@article{ArtmannKellerHaasetal.1991, author = {Artmann, Gerhard and Keller, U. and Haas, J. and Amort, U. and Zang, Werner and Karschies, S.}, title = {Technik und ausgew{\"a}hlte Applikationen eines Membranbioassays roter Blutzellen}, series = {Biomedizinische Technik = Biomedical engineering. 36 (1991)}, volume = {36}, journal = {Biomedizinische Technik = Biomedical engineering. 36 (1991)}, number = {S1}, isbn = {0013-5585}, pages = {450 -- 451}, year = {1991}, language = {de} } @article{ArtmannLi1994, author = {Artmann, Gerhard and Li, Anlan}, title = {Dihydroergocryptine maintains erythrocyte fluidity in acidotic and hyperosmolar suspensions modelling hypoxic and ischemic microcirculation. Li, Anlan; Artmann, Gerhard Michael}, series = {Clinical Hemorheology. 15 (1994), H. 2}, journal = {Clinical Hemorheology. 15 (1994), H. 2}, isbn = {0271-5198}, pages = {133 -- 146}, year = {1994}, language = {en} } @article{ArtmannLiSeipeltetal.1999, author = {Artmann, Gerhard and Li, Anlan and Seipelt, H. and M{\"u}ller, C. [u.a.]}, title = {Effects of salicylic acid derivatives on red blood cell membranes. Li, Anlan; Seipelt, H.; M{\"u}ller, C.;Shi, Yong de; Artmann, Gerhard Michael}, series = {Pharmacology and Toxicology. 85 (1999)}, journal = {Pharmacology and Toxicology. 85 (1999)}, isbn = {0902-9938}, pages = {206 -- 211}, year = {1999}, language = {en} } @article{ArtmannLiZiemeretal.1996, author = {Artmann, Gerhard and Li, Anlan and Ziemer, J. and Schneider, G. [u.a.]}, title = {A photometric method to analyze induced erythrocyte shape changes. Artmann, Gerhard Michael; Li, Anlan; Ziemer, J.; Schneider, G.; Sahm, U.: ; Ziemer, J.; Schneider, G.; Sahm, U.}, series = {Biorheology. 33 (1996), H. 3}, journal = {Biorheology. 33 (1996), H. 3}, isbn = {0006-355x}, pages = {251 -- 265}, year = {1996}, language = {en} } @misc{ArtmannLinderBayeretal.2017, author = {Artmann, Gerhard and Linder, Peter and Bayer, Robin and Gossmann, Matthias}, title = {Celldrum electrode arrangement for measuring mechanical stress [Patent of invention]}, publisher = {WIPO}, address = {Geneva}, pages = {18 Seiten}, year = {2017}, abstract = {The invention pertains to a CellDrum electrode arrangement for measuring mechanical stress, comprising a mechanical holder (1 ) and a non-conductive membrane (4), whereby the membrane (4) is at least partially fixed at its circumference to the mechanical holder (1), keeping it in place when the membrane (4) may bend due to forces acting on the membrane (4), the mechanical holder (1) and the membrane (4) forming a container, whereby the membrane (1) within the container comprises an cell- membrane compound layer or biological material (3) adhered to the deformable membrane 4 which in response to stimulation by an agent may exert mechanical stress to the membrane (4) such that the membrane bending stage changes whereby the container may be filled with an electrolyte, whereby an electric contact (2) is arranged allowing to contact said electrolyte when filled into to the container, whereby within a predefined geometry to the fixing of the membrane (4) an electrode (7) is arranged, whereby the electrode (7) is electrically insulated with respect to the electric contact (2) as well as said electrolyte, whereby mechanical stress due to an agent may be measured as a change in capacitance.}, language = {en} } @incollection{ArtmannMeruvuKizildagetal.2018, author = {Artmann, Gerhard and Meruvu, Haritha and Kizildag, Sefa and Temiz Artmann, Ayseg{\"u}l}, title = {Functional Toxicology and Pharmacology Test of Cell Induced Mechanical Tensile Stress in 2D and 3D Tissue Cultures}, series = {Biological, Physical and Technical Basics of Cell Engineering}, booktitle = {Biological, Physical and Technical Basics of Cell Engineering}, editor = {Artmann, Gerhard and Temiz Artmann, Ayseg{\"u}l and Zhubanova, Azhar A. and Digel, Ilya}, publisher = {Springer}, address = {Singapore}, isbn = {978-981-10-7904-7}, doi = {10.1007/978-981-10-7904-7_7}, pages = {157 -- 192}, year = {2018}, abstract = {Mechanical forces/tensile stresses are critical determinants of cellular growth, differentiation and migration patterns in health and disease. The innovative "CellDrum technology" was designed for measuring mechanical tensile stress of cultured cell monolayers/thin tissue constructs routinely. These are cultivated on very thin silicone membranes in the so-called CellDrum. The cell layers adhere firmly to the membrane and thus transmit the cell forces generated. A CellDrum consists of a cylinder which is sealed from below with a 4 μm thick, biocompatible, functionalized silicone membrane. The weight of cell culture medium bulbs the membrane out downwards. Membrane indentation is measured. When cells contract due to drug action, membrane, cells and medium are lifted upwards. The induced indentation changes allow for lateral drug induced mechanical tension quantification of the micro-tissues. With hiPS-induced (human) Cardiomyocytes (CM) the CellDrum opens new perspectives of individualized cardiac drug testing. Here, monolayers of self-beating hiPS-CMs were grown in CellDrums. Rhythmic contractions of the hiPS-cells induce membrane up-and-down deflections. The recorded cycles allow for single beat amplitude, single beat duration, integration of the single beat amplitude over the beat time and frequency analysis. Dose effects of agonists and antagonists acting on Ca2+ channels were sensitively and highly reproducibly observed. Data were consistent with published reference data as far as they were available. The combination of the CellDrum technology with hiPS-Cardiomyocytes offers a fast, facile and precise system for pharmacological and toxicological studies. It allows new preclinical basic as well as applied research in pharmacolgy and toxicology.}, language = {en} } @article{ArtmannMontanusTeitel1991, author = {Artmann, Gerhard and Montanus, M. and Teitel, P.}, title = {Die photometrische Kapillaraggregation- ein neues Verfahren zur Messung der Erythrozytenaggregation. Montanus, M.; Artmann, Gerhard Michael; Teitel, P.}, series = {Biomedizinische Technik = Biomedical engineering. 36 (1991)}, journal = {Biomedizinische Technik = Biomedical engineering. 36 (1991)}, isbn = {0013-5585}, pages = {213 -- 215}, year = {1991}, language = {de} } @article{ArtmannSchikarsky1993, author = {Artmann, Gerhard and Schikarsky, C.}, title = {Ginkgo Biloba extract (EGb 761) protects red blood cells from oxidative damage. Artmann, Gerhard Michael; Schikarsky, C.}, series = {Clinical Hemorheology. 13 (1993), H. 4}, journal = {Clinical Hemorheology. 13 (1993), H. 4}, isbn = {0271-5198}, pages = {529 -- 539}, year = {1993}, language = {en} } @article{ArtmannSchmidSchoenbein1987, author = {Artmann, Gerhard and Schmid-Sch{\"o}nbein, H.}, title = {The microscope-photometrical-monolayer-technique- a new principle for analyzing the distribution of rheological responses in pathological and experimentally modified red cell populations. Artmann, Gerhard Michael; Schmid-Sch{\"o}nbein, H.}, series = {Microcirculation, an update : proceedings of the Fourth World Congress for Microcirculation, Tokyo, Japan, July 26-30, 1987}, journal = {Microcirculation, an update : proceedings of the Fourth World Congress for Microcirculation, Tokyo, Japan, July 26-30, 1987}, publisher = {Excerpta Medica}, address = {Amsterdam [u.a.]}, isbn = {0444809511}, pages = {475 -- 477}, year = {1987}, language = {en} } @article{ArtmannSchmidSchoenbeinGrebeetal.1988, author = {Artmann, Gerhard and Schmid-Sch{\"o}nbein, H. and Grebe, R. and Teitel, P. [u.a.]}, title = {Restoration of Microsieve Filterability of Human Red Cells After Exposure to Hyperosmolarity and Lactazidosis: Effect of Vinpocetine. Schmid-Sch{\"o}nbein, H.; Grebe, R.; Teitel, P.; Artmann, Gerhard Michael, Eschweiler, H.; Schr{\"o}der, Susanne}, series = {Drug Development Research. 14 (1988), H. 3-4}, journal = {Drug Development Research. 14 (1988), H. 3-4}, isbn = {1098-2299}, pages = {205 -- 211}, year = {1988}, language = {en} } @article{ArtmannSchmidSchoenbeinSchroederetal.1988, author = {Artmann, Gerhard and Schmid-Sch{\"o}nbein, H. and Schr{\"o}der, Susanne and Grebe, R. [u.a.]}, title = {Influence of Moxaverine-HCL on Membrane Curvature and Microsieve Filterability of Red Cells after Exposure to Hyperosmolarity and Lactacidosis. Schmid-Sch{\"o}nbein, H.; Schr{\"o}der, Susanne; Grebe, R.; Artmann, Gerhard Michael, Eschweiler, H; Teitel, P.}, series = {Arzneimittelforschung. 38 (1988), H. 5}, journal = {Arzneimittelforschung. 38 (1988), H. 5}, isbn = {0004-4172}, pages = {710 -- 716}, year = {1988}, language = {en} } @article{ArtmannShiAgostietal.1998, author = {Artmann, Gerhard and Shi, Young de and Agosti, R. and Longhini, E.}, title = {A modified casson equation to characterize blood rheology for hypertension. Shi, Young de; Artmann, Gerhard Michael; Agosti, R.; Longhini, E.}, series = {Clinical Hemorheology Microcirculation. 19 (1998), H. 2}, journal = {Clinical Hemorheology Microcirculation. 19 (1998), H. 2}, isbn = {1386-0291}, pages = {115 -- 127}, year = {1998}, language = {en} } @article{ArtmannStacheKoenigsfeld2000, author = {Artmann, Gerhard and Stache, O. and K{\"o}nigsfeld, J.}, title = {Temperaturabh{\"a}ngigkeit der Pseudopodienbildung und R{\"u}ckbildung von Granulozyten / Stache, O. ; K{\"o}nigsfeld, J. ; Artmann, G. M.}, series = {Biomedizinische Technik = Biomedical Engineering. 45 (2000), H. s1}, journal = {Biomedizinische Technik = Biomedical Engineering. 45 (2000), H. s1}, isbn = {1862-278X}, pages = {450 -- 451}, year = {2000}, language = {de} } @inproceedings{ArtmannStadlerEmbsetal.2010, author = {Artmann, Gerhard and Stadler, Andreas M. and Embs, Jan P. and Zaccai, Giuseppe and B{\"u}ldt, Georg and Digel, Ilya and Temiz Artmann, Ayseg{\"u}l}, title = {The crucial role of water in a phase transition of hemoglobin at body temperature : [abstract]}, year = {2010}, abstract = {The observation of a temperature transition of hemoglobin occurring at a critical temperature close to body temperature}, subject = {H{\"a}moglobin}, language = {en} } @article{ArtmannSungHornetal.1997, author = {Artmann, Gerhard and Sung, K.-L. Paul and Horn, Thomas and Whittemore, Darren [u.a.]}, title = {Micropipette aspiration of human erythrocytes induces echinocytes via membrane phospholipid translocation. Artmann, Gerhard Michael; Sung, K.-L. Paul; Horn, Thomas; Whittemore, Darren; Norwich, Gerald; Chien, Shu}, series = {Biophysical journal. 72 (1997), H. 3}, journal = {Biophysical journal. 72 (1997), H. 3}, isbn = {1542-0086}, pages = {1434 -- 1441}, year = {1997}, language = {en} } @article{ArtmannTeitelSchmidSchoenbein1987, author = {Artmann, Gerhard and Teitel, P. and Schmid-Sch{\"o}nbein, H.}, title = {Variable rheologische Antwort der Erythrozyten auf den Einfluß von Xantinderivaten (Coffein): Experimentelle Differenzierung von "Responders" und "Nonresponders"}, series = {11. Jahrestagung der Gesellschaft f{\"u}r Mikrozirkulation}, journal = {11. Jahrestagung der Gesellschaft f{\"u}r Mikrozirkulation}, publisher = {Karger [u.a.]}, address = {Basel [u.a.]}, pages = {100 -- 105}, year = {1987}, language = {de} } @book{ArtmannTemizArtmannZhubanovaetal.2018, author = {Artmann, Gerhard and Temiz Artmann, Ayseg{\"u}l and Zhubanova, Azhar A. and Digel, Ilya}, title = {Biological, physical and technical basics of cell engineering}, editor = {Artmann, Gerhard and Temiz Artmann, Ayseg{\"u}l and Zhubanova, Azhar A. and Digel, Ilya}, publisher = {Springer}, address = {Singapore}, isbn = {978-981-10-7903-0}, pages = {xxiv, 481 Seiten ; Illustrationen, Diagramme}, year = {2018}, language = {en} } @article{ArtmannTrzewikSchmidSchoenbein2000, author = {Artmann, Gerhard and Trzewik, J. and Schmid-Sch{\"o}nbein, G. W.}, title = {Investigation on lymphatic endothelial microvalves / Trzewik, J. ; Artmann, G. M. ; Schmid-Sch{\"o}nbein, G. W.}, series = {Biomedizinische Technik = Biomedical Engineering. 45 (2000), H. s1}, journal = {Biomedizinische Technik = Biomedical Engineering. 45 (2000), H. s1}, isbn = {1862-278X}, pages = {521 -- 522}, year = {2000}, language = {en} } @article{ArtmannTrzewikAtes2002, author = {Artmann, Gerhard and Trzewik, J{\"u}rgen and Ates, M.}, title = {A novel method to quantify mechanical tension in cell monolayers. Trzewik, J{\"u}rgen; Ates, M., Artmann, Gerhard Michael}, series = {Biomedizinische Technik. 47 (2002), H. Suppl. 1. Pt. 1}, journal = {Biomedizinische Technik. 47 (2002), H. Suppl. 1. Pt. 1}, isbn = {0013-5585}, pages = {379 -- 381}, year = {2002}, language = {en} } @article{ArtmannTrzewikMallipattuetal.2001, author = {Artmann, Gerhard and Trzewik, J{\"u}rgen and Mallipattu, S. K. and Delano, F. A. [u.a.]}, title = {Evidence for a second valve system in Lymphatics: Endothelial Microvalves. Trzewik, J{\"u}rgen; Mallipattu, S. K.; Artmann, Gerhard Michael; Delano, F. A.; Schmid-Schonbein, G. W}, series = {The FASEB Journal. 15 (2001)}, journal = {The FASEB Journal. 15 (2001)}, isbn = {1530-6860}, pages = {1711 -- 1717}, year = {2001}, language = {en} } @article{ArtmannVogelZinketal.2000, author = {Artmann, Gerhard and Vogel, A. and Zink, S. and Stache, O.}, title = {Entwicklung eines automatisierten, computergesteuerten Permeabilit{\"a}tsanalysators zur Messung an Endothelzellen / Vogel, A. ; Zinke, S. ; Stache, O. ; K{\"o}nigsfeld, J. ; Artmann, G.}, series = {Biomedizinische Technik = Biomedical Engineering. 45 (2000), H. s1}, journal = {Biomedizinische Technik = Biomedical Engineering. 45 (2000), H. s1}, isbn = {1862-278X}, pages = {479 -- 480}, year = {2000}, language = {de} } @article{ArtmannWitte1991, author = {Artmann, Gerhard and Witte, Ch.}, title = {Expertensystem f{\"u}r Personal Computer zur Strukturbestimmung des Circulus Arteriosus Willisii mittels transkranieller Dopplersonografie. Witte, Ch.; Artmann, Gerhard Michael}, series = {Biomedizinische Technik = Biomedical engineering. 36 (1991)}, journal = {Biomedizinische Technik = Biomedical engineering. 36 (1991)}, isbn = {0013-5585}, pages = {228 -- 230}, year = {1991}, language = {de} } @article{ArtmannZang1990, author = {Artmann, Gerhard and Zang, Werner}, title = {Fully automatic measurement of rheologic parameters of red blood cells = Laborautomat zur Messung mechanischer Eigenschaften roter Blutzellen}, series = {Biomedizinische Technik = Biomedical engineering. 35 (1990), H. Suppl. 3}, journal = {Biomedizinische Technik = Biomedical engineering. 35 (1990), H. Suppl. 3}, isbn = {0013-5585}, pages = {94 -- 96}, year = {1990}, language = {en} } @article{ArtmannZang1990, author = {Artmann, Gerhard and Zang, Werner}, title = {Vollautomatische Messung rheologischer Parameter roter Blutzellen}, series = {Biomedizinische Technik / Biomedical Engineering}, volume = {35}, journal = {Biomedizinische Technik / Biomedical Engineering}, number = {S3}, issn = {0013-5585}, pages = {94 -- 96}, year = {1990}, language = {de} } @article{ArtmannZerlinDigel2008, author = {Artmann, Gerhard and Zerlin, Kay and Digel, Ilya}, title = {Hemoglobin Senses Body Temperature}, series = {Bioengineering in Cell and Tissue Research / Artmann, Gerhard M. ; Chien, Shu (Eds.)}, journal = {Bioengineering in Cell and Tissue Research / Artmann, Gerhard M. ; Chien, Shu (Eds.)}, publisher = {Springer}, address = {Berlin}, isbn = {978-3-540-75408-4}, pages = {415 -- 447}, year = {2008}, language = {en} } @article{ArtmannZerlinDigeletal.2007, author = {Artmann, Gerhard and Zerlin, Kay and Digel, Ilya and Stadler, Andreas M.}, title = {Physical discontinuities at body temperature in human red blood cells / Artmann, GM ; Zerlin, K ; Digel, I ; Stadler, A ; Zaccai, G ; Temiz, AA}, series = {Tissue Engineering. 13 (2007), H. 7}, journal = {Tissue Engineering. 13 (2007), H. 7}, isbn = {1076-3279}, pages = {1778 -- 1778}, year = {2007}, language = {en} } @article{ArtmannZhouStacheBuettneretal.2002, author = {Artmann, Gerhard and Zhou-Stache, J. and Buettner, R. and Mittermayer, C. [u.a.]}, title = {Inhibition of TNF-alpha induced cell death in HUVEC and Jurkat cells by protocatechuic acid. Zhou-Stache, J.; Buettner, R.; Artmann, Gerhard Michael; Mittermayer, C.; Bosserhoff, A. K.}, series = {Medical and Biological Engineering and Computing. 40 (2002), H. 6}, journal = {Medical and Biological Engineering and Computing. 40 (2002), H. 6}, isbn = {0140-0118}, pages = {698 -- 703}, year = {2002}, language = {en} } @masterthesis{AsmuthDeStefano2022, type = {Bachelor Thesis}, author = {Asmuth, Mara and De Stefano, Miriam}, title = {GummiQs Reisen}, publisher = {FH Aachen}, address = {Aachen}, school = {Fachhochschule Aachen}, pages = {71 Seiten}, year = {2022}, abstract = {Dieser Film ist ein Trailer zur Mini-Serie GummiQs Reisen, welche von den fantastischen Abenteuern der Entdeckerinnen GummiQ und Kreska Kr{\"a}henschreck erz{\"a}hlt. Gemeinsam erkunden sie auf ihrem Kahn, der Kaleidoskop?, eine lebensfrohe Ozeanwelt, die mit winzigen, einzigartigen Inseln gespickt ist. Im Gegensatz zur jungen GummiQ, die zum ersten Mal verreist, ist Kreska schon eine erfahrene Seefahrerin und wird GummiQs Kapitänin und Mentorin. Sie leitet GummiQ nicht nur durch das Meer, sondern auch durch philosophische Gefilde. Denn jede Insel birgt ein eigenes soziales Dilemma, welches das ungew{\"o}hnliche Paar immer wieder dazu herausfordert, die Welt zu hinterfragen, von der sie glaubten, sie zu kennen. Gesprochen von Marianne Graffam. Musik von Eric Michels. Geschrieben und produziert von Miriam De Stefano und Mara Asmuth.}, language = {de} } @article{AtlasBrealeyDharetal.2012, author = {Atlas, Glen and Brealey, David and Dhar, Sunil and Dikta, Gerhard and Singer, Meryvn}, title = {Additional hemodynamic measurements with an esophageal Doppler monitor: a preliminary report of compliance, force, kinetic energy, and afterload in the clinical setting}, series = {Journal of clinical monitoring and computing}, journal = {Journal of clinical monitoring and computing}, number = {26}, publisher = {Springer Nature}, address = {London}, isbn = {1573-2614}, doi = {10.1007/s10877-012-9386-5}, pages = {473 -- 482}, year = {2012}, abstract = {The esophageal Doppler monitor (EDM) is a minimally-invasive hemodynamic device which evaluates both cardiac output (CO), and fluid status, by estimating stroke volume (SV) and calculating heart rate (HR). The measurement of these parameters is based upon a continuous and accurate approximation of distal thoracic aortic blood flow. Furthermore, the peak velocity (PV) and mean acceleration (MA), of aortic blood flow at this anatomic location, are also determined by the EDM. The purpose of this preliminary report is to examine additional clinical hemodynamic calculations of: compliance (C), kinetic energy (KE), force (F), and afterload (TSVRi). These data were derived using both velocity-based measurements, provided by the EDM, as well as other contemporaneous physiologic parameters. Data were obtained from anesthetized patients undergoing surgery or who were in a critical care unit. A graphical inspection of these measurements is presented and discussed with respect to each patient's clinical situation. When normalized to each of their initial values, F and KE both consistently demonstrated more discriminative power than either PV or MA. The EDM offers additional applications for hemodynamic monitoring. Further research regarding the accuracy, utility, and limitations of these parameters is therefore indicated.}, language = {en} } @masterthesis{Atlioglu2022, type = {Bachelor Thesis}, author = {Atlioglu, Dennis}, title = {Live it up : eine digitale Plattform f{\"u}r die Live-Veranstaltungsbranche}, publisher = {FH Aachen}, address = {Aachen}, school = {Fachhochschule Aachen}, pages = {268 Seiten}, year = {2022}, abstract = {Mit der App »atmosphere« soll die Veranstaltungsbranche in die digitale Welt eingef{\"u}hrt werden. Insbesondere nach der COVID-19 Pandemie bedarf es einer Erneuerung in dem Sektor f{\"u}r Liveunterhaltung. Die Auswirkungen der Krise auf diesen Wirtschaftszweig waren enorm und auch das Publikum litt unter der Situation. Die Mission von »atmosphere« besteht darin, den Zugang zu Veranstaltungen, Konzerten, Stand-Up-Auftritten und Festivals zu vereinfachen. Hierbei werden die Bereiche der Planung und der Buchung komplett in dem Service der App abgedeckt und die digitale Teilnahme an einem Event erm{\"o}glicht. Dies bietet neue M{\"o}glichkeiten f{\"u}r die Zukunft und dient als Alternative f{\"u}r Krisen. Insgesamt soll der Service den Zugang vereinfachen, die aufwendigen Planungsschritte reduzieren und die Knackpunkte in der Nutzererfahrung digitalisieren.}, language = {de} } @article{AttarMerkKotliaretal.2019, author = {Attar, Mandana Hossein Zadeh and Merk, Hans F. and Kotliar, Konstantin and Wurpts, Gerda and R{\"o}seler, Stefani and Moll-Slodowy, Silke and Plange, Johann and Baron, Jens Malte and Balakirski, Galina}, title = {The CD63 basophil activation test as a diagnostic tool for assessing autoimmunity in patients with chronic spontaneous urticaria}, series = {European Journal of Dermatology}, volume = {29}, journal = {European Journal of Dermatology}, number = {6}, doi = {10.1684/ejd.2019.3680}, pages = {614 -- 618}, year = {2019}, language = {en} } @article{AuffrayBruyndonckxDevroedeetal.2004, author = {Auffray, E. and Bruyndonckx, P. and Devroede, O. and Fedorov, A. and Ziemons, Karl}, title = {The ClearPET project}, series = {Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment}, volume = {527}, journal = {Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment}, number = {1-2}, isbn = {0168-9002}, pages = {171 -- 174}, year = {2004}, abstract = {The Crystal Clear Collaboration has designed and is building a high-resolution small animal PET scanner. The design is based on the use of the Hamamatsu R7600-M64 multi-anode photomultiplier tube and a LSO/LuYAP phoswich matrix with one to one coupling between the crystals and the photo-detector. The complete system will have 80 PM tubes in four rings with an inner diameter of 137 mm and an axial field of view of 110 mm. The PM pulses are digitized by free-running ADCs and digital data processing determines the gamma energy, the phoswich layer and even the pulse arrival time. Single gamma interactions are recorded and coincidences are found by software. The gantry allows rotation of the detector modules around the field of view. Simulations, and measurements a 2×4 module test set-up predict a spatial resolution of 1.5 mm in the centre of the field of view and a sensitivity of 5.9\% for a point source in the centre of the field of view.}, language = {en} } @incollection{AugensteinGuerzenichKuperjansetal.2004, author = {Augenstein, Eckardt and G{\"u}rzenich, D. and Kuperjans, Isabel and Wrobel, G.}, title = {TOP-Energy : softwaregest{\"u}tzte Analyse und Optimierung industrieller Energieversorgungssysteme}, series = {Entwicklungslinien der Energietechnik 2004}, booktitle = {Entwicklungslinien der Energietechnik 2004}, edition = {CD-ROM-Ausg.}, publisher = {VDI}, address = {D{\"u}sseldorf}, year = {2004}, language = {de} } @inproceedings{AugensteinHerbergsKuperjans2006, author = {Augenstein, Eckardt and Herbergs, S. and Kuperjans, Isabel}, title = {Planung und Bewertung der Geb{\"a}udeenergieversorgung mit TOP-Energy}, series = {Heizungs- und Raumlufttechnik : 1. Fachtagung Leonberg, 31. Januar bis 1. Februar 2006. - (VDI-Berichte ; Nr. 1921)}, booktitle = {Heizungs- und Raumlufttechnik : 1. Fachtagung Leonberg, 31. Januar bis 1. Februar 2006. - (VDI-Berichte ; Nr. 1921)}, publisher = {VDI-Verl.}, address = {D{\"u}sseldorf}, isbn = {3-18-091921-3}, pages = {57 -- 60}, year = {2006}, language = {de} } @inproceedings{AugensteinHerbergsKuperjans2005, author = {Augenstein, Eckardt and Herbergs, S. and Kuperjans, Isabel}, title = {TOP-Energy : softwaregest{\"u}tzte Analyse und Optimierung industrieller Energieversorgungssysteme ; Postershow}, series = {Optimierung in der Energiewirtschaft : Tagung Stuttgart, 27. und 28. Oktober 2005. - (VDI-Berichte ; 1908)}, booktitle = {Optimierung in der Energiewirtschaft : Tagung Stuttgart, 27. und 28. Oktober 2005. - (VDI-Berichte ; 1908)}, publisher = {VDI-Verl.}, address = {D{\"u}sseldorf}, isbn = {3-18-091908-6}, pages = {279 -- 282}, year = {2005}, language = {de} } @article{AugensteinHerbergsKuperjans2006, author = {Augenstein, Eckardt and Herbergs, S. and Kuperjans, Isabel}, title = {TOP-Energy : ein Werkzeug zur Optimierung der Geb{\"a}udeenergieversorgung}, series = {KI : K{\"a}lte, Luft, Klimatechnik}, journal = {KI : K{\"a}lte, Luft, Klimatechnik}, number = {5}, issn = {1865-5432}, pages = {198 -- 201}, year = {2006}, language = {de} } @inproceedings{AugensteinHerbergsKuperjansetal.2005, author = {Augenstein, Eckardt and Herbergs, S. and Kuperjans, Isabel and Lucas, K.}, title = {Simulation of industrial energy supply systems with integrated cost optimization}, series = {Proceedings of ECOS 2005, the 18th International Conference on Efficiency, Cost, Optimization, Simulation, and Environmental Impact of Energy Systems : Trondheim, Norway, June 20 - 22, 2005. - Vol. 2}, booktitle = {Proceedings of ECOS 2005, the 18th International Conference on Efficiency, Cost, Optimization, Simulation, and Environmental Impact of Energy Systems : Trondheim, Norway, June 20 - 22, 2005. - Vol. 2}, editor = {Kjelstrup, Signe}, publisher = {Tapir Academic Press}, address = {Trondheim}, isbn = {82-519-2041-8}, pages = {627 -- 634}, year = {2005}, language = {en} } @inproceedings{AugensteinKuperjans2001, author = {Augenstein, Eckardt and Kuperjans, Isabel}, title = {Softwaregest{\"u}tzte Analyse und Konzeption betrieblicher Energieversorgungsanlagen}, series = {Fortschrittliche Energiewandlung und -anwendung : Schwerpunkt: dezentrale Energiesysteme ; Tagung Bochum, 13. und 14. M{\"a}rz 2001. - (VDI-Berichte ; 1594)}, booktitle = {Fortschrittliche Energiewandlung und -anwendung : Schwerpunkt: dezentrale Energiesysteme ; Tagung Bochum, 13. und 14. M{\"a}rz 2001. - (VDI-Berichte ; 1594)}, publisher = {VDI-Verl.}, address = {D{\"u}sseldorf}, isbn = {3-18-091594-3}, pages = {313 -- 322}, year = {2001}, language = {de} } @inproceedings{AugensteinKuperjansLucas2002, author = {Augenstein, Eckardt and Kuperjans, Isabel and Lucas, K.}, title = {EUSEBIA - Decision-Support-System for Technical, Economical and Ecological Design and Evaluation of Industrial Energy Systems}, series = {ECOS 2002 : proceedings of the 15th International Conference on Efficiency, Costs, Optimization, Simulation and Environmental Impact of Energy Systems, Berlin, Germany July 3 - 5, 2002. - Vol. 1}, booktitle = {ECOS 2002 : proceedings of the 15th International Conference on Efficiency, Costs, Optimization, Simulation and Environmental Impact of Energy Systems, Berlin, Germany July 3 - 5, 2002. - Vol. 1}, editor = {Tsatsaronis,, Georgios}, publisher = {Techn. Univ., Inst. for Energy Engineering}, address = {Berlin}, isbn = {3-00-009533-0}, pages = {446 -- 453}, year = {2002}, language = {en} } @inproceedings{AuthCzarneckiBensberg2019, author = {Auth, Gunnar and Czarnecki, Christian and Bensberg, Frank}, title = {Impact of robotic process automation on enterprise architectures}, series = {GI Edition Proceedings Band 295 INFORMATIK 2019, Workshop-Beitr{\"a}ge}, booktitle = {GI Edition Proceedings Band 295 INFORMATIK 2019, Workshop-Beitr{\"a}ge}, editor = {Draude, Claude and Lange, Martin and Sick, Bernhard and Gesellschaft f{\"u}r Informatik e.V. (GI),}, publisher = {K{\"o}llen}, address = {Bonn}, isbn = {9783885796893}, issn = {1617-5468}, doi = {10.18420/inf2019_ws05}, pages = {59 -- 65}, year = {2019}, abstract = {The initial idea of Robotic Process Automation (RPA) is the automation of business processes through the presentation layer of existing application systems. For this simple emulation of user input and output by software robots, no changes of the systems and architecture is required. However, considering strategic aspects of aligning business and technology on an enterprise level as well as the growing capabilities of RPA driven by artificial intelligence, interrelations between RPA and Enterprise Architecture (EA) become visible and pose new questions. In this paper we discuss the relationship between RPA and EA in terms of perspectives and implications. As workin- progress we focus on identifying new questions and research opportunities related to RPA and EA.}, language = {en} } @incollection{AuthCzarneckiBensbergetal.2019, author = {Auth, Gunnar and Czarnecki, Christian and Bensberg, Frank and Thor, Andreas}, title = {Digitalisierung des Forschungsprozesses aus Sicht von Forschenden - durch Serviceintegration zum pers{\"o}nlichen Forschungsinformationssystem}, series = {Hochschulen in Zeiten der Digitalisierung : Lehre, Forschung und Organisation}, booktitle = {Hochschulen in Zeiten der Digitalisierung : Lehre, Forschung und Organisation}, editor = {Barton, Thomas and M{\"u}ller, Christian and Seel, Christian}, publisher = {Springer Vieweg}, address = {Wiesbaden}, isbn = {978-3-658-26617-2 (Print)}, doi = {10.1007/978-3-658-26618-9_17}, pages = {287 -- 307}, year = {2019}, abstract = {In der Diskussion {\"u}ber die Digitalisierung der Forschung spielt die Frage nach der optimalen IT-Unterst{\"u}tzung f{\"u}r Forschende eine wichtige Rolle. Forschende k{\"o}nnen heute an ihren Hochschulen bzw. Wissenschaftseinrichtungen auf ein breites Angebot interner IT-Dienstleistungen zur{\"u}ckgreifen, das auch kooperative IT-Dienste umfasst, die von mehreren Institutionen in Zusammenarbeit bereitgestellt werden. Außerhalb der eigenen Organisation und des weiteren Verbunds hat sich im Internet zudem ein breites externes Angebot an innovativen, h{\"a}ufig kostenlos nutzbaren Onlinediensten entwickelt. Neben horizontalen Onlinediensten, die sich prinzipiell an jeden Internetnutzer richten (bspw. Dropbox, Twitter, WhatsApp), nimmt auch die Zahl von vertikalen Diensten f{\"u}r wissenschaftliche bzw. Forschungszwecke immer weiter zu (bspw. GoogleScholar, ResearchGate, figshare). F{\"u}r Forschende er{\"o}ffnen sich damit vielf{\"a}ltige neue M{\"o}glichkeiten, ihren individuellen Forschungsprozess durch digitale Werkzeuge zu verbessern. Aufgrund rechtlicher, technischer und personeller Restriktionen k{\"o}nnen jedoch interne Dienstleister bei der Identifizierung, Auswahl und Nutzung externer Onlinedienste nur wenig Unterst{\"u}tzung leisten. Aus einer serviceorientierten Perspektive stehen Forschende zunehmend vor dem Problem, wie sich heterogene IT-Dienste interner und externer Anbieter in den eigenen Forschungsprozess integrieren lassen. Als L{\"o}sungsansatz skizziert das Kapitel das Konzept eines pers{\"o}nlichen Forschungsinformationssystems nach Gesichtspunkten eines digitalen Servicesystems.}, language = {de} } @article{AyalaHarrisKleefeldetal.2023, author = {Ayala, Rafael Ceja and Harris, Isaac and Kleefeld, Andreas and Pallikarakis, Nikolaos}, title = {Analysis of the transmission eigenvalue problem with two conductivity parameters}, series = {Applicable Analysis}, journal = {Applicable Analysis}, publisher = {Taylor \& Francis}, issn = {0003-6811}, doi = {10.1080/00036811.2023.2181167}, pages = {37 Seiten}, year = {2023}, abstract = {In this paper, we provide an analytical study of the transmission eigenvalue problem with two conductivity parameters. We will assume that the underlying physical model is given by the scattering of a plane wave for an isotropic scatterer. In previous studies, this eigenvalue problem was analyzed with one conductive boundary parameter whereas we will consider the case of two parameters. We prove the existence and discreteness of the transmission eigenvalues as well as study the dependence on the physical parameters. We are able to prove monotonicity of the first transmission eigenvalue with respect to the parameters and consider the limiting procedure as the second boundary parameter vanishes. Lastly, we provide extensive numerical experiments to validate the theoretical work.}, language = {en} } @techreport{AyarFielenbachGrossetal.2003, author = {Ayar, A. and Fielenbach, C. and Groß, Rolf Fritz and Holfeld, T. and Lockemann, S. and Severin, C. and Thulfaut, Christian and Hillemacher, B.}, title = {Druckkohlenstaubverbrennung von rheinischer Braunkohle : Abschlussbericht}, pages = {119 Seiten}, year = {2003}, abstract = {Im Rahmen des Forschungsschwerpunkts 3 wurde experimentell und theoretisch die NO{sub x}-Bildung und -Reduktion bei der Druckkohlenstaubverbrennung untersucht. Der zuvor beschriebene Einfluss der Kohlemahlung auf die Flamme konnte auch anhand der NO{sub x}-Messungen an der DKSF-Anlage Aachen bestaetigt werden. Waehrend mit Braunkohle im Staubfeuerungsbetrieb noch keine eindeutige Druckabhaengigkeit nachgewiesen werden konnte, haben vom Lehrstuhl durchgefuehrte NO{sub x}-Messungen an der DKSF-Anlage Dorsten im Schmelzkammerfeuerungsbetrieb mit der Steinkohle Spitzbergen zwischen 9 und 13 bar ein Absinken der Stickoxidkonzentrationen mit steigendem Druck ergeben. Fuer die rheinische Braunkohle soll dieser Druckeinfluss in den naechsten Versuchsfahrten ausfuehrlicher untersucht werden. Es wurde anhand von numerischen Simulationen zu einer Braunkohleflamme der 6. Versuchsfahrt ein Vergleich zwischen der NO{sub x}-Modellierung im Standard-FLUENT-Code und in dem mit User Defined Subroutines der international flame research foundation (IFRF), Ijmuiden, erweiterten FLUENT-Code vorgenommen. Es zeigte sich, dass bei der Modellierung der Stickoxidbildung die unterschiedlich vorhergesagten Flammentemperaturen eine entscheidende Rolle spielen. Eine genauere Analyse der NO{sub x}-Modelle im Vergleich zu Messergebnissen ist bei einer Schmelzkammerfeuerung mit einer stabilen Flamme vorzunehmen. Es wurden zusaetzlich Messungen zur Untersuchung der Kinetik homogener Gasphasenreaktionen in Rauchgasen an einem Stahlreaktor durchgefuehrt. Dabei wurde sowohl der thermisch bedingte als auch der durch zudosierte Additive katalysierte Abbau nitroser Komponenten betrachtet. Vergleichend wurden mit einem am Lehrstuhl entwickelten Programm die Kinetik beschrieben. Hierbei wird mit einer Sensitivitaetsanalyse eine Reduzierung der detaillierten Darstellung der Reaktionskinetik erreicht, die es erlaubt, mit einem CFD-Code wie FLUENT zwei- und dreidimensionale Rechnungen zum Abbau verschiedener Rauchgaskomponenten durchzufuehren. Die Uebereinstimmung zwischen ein- und zweidimensionalen Rechnungen und den Messungen ist gut.}, language = {de} } @incollection{AydinDoerenKuepper1996, author = {Aydin, I. and D{\"o}ren, Horst-Peter and K{\"u}pper, H.}, title = {Plasma-Auftragschweißen mit Wolframschmelzkarbid-haltigen Metallpulvern und ihre Einsatzgebiete}, series = {Thermische Spritzkonferenz = Thermal Spraying Conference. Erich Lugscheider [Hrsg.] DVS-Berichte 175}, booktitle = {Thermische Spritzkonferenz = Thermal Spraying Conference. Erich Lugscheider [Hrsg.] DVS-Berichte 175}, publisher = {DVS-Verlag}, address = {D{\"u}sseldorf}, isbn = {3-87155-480-4}, pages = {137 -- 142}, year = {1996}, language = {de} } @article{AyedKustererFunkeetal.2016, author = {Ayed, Anis Haj and Kusterer, Karsten and Funke, Harald and Keinz, Jan}, title = {CFD Based Improvement of the DLN Hydrogen Micromix Combustion Technology at Increased Energy Densities}, series = {American Scientific Research Journal for Engineering, Technology, and Sciences (ASRJETS)}, volume = {26}, journal = {American Scientific Research Journal for Engineering, Technology, and Sciences (ASRJETS)}, number = {3}, publisher = {GSSRR}, issn = {2313-4402}, pages = {290 -- 303}, year = {2016}, abstract = {Combined with the use of renewable energy sources for its production, Hydrogen represents a possible alternative gas turbine fuel within future low emission power generation. Due to the large difference in the physical properties of Hydrogen compared to other fuels such as natural gas, well established gas turbine combustion systems cannot be directly applied for Dry Low NOx (DLN) Hydrogen combustion. Thus, the development of DLN combustion technologies is an essential and challenging task for the future of Hydrogen fuelled gas turbines. The DLN Micromix combustion principle for hydrogen fuel has been developed to significantly reduce NOx-emissions. This combustion principle is based on cross-flow mixing of air and gaseous hydrogen which reacts in multiple miniaturized diffusion-type flames. The major advantages of this combustion principle are the inherent safety against flash-back and the low NOx-emissions due to a very short residence time of reactants in the flame region of the micro-flames. The Micromix Combustion technology has been already proven experimentally and numerically for pure Hydrogen fuel operation at different energy density levels. The aim of the present study is to analyze the influence of different geometry parameter variations on the flame structure and the NOx emission and to identify the most relevant design parameters, aiming to provide a physical understanding of the Micromix flame sensitivity to the burner design and identify further optimization potential of this innovative combustion technology while increasing its energy density and making it mature enough for real gas turbine application. The study reveals great optimization potential of the Micromix Combustion technology with respect to the DLN characteristics and gives insight into the impact of geometry modifications on flame structure and NOx emission. This allows to further increase the energy density of the Micromix burners and to integrate this technology in industrial gas turbines.}, language = {en} } @article{AyedKustererFunkeetal.2017, author = {Ayed, Anis Haj and Kusterer, Karsten and Funke, Harald and Keinz, Jan and Bohn, D.}, title = {CFD based exploration of the dry-low-NOx hydrogen micromix combustion technology at increased energy densities}, series = {Propulsion and Power Research}, volume = {6}, journal = {Propulsion and Power Research}, number = {1}, publisher = {Elsevier}, address = {Amsterdam}, isbn = {2212-540X}, doi = {10.1016/j.jppr.2017.01.005}, pages = {15 -- 24}, year = {2017}, language = {en} } @inproceedings{AyedStrieganKustereretal.2017, author = {Ayed, Anis Haj and Striegan, Constantin J. D. and Kusterer, Karsten and Funke, Harald and Kazari, M. and Horikawa, Atsushi and Okada, Kunio}, title = {Automated design space exploration of the hydrogen fueled "Micromix" combustor technology}, pages = {1 -- 8}, year = {2017}, abstract = {Combined with the use of renewable energy sources for its production, Hydrogen represents a possible alternative gas turbine fuel for future low emission power generation. Due to its different physical properties compared to other fuels such as natural gas, well established gas turbine combustion systems cannot be directly applied for Dry Low NOx (DLN) Hydrogen combustion. This makes the development of new combustion technologies an essential and challenging task for the future of hydrogen fueled gas turbines. The newly developed and successfully tested "DLN Micromix" combustion technology offers a great potential to burn hydrogen in gas turbines at very low NOx emissions. Aiming to further develop an existing burner design in terms of increased energy density, a redesign is required in order to stabilise the flames at higher mass flows and to maintain low emission levels. For this purpose, a systematic design exploration has been carried out with the support of CFD and optimisation tools to identify the interactions of geometrical and design parameters on the combustor performance. Aerodynamic effects as well as flame and emission formation are observed and understood time- and cost-efficiently. Correlations between single geometric values, the pressure drop of the burner and NOx production have been identified as a result. This numeric methodology helps to reduce the effort of manufacturing and testing to few designs for single validation campaigns, in order to confirm the flame stability and NOx emissions in a wider operating condition field.}, language = {en} } @inproceedings{AzarDigel2019, author = {Azar, Fouad and Digel, Ilya}, title = {Utilization of fluorescence spectroscopy and neural networks in clinical analysis}, series = {3rd YRA MedTech Symposium 2019 : May 24 / 2019 / FH Aachen}, booktitle = {3rd YRA MedTech Symposium 2019 : May 24 / 2019 / FH Aachen}, editor = {Staat, Manfred and Erni, Daniel}, publisher = {Universit{\"a}t Duisburg-Essen}, address = {Duisburg}, organization = {MedTech Symposium}, isbn = {978-3-940402-22-6}, doi = {10.17185/duepublico/48750}, pages = {40 -- 41}, year = {2019}, abstract = {Fluorescence topography of human urine in combination with learning algorithms can provide a variant pattern recognition method in analytical clinical chemistry and, eventually, diagnosis.}, language = {en} } @incollection{AzatKerimkulovaMansurovetal.2020, author = {Azat, Seitkhan and Kerimkulova, Almagul R. and Mansurov, Zulkhair A. and Adekenov, Sergazy and Artmann, Gerhard}, title = {The Use of Fusicoccin as Anticancer Compound}, series = {Carbon Nanomaterials in Biomedicine and the Environment}, booktitle = {Carbon Nanomaterials in Biomedicine and the Environment}, publisher = {Jenny Stanford Publishing}, address = {New York}, isbn = {978-0-429-42864-7}, doi = {10.1201/9780429428647-8}, pages = {149 -- 172}, year = {2020}, abstract = {The problem of creation and use of sorption materials is of current interest for the practice of the modern medicine and agriculture. Practical importance is production of a biostimulant using a carbon sorbent for a significant increase in productivity, which is very relevant for the regions of Kazakhstan. It is known that a plant phytohormone—fusicoccin—in nanogram concentrations transforms cancer cells to the state of apoptosis. In this regard, there is a scientific practical interest in the development of a highly efficient method for producing fusicoccin from extract of germinated wheat seeds. According to the results of computer modeling, cleaning composite components of fusicoccin using microporous carbon adsorbents not suitable as the size of the molecule of fusicoccin more than micropores and the optimum pore size for purification of constituents of fusicoccin was determined by computer simulation.}, language = {en} } @article{BaaderBoxbergChenetal.2023, author = {Baader, Fabian and Boxberg, Marc S. and Chen, Qian and F{\"o}rstner, Roger and Kowalski, Julia and Dachwald, Bernd}, title = {Field-test performance of an ice-melting probe in a terrestrial analogue environment}, series = {Icarus}, journal = {Icarus}, number = {409}, publisher = {Elsevier}, address = {Amsterdam}, doi = {10.1016/j.icarus.2023.115852}, pages = {Artikel 115852}, year = {2023}, abstract = {Melting probes are a proven tool for the exploration of thick ice layers and clean sampling of subglacial water on Earth. Their compact size and ease of operation also make them a key technology for the future exploration of icy moons in our Solar System, most prominently Europa and Enceladus. For both mission planning and hardware engineering, metrics such as efficiency and expected performance in terms of achievable speed, power requirements, and necessary heating power have to be known. Theoretical studies aim at describing thermal losses on the one hand, while laboratory experiments and field tests allow an empirical investigation of the true performance on the other hand. To investigate the practical value of a performance model for the operational performance in extraterrestrial environments, we first contrast measured data from terrestrial field tests on temperate and polythermal glaciers with results from basic heat loss models and a melt trajectory model. For this purpose, we propose conventions for the determination of two different efficiencies that can be applied to both measured data and models. One definition of efficiency is related to the melting head only, while the other definition considers the melting probe as a whole. We also present methods to combine several sources of heat loss for probes with a circular cross-section, and to translate the geometry of probes with a non-circular cross-section to analyse them in the same way. The models were selected in a way that minimizes the need to make assumptions about unknown parameters of the probe or the ice environment. The results indicate that currently used models do not yet reliably reproduce the performance of a probe under realistic conditions. Melting velocities and efficiencies are constantly overestimated by 15 to 50 \% in the models, but qualitatively agree with the field test data. Hence, losses are observed, that are not yet covered and quantified by the available loss models. We find that the deviation increases with decreasing ice temperature. We suspect that this mismatch is mainly due to the too restrictive idealization of the probe model and the fact that the probe was not operated in an efficiency-optimized manner during the field tests. With respect to space mission engineering, we find that performance and efficiency models must be used with caution in unknown ice environments, as various ice parameters have a significant effect on the melting process. Some of these are difficult to estimate from afar.}, language = {en} }