@article{RoehlenPilasSchoeningetal.2017, author = {R{\"o}hlen, Desiree and Pilas, Johanna and Sch{\"o}ning, Michael Josef and Selmer, Thorsten}, title = {Development of an amperometric biosensor platform for the combined determination of l-Malic, Fumaric, and l-Aspartic acid}, series = {Applied Biochemistry and Biotechnology}, volume = {183}, journal = {Applied Biochemistry and Biotechnology}, publisher = {Springer}, address = {Berlin}, issn = {1559-0291}, doi = {10.1007/s12010-017-2578-1}, pages = {566 -- 581}, year = {2017}, abstract = {Three amperometric biosensors have been developed for the detection of L-malic acid, fumaric acid, and L -aspartic acid, all based on the combination of a malate-specific dehydrogenase (MDH, EC 1.1.1.37) and diaphorase (DIA, EC 1.8.1.4). The stepwise expansion of the malate platform with the enzymes fumarate hydratase (FH, EC 4.2.1.2) and aspartate ammonia-lyase (ASPA, EC 4.3.1.1) resulted in multi-enzyme reaction cascades and, thus, augmentation of the substrate spectrum of the sensors. Electrochemical measurements were carried out in presence of the cofactor β-nicotinamide adenine dinucleotide (NAD+) and the redox mediator hexacyanoferrate (III) (HCFIII). The amperometric detection is mediated by oxidation of hexacyanoferrate (II) (HCFII) at an applied potential of + 0.3 V vs. Ag/AgCl. For each biosensor, optimum working conditions were defined by adjustment of cofactor concentrations, buffer pH, and immobilization procedure. Under these improved conditions, amperometric responses were linear up to 3.0 mM for L-malate and fumarate, respectively, with a corresponding sensitivity of 0.7 μA mM-1 (L-malate biosensor) and 0.4 μA mM-1 (fumarate biosensor). The L-aspartate detection system displayed a linear range of 1.0-10.0 mM with a sensitivity of 0.09 μA mM-1. The sensor characteristics suggest that the developed platform provides a promising method for the detection and differentiation of the three substrates.}, language = {en} } @article{BiselliVanderPolJokschetal.1992, author = {Biselli, Manfred and Van der Pol, Jens J. and Joksch, B. and Eberhardt, R.}, title = {Development of an enzymatic multichannel flow injection analysis system for monitoring mammalian cell fermentations / Van der Pol, J.J.; Joksch, B.; Eberhardt, R.; Biselli, M.; Wandrey, C., Tramper, J.}, series = {Biosensors : fundamentals, technologies and applications ; contributions to the BMFT status seminar with international participation May, 12 to 14, 1991, Internationales Bildungs-Centrum Bogensee/Brandenburg, Germany / org. by ZIM-Zentralinstitut f{\"u}r Molekularbiologie, Berlin-Buch and GBF, Braunschweig. Ed. by F. Scheller}, journal = {Biosensors : fundamentals, technologies and applications ; contributions to the BMFT status seminar with international participation May, 12 to 14, 1991, Internationales Bildungs-Centrum Bogensee/Brandenburg, Germany / org. by ZIM-Zentralinstitut f{\"u}r Molekularbiologie, Berlin-Buch and GBF, Braunschweig. Ed. by F. Scheller}, publisher = {VCH}, address = {Weinheim}, isbn = {3527284370}, pages = {349 -- 352}, year = {1992}, language = {en} } @article{BaumannJahnke1986, author = {Baumann, Marcus and Jahnke, J.}, title = {Die marine Planktonalge Phaeocystis globosa / Jahnke, J. ; Baumann, M.}, series = {Mikrokosmos. 75 (1986), H. 12}, journal = {Mikrokosmos. 75 (1986), H. 12}, isbn = {0026-3680}, pages = {357 -- 359}, year = {1986}, language = {de} } @article{KowollikSchnitzlerBisellietal.2010, author = {Kowollik, S. and Schnitzler, Thomas and Biselli, Manfred and Krueger, R. and Zang, Werner and Peuscher, A. and Schillberg, S. and Fischer, R.}, title = {Die Rolle des Respirationsquotienten in der Zellkulturfermentation}, series = {Chemie Ingenieur Technik}, volume = {82}, journal = {Chemie Ingenieur Technik}, number = {9}, isbn = {Chemie Ingenieur Tec}, pages = {1505 -- 1506}, year = {2010}, language = {de} } @article{BiselliNoll1998, author = {Biselli, Manfred and Noll, T.}, title = {Dielectric spectroscopy in the cultivation of suspended and immobilized hybridoma cells / Noll, T.; Biselli, M.}, series = {Journal of Biotechnology. 63 (1998), H. 3}, journal = {Journal of Biotechnology. 63 (1998), H. 3}, isbn = {0168-1656}, pages = {187 -- 198}, year = {1998}, language = {en} } @article{CapitainRossJonesMoehringetal.2020, author = {Capitain, Charlotte and Ross-Jones, Jesse and M{\"o}hring, Sophie and Tippk{\"o}tter, Nils}, title = {Differential scanning calorimetry for quantification of polymer biodegradability in compost}, series = {International Biodeterioration \& Biodegradation}, volume = {149}, journal = {International Biodeterioration \& Biodegradation}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0964-8305}, doi = {10.1016/j.ibiod.2020.104914}, pages = {In Press, Article number 104914}, year = {2020}, abstract = {The objective of this study is the establishment of a differential scanning calorimetry (DSC) based method for online analysis of the biodegradation of polymers in complex environments. Structural changes during biodegradation, such as an increase in brittleness or crystallinity, can be detected by carefully observing characteristic changes in DSC profiles. Until now, DSC profiles have not been used to draw quantitative conclusions about biodegradation. A new method is presented for quantifying the biodegradation using DSC data, whereby the results were validated using two reference methods. The proposed method is applied to evaluate the biodegradation of three polymeric biomaterials: polyhydroxybutyrate (PHB), cellulose acetate (CA) and Organosolv lignin. The method is suitable for the precise quantification of the biodegradability of PHB. For CA and lignin, conclusions regarding their biodegradation can be drawn with lower resolutions. The proposed method is also able to quantify the biodegradation of blends or composite materials, which differentiates it from commonly used degradation detection methods.}, language = {en} } @article{JahnkeBaumann1987, author = {Jahnke, J. and Baumann, Marcus}, title = {Differentiation between Phaeocystis pouchetii (Har.) Lagerheim and Phaeocystis globosa Scherffel}, series = {Hydrobiological bulletin}, volume = {Vol. 21}, journal = {Hydrobiological bulletin}, number = {Iss. 2}, issn = {0165-1404 (Print); 1573-5125 (E-Journal)}, pages = {141 -- 147}, year = {1987}, language = {en} } @article{BiselliSchroederHerfurthetal.1997, author = {Biselli, Manfred and Schr{\"o}der, B. and Herfurth, C. and Meißner, P.}, title = {Differentiation of bone marrow cells immobilized on microcarriers in a fluidized bed reactor / Schr{\"o}der, B. ; Herfurth, C. ; Meißner, P. ; Biselli, M. ; Link, H. ; Wandrey, C.}, series = {Animal cell technology : from vaccines to genetic medicine ; [Vilamoura, Portugal, May 1996] / ed. by Manuel J. T. Carrondo}, journal = {Animal cell technology : from vaccines to genetic medicine ; [Vilamoura, Portugal, May 1996] / ed. by Manuel J. T. Carrondo}, publisher = {Kluwer}, address = {Dordrecht}, isbn = {0-7923-4321-2}, pages = {589 -- 593}, year = {1997}, language = {en} } @article{KotterHeeringRiekert1982, author = {Kotter, Michael and Heering, J. and Riekert, L.}, title = {Diffusion and catalytic reaction in zeolite ZSM-5 / J. Heering ; M. Kotter ; L. Riekert}, series = {Chemical engineering science . 37 (1982), H. 4}, journal = {Chemical engineering science . 37 (1982), H. 4}, isbn = {0009-2509}, pages = {581 -- 584}, year = {1982}, language = {en} } @article{PrielmeierSpeedyVardagetal.1989, author = {Prielmeier, Franz and Speedy, R. J. and Vardag, T. and Lang, E. W.}, title = {Diffusion in simple fluids / R. J. Speedy; F. X. Prielmeier; T. Vardag; E. W. Lang; H.-D. L{\"u}demann}, series = {Molecular Physics. 66 (1989), H. 3}, journal = {Molecular Physics. 66 (1989), H. 3}, isbn = {0026-8976}, pages = {577 -- 590}, year = {1989}, language = {en} } @article{PrielmeierLangSpeedyetal.1987, author = {Prielmeier, Franz and Lang, E. W. and Speedy, R. J. and L{\"u}demann, H.-D.}, title = {Diffusion in supercooled water to 300 MPa}, series = {Physical Review Letters. 59 (1987), H. 10}, journal = {Physical Review Letters. 59 (1987), H. 10}, isbn = {0031-9007}, pages = {1128 -- 1131}, year = {1987}, language = {en} } @article{JerominWelsch1995, author = {Jeromin, G{\"u}nter Erich and Welsch, Volker}, title = {Diketene a New Esterification Reagent in the Enzyme-Aided Synthesis of Chiral Alcohols and Chiral Acetoacetic Acid Esters}, series = {Tetrahedron Letters . 36 (1995), H. 37}, journal = {Tetrahedron Letters . 36 (1995), H. 37}, isbn = {0040-4039}, pages = {6663 -- 6664}, year = {1995}, language = {en} } @article{BaumannLaraHubbertenetal.1997, author = {Baumann, Marcus and Lara, R.J. and Hubberten, D.N. and Thomas, D.N.}, title = {Dissolved organic matter studies in enclosed systems: Application of hydophobic fractionation for the assessment of organic nitrogen dynamics / Lara, R.J. ; Hubberten, U. ; Thomas, D.N. ; Baumann, M.E.M. ; Kattner, G.}, series = {Journal of Marine Systems. 13 (1997), H. 1-4}, journal = {Journal of Marine Systems. 13 (1997), H. 1-4}, isbn = {0924-7963}, pages = {155 -- 161}, year = {1997}, language = {en} } @article{BaumannTillmannAletsee1989, author = {Baumann, Marcus and Tillmann, U. and Aletsee, L.}, title = {Distribution of Carbon Among Photosynthetic End Products in the Bloom-Forming Arctic Diatom Thalassiosira antarctica COMBER / Tillmann, U. ; Baumann, M.E.M. ; Aletsee, L.}, series = {Polar Biology. 10 (1989), H. 3}, journal = {Polar Biology. 10 (1989), H. 3}, isbn = {0722-4060}, pages = {231 -- 238}, year = {1989}, language = {en} } @article{BaumannGradinger1991, author = {Baumann, Marcus and Gradinger, R.}, title = {Distribution of Phytoplankton Communities in Relation to the Large Scale Hydrographical Regime in the Fram Strait 1984 / Gradinger, R. ; Baumann, M.E.M.}, series = {Marine Biology. 111 (1991), H. 2}, journal = {Marine Biology. 111 (1991), H. 2}, isbn = {0025-3162}, pages = {311 -- 321}, year = {1991}, language = {en} } @article{BongaertsEsserLorbachetal.2011, author = {Bongaerts, Johannes and Esser, Simon and Lorbach, Volker and Al-Momani, L{\´o}ay and M{\"u}ller, Michael A. and Franke, Dirk and Grondal, Christoph and Kurutsch, Anja and Bujnicki, Robert and Takors, Ralf and Raeven, Leon and Wubbolts, Marcel and Bovenberg, Roel and Nieger, Martin and Sch{\"u}rmann, Melanie and Trachtmann, Natalie and Kozak, Stefan and Sprenger, Georg A. and M{\"u}ller, Michael}, title = {Diversity-oriented production of metabolites derived from chorismate and their use in organic synthesis}, series = {Angewandte Chemie International Edition}, volume = {Vol. 50}, journal = {Angewandte Chemie International Edition}, number = {Iss. 34}, publisher = {Wiley}, address = {Weinheim}, issn = {1521-3773 (E-Journal); 0570-0833 (Print); 1433-7851 (Print)}, pages = {7781 -- 7786}, year = {2011}, language = {en} } @article{SeiblerSchuebelerFieringetal.1998, author = {Seibler, Jost and Sch{\"u}beler, Dirk and Fiering, Steven and Groudine, Mark and Bode, J{\"u}rgen}, title = {DNA cassette exchange in ES cells mediated by Flp recombinase: an efficient strategy for repeated modification of tagged loci by marker-free constructs}, series = {Biochemistry}, volume = {37}, journal = {Biochemistry}, number = {18}, issn = {1520-4995}, doi = {10.1021/bi980288t}, pages = {6229 -- 6234}, year = {1998}, language = {en} } @article{SeiblerBode1997, author = {Seibler, Jost and Bode, J{\"u}rgen}, title = {Double-reciprocal crossover mediated by FLP-recombinase: a concept and an assay}, series = {Biochemistry}, volume = {36}, journal = {Biochemistry}, number = {7}, issn = {1520-4995}, pages = {1740 -- 1747}, year = {1997}, language = {en} } @article{GrafSteinhofLotzetal.2009, author = {Graf, Alain-Michel and Steinhof, Rafael and Lotz, Martin and Tippk{\"o}tter, Nils and Kasper, Cornelia and Beutel, Sascha and Ulber, Roland}, title = {Downstream-Processing mit Membranadsorbern zur Isolierung nativer Proteinfraktionen aus Kartoffelfruchtwasser}, series = {Chemie Ingenieur Technik}, volume = {81}, journal = {Chemie Ingenieur Technik}, number = {3}, publisher = {Wiley}, address = {Weinheim}, doi = {10.1002/cite.200800139}, pages = {267 -- 274}, year = {2009}, abstract = {Bei der St{\"a}rkeproduktion entstehendes Kartoffelfruchtwasser besitzt mit 2 - 3 \% einen hohen Anteil an ern{\"a}hrungsphysiologisch interessanten Proteinen. Die industrielle Gewinnung dieser Proteinfracht liefert jedoch lediglich ein minderwertiges, denaturiertes Produkt. Mit Hilfe der Membranadsorber-Technologie lassen sich aus Kartoffelfruchtwasser unter milden Reaktionsbedingungen native bioaktive Proteinfraktionen gewinnen. Geeignete Trennbedingungen wurden im Labormaßstab entwickelt und in den Technikumsmaßstab {\"u}bertragen. An Anionenaustauscher-Membranadsorbern mit einer Membranfl{\"a}che von 10 000 cm2 wurde eine Patatinhaltige Fraktion (44 kDa) mit Bindungskapazit{\"a}ten von 0,37 mg/cm2 isoliert. Eine niedermolekulare Proteinfraktion mit Protease-Inhibitoren konnte durch Kationenaustauscher-Membranadsorber mit Bindungskapazit{\"a}ten von 1,00 mg/cm2 gewonnen werden. Sie ist f{\"u}r verschiedenste Applikationen in der pharmazeutischen, kosmetischen und der Nahrungsmittelindustrie interessant z. B. f{\"u}r Appetitz{\"u}gler oder muskelaufbauende Proteinpr{\"a}parate. Der Aufreinigung der nativen Proteinfraktionen durch Ultra-/Diafiltration schließt sich die Konfektionierung durch Spr{\"u}htrocknung an. Die bioanalytische Charakterisierung der Produkte belegt die Reinheit und die enzymatische Aktivit{\"a}t sowie die Abreicherung von St{\"o}rkomponenten wie Glykoalkaloide und Polyphenoloxidasen.}, language = {de} } @article{StanleyHorsburghRossetal.2009, author = {Stanley, Lesley A. and Horsburgh, Brian C. and Ross, Jillian and Scheer, Nico and Wolf, C. Roland}, title = {Drug transporters: Gatekeepers controlling access of xenobiotics to the cellular interior}, series = {Drug Metabolism Reviews}, volume = {41}, journal = {Drug Metabolism Reviews}, number = {1}, publisher = {Taylor \& Francis}, address = {London}, issn = {1097-9883}, doi = {10.1080/03602530802605040}, pages = {27 -- 65}, year = {2009}, language = {en} } @article{PrielmeierMerboldtHanickeetal.1993, author = {Prielmeier, Franz and Merboldt, K. D. and Hanicke, W. and Frahm, J.}, title = {Dynamic high-resolution MR imaging of brain deoxygenation during transient anoxia in the anesthetized rat}, series = {Journal of cerebral blood flow and metabolism. 13 (1993), H. 5}, journal = {Journal of cerebral blood flow and metabolism. 13 (1993), H. 5}, isbn = {0271-678X}, pages = {889 -- 894}, year = {1993}, language = {en} } @article{PrielmeierNagatomoWicketal.1995, author = {Prielmeier, Franz and Nagatomo, Yasushi and Wick, Markus and Frahm, Jens}, title = {Dynamic monitoring of cerebral metabolites during and after transient global ischemia in rats by quantitative proton NMR spectroscopy in vivo / Yasushi Nagatomo, Markus Wick, Franz Prielmeier, Jens Frahm}, series = {NMR in Biomedicine. 8 (1995), H. 6}, journal = {NMR in Biomedicine. 8 (1995), H. 6}, isbn = {1099-1492}, pages = {265 -- 270}, year = {1995}, language = {en} } @article{AbulnagaPinkenburgSchiffelsetal.2013, author = {Abulnaga, El-Hussiny and Pinkenburg, Olaf and Schiffels, Johannes and E-Refai, Ahmed and Buckel, Wolfgang and Selmer, Thorsten}, title = {Effect of an Oxygen-Tolerant Bifurcating Butyryl Coenzyme A Dehydrogenase/Electron-Transferring Flavoprotein Complex from Clostridium difficile on Butyrate Production in Escherichia coli}, series = {Journal of bacteriology}, volume = {195}, journal = {Journal of bacteriology}, number = {16}, issn = {1098-5530 [E-Journal]}, pages = {3704 -- 3713}, year = {2013}, language = {en} } @article{HeinzeMangPopescuetal.2016, author = {Heinze, D. and Mang, Thomas and Popescu, C. and Weichold, O.}, title = {Effect of side chain length and degree of polymerization on the decomposition and crystallization behaviour of chlorinated poly(vinyl ester) oligomers}, series = {Thermochimica Acta}, volume = {637}, journal = {Thermochimica Acta}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0040-6031 (electronic)}, doi = {10.1016/j.tca.2016.05.015}, pages = {143 -- 153}, year = {2016}, abstract = {Four members of a homologous series of chlorinated poly(vinyl ester) oligomers CCl₃-(CH₂CH (OCO(CH₂)ₘCH₃))ₙ-Cl with degrees of polymerization of 10 and 20 were prepared by telomerisation using carbon tetrachloride. The number of side chain carbon atoms ranges from 2 (poly(vinyl acetate) to 18 (poly(vinyl stearate)). The effect of the n-alkyl side chain length and of the degree of polymerization on the thermal stability and crystallization behaviour of the synthesized compounds was investigated. All oligomers degrade in two major steps by first losing HCl and side chains with subsequent breakdown of the backbone. The members with short side chains, up to poly(vinyl octanoate), are amorphous and show internal plasticization, whereas those with high number of side chain carbon atoms are semi-crystalline due to side-chain crystallization. A better packing for poly(vinyl stearate) is also noticeable. The glass transition and melting temperatures as well as the onset temperature of decomposition are influenced to a larger extent by the side chain length than by the degree of polymerization. Thermal stability is improved if both the size and number of side chains increase, but only a long side chain causes a significant increase of the resistance to degradation. This results in a stabilization of PVAc so that oligomers from poly(vinyl octanoate) on are stable under atmospheric conditions. Thus, the way to design stable, chlorinated PVEs oligomers is to use a long n-alkyl side chain.}, language = {en} } @article{CehreliAkpinarTemizArtmannetal.2015, author = {Cehreli, Ruksan and Akpinar, Hale and Temiz Artmann, Ayseg{\"u}l and Sagol, Ozgul}, title = {Effects of Glutamine and Omega-3 Fatty Acids on Erythrocyte Deformability and Oxidative Damage in Rat Model of Enterocolitis}, series = {Gastroenterology Research}, volume = {8}, journal = {Gastroenterology Research}, number = {5}, issn = {1918-2813}, doi = {10.14740/gr683w}, pages = {265 -- 273}, year = {2015}, language = {en} } @article{BaumannThomasGleitz1992, author = {Baumann, Marcus and Thomas, D. and Gleitz, M.}, title = {Efficiency of carbon assimilation and photoacclimation in a small unicellular Chaetoceros species from the Weddel Sea (Antarctica): Influence of temperature and irridiance / Thomas, D. ; Baumann, M.E.M. ; Gleitz, M.}, series = {Journal of Experimental Marine Biology and Ecology. 157 (1992), H. 2}, journal = {Journal of Experimental Marine Biology and Ecology. 157 (1992), H. 2}, isbn = {0022-0981}, pages = {195 -- 209}, year = {1992}, language = {en} } @article{IberSchuebelerSeibleretal.1998, author = {Iber, Michaela and Sch{\"u}beler, Dirk and Seibler, Jost and H{\"o}xter, Maria and Bode, J{\"u}rgen}, title = {Efficient FACS selection procedure for cells undergoing Flp-mediated site-specific conversions}, series = {Technical Tips Online}, volume = {4}, journal = {Technical Tips Online}, number = {1}, doi = {10.1016/S1366-2120(08)70132-6}, pages = {25 -- 29}, year = {1998}, language = {en} } @article{MeyerStorkKalbeKuropkaetal.1988, author = {Meyer-Stork, L. Sebastian and Kalbe, Jochen and Kuropka, Rolf and Sauter, S. L. and H{\"o}cker, Hartwig and Berndt, Heinz}, title = {Eindeutige Provenienzanalyse von Wolle und feinen Tierhaaren mit Hilfe der Erbsubstanz (DNS)}, series = {Textilveredlung : schweizerische Zeitschrift f{\"u}r Textilchemie, Textilveredlung und deren Randgebiete}, volume = {23}, journal = {Textilveredlung : schweizerische Zeitschrift f{\"u}r Textilchemie, Textilveredlung und deren Randgebiete}, number = {9}, issn = {0040-5310}, pages = {304 -- 307}, year = {1988}, language = {de} } @article{KotterKirchRiekert1984, author = {Kotter, Michael and Kirch, M. and Riekert, Lothar}, title = {Einfluß von Dispersion und Vorgeschichte dispersen Nickels auf dessen katalytische Eigenschaften bei der Hydrierung von Benzol, CO2 und CO / R. Kirch ; M. Kotter ; L. Riekert}, series = {Berichte der Bunsen-Gesellschaft f{\"u}r Physikalische Chemie. 88 (1984)}, journal = {Berichte der Bunsen-Gesellschaft f{\"u}r Physikalische Chemie. 88 (1984)}, isbn = {0005-9021}, pages = {1054 -- 1057}, year = {1984}, language = {de} } @article{Mang2003, author = {Mang, Thomas}, title = {Elastomere zum Abdichten gegen dr{\"u}ckendes Wasser}, series = {Summaries : June 30 to July 3, 2003, N{\"u}rnberg = Kurzfassungen}, journal = {Summaries : June 30 to July 3, 2003, N{\"u}rnberg = Kurzfassungen}, publisher = {DKG, Dt. Kautschuk-Ges.}, address = {Frankfurt, Main}, pages = {121 -- 123}, year = {2003}, language = {de} } @article{Mang2004, author = {Mang, Thomas}, title = {Elastomere zum Abdichten gegen dr{\"u}ckendes Wasser}, series = {Kautschuk Gummi Kunststoffe. 57 (2004), H. 4}, journal = {Kautschuk Gummi Kunststoffe. 57 (2004), H. 4}, isbn = {0022-9520}, pages = {172 -- 178}, year = {2004}, language = {de} } @article{SchererSrivastavaSinghetal.2006, author = {Scherer, Ulrich W. and Srivastava, Alok and Singh, Vivendra and Chandra, Amita}, title = {Electrical conductivity studies of swift heavy ion modified PVC and PVC-PANI composite / Alok Srivastava ,Virendra Singh, Amita Chandra, K.Witte, U.W.Scherer and T.V.Singh}, series = {Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms. 245 (2006), H. 1}, journal = {Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms. 245 (2006), H. 1}, isbn = {0168-583X}, pages = {277 -- 280}, year = {2006}, language = {en} } @article{BaeckerDellePoghossianetal.2011, author = {B{\"a}cker, Matthias and Delle, L. and Poghossian, Arshak and Biselli, Manfred and Zang, Werner and Wagner, P. and Sch{\"o}ning, Michael Josef}, title = {Electrochemical sensor array for bioprocess monitoring}, series = {Electrochimica Acta (2011)}, volume = {56}, journal = {Electrochimica Acta (2011)}, number = {26}, publisher = {Elsevier}, address = {Amsterdam}, pages = {9673 -- 9678}, year = {2011}, language = {en} } @article{ElbersLehmann1985, author = {Elbers, Gereon and Lehmann, G.}, title = {Electron Paramagnetic Resonance and Optical Absorption Spectra of VO2+ in CsCl Single Crystals}, series = {Zeitschrift f{\"u}r Naturforschung / Section A, a journal of physical sciences. 40 (1985)}, journal = {Zeitschrift f{\"u}r Naturforschung / Section A, a journal of physical sciences. 40 (1985)}, isbn = {0932-0784}, pages = {511}, year = {1985}, language = {en} } @article{ElbersLehmann1985, author = {Elbers, Gereon and Lehmann, G.}, title = {Electron paramagnetic resonance of Vanadyl ion impurities in crystalline solids: A comment}, series = {Journal of Physics and Chemistry of Solids. 46 (1985), H. 6}, journal = {Journal of Physics and Chemistry of Solids. 46 (1985), H. 6}, isbn = {0022-3697}, pages = {761}, year = {1985}, language = {en} } @article{CesariRennekampffVinterstenetal.2004, author = {Cesari, Francesca and Rennekampff, Verena and Vintersten, Kristina and Vuong, Lam Giang and Seibler, Jost and Bode, J{\"u}rgen and Wiebel, Franziska F. and Nordheim, Alfred}, title = {Elk-1 knock-out mice engineered by Flp recombinase-mediated cassette exchange}, series = {Genesis : The Journal of Genetics and Development}, volume = {38}, journal = {Genesis : The Journal of Genetics and Development}, number = {2}, issn = {1526-968X}, doi = {10.1002/gene.20003}, pages = {87 -- 92}, year = {2004}, language = {en} } @article{MuellerBeckersMussmannetal.2018, author = {M{\"u}ller, Janina and Beckers, Mario and Mußmann, Nina and Bongaerts, Johannes and B{\"u}chs, Jochen}, title = {Elucidation of auxotrophic deficiencies of Bacillus pumilus DSM 18097 to develop a defined minimal medium}, series = {Microbial Cell Factories}, volume = {17}, journal = {Microbial Cell Factories}, number = {1}, publisher = {BioMed Central}, issn = {1475-2859}, doi = {10.1186/s12934-018-0956-1}, pages = {Article No. 106}, year = {2018}, abstract = {Background Culture media containing complex compounds like yeast extract or peptone show numerous disadvantages. The chemical composition of the complex compounds is prone to significant variations from batch to batch and quality control is difficult. Therefore, the use of chemically defined media receives more and more attention in commercial fermentations. This concept results in better reproducibility, it simplifies downstream processing of secreted products and enable rapid scale-up. Culturing bacteria with unknown auxotrophies in chemically defined media is challenging and often not possible without an extensive trial-and-error approach. In this study, a respiration activity monitoring system for shake flasks and its recent version for microtiter plates were used to clarify unknown auxotrophic deficiencies in the model organism Bacillus pumilus DSM 18097. Results Bacillus pumilus DSM 18097 was unable to grow in a mineral medium without the addition of complex compounds. Therefore, a rich chemically defined minimal medium was tested containing basically all vitamins, amino acids and nucleobases, which are essential ingredients of complex components. The strain was successfully cultivated in this medium. By monitoring of the respiration activity, nutrients were supplemented to and omitted from the rich chemically defined medium in a rational way, thus enabling a systematic and fast determination of the auxotrophic deficiencies. Experiments have shown that the investigated strain requires amino acids, especially cysteine or histidine and the vitamin biotin for growth. Conclusions The introduced method allows an efficient and rapid identification of unknown auxotrophic deficiencies and can be used to develop a simple chemically defined tailor-made medium. B. pumilus DSM 18097 was chosen as a model organism to demonstrate the method. However, the method is generally suitable for a wide range of microorganisms. By combining a systematic combinatorial approach based on monitoring the respiration activity with cultivation in microtiter plates, high throughput experiments with high information content can be conducted. This approach facilitates media development, strain characterization and cultivation of fastidious microorganisms in chemically defined minimal media while simultaneously reducing the experimental effort.}, language = {en} } @article{KruegerGroetzingerBerndt1987, author = {Kr{\"u}ger, G{\"o}tz and Gr{\"o}tzinger, Joachim and Berndt, Heinz}, title = {Enantiomeric resolution of amino acid derivatives on chiral stationary phases by high-performance liquid chromatography}, series = {Journal of Chromatography A}, volume = {1987}, journal = {Journal of Chromatography A}, number = {397}, issn = {0021-9673}, doi = {10.1016/S0021-9673(01)85005-6}, pages = {223 -- 232}, year = {1987}, language = {en} } @article{DuennwaldDemirSiegertetal.2000, author = {D{\"u}nnwald, Thomas and Demir, Ayhan S. and Siegert, Petra and Pohl, Martina and M{\"u}ller, Michael}, title = {Enantioselective Synthesis of (S)-2-Hydroxypropanone Derivatives by Benzoylformate Decarboxylase Catalyzed C-C Bond Formation}, series = {European journal of organic chemistry}, volume = {Vol. 2000}, journal = {European journal of organic chemistry}, number = {Iss. 11}, issn = {0365-5490 (E-Journal); 1099-0690 (E-Journal); 0075-4617 (Print); 0170-2041 (Print); 0947-3440 (Print); 1434-193X (Print); 1434-243X (Print)}, pages = {2161 -- 2170}, year = {2000}, language = {en} } @article{Feuerriegel1998, author = {Feuerriegel, Uwe}, title = {Energetische Verwertung von Kunststoffabf{\"a}llen}, series = {Chemie und Technologie makromolekularer Stoffe :, 16. Kolloquium. / Fachhochschule / Fachbereich Chemieingenieurwesen. 20. November 1998 an der FH Aachen, Fachbereich Chemieingenieurwesen}, journal = {Chemie und Technologie makromolekularer Stoffe :, 16. Kolloquium. / Fachhochschule / Fachbereich Chemieingenieurwesen. 20. November 1998 an der FH Aachen, Fachbereich Chemieingenieurwesen}, publisher = {Fachhochschule Aachen}, address = {Aachen}, pages = {169 -- 189}, year = {1998}, language = {de} } @article{ManeaLeursOrbanetal.2011, author = {Manea, Marilena and Leurs, Ulrike and Orban, Erika and Baranyai, Zsuzsa and {\"O}hlschl{\"a}ger, Peter and Marquardt, Andreas and Schulcz, Akos and Tejeda, Miguel}, title = {Enhanced Enzymatic Stability and Antitumor Activity of Daunorubicin-GnRH-III Bioconjugates Modified in Position 4}, series = {Bioconjugate Chemistry}, volume = {22}, journal = {Bioconjugate Chemistry}, number = {7}, publisher = {ACS}, address = {Washington, DC}, isbn = {1520-4812}, pages = {1320 -- 1329}, year = {2011}, language = {en} } @article{GerigkMaassKreutzeretal.2002, author = {Gerigk, M. and Maaß, D. and Kreutzer, A. and Sprenger, G. and Bongaerts, Johannes and Wubbolts, Marcel and Takors, Ralf}, title = {Enhanced pilot-scale fed-batch L-phenylalanine production with recombinant Escherichia coli by fully integrated reactive extraction}, series = {Bioprocess and biosystems engineering}, volume = {Vol. 25}, journal = {Bioprocess and biosystems engineering}, number = {Iss. 1}, issn = {1432-0797 (E-Journal); 1615-7605 (E-Journal); 0178-515X (Print); 1615-7591 (Print)}, pages = {43 -- 52}, year = {2002}, language = {en} } @article{PlumMaHampeletal.2006, author = {Plum, Leona and Ma, Xiaosong and Hampel, Brigitte and Balthasar, Nina and Coppari, Roberto and M{\"u}nzberg, Heike and Shanabrough, Marya and Burdakov, Denis and Rother, Eva and Janoschek, Ruth and Alber, Jens and Belgardt, Bengt F. and Koch, Linda and Seibler, Jost and Schenk, Frieder and Fekete, Csaba and Suzuki, Akira and Mak, Tak W. and Krone, Wilhelm and Horvath, Tamas L. and Ashcroft, Frances M. and Br{\"u}ning, Jens C.}, title = {Enhanced PIP3 signaling in POMC neurons causes KATP channel activation and leads to diet-sensitive obesity}, series = {The Journal of Clinical Investigation (JCI)}, volume = {116}, journal = {The Journal of Clinical Investigation (JCI)}, number = {7}, issn = {1558-8238}, doi = {10.1172/JCI27123}, pages = {1886 -- 1901}, year = {2006}, language = {en} } @article{OehlschlaegerQuettingAlvarezetal.2009, author = {{\"O}hlschl{\"a}ger, Peter and Quetting, Michael and Alvarez, Gerardo and D{\"u}rst, Matthias and Gissmann, Lutz and Kaufmann, Andreas M.}, title = {Enhancement of immunogenicity of a therapeutic cervical cancer DNA-based vaccine by co-application of sequence-optimized genetic adjuvants}, series = {International Journal of Cancer}, volume = {125}, journal = {International Journal of Cancer}, number = {1}, publisher = {Wiley}, address = {Weinheim}, isbn = {1097-0215}, pages = {189 -- 198}, year = {2009}, language = {en} } @article{KotterRiekertTurek1989, author = {Kotter, Michael and Riekert, Lothar and Turek, Thomas}, title = {Entfernung von Ammoniak aus Abw{\"a}ssern durch Strippung und Sorption an Zeolithen : [Synopse 1724]}, series = {Chemie - Ingenieur - Technik. 61 (1989), H. 1}, journal = {Chemie - Ingenieur - Technik. 61 (1989), H. 1}, isbn = {0009-286X}, pages = {74 -- 75}, year = {1989}, language = {de} } @article{MangHaulenaBrill1997, author = {Mang, Thomas and Haulena, Friedhelm and Brill, B.}, title = {Entsorgung beflockter Verbundwerkstoffe}, series = {Flock 97 : 14. Internationales Flockseminar Seeheim bei Darmstadt 16. - 17. Januar 1997.}, journal = {Flock 97 : 14. Internationales Flockseminar Seeheim bei Darmstadt 16. - 17. Januar 1997.}, publisher = {Flock-Verl.}, address = {B{\"u}dingen}, pages = {10-1 -- 10-18}, year = {1997}, language = {de} } @article{BiselliBaeckerPoghossianetal.2010, author = {Biselli, Manfred and B{\"a}cker, Matthias and Poghossian, Arshak and Sch{\"o}ning, Michael Josef and Schnitzler, Thomas and Zang, Werner and Wagner, P.}, title = {Entwicklung eines modularen festk{\"o}rperbasierten Sensorsystems f{\"u}r die {\"U}berwachung von Zellkulturfermenationen}, series = {Sensoren und Messsysteme 2010 [Elektronische Ressource] : Vortr{\"a}ge der 15. ITG/GMA-Fachtagung vom 18. bis 19. Mai 2010 in N{\"u}rnberg / Informationstechnische Gesellschaft im VDE (ITG); VDI/VDE-Gesellschaft Mess- und Automatisierungstechnik (GMA)}, journal = {Sensoren und Messsysteme 2010 [Elektronische Ressource] : Vortr{\"a}ge der 15. ITG/GMA-Fachtagung vom 18. bis 19. Mai 2010 in N{\"u}rnberg / Informationstechnische Gesellschaft im VDE (ITG); VDI/VDE-Gesellschaft Mess- und Automatisierungstechnik (GMA)}, publisher = {VDE Verlag}, address = {Berlin}, isbn = {978-3-8007-3260-9}, pages = {688 -- 691}, year = {2010}, language = {de} } @article{DeppeBongaertsO'Connelletal.2011, author = {Deppe, Veronika Maria and Bongaerts, Johannes and O'Connell, Timothy and Maurer, Karl-Heinz and Meinhardt, Friedhelm}, title = {Enzymatic deglycation of Amadori products in bacteria}, series = {Applied microbiology and biotechnology}, volume = {Vol. 90}, journal = {Applied microbiology and biotechnology}, number = {Iss. 2}, publisher = {Springer}, address = {Berlin}, issn = {1432-0614 (E-Journal); 0171-1741 (Print); 0175-7598 (Print); 0340-2118 (Print)}, pages = {399 -- 406}, year = {2011}, language = {en} } @article{TippkoetterDuweWiesenetal.2014, author = {Tippk{\"o}tter, Nils and Duwe, Anna-Maria and Wiesen, Sebastian and Sieker, Tim and Ulber, Roland}, title = {Enzymatic hydrolysis of beech wood lignocellulose at high solid contents and its utilization as substrate for the production of biobutanol and dicarboxylic acids}, series = {Bioresource Technology}, volume = {167}, journal = {Bioresource Technology}, publisher = {Elsevier}, address = {Amsterdam}, doi = {10.1016/j.biortech.2014.06.052}, pages = {447 -- 455}, year = {2014}, abstract = {The development of a cost-effective hydrolysis for crude cellulose is an essential part of biorefinery developments. To establish such high solid hydrolysis, a new solid state reactor with static mixing is used. However, concentrations >10\% (w/w) cause a rate and yield reduction of enzymatic hydrolysis. By optimizing the synergetic activity of cellulolytic enzymes at solid concentrations of 9\%, 17\% and 23\% (w/w) of crude Organosolv cellulose, glucose concentrations of 57, 113 and 152 g L⁻¹ are reached. However, the glucose yield decreases from 0.81 to 0.72gg⁻¹ at 17\% (w/w). Optimal conditions for hydrolysis scale-up under minimal enzyme addition are identified. As result, at 23\% (w/w) crude cellulose the glucose yield increases from 0.29 to 0.49gg⁻¹. As proof of its applicability, biobutanol, succinic and itaconic acid are produced with the crude hydrolysate. The potential of the substrate is proven e.g. by a high butanol yield of 0.33gg⁻¹.}, language = {en} } @article{JerominWeise1990, author = {Jeromin, G{\"u}nter Erich and Weise, Sven}, title = {Enzymatische Acetylierung von (±)-1-Phthalimido-2-propanol}, series = {Liebigs Annalen der Chemie (1990)}, journal = {Liebigs Annalen der Chemie (1990)}, isbn = {0947-3440}, pages = {1045 -- 1046}, year = {1990}, language = {de} }