@article{WagnerYoshinobuRaoetal.2005, author = {Wagner, Torsten and Yoshinobu, T. and Rao, C. and Otto, R. and Sch{\"o}ning, Michael Josef}, title = {„All-in-one" solid-state device based on a lightaddressable potentiometric sensor platform}, series = {Transducers '05 : the 13th International Conference on Solid-State Sensors, Actuators and Microsystems ; Seoul, Korea, [June 5 - 9, 2005] ; digest of technical papers / sponsored by Korean Sensors Society. Technical co-sponsors: IEEE Electron Devices Society}, journal = {Transducers '05 : the 13th International Conference on Solid-State Sensors, Actuators and Microsystems ; Seoul, Korea, [June 5 - 9, 2005] ; digest of technical papers / sponsored by Korean Sensors Society. Technical co-sponsors: IEEE Electron Devices Society}, publisher = {IEEE Operations Center}, address = {Piscataway, NJ}, isbn = {0-7803-83995-6}, pages = {1872 -- 1875}, year = {2005}, language = {en} } @article{WaldvogelFreylerHelmetal.2023, author = {Waldvogel, Janice and Freyler, Kathrin and Helm, Michael and Monti, Elena and St{\"a}udle, Benjamin and Gollhofer, Albert and Narici, Marco V. and Ritzmann, Ramona and Albracht, Kirsten}, title = {Changes in gravity affect neuromuscular control, biomechanics, and muscle-tendon mechanics in energy storage and dissipation tasks}, series = {Journal of Applied Physiology}, volume = {134}, journal = {Journal of Applied Physiology}, number = {1}, publisher = {American Physiological Society}, address = {Bethesda, Md.}, issn = {1522-1601 (Onlineausgabe)}, doi = {10.1152/japplphysiol.00279.2022}, pages = {190 -- 202}, year = {2023}, abstract = {This study evaluates neuromechanical control and muscle-tendon interaction during energy storage and dissipation tasks in hypergravity. During parabolic flights, while 17 subjects performed drop jumps (DJs) and drop landings (DLs), electromyography (EMG) of the lower limb muscles was combined with in vivo fascicle dynamics of the gastrocnemius medialis, two-dimensional (2D) kinematics, and kinetics to measure and analyze changes in energy management. Comparisons were made between movement modalities executed in hypergravity (1.8 G) and gravity on ground (1 G). In 1.8 G, ankle dorsiflexion, knee joint flexion, and vertical center of mass (COM) displacement are lower in DJs than in DLs; within each movement modality, joint flexion amplitudes and COM displacement demonstrate higher values in 1.8 G than in 1 G. Concomitantly, negative peak ankle joint power, vertical ground reaction forces, and leg stiffness are similar between both movement modalities (1.8 G). In DJs, EMG activity in 1.8 G is lower during the COM deceleration phase than in 1 G, thus impairing quasi-isometric fascicle behavior. In DLs, EMG activity before and during the COM deceleration phase is higher, and fascicles are stretched less in 1.8 G than in 1 G. Compared with the situation in 1 G, highly task-specific neuromuscular activity is diminished in 1.8 G, resulting in fascicle lengthening in both movement modalities. Specifically, in DJs, a high magnitude of neuromuscular activity is impaired, resulting in altered energy storage. In contrast, in DLs, linear stiffening of the system due to higher neuromuscular activity combined with lower fascicle stretch enhances the buffering function of the tendon, and thus the capacity to safely dissipate energy.}, language = {en} } @article{WaldvogelRitzmannFreyleretal.2021, author = {Waldvogel, Janice and Ritzmann, Ramona and Freyler, Kathrin and Helm, Michael and Monti, Elena and Albracht, Kirsten and St{\"a}udle, Benjamin and Gollhofer, Albert and Narici, Marco}, title = {The Anticipation of Gravity in Human Ballistic Movement}, series = {Frontiers in Physiology}, journal = {Frontiers in Physiology}, publisher = {Frontiers}, address = {Lausanne}, issn = {1664-042X}, doi = {10.3389/fphys.2021.614060}, year = {2021}, abstract = {Stretch-shortening type actions are characterized by lengthening of the pre-activated muscle-tendon unit (MTU) in the eccentric phase immediately followed by muscle shortening. Under 1 g, pre-activity before and muscle activity after ground contact, scale muscle stiffness, which is crucial for the recoil properties of the MTU in the subsequent push-off. This study aimed to examine the neuro-mechanical coupling of the stretch-shortening cycle in response to gravity levels ranging from 0.1 to 2 g. During parabolic flights, 17 subjects performed drop jumps while electromyography (EMG) of the lower limb muscles was combined with ultrasound images of the gastrocnemius medialis, 2D kinematics and kinetics to depict changes in energy management and performance. Neuro-mechanical coupling in 1 g was characterized by high magnitudes of pre-activity and eccentric muscle activity allowing an isometric muscle behavior during ground contact. EMG during pre-activity and the concentric phase systematically increased from 0.1 to 1 g. Below 1 g the EMG in the eccentric phase was diminished, leading to muscle lengthening and reduced MTU stretches. Kinetic energy at take-off and performance were decreased compared to 1 g. Above 1 g, reduced EMG in the eccentric phase was accompanied by large MTU and muscle stretch, increased joint flexion amplitudes, energy loss and reduced performance. The energy outcome function established by linear mixed model reveals that the central nervous system regulates the extensor muscles phase- and load-specifically. In conclusion, neuro-mechanical coupling appears to be optimized in 1 g. Below 1 g, the energy outcome is compromised by reduced muscle stiffness. Above 1 g, loading progressively induces muscle lengthening, thus facilitating energy dissipation.}, language = {en} } @article{WallerBraunHojdisetal.2007, author = {Waller, Mark P. and Braun, Heiko and Hojdis, Nils and B{\"u}hl, Michael}, title = {Geometries of Second-Row Transition-Metal Complexes from Density-Functional Theory}, series = {Journal of Chemical Theory and Computation}, volume = {3}, journal = {Journal of Chemical Theory and Computation}, number = {6}, issn = {1549-9626}, doi = {10.1021/ct700178y}, pages = {2234 -- 2242}, year = {2007}, language = {en} } @article{WaltherGerthsenCariusetal.1993, author = {Walther, T. and Gerthsen, D. and Carius, Reinhard and F{\"o}rster, Arnold}, title = {AlAs/GaAs Quantum well structures: Interface properties investigated by high-resolution transmission electron microscopy and photoluminescence spectroscopy / T. Walther ; D. Gerthsen ; R. Carius ; A. F{\"o}rster ...}, series = {Microscopy of semiconducting materials 1993 : proceedings of the Royal Microscopical Society Conference held at Oxford University, 5 - 8 April 1993 / ed. by A. G. Cullis ... - (Conference series / Institute of Physics ; 134)}, journal = {Microscopy of semiconducting materials 1993 : proceedings of the Royal Microscopical Society Conference held at Oxford University, 5 - 8 April 1993 / ed. by A. G. Cullis ... - (Conference series / Institute of Physics ; 134)}, publisher = {Institute of Physics}, address = {Bristol [u.a.]}, isbn = {0-7503-0290-9}, pages = {449 -- ff.}, year = {1993}, language = {en} } @article{WangKrauseBlocketal.2003, author = {Wang, J. and Krause, R. and Block, K. and Musameh, M. and Mulchandani, A. and Sch{\"o}ning, Michael Josef}, title = {Flow injection amperometric detection of OP nerve agents based on organophosphorus-hydrolase biosensor detector}, series = {Biosensors \& Bioelectronics. 18 (2003), H. 2-3}, journal = {Biosensors \& Bioelectronics. 18 (2003), H. 2-3}, isbn = {0956-5663}, pages = {255 -- 260}, year = {2003}, language = {en} } @article{WangAnikFrohberg1988, author = {Wang, Mao and Anik, Sabri and Frohberg, Martin G.}, title = {Experiments on the electrochemical determination of the sulphur activities in the system copper-silver at 1200°C}, series = {Zeitschrift f{\"u}r Metallkunde}, volume = {79}, journal = {Zeitschrift f{\"u}r Metallkunde}, number = {5}, issn = {0044-3093}, pages = {336 -- 339}, year = {1988}, language = {en} } @article{WangAnikFrohberg1987, author = {Wang, Mao and Anik, Sabri and Frohberg, Martin G.}, title = {Thermodynamics of oxygen in the lead-antimony system at 1173 K}, series = {Erzmetall : Rohstoffgewinnung, Verarbeitung, Recycling, Umwelttechnik}, volume = {40}, journal = {Erzmetall : Rohstoffgewinnung, Verarbeitung, Recycling, Umwelttechnik}, number = {6}, issn = {0044-2658}, pages = {316 -- 319}, year = {1987}, language = {en} } @article{WangDruckenmuellerElbersetal.2014, author = {Wang, Ren-Qi and Druckenm{\"u}ller, Katharina and Elbers, Gereon and Guenther, Klaus and Crou{\´e}, Jean-Philippe}, title = {Analysis of aquatic-phase natural organic matter by optimized LDI-MS method}, series = {Journal of mass spectrometry}, volume = {49}, journal = {Journal of mass spectrometry}, number = {2}, publisher = {Wiley}, address = {Bognor Regis}, issn = {1096-9888}, doi = {10.1002/jms.3321}, pages = {154 -- 160}, year = {2014}, abstract = {The composition and physiochemical properties of aquatic-phase natural organic matter (NOM) are most important problems for both environmental studies and water industry. Laser desorption/ionization (LDI) mass spectrometry facilitated successful examinations of NOM, as humic and fulvic acids in NOM are readily ionized by the nitrogen laser. In this study, hydrophobic NOMs (HPO NOMs) from river, reservoir and waste water were characterized by this technique. The effect of analytical variables like concentration, solvent composition and laser energy was investigated. The exact masses of small molecular NOM moieties in the range of 200-1200 m/z were determined in reflectron mode. In addition, spectra of post-source-decay experiments in this range showed that some compounds from different natural NOMs had the same fragmental ions. In the large mass range of 1200-15 000 Da, macromolecules and their aggregates were found in HPO NOMs from natural waters. Highly humic HPO exhibited mass peaks larger than 8000 Da. On the other hand, the waste water and reservoir water mainly had relatively smaller molecules of about 2000 Da. The LDI-MS measurements indicated that highly humic river waters were able to form large aggregates and membrane foulants, while the HPO NOMs from waste water and reservoir water were unlikely to form large aggregates. Copyright © 2014 John Wiley \& Sons, Ltd.}, language = {en} } @article{WardoyoNoorElbersetal.2020, author = {Wardoyo, Arinto Y.P. and Noor, Johan A.E. and Elbers, Gereon and Schmitz, Sandra and Flaig, Sascha T. and Budianto, Arif}, title = {Characterizing volcanic ash elements from the 2015 eruptions of bromo and raung volcanoes, Indonesia}, series = {Polish Journal of Environmental Studies}, volume = {29}, journal = {Polish Journal of Environmental Studies}, number = {2}, publisher = {HARD}, address = {Olsztyn}, issn = {2083-5906}, doi = {10.15244/pjoes/99101}, pages = {1899 -- 1907}, year = {2020}, abstract = {The volcanic eruptions of Mt. Bromo and Mt. Raung in East Java, Indonesia, in 2015 perturbed volcanic materials and affected surface-layer air quality at surrounding locations. During the episodes, the volcanic ash from the eruptions influenced visibility, traffic accidents, flight schedules, and human health. In this research, the volcanic ash particles were collected and characterized by relying on the detail of physical observation. We performed an assessment of the volcanic ash elements to characterize the volcanic ash using two different methods which are aqua regia extracts followed by MP-AES and XRF laboratory test of bulk samples. The analysis results showed that the volcanic ash was mixed of many materials, such as Al, Si, P, K, Ca, Ti, V, Cr, Mn, Fe, Ni, and others. Fe, Si, Ca, and Al were found as the major elements, while the others were the trace elements Ba, Cr, Cu, Mn, P, Mn, Ni, Zn, Sb, Sr, and V with the minor concentrations. XRF analyses showed that Fe dominated the elements of the volcanic ash. The XRF analysis showed that Fe was at 35.40\% in Bromo and 43.00\% in Raung of the detected elements in bulk material. The results of aqua regia extracts analyzed by MP-AES were 1.80\% and 1.70\% of Fe element for Bromo and Raung volcanoes, respectively.}, language = {en} } @article{WarerkarSchmitzGoettscheetal.2011, author = {Warerkar, Shashikant and Schmitz, Stefan and G{\"o}ttsche, Joachim and Hoffschmidt, Bernhard and Reißel, Martin and Tamme, Rainer}, title = {Air-Sand Heat Exchanger for High-Temperature Storage}, series = {Journal of Solar Energy Engineering. 133 (2011), H. 2}, journal = {Journal of Solar Energy Engineering. 133 (2011), H. 2}, publisher = {ASME}, address = {New York}, isbn = {0199-6231}, pages = {021010}, year = {2011}, language = {en} } @article{WarmerWagnerSchoeningetal.2015, author = {Warmer, Johannes and Wagner, Patrick and Sch{\"o}ning, Michael Josef and Kaul, Peter}, title = {Detection of triacetone triperoxide using temperature cycled metal-oxide semiconductor gas sensors}, series = {Physica status solidi (a)}, volume = {212}, journal = {Physica status solidi (a)}, number = {6}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {1862-6319}, doi = {10.1002/pssa.201431882}, pages = {1289 -- 1298}, year = {2015}, language = {en} } @article{WeberBhujuChandraetal.2004, author = {Weber, Hans-Joachim and Bhuju, S. and Chandra, S. and Mo, X.}, title = {Fabrication of biodegradable nanofibers for tubular scaffolds in regenerative medicine / Weber, H.-J. ; Bhuju, S. ; Chandra, S. ; Mo, X.}, series = {Biomedizinische Technik. 49 (2004), H. Erg.-Bd. 2, Teil 2}, journal = {Biomedizinische Technik. 49 (2004), H. Erg.-Bd. 2, Teil 2}, pages = {1016 -- 1017}, year = {2004}, language = {en} } @article{WeberHekmatZimmermannetal.2004, author = {Weber, Hans-Joachim and Hekmat, K. and Zimmermann, T. and Kampe, S.}, title = {Impact of tranexamic acid vs. aprotinin on blood loss and transfusion requirements after cardiopulmonary bypass: a prospective, randomised, double-blind trial / Hekmat, K. ; Zimmermann, T. ; Kampe, S. ; Kasper, S. M. ; Weber, H. J. ; Geissler, H. J. ; Meh}, series = {Current Medical Research and Opinion. 20 (2004), H. 1}, journal = {Current Medical Research and Opinion. 20 (2004), H. 1}, isbn = {0300-7995}, pages = {121 -- 126}, year = {2004}, language = {en} } @article{WeberLacoKunetal.2009, author = {Weber, Hans-Joachim and Laco, Filip and Kun, Ma and Ramakrishna, S.}, title = {The dose effect of human bone marrow-derived mesenchymal stem cells on epidermal development in organotypic co-culture / Laco, Filip ; Kun, Ma ; Weber, Hans Joachim ; Ramakrishna, S. ; Chan, Casey K.}, series = {Journal of Dermatological Science. 55 (2009), H. 3}, journal = {Journal of Dermatological Science. 55 (2009), H. 3}, isbn = {0923-1811}, pages = {150 -- 160}, year = {2009}, language = {en} } @article{WeberMo2004, author = {Weber, Hans-Joachim and Mo, Xiumei}, title = {Electrospinning P(LLA-CL) nanofiber: a tubular scaffold fabrication with circumferential alignment / Xiumei Mo, Hans-Joachim Weber}, series = {Contributions from 6th Austrian Polymer Meeting : Vienna, Austria, September 15 - 17, 2003 / Symposium ed.: W. H. Binder}, journal = {Contributions from 6th Austrian Polymer Meeting : Vienna, Austria, September 15 - 17, 2003 / Symposium ed.: W. H. Binder}, publisher = {Wiley-VCH}, address = {Weinheim}, pages = {413 -- 416}, year = {2004}, language = {en} } @article{WeberMoChen2007, author = {Weber, Hans-Joachim and Mo, Xiumei and Chen, Zonggang}, title = {Electrospun nanofibers of collagen-chitosan and P(LLA-CL) for tissue engineering / Mo Xiumei, Chen Zonggang, Hans J. Weber}, series = {Frontiers of materials science in China. 1 (2007), H. 1}, journal = {Frontiers of materials science in China. 1 (2007), H. 1}, publisher = {-}, isbn = {1673-7377}, pages = {20 -- 23}, year = {2007}, language = {en} } @article{WeberMoRamakrishna2006, author = {Weber, Hans-Joachim and Mo, Xiumei and Ramakrishna, S.}, title = {PCL-PGLA composite tubular scaffold preparation and biocompatibility investigation / X. Mo, H.-J. Weber, S. Ramakrishna}, series = {The International journal of artificial organs. 29 (2006), H. 8}, journal = {The International journal of artificial organs. 29 (2006), H. 8}, publisher = {-}, pages = {790 -- 799}, year = {2006}, language = {en} } @article{WeberArentMuenchetal.2016, author = {Weber, Tobias and Arent, Jan-Christoph and M{\"u}nch, Lukas and Duhovic, Miro and Balvers, Johannes M.}, title = {A fast method for the generation of boundary conditions for thermal autoclave simulation}, series = {Composites Part A}, volume = {88}, journal = {Composites Part A}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1359-835X}, doi = {10.1016/j.compositesa.2016.05.036}, pages = {216 -- 225}, year = {2016}, abstract = {Manufacturing process simulation enables the evaluation and improvement of autoclave mold concepts early in the design phase. To achieve a high part quality at low cycle times, the thermal behavior of the autoclave mold can be investigated by means of simulations. Most challenging for such a simulation is the generation of necessary boundary conditions. Heat-up and temperature distribution in an autoclave mold are governed by flow phenomena, tooling material and shape, position within the autoclave, and the chosen autoclave cycle. This paper identifies and summarizes the most important factors influencing mold heat-up and how they can be introduced into a thermal simulation. Thermal measurements are used to quantify the impact of the various parameters. Finally, the gained knowledge is applied to develop a semi-empirical approach for boundary condition estimation that enables a simple and fast thermal simulation of the autoclave curing process with reasonably high accuracy for tooling optimization.}, language = {en} } @article{WeberArentSteffenetal.2017, author = {Weber, Tobias and Arent, Jan-Christoph and Steffen, Lucas and Balvers, Johannes M. and Duhovic, Miro}, title = {Thermal optimization of composite autoclave molds using the shift factor approach for boundary condition estimation}, series = {Journal of Composite Materials}, volume = {51}, journal = {Journal of Composite Materials}, number = {12}, publisher = {Sage}, address = {London}, issn = {1530-793X}, doi = {10.1177/0021998317699868}, pages = {1753 -- 1767}, year = {2017}, language = {en} } @article{WeberEnglhardArentetal.2019, author = {Weber, Tobias and Englhard, Markus and Arent, Jan-Christoph and Hausmann, Joachim}, title = {An experimental characterization of wrinkling generated during prepreg autoclave manufacturing using caul plates}, series = {Journal of Composite Materials}, volume = {53}, journal = {Journal of Composite Materials}, number = {26-27}, issn = {1530-793X}, doi = {10.1177/0021998319846556}, pages = {3757 -- 3773}, year = {2019}, language = {en} } @article{WeberRuffStahl2017, author = {Weber, Tobias and Ruff-Stahl, Hans-Joachim K.}, title = {Advances in Composite Manufacturing of Helicopter Parts}, series = {International Journal of Aviation, Aeronautics, and Aerospace}, volume = {4}, journal = {International Journal of Aviation, Aeronautics, and Aerospace}, number = {1}, issn = {2374-6793}, doi = {10.15394/ijaaa.2017.1153}, year = {2017}, language = {en} } @article{WeckesserGriessmeierSchmidtetal.1998, author = {Weckesser, Martin and Grießmeier, Martin and Schmidt, Daniela and Sonnenberg, Frank and Ziemons, Karl and Kemna, Lars and Holschbach, Marcus and Langen, Karl-J. and M{\"u}ller-G{\"a}rtner, Hans-W.}, title = {Iodine-123 α-methyl tyrosine single-photon emission tomography of cerebral gliomas: standardised evaluation of tumour uptake and extent}, series = {European Journal of Nuclear Medicine}, volume = {25}, journal = {European Journal of Nuclear Medicine}, number = {2}, isbn = {1619-7089}, pages = {150 -- 156}, year = {1998}, abstract = {Single-photon emission tomography (SPET) with the amino acid analogue l-3-[123I]iodo-α-methyl tyrosine (IMT) is helpful in the diagnosis and monitoring of cerebral gliomas. Radiolabelled amino acids seem to reflect tumour infiltration more specifically than conventional methods like magnetic resonance imaging and computed tomography. Automatic tumour delineation based on maximal tumour uptake may cause an overestimation of mean tumour uptake and an underestimation of tumour extension in tumours with circumscribed peaks. The aim of this study was to develop a program for tumour delineation and calculation of mean tumour uptake which takes into account the mean background activity and is thus optimised to the problem of tumour definition in IMT SPET. Using the frequency distribution of pixel intensities of the tomograms a program was developed which automatically detects a reference brain region and draws an isocontour region around the tumour taking into account mean brain radioactivity. Tumour area and tumour/brain ratios were calculated. A three-compartment phantom was simulated to test the program. The program was applied to IMT SPET studies of 20 patients with cerebral gliomas and was compared to the results of manual analysis by three different investigators. Activity ratios and chamber extension of the phantom were correctly calculated by the automatic analysis. A method based on image maxima alone failed to determine chamber extension correctly. Manual region of interest analysis in patient studies resulted in a mean inter-observer standard deviation of 8.7\%±6.1\% (range 2.7\%-25.0\%). The mean value of the results of the manual analysis showed a significant correlation to the results of the automatic analysis (r = 0.91, P<0.0001 for the uptake ratio; r = 0.87, P<0.0001 for the tumour area). We conclude that the algorithm proposed simplifies the calculation of uptake ratios and may be used for observer-independent evaluation of IMT SPET studies. Three-dimensional tumour recognition and transfer to co-registered morphological images based on this program may be useful for the planning of surgical and radiation treatment.}, language = {en} } @article{WeckesserHufnagelZiemonsetal.1997, author = {Weckesser, Matthias and Hufnagel, Andreas and Ziemons, Karl and Grießmeier, Martin and Sonnenberg, Frank and Hackl{\"a}nder, Thomas and Langen, Karl-J. and Holschbach, Markus and Elger, Christian E. and M{\"u}ller-G{\"a}rtner, Hans-W.}, title = {Effect of partial volume correction on muscarinic cholinergic receptor imaging with single-photon emission tomography in patients with temporal lobe epilepsy}, series = {European Journal of Nuclear Medicine}, volume = {24}, journal = {European Journal of Nuclear Medicine}, number = {9}, isbn = {1619-7089}, pages = {1156 -- 1161}, year = {1997}, abstract = {Animal experiments and preliminary results in humans have indicated alterations of hippocampal muscarinic acetylcholine receptors (mAChR) in temporal lobe epilepsy. Patients with temporal lobe epilepsy often present with a reduction in hippocampal volume. The aim of this study was to investigate the influence of hippocampal atrophy on the quantification of mAChR with single photon emission tomography (SPET) in patients with temporal lobe epilepsy. Cerebral uptake of the muscarinic cholinergic antagonist [123I]4-iododexetimide (IDex) was investigated by SPET in patients suffering from temporal lobe epilepsy of unilateral (n=6) or predominantly unilateral (n=1) onset. Regions of interest were drawn on co-registered magnetic resonance images. Hippocampal volume was determined in these regions and was used to correct the SPET results for partial volume effects. A ratio of hippocampal IDex binding on the affected side to that on the unaffected side was used to detect changes in muscarinic cholinergic receptor density. Before partial volume correction a decrease in hippocampal IDex binding on the focus side was found in each patient. After partial volume no convincing differences remained. Our results indicate that the reduction in hippocampal IDex binding in patients with epilepsy is due to a decrease in hippocampal volume rather than to a decrease in receptor concentration.}, language = {en} } @article{WedrowskiBruyndonckxTavernieretal.2009, author = {Wedrowski, M. and Bruyndonckx, P. and Tavernier, S. and Zhi, L. and Dang, J. and Mendes, P. R. and Perez, J. M. and Ziemons, Karl}, title = {Robustness of neural networks algorithm for gamma detection in monolithic block detector, positron emission tomography}, series = {2009 IEEE Nuclear Science Symposium Conference Record (NSS/MIC)}, journal = {2009 IEEE Nuclear Science Symposium Conference Record (NSS/MIC)}, isbn = {1082-3654}, pages = {2625 -- 2628}, year = {2009}, abstract = {The monolithic scintillator block approach for gamma detection in the Positron Emission Tomography (PET) avoids estimating Depth of Interaction (DOI), reduces dead zones in detector and diminishes costs of detector production. Neural Networks (NN) are very efficient to determine the entrance point of a gamma incident on a scintillator block. This paper presents results on the robustness of the spatial resolution as a function of the random fraction in the data, temperature and HV fluctuations. This is important when implementing the method in a real scanner. Measurements were done with two Hamamatsu S8550 APD arrays, glued on a 20 {\~A}— 20 {\~A}— 10 mm3 monolithic LSO crystal block.}, language = {en} } @article{WeemstraEilmannSassKlaassenetal.2013, author = {Weemstra, Monique and Eilmann, Britta and Sass-Klaassen, Ute G. W. and Sterck, Frank J.}, title = {Summer droughts limit tree growth across 10 temperate species on a productive forest site}, series = {Forest Ecology and Management}, volume = {2013}, journal = {Forest Ecology and Management}, number = {306}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0378-1127 (Print)}, doi = {doi:10.1016/j.foreco.2013.06.007}, pages = {142 -- 149}, year = {2013}, language = {en} } @article{WegmannHacklStaatetal.2016, author = {Wegmann, Kilian and Hackl, Michael and Staat, Manfred and Mayer, Katharina and M{\"u}ller, Lars-Peter}, title = {Double plate osteosynthesis of proximal ulna fractures: biomechanical and clinical results}, series = {Knee surgery, sports traumatology, arthroscopy}, volume = {Volume 24}, journal = {Knee surgery, sports traumatology, arthroscopy}, number = {Supplement 1}, publisher = {Springer}, address = {Berlin}, issn = {0942-2056}, doi = {10.1007/s00167-016-4079-0}, pages = {58 -- 59}, year = {2016}, abstract = {While plate fixation of proximal ulna fractures might lead to superior clinical results compared to tension band wiring, regular plates represent an established risk factor for wound complications. The olecranon double plates (Medartis, Basel, CH) might decrease complications related to the osteosynthesis because of their low profile and better anatomical fit. This study aimed to evaluate the biomechanical performance and clinical results of the olecranon double plates.}, language = {en} } @article{WegnervonArxSassKlaassenetal.2013, author = {Wegner, Lena and von Arx, Georg and Sass-Klaassen, Ute G. W. and Eilmann, Britta}, title = {ROXAS - an efficient and accurate tool to detect vessels in diffuse-porous species}, series = {IAWA Journal / International Association of Wood Anatomists}, volume = {34}, journal = {IAWA Journal / International Association of Wood Anatomists}, number = {4}, publisher = {Brill}, address = {Leiden}, issn = {0928-1541 (Print)}, doi = {10.1163/22941932-00000034}, pages = {425 -- 432}, year = {2013}, language = {en} } @article{Weigand1991, author = {Weigand, Christoph}, title = {A Solution to the Scheduling Problem Taking into Account Quality}, series = {Operations research '91 : extended abstracts of the 16th Symposium on Operations Research held at the University of Trier at September 9 - 11, 1991 / [GM{\"O}OR]. Peter Gritzmann ... (eds.)}, journal = {Operations research '91 : extended abstracts of the 16th Symposium on Operations Research held at the University of Trier at September 9 - 11, 1991 / [GM{\"O}OR]. Peter Gritzmann ... (eds.)}, publisher = {Physica-Verl.}, address = {Heidelberg}, isbn = {3790806080}, pages = {373 -- 375}, year = {1991}, language = {en} } @article{Weigand1990, author = {Weigand, Christoph}, title = {Optimal Adjustment Policies}, series = {Proceedings of the First Ume{\aa}-W{\"u}rzburg Conference in Statistics : Kronlund Conference Center and University of Ume{\aa}, September 10 - 14, 1990 / ed. by Kurt Br{\"a}nn{\"a}s}, journal = {Proceedings of the First Ume{\aa}-W{\"u}rzburg Conference in Statistics : Kronlund Conference Center and University of Ume{\aa}, September 10 - 14, 1990 / ed. by Kurt Br{\"a}nn{\"a}s}, publisher = {Univ. of Ume{\aa}}, address = {Ume{\aa}}, isbn = {91-7174-564-5}, pages = {147 -- 158}, year = {1990}, language = {en} } @article{Weigand2003, author = {Weigand, Christoph}, title = {Technically Optimal Inspection Policy with Arithmetical Adaption}, series = {IMA Journal of Management Mathematics. 14 (2003), H. 4}, journal = {IMA Journal of Management Mathematics. 14 (2003), H. 4}, isbn = {1471-678X}, pages = {357 -- 371}, year = {2003}, language = {en} } @article{Weigand2003, author = {Weigand, Christoph}, title = {Economically Optimal Inspection Policy with Geometrical Adaption}, series = {Journal of Applied Statistics. 30 (2003), H. 5}, journal = {Journal of Applied Statistics. 30 (2003), H. 5}, isbn = {0266-4763}, pages = {555 -- 569}, year = {2003}, language = {en} } @article{Weigand2001, author = {Weigand, Christoph}, title = {Economically Optimal Inspection Policy with Arithmetical Adaption}, series = {Applied stochastic models and data analysis / [10th International Symposium on Applied Stochastic Models and Analysis, June 12-15 2001, Universit{\´e} Technologique de Compi{\`e}gne] ; editors G{\´e}rard Govaert, Jacques Janssen, Nikolaos Limnios.}, journal = {Applied stochastic models and data analysis / [10th International Symposium on Applied Stochastic Models and Analysis, June 12-15 2001, Universit{\´e} Technologique de Compi{\`e}gne] ; editors G{\´e}rard Govaert, Jacques Janssen, Nikolaos Limnios.}, publisher = {Universit{\´e} Technologique de Compi{\`e}gne}, address = {Compi{\`e}gne}, pages = {1010 -- 1015}, year = {2001}, language = {en} } @article{Weigand2000, author = {Weigand, Christoph}, title = {Economically Optimal Adaptive Inspection Policies}, series = {Economic Quality Control. 15 (2000), H. 1/2}, journal = {Economic Quality Control. 15 (2000), H. 1/2}, isbn = {0940-5151}, pages = {55 -- 77}, year = {2000}, language = {en} } @article{Weigand1992, author = {Weigand, Christoph}, title = {Economic Machine Adjustment in the Case of Product Screening .E.v.Collani, Ch. Weigand}, series = {Statistical Papers. 33 (1992)}, journal = {Statistical Papers. 33 (1992)}, pages = {171 -- 184}, year = {1992}, language = {en} } @article{Weigand1993, author = {Weigand, Christoph}, title = {On the Effects of SPC on Production Time}, series = {Economic Quality Control. 8 (1993)}, journal = {Economic Quality Control. 8 (1993)}, isbn = {0940-5151}, pages = {23 -- 61}, year = {1993}, language = {en} } @article{Weigand1992, author = {Weigand, Christoph}, title = {A new Approach for Optimal Control of a Production process}, series = {Economic Quality Control. 7 (1992)}, journal = {Economic Quality Control. 7 (1992)}, isbn = {0940-5151}, pages = {225 -- 251}, year = {1992}, language = {en} } @article{Weigand1994, author = {Weigand, Christoph}, title = {Optimal Production Schedule for a K Products Single Machine Problem}, series = {Economic Quality Control. 9 (1994)}, journal = {Economic Quality Control. 9 (1994)}, isbn = {0940-5151}, pages = {91 -- 101}, year = {1994}, language = {en} } @article{Weigand2012, author = {Weigand, Christoph}, title = {Statistical Tests Based on Reliability and Precision}, series = {Economic Quality Control : EQC ; international journal for quality and reliability}, volume = {27}, journal = {Economic Quality Control : EQC ; international journal for quality and reliability}, number = {1}, publisher = {De Gruyter}, address = {Berlin}, issn = {1869-6147}, doi = {10.1515/eqc-2012-0002}, pages = {43 -- 64}, year = {2012}, abstract = {The construction of a statistical test is investigated which is based only on "reliability" and "precision" as quality criteria. The reliability of a statistical test is quantifiedin a straightforward way by the probability that the decision of the test is correct. However, the quantification of the precision of a statistical test is not at all evident. Thereforethe paper presents and discusses several approaches. Moreover the distinction of "nullhypothesis" and "alternative hypothesis" is not necessary any longer.}, language = {en} } @article{Weigand2009, author = {Weigand, Christoph}, title = {Defining Precisions for Reliable Measurement and Estimation Procedures}, series = {Economic Quality Control. 24 (2009), H. 1}, journal = {Economic Quality Control. 24 (2009), H. 1}, publisher = {De Gruyter}, address = {Berlin}, isbn = {0940-5151}, pages = {5 -- 33}, year = {2009}, language = {en} } @article{WeigandCollaniSaniga1994, author = {Weigand, Christoph and Collani, E. v. and Saniga, E.M.}, title = {Economic Adjustment Design for -Control Charts. E.v.Collani, E.M. Saniga, Ch. Weigand}, series = {IIE Transactions / Institute of Industrial Engineers. 26 (1994), H. 6}, journal = {IIE Transactions / Institute of Industrial Engineers. 26 (1994), H. 6}, isbn = {0569-5554}, year = {1994}, language = {en} } @article{WeldenPoghossianVahidpouretal.2022, author = {Welden, Melanie and Poghossian, Arshak and Vahidpour, Farnoosh and Wendlandt, Tim and Keusgen, Michael and Wege, Christina and Sch{\"o}ning, Michael Josef}, title = {Towards multi-analyte detection with field-effect capacitors modified with tobacco mosaic virus bioparticles as enzyme nanocarriers}, series = {Biosensors}, volume = {12}, journal = {Biosensors}, number = {1}, publisher = {MDPI}, address = {Basel}, issn = {2079-6374}, doi = {10.3390/bios12010043}, pages = {Artikel 43}, year = {2022}, abstract = {Utilizing an appropriate enzyme immobilization strategy is crucial for designing enzyme-based biosensors. Plant virus-like particles represent ideal nanoscaffolds for an extremely dense and precise immobilization of enzymes, due to their regular shape, high surface-to-volume ratio and high density of surface binding sites. In the present work, tobacco mosaic virus (TMV) particles were applied for the co-immobilization of penicillinase and urease onto the gate surface of a field-effect electrolyte-insulator-semiconductor capacitor (EISCAP) with a p-Si-SiO₂-Ta₂O₅ layer structure for the sequential detection of penicillin and urea. The TMV-assisted bi-enzyme EISCAP biosensor exhibited a high urea and penicillin sensitivity of 54 and 85 mV/dec, respectively, in the concentration range of 0.1-3 mM. For comparison, the characteristics of single-enzyme EISCAP biosensors modified with TMV particles immobilized with either penicillinase or urease were also investigated. The surface morphology of the TMV-modified Ta₂O₅-gate was analyzed by scanning electron microscopy. Additionally, the bi-enzyme EISCAP was applied to mimic an XOR (Exclusive OR) enzyme logic gate.}, language = {en} } @article{WeldenSeverinsPoghossianetal.2022, author = {Welden, Melanie and Severins, Robin and Poghossian, Arshak and Wege, Christina and Bongaerts, Johannes and Siegert, Petra and Keusgen, Michael and Sch{\"o}ning, Michael Josef}, title = {Detection of acetoin and diacetyl by a tobacco mosaic virus-assisted field-effect biosensor}, series = {Chemosensors}, volume = {10}, journal = {Chemosensors}, number = {6}, publisher = {MDPI}, address = {Basel}, issn = {2227-9040}, doi = {10.3390/chemosensors10060218}, pages = {Artikel 218}, year = {2022}, abstract = {Acetoin and diacetyl have a major impact on the flavor of alcoholic beverages such as wine or beer. Therefore, their measurement is important during the fermentation process. Until now, gas chromatographic techniques have typically been applied; however, these require expensive laboratory equipment and trained staff, and do not allow for online monitoring. In this work, a capacitive electrolyte-insulator-semiconductor sensor modified with tobacco mosaic virus (TMV) particles as enzyme nanocarriers for the detection of acetoin and diacetyl is presented. The enzyme acetoin reductase from Alkalihalobacillus clausii DSM 8716ᵀ is immobilized via biotin-streptavidin affinity, binding to the surface of the TMV particles. The TMV-assisted biosensor is electrochemically characterized by means of leakage-current, capacitance-voltage, and constant capacitance measurements. In this paper, the novel biosensor is studied regarding its sensitivity and long-term stability in buffer solution. Moreover, the TMV-assisted capacitive field-effect sensor is applied for the detection of diacetyl for the first time. The measurement of acetoin and diacetyl with the same sensor setup is demonstrated. Finally, the successive detection of acetoin and diacetyl in buffer and in diluted beer is studied by tuning the sensitivity of the biosensor using the pH value of the measurement solution.}, language = {en} } @article{WeldenJablonskiWegeetal.2021, author = {Welden, Rene and Jablonski, Melanie and Wege, Christina and Keusgen, Michael and Wagner, Patrick Hermann and Wagner, Torsten and Sch{\"o}ning, Michael Josef}, title = {Light-Addressable Actuator-Sensor Platform for Monitoring and Manipulation of pH Gradients in Microfluidics: A Case Study with the Enzyme Penicillinase}, series = {Biosensors}, volume = {11}, journal = {Biosensors}, number = {6}, publisher = {MDPI}, address = {Basel}, issn = {2079-6374}, doi = {10.3390/bios11060171}, pages = {Artikel 171}, year = {2021}, abstract = {The feasibility of light-addressed detection and manipulation of pH gradients inside an electrochemical microfluidic cell was studied. Local pH changes, induced by a light-addressable electrode (LAE), were detected using a light-addressable potentiometric sensor (LAPS) with different measurement modes representing an actuator-sensor system. Biosensor functionality was examined depending on locally induced pH gradients with the help of the model enzyme penicillinase, which had been immobilized in the microfluidic channel. The surface morphology of the LAE and enzyme-functionalized LAPS was studied by scanning electron microscopy. Furthermore, the penicillin sensitivity of the LAPS inside the microfluidic channel was determined with regard to the analyte's pH influence on the enzymatic reaction rate. In a final experiment, the LAE-controlled pH inhibition of the enzyme activity was monitored by the LAPS.}, language = {en} } @article{WeldenSchejaSchoeningetal.2018, author = {Welden, Rene and Scheja, Sabrina and Sch{\"o}ning, Michael Josef and Wagner, Patrick and Wagner, Torsten}, title = {Electrochemical Evaluation of Light-Addressable Electrodes Based on TiO2 for the Integration in Lab-on-Chip Systems}, series = {physica status solidi a : applications and materials sciences}, volume = {215}, journal = {physica status solidi a : applications and materials sciences}, number = {15}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {1862-6319}, doi = {10.1002/pssa.201800150}, pages = {Article number 1800150}, year = {2018}, abstract = {In lab-on-chip systems, electrodes are important for the manipulation (e.g., cell stimulation, electrolysis) within such systems. An alternative to commonly used electrode structures can be a light-addressable electrode. Here, due to the photoelectric effect, the conducting area can be adjusted by modification of the illumination area which enables a flexible control of the electrode. In this work, titanium dioxide based light-addressable electrodes are fabricated by a sol-gel technique and a spin-coating process, to deposit a thin film on a fluorine-doped tin oxide glass. To characterize the fabricated electrodes, the thickness, and morphological structure are measured by a profilometer and a scanning electron microscope. For the electrochemical behavior, the dark current and the photocurrent are determined for various film thicknesses. For the spatial resolution behavior, the dependency of the photocurrent while changing the area of the illuminated area is studied. Furthermore, the addressing of single fluid compartments in a three-chamber system, which is added to the electrode, is demonstrated.}, language = {en} } @article{WeldenSchoeningWagneretal.2020, author = {Welden, Rene and Sch{\"o}ning, Michael Josef and Wagner, Patrick H. and Wagner, Torsten}, title = {Light-Addressable Electrodes for Dynamic and Flexible Addressing of Biological Systems and Electrochemical Reactions}, series = {Sensors}, volume = {20}, journal = {Sensors}, number = {6}, publisher = {MDPI}, address = {Basel}, issn = {1424-8220}, doi = {10.3390/s20061680}, pages = {Artikel 1680}, year = {2020}, abstract = {In this review article, we are going to present an overview on possible applications of light-addressable electrodes (LAE) as actuator/manipulation devices besides classical electrode structures. For LAEs, the electrode material consists of a semiconductor. Illumination with a light source with the appropiate wavelength leads to the generation of electron-hole pairs which can be utilized for further photoelectrochemical reaction. Due to recent progress in light-projection technologies, highly dynamic and flexible illumination patterns can be generated, opening new possibilities for light-addressable electrodes. A short introduction on semiconductor-electrolyte interfaces with light stimulation is given together with electrode-design approaches. Towards applications, the stimulation of cells with different electrode materials and fabrication designs is explained, followed by analyte-manipulation strategies and spatially resolved photoelectrochemical deposition of different material types.}, language = {en} } @article{WemhoenerHafnerSchwarzer2000, author = {Wemh{\"o}ner, Carsten and Hafner, Bernd and Schwarzer, Klemens}, title = {Simulation of solar thermal systems with CARNOT blockset in the environment MATLAB-Simulink}, pages = {1 -- 6}, year = {2000}, language = {en} } @article{WendlandtKochBritzetal.2023, author = {Wendlandt, Tim and Koch, Claudia and Britz, Beate and Liedek, Anke and Schmidt, Nora and Werner, Stefan and Gleba, Yuri and Vahidpour, Farnoosh and Welden, Melanie and Poghossian, Arshak and Sch{\"o}ning, Michael Josef}, title = {Facile Purification and Use of Tobamoviral Nanocarriers for Antibody-Mediated Display of a Two-Enzyme System}, series = {Viruses}, volume = {9}, journal = {Viruses}, number = {15}, publisher = {MDPI}, address = {Basel}, issn = {1999-4915}, doi = {doi.org/10.3390/v15091951}, pages = {Artikel 1951}, year = {2023}, abstract = {Immunosorbent turnip vein clearing virus (TVCV) particles displaying the IgG-binding domains D and E of Staphylococcus aureus protein A (PA) on every coat protein (CP) subunit (TVCVPA) were purified from plants via optimized and new protocols. The latter used polyethylene glycol (PEG) raw precipitates, from which virions were selectively re-solubilized in reverse PEG concentration gradients. This procedure improved the integrity of both TVCVPA and the wild-type subgroup 3 tobamovirus. TVCVPA could be loaded with more than 500 IgGs per virion, which mediated the immunocapture of fluorescent dyes, GFP, and active enzymes. Bi-enzyme ensembles of cooperating glucose oxidase and horseradish peroxidase were tethered together on the TVCVPA carriers via a single antibody type, with one enzyme conjugated chemically to its Fc region, and the other one bound as a target, yielding synthetic multi-enzyme complexes. In microtiter plates, the TVCVPA-displayed sugar-sensing system possessed a considerably increased reusability upon repeated testing, compared to the IgG-bound enzyme pair in the absence of the virus. A high coverage of the viral adapters was also achieved on Ta2O5 sensor chip surfaces coated with a polyelectrolyte interlayer, as a prerequisite for durable TVCVPA-assisted electrochemical biosensing via modularly IgG-assembled sensor enzymes.}, language = {en} } @article{WerfelGuenthnerHapfelmeieretal.2022, author = {Werfel, Stanislas and G{\"u}nthner, Roman and Hapfelmeier, Alexander and Hanssen, Henner and Kotliar, Konstantin and Heemann, Uwe and Schmaderer, Christoph}, title = {Identification of cardiovascular high-risk groups from dynamic retinal vessel signals using untargeted machine learning}, series = {Cardiovascular Research}, volume = {118}, journal = {Cardiovascular Research}, number = {2}, editor = {Guzik, Tomasz J.}, publisher = {Oxford University Press}, address = {Oxford}, issn = {0008-6363}, doi = {10.1093/cvr/cvab040}, pages = {612 -- 621}, year = {2022}, abstract = {Dynamic retinal vessel analysis (DVA) provides a non-invasive way to assess microvascular function in patients and potentially to improve predictions of individual cardiovascular (CV) risk. The aim of our study was to use untargeted machine learning on DVA in order to improve CV mortality prediction and identify corresponding response alterations.}, language = {en} } @article{WerkhausenAlbrachtCroninetal.2018, author = {Werkhausen, Amelie and Albracht, Kirsten and Cronin, Neil J and Paulsen, G{\o}ran and Bojsen-M{\o}ller, Jens and Seynnes, Olivier R}, title = {Effect of training-induced changes in achilles tendon stiffness on muscle-tendon behavior during landing}, series = {Frontiers in physiology}, journal = {Frontiers in physiology}, number = {9}, publisher = {Frontiers Research Foundation}, address = {Lausanne}, issn = {1664-042X}, doi = {10.3389/fphys.2018.00794}, pages = {11 Seiten}, year = {2018}, abstract = {During rapid deceleration of the body, tendons buffer part of the elongation of the muscle-tendon unit (MTU), enabling safe energy dissipation via eccentric muscle contraction. Yet, the influence of changes in tendon stiffness within the physiological range upon these lengthening contractions is unknown. This study aimed to examine the effect of training-induced stiffening of the Achilles tendon on triceps surae muscle-tendon behavior during a landing task. Twenty-one male subjects were assigned to either a 10-week resistance-training program consisting of single-leg isometric plantarflexion (n = 11) or to a non-training control group (n = 10). Before and after the training period, plantarflexion force, peak Achilles tendon strain and stiffness were measured during isometric contractions, using a combination of dynamometry, ultrasound and kinematics data. Additionally, testing included a step-landing task, during which joint mechanics and lengths of gastrocnemius and soleus fascicles, Achilles tendon, and MTU were determined using synchronized ultrasound, kinematics and kinetics data collection. After training, plantarflexion strength and Achilles tendon stiffness increased (15 and 18\%, respectively), and tendon strain during landing remained similar. Likewise, lengthening and negative work produced by the gastrocnemius MTU did not change detectably. However, in the training group, gastrocnemius fascicle length was offset (8\%) to a longer length at touch down and, surprisingly, fascicle lengthening and velocity were reduced by 27 and 21\%, respectively. These changes were not observed for soleus fascicles when accounting for variation in task execution between tests. These results indicate that a training-induced increase in tendon stiffness does not noticeably affect the buffering action of the tendon when the MTU is rapidly stretched. Reductions in gastrocnemius fascicle lengthening and lengthening velocity during landing occurred independently from tendon strain. Future studies are required to provide insight into the mechanisms underpinning these observations and their influence on energy dissipation.}, language = {en} }