@inproceedings{RosinButenwegBoesenetal.2018,
  author    = {Rosin, Julia and Butenweg, Christoph and Boesen, Niklas and Gellert, Christoph},
  title     = {Evaluation of the Seismic Behavior of a Modern URM Building During the 2012 Northern Italy Earthquakes},
  series = {16th European Conference on Earthquake Engineering, Thessaloniki, 18-21 June, 2018},
  booktitle = {16th European Conference on Earthquake Engineering, Thessaloniki, 18-21 June, 2018},
  pages     = {1 -- 12},
  year      = {2018},
  language  = {en}
}
@article{RodriguesMoraisNordietal.2018,
  author    = {Rodrigues, Raul T. and Morais, Paulo V. and Nordi, Cristina S. F. and Sch{\"o}ning, Michael Josef and Siqueira Jr., Jos{\´e} R. and Caseli, Luciano},
  title     = {Carbon Nanotubes and Algal Polysaccharides To Enhance the Enzymatic Properties of Urease in Lipid Langmuir-Blodgett Films},
  series = {Langmuir},
  volume    = {34},
  journal   = {Langmuir},
  number    = {9},
  publisher = {ACS Publications},
  address   = {Washington, DC},
  issn      = {1520-5827},
  doi       = {10.1021/acs.langmuir.7b04317},
  pages     = {3082 -- 3093},
  year      = {2018},
  abstract  = {Algal polysaccharides (extracellular polysaccharides) and carbon nanotubes (CNTs) were adsorbed on dioctadecyldimethylammonium bromide Langmuir monolayers to serve as a matrix for the incorporation of urease. The physicochemical properties of the supramolecular system as a monolayer at the air-water interface were investigated by surface pressure-area isotherms, surface potential-area isotherms, interfacial shear rheology, vibrational spectroscopy, and Brewster angle microscopy. The floating monolayers were transferred to hydrophilic solid supports, quartz, mica, or capacitive electrolyte-insulator-semiconductor (EIS) devices, through the Langmuir-Blodgett (LB) technique, forming mixed films, which were investigated by quartz crystal microbalance, fluorescence spectroscopy, and field emission gun scanning electron microscopy. The enzyme activity was studied with UV-vis spectroscopy, and the feasibility of the thin film as a urea sensor was essayed in an EIS sensor device. The presence of CNT in the enzyme-lipid LB film not only tuned the catalytic activity of urease but also helped to conserve its enzyme activity. Viability as a urease sensor was demonstrated with capacitance-voltage and constant capacitance measurements, exhibiting regular and distinctive output signals over all concentrations used in this work. These results are related to the synergism between the compounds on the active layer, leading to a surface morphology that allowed fast analyte diffusion owing to an adequate molecular accommodation, which also preserved the urease activity. This work demonstrates the feasibility of employing LB films composed of lipids, CNT, algal polysaccharides, and enzymes as EIS devices for biosensing applications.},
  language  = {en}
}
@article{RittwegerAlbrachtFluecketal.2018,
  author    = {Rittweger, J{\"o}rn and Albracht, Kirsten and Fl{\"u}ck, Martin and Ruoss, Severin and Brocca, Lorenza and Longa, Emanuela and Moriggi, Manuela and Seynnes, Olivier and Di Giulio, Irene and Tenori, Leonardo and Vignoli, Alessia and Capri, Miriam and Gelfi, Cecilia and Luchinat, Claudio and Franceschi, Claudio and Bottinelli, Roberto and Cerretelli, Paolo and Narici, Marco},
  title     = {Sarcolab pilot study into skeletal muscle's adaptation to longterm spaceflight},
  series = {npj Microgravity},
  volume    = {4},
  journal   = {npj Microgravity},
  number    = {1},
  publisher = {Nature Portfolio},
  issn      = {2373-8065},
  doi       = {10.1038/s41526-018-0052-1},
  pages     = {1 -- 9},
  year      = {2018},
  language  = {en}
}
@article{RiekeStollenwerkDahmenetal.2018,
  author    = {Rieke, Christian and Stollenwerk, Dominik and Dahmen, Markus and Pieper, Martin},
  title     = {Modeling and optimization of a biogas plant for a demand-driven energy supply},
  series = {Energy},
  volume    = {145},
  journal   = {Energy},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0360-5442},
  doi       = {10.1016/j.energy.2017.12.073},
  pages     = {657 -- 664},
  year      = {2018},
  abstract  = {Due to the Renewable Energy Act, in Germany it is planned to increase the amount of renewable energy carriers up to 60\%. One of the main problems is the fluctuating supply of wind and solar energy. Here biogas plants provide a solution, because a demand-driven supply is possible. Before running such a plant, it is necessary to simulate and optimize the process. This paper provides a new model of a biogas plant, which is as accurate as the standard ADM1 model. The advantage compared to ADM1 is that it is based on only four parameters compared to 28. Applying this model, an optimization was installed, which allows a demand-driven supply by biogas plants. Finally the results are confirmed by several experiments and measurements with a real test plant.},
  language  = {en}
}
@inproceedings{RichterBraunsteinStaeudleetal.2018,
  author    = {Richter, Charlotte and Braunstein, Bjoern and St{\"a}udle, Benjamin and Attias, Julia and Suess, Alexander and Weber, T. and Rittweger, Joern and Green, David A. and Albracht, Kirsten},
  title     = {In vivo fascicle length of the gastrocnemius muscle during walking in simulated martian gravity using two different body weight support devices},
  series = {23rd Annual Congress of the European College of Sport Science, Dublin, Irland},
  booktitle = {23rd Annual Congress of the European College of Sport Science, Dublin, Irland},
  year      = {2018},
  language  = {en}
}
@inproceedings{RendonDieckmannWeidleetal.2018,
  author    = {Rendon, Carlos and Dieckmann, Simon and Weidle, Mathias and Dersch, J{\"u}rgen and Teixeira Boura, Cristiano Jos{\´e} and Polklas, Thomas and Kuschel, Marcus and Herrmann, Ulf},
  title     = {Retrofitting of existing parabolic trough collector power plants with molten salt tower systems},
  series = {AIP Conference Proceedings},
  volume    = {2033},
  booktitle = {AIP Conference Proceedings},
  number    = {1},
  doi       = {10.1063/1.5067030},
  pages     = {030014-1 -- 030014-8},
  year      = {2018},
  language  = {en}
}
@inproceedings{RauschFriesenAltherretal.2018,
  author    = {Rausch, Lea and Friesen, John and Altherr, Lena and Pelz, Peter F.},
  title     = {Using mixed-integer programming for the optimal design of water supply networks for slums},
  series = {Operations Research Proceedings 2017},
  booktitle = {Operations Research Proceedings 2017},
  editor    = {Kliewer, Natalia and Ehmke, Jan Fabian and Bornd{\"o}rfer, Ralf},
  publisher = {Springer},
  address   = {Cham},
  isbn      = {978-3-319-89919-0 (Print)},
  doi       = {10.1007/978-3-319-89920-6_68},
  pages     = {509 -- 516},
  year      = {2018},
  abstract  = {The UN sets the goal to ensure access to water and sanitation for all people by 2030. To address this goal, we present a multidisciplinary approach for designing water supply networks for slums in large cities by applying mathematical optimization. The problem is modeled as a mixed-integer linear problem (MILP) aiming to find a network describing the optimal supply infrastructure. To illustrate the approach, we apply it on a small slum cluster in Dhaka, Bangladesh.},
  language  = {en}
}
@article{RauschFriesenAltherretal.2018,
  author    = {Rausch, Lea and Friesen, John and Altherr, Lena and Meck, Marvin and Pelz, Peter F.},
  title     = {A holistic concept to design optimal water supply infrastructures for informal settlements using remote sensing data},
  series = {Remote Sensing},
  volume    = {10},
  journal   = {Remote Sensing},
  number    = {2},
  publisher = {MDPI},
  address   = {Basel},
  isbn      = {2072-4292},
  doi       = {10.3390/rs10020216},
  pages     = {1 -- 23},
  year      = {2018},
  abstract  = {Ensuring access to water and sanitation for all is Goal No. 6 of the 17 UN Sustainability Development Goals to transform our world. As one step towards this goal, we present an approach that leverages remote sensing data to plan optimal water supply networks for informal urban settlements. The concept focuses on slums within large urban areas, which are often characterized by a lack of an appropriate water supply. We apply methods of mathematical optimization aiming to find a network describing the optimal supply infrastructure. Hereby, we choose between different decentral and central approaches combining supply by motorized vehicles with supply by pipe systems. For the purposes of illustration, we apply the approach to two small slum clusters in Dhaka and Dar es Salaam. We show our optimization results, which represent the lowest cost water supply systems possible. Additionally, we compare the optimal solutions of the two clusters (also for varying input parameters, such as population densities and slum size development over time) and describe how the result of the optimization depends on the entered remote sensing data.},
  language  = {en}
}
@article{RauppSchmittWalzetal.2018,
  author    = {Raupp, Sebastian M. and Schmitt, Marcel and Walz, Anna-Lena and Diehm, Ralf and Hummel, Helga and Scharfer, Philip and Schabel, Wilhelm},
  title     = {Slot die stripe coating of low viscous fluids},
  series = {Journal of Coatings Technology and Research},
  volume    = {15},
  journal   = {Journal of Coatings Technology and Research},
  number    = {5},
  publisher = {Springer},
  issn      = {1935-3804},
  doi       = {10.1007/s11998-017-0039-y},
  pages     = {899 -- 911},
  year      = {2018},
  abstract  = {Slot die coating is applied to deposit thin and homogenous films in roll-to-roll and sheet-to-sheet applications. The critical step in operation is to choose suitable process parameters within the process window. In this work, we investigate an upper limit for stripe coatings. This maximum film thickness is characterized by stripe merging which needs to be avoided in a stable process. It is shown that the upper limit reduces the process window for stripe coatings to a major extent. As a result, stripe coatings at large coating gaps and low viscosities are only possible for relatively thick films. Explaining the upper limit, a theory of balancing the side pressure in the gap region in the cross-web direction has been developed.},
  language  = {en}
}
@article{RabehiGarlanAchtsnichtetal.2018,
  author    = {Rabehi, Amine and Garlan, Benjamin and Achtsnicht, Stefan and Krause, Hans-Joachim and Offenh{\"a}usser, Andreas and Ngo, Kieu and Neveu, Sophie and Graff-Dubois, Stephanie and Kokabi, Hamid},
  title     = {Magnetic detection structure for Lab-on-Chip applications based on the frequency mixing technique},
  series = {Sensors},
  volume    = {18},
  journal   = {Sensors},
  number    = {6},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {1424-8220},
  doi       = {10.3390/s18061747},
  pages     = {14 Seiten},
  year      = {2018},
  abstract  = {A magnetic frequency mixing technique with a set of miniaturized planar coils was investigated for use with a completely integrated Lab-on-Chip (LoC) pathogen sensing system. The system allows the detection and quantification of superparamagnetic beads. Additionally, in terms of magnetic nanoparticle characterization ability, the system can be used for immunoassays using the beads as markers. Analytical calculations and simulations for both excitation and pick-up coils are presented; the goal was to investigate the miniaturization of simple and cost-effective planar spiral coils. Following these calculations, a Printed Circuit Board (PCB) prototype was designed, manufactured, and tested for limit of detection, linear response, and validation of theoretical concepts. Using the magnetic frequency mixing technique, a limit of detection of 15 µg/mL of 20 nm core-sized nanoparticles was achieved without any shielding.},
  language  = {en}
}
@article{QuittmannMeskemperAbeletal.2018,
  author    = {Quittmann, Oliver J. and Meskemper, Joshua and Abel, Thomas and Albracht, Kirsten and Foitschik, Tina and Rojas-Vega, Sandra and Str{\"u}der, Heiko K.},
  title     = {Kinematics and kinetics of handcycling propulsion at increasing workloads in able-bodied subjects},
  series = {Sports Engineereing},
  volume    = {21},
  journal   = {Sports Engineereing},
  number    = {21},
  publisher = {Springer Nature},
  address   = {Cham},
  issn      = {1460-2687},
  doi       = {10.1007/s12283-018-0269-y},
  pages     = {283 -- 294},
  year      = {2018},
  abstract  = {In Paralympic sports, biomechanical optimisation of movements and equipment seems to be promising for improving performance. In handcycling, information about the biomechanics of this sport is mainly provided by case studies. The aim of the current study was (1) to examine changes in handcycling propulsion kinematics and kinetics due to increasing workloads and (2) identify parameters that are associated with peak aerobic performance. Twelve non-disabled male competitive triathletes without handcycling experience voluntarily participated in the study. They performed an initial familiarisation protocol and incremental step test until exhaustion in a recumbent racing handcycle that was attached to an ergometer. During the incremental test, tangential crank kinetics, 3D joint kinematics, blood lactate and ratings of perceived exertion (local and global) were identified. As a performance criterion, the maximal power output during the step test (Pmax) was calculated and correlated with biomechanical parameters. For higher workloads, an increase in crank torque was observed that was even more pronounced in the pull phase than in the push phase. Furthermore, participants showed an increase in shoulder internal rotation and abduction and a decrease in elbow flexion and retroversion. These changes were negatively correlated with performance. At high workloads, it seems that power output is more limited by the transition from pull to push phase than at low workloads. It is suggested that successful athletes demonstrate small alterations of their kinematic profile due to increasing workloads. Future studies should replicate and expand the test spectrum (sprint and continuous loads) as well as use methods like surface electromyography (sEMG) with elite handcyclists.},
  language  = {de}
}
@article{PuppeGiulianoFrantzetal.2018,
  author    = {Puppe, Michael and Giuliano, Stefano and Frantz, Cathy and Uhlig, Ralf and Schumacher, Ralph and Ibraheem, Wagdi and Schmalz, Stefan and Waldmann, Barbara and Guder, Christoph and Peter, Dennis and Schwager, Christian and Teixeira Boura, Cristiano Jos{\´e} and Alexopoulos, Spiros and Spiegel, Michael and Wortmann, J{\"u}rgen and Hinrichs, Matthias and Engelhard, Manfred and Aust, Michael},
  title     = {Techno-economic optimization of molten salt solar tower plants},
  series = {AIP Conference Proceedings art.no. 040033},
  volume    = {2033},
  journal   = {AIP Conference Proceedings art.no. 040033},
  number    = {Issue 1},
  publisher = {AIP Publishing},
  address   = {Melville, NY},
  doi       = {10.1063/1.5067069},
  year      = {2018},
  abstract  = {In this paper the results of a techno-economic analysis of improved and optimized molten salt solar tower plants (MSSTP plants) are presented. The potential improvements that were analyzed include different receiver designs, different designs of the HTF-system and plant control, increased molten salt temperatures (up to 640°C) and multi-tower systems. Detailed technological and economic models of the solar field, solar receiver and high temperature fluid system (HTF-system) were developed and used to find potential improvements compared to a reference plant based on Solar Two technology and up-to-date cost estimations. The annual yield model calculates the annual outputs and the LCOE of all variants. An improved external tubular receiver and improved HTF-system achieves a significant decrease of LCOE compared to the reference. This is caused by lower receiver cost as well as improvements of the HTF-system and plant operation strategy, significantly reducing the plant own consumption. A novel star receiver shows potential for further cost decrease. The cavity receiver concepts result in higher LCOE due to their high investment cost, despite achieving higher efficiencies. Increased molten salt temperatures seem possible with an adapted, closed loop HTF-system and achieve comparable results to the original improved system (with 565°C) under the given boundary conditions. In this analysis all multi tower systems show lower economic viability compared to single tower systems, caused by high additional cost for piping connections and higher cost of the receivers. REFERENCES},
  language  = {en}
}
@article{PoghossianJablonskiKochetal.2018,
  author    = {Poghossian, Arshak and Jablonski, Melanie and Koch, Claudia and Bronder, Thomas and Rolka, David and Wege, Christina and Sch{\"o}ning, Michael Josef},
  title     = {Field-effect biosensor using virus particles as scaffolds for enzyme immobilization},
  series = {Biosensors and Bioelectronics},
  volume    = {110},
  journal   = {Biosensors and Bioelectronics},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0956-5663},
  doi       = {10.1016/j.bios.2018.03.036},
  pages     = {168 -- 174},
  year      = {2018},
  abstract  = {A field-effect biosensor employing tobacco mosaic virus (TMV) particles as scaffolds for enzyme immobilization is presented. Nanotubular TMV scaffolds allow a dense immobilization of precisely positioned enzymes with retained activity. To demonstrate feasibility of this new strategy, a penicillin sensor has been developed by coupling a penicillinase with virus particles as a model system. The developed field-effect penicillin biosensor consists of an Al-p-Si-SiO₂-Ta₂O₅-TMV structure and has been electrochemically characterized in buffer solutions containing different concentrations of penicillin G. In addition, the morphology of the biosensor surface with virus particles was characterized by scanning electron microscopy and atomic force microscopy methods. The sensors possessed a high penicillin sensitivity of ~ 92 mV/dec in a nearly-linear range from 0.1 mM to 10 mM, and a low detection limit of about 50 µM. The long-term stability of the penicillin biosensor was periodically tested over a time period of about one year without any significant loss of sensitivity. The biosensor has also been successfully applied for penicillin detection in bovine milk samples.},
  language  = {en}
}
@article{PilasYaziciSelmeretal.2018,
  author    = {Pilas, Johanna and Yazici, Y. and Selmer, Thorsten and Keusgen, M. and Sch{\"o}ning, Michael Josef},
  title     = {Application of a portable multi-analyte biosensor for organic acid determination in silage},
  series = {Sensors},
  volume    = {18},
  journal   = {Sensors},
  number    = {5},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {1424-8220},
  doi       = {10.3390/s18051470},
  pages     = {12 Seiten},
  year      = {2018},
  abstract  = {Multi-analyte biosensors may offer the opportunity to perform cost-effective and rapid analysis with reduced sample volume, as compared to electrochemical biosensing of each analyte individually. This work describes the development of an enzyme-based biosensor system for multi-parametric determination of four different organic acids. The biosensor array comprises five working electrodes for simultaneous sensing of ethanol, formate, d-lactate, and l-lactate, and an integrated counter electrode. Storage stability of the biosensor was evaluated under different conditions (stored at +4 °C in buffer solution and dry at -21 °C, +4 °C, and room temperature) over a period of 140 days. After repeated and regular application, the individual sensing electrodes exhibited the best stability when stored at -21 °C. Furthermore, measurements in silage samples (maize and sugarcane silage) were conducted with the portable biosensor system. Comparison with a conventional photometric technique demonstrated successful employment for rapid monitoring of complex media.},
  language  = {en}
}
@inproceedings{Pieper2018,
  author    = {Pieper, Martin},
  title     = {Digitale Hochschullehre in mathematischen und mathematikdidaktischen Veranstaltungen},
  series = {Beitr{\"a}ge zum Mathematikunterricht 2018 : Vortr{\"a}ge zur Mathematikdidaktik und zur Schnittstelle Mathematik/Mathematikdidaktik auf der gemeinsamen Jahrestagung GDM und DMV 2018 (52. Jahrestagung der Gesellschaft f{\"u}r Didaktik der Mathematik). Bd. 1},
  booktitle = {Beitr{\"a}ge zum Mathematikunterricht 2018 : Vortr{\"a}ge zur Mathematikdidaktik und zur Schnittstelle Mathematik/Mathematikdidaktik auf der gemeinsamen Jahrestagung GDM und DMV 2018 (52. Jahrestagung der Gesellschaft f{\"u}r Didaktik der Mathematik). Bd. 1},
  publisher = {WTM-Verlag},
  address   = {M{\"u}nster},
  isbn      = {978-3-95987-089-4},
  pages     = {105 -- 106},
  year      = {2018},
  language  = {de}
}
@inproceedings{Pieper2018,
  author    = {Pieper, Martin},
  title     = {Lernzielorientierte Kurse und Stack Aufgaben in der Mathematikausbildung},
  series = {Beitr{\"a}ge zum Mathematikunterricht 2018 : Vortr{\"a}ge zur Mathematikdidaktik und zur Schnittstelle Mathematik/Mathematikdidaktik auf der gemeinsamen Jahrestagung GDM und DMV 2018 (52. Jahrestagung der Gesellschaft f{\"u}r Didaktik der Mathematik). Bd. 3},
  booktitle = {Beitr{\"a}ge zum Mathematikunterricht 2018 : Vortr{\"a}ge zur Mathematikdidaktik und zur Schnittstelle Mathematik/Mathematikdidaktik auf der gemeinsamen Jahrestagung GDM und DMV 2018 (52. Jahrestagung der Gesellschaft f{\"u}r Didaktik der Mathematik). Bd. 3},
  publisher = {WTM-Verlag},
  address   = {M{\"u}nster},
  isbn      = {978-3-95987-089-4},
  pages     = {1399 -- 1402},
  year      = {2018},
  language  = {de}
}
@incollection{PielenRoethFlatten2018,
  author    = {Pielen, Michael and R{\"o}th, Thilo and Flatten, T.},
  title     = {Erfolgsfaktoren k{\"u}nftiger Gesch{\"a}ftsmodelle von urbanen, geteilten Mobilit{\"a}tsdienstleistungen},
  series = {Mobilit{\"a}t und digitale Transformation. (9. Wissenschaftsforum Mobilit{\"a}t. Tagungsband)},
  booktitle = {Mobilit{\"a}t und digitale Transformation. (9. Wissenschaftsforum Mobilit{\"a}t. Tagungsband)},
  editor    = {Proff, H.},
  publisher = {Springer Gabler},
  address   = {Wiesbaden},
  isbn      = {978-3-658-20779-3},
  doi       = {10.1007/978-3-658-20779-3_2},
  pages     = {435 -- 448},
  year      = {2018},
  abstract  = {Digitalisierung bezeichnet die Nutzung großer Datenmengen, die zu einer umfassenden Vernetzung aller Bereiche der Wirtschaft und Gesellschaft f{\"u}hren wird (BMWi, 2015 und {\"a}hnlich K{\"o}hler/Wollschl{\"a}ger, 2014: 79). Sie umfasst die Erhebung von analogen Informationen („Big Data" in einem engen Sinne; z.B. O´Leary, 2013), ihre Speicherung in einem digitaltechnischen System (lokale Speicherung oder „Cloud Computing" durch die Weiterentwickelung des Internets; z.B. Hashem et al., 2015: 101), die Analyse und Interpretation sowie den Transfer in andere Systeme („Internet der Dinge" bzw. „Internet of Things"; z.B. Ashton, 2009).},
  language  = {de}
}
@inproceedings{PfaffMelcherFranzen2018,
  author    = {Pfaff, Raphael and Melcher, Karin and Franzen, Julian},
  title     = {Rare event simulation to optimise maintenance intervals of safety critical redundant subsystems},
  series = {Proceedings of the European Conference of the PHM Society},
  volume    = {4},
  booktitle = {Proceedings of the European Conference of the PHM Society},
  number    = {1},
  pages     = {1 -- 6},
  year      = {2018},
  language  = {en}
}
@inproceedings{Pfaff2018,
  author    = {Pfaff, Raphael},
  title     = {Railway Challenge 2018 - Ein Wettbewerb f{\"u}r Parkbahn-Lokomotiven},
  series = {Deine Bahn},
  booktitle = {Deine Bahn},
  issn      = {0948-7263},
  pages     = {22 -- 24},
  year      = {2018},
  language  = {de}
}
@article{OttenWeberArent2018,
  author    = {Otten, Dennis and Weber, Tobias and Arent, Jan-Christoph},
  title     = {Manufacturing Process Simulation - On Its Way to Industrial Application},
  series = {International Journal of Aviation, Aeronautics, and Aerospace},
  volume    = {5},
  journal   = {International Journal of Aviation, Aeronautics, and Aerospace},
  number    = {2},
  publisher = {Embry-Riddle Aeronautical University},
  address   = {Daytona Beach, Fla.},
  issn      = {2374-6793},
  doi       = {10.15394/ijaaa.2018.1217},
  year      = {2018},
  abstract  = {Manufacturing process simulation (MPS) has become more and more important for aviation and the automobile industry. A highly competitive market requires the use of high performance metals and composite materials in combination with reduced manufacturing cost and time as well as a minimization of the time to market for a new product. However, the use of such materials is expensive and requires sophisticated manufacturing processes. An experience based process and tooling design followed by a lengthy trial-and-error optimization is just not contemporary anymore. Instead, a tooling design process aided by simulation is used more often. This paper provides an overview of the capabilities of MPS in the fields of sheet metal forming and prepreg autoclave manufacturing of composite parts summarizing the resulting benefits for tooling design and manufacturing engineering. The simulation technology is explained briefly in order to show several simplification and optimization techniques for developing industrialized simulation approaches. Small case studies provide examples of an efficient application on an industrial scale.},
  language  = {en}
}
@article{Olbertz2018,
  author    = {Olbertz, Klaus},
  title     = {{\"U}berwachung von Arbeitnehmern als Ausdruck von Compliance - Grunds{\"a}tze sowie Zul{\"a}ssigkeit und Grenzen einzelner Maßnahmen},
  series = {NWB - Steuer- und Wirtschaftsrecht},
  journal   = {NWB - Steuer- und Wirtschaftsrecht},
  number    = {21},
  publisher = {NWB-Verl.},
  address   = {Herne},
  issn      = {1860-9449},
  pages     = {1547 -- 1555},
  year      = {2018},
  language  = {de}
}
@article{Olbertz2018,
  author    = {Olbertz, Klaus},
  title     = {Das rechtssichere Arbeitszeugnis - Erlaubte und nicht erlaubte Formulierungen und anderes Wissenswertes},
  series = {NWB - Steuer- und Wirtschaftsrecht},
  journal   = {NWB - Steuer- und Wirtschaftsrecht},
  number    = {12},
  publisher = {NWB-Verl.},
  address   = {Herne},
  issn      = {1860-9449},
  pages     = {802 -- 813},
  year      = {2018},
  language  = {de}
}
@article{Olbertz2018,
  author    = {Olbertz, Klaus},
  title     = {Der Interimsmanager als Selbst{\"a}ndiger oder Arbeitnehmer : Vertragliche Varianten des Interimsmanagements im Faktencheck},
  series = {NWB - Steuer- und Wirtschaftsrecht},
  journal   = {NWB - Steuer- und Wirtschaftsrecht},
  number    = {31},
  publisher = {NWB-Verl.},
  address   = {Herne},
  issn      = {1860-9449},
  pages     = {2260 -- 2266},
  year      = {2018},
  language  = {de}
}
@article{Olbertz2018,
  author    = {Olbertz, Klaus},
  title     = {Bindung des Betriebserwerbers an zuk{\"u}nftige Tariflohnerh{\"o}hungen : Auswirkungen eines Betriebs{\"u}bergangs auf Bezugnahmeklauseln in {\"u}bernommenen Arbeitsvertr{\"a}gen},
  series = {NWB - Steuer- und Wirtschaftsrecht},
  journal   = {NWB - Steuer- und Wirtschaftsrecht},
  number    = {39},
  publisher = {NWB-Verl.},
  address   = {Herne},
  issn      = {1860-9449},
  pages     = {2864 -- 2869},
  year      = {2018},
  language  = {de}
}
@article{OberlaenderMayerGreeffetal.2018,
  author    = {Oberl{\"a}nder, Jan and Mayer, Marlena and Greeff, Anton and Keusgen, Michael and Sch{\"o}ning, Michael Josef},
  title     = {Spore-based biosensor to monitor the microbicidal efficacy of gaseous hydrogen peroxide sterilization processes},
  series = {Biosensors and Bioelectronics},
  volume    = {104},
  journal   = {Biosensors and Bioelectronics},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0956-5663},
  doi       = {10.1016/j.bios.2017.12.045},
  pages     = {87 -- 94},
  year      = {2018},
  abstract  = {In this work, a spore-based biosensor is evaluated to monitor the microbicidal efficacy of sterilization processes applying gaseous hydrogen peroxide (H2O2). The sensor is based on interdigitated electrode structures (IDEs) that have been fabricated by means of thin-film technologies. Impedimetric measurements are applied to study the effect of sterilization process on spores of Bacillus atrophaeus. This resilient microorganism is commonly used in industry to proof the sterilization efficiency. The sensor measurements are accompanied by conventional microbiological challenge tests, as well as morphological characterizations with scanning electron microscopy (SEM) and transmission electron microscopy (TEM). The sensor measurements are correlated with the microbiological test routines. In both methods, namely the sensor-based and microbiological one, a tailing effect has been observed. The results are evaluated and discussed in a three-dimensional calibration plot demonstrating the sensor's suitability to enable a rapid process decision in terms of a successfully performed sterilization.},
  language  = {en}
}
@inproceedings{MuellerAbdelrazeqBraunerCaleroValdezetal.2018,
  author    = {M{\"u}ller-Abdelrazeq, Sarah Luisa and Brauner, Philipp and Calero Valdez, Andr{\´e} and Jansen, Ulrich and Platte, Laura and Schaar, Anne-Kathrin and Steuer-Dankert, Linda and Zachow, Sebastian and Sch{\"o}nefeld, Kathrin and Haberstroh, Max and Leicht-Scholten, Carmen and Ziefle, Martina},
  title     = {Interdisciplinary cooperation management in research clusters: a review of twelve years.},
  series = {Proceedings of the 15th International Conference on Intellectual Capital, Knowledge Management \& Organisational Learning},
  booktitle = {Proceedings of the 15th International Conference on Intellectual Capital, Knowledge Management \& Organisational Learning},
  editor    = {Pather, Shaun},
  publisher = {ACPIL},
  isbn      = {978-1-912764-09-9},
  pages     = {216 -- 224},
  year      = {2018},
  abstract  = {As an interdisciplinary research network, the Cluster of Excellence "Integrative Production Technology for High-Wage Countries" (CoE) comprises of around 150 researchers. Their scientific background ranges from mechanical engineering and computer science to social sciences such as sociology and psychology. In addition to content- and methodbased challenges, the CoE's employees are faced with heterogenic organizational cultures, different hierarchical levels, an imbalanced gender distribution, and a high employee fluctuation. The sub-project Scientific Cooperation Engineering 1 (CSP1) addresses the challenge of interdisciplinary cooperation and organizational learning and aims at fostering interdisciplinarity and its synergies as a source of innovation. Therefore, the project examines means of reaching an organizational development, ranging from temporal structures to a sustainable network in production technology. To achieve this aim, a broad range of means has been developed during the last twelve years: In addition to physical measures such as regular network events and trainings, virtual measures such as the Terminology App were focused. The app is an algorithmic analysis method for uncovering latent topic structures of publications of the CoE to highlight thematic intersections and synergy potentials. The detection and promotion of has been a vital and long known element in knowledge management. Furthermore, CSP1 focusses on project management and thus developed evaluation tools to measure and control the success of interdisciplinary cooperation. In addition to the cooperation fostering measures, CSP1 conducted studies about interdisciplinarity and diversity and their relationship with innovation. The scientific background of these means and the research results of CSP1 are outlined in this paper to offer approaches for successful interdisciplinary cooperation management.},
  language  = {en}
}
@incollection{MuellerAltherrAholaetal.2018,
  author    = {M{\"u}ller, Tim M. and Altherr, Lena and Ahola, Marja and Schabel, Samuel and Pelz, Peter F.},
  title     = {Optimizing pressure screen systems in paper recycling: optimal system layout, component selection and operation},
  publisher = {Springer},
  address   = {Cham},
  isbn      = {978-3-030-18499-5},
  doi       = {10.1007/978-3-030-18500-8_44},
  pages     = {355 -- 361},
  year      = {2018},
  abstract  = {Around 60\% of the paper worldwide is made from recovered paper. Especially adhesive contaminants, so called stickies, reduce paper quality. To remove stickies but at the same time keep as many valuable fibers as possible, multi-stage screening systems with several interconnected pressure screens are used. When planning such systems, suitable screens have to be selected and their interconnection as well as operational parameters have to be defined considering multiple conflicting objectives. In this contribution, we present a Mixed-Integer Nonlinear Program to optimize system layout, component selection and operation to find a suitable trade-off between output quality and yield.},
  language  = {en}
}
@article{MuellerBeckersMussmannetal.2018,
  author    = {M{\"u}ller, Janina and Beckers, Mario and Mußmann, Nina and Bongaerts, Johannes and B{\"u}chs, Jochen},
  title     = {Elucidation of auxotrophic deficiencies of Bacillus pumilus DSM 18097 to develop a defined minimal medium},
  series = {Microbial Cell Factories},
  volume    = {17},
  journal   = {Microbial Cell Factories},
  number    = {1},
  publisher = {BioMed Central},
  issn      = {1475-2859},
  doi       = {10.1186/s12934-018-0956-1},
  pages     = {Article No. 106},
  year      = {2018},
  abstract  = {Background Culture media containing complex compounds like yeast extract or peptone show numerous disadvantages. The chemical composition of the complex compounds is prone to significant variations from batch to batch and quality control is difficult. Therefore, the use of chemically defined media receives more and more attention in commercial fermentations. This concept results in better reproducibility, it simplifies downstream processing of secreted products and enable rapid scale-up. Culturing bacteria with unknown auxotrophies in chemically defined media is challenging and often not possible without an extensive trial-and-error approach. In this study, a respiration activity monitoring system for shake flasks and its recent version for microtiter plates were used to clarify unknown auxotrophic deficiencies in the model organism Bacillus pumilus DSM 18097. Results Bacillus pumilus DSM 18097 was unable to grow in a mineral medium without the addition of complex compounds. Therefore, a rich chemically defined minimal medium was tested containing basically all vitamins, amino acids and nucleobases, which are essential ingredients of complex components. The strain was successfully cultivated in this medium. By monitoring of the respiration activity, nutrients were supplemented to and omitted from the rich chemically defined medium in a rational way, thus enabling a systematic and fast determination of the auxotrophic deficiencies. Experiments have shown that the investigated strain requires amino acids, especially cysteine or histidine and the vitamin biotin for growth. Conclusions The introduced method allows an efficient and rapid identification of unknown auxotrophic deficiencies and can be used to develop a simple chemically defined tailor-made medium. B. pumilus DSM 18097 was chosen as a model organism to demonstrate the method. However, the method is generally suitable for a wide range of microorganisms. By combining a systematic combinatorial approach based on monitoring the respiration activity with cultivation in microtiter plates, high throughput experiments with high information content can be conducted. This approach facilitates media development, strain characterization and cultivation of fastidious microorganisms in chemically defined minimal media while simultaneously reducing the experimental effort.},
  language  = {en}
}
@article{MolinnusMuschallikGonzalezetal.2018,
  author    = {Molinnus, Denise and Muschallik, Lukas and Gonzalez, Laura Osorio and Bongaerts, Johannes and Wagner, Torsten and Selmer, Thorsten and Siegert, Petra and Keusgen, Michael and Sch{\"o}ning, Michael Josef},
  title     = {Development and characterization of a field-effect biosensor for the detection of acetoin},
  series = {Biosensors and Bioelectronics},
  volume    = {115},
  journal   = {Biosensors and Bioelectronics},
  publisher = {Elsevier},
  address   = {Amsterdam},
  doi       = {10.1016/j.bios.2018.05.023},
  pages     = {1 -- 6},
  year      = {2018},
  abstract  = {A capacitive electrolyte-insulator-semiconductor (EIS) field-effect biosensor for acetoin detection has been presented for the first time. The EIS sensor consists of a layer structure of Al/p-Si/SiO₂/Ta₂O₅/enzyme acetoin reductase. The enzyme, also referred to as butane-2,3-diol dehydrogenase from B. clausii DSM 8716T, has been recently characterized. The enzyme catalyzes the (R)-specific reduction of racemic acetoin to (R,R)- and meso-butane-2,3-diol, respectively. Two different enzyme immobilization strategies (cross-linking by using glutaraldehyde and adsorption) have been studied. Typical biosensor parameters such as optimal pH working range, sensitivity, hysteresis, linear concentration range and long-term stability have been examined by means of constant-capacitance (ConCap) mode measurements. Furthermore, preliminary experiments have been successfully carried out for the detection of acetoin in diluted white wine samples.},
  language  = {en}
}
@article{MolinnusHardtSiegertetal.2018,
  author    = {Molinnus, Denise and Hardt, Gabriel and Siegert, Petra and Willenberg, Holger S. and Poghossian, Arshak and Keusgen, Michael and Sch{\"o}ning, Michael Josef},
  title     = {Detection of Adrenaline in Blood Plasma as Biomarker for Adrenal Venous Sampling},
  series = {Electroanalysis},
  volume    = {30},
  journal   = {Electroanalysis},
  number    = {5},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {1521-4109},
  doi       = {10.1002/elan.201800026},
  pages     = {937 -- 942},
  year      = {2018},
  abstract  = {An amperometric bi-enzyme biosensor based on substrate recycling principle for the amplification of the sensor signal has been developed for the detection of adrenaline in blood. Adrenaline can be used as biomarker verifying successful adrenal venous sampling procedure. The adrenaline biosensor has been realized via modification of a galvanic oxygen sensor with a bi-enzyme membrane combining a genetically modified laccase and a pyrroloquinoline quinone-dependent glucose dehydrogenase. The measurement conditions such as pH value and temperature were optimized to enhance the sensor performance. A high sensitivity and a low detection limit of about 0.5-1 nM adrenaline have been achieved in phosphate buffer at pH 7.4, relevant for measurements in blood samples. The sensitivity of the biosensor to other catecholamines such as noradrenaline, dopamine and dobutamine has been studied. Finally, the sensor has been successfully applied for the detection of adrenaline in human blood plasma.},
  language  = {en}
}
@article{MolinnusHardtKaeveretal.2018,
  author    = {Molinnus, Denise and Hardt, G. and K{\"a}ver, L. and Willenberg, H.S. and Kr{\"o}ger, J.-C. and Poghossian, Arshak and Keusgen, Michael and Sch{\"o}ning, Michael Josef},
  title     = {Chip-based biosensor for the detection of low adrenaline concentrations to support adrenal venous sampling},
  series = {Sensor and Actuators B: Chemical},
  volume    = {272},
  journal   = {Sensor and Actuators B: Chemical},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0925-4005},
  doi       = {10.1016/j.snb.2018.05.136},
  pages     = {21 -- 27},
  year      = {2018},
  abstract  = {A chip-based amperometric biosensor referring on using the bioelectrocatalytical amplification principle for the detection of low adrenaline concentrations is presented. The adrenaline biosensor has been prepared by modification of a platinum thin-film electrode with an enzyme membrane containing the pyrroloquinoline quinone-dependent glucose dehydrogenase and glutaraldehyde. Measuring conditions such as temperature, pH value, and glucose concentration have been optimized to achieve a high sensitivity and a low detection limit of about 1 nM adrenaline measured in phosphate buffer at neutral pH value. The response of the biosensor to different catecholamines has also been proven. Long-term stability of the adrenaline biosensor has been studied over 10 days. In addition, the biosensor has been successfully applied for adrenaline detection in human blood plasma for future biomedical applications. Furthermore, preliminary experiments have been carried to detect the adrenaline-concentration difference measured in peripheral blood and adrenal venous blood, representing the adrenal vein sampling procedure of a physician.},
  language  = {en}
}
@book{Molinnus2018,
  author    = {Molinnus, Denise},
  title     = {Integration of biomolecular logic principles with electronic transducers on a chip},
  publisher = {Philipps-Universit{\"a}t / Fachbereich Pharmazie},
  address   = {Marburg/Lahn},
  year      = {2018},
  language  = {de}
}
@article{MiyamotoSekiSutoetal.2018,
  author    = {Miyamoto, Koichiro and Seki, Kosuke and Suto, Takeyuki and Werner, Frederik and Wagner, Torsten and Sch{\"o}ning, Michael Josef and Yoshinobu, Tatsuo},
  title     = {Improved spatial resolution of the chemical imaging sensor with a hybrid illumination that suppresses lateral diffusion of photocarriers},
  series = {Sensor and Actuators B: Chemical},
  volume    = {273},
  journal   = {Sensor and Actuators B: Chemical},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0925-4005},
  doi       = {10.1016/j.snb.2018.07.016},
  pages     = {1328 -- 1333},
  year      = {2018},
  abstract  = {The chemical imaging sensor is a semiconductor-based chemical sensor capable of visualizing pH and ion distributions. The spatial resolution depends on the lateral diffusion of photocarriers generated by illumination of the semiconductor substrate. In this study, two types of optical setups, one based on a bundle of optical fibers and the other based on a binocular tube head, were developed to project a hybrid illumination of a modulated light beam and a ring-shaped constant illumination onto the sensor plate. An improved spatial resolution was realized by the ring-shaped constant illumination, which suppressed lateral diffusion of photocarriers by enhanced recombination due to the increased carrier concentration.},
  language  = {en}
}
@inproceedings{MilkovaRosinButenwegetal.2018,
  author    = {Milkova, Kristina and Rosin, Julia and Butenweg, Christoph and Dumova-Jovanoska, Elena},
  title     = {Development of Seismic Vulnerability Curves for Region Specific Masonry Buildings},
  series = {16th European Conference on Earthquake Engineering, Thessaloniki, 18-21 June, 2018},
  booktitle = {16th European Conference on Earthquake Engineering, Thessaloniki, 18-21 June, 2018},
  pages     = {1 -- 10},
  year      = {2018},
  language  = {en}
}
@inproceedings{MichelButenwegKlinkel2018,
  author    = {Michel, Philipp and Butenweg, Christoph and Klinkel, Sven},
  title     = {Frequency Dependent Impedance Analysis of the Foundation-Soil-Systems of Onshore Wind Turbines},
  series = {16th European Conference on Earthquake Engineering, Thessaloniki, 18-21 June, 2018},
  booktitle = {16th European Conference on Earthquake Engineering, Thessaloniki, 18-21 June, 2018},
  pages     = {1 -- 13},
  year      = {2018},
  language  = {en}
}
@article{MichelButenwegKinkel2018,
  author    = {Michel, Philipp and Butenweg, Christoph and Kinkel, Sven},
  title     = {Pile-grid foundations of onshore wind turbines considering soil-structure-interaction under seismic loading},
  series = {Soil Dynamics and Earthquake Engineering},
  volume    = {109},
  journal   = {Soil Dynamics and Earthquake Engineering},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0267-7261},
  doi       = {10.1016/j.soildyn.2018.03.009},
  pages     = {299 -- 311},
  year      = {2018},
  abstract  = {In recent years, many onshore wind turbines are erected in seismic active regions and on soils with poor load bearing capacity, where pile grids are inevitable to transfer the loads into the ground. In this contribution, a realistic multi pile grid is designed to analyze the dynamics of a wind turbine tower including frequency dependent soil-structure-interaction. It turns out that different foundations on varying soil configurations heavily influence the vibration response. While the vibration amplitude is mostly attenuated, certain unfavorable combinations of structure and soil parameters lead to amplification in the range of the system's natural frequencies. This testifies the need for overall dynamic analysis in the assessment of the dynamic stability and the holistic frequency tuning of the turbines.},
  language  = {en}
}
@article{MichauxMatternKallweit2018,
  author    = {Michaux, F. and Mattern, P. and Kallweit, Stephan},
  title     = {RoboPIV: how robotics enable PIV on a large industrial scale},
  series = {Measurement Science and Technology},
  volume    = {29},
  journal   = {Measurement Science and Technology},
  number    = {7},
  publisher = {IOP},
  address   = {Bristol},
  issn      = {1361-6501},
  doi       = {10.1088/1361-6501/aab5c1},
  pages     = {074009},
  year      = {2018},
  abstract  = {This work demonstrates how the interaction between particle image velocimetry (PIV) and robotics can massively increase measurement efficiency. The interdisciplinary approach is shown using the complex example of an automated, large scale, industrial environment: a typical automotive wind tunnel application. Both the high degree of flexibility in choosing the measurement region and the complete automation of stereo PIV measurements are presented. The setup consists of a combination of three robots, individually used as a 6D traversing unit for the laser illumination system as well as for each of the two cameras. Synchronised movements in the same reference frame are realised through a master-slave setup with a single interface to the user. By integrating the interface into the standard wind tunnel management system, a single measurement plane or a predefined sequence of several planes can be requested through a single trigger event, providing the resulting vector fields within minutes. In this paper, a brief overview on the demands of large scale industrial PIV and the existing solutions is given. Afterwards, the concept of RoboPIV is introduced as a new approach. In a first step, the usability of a selection of commercially available robot arms is analysed. The challenges of pose uncertainty and importance of absolute accuracy are demonstrated through comparative measurements, explaining the individual pros and cons of the analysed systems. Subsequently, the advantage of integrating RoboPIV directly into the existing wind tunnel management system is shown on basis of a typical measurement sequence. In a final step, a practical measurement procedure, including post-processing, is given by using real data and results. Ultimately, the benefits of high automation are demonstrated, leading to a drastic reduction in necessary measurement time compared to non-automated systems, thus massively increasing the efficiency of PIV measurements.},
  language  = {en}
}
@article{MatchaLjubasGueldemet2018,
  author    = {Matcha, Heike and Ljubas, Ante and Gueldemet, Harun},
  title     = {Printing a Coffee Bar: An investigation into mid-scale 3D printing},
  series = {Computing for a better tomorrow - Proceedings of the 36th eCAADe Conference - Volume 2, Lodz University of Technology, Lodz, Poland, 19-21 September 2018},
  journal   = {Computing for a better tomorrow - Proceedings of the 36th eCAADe Conference - Volume 2, Lodz University of Technology, Lodz, Poland, 19-21 September 2018},
  editor    = {Kepczynska-Walczak, A.},
  pages     = {59 -- 68},
  year      = {2018},
  abstract  = {We present and discuss an exploration of the possibilities and properties of 3D printing with a printing space of 1 cubic meter, and how those can be integrated into architectural education through an experimental design and research course with students of architecture.We expand on issues presented at the eCAADe conference 2017 in Rome [Ref 6] by increasing the complexity and size of our prints, printing not a model to scale, but a full scale funtional prototype of a usable architectural object: A coffee bar.},
  language  = {en}
}
@inproceedings{MarinkovicButenweg2018,
  author    = {Marinkovic, Marko and Butenweg, Christoph},
  title     = {Innovative System for Earthquake Resistant Masonry Infill Walls},
  series = {16th European Conference on Earthquake Engineering, Thessaloniki, 18-21 June, 2018},
  booktitle = {16th European Conference on Earthquake Engineering, Thessaloniki, 18-21 June, 2018},
  pages     = {1 -- 12},
  year      = {2018},
  language  = {en}
}
@inproceedings{LudowicyRingsFingeretal.2018,
  author    = {Ludowicy, Jonas and Rings, Ren{\´e} and Finger, Felix and Braun, Carsten},
  title     = {Sizing Studies of Light Aircraft with Serial Hybrid Propulsion Systems},
  series = {Luft- und Raumfahrt - Digitalisierung und Vernetzung : Deutscher Luft- und Raumfahrtkongress 2018. 4. - 6. September 2018 - Friedrichshafen},
  booktitle = {Luft- und Raumfahrt - Digitalisierung und Vernetzung : Deutscher Luft- und Raumfahrtkongress 2018. 4. - 6. September 2018 - Friedrichshafen},
  pages     = {11 S.},
  year      = {2018},
  language  = {en}
}
@inproceedings{LudowicyRingsFingeretal.2018,
  author    = {Ludowicy, Jonas and Rings, Ren{\´e} and Finger, Felix and Braun, Carsten},
  title     = {Sizing Studies of Light Aircraft with Parallel Hybrid Propulsion Systems},
  series = {Deutscher Luft- und Raumfahrtkongress 2018},
  booktitle = {Deutscher Luft- und Raumfahrtkongress 2018},
  doi       = {10.25967/480227},
  pages     = {15 S.},
  year      = {2018},
  language  = {en}
}
@article{Lind2018,
  author    = {Lind, Thorsten Patric},
  title     = {Neues zur Gesch{\"a}ftsf{\"u}hrerhaftung nach \S 64 GmbHG - Zugleich Anmerkung zu BGH vom 19.12.2017 - II ZR 88/16, DB 2018 S. 307, und vom 04.07.2017 - II ZR 319/15, DB 2017 S. 1959 -},
  series = {Der Betrieb},
  journal   = {Der Betrieb},
  number    = {17},
  publisher = {Fachmedien Otto Schmidt},
  address   = {D{\"u}sseldorf},
  issn      = {0005-9935},
  pages     = {1003 -- 1008},
  year      = {2018},
  language  = {de}
}
@misc{Lind2018,
  author    = {Lind, Thorsten Patric},
  title     = {Antrag auf L{\"o}schung von Insolvenzvermerken bei Insolvenz eines GbR-Gesellschafters},
  series = {Fachdienst Zivilrecht - LMK - Kommentierte BGH-Rechtsprechung, Lindenmaier-M{\"o}hring},
  journal   = {Fachdienst Zivilrecht - LMK - Kommentierte BGH-Rechtsprechung, Lindenmaier-M{\"o}hring},
  issn      = {1611-1095},
  year      = {2018},
  language  = {de}
}
@inproceedings{LeiseAltherrPelz2018,
  author    = {Leise, Philipp and Altherr, Lena and Pelz, Peter F.},
  title     = {Technical Operations Research (TOR) - Algorithms, not Engineers, Design Optimal Energy Efficient and Resilient Cooling Systems},
  series = {FAN2018 - Proceedings of the International Conference on Fan Noise, Aerodynamics, Applications and Systems},
  booktitle = {FAN2018 - Proceedings of the International Conference on Fan Noise, Aerodynamics, Applications and Systems},
  pages     = {1 -- 12},
  year      = {2018},
  abstract  = {The overall energy efficiency of ventilation systems can be improved by considering not only single components, but by considering as well the interplay between every part of the system. With the help of the method "TOR" ("Technical Operations Research"), which was developed at the Chair of Fluid Systems at TU Darmstadt, it is possible to improve the energy efficiency of the whole system by considering all possible design choices programmatically. We show the ability of this systematic design approach with a ventilation system for buildings as a use case example. Based on a Mixed-Integer Nonlinear Program (MINLP) we model the ventilation system. We use binary variables to model the selection of different pipe diameters. Multiple fans are model with the help of scaling laws. The whole system is represented by a graph, where the edges represent the pipes and fans and the nodes represents the source of air for cooling and the sinks, that have to be cooled. At the beginning, the human designer chooses a construction kit of different suitable fans and pipes of different diameters and different load cases. These boundary conditions define a variety of different possible system topologies. It is not possible to consider all topologies by hand. With the help of state of the art solvers, on the other side, it is possible to solve this MINLP. Next to this, we also consider the effects of malfunctions in different components. Therefore, we show a first approach to measure the resilience of the shown example use case. Further, we compare the conventional approach with designs that are more resilient. These more resilient designs are derived by extending the before mentioned model with further constraints, that consider explicitly the resilience of the overall system. We show that it is possible to design resilient systems with this method already in the early design stage and compare the energy efficiency and resilience of these different system designs.},
  language  = {en}
}
@incollection{LeiseAltherrPelz2018,
  author    = {Leise, Philipp and Altherr, Lena and Pelz, Peter F.},
  title     = {Energy-Efficient design of a water supply system for skyscrapers by mixed-integer nonlinear programming},
  series = {Operations Research Proceedings 2017},
  booktitle = {Operations Research Proceedings 2017},
  publisher = {Springer},
  address   = {Cham},
  isbn      = {978-3-319-89919-0},
  doi       = {10.1007/978-3-319-89920-6_63},
  year      = {2018},
  abstract  = {The energy-efficiency of technical systems can be improved by a systematic design approach. Technical Operations Research (TOR) employs methods known from Operations Research to find a global optimal layout and operation strategy of technical systems. We show the practical usage of this approach by the systematic design of a decentralized water supply system for skyscrapers. All possible network options and operation strategies are modeled by a Mixed-Integer Nonlinear Program. We present the optimal system found by our approach and highlight the energy savings compared to a conventional system design.},
  language  = {en}
}
@inproceedings{LeiseAltherr2018,
  author    = {Leise, Philipp and Altherr, Lena},
  title     = {Optimizing the design and control of decentralized water supply systems - a case-study of a hotel building},
  series = {EngOpt 2018 Proceedings of the 6th International Conference on Engineering Optimization},
  booktitle = {EngOpt 2018 Proceedings of the 6th International Conference on Engineering Optimization},
  publisher = {Springer},
  address   = {Cham},
  isbn      = {978-3-319-97773-7},
  doi       = {10.1007/978-3-319-97773-7_107},
  pages     = {1241 -- 1252},
  year      = {2018},
  abstract  = {To increase pressure to supply all floors of high buildings with water, booster stations, normally consisting of several parallel pumps in the basement, are used. In this work, we demonstrate the potential of a decentralized pump topology regarding energy savings in water supply systems of skyscrapers. We present an approach, based on Mixed-Integer Nonlinear Programming, that allows to choose an optimal network topology and optimal pumps from a predefined construction kit comprising different pump types. Using domain-specific scaling laws and Latin Hypercube Sampling, we generate different input sets of pump types and compare their impact on the efficiency and cost of the total system design. As a realistic application example, we consider a hotel building with 325 rooms, 12 floors and up to four pressure zones.},
  language  = {en}
}
@article{LauraDrechslerErdtetal.2018,
  author    = {Laura, C.O. and Drechsler, Klaus and Erdt, M. and Wesarg, S. and Bale, R.},
  title     = {Intervention assessment tool for primary tumors in the liver},
  series = {Current Directions in Biomedical Engineering},
  volume    = {4},
  journal   = {Current Directions in Biomedical Engineering},
  number    = {1},
  publisher = {De Gruyter},
  address   = {Berlin},
  issn      = {2364-5504},
  doi       = {10.1515/cdbme-2018-0081},
  pages     = {337 -- 340},
  year      = {2018},
  abstract  = {After a liver tumor intervention the medical doctor has to compare both pre and postoperative CT acquisitions to ensure that all carcinogenic cells are destroyed. A correct assessment of the intervention is of vital importance, since it will reduce the probability of tumor recurrence. Some methods have been proposed to support the medical doctors during the assessment process, however, all of them focus on secondary tumors. In this paper a tool is presented that enables the outcome validation for both primary and secondary tumors. Therefore, a multiphase registration (preoperative arterial and portal phases) followed by a registration between the pre and postoperative CT images is carried out. The first registration is in charge of the primary tumors that are only visible in the arterial phase. The secondary tumors will be incorporated in the second registration step. Finally, the part of the tumor that was not covered by the necrosis is quantified and visualized. The method has been tested in 9 patients, with an average registration error of 1.41 mm.},
  language  = {en}
}
@article{LapitanRogatkinPersheyevetal.2018,
  author    = {Lapitan, Denis G. and Rogatkin, Dmitrii A. and Persheyev, Sydulla K. and Kotliar, Konstantin},
  title     = {False spectra formation in the differential two-channel scheme of the laser Doppler flowmeter},
  series = {Biomedizinische Technik},
  volume    = {63},
  journal   = {Biomedizinische Technik},
  number    = {4},
  publisher = {De Gruyter},
  address   = {Berlin},
  issn      = {0013-5585},
  doi       = {10.1515/bmt-2017-0060},
  pages     = {439 -- 444},
  year      = {2018},
  abstract  = {Noise in the differential two-channel scheme of a classic laser Doppler flowmetry (LDF) instrument was studied. Formation of false spectral components in the output signal due to beating of electrical signals in the differential amplifier was found out. The improved block-diagram of the flowmeter was developed allowing to reduce the noise.},
  language  = {en}
}
@book{Laack2018,
  author    = {Laack, Walter van},
  title     = {Sterben und Tod aus wissenschaftlicher Sicht - dying and death from a scientific point of view},
  publisher = {van Laack GmbH},
  address   = {Aachen},
  isbn      = {978-3-936624-41-0},
  pages     = {44 Seiten},
  year      = {2018},
  language  = {de}
}
@article{KoenigWolf2018,
  author    = {K{\"o}nig, Johannes Alexander and Wolf, Martin},
  title     = {GHOST: An Evaluated Competence Developing Game for Cybersecurity Awareness Training},
  series = {International Journal on Advances in Security},
  volume    = {11},
  journal   = {International Journal on Advances in Security},
  number    = {3 \& 4},
  publisher = {IARIA Journals},
  issn      = {1942-2636},
  pages     = {274 -- 287},
  year      = {2018},
  abstract  = {To train end users how to interact with digital systems is indispensable to ensure a strong computer security. 'Competence Developing Game'-based approaches are particularly suitable for this purpose because of their motivation-and simulation-aspects. In this paper the Competence Developing Game 'GHOST' for cybersecurity awareness trainings and its underlying patterns are described. Accordingly, requirements for an 'Competence Developing Game' based training are discussed. Based on these requirements it is shown how a game can fulfill these requirements. A supplementary game interaction design and a corresponding evaluation study is shown. The combination of training requirements and interaction design is used to create a 'Competence Developing Game'-based training concept. A part of these concept is implemented into a playable prototype that serves around one hour of play respectively training time. This prototype is used to perform an evaluation of the game and training aspects of the awareness training. Thereby, the quality of the game aspect and the effectiveness of the training aspect are shown.},
  language  = {en}
}