@article{BronderPoghossianKeusgenetal.2017, author = {Bronder, Thomas and Poghossian, Arshak and Keusgen, Michael and Sch{\"o}ning, Michael Josef}, title = {Label-free detection of double-stranded DNA molecules with polyelectrolyte-modified capacitive field-effect sensors}, series = {tm - Technisches Messen}, volume = {84}, journal = {tm - Technisches Messen}, number = {10}, publisher = {De Gruyter}, address = {Oldenbourg}, doi = {10.1515/teme-2017-0015}, pages = {628 -- 634}, year = {2017}, abstract = {In this study, polyelectrolyte-modified field-effect-based electrolyte-insulator-semiconductor (EIS) devices have been used for the label-free electrical detection of double-stranded deoxyribonucleic acid (dsDNA)molecules. The sensor-chip functionalization with a positively charged polyelectrolyte layer provides the possibility of direct adsorptive binding of negatively charged target DNA oligonucleotides onto theSiO2-chip surface.EIS sensors can be utilized as a tool to detect surface-charge changes; the electrostatic adsorption of oligonucleotides onto the polyelectrolyte layer leads to a measureable surface-potential change. Signals of 39mV have been recorded after the incubation with the oligonucleotide solution. Besides the electrochemical experiments, the successful adsorption of dsDNA onto the polyelectrolyte layer has been verified via fluorescence microscopy. The presented results demonstrate that the signal recording of EISchips, which are modified with a polyelectrolyte layer, canbe used as a favorable approach for a fast, cheap and simple detection method for dsDNA.}, language = {en} } @article{BronderPoghossianJessingetal.2019, author = {Bronder, Thomas and Poghossian, Arshak and Jessing, Max P. and Keusgen, Michael and Sch{\"o}ning, Michael Josef}, title = {Surface regeneration and reusability of label-free DNA biosensors based on weak polyelectrolyte-modified capacitive field-effect structures}, series = {Biosensors and Bioelectronics}, volume = {126}, journal = {Biosensors and Bioelectronics}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0956-5663}, doi = {10.1016/j.bios.2018.11.019}, pages = {510 -- 517}, year = {2019}, language = {en} } @article{BronderJessingPoghossianetal.2018, author = {Bronder, Thomas and Jessing, Max P. and Poghossian, Arshak and Keusgen, Michael and Sch{\"o}ning, Michael Josef}, title = {Detection of PCR-Amplified Tuberculosis DNA Fragments with Polyelectrolyte-Modified Field-Effect Sensors}, series = {Analytical Chemistry}, volume = {90}, journal = {Analytical Chemistry}, number = {12}, publisher = {ACS Publications}, address = {Washington, DC}, issn = {0003-2700}, doi = {10.1021/acs.analchem.8b01807}, pages = {7747 -- 7753}, year = {2018}, abstract = {Field-effect-based electrolyte-insulator-semiconductor (EIS) sensors were modified with a bilayer of positively charged weak polyelectrolyte (poly(allylamine hydrochloride) (PAH)) and probe single-stranded DNA (ssDNA) and are used for the detection of complementary single-stranded target DNA (cDNA) in different test solutions. The sensing mechanism is based on the detection of the intrinsic molecular charge of target cDNA molecules after the hybridization event between cDNA and immobilized probe ssDNA. The test solutions contain synthetic cDNA oligonucleotides (with a sequence of tuberculosis mycobacteria genome) or PCR-amplified DNA (which origins from a template DNA strand that has been extracted from Mycobacterium avium paratuberculosis-spiked human sputum samples), respectively. Sensor responses up to 41 mV have been measured for the test solutions with DNA, while only small signals of ∼5 mV were detected for solutions without DNA. The lower detection limit of the EIS sensors was ∼0.3 nM, and the sensitivity was ∼7.2 mV/decade. Fluorescence experiments using SybrGreen I fluorescence dye support the electrochemical results.}, language = {en} } @article{BrockhausBehbahaniMurisetal.2021, author = {Brockhaus, Moritz K. and Behbahani, Mehdi and Muris, Farina and Jansen, Sebastian V. and Schmitz- Rode, Thomas and Steinseifer, Ulrich and Clauser, Johanna C.}, title = {In vitro thrombogenicity testing of pulsatile mechanical circulatory support systems: Design and proof-of-concept}, series = {Artificial Organs}, volume = {45}, journal = {Artificial Organs}, number = {12}, publisher = {Wiley}, address = {Weinheim}, issn = {1525-1594}, doi = {10.1111/aor.14046}, pages = {1513 -- 1521}, year = {2021}, abstract = {Thrombogenic complications are a main issue in mechanical circulatory support (MCS). There is no validated in vitro method available to quantitatively assess the thrombogenic performance of pulsatile MCS devices under realistic hemodynamic conditions. The aim of this study is to propose a method to evaluate the thrombogenic potential of new designs without the use of complex in-vivo trials. This study presents a novel in vitro method for reproducible thrombogenicity testing of pulsatile MCS systems using low molecular weight heparinized porcine blood. Blood parameters are continuously measured with full blood thromboelastometry (ROTEM; EXTEM, FIBTEM and a custom-made analysis HEPNATEM). Thrombus formation is optically observed after four hours of testing. The results of three experiments are presented each with two parallel loops. The area of thrombus formation inside the MCS device was reproducible. The implantation of a filter inside the loop catches embolizing thrombi without a measurable increase of platelet activation, allowing conclusions of the place of origin of thrombi inside the device. EXTEM and FIBTEM parameters such as clotting velocity (α) and maximum clot firmness (MCF) show a total decrease by around 6\% with a characteristic kink after 180 minutes. HEPNATEM α and MCF rise within the first 180 minutes indicate a continuously increasing activation level of coagulation. After 180 minutes, the consumption of clotting factors prevails, resulting in a decrease of α and MCF. With the designed mock loop and the presented protocol we are able to identify thrombogenic hot spots inside a pulsatile pump and characterize their thrombogenic potential.}, language = {en} } @article{BreussKleefeld2020, author = {Breuß, Michael and Kleefeld, Andreas}, title = {Implicit monotone difference methods for scalar conservation laws with source terms}, series = {Acta Mathematica Vietnamica}, volume = {45}, journal = {Acta Mathematica Vietnamica}, publisher = {Springer Singapore}, address = {Singapore}, issn = {2315-4144}, doi = {10.1007/s40306-019-00354-1}, pages = {709 -- 738}, year = {2020}, abstract = {In this article, a concept of implicit methods for scalar conservation laws in one or more spatial dimensions allowing also for source terms of various types is presented. This material is a significant extension of previous work of the first author (Breuß SIAM J. Numer. Anal. 43(3), 970-986 2005). Implicit notions are developed that are centered around a monotonicity criterion. We demonstrate a connection between a numerical scheme and a discrete entropy inequality, which is based on a classical approach by Crandall and Majda. Additionally, three implicit methods are investigated using the developed notions. Next, we conduct a convergence proof which is not based on a classical compactness argument. Finally, the theoretical results are confirmed by various numerical tests.}, language = {en} } @article{BreuerRaueStrobeletal.2016, author = {Breuer, Lars and Raue, Markus and Strobel, M. and Mang, Thomas and Sch{\"o}ning, Michael Josef and Thoelen, R. and Wagner, Torsten}, title = {Hydrogels with incorporated graphene oxide as light-addressable actuator materials for cell culture environments in lab-on-chip systems}, series = {Physica status solidi (a)}, volume = {213}, journal = {Physica status solidi (a)}, number = {6}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {1862-6300}, doi = {10.1002/pssa.201533056}, pages = {1520 -- 1525}, year = {2016}, abstract = {Abstractauthoren Graphene oxide (GO) nanoparticles were incorporated in temperature-sensitive Poly(N-isopropylacrylamide) (PNIPAAm) hydrogels. The nanoparticles increase the light absorption and convert light energy into heat efficiently. Thus, the hydrogels with GO can be stimulated spatially resolved by illumination as it was demonstrated by IR thermography. The temporal progression of the temperature maximum was detected for different concentrations of GO within the polymer network. Furthermore, the compatibility of PNIPAAm hydrogels with GO and cell cultures was investigated. For this purpose, culture medium was incubated with hydrogels containing GO and the viability and morphology of chinese hamster ovary (CHO) cells was examined after several days of culturing in presence of this medium.}, language = {en} } @article{BreuerRaueKirschbaumetal.2015, author = {Breuer, Lars and Raue, Markus and Kirschbaum, M. and Mang, Thomas and Sch{\"o}ning, Michael Josef and Thoelen, R. and Wagner, Torsten}, title = {Light-controllable polymeric material based on temperature-sensitive hydrogels with incorporated graphene oxide}, series = {Physica status solidi (a)}, volume = {212}, journal = {Physica status solidi (a)}, number = {6}, publisher = {Wiley}, address = {Weinheim}, issn = {1862-6319}, doi = {10.1002/pssa.201431944}, pages = {1368 -- 1374}, year = {2015}, abstract = {Poly(N-isopropylacrylamide) (PNIPAAm) hydrogel films with incorporated graphene oxide (GO) were developed and tested as light-stimulated actuators. GO dispersions were synthesized via Hummers method and characterized toward their optical properties and photothermal energy conversion. The hydrogels were prepared by means of photopolymerization. In addition, the influence of GO within the hydrogel network on the lower critical solution temperature (LCST) was investigated by differential scanning calorimetry (DSC). The optical absorbance and the response to illumination were determined as a function of GO concentration for thin hydrogel films. A proof of principle for the stimulation with light was performed.}, language = {en} } @article{BreuerPilasGuthmannetal.2019, author = {Breuer, Lars and Pilas, Johanna and Guthmann, Eric and Sch{\"o}ning, Michael Josef and Thoelen, Ronald and Wagner, Torsten}, title = {Towards light-addressable flow control: responsive hydrogels with incorporated graphene oxide as laser-driven actuator structures within microfluidic channels}, series = {Sensor and Actuators B: Chemical}, volume = {288}, journal = {Sensor and Actuators B: Chemical}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0925-4005}, doi = {10.1016/j.snb.2019.02.086}, pages = {579 -- 585}, year = {2019}, language = {en} } @article{BreuerMangSchoeningetal.2017, author = {Breuer, Lars and Mang, Thomas and Sch{\"o}ning, Michael Josef and Thoelen, Ronald and Wagner, Torsten}, title = {Investigation of the spatial resolution of a laser-based stimulation process for light-addressable hydrogels with incorporated graphene oxide by means of IR thermography}, series = {Sensors and Actuators A: Physical}, volume = {268}, journal = {Sensors and Actuators A: Physical}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0924-4247}, doi = {10.1016/j.sna.2017.11.031}, pages = {126 -- 132}, year = {2017}, language = {en} } @article{BresselSchultzeKhanetal.2003, author = {Bressel, A. and Schultze, J.W. and Khan, W. and Wolfaardt, G. M. and Rohns, H.-P. and Irmscher, R. and Sch{\"o}ning, Michael Josef}, title = {High resolution gravimetric, optical and electrochemical investigations of microbial biofilm formation in aqueous systems}, series = {Electrochimica Acta. 48 (2003), H. 20-22}, journal = {Electrochimica Acta. 48 (2003), H. 20-22}, isbn = {0013-4686}, pages = {3363 -- 3372}, year = {2003}, language = {en} } @article{BreitschuhGraberHagemannetal.2003, author = {Breitschuh, S. and Graber, S. and Hagemann, Hans-J{\"u}rgen and Hemdt, A. vom and Schmitz, G{\"u}nter}, title = {Telematiklabore mit LabVIEW in der Ingenieurausbildung}, series = {Virtuelle Instrumente in der Praxis : Messtechnik, Automatisierung ; Begleitband zum Kongress VIP 2003 / Rahman Jamal ; Hans Jaschinski (Hrsg.).}, journal = {Virtuelle Instrumente in der Praxis : Messtechnik, Automatisierung ; Begleitband zum Kongress VIP 2003 / Rahman Jamal ; Hans Jaschinski (Hrsg.).}, publisher = {H{\"u}thig}, address = {Heidelberg [u.a.]}, isbn = {3-7785-2908-0}, pages = {458 -- 464}, year = {2003}, language = {de} } @article{BreitbachWolters1986, author = {Breitbach, Gerd and Wolters, J.}, title = {Der sowjetische Druckr{\"o}hren-Siedewasserreaktor / J. Wolters ; G. Breitbach}, series = {Atomwirtschaft - Atomtechnik. 31 (1986), H. 6}, journal = {Atomwirtschaft - Atomtechnik. 31 (1986), H. 6}, isbn = {0004-721x}, pages = {286 -- 289}, year = {1986}, language = {de} } @article{BreitbachWolfDeschkaetal.1992, author = {Breitbach, Gerd and Wolf, U. and Deschka, S. and Nickel, H.}, title = {Thermomechanical analysis of an actively cooled divertor mock up}, series = {Tagungsbericht : Jahrestagung Kerntechnik : Stadthalle Karlsruhe, 5.-7. Mai 1992, Karlsruhe = Proceedings / Kerntechnische Gesellschaft ... [Red.: Karl G. Bauer]. - 1. Aufl., als Ms. gedr..}, journal = {Tagungsbericht : Jahrestagung Kerntechnik : Stadthalle Karlsruhe, 5.-7. Mai 1992, Karlsruhe = Proceedings / Kerntechnische Gesellschaft ... [Red.: Karl G. Bauer]. - 1. Aufl., als Ms. gedr..}, publisher = {INFOFORUM}, address = {Bonn}, pages = {457 -- 461}, year = {1992}, language = {en} } @article{BreitbachSchubertAhmed1987, author = {Breitbach, Gerd and Schubert, F. and Ahmed, K.}, title = {Experimentelle und theoretische Untersuchungen zum Kriechbeulen von Rohren aus Ni Cr 22 Co 12 Mo bei 950 Cel / F. Schubert ; K. Ahmed ; G. Breitbach ...}, series = {Sicherheit und Verf{\"u}gbarkeit in der Anlagentechnik mit dem Schwerpunkt der Beitrag der Komponenten- und Grossprobenpr{\"u}fung zur Beurteilung von Bauteilen und Anlagen : [8. - 9. Oktober 1987] / Staatliche Materialpr{\"u}fungsanstalt Universit{\"a}t Stuttgart. - Bd. 2 : Rohrleitungsversagen, Komponenten, Thermoschock, Hochtemperaturverhalten, Beh{\"a}lterintegrit{\"a}t, Schweissverbindungen : (Vortr{\"a}ge 29 - 51)}, journal = {Sicherheit und Verf{\"u}gbarkeit in der Anlagentechnik mit dem Schwerpunkt der Beitrag der Komponenten- und Grossprobenpr{\"u}fung zur Beurteilung von Bauteilen und Anlagen : [8. - 9. Oktober 1987] / Staatliche Materialpr{\"u}fungsanstalt Universit{\"a}t Stuttgart. - Bd. 2 : Rohrleitungsversagen, Komponenten, Thermoschock, Hochtemperaturverhalten, Beh{\"a}lterintegrit{\"a}t, Schweissverbindungen : (Vortr{\"a}ge 29 - 51)}, publisher = {MPA}, address = {Stuttgart}, pages = {42.1 -- 42.18}, year = {1987}, language = {de} } @article{BreitbachSchubert2004, author = {Breitbach, Gerd and Schubert, F.}, title = {A contribution to stress prediction in coatings for gas turbine blades}, series = {Archive of applied mechanics. 73 (2004), H. 9-10}, journal = {Archive of applied mechanics. 73 (2004), H. 9-10}, isbn = {0939-1533}, pages = {682 -- 689}, year = {2004}, language = {en} } @article{BreitbachSchmidtPlutkaSchubertetal.1993, author = {Breitbach, Gerd and Schmidt-Plutka, A. and Schubert, F. and Nickel, H.}, title = {Deformation behaviour of structures exposed at very high temperatures to cyclic thermal and mechanical loadings}, series = {Structural mechanics in reactor technology : transactions of the 12th International Conference on Structural Mechanics in Reactor Technology, Stuttgart, Germany, 15-20 August 1993 / ed. Karl F. Kussmaul. - Bd. L : Inelastic behaviour of solids and structures}, journal = {Structural mechanics in reactor technology : transactions of the 12th International Conference on Structural Mechanics in Reactor Technology, Stuttgart, Germany, 15-20 August 1993 / ed. Karl F. Kussmaul. - Bd. L : Inelastic behaviour of solids and structures}, publisher = {Elsevier}, address = {Amsterdam [u.a.]}, isbn = {0-444-81515-5}, pages = {203 -- 208}, year = {1993}, language = {en} } @article{BreitbachSchmidtPlutkaSchubert1992, author = {Breitbach, Gerd and Schmidt-Plutka, A. and Schubert, F.}, title = {Untersuchungen zum Kriechratcheting bei dickwandigen Rohren / G. Breitbach ; A. Schmidt-Plutka ; F. Schubert ...}, series = {Sicherheit und Verf{\"u}gbarkeit in der Anlagentechnik mit dem Schwerpunkt Kerntechnik : vorrangige Thematik: Langzeitsicherheit und neue Reaktorkonzepte ; 8. und 9. Oktober 1992 / Staatliche Materialpr{\"u}fungsanstalt (MPA), Universit{\"a}t Stuttgart. - Bd. 1: Rohrleitungs- und Beh{\"a}lterintegrit{\"a}t, Bruchmechanik, Korrosion : (Vortr{\"a}ge 1 - 32)}, journal = {Sicherheit und Verf{\"u}gbarkeit in der Anlagentechnik mit dem Schwerpunkt Kerntechnik : vorrangige Thematik: Langzeitsicherheit und neue Reaktorkonzepte ; 8. und 9. Oktober 1992 / Staatliche Materialpr{\"u}fungsanstalt (MPA), Universit{\"a}t Stuttgart. - Bd. 1: Rohrleitungs- und Beh{\"a}lterintegrit{\"a}t, Bruchmechanik, Korrosion : (Vortr{\"a}ge 1 - 32)}, publisher = {MPA}, address = {Stuttgart}, pages = {9.1 -- 9.16}, year = {1992}, language = {de} } @article{BreitbachSchmidtPlutkaSchubert1992, author = {Breitbach, Gerd and Schmidt-Plutka, A. and Schubert, F.}, title = {Einfluß von Temperaturschwankungen auf das Verformungsverhalten von Rohren bei hohen Temperaturen}, series = {VGB-Konferenz "Restlebensdauer 1992" : 6. und 7. Juli 1992, Mannheim ; Vortr{\"a}ge = VGB Conference "Residual Service Life 1992" / VGB Technische Vereinigung der Grosskraftwerksbetreiber e.V. Leitung der Tagung: U. Gramberg. - Bd. 2}, journal = {VGB-Konferenz "Restlebensdauer 1992" : 6. und 7. Juli 1992, Mannheim ; Vortr{\"a}ge = VGB Conference "Residual Service Life 1992" / VGB Technische Vereinigung der Grosskraftwerksbetreiber e.V. Leitung der Tagung: U. Gramberg. - Bd. 2}, address = {Mannheim}, pages = {1 -- 16}, year = {1992}, language = {de} } @article{BreitbachPenkallaSchubert1989, author = {Breitbach, Gerd and Penkalla, H.-J. and Schubert, F.}, title = {Diskussion eines neuen ORNL-Stoffgesetzes fuer Inconel 617 / H.-J. Penkalla ; G. Breitbach ; F. Schubert}, series = {Sicherheit und Verf{\"u}gbarkeit in der Anlagentechnik mit dem Schwerpunkt Langzeitintegrit{\"a}t der druckf{\"u}hrenden Bauteile von Kernkraftwerken : [5. - 6. Oktober 1989] / Staatliche Materialpr{\"u}fungsanstalt Universit{\"a}t Stuttgart. - Bd. 2 : Zeitstandvehalten, Kriechvorg{\"a}nge, Rohrleitungsverhalten, Bruchmechanik : (Vortr{\"a}ge 23 - 45)}, journal = {Sicherheit und Verf{\"u}gbarkeit in der Anlagentechnik mit dem Schwerpunkt Langzeitintegrit{\"a}t der druckf{\"u}hrenden Bauteile von Kernkraftwerken : [5. - 6. Oktober 1989] / Staatliche Materialpr{\"u}fungsanstalt Universit{\"a}t Stuttgart. - Bd. 2 : Zeitstandvehalten, Kriechvorg{\"a}nge, Rohrleitungsverhalten, Bruchmechanik : (Vortr{\"a}ge 23 - 45)}, publisher = {MPA}, address = {Stuttgart}, pages = {28.1 -- 28.20}, year = {1989}, language = {de} } @article{BreitbachOverBieniussa1984, author = {Breitbach, Gerd and Over, H. H. and Bieniussa, K.}, title = {Einfluss von thermisch induzierten Sekund{\"a}rspannungen auf die Lebensdauer eines im Hochtemperaturbereich beanspruchten Bauteils / H. H. Over ; G. Breitbach ; K. Bieniussa}, series = {Sicherheit und Verf{\"u}gbarkeit in der Anlagentechnik mit dem Schwerpunkt Bruchausschluss : [10. - 13. Oktober 1984] / Staatliche Materialpr{\"u}fungsanstalt, Universit{\"a}t Stuttgart. - Bd. 2 : Bruchausschluß, Thermoschock, Hochtemperaturreaktor/SNR, Anlagentechnik : (Vortr{\"a}ge 28 - 50)}, journal = {Sicherheit und Verf{\"u}gbarkeit in der Anlagentechnik mit dem Schwerpunkt Bruchausschluss : [10. - 13. Oktober 1984] / Staatliche Materialpr{\"u}fungsanstalt, Universit{\"a}t Stuttgart. - Bd. 2 : Bruchausschluß, Thermoschock, Hochtemperaturreaktor/SNR, Anlagentechnik : (Vortr{\"a}ge 28 - 50)}, publisher = {MPA}, address = {Stuttgart}, pages = {43.1 -- 43.11}, year = {1984}, language = {de} } @article{BreitbachNickelSchubert1990, author = {Breitbach, Gerd and Nickel, H. and Schubert, F.}, title = {Stand der Aktivit{\"a}ten zu Regelwerken f{\"u}r heliumgek{\"u}hlte Hochtemperaturreaktoren / H. Nickel ; F. Schubert ; G. Breitbach}, series = {Atomwirtschaft - Atomtechnik. 35 (1990), H. 2}, journal = {Atomwirtschaft - Atomtechnik. 35 (1990), H. 2}, isbn = {0004-721x}, pages = {74 -- 79}, year = {1990}, language = {de} } @article{BreitbachMohrKroeger1983, author = {Breitbach, Gerd and Mohr, H.-G. and Kroeger, W.}, title = {Kann der Aufwand f{\"u}r qualit{\"a}tssichernde Maßnahmen bei 'kleinen Reaktoren' gering gehalten werden? / H.-G. Mohr ; W. Kroeger ; G. Breitbach}, series = {Kerntechnik '83 : Jahrestagung Kerntechnik , Berlin, 14.-16. Juni 1983. Tagungsbericht / Hrsg.: Kerntechnische Gesellschaft e.V. und Deutsches Atomforum e.V.}, journal = {Kerntechnik '83 : Jahrestagung Kerntechnik , Berlin, 14.-16. Juni 1983. Tagungsbericht / Hrsg.: Kerntechnische Gesellschaft e.V. und Deutsches Atomforum e.V.}, publisher = {Deutsches Atomforum}, address = {Bonn}, isbn = {0173-0924}, pages = {199 -- 202}, year = {1983}, language = {de} } @article{BreitbachKlomfassHannen1992, author = {Breitbach, Gerd and Klomfass, J. and Hannen, W.}, title = {Temperatur- und Dehnungsmessung an komplex beanspruchten metallischen Bauteilen im Temperaturbereich um 900 C / J. Klomfass ; W. Hannen ; G. Breitbach}, series = {Vortr{\"a}ge der Tagung Werkstoffpr{\"u}fung 1992 : 3. und 4. Dezember 1992 in Bad Nauheim / DVM, Deutscher Verband f{\"u}r Materialforschung und -pr{\"u}fung e.V. Veranstaltet von: Deutsche Gesellschaft f{\"u}r Materialkunde ...}, journal = {Vortr{\"a}ge der Tagung Werkstoffpr{\"u}fung 1992 : 3. und 4. Dezember 1992 in Bad Nauheim / DVM, Deutscher Verband f{\"u}r Materialforschung und -pr{\"u}fung e.V. Veranstaltet von: Deutsche Gesellschaft f{\"u}r Materialkunde ...}, publisher = {DVM}, address = {Berlin}, pages = {93 -- 100}, year = {1992}, language = {de} } @article{BreitbachJahnRehm1985, author = {Breitbach, Gerd and Jahn, W. and Rehm, W.}, title = {Prim{\"a}rkreislauf - Thermodynamik und Komponentenbelastung}, series = {Sicherheitstechnische Untersuchungen zum St{\"o}rfallverhalten des HTR-Modul / [KFA, Kernforschungsanlage J{\"u}lich, GmbH, Inst. f{\"u}r Nukleare Sicherheitsforschung] / zsgest. von J. Mertens}, journal = {Sicherheitstechnische Untersuchungen zum St{\"o}rfallverhalten des HTR-Modul / [KFA, Kernforschungsanlage J{\"u}lich, GmbH, Inst. f{\"u}r Nukleare Sicherheitsforschung] / zsgest. von J. Mertens}, publisher = {Zentralbibliothek der Kernforschungsanlage}, address = {J{\"u}lich}, pages = {61 -- 98}, year = {1985}, language = {de} } @article{BreitbachDeschkaAkiba1992, author = {Breitbach, Gerd and Deschka, S. and Akiba, M.}, title = {High heat flux tests on brazed divertor components in electron and ion beam test facilities / S. Deschka ; M. Akiba ; G. Breitbach ...}, series = {International journal of refractory metals and hard materials. 11 (1992), H. 6}, journal = {International journal of refractory metals and hard materials. 11 (1992), H. 6}, isbn = {0263-4368}, pages = {367 -- 375}, year = {1992}, language = {en} } @article{BreitbachDavidLohnert1984, author = {Breitbach, Gerd and David, P.-H. and Lohnert, G.-H.}, title = {Absch{\"a}tzung des langfristigen Lufteintrags nach einem Druckentlastungsst{\"o}rfall des HTR-Modul}, series = {Jahrestagung Kerntechnik '84 : Alte Oper, Frankfurt, 22. - 24. Mai 1984 ; Tagungsbericht / Kerntechnische Gesellschaft}, journal = {Jahrestagung Kerntechnik '84 : Alte Oper, Frankfurt, 22. - 24. Mai 1984 ; Tagungsbericht / Kerntechnische Gesellschaft}, publisher = {Deutsches Atomforum}, address = {Bonn}, isbn = {0173-0924}, pages = {287 -- 290}, year = {1984}, language = {de} } @article{BreitbachAltesSzimmat1989, author = {Breitbach, Gerd and Altes, J. and Szimmat, J.}, title = {Anwendung der Finite-Element-Methode bei der Berechnung des W{\"a}rmetransports durch Strahlung / J. Altes ; G. Breitbach ; J. Szimmat}, series = {International FEM-Congress : Baden-Baden, Federal Republic of Germany, 17./18. November 1986}, journal = {International FEM-Congress : Baden-Baden, Federal Republic of Germany, 17./18. November 1986}, publisher = {IKO Software Service GmbH}, address = {Stuttgart}, pages = {127 -- 148}, year = {1989}, language = {de} } @article{Breitbach1983, author = {Breitbach, Gerd}, title = {Spannungs- und Kriechsch{\"a}digungsanalyse f{\"u}r die Rohre eines HTR-beheizten R{\"o}hrenspaltofens}, series = {Kerntechnik '83 : Jahrestagung Kerntechnik , Berlin, 14.-16. Juni 1983. Tagungsbericht / Hrsg.: Kerntechnische Gesellschaft e.V. und Deutsches Atomforum e.V.}, journal = {Kerntechnik '83 : Jahrestagung Kerntechnik , Berlin, 14.-16. Juni 1983. Tagungsbericht / Hrsg.: Kerntechnische Gesellschaft e.V. und Deutsches Atomforum e.V.}, publisher = {Deutsches Atomforum}, address = {Bonn}, isbn = {0173-0924}, pages = {659 -- 662}, year = {1983}, language = {de} } @article{BraunChengDoweyetal.2021, author = {Braun, Sebastian and Cheng, Chi-Tsun and Dowey, Steve and Wollert, J{\"o}rg}, title = {Performance evaluation of skill-based order-assignment in production environments with multi-agent systems}, series = {IEEE Journal of Emerging and Selected Topics in Industrial Electronics}, journal = {IEEE Journal of Emerging and Selected Topics in Industrial Electronics}, number = {Early Access}, publisher = {IEEE}, address = {New York}, issn = {2687-9735}, doi = {10.1109/JESTIE.2021.3108524}, year = {2021}, abstract = {The fourth industrial revolution introduces disruptive technologies to production environments. One of these technologies are multi-agent systems (MASs), where agents virtualize machines. However, the agent's actual performances in production environments can hardly be estimated as most research has been focusing on isolated projects and specific scenarios. We address this gap by implementing a highly connected and configurable reference model with quantifiable key performance indicators (KPIs) for production scheduling and routing in single-piece workflows. Furthermore, we propose an algorithm to optimize the search of extrema in highly connected distributed systems. The benefits, limits, and drawbacks of MASs and their performances are evaluated extensively by event-based simulations against the introduced model, which acts as a benchmark. Even though the performance of the proposed MAS is, on average, slightly lower than the reference system, the increased flexibility allows it to find new solutions and deliver improved factory-planning outcomes. Our MAS shows an emerging behavior by using flexible production techniques to correct errors and compensate for bottlenecks. This increased flexibility offers substantial improvement potential. The general model in this paper allows the transfer of the results to estimate real systems or other models.}, language = {en} } @article{BrahmaMusioIsmayilovaetal.2015, author = {Brahma, Aischarya and Musio, Biagia and Ismayilova, Uliviya and Nikbin, Nikzad and Kamptmann, Sonja B. and Siegert, Petra and Jeromin, G{\"u}nter Erich and Ley, Steven and Pohl, Martina}, title = {An orthogonal biocatalytic approach for the safe generation and use of HCN in a multi-step continuous preparation of chiral O-acetylcyanohydrins}, series = {Synlett}, journal = {Synlett}, number = {Publ. online 29.09.2015}, publisher = {Thieme}, address = {Stuttgart}, issn = {0936-5214 (Print) ; 1437-2096 (e-Journal)}, doi = {10.1055/s-0035-1560644}, year = {2015}, language = {de} } @article{BragardvanHoekDeDoncker2012, author = {Bragard, Michael and van Hoek, H. and De Doncker, R. W.}, title = {A major design step in IETO concept realization that allows overcurrent protection and pushes limits of switching performance}, series = {IEEE transactions on power electronics}, volume = {27}, journal = {IEEE transactions on power electronics}, number = {9}, publisher = {IEEE}, address = {New York}, issn = {0885-8993}, doi = {10.1109/TPEL.2012.2189136}, pages = {4163 -- 4171}, year = {2012}, abstract = {This paper presents the latest prototype of the integrated emitter turn-off thyristor concept, which potentially ranks among thyristor high-power devices like the gate turn-off thyristor and the integrated gate-commutated thyristor (IGCT). Due to modifications of the external driver stage and mechanical press-pack design optimization, this prototype allows for full device characterization. The turn-off capability was increased to 1600 A with an active silicon area of 823mm2 . This leads to a transient peak power of 672.1kW/cm² . Within this paper, measurements and concept assessment are presented and a comparison to state-of-the-art IGCT devices is provided.}, language = {en} } @article{BragardSoltauThomasetal.2010, author = {Bragard, Michael and Soltau, N. and Thomas, S. and De Doncker, R. W.}, title = {The balance of renewable sources and user demands in grids : power electronics for modular battery energy storage systems}, series = {IEEE transactions on power electronics}, volume = {25}, journal = {IEEE transactions on power electronics}, number = {12}, publisher = {IEEE}, address = {New York}, issn = {0885-8993}, doi = {10.1109/TPEL.2010.2085455}, pages = {3049 -- 3056}, year = {2010}, abstract = {The continuously growing amount of renewable sources starts compromising the stability of electrical grids. Contradictory to fossil fuel power plants, energy production of wind and photovoltaic (PV) energy is fluctuating. Although predictions have significantly improved, an outage of multi-MW offshore wind farms poses a challenging problem. One solution could be the integration of storage systems in the grid. After a short overview, this paper focuses on two exemplary battery storage systems, including the required power electronics. The grid integration, as well as the optimal usage of volatile energy reserves, is presented for a 5- kW PV system for home application, as well as for a 100- MW medium-voltage system, intended for wind farm usage. The efficiency and cost of topologies are investigated as a key parameter for large-scale integration of renewable power at medium- and low-voltage.}, language = {en} } @article{BragardRichter2008, author = {Bragard, Michael and Richter, S. A.}, title = {LED-Kreisel als Praxis-Booster}, series = {Elektor : electronics worldwide}, volume = {39}, journal = {Elektor : electronics worldwide}, number = {12}, issn = {0932-5468}, pages = {16}, year = {2008}, language = {de} } @article{BragardConradvanHoeketal.2011, author = {Bragard, Michael and Conrad, M. and van Hoek, H. and De Doncker, R. W.}, title = {The integrated emitter turn-off thyristor (IETO) : an innovative thyristor-based high power semiconductor device using MOS assisted turn-off}, series = {IEEE transactions on industry applications}, volume = {47}, journal = {IEEE transactions on industry applications}, number = {5}, publisher = {IEEE}, address = {New York}, issn = {0093-9994}, doi = {10.1109/TIA.2011.2161432}, pages = {2175 -- 2182}, year = {2011}, language = {en} } @article{BragardBragard2003, author = {Bragard, Michael and Bragard, G.}, title = {Erweiterungen f{\"u}r das CBL2-Messinterface von Texas-Instruments}, series = {Der mathematische und naturwissenschaftliche Unterricht : MNU ; Organ des Deutschen Vereins zur F{\"o}rderung des Mathematischen und Naturwissenschaftlichen Unterrichts e.V.}, volume = {56}, journal = {Der mathematische und naturwissenschaftliche Unterricht : MNU ; Organ des Deutschen Vereins zur F{\"o}rderung des Mathematischen und Naturwissenschaftlichen Unterrichts e.V.}, number = {2}, publisher = {Seeberger}, address = {Neuss}, issn = {0025-5866}, pages = {87 -- 88}, year = {2003}, abstract = {Das von Texas-Instruments (TI) vertriebene Interface CBL2 wird {\"u}ber einige TI-Grafik-Rechner (TI-92, TI-89 usw.) angesteuert. Wegen seiner Handlichkeit wird dieses System beim Unterricht in wechselnden R{\"a}umen »großen« Messwerterfassungssystemen oft vorgezogen. Das CBL2 bietet drei analoge Eing{\"a}nge, die immerhin mit 10 Bit Aufl{\"o}sung und bis zu einer Frequenz von 50 kHz arbeiten. Weiterhin besitzt das CBL2 eine Buchse f{\"u}r angeblich nur einen digitalen Ein- bzw. Ausgang. An diesem Eingang wird standardm{\"a}ßig haupts{\"a}chlich der Bewegungssensor CBR betrieben. In diesem Beitrag werden Erweiterungsm{\"o}glichkeiten dieses Anschlusses beschrieben.}, language = {de} } @article{Bragard2008, author = {Bragard, Michael}, title = {Effektvoller LED-Kreisel : zeigt Text wie programmiert, wenn er rotiert}, series = {Elektor : electronics worldwide}, volume = {39}, journal = {Elektor : electronics worldwide}, number = {12}, issn = {0932-5468}, pages = {18 -- 23}, year = {2008}, abstract = {Wenn eine runde Platine mit LED-Zeile rotiert, entstehen leuchtende Ringe. Steuert man die LEDs mit einem Mikrocontroller an, lassen sich aber auch "stehende" Bilder darstellen. Unser elektronischer Kreisel kann Buchstaben und Ziffern anzeigen. Dabei wird das Erdmagnetfeld auf clevere Weise zur Synchronisation genutzt. Hier reichen die Anwendungen vom Rundenz{\"a}hler bis zum Kompass!}, language = {de} } @article{BragardBragard2012, author = {Bragard, G. and Bragard, Michael}, title = {Ein kosteng{\"u}nstiges, universelles Modellbauinterface}, series = {Der mathematische und naturwissenschaftliche Unterricht : MNU ; Organ des Deutschen Vereins zur F{\"o}rderung des Mathematischen und Naturwissenschaftlichen Unterrichts e.V.}, volume = {65}, journal = {Der mathematische und naturwissenschaftliche Unterricht : MNU ; Organ des Deutschen Vereins zur F{\"o}rderung des Mathematischen und Naturwissenschaftlichen Unterrichts e.V.}, number = {5}, publisher = {Seeberger}, address = {Neuss}, issn = {0025-5866}, pages = {290 -- 293}, year = {2012}, abstract = {Wir stellen einen USB-Baustein vor, der eine kosteng{\"u}nstige und universelle M{\"o}glichkeit schafft , im Unterricht den Themenkreis Messen-Steuern-Regeln zu behandeln. Die Funktionalit{\"a}t orientiert sich am CVK-Interface der Firma Fischertechnik. Im Gegensatz zu kommerziellen L{\"o}sungen erlaubt unser Aufbau auch den preiswerten Einsatz in Gruppen- oder Einzelarbeit. Abschließend berichten wir {\"u}ber ein Beispiel aus dem Unterrichtseinsatz.}, language = {de} } @article{BrabandYegenPaulssenetal.2005, author = {Braband, Henrik and Yegen, Eda and Paulßen, Elisabeth and Abram, Ulrich}, title = {[{ReN(PMe2Ph)3}{ReO3N}]2 - Structural Evidence for the Nitridotrioxorhenate(VII) Anion, [ReO3N]2-}, series = {Zeitschrift f{\"u}r anorganische und allgemeine Chemie : ZAAC = Journal of inorganic and general chemistry}, volume = {631}, journal = {Zeitschrift f{\"u}r anorganische und allgemeine Chemie : ZAAC = Journal of inorganic and general chemistry}, number = {12}, issn = {1521-3749}, doi = {10.1002/zaac.200500240}, pages = {2408 -- 2410}, year = {2005}, language = {en} } @article{BrabandPaulssenAbram2006, author = {Braband, Henrik and Paulßen, Elisabeth and Abram, Ulrich}, title = {Nitridorhenium(V) Complexes with 1,3-Dialkyl-4,5-dimethylimidazole-2-ylidenes}, series = {Zeitschrift f{\"u}r anorganische und allgemeine Chemie : ZAAC = Journal of inorganic and general chemistry}, volume = {632}, journal = {Zeitschrift f{\"u}r anorganische und allgemeine Chemie : ZAAC = Journal of inorganic and general chemistry}, number = {6}, issn = {1521-3749}, doi = {10.1002/zaac.200600002}, pages = {1051 -- 1056}, year = {2006}, language = {en} } @article{BouwmanGuldenHeijdenetal.2013, author = {Bouwman, Peter and Gulden, Hanneke van der and Heijden, Ingrid van der and Drost, Rinske and Klijn, Christiaan N. and Prasetyanti, Pramudita and Pieterse, Mark and Wientjens, Ellen and Seibler, Jost and Hogervorst, Frank B. L. and Jonkers, Jos}, title = {A High-Throughput Functional Complementation Assay for Classification of BRCA1 Missense Variants}, series = {Cancer Discovery}, journal = {Cancer Discovery}, number = {3}, issn = {2159-8290}, doi = {10.1158/2159-8290.CD-13-0094}, pages = {1142 -- 1152}, year = {2013}, language = {en} } @article{BouquegneauKernRousseau2010, author = {Bouquegneau, Christian and Kern, Alexander and Rousseau, Alain}, title = {Lightning safety guidelines}, pages = {1 -- 6}, year = {2010}, language = {en} } @article{BornheimGriegerBlanecketal.2024, author = {Bornheim, Tobias and Grieger, Niklas and Blaneck, Patrick Gustav and Bialonski, Stephan}, title = {Speaker Attribution in German Parliamentary Debates with QLoRA-adapted Large Language Models}, series = {Journal for language technology and computational linguistics : JLCL}, volume = {37}, journal = {Journal for language technology and computational linguistics : JLCL}, number = {1}, publisher = {Gesellschaft f{\"u}r Sprachtechnologie und Computerlinguistik}, address = {Regensburg}, issn = {2190-6858}, doi = {10.21248/jlcl.37.2024.244}, pages = {13 Seiten}, year = {2024}, abstract = {The growing body of political texts opens up new opportunities for rich insights into political dynamics and ideologies but also increases the workload for manual analysis. Automated speaker attribution, which detects who said what to whom in a speech event and is closely related to semantic role labeling, is an important processing step for computational text analysis. We study the potential of the large language model family Llama 2 to automate speaker attribution in German parliamentary debates from 2017-2021. We fine-tune Llama 2 with QLoRA, an efficient training strategy, and observe our approach to achieve competitive performance in the GermEval 2023 Shared Task On Speaker Attribution in German News Articles and Parliamentary Debates. Our results shed light on the capabilities of large language models in automating speaker attribution, revealing a promising avenue for computational analysis of political discourse and the development of semantic role labeling systems.}, language = {en} } @article{BorkKelemenBisellietal.2000, author = {Bork, M. and Kelemen, C. and Biselli, Manfred and Artmann, Gerhard}, title = {Biophysikalische Charakterisierung ex vivo kultivierter menschlicher Erythrozythen}, series = {Biomedizinische Technik = Biomedical Engineering. 45 (2000), H. s1}, journal = {Biomedizinische Technik = Biomedical Engineering. 45 (2000), H. s1}, isbn = {1862-278X}, pages = {471 -- 472}, year = {2000}, language = {de} } @article{BorgmeierBongaertsMeinhardt2012, author = {Borgmeier, Claudia and Bongaerts, Johannes and Meinhardt, Friedhelm}, title = {Genetic analysis of the Bacillus licheniformis degSU operon and the impact of regulatory mutations on protease production}, series = {Journal of biotechnology}, volume = {159}, journal = {Journal of biotechnology}, number = {1-2}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1873-4863 (E-Journal); 0168-1656 (Print)}, doi = {10.1016/j.jbiotec.2012.02.011}, pages = {12 -- 20}, year = {2012}, abstract = {Disruption experiments targeted at the Bacillus licheniformis degSU operon and GFP-reporter analysis provided evidence for promoter activity immediately upstream of degU. pMutin mediated concomitant introduction of the degU32 allele - known to cause hypersecretion in Bacillus subtilis - resulted in a marked increase in protease activity. Application of 5-fluorouracil based counterselection through establishment of a phosphoribosyltransferase deficient Δupp strain eventually facilitated the marker-free introduction of degU32 leading to further protease enhancement achieving levels as for hypersecreting wild strains in which degU was overexpressed. Surprisingly, deletion of rapG - known to interfere with DegU DNA-binding in B. subtilis - did not enhance protease production neither in the wild type nor in the degU32 strain. The combination of degU32 and Δupp counterselection in the type strain is not only equally effective as in hypersecreting wild strains with respect to protease production but furthermore facilitates genetic strain improvement aiming at biological containment and effectiveness of biotechnological processes.}, language = {en} } @article{BorchertSchemm2007, author = {Borchert, J{\"o}rg and Schemm, R.}, title = {Einsatz der Portfoliotheorie im Asset Allokations-Prozess am Beispiel eines fiktiven Anlageraumes von Windkraftstandorten}, series = {Zeitschrift f{\"u}r Energiewirtschaft}, volume = {31}, journal = {Zeitschrift f{\"u}r Energiewirtschaft}, number = {4}, issn = {0343-5377}, pages = {311}, year = {2007}, language = {de} } @article{BorchertHasenbeckJungbluthetal.2009, author = {Borchert, J{\"o}rg and Hasenbeck, Marc and Jungbluth, Christian and Schemm, Ralf}, title = {Bewertung und Steuerung von Gasspeichern bzw. Gasspeicherscheiben}, series = {Zeitschrift f{\"u}r Energiewirtschaft}, volume = {33}, journal = {Zeitschrift f{\"u}r Energiewirtschaft}, number = {4}, publisher = {Springer}, address = {Berlin}, issn = {1866-2765}, doi = {10.1007/s12398-009-0033-x}, pages = {279 -- 293}, year = {2009}, abstract = {In diesem Artikel werden zun{\"a}chst einleitend der Gasmarkt Deutschland und der sich daraus ergebende Speicherbedarf skizziert. Folgend wird auf verschiedene Speichernutzen aus betriebswirtschaftlicher Perspektive eingegangen und die in diesem Artikel vorgestellten Bewertungsverfahren einleitend beschrieben. In diesem Artikel werden stochastische Optimierungsmethoden aufgegriffen, die sowohl eine Bewertung der Speicher gegen{\"u}ber einem Spotpreis, als auch gegen{\"u}ber einer gesamten Forwardcurve erm{\"o}glichen. Hierzu werden zun{\"a}chst Modelle zur Beschreibung der Marktpreise vorgestellt und anhand empirischer Daten kalibriert. Dann wird eine beispielhafte Speicherscheibe zun{\"a}chst auf Basis der LeastSquareMonteCarloTechnik gegen{\"u}ber dem stochastischen mehrfaktoriellen Spotpreismodell bewertet. Hieran schließt sich die Vorstellung der Bewertung sowie des Hedgings gegen{\"u}ber der Forwardcurve an. Abschließend erfolgt eine vergleichende Gegen{\"u}berstellung beider Verfahren.}, language = {de} } @article{BorchertHasenbeck2009, author = {Borchert, J{\"o}rg and Hasenbeck, Marc}, title = {Bewertung und Steuerung von Kraftwerksscheiben}, series = {Zeitschrift f{\"u}r Energiewirtschaft}, volume = {33}, journal = {Zeitschrift f{\"u}r Energiewirtschaft}, number = {2}, publisher = {Vieweg}, address = {Wiesbaden}, issn = {1866-2765}, doi = {10.1007/s12398-009-0014-0}, pages = {115 -- 126}, year = {2009}, language = {de} } @article{Borchert2003, author = {Borchert, J{\"o}rg}, title = {Von Beschaffern und Spekulanten}, series = {Energie \& Management}, journal = {Energie \& Management}, number = {3}, issn = {0945-8794}, pages = {16 -- 17}, year = {2003}, language = {de} } @article{BooysenRiegerFerrein2011, author = {Booysen, Tracy and Rieger, Michael and Ferrein, Alexander}, title = {Towards inexpensive robots for science \& technology teaching and education in Africa}, publisher = {IEEE}, address = {New York}, isbn = {978-1-61284-992-8}, pages = {1 -- 6}, year = {2011}, language = {en} } @article{BongaertsZoschkeWeidneretal.1995, author = {Bongaerts, Johannes and Zoschke, Sascha and Weidner, Uwe and Linden, Gottfried}, title = {Transcriptional regulation of the proton translocating NADH}, series = {Molecular microbiology}, volume = {Vol. 16}, journal = {Molecular microbiology}, number = {Iss. 3}, issn = {1365-2958 (E-Journal); 0950-382x (Print)}, pages = {521 -- 534}, year = {1995}, language = {en} }