@incollection{KochPoghossianWegeetal.2018,
  author    = {Koch, Claudia and Poghossian, Arshak and Wege, Christina and Sch{\"o}ning, Michael Josef},
  title     = {TMV-Based Adapter Templates for Enhanced Enzyme Loading in Biosensor Applications},
  series = {Virus-Derived Nanoparticles for Advanced Technologies},
  booktitle = {Virus-Derived Nanoparticles for Advanced Technologies},
  editor    = {Wege, Christina},
  publisher = {Humana Press},
  address   = {New York, NY},
  isbn      = {978-1-4939-7808-3},
  doi       = {10.1007/978-1-4939-7808-3},
  pages     = {553 -- 568},
  year      = {2018},
  abstract  = {Nanotubular tobacco mosaic virus (TMV) particles and RNA-free lower-order coat protein (CP) aggregates have been employed as enzyme carriers in different diagnostic layouts and compared for their influence on biosensor performance. In the following, we describe a label-free electrochemical biosensor for improved glucose detection by use of TMV adapters and the enzyme glucose oxidase (GOD). A specific and efficient immobilization of streptavidin-conjugated GOD ([SA]-GOD) complexes on biotinylated TMV nanotubes or CP aggregates was achieved via bioaffinity binding. Glucose sensors with adsorptively immobilized [SA]-GOD, and with [SA]-GOD cross-linked with glutardialdehyde, respectively, were tested in parallel on the same sensor chip. Comparison of these sensors revealed that TMV adapters enhanced the amperometric glucose detection remarkably, conveying highest sensitivity, an extended linear detection range and fastest response times. These results underline a great potential of an integration of virus/biomolecule hybrids with electronic transducers for applications in biosensorics and biochips. Here, we describe the fabrication and use of amperometric sensor chips combining an array of circular Pt electrodes, their loading with GOD-modified TMV nanotubes (and other GOD immobilization methods), and the subsequent investigations of the sensor performance.},
  language  = {en}
}
@article{KohlerKirschnerHermannsStaatetal.2018,
  author    = {Kohler, Annette and Kirschner-Hermanns, Ruth and Staat, Manfred and Brehmer, Bernhard},
  title     = {Pathogenese, funktionelle und anatomische Aspekte der weiblichen Belastungsinkontinenz},
  series = {Aktuelle Urologie},
  volume    = {49},
  journal   = {Aktuelle Urologie},
  number    = {1},
  publisher = {Thieme},
  address   = {Stuttgart},
  issn      = {1438-8820},
  doi       = {10.1055/s-0043-120616},
  pages     = {47 -- 51},
  year      = {2018},
  abstract  = {Der vorliegende Artikel fokussiert sich auf die weibliche Belastungsinkontinenz als Insuffizienz der Speicherfunktion der Blase, auch wenn im klinischen Alltag die Harninkontinenz der Frau h{\"a}ufig verschiedene Ursachen hat und insbesondere eine Belastungsinkontinenz im Alter und bei neurologischer Komorbidit{\"a}t nur selten isoliert vorkommt. Das kleine Becken der Frau ist sowohl als Funktions- als auch als strukturelle Einheit zu betrachten. Dabei unterliegen bei der Frau Blase, Harnr{\"o}hre, Geb{\"a}rmutter und Enddarm sowie die muskul{\"a}ren und ligament{\"o}sen Strukturen des kleinen Beckens durch Fertilit{\"a}tsphase, m{\"o}gliche Schwangerschaften, Geburten und Menopausen-Phase, {\"u}ber das „normale Altern" hinaus, gravierenden Ver{\"a}nderungen. This article focuses on female stress incontinence in the form of pelvic floor dysfunction and urethral sphincter deficiency, although isolated stress incontinence accounts for less than half of all incontinence cases. Especially in women of old age and those with neurological comorbidities, the causes of incontinence are mostly multifactorial. Also it has to be considered that the female bladder, urethra, uterus and rectum as well as the muscular and ligamentous structures of the female pelvis minor are affected by phases of fertility, possible pregnancies, births and menopause in addition to the normal ageing process.},
  language  = {de}
}
@article{KotliarLanzl2018,
  author    = {Kotliar, Konstantin and Lanzl, Ines},
  title     = {Vaskul{\"a}re Biomarker der retinalen Gef{\"a}βanalyse},
  series = {Klinische Monatsbl{\"a}tter fur Augenheilkunde},
  volume    = {235},
  journal   = {Klinische Monatsbl{\"a}tter fur Augenheilkunde},
  number    = {12},
  publisher = {Thieme},
  address   = {Stuttgart},
  issn      = {0023-2165},
  doi       = {10.1055/a-0774-7987},
  pages     = {1352 -- 1359},
  year      = {2018},
  abstract  = {Mit modernen nicht invasiven bildgebenden Verfahren lassen sich anhand der Fundusfotografie bzw. der optischen Verfilmung Aspekte der funktionellen und strukturellen retinalen Gef{\"a}ßver{\"a}nderungen objektiv untersuchen. Der Zustand und das Verhalten retinaler Gef{\"a}ße beeinflussen im pr{\"a}-, post- und kapillaren Bereich den Blutfluss und str{\"o}mungsbedingte Stoffwechselverh{\"a}ltnisse passiv und aktiv {\"u}ber den Gef{\"a}ßdurchmesser. Retinale Gef{\"a}ße gleichen von Aufbau und Funktion den zerebralen Gef{\"a}ßen und spiegeln den Zustand der Mikrozirkulation wider. Mithilfe von aus den Gef{\"a}ßweiten berechneten Biomarkern soll eine Aussage {\"u}ber die Prognose von systemischen vaskul{\"a}r bedingten Erkrankungen getroffen werden. Die statische retinale Gef{\"a}ßanalyse befasst sich mit der Untersuchung des Zustandes der pr{\"a}- und postkapillaren Gef{\"a}ßdurchmesser der retinalen Mikrozirkulation anhand einer optischen Fundusaufnahme. Bei der dynamischen retinalen Gef{\"a}ßanalyse wird der L{\"a}ngsschnitt eines retinalen Gef{\"a}ßes nicht invasiv funktionell und strukturell {\"u}ber einen Zeitraum vor, w{\"a}hrend und nach einer spezifischen vaskul{\"a}ren Stimulation untersucht. Die genaue Methodologie der Auswertung und die Bezeichnung der Parameter variieren bei unterschiedlichen Ans{\"a}tzen. Mittels retinaler Gef{\"a}ßanalyse wurden bislang mehrere klinische Querschnitts- und Interventionsstudien in der Augenheilkunde und anderen Fachgebieten, inkl. Kardiologie, Neurologie, Neurochirurgie, Nephrologie, Gyn{\"a}kologie, Sportmedizin, Diabetologie, Hypertensiologie usw. durchgef{\"u}hrt. Mit der statischen retinalen Gef{\"a}ßanalyse steht eine kosteng{\"u}nstige, reproduzierbare, nicht invasive Screeningtechnik zur Verf{\"u}gung, um eine prognostische Aussage {\"u}ber die Gef{\"a}ßgesundheit eines individuellen Patienten zu treffen. Die dynamische retinale Gef{\"a}ßanalyse besitzt ein weiteres diagnostisches Anwendungsspektrum als die statische, da sie das Verhalten retinaler Gef{\"a}ße zeitkontinuierlich untersucht. Die Evaluation vaskul{\"a}rer Erkrankungen sowie zerebro- bzw. kardiovaskul{\"a}rer Morbidit{\"a}t und Mortalit{\"a}t mittels mehrerer methodologischer Modalit{\"a}ten retinaler Gef{\"a}ßanalyse mit ihren jeweiligen quantitativen Biomarkern bietet eine zukunftstr{\"a}chtige diagnostische Perspektive. Die interdisziplin{\"a}re klinische Anwendung dieser vaskul{\"a}ren Biomarker gewinnt zunehmend an Bedeutung, sowohl in der Augenheilkunde als auch in anderen Fachgebieten.},
  language  = {de}
}
@inproceedings{KromeSander2018,
  author    = {Krome, Cornelia and Sander, Volker},
  title     = {Time series analysis with apache spark and its applications to energy informatics},
  series = {Proceedings of the 7th DACH+ Conference on Energy Informatics},
  booktitle = {Proceedings of the 7th DACH+ Conference on Energy Informatics},
  doi       = {10.1186/s42162-018-0043-1},
  year      = {2018},
  abstract  = {In energy economy forecasts of different time series are rudimentary. In this study, a prediction for the German day-ahead spot market is created with Apache Spark and R. It is just an example for many different applications in virtual power plant environments. Other examples of use as intraday price processes, load processes of machines or electric vehicles, real time energy loads of photovoltaic systems and many more time series need to be analysed and predicted. This work gives a short introduction into the project where this study is settled. It describes the time series methods that are used in energy industry for forecasts shortly. As programming technique Apache Spark, which is a strong cluster computing technology, is utilised. Today, single time series can be predicted. The focus of this work is on developing a method to parallel forecasting, to process multiple time series simultaneously with R and Apache Spark.},
  language  = {en}
}
@article{KunkelGebhardtMpofuetal.2018,
  author    = {Kunkel, Maximilian Hugo and Gebhardt, Andreas and Mpofu, Khumbaulani and Kallweit, Stephan},
  title     = {Statistical assessment of mechanical properties of selective laser melted specimens of stainless steel},
  series = {The International Journal of Advanced Manufacturing Technology},
  volume    = {98},
  journal   = {The International Journal of Advanced Manufacturing Technology},
  number    = {5-8},
  publisher = {Springer},
  address   = {London},
  issn      = {0268-3768},
  doi       = {10.1007/s00170-018-2040-8},
  pages     = {1409 -- 1431},
  year      = {2018},
  abstract  = {The rail business is challenged by long product life cycles and a broad spectrum of assembly groups and single parts. When spare part obsolescence occurs, quick solutions are needed. A reproduction of obsolete parts is often connected to long waiting times and minimum lot quantities that need to be purchased and stored. Spare part storage is therefore challenged by growing stocks, bound capital and issues of part ageing. A possible solution could be a virtual storage of spare parts which will be 3D printed through additive manufacturing technologies in case of sudden demand. As mechanical properties of additive manufactured parts are neither guaranteed by machine manufacturers nor by service providers, the utilization of this relatively young technology is impeded and research is required to address these issues. This paper presents an examination of mechanical properties of specimens manufactured from stainless steel through the selective laser melting (SLM) process. The specimens were produced in multiple batches. This paper interrogates the question if the test results follow a normal distribution pattern and if mechanical property predictions can be made. The results will be put opposite existing threshold values provided as the industrial standard. Furthermore, probability predictions will be made in order to examine the potential of the SLM process to maintain state-of-the-art mechanical property requirements.},
  language  = {en}
}
@book{Kurz2018,
  author    = {Kurz, Melanie},
  title     = {Designstreit : exemplarische Kontroversen {\"u}ber Gestaltung},
  publisher = {Wilhelm Fink},
  address   = {Paderborn},
  isbn      = {978-3-7705-6294-7 (Druckausgabe)},
  pages     = {304 Seiten},
  year      = {2018},
  abstract  = {Die Geschichte des Designs ist ges{\"a}umt von Auseinandersetzungen. Debattiert wird unter Berufsgenossen, in Interessensverb{\"a}nden, zwischen Wettbewerbern und nicht zuletzt an Hochschulen; als Foren dienen zum Beispiel Zeitungen, Konferenzen oder Gerichtss{\"a}le. Doch welche Gr{\"u}nde gibt es f{\"u}r Streit {\"u}ber Design? Die Kontroversen beschr{\"a}nken sich keineswegs auf die {\"A}sthetik von Artefakten. Auch haben wir es trotz der Vielfalt an Streitf{\"a}llen nicht mit einem un{\"u}berschaubaren Feld von zusammenhanglosen Einzelereignissen zu tun. Wie das vorliegende Buch anhand historischer Kontroversen zeigt, lassen sich im Bereich der Gestaltung Streitkategorien identifizieren. Die Diskursanalyse verr{\"a}t, dass sich die Konfliktursachen im Verlauf der Designhistorie kaum ver{\"a}ndern. So haben die angef{\"u}hrten Dispute erstaunliche {\"A}hnlichkeit mit aktuellen Debatten im Fach. Sie sind Lehrst{\"u}cke und k{\"o}nnen dazu anregen, eine Streitkultur im Design zu etablieren, die sich davon distanziert, den Meinungsgegner in ein politisches Lager zu ›verr{\"a}umen‹.},
  language  = {de}
}
@article{Kurz2018,
  author    = {Kurz, Melanie},
  title     = {Was heißt: Verantwortung im Design? Historische Positionen},
  series = {Boxhorn: das Magazin aus dem Fachbereich Gestaltung der FH Aachen},
  journal   = {Boxhorn: das Magazin aus dem Fachbereich Gestaltung der FH Aachen},
  number    = {34},
  address   = {Aachen},
  pages     = {26 -- 33},
  year      = {2018},
  language  = {de}
}
@inproceedings{KoenigVoelkerWolf2018,
  author    = {K{\"o}nig, Johannes Alexander and V{\"o}lker, Veronika and Wolf, Martin},
  title     = {The user-focused storybuilding framework for competence developing games - a design-framework considering the basics of an educational game's story},
  series = {ACHI 2018 : The Eleventh International Conference on Advances in Computer-Human Interactions},
  booktitle = {ACHI 2018 : The Eleventh International Conference on Advances in Computer-Human Interactions},
  isbn      = {978-1-61208-616-3},
  pages     = {98 -- 106},
  year      = {2018},
  abstract  = {During the development of a Competence Developing Game's (CDG) story it is indispensable to understand the target audience. Thereby, CDGs stories represent more than just the plot. The Story is about the Setting, the Characters and the Plot. As a toolkit to support the development of such a story, this paper introduces the UserFocused Storybuilding (short UFoS) Framework for CDGs. The Framework and its utilization will be explained, followed by a description of its development and derivation, including an empirical study. In addition, to simplify the Framework use regarding the CDG's target audience, a new concept of Nine Psychographic Player Types will be explained. This concept of Player Types provides an approach to handle the differences in between players during the UFoS Framework use. Thereby, this article presents a unique approach to the development of target group-differentiated CDGs stories.},
  language  = {en}
}
@article{KoenigWolf2018,
  author    = {K{\"o}nig, Johannes Alexander and Wolf, Martin},
  title     = {GHOST: An Evaluated Competence Developing Game for Cybersecurity Awareness Training},
  series = {International Journal on Advances in Security},
  volume    = {11},
  journal   = {International Journal on Advances in Security},
  number    = {3 \& 4},
  publisher = {IARIA Journals},
  issn      = {1942-2636},
  pages     = {274 -- 287},
  year      = {2018},
  abstract  = {To train end users how to interact with digital systems is indispensable to ensure a strong computer security. 'Competence Developing Game'-based approaches are particularly suitable for this purpose because of their motivation-and simulation-aspects. In this paper the Competence Developing Game 'GHOST' for cybersecurity awareness trainings and its underlying patterns are described. Accordingly, requirements for an 'Competence Developing Game' based training are discussed. Based on these requirements it is shown how a game can fulfill these requirements. A supplementary game interaction design and a corresponding evaluation study is shown. The combination of training requirements and interaction design is used to create a 'Competence Developing Game'-based training concept. A part of these concept is implemented into a playable prototype that serves around one hour of play respectively training time. This prototype is used to perform an evaluation of the game and training aspects of the awareness training. Thereby, the quality of the game aspect and the effectiveness of the training aspect are shown.},
  language  = {en}
}
@inproceedings{KoenigWolf2018,
  author    = {K{\"o}nig, Johannes Alexander and Wolf, Martin},
  title     = {Cybersecurity awareness training provided by the competence developing game GHOST},
  series = {ACHI 2018 : The Eleventh International Conference on Advances in Computer-Human Interactions},
  booktitle = {ACHI 2018 : The Eleventh International Conference on Advances in Computer-Human Interactions},
  isbn      = {978-1-61208-616-3},
  pages     = {81 -- 87},
  year      = {2018},
  abstract  = {This paper introduces a Competence Developing Game (CDG) for the purpose of a cybersecurity awareness training for businesses. The target audience will be discussed in detail to understand their requirements. It will be explained why and how a mix of business simulation and serious game meets these stakeholder requirements. It will be shown that a tablet and touchscreen based approach is the most suitable solution. In addition, an empirical study will be briefly presented. The study was carried out to examine how an interaction system for a 3D-tablet based CDG has to be designed, to be manageable for non-game experienced employees. Furthermore, it will be explained which serious content is necessary for a Cybersecurity awareness training CDG and how this content is wrapped in the game},
  language  = {en}
}
@book{Laack2018,
  author    = {Laack, Walter van},
  title     = {Sterben und Tod aus wissenschaftlicher Sicht - dying and death from a scientific point of view},
  publisher = {van Laack GmbH},
  address   = {Aachen},
  isbn      = {978-3-936624-41-0},
  pages     = {44 Seiten},
  year      = {2018},
  language  = {de}
}
@article{LapitanRogatkinPersheyevetal.2018,
  author    = {Lapitan, Denis G. and Rogatkin, Dmitrii A. and Persheyev, Sydulla K. and Kotliar, Konstantin},
  title     = {False spectra formation in the differential two-channel scheme of the laser Doppler flowmeter},
  series = {Biomedizinische Technik},
  volume    = {63},
  journal   = {Biomedizinische Technik},
  number    = {4},
  publisher = {De Gruyter},
  address   = {Berlin},
  issn      = {0013-5585},
  doi       = {10.1515/bmt-2017-0060},
  pages     = {439 -- 444},
  year      = {2018},
  abstract  = {Noise in the differential two-channel scheme of a classic laser Doppler flowmetry (LDF) instrument was studied. Formation of false spectral components in the output signal due to beating of electrical signals in the differential amplifier was found out. The improved block-diagram of the flowmeter was developed allowing to reduce the noise.},
  language  = {en}
}
@article{LauraDrechslerErdtetal.2018,
  author    = {Laura, C.O. and Drechsler, Klaus and Erdt, M. and Wesarg, S. and Bale, R.},
  title     = {Intervention assessment tool for primary tumors in the liver},
  series = {Current Directions in Biomedical Engineering},
  volume    = {4},
  journal   = {Current Directions in Biomedical Engineering},
  number    = {1},
  publisher = {De Gruyter},
  address   = {Berlin},
  issn      = {2364-5504},
  doi       = {10.1515/cdbme-2018-0081},
  pages     = {337 -- 340},
  year      = {2018},
  abstract  = {After a liver tumor intervention the medical doctor has to compare both pre and postoperative CT acquisitions to ensure that all carcinogenic cells are destroyed. A correct assessment of the intervention is of vital importance, since it will reduce the probability of tumor recurrence. Some methods have been proposed to support the medical doctors during the assessment process, however, all of them focus on secondary tumors. In this paper a tool is presented that enables the outcome validation for both primary and secondary tumors. Therefore, a multiphase registration (preoperative arterial and portal phases) followed by a registration between the pre and postoperative CT images is carried out. The first registration is in charge of the primary tumors that are only visible in the arterial phase. The secondary tumors will be incorporated in the second registration step. Finally, the part of the tumor that was not covered by the necrosis is quantified and visualized. The method has been tested in 9 patients, with an average registration error of 1.41 mm.},
  language  = {en}
}
@inproceedings{LeiseAltherr2018,
  author    = {Leise, Philipp and Altherr, Lena},
  title     = {Optimizing the design and control of decentralized water supply systems - a case-study of a hotel building},
  series = {EngOpt 2018 Proceedings of the 6th International Conference on Engineering Optimization},
  booktitle = {EngOpt 2018 Proceedings of the 6th International Conference on Engineering Optimization},
  publisher = {Springer},
  address   = {Cham},
  isbn      = {978-3-319-97773-7},
  doi       = {10.1007/978-3-319-97773-7_107},
  pages     = {1241 -- 1252},
  year      = {2018},
  abstract  = {To increase pressure to supply all floors of high buildings with water, booster stations, normally consisting of several parallel pumps in the basement, are used. In this work, we demonstrate the potential of a decentralized pump topology regarding energy savings in water supply systems of skyscrapers. We present an approach, based on Mixed-Integer Nonlinear Programming, that allows to choose an optimal network topology and optimal pumps from a predefined construction kit comprising different pump types. Using domain-specific scaling laws and Latin Hypercube Sampling, we generate different input sets of pump types and compare their impact on the efficiency and cost of the total system design. As a realistic application example, we consider a hotel building with 325 rooms, 12 floors and up to four pressure zones.},
  language  = {en}
}
@inproceedings{LeiseAltherrPelz2018,
  author    = {Leise, Philipp and Altherr, Lena and Pelz, Peter F.},
  title     = {Technical Operations Research (TOR) - Algorithms, not Engineers, Design Optimal Energy Efficient and Resilient Cooling Systems},
  series = {FAN2018 - Proceedings of the International Conference on Fan Noise, Aerodynamics, Applications and Systems},
  booktitle = {FAN2018 - Proceedings of the International Conference on Fan Noise, Aerodynamics, Applications and Systems},
  pages     = {1 -- 12},
  year      = {2018},
  abstract  = {The overall energy efficiency of ventilation systems can be improved by considering not only single components, but by considering as well the interplay between every part of the system. With the help of the method "TOR" ("Technical Operations Research"), which was developed at the Chair of Fluid Systems at TU Darmstadt, it is possible to improve the energy efficiency of the whole system by considering all possible design choices programmatically. We show the ability of this systematic design approach with a ventilation system for buildings as a use case example. Based on a Mixed-Integer Nonlinear Program (MINLP) we model the ventilation system. We use binary variables to model the selection of different pipe diameters. Multiple fans are model with the help of scaling laws. The whole system is represented by a graph, where the edges represent the pipes and fans and the nodes represents the source of air for cooling and the sinks, that have to be cooled. At the beginning, the human designer chooses a construction kit of different suitable fans and pipes of different diameters and different load cases. These boundary conditions define a variety of different possible system topologies. It is not possible to consider all topologies by hand. With the help of state of the art solvers, on the other side, it is possible to solve this MINLP. Next to this, we also consider the effects of malfunctions in different components. Therefore, we show a first approach to measure the resilience of the shown example use case. Further, we compare the conventional approach with designs that are more resilient. These more resilient designs are derived by extending the before mentioned model with further constraints, that consider explicitly the resilience of the overall system. We show that it is possible to design resilient systems with this method already in the early design stage and compare the energy efficiency and resilience of these different system designs.},
  language  = {en}
}
@incollection{LeiseAltherrPelz2018,
  author    = {Leise, Philipp and Altherr, Lena and Pelz, Peter F.},
  title     = {Energy-Efficient design of a water supply system for skyscrapers by mixed-integer nonlinear programming},
  series = {Operations Research Proceedings 2017},
  booktitle = {Operations Research Proceedings 2017},
  publisher = {Springer},
  address   = {Cham},
  isbn      = {978-3-319-89919-0},
  doi       = {10.1007/978-3-319-89920-6_63},
  year      = {2018},
  abstract  = {The energy-efficiency of technical systems can be improved by a systematic design approach. Technical Operations Research (TOR) employs methods known from Operations Research to find a global optimal layout and operation strategy of technical systems. We show the practical usage of this approach by the systematic design of a decentralized water supply system for skyscrapers. All possible network options and operation strategies are modeled by a Mixed-Integer Nonlinear Program. We present the optimal system found by our approach and highlight the energy savings compared to a conventional system design.},
  language  = {en}
}
@article{Lind2018,
  author    = {Lind, Thorsten Patric},
  title     = {Neues zur Gesch{\"a}ftsf{\"u}hrerhaftung nach \S 64 GmbHG - Zugleich Anmerkung zu BGH vom 19.12.2017 - II ZR 88/16, DB 2018 S. 307, und vom 04.07.2017 - II ZR 319/15, DB 2017 S. 1959 -},
  series = {Der Betrieb},
  journal   = {Der Betrieb},
  number    = {17},
  publisher = {Fachmedien Otto Schmidt},
  address   = {D{\"u}sseldorf},
  issn      = {0005-9935},
  pages     = {1003 -- 1008},
  year      = {2018},
  language  = {de}
}
@misc{Lind2018,
  author    = {Lind, Thorsten Patric},
  title     = {Antrag auf L{\"o}schung von Insolvenzvermerken bei Insolvenz eines GbR-Gesellschafters},
  series = {Fachdienst Zivilrecht - LMK - Kommentierte BGH-Rechtsprechung, Lindenmaier-M{\"o}hring},
  journal   = {Fachdienst Zivilrecht - LMK - Kommentierte BGH-Rechtsprechung, Lindenmaier-M{\"o}hring},
  issn      = {1611-1095},
  year      = {2018},
  language  = {de}
}
@inproceedings{LudowicyRingsFingeretal.2018,
  author    = {Ludowicy, Jonas and Rings, Ren{\´e} and Finger, Felix and Braun, Carsten},
  title     = {Sizing Studies of Light Aircraft with Serial Hybrid Propulsion Systems},
  series = {Luft- und Raumfahrt - Digitalisierung und Vernetzung : Deutscher Luft- und Raumfahrtkongress 2018. 4. - 6. September 2018 - Friedrichshafen},
  booktitle = {Luft- und Raumfahrt - Digitalisierung und Vernetzung : Deutscher Luft- und Raumfahrtkongress 2018. 4. - 6. September 2018 - Friedrichshafen},
  pages     = {11 S.},
  year      = {2018},
  language  = {en}
}
@inproceedings{LudowicyRingsFingeretal.2018,
  author    = {Ludowicy, Jonas and Rings, Ren{\´e} and Finger, Felix and Braun, Carsten},
  title     = {Sizing Studies of Light Aircraft with Parallel Hybrid Propulsion Systems},
  series = {Deutscher Luft- und Raumfahrtkongress 2018},
  booktitle = {Deutscher Luft- und Raumfahrtkongress 2018},
  doi       = {10.25967/480227},
  pages     = {15 S.},
  year      = {2018},
  language  = {en}
}
@inproceedings{MarinkovicButenweg2018,
  author    = {Marinkovic, Marko and Butenweg, Christoph},
  title     = {Innovative System for Earthquake Resistant Masonry Infill Walls},
  series = {16th European Conference on Earthquake Engineering, Thessaloniki, 18-21 June, 2018},
  booktitle = {16th European Conference on Earthquake Engineering, Thessaloniki, 18-21 June, 2018},
  pages     = {1 -- 12},
  year      = {2018},
  language  = {en}
}
@article{MatchaLjubasGueldemet2018,
  author    = {Matcha, Heike and Ljubas, Ante and Gueldemet, Harun},
  title     = {Printing a Coffee Bar: An investigation into mid-scale 3D printing},
  series = {Computing for a better tomorrow - Proceedings of the 36th eCAADe Conference - Volume 2, Lodz University of Technology, Lodz, Poland, 19-21 September 2018},
  journal   = {Computing for a better tomorrow - Proceedings of the 36th eCAADe Conference - Volume 2, Lodz University of Technology, Lodz, Poland, 19-21 September 2018},
  editor    = {Kepczynska-Walczak, A.},
  pages     = {59 -- 68},
  year      = {2018},
  abstract  = {We present and discuss an exploration of the possibilities and properties of 3D printing with a printing space of 1 cubic meter, and how those can be integrated into architectural education through an experimental design and research course with students of architecture.We expand on issues presented at the eCAADe conference 2017 in Rome [Ref 6] by increasing the complexity and size of our prints, printing not a model to scale, but a full scale funtional prototype of a usable architectural object: A coffee bar.},
  language  = {en}
}
@article{MichauxMatternKallweit2018,
  author    = {Michaux, F. and Mattern, P. and Kallweit, Stephan},
  title     = {RoboPIV: how robotics enable PIV on a large industrial scale},
  series = {Measurement Science and Technology},
  volume    = {29},
  journal   = {Measurement Science and Technology},
  number    = {7},
  publisher = {IOP},
  address   = {Bristol},
  issn      = {1361-6501},
  doi       = {10.1088/1361-6501/aab5c1},
  pages     = {074009},
  year      = {2018},
  abstract  = {This work demonstrates how the interaction between particle image velocimetry (PIV) and robotics can massively increase measurement efficiency. The interdisciplinary approach is shown using the complex example of an automated, large scale, industrial environment: a typical automotive wind tunnel application. Both the high degree of flexibility in choosing the measurement region and the complete automation of stereo PIV measurements are presented. The setup consists of a combination of three robots, individually used as a 6D traversing unit for the laser illumination system as well as for each of the two cameras. Synchronised movements in the same reference frame are realised through a master-slave setup with a single interface to the user. By integrating the interface into the standard wind tunnel management system, a single measurement plane or a predefined sequence of several planes can be requested through a single trigger event, providing the resulting vector fields within minutes. In this paper, a brief overview on the demands of large scale industrial PIV and the existing solutions is given. Afterwards, the concept of RoboPIV is introduced as a new approach. In a first step, the usability of a selection of commercially available robot arms is analysed. The challenges of pose uncertainty and importance of absolute accuracy are demonstrated through comparative measurements, explaining the individual pros and cons of the analysed systems. Subsequently, the advantage of integrating RoboPIV directly into the existing wind tunnel management system is shown on basis of a typical measurement sequence. In a final step, a practical measurement procedure, including post-processing, is given by using real data and results. Ultimately, the benefits of high automation are demonstrated, leading to a drastic reduction in necessary measurement time compared to non-automated systems, thus massively increasing the efficiency of PIV measurements.},
  language  = {en}
}
@article{MichelButenwegKinkel2018,
  author    = {Michel, Philipp and Butenweg, Christoph and Kinkel, Sven},
  title     = {Pile-grid foundations of onshore wind turbines considering soil-structure-interaction under seismic loading},
  series = {Soil Dynamics and Earthquake Engineering},
  volume    = {109},
  journal   = {Soil Dynamics and Earthquake Engineering},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0267-7261},
  doi       = {10.1016/j.soildyn.2018.03.009},
  pages     = {299 -- 311},
  year      = {2018},
  abstract  = {In recent years, many onshore wind turbines are erected in seismic active regions and on soils with poor load bearing capacity, where pile grids are inevitable to transfer the loads into the ground. In this contribution, a realistic multi pile grid is designed to analyze the dynamics of a wind turbine tower including frequency dependent soil-structure-interaction. It turns out that different foundations on varying soil configurations heavily influence the vibration response. While the vibration amplitude is mostly attenuated, certain unfavorable combinations of structure and soil parameters lead to amplification in the range of the system's natural frequencies. This testifies the need for overall dynamic analysis in the assessment of the dynamic stability and the holistic frequency tuning of the turbines.},
  language  = {en}
}
@inproceedings{MichelButenwegKlinkel2018,
  author    = {Michel, Philipp and Butenweg, Christoph and Klinkel, Sven},
  title     = {Frequency Dependent Impedance Analysis of the Foundation-Soil-Systems of Onshore Wind Turbines},
  series = {16th European Conference on Earthquake Engineering, Thessaloniki, 18-21 June, 2018},
  booktitle = {16th European Conference on Earthquake Engineering, Thessaloniki, 18-21 June, 2018},
  pages     = {1 -- 13},
  year      = {2018},
  language  = {en}
}
@inproceedings{MilkovaRosinButenwegetal.2018,
  author    = {Milkova, Kristina and Rosin, Julia and Butenweg, Christoph and Dumova-Jovanoska, Elena},
  title     = {Development of Seismic Vulnerability Curves for Region Specific Masonry Buildings},
  series = {16th European Conference on Earthquake Engineering, Thessaloniki, 18-21 June, 2018},
  booktitle = {16th European Conference on Earthquake Engineering, Thessaloniki, 18-21 June, 2018},
  pages     = {1 -- 10},
  year      = {2018},
  language  = {en}
}
@article{MiyamotoSekiSutoetal.2018,
  author    = {Miyamoto, Koichiro and Seki, Kosuke and Suto, Takeyuki and Werner, Frederik and Wagner, Torsten and Sch{\"o}ning, Michael Josef and Yoshinobu, Tatsuo},
  title     = {Improved spatial resolution of the chemical imaging sensor with a hybrid illumination that suppresses lateral diffusion of photocarriers},
  series = {Sensor and Actuators B: Chemical},
  volume    = {273},
  journal   = {Sensor and Actuators B: Chemical},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0925-4005},
  doi       = {10.1016/j.snb.2018.07.016},
  pages     = {1328 -- 1333},
  year      = {2018},
  abstract  = {The chemical imaging sensor is a semiconductor-based chemical sensor capable of visualizing pH and ion distributions. The spatial resolution depends on the lateral diffusion of photocarriers generated by illumination of the semiconductor substrate. In this study, two types of optical setups, one based on a bundle of optical fibers and the other based on a binocular tube head, were developed to project a hybrid illumination of a modulated light beam and a ring-shaped constant illumination onto the sensor plate. An improved spatial resolution was realized by the ring-shaped constant illumination, which suppressed lateral diffusion of photocarriers by enhanced recombination due to the increased carrier concentration.},
  language  = {en}
}
@book{Molinnus2018,
  author    = {Molinnus, Denise},
  title     = {Integration of biomolecular logic principles with electronic transducers on a chip},
  publisher = {Philipps-Universit{\"a}t / Fachbereich Pharmazie},
  address   = {Marburg/Lahn},
  year      = {2018},
  language  = {de}
}
@article{MolinnusHardtKaeveretal.2018,
  author    = {Molinnus, Denise and Hardt, G. and K{\"a}ver, L. and Willenberg, H.S. and Kr{\"o}ger, J.-C. and Poghossian, Arshak and Keusgen, Michael and Sch{\"o}ning, Michael Josef},
  title     = {Chip-based biosensor for the detection of low adrenaline concentrations to support adrenal venous sampling},
  series = {Sensor and Actuators B: Chemical},
  volume    = {272},
  journal   = {Sensor and Actuators B: Chemical},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0925-4005},
  doi       = {10.1016/j.snb.2018.05.136},
  pages     = {21 -- 27},
  year      = {2018},
  abstract  = {A chip-based amperometric biosensor referring on using the bioelectrocatalytical amplification principle for the detection of low adrenaline concentrations is presented. The adrenaline biosensor has been prepared by modification of a platinum thin-film electrode with an enzyme membrane containing the pyrroloquinoline quinone-dependent glucose dehydrogenase and glutaraldehyde. Measuring conditions such as temperature, pH value, and glucose concentration have been optimized to achieve a high sensitivity and a low detection limit of about 1 nM adrenaline measured in phosphate buffer at neutral pH value. The response of the biosensor to different catecholamines has also been proven. Long-term stability of the adrenaline biosensor has been studied over 10 days. In addition, the biosensor has been successfully applied for adrenaline detection in human blood plasma for future biomedical applications. Furthermore, preliminary experiments have been carried to detect the adrenaline-concentration difference measured in peripheral blood and adrenal venous blood, representing the adrenal vein sampling procedure of a physician.},
  language  = {en}
}
@article{MolinnusHardtSiegertetal.2018,
  author    = {Molinnus, Denise and Hardt, Gabriel and Siegert, Petra and Willenberg, Holger S. and Poghossian, Arshak and Keusgen, Michael and Sch{\"o}ning, Michael Josef},
  title     = {Detection of Adrenaline in Blood Plasma as Biomarker for Adrenal Venous Sampling},
  series = {Electroanalysis},
  volume    = {30},
  journal   = {Electroanalysis},
  number    = {5},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {1521-4109},
  doi       = {10.1002/elan.201800026},
  pages     = {937 -- 942},
  year      = {2018},
  abstract  = {An amperometric bi-enzyme biosensor based on substrate recycling principle for the amplification of the sensor signal has been developed for the detection of adrenaline in blood. Adrenaline can be used as biomarker verifying successful adrenal venous sampling procedure. The adrenaline biosensor has been realized via modification of a galvanic oxygen sensor with a bi-enzyme membrane combining a genetically modified laccase and a pyrroloquinoline quinone-dependent glucose dehydrogenase. The measurement conditions such as pH value and temperature were optimized to enhance the sensor performance. A high sensitivity and a low detection limit of about 0.5-1 nM adrenaline have been achieved in phosphate buffer at pH 7.4, relevant for measurements in blood samples. The sensitivity of the biosensor to other catecholamines such as noradrenaline, dopamine and dobutamine has been studied. Finally, the sensor has been successfully applied for the detection of adrenaline in human blood plasma.},
  language  = {en}
}
@article{MolinnusMuschallikGonzalezetal.2018,
  author    = {Molinnus, Denise and Muschallik, Lukas and Gonzalez, Laura Osorio and Bongaerts, Johannes and Wagner, Torsten and Selmer, Thorsten and Siegert, Petra and Keusgen, Michael and Sch{\"o}ning, Michael Josef},
  title     = {Development and characterization of a field-effect biosensor for the detection of acetoin},
  series = {Biosensors and Bioelectronics},
  volume    = {115},
  journal   = {Biosensors and Bioelectronics},
  publisher = {Elsevier},
  address   = {Amsterdam},
  doi       = {10.1016/j.bios.2018.05.023},
  pages     = {1 -- 6},
  year      = {2018},
  abstract  = {A capacitive electrolyte-insulator-semiconductor (EIS) field-effect biosensor for acetoin detection has been presented for the first time. The EIS sensor consists of a layer structure of Al/p-Si/SiO₂/Ta₂O₅/enzyme acetoin reductase. The enzyme, also referred to as butane-2,3-diol dehydrogenase from B. clausii DSM 8716T, has been recently characterized. The enzyme catalyzes the (R)-specific reduction of racemic acetoin to (R,R)- and meso-butane-2,3-diol, respectively. Two different enzyme immobilization strategies (cross-linking by using glutaraldehyde and adsorption) have been studied. Typical biosensor parameters such as optimal pH working range, sensitivity, hysteresis, linear concentration range and long-term stability have been examined by means of constant-capacitance (ConCap) mode measurements. Furthermore, preliminary experiments have been successfully carried out for the detection of acetoin in diluted white wine samples.},
  language  = {en}
}
@article{MuellerBeckersMussmannetal.2018,
  author    = {M{\"u}ller, Janina and Beckers, Mario and Mußmann, Nina and Bongaerts, Johannes and B{\"u}chs, Jochen},
  title     = {Elucidation of auxotrophic deficiencies of Bacillus pumilus DSM 18097 to develop a defined minimal medium},
  series = {Microbial Cell Factories},
  volume    = {17},
  journal   = {Microbial Cell Factories},
  number    = {1},
  publisher = {BioMed Central},
  issn      = {1475-2859},
  doi       = {10.1186/s12934-018-0956-1},
  pages     = {Article No. 106},
  year      = {2018},
  abstract  = {Background Culture media containing complex compounds like yeast extract or peptone show numerous disadvantages. The chemical composition of the complex compounds is prone to significant variations from batch to batch and quality control is difficult. Therefore, the use of chemically defined media receives more and more attention in commercial fermentations. This concept results in better reproducibility, it simplifies downstream processing of secreted products and enable rapid scale-up. Culturing bacteria with unknown auxotrophies in chemically defined media is challenging and often not possible without an extensive trial-and-error approach. In this study, a respiration activity monitoring system for shake flasks and its recent version for microtiter plates were used to clarify unknown auxotrophic deficiencies in the model organism Bacillus pumilus DSM 18097. Results Bacillus pumilus DSM 18097 was unable to grow in a mineral medium without the addition of complex compounds. Therefore, a rich chemically defined minimal medium was tested containing basically all vitamins, amino acids and nucleobases, which are essential ingredients of complex components. The strain was successfully cultivated in this medium. By monitoring of the respiration activity, nutrients were supplemented to and omitted from the rich chemically defined medium in a rational way, thus enabling a systematic and fast determination of the auxotrophic deficiencies. Experiments have shown that the investigated strain requires amino acids, especially cysteine or histidine and the vitamin biotin for growth. Conclusions The introduced method allows an efficient and rapid identification of unknown auxotrophic deficiencies and can be used to develop a simple chemically defined tailor-made medium. B. pumilus DSM 18097 was chosen as a model organism to demonstrate the method. However, the method is generally suitable for a wide range of microorganisms. By combining a systematic combinatorial approach based on monitoring the respiration activity with cultivation in microtiter plates, high throughput experiments with high information content can be conducted. This approach facilitates media development, strain characterization and cultivation of fastidious microorganisms in chemically defined minimal media while simultaneously reducing the experimental effort.},
  language  = {en}
}
@incollection{MuellerAltherrAholaetal.2018,
  author    = {M{\"u}ller, Tim M. and Altherr, Lena and Ahola, Marja and Schabel, Samuel and Pelz, Peter F.},
  title     = {Optimizing pressure screen systems in paper recycling: optimal system layout, component selection and operation},
  publisher = {Springer},
  address   = {Cham},
  isbn      = {978-3-030-18499-5},
  doi       = {10.1007/978-3-030-18500-8_44},
  pages     = {355 -- 361},
  year      = {2018},
  abstract  = {Around 60\% of the paper worldwide is made from recovered paper. Especially adhesive contaminants, so called stickies, reduce paper quality. To remove stickies but at the same time keep as many valuable fibers as possible, multi-stage screening systems with several interconnected pressure screens are used. When planning such systems, suitable screens have to be selected and their interconnection as well as operational parameters have to be defined considering multiple conflicting objectives. In this contribution, we present a Mixed-Integer Nonlinear Program to optimize system layout, component selection and operation to find a suitable trade-off between output quality and yield.},
  language  = {en}
}
@inproceedings{MuellerAbdelrazeqBraunerCaleroValdezetal.2018,
  author    = {M{\"u}ller-Abdelrazeq, Sarah Luisa and Brauner, Philipp and Calero Valdez, Andr{\´e} and Jansen, Ulrich and Platte, Laura and Schaar, Anne-Kathrin and Steuer-Dankert, Linda and Zachow, Sebastian and Sch{\"o}nefeld, Kathrin and Haberstroh, Max and Leicht-Scholten, Carmen and Ziefle, Martina},
  title     = {Interdisciplinary cooperation management in research clusters: a review of twelve years.},
  series = {Proceedings of the 15th International Conference on Intellectual Capital, Knowledge Management \& Organisational Learning},
  booktitle = {Proceedings of the 15th International Conference on Intellectual Capital, Knowledge Management \& Organisational Learning},
  editor    = {Pather, Shaun},
  publisher = {ACPIL},
  isbn      = {978-1-912764-09-9},
  pages     = {216 -- 224},
  year      = {2018},
  abstract  = {As an interdisciplinary research network, the Cluster of Excellence "Integrative Production Technology for High-Wage Countries" (CoE) comprises of around 150 researchers. Their scientific background ranges from mechanical engineering and computer science to social sciences such as sociology and psychology. In addition to content- and methodbased challenges, the CoE's employees are faced with heterogenic organizational cultures, different hierarchical levels, an imbalanced gender distribution, and a high employee fluctuation. The sub-project Scientific Cooperation Engineering 1 (CSP1) addresses the challenge of interdisciplinary cooperation and organizational learning and aims at fostering interdisciplinarity and its synergies as a source of innovation. Therefore, the project examines means of reaching an organizational development, ranging from temporal structures to a sustainable network in production technology. To achieve this aim, a broad range of means has been developed during the last twelve years: In addition to physical measures such as regular network events and trainings, virtual measures such as the Terminology App were focused. The app is an algorithmic analysis method for uncovering latent topic structures of publications of the CoE to highlight thematic intersections and synergy potentials. The detection and promotion of has been a vital and long known element in knowledge management. Furthermore, CSP1 focusses on project management and thus developed evaluation tools to measure and control the success of interdisciplinary cooperation. In addition to the cooperation fostering measures, CSP1 conducted studies about interdisciplinarity and diversity and their relationship with innovation. The scientific background of these means and the research results of CSP1 are outlined in this paper to offer approaches for successful interdisciplinary cooperation management.},
  language  = {en}
}
@article{OberlaenderMayerGreeffetal.2018,
  author    = {Oberl{\"a}nder, Jan and Mayer, Marlena and Greeff, Anton and Keusgen, Michael and Sch{\"o}ning, Michael Josef},
  title     = {Spore-based biosensor to monitor the microbicidal efficacy of gaseous hydrogen peroxide sterilization processes},
  series = {Biosensors and Bioelectronics},
  volume    = {104},
  journal   = {Biosensors and Bioelectronics},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0956-5663},
  doi       = {10.1016/j.bios.2017.12.045},
  pages     = {87 -- 94},
  year      = {2018},
  abstract  = {In this work, a spore-based biosensor is evaluated to monitor the microbicidal efficacy of sterilization processes applying gaseous hydrogen peroxide (H2O2). The sensor is based on interdigitated electrode structures (IDEs) that have been fabricated by means of thin-film technologies. Impedimetric measurements are applied to study the effect of sterilization process on spores of Bacillus atrophaeus. This resilient microorganism is commonly used in industry to proof the sterilization efficiency. The sensor measurements are accompanied by conventional microbiological challenge tests, as well as morphological characterizations with scanning electron microscopy (SEM) and transmission electron microscopy (TEM). The sensor measurements are correlated with the microbiological test routines. In both methods, namely the sensor-based and microbiological one, a tailing effect has been observed. The results are evaluated and discussed in a three-dimensional calibration plot demonstrating the sensor's suitability to enable a rapid process decision in terms of a successfully performed sterilization.},
  language  = {en}
}
@article{Olbertz2018,
  author    = {Olbertz, Klaus},
  title     = {{\"U}berwachung von Arbeitnehmern als Ausdruck von Compliance - Grunds{\"a}tze sowie Zul{\"a}ssigkeit und Grenzen einzelner Maßnahmen},
  series = {NWB - Steuer- und Wirtschaftsrecht},
  journal   = {NWB - Steuer- und Wirtschaftsrecht},
  number    = {21},
  publisher = {NWB-Verl.},
  address   = {Herne},
  issn      = {1860-9449},
  pages     = {1547 -- 1555},
  year      = {2018},
  language  = {de}
}
@article{Olbertz2018,
  author    = {Olbertz, Klaus},
  title     = {Das rechtssichere Arbeitszeugnis - Erlaubte und nicht erlaubte Formulierungen und anderes Wissenswertes},
  series = {NWB - Steuer- und Wirtschaftsrecht},
  journal   = {NWB - Steuer- und Wirtschaftsrecht},
  number    = {12},
  publisher = {NWB-Verl.},
  address   = {Herne},
  issn      = {1860-9449},
  pages     = {802 -- 813},
  year      = {2018},
  language  = {de}
}
@article{Olbertz2018,
  author    = {Olbertz, Klaus},
  title     = {Der Interimsmanager als Selbst{\"a}ndiger oder Arbeitnehmer : Vertragliche Varianten des Interimsmanagements im Faktencheck},
  series = {NWB - Steuer- und Wirtschaftsrecht},
  journal   = {NWB - Steuer- und Wirtschaftsrecht},
  number    = {31},
  publisher = {NWB-Verl.},
  address   = {Herne},
  issn      = {1860-9449},
  pages     = {2260 -- 2266},
  year      = {2018},
  language  = {de}
}
@article{Olbertz2018,
  author    = {Olbertz, Klaus},
  title     = {Bindung des Betriebserwerbers an zuk{\"u}nftige Tariflohnerh{\"o}hungen : Auswirkungen eines Betriebs{\"u}bergangs auf Bezugnahmeklauseln in {\"u}bernommenen Arbeitsvertr{\"a}gen},
  series = {NWB - Steuer- und Wirtschaftsrecht},
  journal   = {NWB - Steuer- und Wirtschaftsrecht},
  number    = {39},
  publisher = {NWB-Verl.},
  address   = {Herne},
  issn      = {1860-9449},
  pages     = {2864 -- 2869},
  year      = {2018},
  language  = {de}
}
@article{OttenWeberArent2018,
  author    = {Otten, Dennis and Weber, Tobias and Arent, Jan-Christoph},
  title     = {Manufacturing Process Simulation - On Its Way to Industrial Application},
  series = {International Journal of Aviation, Aeronautics, and Aerospace},
  volume    = {5},
  journal   = {International Journal of Aviation, Aeronautics, and Aerospace},
  number    = {2},
  publisher = {Embry-Riddle Aeronautical University},
  address   = {Daytona Beach, Fla.},
  issn      = {2374-6793},
  doi       = {10.15394/ijaaa.2018.1217},
  year      = {2018},
  abstract  = {Manufacturing process simulation (MPS) has become more and more important for aviation and the automobile industry. A highly competitive market requires the use of high performance metals and composite materials in combination with reduced manufacturing cost and time as well as a minimization of the time to market for a new product. However, the use of such materials is expensive and requires sophisticated manufacturing processes. An experience based process and tooling design followed by a lengthy trial-and-error optimization is just not contemporary anymore. Instead, a tooling design process aided by simulation is used more often. This paper provides an overview of the capabilities of MPS in the fields of sheet metal forming and prepreg autoclave manufacturing of composite parts summarizing the resulting benefits for tooling design and manufacturing engineering. The simulation technology is explained briefly in order to show several simplification and optimization techniques for developing industrialized simulation approaches. Small case studies provide examples of an efficient application on an industrial scale.},
  language  = {en}
}
@inproceedings{Pfaff2018,
  author    = {Pfaff, Raphael},
  title     = {Railway Challenge 2018 - Ein Wettbewerb f{\"u}r Parkbahn-Lokomotiven},
  series = {Deine Bahn},
  booktitle = {Deine Bahn},
  issn      = {0948-7263},
  pages     = {22 -- 24},
  year      = {2018},
  language  = {de}
}
@inproceedings{PfaffMelcherFranzen2018,
  author    = {Pfaff, Raphael and Melcher, Karin and Franzen, Julian},
  title     = {Rare event simulation to optimise maintenance intervals of safety critical redundant subsystems},
  series = {Proceedings of the European Conference of the PHM Society},
  volume    = {4},
  booktitle = {Proceedings of the European Conference of the PHM Society},
  number    = {1},
  pages     = {1 -- 6},
  year      = {2018},
  language  = {en}
}
@incollection{PielenRoethFlatten2018,
  author    = {Pielen, Michael and R{\"o}th, Thilo and Flatten, T.},
  title     = {Erfolgsfaktoren k{\"u}nftiger Gesch{\"a}ftsmodelle von urbanen, geteilten Mobilit{\"a}tsdienstleistungen},
  series = {Mobilit{\"a}t und digitale Transformation. (9. Wissenschaftsforum Mobilit{\"a}t. Tagungsband)},
  booktitle = {Mobilit{\"a}t und digitale Transformation. (9. Wissenschaftsforum Mobilit{\"a}t. Tagungsband)},
  editor    = {Proff, H.},
  publisher = {Springer Gabler},
  address   = {Wiesbaden},
  isbn      = {978-3-658-20779-3},
  doi       = {10.1007/978-3-658-20779-3_2},
  pages     = {435 -- 448},
  year      = {2018},
  abstract  = {Digitalisierung bezeichnet die Nutzung großer Datenmengen, die zu einer umfassenden Vernetzung aller Bereiche der Wirtschaft und Gesellschaft f{\"u}hren wird (BMWi, 2015 und {\"a}hnlich K{\"o}hler/Wollschl{\"a}ger, 2014: 79). Sie umfasst die Erhebung von analogen Informationen („Big Data" in einem engen Sinne; z.B. O´Leary, 2013), ihre Speicherung in einem digitaltechnischen System (lokale Speicherung oder „Cloud Computing" durch die Weiterentwickelung des Internets; z.B. Hashem et al., 2015: 101), die Analyse und Interpretation sowie den Transfer in andere Systeme („Internet der Dinge" bzw. „Internet of Things"; z.B. Ashton, 2009).},
  language  = {de}
}
@inproceedings{Pieper2018,
  author    = {Pieper, Martin},
  title     = {Digitale Hochschullehre in mathematischen und mathematikdidaktischen Veranstaltungen},
  series = {Beitr{\"a}ge zum Mathematikunterricht 2018 : Vortr{\"a}ge zur Mathematikdidaktik und zur Schnittstelle Mathematik/Mathematikdidaktik auf der gemeinsamen Jahrestagung GDM und DMV 2018 (52. Jahrestagung der Gesellschaft f{\"u}r Didaktik der Mathematik). Bd. 1},
  booktitle = {Beitr{\"a}ge zum Mathematikunterricht 2018 : Vortr{\"a}ge zur Mathematikdidaktik und zur Schnittstelle Mathematik/Mathematikdidaktik auf der gemeinsamen Jahrestagung GDM und DMV 2018 (52. Jahrestagung der Gesellschaft f{\"u}r Didaktik der Mathematik). Bd. 1},
  publisher = {WTM-Verlag},
  address   = {M{\"u}nster},
  isbn      = {978-3-95987-089-4},
  pages     = {105 -- 106},
  year      = {2018},
  language  = {de}
}
@inproceedings{Pieper2018,
  author    = {Pieper, Martin},
  title     = {Lernzielorientierte Kurse und Stack Aufgaben in der Mathematikausbildung},
  series = {Beitr{\"a}ge zum Mathematikunterricht 2018 : Vortr{\"a}ge zur Mathematikdidaktik und zur Schnittstelle Mathematik/Mathematikdidaktik auf der gemeinsamen Jahrestagung GDM und DMV 2018 (52. Jahrestagung der Gesellschaft f{\"u}r Didaktik der Mathematik). Bd. 3},
  booktitle = {Beitr{\"a}ge zum Mathematikunterricht 2018 : Vortr{\"a}ge zur Mathematikdidaktik und zur Schnittstelle Mathematik/Mathematikdidaktik auf der gemeinsamen Jahrestagung GDM und DMV 2018 (52. Jahrestagung der Gesellschaft f{\"u}r Didaktik der Mathematik). Bd. 3},
  publisher = {WTM-Verlag},
  address   = {M{\"u}nster},
  isbn      = {978-3-95987-089-4},
  pages     = {1399 -- 1402},
  year      = {2018},
  language  = {de}
}
@article{PilasYaziciSelmeretal.2018,
  author    = {Pilas, Johanna and Yazici, Y. and Selmer, Thorsten and Keusgen, M. and Sch{\"o}ning, Michael Josef},
  title     = {Application of a portable multi-analyte biosensor for organic acid determination in silage},
  series = {Sensors},
  volume    = {18},
  journal   = {Sensors},
  number    = {5},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {1424-8220},
  doi       = {10.3390/s18051470},
  pages     = {12 Seiten},
  year      = {2018},
  abstract  = {Multi-analyte biosensors may offer the opportunity to perform cost-effective and rapid analysis with reduced sample volume, as compared to electrochemical biosensing of each analyte individually. This work describes the development of an enzyme-based biosensor system for multi-parametric determination of four different organic acids. The biosensor array comprises five working electrodes for simultaneous sensing of ethanol, formate, d-lactate, and l-lactate, and an integrated counter electrode. Storage stability of the biosensor was evaluated under different conditions (stored at +4 °C in buffer solution and dry at -21 °C, +4 °C, and room temperature) over a period of 140 days. After repeated and regular application, the individual sensing electrodes exhibited the best stability when stored at -21 °C. Furthermore, measurements in silage samples (maize and sugarcane silage) were conducted with the portable biosensor system. Comparison with a conventional photometric technique demonstrated successful employment for rapid monitoring of complex media.},
  language  = {en}
}
@article{PoghossianJablonskiKochetal.2018,
  author    = {Poghossian, Arshak and Jablonski, Melanie and Koch, Claudia and Bronder, Thomas and Rolka, David and Wege, Christina and Sch{\"o}ning, Michael Josef},
  title     = {Field-effect biosensor using virus particles as scaffolds for enzyme immobilization},
  series = {Biosensors and Bioelectronics},
  volume    = {110},
  journal   = {Biosensors and Bioelectronics},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0956-5663},
  doi       = {10.1016/j.bios.2018.03.036},
  pages     = {168 -- 174},
  year      = {2018},
  abstract  = {A field-effect biosensor employing tobacco mosaic virus (TMV) particles as scaffolds for enzyme immobilization is presented. Nanotubular TMV scaffolds allow a dense immobilization of precisely positioned enzymes with retained activity. To demonstrate feasibility of this new strategy, a penicillin sensor has been developed by coupling a penicillinase with virus particles as a model system. The developed field-effect penicillin biosensor consists of an Al-p-Si-SiO₂-Ta₂O₅-TMV structure and has been electrochemically characterized in buffer solutions containing different concentrations of penicillin G. In addition, the morphology of the biosensor surface with virus particles was characterized by scanning electron microscopy and atomic force microscopy methods. The sensors possessed a high penicillin sensitivity of ~ 92 mV/dec in a nearly-linear range from 0.1 mM to 10 mM, and a low detection limit of about 50 µM. The long-term stability of the penicillin biosensor was periodically tested over a time period of about one year without any significant loss of sensitivity. The biosensor has also been successfully applied for penicillin detection in bovine milk samples.},
  language  = {en}
}
@article{PuppeGiulianoFrantzetal.2018,
  author    = {Puppe, Michael and Giuliano, Stefano and Frantz, Cathy and Uhlig, Ralf and Schumacher, Ralph and Ibraheem, Wagdi and Schmalz, Stefan and Waldmann, Barbara and Guder, Christoph and Peter, Dennis and Schwager, Christian and Teixeira Boura, Cristiano Jos{\´e} and Alexopoulos, Spiros and Spiegel, Michael and Wortmann, J{\"u}rgen and Hinrichs, Matthias and Engelhard, Manfred and Aust, Michael},
  title     = {Techno-economic optimization of molten salt solar tower plants},
  series = {AIP Conference Proceedings art.no. 040033},
  volume    = {2033},
  journal   = {AIP Conference Proceedings art.no. 040033},
  number    = {Issue 1},
  publisher = {AIP Publishing},
  address   = {Melville, NY},
  doi       = {10.1063/1.5067069},
  year      = {2018},
  abstract  = {In this paper the results of a techno-economic analysis of improved and optimized molten salt solar tower plants (MSSTP plants) are presented. The potential improvements that were analyzed include different receiver designs, different designs of the HTF-system and plant control, increased molten salt temperatures (up to 640°C) and multi-tower systems. Detailed technological and economic models of the solar field, solar receiver and high temperature fluid system (HTF-system) were developed and used to find potential improvements compared to a reference plant based on Solar Two technology and up-to-date cost estimations. The annual yield model calculates the annual outputs and the LCOE of all variants. An improved external tubular receiver and improved HTF-system achieves a significant decrease of LCOE compared to the reference. This is caused by lower receiver cost as well as improvements of the HTF-system and plant operation strategy, significantly reducing the plant own consumption. A novel star receiver shows potential for further cost decrease. The cavity receiver concepts result in higher LCOE due to their high investment cost, despite achieving higher efficiencies. Increased molten salt temperatures seem possible with an adapted, closed loop HTF-system and achieve comparable results to the original improved system (with 565°C) under the given boundary conditions. In this analysis all multi tower systems show lower economic viability compared to single tower systems, caused by high additional cost for piping connections and higher cost of the receivers. REFERENCES},
  language  = {en}
}
@article{QuittmannMeskemperAbeletal.2018,
  author    = {Quittmann, Oliver J. and Meskemper, Joshua and Abel, Thomas and Albracht, Kirsten and Foitschik, Tina and Rojas-Vega, Sandra and Str{\"u}der, Heiko K.},
  title     = {Kinematics and kinetics of handcycling propulsion at increasing workloads in able-bodied subjects},
  series = {Sports Engineereing},
  volume    = {21},
  journal   = {Sports Engineereing},
  number    = {21},
  publisher = {Springer Nature},
  address   = {Cham},
  issn      = {1460-2687},
  doi       = {10.1007/s12283-018-0269-y},
  pages     = {283 -- 294},
  year      = {2018},
  abstract  = {In Paralympic sports, biomechanical optimisation of movements and equipment seems to be promising for improving performance. In handcycling, information about the biomechanics of this sport is mainly provided by case studies. The aim of the current study was (1) to examine changes in handcycling propulsion kinematics and kinetics due to increasing workloads and (2) identify parameters that are associated with peak aerobic performance. Twelve non-disabled male competitive triathletes without handcycling experience voluntarily participated in the study. They performed an initial familiarisation protocol and incremental step test until exhaustion in a recumbent racing handcycle that was attached to an ergometer. During the incremental test, tangential crank kinetics, 3D joint kinematics, blood lactate and ratings of perceived exertion (local and global) were identified. As a performance criterion, the maximal power output during the step test (Pmax) was calculated and correlated with biomechanical parameters. For higher workloads, an increase in crank torque was observed that was even more pronounced in the pull phase than in the push phase. Furthermore, participants showed an increase in shoulder internal rotation and abduction and a decrease in elbow flexion and retroversion. These changes were negatively correlated with performance. At high workloads, it seems that power output is more limited by the transition from pull to push phase than at low workloads. It is suggested that successful athletes demonstrate small alterations of their kinematic profile due to increasing workloads. Future studies should replicate and expand the test spectrum (sprint and continuous loads) as well as use methods like surface electromyography (sEMG) with elite handcyclists.},
  language  = {de}
}
@article{RabehiGarlanAchtsnichtetal.2018,
  author    = {Rabehi, Amine and Garlan, Benjamin and Achtsnicht, Stefan and Krause, Hans-Joachim and Offenh{\"a}usser, Andreas and Ngo, Kieu and Neveu, Sophie and Graff-Dubois, Stephanie and Kokabi, Hamid},
  title     = {Magnetic detection structure for Lab-on-Chip applications based on the frequency mixing technique},
  series = {Sensors},
  volume    = {18},
  journal   = {Sensors},
  number    = {6},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {1424-8220},
  doi       = {10.3390/s18061747},
  pages     = {14 Seiten},
  year      = {2018},
  abstract  = {A magnetic frequency mixing technique with a set of miniaturized planar coils was investigated for use with a completely integrated Lab-on-Chip (LoC) pathogen sensing system. The system allows the detection and quantification of superparamagnetic beads. Additionally, in terms of magnetic nanoparticle characterization ability, the system can be used for immunoassays using the beads as markers. Analytical calculations and simulations for both excitation and pick-up coils are presented; the goal was to investigate the miniaturization of simple and cost-effective planar spiral coils. Following these calculations, a Printed Circuit Board (PCB) prototype was designed, manufactured, and tested for limit of detection, linear response, and validation of theoretical concepts. Using the magnetic frequency mixing technique, a limit of detection of 15 µg/mL of 20 nm core-sized nanoparticles was achieved without any shielding.},
  language  = {en}
}