume    = {56},
  journal   = {GIT : Labor-Fachzeitschrift},
  number    = {4},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {0016-3538},
  pages     = {285 -- 287},
  year      = {2012},
  abstract  = {Die Detektion von Schadstoffen repr{\"a}sentiert in der Umweltanalytik eine wichtige Aufgabenstellung. Gerade die Abwasser- bzw. Brauchwasseranalytik sowie die Prozesskontrolle haben einen hohen Stellenwert. Siliziumbasierte D{\"u}nnschichtsensoren bieten eine kosteng{\"u}nstige M{\"o}glichkeit, „online"-Messungen bzw. Vor-Ort-Messungen zeitnah durchzuf{\"u}hren. In dieser Arbeit wird ein potentiometrisches Sensorarray auf der Basis von Chalkogenidgl{\"a}sern zur Detektion von Schwermetallen in w{\"a}ssrigen Medien vorgestellt.},
  language  = {en}
}
@article{WernerGroebelKrumbeetal.2012,
  author    = {Werner, Frederik and Groebel, Simone and Krumbe, Christoph and Wagner, Torsten and Selmer, Thorsten and Yoshinobu, Tatsuo and Baumann, Marcus and Sch{\"o}ning, Michael Josef},
  title     = {Nutrient concentration-sensitive microorganism-based biosensor},
  series = {Physica Status Solidi (a)},
  volume    = {209},
  journal   = {Physica Status Solidi (a)},
  number    = {5},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {1862-6319},
  doi       = {10.1002/pssa.201100801},
  pages     = {900 -- 904},
  year      = {2012},
  language  = {en}
}
@article{KirchnerReisertPuetzetal.2012,
  author    = {Kirchner, Patrick and Reisert, Steffen and P{\"u}tz, Patrick and Keusgen, Michael and Sch{\"o}ning, Michael Josef},
  title     = {Characterisation of polymeric materials as passivation layer for calorimetric H2O2 gas sensors},
  series = {Physica Status Solidi (a)},
  volume    = {209},
  journal   = {Physica Status Solidi (a)},
  number    = {5},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {1862-6319},
  doi       = {10.1002/pssa.201100773},
  pages     = {859 -- 863},
  year      = {2012},
  abstract  = {Calorimetric gas sensors for monitoring the H₂O₂ concentration at elevated temperatures in industrial sterilisation processes have been presented in previous works. These sensors are built up in form of a differential set-up of a catalytically active and passive temperature-sensitive structure. Although, various types of catalytically active dispersions have been studied, the passivation layer has to be established and therefore, chemically as well as physically characterised. In the present work, fluorinated ethylene propylene (FEP), perfluoralkoxy (PFA) and epoxy-based SU-8 photoresist as temperature-stable polymeric materials have been investigated for sensor passivation in terms of their chemical inertness against H₂O₂, their hygroscopic properties as well as their morphology. The polymeric materials were deposited via spin-coating on the temperature-sensitive structure, wherein spin-coated FEP and PFA show slight agglomerates. However, they possess a low absorption of humidity due to their hydrophobic surface, whereas the SU-8 layer has a closed surface but shows a slightly higher absorption of water. All of them were inert against gaseous H₂O₂ during the characterisation in H₂O₂ atmosphere that demonstrates their suitability as passivation layer for calorimetric H₂O₂ gas sensors.},
  language  = {en}
}
@article{NaetherEmmerichBergeretal.2006,
  author    = {N{\"a}ther, Niko and Emmerich, R{\"u}diger and Berger, J{\"o}rg and Friedrich, Peter and Henkel, Hartmut and Schneider, Andreas and Sch{\"o}ning, Michael Josef},
  title     = {A novel gas-phase hydrogen peroxide sensor basing on a combined physical/chemical transduction mechanism},
  series = {Nanofunctional materials, nanostructures, and novel devices for biological and chemical detection : November 27 - December 1, 2006, Boston, Massachusetts, USA ; [at the 2006 MRS Fall Meeting].},
  journal   = {Nanofunctional materials, nanostructures, and novel devices for biological and chemical detection : November 27 - December 1, 2006, Boston, Massachusetts, USA ; [at the 2006 MRS Fall Meeting].},
  publisher = {Materials Research Soc.},
  address   = {Warrendale, Pa.},
  isbn      = {978-1-60423-407-7},
  pages     = {63 -- 68},
  year      = {2006},
  language  = {en}
}
@article{MorenoiCodinachsKloockSchoeningetal.2008,
  author    = {Moreno i Codinachs, Lia and Kloock, Joachim P. and Sch{\"o}ning, Michael Josef and Baldi, Antoni and Ipatov, Andrey and Bratov, Andrey and Jimenez-Jorquera, Cecilia},
  title     = {Electronic integrated multisensor tongue applied to grape juice and wine analysis},
  series = {Analyst. 133 (2008)},
  journal   = {Analyst. 133 (2008)},
  isbn      = {1364-5528},
  pages     = {1440 -- 1448},
  year      = {2008},
  language  = {en}
}
@article{KrafftFoersterHartetal.2001,
  author    = {Krafft, B. and F{\"o}rster, Arnold and Hart, A. van der and Sch{\"a}pers, T.},
  title     = {Control of Aharonov-Bohm oscillations in a AlGaAs/GaAs ring by asymmetric and symmetric gate biasing},
  series = {Physica E: Low-dimensional Systems and Nanostructures. 9 (2001), H. 4},
  journal   = {Physica E: Low-dimensional Systems and Nanostructures. 9 (2001), H. 4},
  isbn      = {1386-9477},
  pages     = {635 -- 641},
  year      = {2001},
  language  = {en}
}
@article{RosenauerOberstLitvinovetal.2000,
  author    = {Rosenauer, A. and Oberst, W. and Litvinov, D. and Gerthsen, D. and F{\"o}rster, Arnold and Schmidt, R.},
  title     = {Structural and Chemical Investigation of In-0.6Ga0.4As Stranski-Krastanow Layers Burried in GaAs by Transmission Electron Microscopy},
  series = {Physical Review B. 61 (2000), H. 12},
  journal   = {Physical Review B. 61 (2000), H. 12},
  isbn      = {1095-3795},
  pages     = {8276 -- 8288},
  year      = {2000},
  language  = {en}
}
@article{ItabashiKosakaMiyamotoetal.2013,
  author    = {Itabashi, Akinori and Kosaka, Naoki and Miyamoto, Ko-ichiro and Wagner, Torsten and Sch{\"o}ning, Michael Josef},
  title     = {High-speed chemical imaging system based on front-side-illuminated LAPS},
  series = {Sensors and actuators B: Chemical},
  volume    = {182},
  journal   = {Sensors and actuators B: Chemical},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1873-3077},
  doi       = {10.1016/j.snb.2013.03.016},
  pages     = {315 -- 321},
  year      = {2013},
  abstract  = {The chemical imaging sensor is a semiconductor-based chemical sensor that can visualize the spatial distribution of specific ions on the sensing surface. The conventional chemical imaging system based on the light-addressable potentiometric sensor (LAPS), however, required a long time to obtain a chemical image, due to the slow mechanical scan of a single light beam. For high-speed imaging, a plurality of light beams modulated at different frequencies can be employed to measure the ion concentrations simultaneously at different locations on the sensor plate by frequency division multiplex (FDM). However, the conventional measurement geometry of back-side illumination limited the bandwidth of the modulation frequency required for FDM measurement, because of the low-pass filtering characteristics of carrier diffusion in the Si substrate. In this study, a high-speed chemical imaging system based on front-side-illuminated LAPS was developed, which achieved high-speed spatiotemporal recording of pH change at a rate of 70 frames per second.},
  language  = {en}
}
@article{IkenAhlbornGerlachetal.2013,
  author    = {Iken, Heiko and Ahlborn, K. and Gerlach, F. and Vonau, W. and Zander, W. and Schubert, J. and Sch{\"o}ning, Michael Josef},
  title     = {Development of redox glasses and subsequent processing by means of pulsed laser deposition for realizing silicon-based thin-film sensors},
  series = {Electrochimica acta},
  journal   = {Electrochimica acta},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1873-3859 (E-Journal); 0013-4686 (Print)},
  pages     = {Available online 30.8.2013},
  year      = {2013},
  language  = {en}
}
@article{BandodkarMolinnusMirzaetal.2014,
  author    = {Bandodkar, Amay J. and Molinnus, Denise and Mirza, Omar and Guinovart, Tomas and Windmiller, Joshua R. and Valdes-Ramirez, Gabriela and Andrade, Francisco J. and Sch{\"o}ning, Michael Josef and Wang, Joseph},
  title     = {Epidermal tattoo potentiometric sodium sensors with wireless signal transduction for continuous non-invasive sweat monitoring},
  series = {Biosensors and bioelectronics},
  volume    = {54},
  journal   = {Biosensors and bioelectronics},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1873-4235 (E-Journal); 0956-5663 (Print)},
  doi       = {10.1016/j.bios.2013.11.039},
  pages     = {603 -- 609},
  year      = {2014},
  abstract  = {This article describes the fabrication, characterization and application of an epidermal temporary-transfer tattoo-based potentiometric sensor, coupled with a miniaturized wearable wireless transceiver, for real-time monitoring of sodium in the human perspiration. Sodium excreted during perspiration is an excellent marker for electrolyte imbalance and provides valuable information regarding an individual's physical and mental wellbeing. The realization of the new skin-worn non-invasive tattoo-like sensing device has been realized by amalgamating several state-of-the-art thick film, laser printing, solid-state potentiometry, fluidics and wireless technologies. The resulting tattoo-based potentiometric sodium sensor displays a rapid near-Nernstian response with negligible carryover effects, and good resiliency against various mechanical deformations experienced by the human epidermis. On-body testing of the tattoo sensor coupled to a wireless transceiver during exercise activity demonstrated its ability to continuously monitor sweat sodium dynamics. The real-time sweat sodium concentration was transmitted wirelessly via a body-worn transceiver from the sodium tattoo sensor to a notebook while the subjects perspired on a stationary cycle. The favorable analytical performance along with the wearable nature of the wireless transceiver makes the new epidermal potentiometric sensing system attractive for continuous monitoring the sodium dynamics in human perspiration during diverse activities relevant to the healthcare, fitness, military, healthcare and skin-care domains.},
  language  = {en}
}
@article{ReisertGeisslerFloerkeetal.2013,
  author    = {Reisert, Steffen and Geissler, Hanno and Fl{\"o}rke, Rudolf and Weiler, Christian and Wagner, Patrick and Sch{\"o}ning, Michael Josef},
  title     = {Characterisation of aseptic sterilisation processes using an electronic nose},
  series = {International journal of nanotechnology},
  volume    = {Vol. 10},
  journal   = {International journal of nanotechnology},
  number    = {No. 5-7},
  publisher = {Inderscience Enterprises},
  address   = {Gen{\`e}ve},
  issn      = {1475-7435 (Print) 7141-8151 (Online)},
  pages     = {470 -- 484},
  year      = {2013},
  language  = {en}
}
@article{MiyamotoHirayamaWagneretal.2013,
  author    = {Miyamoto, Ko-ichiro and Hirayama, Yuji and Wagner, Torsten and Sch{\"o}ning, Michael Josef and Yoshinobu, Tatsuo},
  title     = {Visualization of enzymatic reaction in a microfluidic channel using chemical imaging sensor},
  series = {Electrochimica acta},
  journal   = {Electrochimica acta},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1873-3859 (E-Journal); 0013-4686 (Print)},
  pages     = {Publ. online},
  year      = {2013},
  language  = {en}
}
@misc{IngebrandtWagnerSchoening2013,
  author    = {Ingebrandt, Sven and Wagner, Patrick and Sch{\"o}ning, Michael Josef},
  title     = {Engineering of functional interfaces / guest eds. Sven Ingebrandt ; Patrick Wagner ; Michael J. Sch{\"o}ning},
  series = {Physica Status Solidi (A)},
  volume    = {Vol. 210},
  journal   = {Physica Status Solidi (A)},
  number    = {Iss. 5},
  issn      = {1521-396X (E-Journal); 1862-6319 (E-Journal); 0031-8965 (Print); 1862-6300 (Print)},
  pages     = {845},
  year      = {2013},
  language  = {en}
}
@misc{AbdelghaniMenaaObareetal.2013,
  author    = {Abdelghani, Adnane and Menaa, Bouzid and Obare, Sherine O. and Sch{\"o}ning, Michael Josef},
  title     = {Special issue on nanoscale science and technology / guest eds.: Adnane Abdelghani, Bouzid Menaa, Sherine O. Obare, Michael J. Sch{\"o}ning},
  series = {International journal of nanotechnology},
  volume    = {Vol. 10},
  journal   = {International journal of nanotechnology},
  number    = {No. 5-7},
  issn      = {1741-8151 (E-Journal), 1475-7435 (Print)},
  pages     = {373 -- 619},
  year      = {2013},
  language  = {en}
}
@article{SabitovaEbertLenzetal.2013,
  author    = {Sabitova, A. and Ebert, Ph. and Lenz, A. and Schaafhausen, S. and Ivanova, L. and D{\"a}hne, M. and Hoffmann, A. and Dunin-Borkowski, R. E. and F{\"o}rster, Arnold and Grandidier, B. and Eisele, H.},
  title     = {Intrinsic bandgap of cleaved ZnO(112¯0) surfaces},
  series = {Applied physics letters},
  volume    = {Vol. 102},
  journal   = {Applied physics letters},
  issn      = {1077-3118 (E-Journal); 0003-6951 (Print)},
  pages     = {021608},
  year      = {2013},
  language  = {en}
}
@inproceedings{TakenagaHerreraWerneretal.2013,
  author    = {Takenaga, Shoko and Herrera, Cony F. and Werner, Frederik and Biselli, Manfred and Schnitzler, Thomas and Sch{\"o}ning, Michael Josef and {\"O}hlschl{\"a}ger, Peter and Wagner, Torsten},
  title     = {Detection of the metabolic activity of cells by differential measurements based on a single light-addressable potentiometric sensor chip},
  series = {11. Dresdner Sensor-Symposium : 9.-11.12.2013},
  booktitle = {11. Dresdner Sensor-Symposium : 9.-11.12.2013},
  organization    = {Dresdner Sensor-Symposium <11, 2013>},
  isbn      = {978-3-9813484-5-3},
  pages     = {63 -- 67},
  year      = {2013},
  language  = {en}
}
@article{HeineHerrmannSelmeretal.2014,
  author    = {Heine, A. and Herrmann, G. and Selmer, Thorsten and Terwesten, F. and Buckel, W. and Reuter, K.},
  title     = {High resolution crystal structure of clostridium propionicum β-Alanyl-CoA:Ammonia Lyase, a new member of the "Hot Dog Fold" protein superfamily},
  series = {Proteins},
  volume    = {82},
  journal   = {Proteins},
  number    = {9},
  publisher = {Wiley-Liss},
  address   = {New York},
  issn      = {1097-0134 (E-Journal); 0887-3585 (Print)},
  doi       = {10.1002/prot.24557},
  pages     = {2041 -- 2053},
  year      = {2014},
  abstract  = {Clostridium propionicum is the only organism known to ferment β-alanine, a constituent of coenzyme A (CoA) and the phosphopantetheinyl prosthetic group of holo-acyl carrier protein. The first step in the fermentation is a CoA-transfer to β-alanine. Subsequently, the resulting β-alanyl-CoA is deaminated by the enzyme β-alanyl-CoA:ammonia lyase (Acl) to reversibly form ammonia and acrylyl-CoA. We have determined the crystal structure of Acl in its apo-form at a resolution of 0.97 {\AA} as well as in complex with CoA at a resolution of 1.59 {\AA}. The structures reveal that the enyzme belongs to a superfamily of proteins exhibiting a so called "hot dog fold" which is characterized by a five-stranded antiparallel β-sheet with a long α-helix packed against it. The functional unit of all "hot dog fold" proteins is a homodimer containing two equivalent substrate binding sites which are established by the dimer interface. In the case of Acl, three functional dimers combine to a homohexamer strongly resembling the homohexamer formed by YciA-like acyl-CoA thioesterases. Here, we propose an enzymatic mechanism based on the crystal structure of the Acl·CoA complex and molecular docking. Proteins 2014; 82:2041-2053. © 2014 Wiley Periodicals, Inc.},
  language  = {en}
}
@article{TakenagaBiselliSchnitzleretal.2014,
  author    = {Takenaga, Shoko and Biselli, Manfred and Schnitzler, Thomas and {\"O}hlschl{\"a}ger, Peter and Wagner, Torsten and Sch{\"o}ning, Michael Josef},
  title     = {Toward multi-analyte bioarray sensors: LAPS-based on-chip determination of a Michaelis-Menten-like kinetics for cell culturing},
  series = {Physica status solidi A : Applications and materials science},
  volume    = {211},
  journal   = {Physica status solidi A : Applications and materials science},
  number    = {6},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {1521-396X (E); 1862-6319 (E-Journal); 0031-8965 (Print); 1862-6300 (Print)},
  doi       = {10.1002/pssa.201330464},
  pages     = {1410 -- 1415},
  year      = {2014},
  abstract  = {The metabolic activity of Chinese hamster ovary (CHO) cells was observed using a light-addressable potentiometric sensor (LAPS). The dependency toward different glucose concentrations (17-200 mM) follows a Michaelis-Menten kinetics trajectory with Kₘ = 32.8 mM, and the obtained Kₘ value in this experiment was compared with that found in literature. In addition, the pH shift induced by glucose metabolism of tumor cells transfected with the HPV-16 genome (C3 cells) was successfully observed. These results indicate the possibility to determine the tumor cells metabolism with a LAPS-based measurement device.},
  language  = {en}
}
@article{OberlaenderKirchnerBoyenetal.2014,
  author    = {Oberl{\"a}nder, Jan and Kirchner, Patrick and Boyen, Hans-Gerd and Sch{\"o}ning, Michael Josef},
  title     = {Detection of hydrogen peroxide vapor by use of manganese(IV) oxide as catalyst for calorimetric gas sensors},
  series = {Physica status solidi A: Applications and materials science},
  volume    = {211},
  journal   = {Physica status solidi A: Applications and materials science},
  number    = {6},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {1521-396X (E-Journal); 1862-6319 (E-Journal); 0031-8965 (Print); 1862-6300 (Print)},
  doi       = {10.1002/pssa.201330359},
  pages     = {1372 -- 1376},
  year      = {2014},
  abstract  = {In this work, the catalyst manganese(IV) oxide (MnO2), of calorimetric gas sensors (to monitor the sterilization agent vaporized hydrogen peroxide) has been investigated in more detail. Chemical analyses by means of X-ray-induced photoelectron spectroscopy have been performed to unravel the surface chemistry prior and after exposure to hydrogen peroxide vapor at elevated temperature, as applied in the sterilization processes of beverage cartons. The surface characterization reveals a change in oxidation states of the metal oxide catalyst after exposure to hydrogen peroxide. Additionally, a cleaning effect of the catalyst, which itself is attached to the sensor surface by means of a polymer interlayer, could be observed.},
  language  = {en}
}
@article{GuoMiyamotoWagneretal.2014,
  author    = {Guo, Yuanyuan and Miyamoto, Ko-ichiro and Wagner, Torsten and Sch{\"o}ning, Michael Josef and Yoshinobu, Tatsuo},
  title     = {Theoretical study and simulation of light-addressable potentiometric sensors},
  series = {Physica status solidi (A) : applications and materials},
  volume    = {211},
  journal   = {Physica status solidi (A) : applications and materials},
  number    = {6},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {0031-8965},
  doi       = {10.1002/pssa.201330354},
  pages     = {1467 -- 1472},
  year      = {2014},
  abstract  = {The light-addressable potentiometric sensor (LAPS) is a semiconductor-based potentiometric sensor using a light probe with an ability of detecting the concentration of biochemical species in a spatially resolved manner. As an important biomedical sensor, research has been conducted to improve its performance, for instance, to realize high-speed measurement. In this work, the idea of facilitating the device-level simulation, instead of using an equivalent-circuit model, is presented for detailed analysis and optimization of the performance of the LAPS. Both carrier distribution and photocurrent response have been simulated to provide new insight into both amplitude-mode and phase-mode operations of the LAPS. Various device parameters can be examined to effectively design and optimize the LAPS structures and setups for enhanced performance.},
  language  = {en}
}
@phdthesis{Werner2014,
  author    = {Werner, Frederik},
  title     = {Development of light-addressable potentiometric sensor systems and their applications in biotechnological environments},
  pages     = {XI, 149 S.},
  year      = {2014},
  language  = {en}
}
@article{MartinezJakobTuetal.2013,
  author    = {Martinez, Ronny and Jakob, Felix and Tu, Ran and Siegert, Petra and Maurer, Karl-Heinz and Schwaneberg, Ulrich},
  title     = {Increasing activity and thermal resistance of Bacillus gibsonii alkaline protease (BgAP) by directed evolution},
  series = {Biotechnology and bioengineering},
  volume    = {Vol. 110},
  journal   = {Biotechnology and bioengineering},
  number    = {Iss. 3},
  publisher = {Wiley},
  address   = {Weinheim},
  issn      = {1097-0290 (E-Journal); 0006-3592 (Print); 0368-1467 (Print)},
  pages     = {711 -- 720},
  year      = {2013},
  language  = {en}
}
@article{RibitschHeumannKarletal.2012,
  author    = {Ribitsch, D. and Heumann, S. and Karl, W. and Gerlach, J. and Leber, R. and Birner-Gruenberger, R. and Gruber, K. and Eiteljoerg, I. and Remler, P. and Siegert, Petra and Lange, J. and Maurer, Karl-Heinz and Berg, G. and Guebitz, G. M. and Schwab, H.},
  title     = {Extracellular serine proteases from Stenotrophomonas maltophilia: Screening, isolation and heterologous expression in E. coli},
  series = {Journal of biotechnology},
  volume    = {157},
  journal   = {Journal of biotechnology},
  number    = {1},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1873-4863 (E-Journal); 0168-1656 (Print)},
  doi       = {10.1016/j.jbiotec.2011.09.025},
  pages     = {140 -- 147},
  year      = {2012},
  abstract  = {A large strain collection comprising antagonistic bacteria was screened for novel detergent proteases. Several strains displayed protease activity on agar plates containing skim milk but were inactive in liquid media. Encapsulation of cells in alginate beads induced protease production. Stenotrophomonas maltophilia emerged as best performer under washing conditions. For identification of wash-active proteases, four extracellular serine proteases called StmPr1, StmPr2, StmPr3 and StmPr4 were cloned. StmPr2 and StmPr4 were sufficiently overexpressed in E. coli. Expression of StmPr1 and StmPr3 resulted in unprocessed, insoluble protein. Truncation of most of the C-terminal domain which has been identified by enzyme modeling succeeded in expression of soluble, active StmPr1 but failed in case of StmPr3. From laundry application tests StmPr2 turned out to be a highly wash-active protease at 45 °C. Specific activity of StmPr2 determined with suc-l-Ala-l-Ala-l-Pro-l-Phe-p-nitroanilide as the substrate was 17 ± 2 U/mg. In addition we determined the kinetic parameters and cleavage preferences of protease StmPr2.},
  language  = {en}
}
@article{RibitschKarlBirnerGruenbergeretal.2010,
  author    = {Ribitsch, D. and Karl, W. and Birner-Gruenberger, R. and Gruber, K. and Eiteljoerg, I. and Remler, P. and Wieland, S. and Siegert, Petra and Maurer, Karl-Heinz and Schwab, H.},
  title     = {C-terminal truncation of a metagenome-derived detergent protease for effective expression in E. coli},
  series = {Journal of biotechnology},
  volume    = {150},
  journal   = {Journal of biotechnology},
  number    = {3},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1873-4863 (E-Journal); 0168-1656 (Print)},
  doi       = {10.1016/j.jbiotec.2010.09.947},
  pages     = {408 -- 416},
  year      = {2010},
  abstract  = {Recently, a new alkaline protease named HP70 showing highest homology to extracellular serine proteases of Stenotrophomonas maltophilia and Xanthomonas campestris was found in the course of a metagenome screening for detergent proteases (Niehaus et al., submitted for publication). Attempts to efficiently express the enzyme in common expression hosts had failed. This study reports on the realization of overexpression in Escherichia coli after structural modification of HP70. Modelling of HP70 resulted in a two-domain structure, comprising the catalytic domain and a C-terminal domain which includes about 100 amino acids. On the basis of the modelled structure the enzyme was truncated by deletion of most of the C-terminal domain yielding HP70-C477. This structural modification allowed effective expression of active enzyme using E. coli BL21-Gold as the host. Specific activity of HP70-C477 determined with suc-l-Ala-l-Ala-l-Pro-l-Phe-p-nitroanilide as the substrate was 30 ± 5 U/mg compared to 8 ± 1 U/mg of the native enzyme. HP70-C477 was most active at 40 °C and pH 7-11; these conditions are prerequisite for a potential application as detergent enzyme. Determination of kinetic parameters at 40 °C and pH = 9.5 resulted in KM = 0.23 ± 0.01 mM and kcat = 167.5 ± 3.6 s⁻¹. MS-analysis of peptide fragments obtained from incubation of HP70 and HP70-C477 with insulin B indicated that the C-terminal domain influences the cleavage preferences of the enzyme. Washing experiments confirmed the high potential of HP70-C477 as detergent protease.},
  language  = {en}
}