@incollection{AltherrDoerigEdereretal.2017, author = {Altherr, Lena and D{\"o}rig, Bastian and Ederer, Thorsten and Pelz, Peter Franz and Pfetsch, Marc and Wolf, Jan}, title = {A mixed-integer nonlinear program for the design of gearboxes}, series = {Operations Research Proceedings 2016}, booktitle = {Operations Research Proceedings 2016}, publisher = {Springer}, address = {Cham}, isbn = {978-3-319-55701-4}, doi = {10.1007/978-3-319-55702-1_31}, pages = {227 -- 233}, year = {2017}, abstract = {Gearboxes are mechanical transmission systems that provide speed and torque conversions from a rotating power source. Being a central element of the drive train, they are relevant for the efficiency and durability of motor vehicles. In this work, we present a new approach for gearbox design: Modeling the design problem as a mixed-integer nonlinear program (MINLP) allows us to create gearbox designs from scratch for arbitrary requirements and—given enough time—to compute provably globally optimal designs for a given objective. We show how different degrees of freedom influence the runtime and present an exemplary solution.}, language = {en} } @inproceedings{AltherrEdererFarnetaneetal.2017, author = {Altherr, Lena and Ederer, Thorsten and Farnetane, Lucas S. and P{\"o}ttgen, Philipp and Verg{\´e}, Angela and Pelz, Peter F.}, title = {Multicriterial design of a hydrostatic transmission system via mixed-integer programming}, series = {Operations Research Proceedings 2015}, booktitle = {Operations Research Proceedings 2015}, publisher = {Springer}, address = {Cham}, isbn = {978-3-319-42901-4}, doi = {10.1007/978-3-319-42902-1_41}, pages = {301 -- 307}, year = {2017}, abstract = {In times of planned obsolescence the demand for sustainability keeps growing. Ideally, a technical system is highly reliable, without failures and down times due to fast wear of single components. At the same time, maintenance should preferably be limited to pre-defined time intervals. Dispersion of load between multiple components can increase a system's reliability and thus its availability inbetween maintenance points. However, this also results in higher investment costs and additional efforts due to higher complexity. Given a specific load profile and resulting wear of components, it is often unclear which system structure is the optimal one. Technical Operations Research (TOR) finds an optimal structure balancing availability and effort. We present our approach by designing a hydrostatic transmission system.}, language = {en} } @incollection{AltherrEdererLorenzetal.2016, author = {Altherr, Lena and Ederer, Thorsten and Lorenz, Ulf and Pelz, Peter F. and P{\"o}ttgen, Philipp}, title = {Designing a feedback control system via mixed-integer programming}, series = {Operations Research Proceedings 2014: Selected Papers of the Annual International Conference of the German Operations Research}, booktitle = {Operations Research Proceedings 2014: Selected Papers of the Annual International Conference of the German Operations Research}, editor = {L{\"u}bbecke, Marco E. and Koster, Arie and Letmathe, Peter and Madlener, Reihard and Preis, Britta and Walther, Grit}, publisher = {Springer}, address = {Cham}, isbn = {978-3-319-28695-2}, doi = {10.1007/978-3-319-28697-6_18}, pages = {121 -- 127}, year = {2016}, abstract = {Pure analytical or experimental methods can only find a control strategy for technical systems with a fixed setup. In former contributions we presented an approach that simultaneously finds the optimal topology and the optimal open-loop control of a system via Mixed Integer Linear Programming (MILP). In order to extend this approach by a closed-loop control we present a Mixed Integer Program for a time discretized tank level control. This model is the basis for an extension by combinatorial decisions and thus for the variation of the network topology. Furthermore, one is able to appraise feasible solutions using the global optimality gap.}, language = {en} } @article{AltherrEdererLorenzetal.2014, author = {Altherr, Lena and Ederer, Thorsten and Lorenz, Ulf and Pelz, Peter F. and P{\"o}ttgen, Philipp}, title = {Experimental validation of an enhanced system synthesis approach}, series = {Operations Research Proceedings 2014}, journal = {Operations Research Proceedings 2014}, editor = {L{\"u}bbecke, Marco and Koster, Arie and Letmathe, Peter and Madlener, Reihard and Peis, Britta and Walther, Grit}, publisher = {Springer}, address = {Basel}, isbn = {978-3-319-28695-2}, doi = {10.1007/978-3-319-28697-6_1}, pages = {6}, year = {2014}, abstract = {Planning the layout and operation of a technical system is a common task for an engineer. Typically, the workflow is divided into consecutive stages: First, the engineer designs the layout of the system, with the help of his experience or of heuristic methods. Secondly, he finds a control strategy which is often optimized by simulation. This usually results in a good operating of an unquestioned sys- tem topology. In contrast, we apply Operations Research (OR) methods to find a cost-optimal solution for both stages simultaneously via mixed integer program- ming (MILP). Technical Operations Research (TOR) allows one to find a provable global optimal solution within the model formulation. However, the modeling error due to the abstraction of physical reality remains unknown. We address this ubiq- uitous problem of OR methods by comparing our computational results with mea- surements in a test rig. For a practical test case we compute a topology and control strategy via MILP and verify that the objectives are met up to a deviation of 8.7\%.}, language = {en} } @article{AltherrEdererPoettgenetal.2015, author = {Altherr, Lena and Ederer, Thorsten and P{\"o}ttgen, Philipp and Lorenz, Ulf and Pelz, Peter F.}, title = {Multicriterial optimization of technical systems considering multiple load and availability scenarios}, series = {Applied Mechanics and Materials}, volume = {807}, journal = {Applied Mechanics and Materials}, editor = {Pelz, Peter F. and Groche, Peter}, isbn = {1660-9336}, doi = {10.4028/www.scientific.net/AMM.807.247}, pages = {247 -- 256}, year = {2015}, abstract = {Cheap does not imply cost-effective -- this is rule number one of zeitgeisty system design. The initial investment accounts only for a small portion of the lifecycle costs of a technical system. In fluid systems, about ninety percent of the total costs are caused by other factors like power consumption and maintenance. With modern optimization methods, it is already possible to plan an optimal technical system considering multiple objectives. In this paper, we focus on an often neglected contribution to the lifecycle costs: downtime costs due to spontaneous failures. Consequently, availability becomes an issue.}, language = {en} } @inproceedings{AltherrEdererSchaenzleetal.2017, author = {Altherr, Lena and Ederer, Thorsten and Sch{\"a}nzle, Christian and Lorenz, Ulf and Pelz, Peter F.}, title = {Algorithmic system design using scaling and affinity laws}, series = {Operations Research Proceedings 2015}, booktitle = {Operations Research Proceedings 2015}, publisher = {Springer}, address = {Cham}, isbn = {978-3-319-42901-4}, doi = {10.1007/978-3-319-42902-1}, pages = {605 -- 611}, year = {2017}, abstract = {Energy-efficient components do not automatically lead to energy-efficient systems. Technical Operations Research (TOR) shifts the focus from the single component to the system as a whole and finds its optimal topology and operating strategy simultaneously. In previous works, we provided a preselected construction kit of suitable components for the algorithm. This approach may give rise to a combinatorial explosion if the preselection cannot be cut down to a reasonable number by human intuition. To reduce the number of discrete decisions, we integrate laws derived from similarity theory into the optimization model. Since the physical characteristics of a production series are similar, it can be described by affinity and scaling laws. Making use of these laws, our construction kit can be modeled more efficiently: Instead of a preselection of components, it now encompasses whole model ranges. This allows us to significantly increase the number of possible set-ups in our model. In this paper, we present how to embed this new formulation into a mixed-integer program and assess the run time via benchmarks. We present our approach on the example of a ventilation system design problem.}, language = {en} } @article{AltherrJoggerstLeiseetal.2018, author = {Altherr, Lena and Joggerst, Laura and Leise, Philipp and Pfetsch, Marc E. and Schmitt, Andreas and Wendt, Janine}, title = {On obligations in the development process of resilient systems with algorithmic design methods}, series = {Applied Mechanics and Materials}, volume = {885}, journal = {Applied Mechanics and Materials}, number = {885}, publisher = {Trans Tech Publications}, address = {B{\"a}ch}, isbn = {1662-7482}, doi = {10.4028/www.scientific.net/AMM.885.240}, pages = {240 -- 252}, year = {2018}, abstract = {Advanced computational methods are needed both for the design of large systems and to compute high accuracy solutions. Such methods are efficient in computation, but the validation of results is very complex, and highly skilled auditors are needed to verify them. We investigate legal questions concerning obligations in the development phase, especially for technical systems developed using advanced methods. In particular, we consider methods of resilient and robust optimization. With these techniques, high performance solutions can be found, despite a high variety of input parameters. However, given the novelty of these methods, it is uncertain whether legal obligations are being met. The aim of this paper is to discuss if and how the choice of a specific computational method affects the developer's product liability. The review of legal obligations in this paper is based on German law and focuses on the requirements that must be met during the design and development process.}, language = {en} } @incollection{AltherrLeise2021, author = {Altherr, Lena and Leise, Philipp}, title = {Resilience as a concept for mastering uncertainty}, series = {Mastering Uncertainty in Mechanical Engineering}, booktitle = {Mastering Uncertainty in Mechanical Engineering}, publisher = {Springer}, address = {Cham}, isbn = {978-3-030-78353-2}, doi = {10.1007/978-3-030-78354-9}, pages = {412 -- 417}, year = {2021}, language = {en} } @article{AltherrLeisePfetschetal.2018, author = {Altherr, Lena and Leise, Philipp and Pfetsch, Marc E. and Schmitt, Andreas}, title = {Algorithmic design and resilience assessment of energy efficient high-rise water supply systems}, series = {Applied Mechanics and Materials}, volume = {885}, journal = {Applied Mechanics and Materials}, publisher = {Trans Tech Publications}, address = {B{\"a}ch}, issn = {1662-7482}, doi = {10.4028/www.scientific.net/AMM.885.211}, pages = {211 -- 223}, year = {2018}, abstract = {High-rise water supply systems provide water flow and suitable pressure in all levels of tall buildings. To design such state-of-the-art systems, the consideration of energy efficiency and the anticipation of component failures are mandatory. In this paper, we use Mixed-Integer Nonlinear Programming to compute an optimal placement of pipes and pumps, as well as an optimal control strategy.Moreover, we consider the resilience of the system to pump failures. A resilient system is able to fulfill a predefined minimum functionality even though components fail or are restricted in their normal usage. We present models to measure and optimize the resilience. To demonstrate our approach, we design and analyze an optimal resilient decentralized water supply system inspired by a real-life hotel building.}, language = {en} } @incollection{AltherrLeisePfetschetal.2021, author = {Altherr, Lena and Leise, Philipp and Pfetsch, Marc E. and Schmitt, Andreas}, title = {Optimal design of resilient technical systems on the example of water supply systems}, series = {Mastering Uncertainty in Mechanical Engineering}, booktitle = {Mastering Uncertainty in Mechanical Engineering}, publisher = {Springer}, address = {Cham}, isbn = {978-3-030-78356-3}, pages = {429 -- 433}, year = {2021}, language = {en} } @article{AminTemizArtmannArtmannetal.2009, author = {Amin, Rashid and Temiz Artmann, Ayseg{\"u}l and Artmann, Gerhard and Lazarovici, Philip and Lelkes, Peter I.}, title = {Permeability of an In Vitro Model of Blood Brain Barrier (BBB)}, series = {13th International Conference on Biomedical Engineering / Lim, Chwee Teck [Ed.]}, journal = {13th International Conference on Biomedical Engineering / Lim, Chwee Teck [Ed.]}, isbn = {978-3-540-92841-6}, pages = {81 -- 84}, year = {2009}, language = {en} } @inproceedings{AmirBauckhageChircuetal.2022, author = {Amir, Malik and Bauckhage, Christian and Chircu, Alina and Czarnecki, Christian and Knopf, Christian and Piatkowski, Nico and Sultanow, Eldar}, title = {What can we expect from quantum (digital) twins?}, publisher = {AIS Electronic Library (AISeL)}, pages = {1 -- 14}, year = {2022}, abstract = {Digital twins enable the modeling and simulation of real-world entities (objects, processes or systems), resulting in improvements in the associated value chains. The emerging field of quantum computing holds tremendous promise for evolving this virtualization towards Quantum (Digital) Twins (QDT) and ultimately Quantum Twins (QT). The quantum (digital) twin concept is not a contradiction in terms - but instead describes a hybrid approach that can be implemented using the technologies available today by combining classical computing and digital twin concepts with quantum processing. This paper presents the status quo of research and practice on quantum (digital) twins. It also discuses their potential to create competitive advantage through real-time simulation of highly complex, interconnected entities that helps companies better address changes in their environment and differentiate their products and services.}, language = {en} } @article{AndingTabazaStaatetal.2013, author = {Anding, Ralf and Tabaza, Ruth and Staat, Manfred and Trenz, Eva and Lohmann, Philipp and Klinge, Uwe and Kirschner-Hermanns, Ruth}, title = {Introducing a method of in vitro testing of different anchoring systems used for female incontinence and prolapse surgery}, series = {BioMed research international}, volume = {Vol. 2013}, journal = {BioMed research international}, issn = {1110-7251 (E-Journal); 2314-6141 (E-Journal); 1110-7243 (Print); 2314-6133 (Print)}, pages = {Article ID 401417}, year = {2013}, language = {en} } @article{AngermannGuenthnerHanssenetal.2022, author = {Angermann, Susanne and G{\"u}nthner, Roman and Hanssen, Henner and Lorenz, Georg and Braunisch, Matthias C. and Steubl, Dominik and Matschkal, Julia and Kemmner, Stephan and Hausinger, Renate and Block, Zenonas and Haller, Bernhard and Heemann, Uwe and Kotliar, Konstantin and Grimmer, Timo and Schmaderer, Christoph}, title = {Cognitive impairment and microvascular function in end-stage renal disease}, series = {International Journal of Methods in Psychiatric Research (MPR)}, volume = {31}, journal = {International Journal of Methods in Psychiatric Research (MPR)}, number = {2}, publisher = {Wiley}, issn = {1049-8931 (Print)}, doi = {10.1002/mpr.1909}, pages = {1 -- 10}, year = {2022}, abstract = {Objective Hemodialysis patients show an approximately threefold higher prevalence of cognitive impairment compared to the age-matched general population. Impaired microcirculatory function is one of the assumed causes. Dynamic retinal vessel analysis is a quantitative method for measuring neurovascular coupling and microvascular endothelial function. We hypothesize that cognitive impairment is associated with altered microcirculation of retinal vessels. Methods 152 chronic hemodialysis patients underwent cognitive testing using the Montreal Cognitive Assessment. Retinal microcirculation was assessed by Dynamic Retinal Vessel Analysis, which carries out an examination recording retinal vessels' reaction to a flicker light stimulus under standardized conditions. Results In unadjusted as well as in adjusted linear regression analyses a significant association between the visuospatial executive function domain score of the Montreal Cognitive Assessment and the maximum arteriolar dilation as response of retinal arterioles to the flicker light stimulation was obtained. Conclusion This is the first study determining retinal microvascular function as surrogate for cerebral microvascular function and cognition in hemodialysis patients. The relationship between impairment in executive function and reduced arteriolar reaction to flicker light stimulation supports the involvement of cerebral small vessel disease as contributing factor for the development of cognitive impairment in this patient population and might be a target for noninvasive disease monitoring and therapeutic intervention.}, language = {en} } @inproceedings{AnicPenavaGuljasetal.2018, author = {Anic, Filip and Penava, Davorin and Guljas, Ivica and Sarhosis, Vasilis and Abrahamczyk, Lars and Butenweg, Christoph}, title = {The Effect of Openings on Out-of-Plane Capacity of Masonry Infilled Reinforced Concrete Frames}, series = {16th European Conference on Earthquake Engineering, Thessaloniki, 18-21 June, 2018}, booktitle = {16th European Conference on Earthquake Engineering, Thessaloniki, 18-21 June, 2018}, pages = {1 -- 11}, year = {2018}, language = {en} } @inproceedings{AnikFrohberg1989, author = {Anik, Sabri and Frohberg, Martin G.}, title = {Thermodynamic behaviour of oxygen in molten metallic alloys}, series = {Thermochemistry of alloys : recent developments of experimental methods ; [proceedings of the NATO Advanced Study Institute on Thermochemistry of Alloys, Recent Developments of Experimental Methods, Kiel, F.R.G., August 17 - 27, 1987]. - (NATO ASI series : Series C ; 286)}, booktitle = {Thermochemistry of alloys : recent developments of experimental methods ; [proceedings of the NATO Advanced Study Institute on Thermochemistry of Alloys, Recent Developments of Experimental Methods, Kiel, F.R.G., August 17 - 27, 1987]. - (NATO ASI series : Series C ; 286)}, editor = {Brodowsky, Horst}, publisher = {Springer}, address = {Dordrecht [u.a.]}, isbn = {0-7923-0434-9}, pages = {419 -- 428}, year = {1989}, language = {en} } @article{AnikFrohberg1984, author = {Anik, Sabri and Frohberg, Martin G.}, title = {Thermodynamics and solubility of oxygen in liquid copper-lead alloys at 1200°C from E.M.F. measurements}, series = {Berichte der Bunsengesellschaft f{\"u}r physikalische Chemie}, volume = {88}, journal = {Berichte der Bunsengesellschaft f{\"u}r physikalische Chemie}, number = {8}, issn = {0940-483X}, pages = {707 -- 710}, year = {1984}, language = {en} } @article{AnikFrohberg1987, author = {Anik, Sabri and Frohberg, Martin G.}, title = {Thermodynamics and solubility of oxygen in liquid bismuth-lead and bismuth-antimony alloys}, series = {Berichte der Bunsengesellschaft f{\"u}r physikalische Chemie}, volume = {91}, journal = {Berichte der Bunsengesellschaft f{\"u}r physikalische Chemie}, number = {7}, issn = {0940-483X}, pages = {790 -- 794}, year = {1987}, language = {en} } @article{AnikFrohberg1984, author = {Anik, Sabri and Frohberg, Martin G.}, title = {Investigations of the thermodynamics of oxygen and the determination of the miscibility gap in the system copper-oxygen-lead at 12000C}, series = {Zeitschrift f{\"u}r Metallkunde}, volume = {75}, journal = {Zeitschrift f{\"u}r Metallkunde}, number = {8}, issn = {0044-3093}, pages = {586 -- 589}, year = {1984}, language = {en} } @article{AnikFrohberg1983, author = {Anik, Sabri and Frohberg, Martin G.}, title = {Investigation of the thermodynamics of oxygen and the determination of phase boundaries in the system copper-oxygen-bismuth at 12000C}, series = {Zeitschrift f{\"u}r Metallkunde}, volume = {74}, journal = {Zeitschrift f{\"u}r Metallkunde}, number = {8}, issn = {0044-3093}, pages = {530 -- 534}, year = {1983}, language = {en} } @article{AnikFrohberg1988, author = {Anik, Sabri and Frohberg, Martin G.}, title = {Thermodynamics of oxygen in the copper-antimony system at 1473K}, series = {Erzmetall : Rohstoffgewinnung, Verarbeitung, Recycling, Umwelttechnik}, volume = {41}, journal = {Erzmetall : Rohstoffgewinnung, Verarbeitung, Recycling, Umwelttechnik}, number = {10}, issn = {0044-2658}, pages = {498 -- 501}, year = {1988}, language = {en} } @article{AnikFrohbergKapoor1983, author = {Anik, Sabri and Frohberg, Martin G. and Kapoor, Madan Lal}, title = {Experiments and theoretical considerations on the solution of oxygen in binary metal alloys}, series = {Berichte der Bunsengesellschaft f{\"u}r physikalische Chemie}, volume = {87}, journal = {Berichte der Bunsengesellschaft f{\"u}r physikalische Chemie}, number = {12}, issn = {0005-9021}, pages = {1201 -- 1204}, year = {1983}, language = {en} } @article{AnikFrohbergKapoor1983, author = {Anik, Sabri and Frohberg, Martin G. and Kapoor, Madan Lal}, title = {Prediction of thermodynamic properties of oxygen in binary metallic solvents}, series = {Zeitschrift f{\"u}r Metallkunde}, volume = {74}, journal = {Zeitschrift f{\"u}r Metallkunde}, number = {6}, issn = {0044-3093}, pages = {372 -- 375}, year = {1983}, language = {en} } @article{AnikKapoorFrohberg1983, author = {Anik, Sabri and Kapoor, Madan Lal and Frohberg, Martin G.}, title = {Thermodynamic behaviour of oxygen in molten substitutional alloy solvents}, series = {Zeitschrift f{\"u}r Metallkunde}, volume = {74}, journal = {Zeitschrift f{\"u}r Metallkunde}, number = {1}, issn = {0044-3093}, pages = {53 -- 58}, year = {1983}, language = {en} } @inproceedings{AnthrakidisHerrmannSchornetal.2015, author = {Anthrakidis, Anette and Herrmann, Ulf and Schorn, Christian and Schwarzer, Klemens and Wedding, Philipp and Weis, Fabian}, title = {Development and Testing of a Novel Method for the Determination of the Efficiency of Concentrating Solar Thermal Collectors}, series = {Conference Proceedings Solar World Congress 2015, Daegu, Korea, 08 - 12 November 2015}, booktitle = {Conference Proceedings Solar World Congress 2015, Daegu, Korea, 08 - 12 November 2015}, pages = {9 Seiten}, year = {2015}, language = {en} } @inproceedings{AnthrakidisRusackSchwarzer2010, author = {Anthrakidis, Anette and Rusack, Markus and Schwarzer, Klemens}, title = {Low effort measurement method of PTC-efficiency}, series = {SolarPACES 2010 : the CSP conference: electricity, fuels and clean water from concentrated solar energy ; 21 to 24 September 2010, Perpignan, France}, booktitle = {SolarPACES 2010 : the CSP conference: electricity, fuels and clean water from concentrated solar energy ; 21 to 24 September 2010, Perpignan, France}, publisher = {Soc. OSC}, address = {Saint Maur}, pages = {48 -- 49}, year = {2010}, language = {en} } @article{ArampatzisKaramanidisAlbracht2007, author = {Arampatzis, Adamantios and Karamanidis, Kiros and Albracht, Kirsten}, title = {Adaptational responses of the human Achilles tendon by modulation of the applied cyclic strain magnitude}, series = {Journal of Experimental Biology}, volume = {210}, journal = {Journal of Experimental Biology}, number = {15}, issn = {0022-0949}, doi = {10.1242/jeb.003814}, pages = {2743 -- 2753}, year = {2007}, language = {en} } @article{ArampatzisKaramanidisMademlietal.2009, author = {Arampatzis, Adamantios and Karamanidis, Kiros and Mademli, Lida and Albracht, Kirsten}, title = {Plasticity of the human tendon to short and long-term mechanical loading}, series = {Exercise and Sport Sciences Reviews}, volume = {37}, journal = {Exercise and Sport Sciences Reviews}, number = {2}, issn = {1538-3008}, doi = {10.1097/JES.0b013e31819c2e1d}, pages = {66 -- 72}, year = {2009}, language = {en} } @article{ArampatzisPeperBierbaumetal.2010, author = {Arampatzis, Adamantios and Peper, Andreas and Bierbaum, Stefanie and Albracht, Kirsten}, title = {Plasticity of human Achilles tendon mechanical and morphological properties in response to cyclic strain}, series = {Journal of Biomechanics}, volume = {43}, journal = {Journal of Biomechanics}, number = {16}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0021-9290}, doi = {10.1016/j.jbiomech.2010.08.014}, pages = {3073 -- 3079}, year = {2010}, abstract = {The purpose of the current study in combination with our previous published data (Arampatzis et al., 2007) was to examine the effects of a controlled modulation of strain magnitude and strain frequency applied to the Achilles tendon on the plasticity of tendon mechanical and morphological properties. Eleven male adults (23.9±2.2 yr) participated in the study. The participants exercised one leg at low magnitude tendon strain (2.97±0.47\%), and the other leg at high tendon strain magnitude (4.72±1.08\%) of similar frequency (0.5 Hz, 1 s loading, 1 s relaxation) and exercise volume (integral of the plantar flexion moment over time) for 14 weeks, 4 days per week, 5 sets per session. The exercise volume was similar to the intervention of our earlier study (0.17 Hz frequency; 3 s loading, 3 s relaxation) allowing a direct comparison of the results. Before and after the intervention ankle joint moment has been measured by a dynamometer, tendon-aponeurosis elongation by ultrasound and cross-sectional area of the Achilles tendon by magnet resonance images (MRI). We found a decrease in strain at a given tendon force, an increase in tendon-aponeurosis stiffness and tendon elastic modulus of the Achilles tendon only in the leg exercised at high strain magnitude. The cross-sectional area (CSA) of the Achilles tendon did not show any statistically significant (P>0.05) differences to the pre-exercise values in both legs. The results indicate a superior improvement in tendon properties (stiffness, elastic modulus and CSA) at the low frequency (0.17 Hz) compared to the high strain frequency (0.5 Hz) protocol. These findings provide evidence that the strain magnitude applied to the Achilles tendon should exceed the value, which occurs during habitual activities to trigger adaptational effects and that higher tendon strain duration per contraction leads to superior tendon adaptational responses.}, language = {en} } @article{AridaAlhaddadSchoening2011, author = {Arida, Hassan A. and Al-haddad, Ameera and Sch{\"o}ning, Michael Josef}, title = {New Solid-State Organic Membrane Based Lead-Selective Micro-Electrode}, series = {International Journal of Electrochemical Science. 6 (2011), H. 9}, journal = {International Journal of Electrochemical Science. 6 (2011), H. 9}, isbn = {1452-3981}, pages = {3858 -- 3867}, year = {2011}, language = {en} } @inproceedings{AridaKloockSchoening2006, author = {Arida, Hassan A. and Kloock, Joachim P. and Sch{\"o}ning, Michael Josef}, title = {Novel organic membrane-based thin-film microsensors for the determination of heavy metal cations}, url = {http://nbn-resolving.de/urn:nbn:de:hbz:a96-opus-1545}, year = {2006}, abstract = {A first step towards the fabrication and electrochemical evaluation of thin-film microsensors based on organic PVC membranes for the determination of Hg(II), Cd(II), Pb(II) and Cu(II) ions in solutions has been realised. The membrane-coating mixture used in the preparation of this new type of microsensors is incorporating PVC as supporting matrix, o-nitrophenyloctylether (o-NPOE) as solvent mediator and a recently synthesized Hg[dimethylglyoxime(phene)]2+ and Bis-(4-hydroxyacetophenone)-ethylenediamine as electroactive materials for Hg(II) and Cd(II), respectively. A set of three commercialised ionophores for Cd(II), Pb(II) and Cu(II) has been also used for comparison. Thin-film microsensors based on these membranes showed a Nernstian response of slope (26-30 mV/dec.) for the respective tested cations. The potentiometric response characteristics (linear range, pH range, detection limit and response time) are comparable with those obtained by conventional membranes as well as coated wire electrodes prepared from the same membrane. The realisation of the new organic membrane-based thin-film microsensors overcomes the problem of an insufficient selectivity of solid-state-based thinfilm sensors.}, subject = {Biosensor}, language = {en} } @article{AridaMohsenSchoening2009, author = {Arida, Hassan and Mohsen, Q. and Sch{\"o}ning, Michael Josef}, title = {Microfabrication, characterization and analytical application of a new thin-film silver microsensor}, series = {Electrochimica Acta. 54 (2009), H. 13}, journal = {Electrochimica Acta. 54 (2009), H. 13}, isbn = {0013-4686}, pages = {3543 -- 3547}, year = {2009}, language = {en} } @article{AridaTurekRolkaetal.2009, author = {Arida, Hassan and Turek, Monika and Rolka, David and Sch{\"o}ning, Michael Josef}, title = {A Novel Thin-Film Copper Array Based on an Organic/Inorganic Sensor Hybrid: Microfabrication, Potentiometric Characterization, and Flow-Injection Analysis Application}, series = {Electroanalysis. 21 (2009), H. 10}, journal = {Electroanalysis. 21 (2009), H. 10}, publisher = {Wiley}, address = {Weinheim}, isbn = {1040-0397}, pages = {1145 -- 1151}, year = {2009}, language = {en} } @inproceedings{AringhoffGeyerHerrmannetal.2002, author = {Aringhoff, R. and Geyer, Michael and Herrmann, Ulf and Kistner, Rainer and Nava, P. and Osuna, R.}, title = {AndaSol : 50MW Solar Plants with 9 Hour Storage for Southern Spain}, series = {Proceedings of the 11th SolarPACES International Symposium on Concentrated Solar Power and Chemical Energy Technologies : September 4 - 6, 2002, Zurich, Switzerland / Paul Scherrer Institut, PSI; ETH, Eidgen{\"o}ssische Technische Hochschule Z{\"u}rich}, booktitle = {Proceedings of the 11th SolarPACES International Symposium on Concentrated Solar Power and Chemical Energy Technologies : September 4 - 6, 2002, Zurich, Switzerland / Paul Scherrer Institut, PSI; ETH, Eidgen{\"o}ssische Technische Hochschule Z{\"u}rich}, editor = {Steinfeld, Aldo}, publisher = {Paul Scherrer Inst.}, address = {Villingen}, isbn = {3-9521409-3-7}, pages = {37 -- 42}, year = {2002}, language = {en} } @inproceedings{ArinkinDigel2009, author = {Arinkin, Vladimir and Digel, Ilya}, title = {Water bridge phenomenon : [abstract]}, year = {2009}, abstract = {One of interesting but not well known water properties is related to appearance of highly ordered structures in response to strong electrical field. In 1893 Sir William Armstrong placed a cotton thread between two wine glasses filled with chemically pure water. When high DC voltage was applied between the glasses, a connection consisting of water formed, producing a "water bridge"}, subject = {Hydrodynamik}, language = {en} } @article{ArinkinDigelPorstetal.2014, author = {Arinkin, Vladimir and Digel, Ilya and Porst, Dariusz and Temiz Artmann, Ayseg{\"u}l and Artmann, Gerhard}, title = {Phenotyping date palm varieties via leaflet cross-sectional imaging and artificial neural network application}, series = {BMC bioinformatics}, volume = {15}, journal = {BMC bioinformatics}, number = {55}, issn = {1471-2105}, doi = {10.1186/1471-2105-15-55}, pages = {1 -- 8}, year = {2014}, abstract = {Background True date palms (Phoenix dactylifera L.) are impressive trees and have served as an indispensable source of food for mankind in tropical and subtropical countries for centuries. The aim of this study is to differentiate date palm tree varieties by analysing leaflet cross sections with technical/optical methods and artificial neural networks (ANN). Results Fluorescence microscopy images of leaflet cross sections have been taken from a set of five date palm tree cultivars (Hewlat al Jouf, Khlas, Nabot Soltan, Shishi, Um Raheem). After features extraction from images, the obtained data have been fed in a multilayer perceptron ANN with backpropagation learning algorithm. Conclusions Overall, an accurate result in prediction and differentiation of date palm tree cultivars was achieved with average prediction in tenfold cross-validation is 89.1\% and reached 100\% in one of the best ANN.}, language = {en} } @inproceedings{ArndtConzenElsenetal.2023, author = {Arndt, Tobias and Conzen, Max and Elsen, Ingo and Ferrein, Alexander and Galla, Oskar and K{\"o}se, Hakan and Schiffer, Stefan and Tschesche, Matteo}, title = {Anomaly detection in the metal-textile industry for the reduction of the cognitive load of quality control workers}, series = {PETRA '23: Proceedings of the 16th International Conference on PErvasive Technologies Related to Assistive Environments}, booktitle = {PETRA '23: Proceedings of the 16th International Conference on PErvasive Technologies Related to Assistive Environments}, publisher = {ACM}, isbn = {9798400700699}, doi = {10.1145/3594806.3596558}, pages = {535 -- 542}, year = {2023}, abstract = {This paper presents an approach for reducing the cognitive load for humans working in quality control (QC) for production processes that adhere to the 6σ -methodology. While 100\% QC requires every part to be inspected, this task can be reduced when a human-in-the-loop QC process gets supported by an anomaly detection system that only presents those parts for manual inspection that have a significant likelihood of being defective. This approach shows good results when applied to image-based QC for metal textile products.}, language = {en} } @article{ArpshofenPoolSommeretal.1983, author = {Arpshofen, Ingo and Pool, M. J. and Sommer, Ferdinand and Gerling, Ulrich and Predel, Bruno and Schultheiss, Emil}, title = {Determination of the integral mixing enthalpies in the Cu-Pd-Si liquid ternary alloy system at 1600 K}, series = {Zeitschrift f{\"u}r Metallkunde : international journal of materials research and advanced techniques. Bd. 74, H. 1}, journal = {Zeitschrift f{\"u}r Metallkunde : international journal of materials research and advanced techniques. Bd. 74, H. 1}, issn = {0044-3093 ; 0179-4841}, pages = {25 -- 32}, year = {1983}, language = {en} } @article{ArreolaKeusgenSchoening2017, author = {Arreola, Julio and Keusgen, Michael and Sch{\"o}ning, Michael Josef}, title = {Effect of O2 plasma on properties of electrolyte-insulator-semiconductor structures}, series = {physica status solidi a : applications and materials sciences}, volume = {214}, journal = {physica status solidi a : applications and materials sciences}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {1862-6319}, doi = {10.1002/pssa.201700025}, pages = {Artikel 1700025}, year = {2017}, abstract = {Prior to immobilization of biomolecules or cells onto biosensor surfaces, the surface must be physically or chemically activated for further functionalization. Organosilanes are a versatile option as they facilitate the immobilization through their terminal groups and also display self-assembly. Incorporating hydroxyl groups is one of the important methods for primary immobilization. This can be done, for example, with oxygen plasma treatment. However, this treatment can affect the performance of the biosensors and this effect is not quite well understood for surface functionalization. In this work, the effect of O2 plasma treatment on EIS sensors was investigated by means of electrochemical characterizations: capacitance-voltage (C-V) and constant capacitance (ConCap) measurements. After O2 plasma treatment, the potential of the EIS sensor dramatically shifts to a more negative value. This was successfully reset by using an annealing process.}, language = {en} } @article{ArreolaKeusgenSchoening2019, author = {Arreola, Julio and Keusgen, Michael and Sch{\"o}ning, Michael Josef}, title = {Toward an immobilization method for spore-based biosensors in oxidative environment}, series = {Electrochimica Acta}, volume = {302}, journal = {Electrochimica Acta}, publisher = {Elsevier}, address = {Amsterdam}, doi = {10.1016/j.electacta.2019.01.148}, pages = {394 -- 401}, year = {2019}, language = {en} } @article{ArreolaKeusgenWagneretal.2019, author = {Arreola, Julio and Keusgen, Michael and Wagner, Torsten and Sch{\"o}ning, Michael Josef}, title = {Combined calorimetric gas- and spore-based biosensor array for online monitoring and sterility assurance of gaseous hydrogen peroxide in aseptic filling machines}, series = {Biosensors and Bioelectronics}, volume = {143}, journal = {Biosensors and Bioelectronics}, number = {111628}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0956-5663}, doi = {10.1016/j.bios.2019.111628}, year = {2019}, language = {en} } @article{ArreolaMaetzkowDuranetal.2016, author = {Arreola, Julio and M{\"a}tzkow, Malte and Dur{\´a}n, Marlena Palomar and Greeff, Anton and Keusgen, Michael and Sch{\"o}ning, Michael Josef}, title = {Optimization of the immobilization of bacterial spores on glass substrates with organosilanes}, series = {Physica status solidi (A) : Applications and materials science}, volume = {213}, journal = {Physica status solidi (A) : Applications and materials science}, number = {6}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {1862-6319}, doi = {10.1002/pssa.201532914}, pages = {1463 -- 1470}, year = {2016}, abstract = {Spores can be immobilized on biosensors to function as sensitive recognition elements. However, the immobilization can affect the sensitivity and reproducibility of the sensor signal. In this work, three different immobilization strategies with organosilanes were optimized and characterized to immobilize Bacillus atrophaeus spores on glass substrates. Five different silanization parameters were investigated: nature of the solvent, concentration of the silane, silanization time, curing process, and silanization temperature. The resulting silane layers were resistant to a buffer solution (e.g., Ringer solution) with a polysorbate (e.g., Tween®80) and sonication.}, language = {en} } @article{ArreolaOberlaenderMaetzkowetal.2017, author = {Arreola, Julio and Oberl{\"a}nder, Jan and M{\"a}tzkow, M. and Keusgen, Michael and Sch{\"o}ning, Michael Josef}, title = {Surface functionalization for spore-based biosensors with organosilanes}, series = {Electrochimica Acta}, volume = {241}, journal = {Electrochimica Acta}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0013-4686}, doi = {10.1016/j.electacta.2017.04.157}, pages = {237 -- 243}, year = {2017}, abstract = {In the present work, surface functionalization of different sensor materials was studied. Organosilanes are well known to serve as coupling agent for biomolecules or cells on inorganic materials. 3-aminopropyltriethoxysilane (APTES) was used to attach microbiological spores time to an interdigitated sensor surface. The functionality and physical properties of APTES were studied on isolated sensor materials, namely silicon dioxide (SiO2) and platinum (Pt) as well as the combined material on sensor level. A predominant immobilization of spores could be demonstrated on SiO2 surfaces. Additionally, the impedance signal of APTES-functionalized biosensor chips has been investigated.}, language = {en} } @article{Artmann1986, author = {Artmann, Gerhard}, title = {A microscopic photometric method for measuring erythrocyte deformability. Artmann, Gerhard Michael}, series = {Clinical Hemorheology. 6 (1986)}, journal = {Clinical Hemorheology. 6 (1986)}, isbn = {0271-5198}, pages = {617 -- 627}, year = {1986}, language = {en} } @article{Artmann1996, author = {Artmann, Gerhard}, title = {2nd International Conference on Medical Biorheology (ICMB). Shanghai, China, September 13-15, 1995. Shi, Young de, Artmann, Gerhard Michael, Meiselman, Herbert J.}, series = {Biorheology. 33 (1996), H. 6}, journal = {Biorheology. 33 (1996), H. 6}, isbn = {0006-355x}, pages = {505 -- 507}, year = {1996}, language = {en} } @article{Artmann1995, author = {Artmann, Gerhard}, title = {Microscopic photometric quantification of stiffness and relaxation time of red blood cells in a flow chamber. Artmann, Gerhard Michael}, series = {Biorheology. 32 (1995), H. 5}, journal = {Biorheology. 32 (1995), H. 5}, isbn = {0006-355x}, pages = {553 -- 570}, year = {1995}, language = {en} } @book{Artmann2008, author = {Artmann, Gerhard}, title = {Bioengineering in Cell and Tissue Research / Artmann, Gerhard M. ; Chien, Shu (Eds.)}, publisher = {Springer}, address = {Berlin}, isbn = {978-3-540-75408-4}, year = {2008}, language = {en} } @article{Artmann2000, author = {Artmann, Gerhard}, title = {Cellular engineering - a challenge for engineers? / Artmann, G. M.}, series = {Biomedizinische Technik = Biomedical Engineering. 45 (2000), H. s1}, journal = {Biomedizinische Technik = Biomedical Engineering. 45 (2000), H. s1}, isbn = {1862-278X}, pages = {449}, year = {2000}, language = {en} } @book{Artmann2011, author = {Artmann, Gerhard}, title = {Stem cell engineering : principles and applications / Gerhard M. Artmann ... eds.}, publisher = {Springer}, address = {Berlin [u.a.]}, isbn = {978-3-642-11864-7}, pages = {XLI, 541 S. : Ill., graph. Darst.}, year = {2011}, language = {en} } @article{ArtmannBurnsCanavesetal.2004, author = {Artmann, Gerhard and Burns, Laura and Canaves, Jaume M. and Temiz Artmann, Ayseg{\"u}l}, title = {Circular dichroism spectra of human hemoglobin reveal a reversible structural transition at body temperature}, series = {European Biophysics Journal. 33 (2004), H. 6}, journal = {European Biophysics Journal. 33 (2004), H. 6}, isbn = {1432-1017}, pages = {490 -- 496}, year = {2004}, language = {en} }