@inproceedings{HunsdiekChwallek2019, author = {Hunsdiek, Niklas J.A. and Chwallek, Constanze}, title = {External venturing activities and the influence of the chief technology officer}, series = {G-Forum Jahreskonferenz 2019}, booktitle = {G-Forum Jahreskonferenz 2019}, pages = {6 Seiten}, year = {2019}, language = {en} } @inproceedings{HingleyDikta2019, author = {Hingley, Peter and Dikta, Gerhard}, title = {Finding a well performing box-jenkins forecasting model for annualised patent filings counts}, series = {International Symposium on Forecasting, Thessaloniki, Greece, June 2019}, booktitle = {International Symposium on Forecasting, Thessaloniki, Greece, June 2019}, pages = {24 Folien}, year = {2019}, language = {en} } @incollection{LeiseAltherrSimonetal.2019, author = {Leise, Philipp and Altherr, Lena and Simon, Nicolai and Pelz, Peter F.}, title = {Finding global-optimal gearbox designs for battery electric vehicles}, series = {Optimization of complex systems - theory, models, algorithms and applications : WCGO 2019}, booktitle = {Optimization of complex systems - theory, models, algorithms and applications : WCGO 2019}, publisher = {Springer}, address = {Cham}, isbn = {978-3-030-21802-7}, doi = {10.1007/978-3-030-21803-4_91}, pages = {916 -- 925}, year = {2019}, abstract = {In order to maximize the possible travel distance of battery electric vehicles with one battery charge, it is mandatory to adjust all components of the powertrain carefully to each other. While current vehicle designs mostly simplify the powertrain rigorously and use an electric motor in combination with a gearbox with only one fixed transmission ratio, the use of multi-gear systems has great potential. First, a multi-speed system is able to improve the overall energy efficiency. Secondly, it is able to reduce the maximum momentum and therefore to reduce the maximum current provided by the traction battery, which results in a longer battery lifetime. In this paper, we present a systematic way to generate multi-gear gearbox designs that—combined with a certain electric motor—lead to the most efficient fulfillment of predefined load scenarios and are at the same time robust to uncertainties in the load. Therefore, we model the electric motor and the gearbox within a Mixed-Integer Nonlinear Program, and optimize the efficiency of the mechanical parts of the powertrain. By combining this mathematical optimization program with an unsupervised machine learning algorithm, we are able to derive global-optimal gearbox designs for practically relevant momentum and speed requirements.}, language = {en} } @article{EngelBayerHoltmannetal.2019, author = {Engel, Mareike and Bayer, Hendrik and Holtmann, Dirk and Tippk{\"o}tter, Nils and Ulber, Roland}, title = {Flavin secretion of Clostridium acetobutylicum in a bioelectrochemical system - Is an iron limitation involved?}, series = {Bioelectrochemistry}, journal = {Bioelectrochemistry}, number = {In Press, Accepted Manuscript}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1567-5394}, doi = {10.1016/j.bioelechem.2019.05.014}, year = {2019}, language = {en} } @inproceedings{FunkeBeckmann2019, author = {Funke, Harald and Beckmann, Nils}, title = {Flexible Fuel Operation of a Dry-Low-Nox Micromix Combustor with Variable Hydrogen Methane Mixtures}, series = {Proceedings of International Gas Turbine Congress 2019 Tokyo, November 17-22, 2019, Tokyo, Japan}, booktitle = {Proceedings of International Gas Turbine Congress 2019 Tokyo, November 17-22, 2019, Tokyo, Japan}, isbn = {978-4-89111-010-9}, year = {2019}, language = {en} } @inproceedings{GrundmannBauerBodenetal.2019, author = {Grundmann, Jan Thimo and Bauer, Waldemar and Boden, Ralf and Ceriotti, Matteo and Chand, Suditi and Cordero, Federico and Dachwald, Bernd and Dumont, Etienne and Grimm, Christian D. and Heiligers, Jeannette and Herč{\´i}k, David and H{\´e}rique, Alain and Ho, Tra-Mi and Jahnke, Rico and Kofman, Wlodek and Lange, Caroline and Lichtenheldt, Roy and McInnes, Colin and Meß, Jan-Gerd and Mikschl, Tobias and Mikulz, Eugen and Montenegro, Sergio and Moore, Iain and Pelivan, Ivanka and Peloni, Alessandro and Plettemeier, Dirk and Quantius, Dominik and Reershemius, Siebo and Renger, Thomas and Riemann, Johannes and Rogez, Yves and Ruffer, Michael and Sasaki, Kaname and Schmitz, Nicole and Seboldt, Wolfgang and Seefeldt, Patric and Spietz, Peter and Spr{\"o}witz, Tom and Sznajder, Maciej and T{\´o}th, Norbert and Vergaaij, Merel and Viavattene, Giulia and Wejmo, Elisabet and Wiedemann, Carsten and Wolff, Friederike and Ziach, Christian}, title = {Flights are ten a sail - Re-use and commonality in the design and system engineering of small spacecraft solar sail missions with modular hardware for responsive and adaptive exploration}, series = {70th International Astronautical Congress (IAC)}, booktitle = {70th International Astronautical Congress (IAC)}, isbn = {9781713814856}, pages = {1 -- 7}, year = {2019}, language = {en} } @inproceedings{ChavezBermudezWollert2019, author = {Chavez Bermudez, Victor Francisco and Wollert, J{\"o}rg}, title = {Gateway for Automation Controllers and Cloud based Voice Recognition Services}, series = {KommA, 10. Jahreskolloquium Kommunikation in der Automation}, booktitle = {KommA, 10. Jahreskolloquium Kommunikation in der Automation}, publisher = {Institut f{\"u}r Automation und Kommunikation}, address = {Magdeburg}, organization = {KommA, 2019, Jahreskolloquium Kommunikation in der Automation, 10., Lemgo, DE, 2019-11-20 - 2019-11-21}, isbn = {978-3-944722-85-6}, pages = {1 -- 8}, year = {2019}, language = {en} } @inproceedings{UlmerBraunLaietal.2019, author = {Ulmer, Jessica and Braun, Sebastian and Lai, Chow Yin and Cheng, Chi-Tsun and Wollert, J{\"o}rg}, title = {Generic integration of VR and AR in product lifecycles based on CAD models}, series = {Proceedings of The 23rd World Multi-Conference on Systemics, Cybernetics and Informatics: WMSCI 2019}, booktitle = {Proceedings of The 23rd World Multi-Conference on Systemics, Cybernetics and Informatics: WMSCI 2019}, year = {2019}, language = {en} } @incollection{DachwaldOhndorf2019, author = {Dachwald, Bernd and Ohndorf, Andreas}, title = {Global optimization of continuous-thrust trajectories using evolutionary neurocontrol}, series = {Modeling and Optimization in Space Engineering}, booktitle = {Modeling and Optimization in Space Engineering}, publisher = {Springer}, address = {Cham}, isbn = {978-3-030-10501-3}, doi = {10.1007/978-3-030-10501-3_2}, pages = {33 -- 57}, year = {2019}, abstract = {Searching optimal continuous-thrust trajectories is usually a difficult and time-consuming task. The solution quality of traditional optimal-control methods depends strongly on an adequate initial guess because the solution is typically close to the initial guess, which may be far from the (unknown) global optimum. Evolutionary neurocontrol attacks continuous-thrust optimization problems from the perspective of artificial intelligence and machine learning, combining artificial neural networks and evolutionary algorithms. This chapter describes the method and shows some example results for single- and multi-phase continuous-thrust trajectory optimization problems to assess its performance. Evolutionary neurocontrol can explore the trajectory search space more exhaustively than a human expert can do with traditional optimal-control methods. Especially for difficult problems, it usually finds solutions that are closer to the global optimum. Another fundamental advantage is that continuous-thrust trajectories can be optimized without an initial guess and without expert supervision.}, language = {en} } @inproceedings{MatareSchifferFerrein2019, author = {Matar{\´e}, Victor and Schiffer, Stefan and Ferrein, Alexander}, title = {golog++ : An integrative system design}, series = {CogRob 2018. Cognitive Robotics Workshop : Proceedings of the 11th Cognitive Robotics Workshop 2018 co-located with 16th International Conference on Principles of Knowledge Representation and Reasoning (KR 2018) Tempe, AZ, USA, October 27th, 2018}, booktitle = {CogRob 2018. Cognitive Robotics Workshop : Proceedings of the 11th Cognitive Robotics Workshop 2018 co-located with 16th International Conference on Principles of Knowledge Representation and Reasoning (KR 2018) Tempe, AZ, USA, October 27th, 2018}, editor = {Steinbauer, Gerald and Ferrein, Alexander}, issn = {1613-0073}, pages = {29 -- 35}, year = {2019}, language = {en} } @inproceedings{LorenzAltherrPelz2019, author = {Lorenz, Imke-Sophie B. and Altherr, Lena and Pelz, Peter F.}, title = {Graph-theoretic resilience analysis of a water distribution system's topology}, series = {World Congress on Resilience, Reliability and Asset Management 2019}, booktitle = {World Congress on Resilience, Reliability and Asset Management 2019}, pages = {106 -- 109}, year = {2019}, abstract = {Water suppliers are faced with the great challenge of achieving high-quality and, at the same time, low-cost water supply. In practice, the focus is set on the most beneficial maintenance measures and/or capacity adaptations of existing water distribution systems (WDS). Since climatic and demographic influences will pose further challenges in the future, the resilience enhancement of WDS, i.e. the enhancement of their capability to withstand and recover from disturbances, has been in particular focus recently. To assess the resilience of WDS, metrics based on graph theory have been proposed. In this study, a promising approach is applied to assess the resilience of the WDS for a district in a major German City. The conducted analysis provides insight into the process of actively influencing the resilience of WDS}, language = {en} } @article{EngelmannSeifertMuesetal.2019, author = {Engelmann, Ulrich M. and Seifert, Julian and Mues, Benedikt and Roitsch, Stefan and M{\´e}nager, Christine and Schmidt, Annette M. and Slabu, Ioana}, title = {Heating efficiency of magnetic nanoparticles decreases with gradual immobilization in hydrogels}, series = {Journal of Magnetism and Magnetic Materials}, volume = {471}, journal = {Journal of Magnetism and Magnetic Materials}, number = {1}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0304-8853}, doi = {10.1016/j.jmmm.2018.09.113}, pages = {486 -- 494}, year = {2019}, language = {en} } @inproceedings{QuitterMarinoBauschat2019, author = {Quitter, Julius and Marino, Matthew and Bauschat, J.-Michael}, title = {Highly Non-Planar Aircraft Configurations: Estimation of Flight Mechanical Derivatives Using Low-Order Methods}, series = {Deutscher Luft- und Raumfahrtkongress 2019, DLRK 2019. Darmstadt, Germany}, booktitle = {Deutscher Luft- und Raumfahrtkongress 2019, DLRK 2019. Darmstadt, Germany}, pages = {10 Seiten}, year = {2019}, language = {en} } @article{DotzauerPfeifferLaueretal.2019, author = {Dotzauer, Martin and Pfeiffer, Diana and Lauer, Markus and Pohl, Marcel and Mauky, Eric and B{\"a}r, Katharina and Sonnleitner, Matthias and Z{\"o}rner, Wilfried and Hudde, Jessica and Schwarz, Bj{\"o}rn and Faßauer, Burkhardt and Dahmen, Markus and Rieke, Christian and Herbert, Johannes and Thr{\"a}n, Daniela}, title = {How to measure flexibility - Performance indicators for demand driven power generation from biogas plants}, series = {Renewable Energy}, journal = {Renewable Energy}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0960-1481}, doi = {10.1016/j.renene.2018.10.021}, pages = {135 -- 146}, year = {2019}, language = {en} } @inproceedings{KazukiKobayashiHirabayashietal.2019, author = {Kazuki, Yasuhiro and Kobayashi, Kaoru and Hirabayashi, Masumi and Abe, Satoshi and Kajitani, Naoyo and Kazuki, Kanoko and Takehara, Shoko and Takiguchi, Masato and Satoh, Daisuke and Kuze, Jiro and Sakuma, Tetsushi and Kaneko, Takehito and Mashimo, Tomoji and Osamura, Minori and Hashimoto, Mari and Wakatsuki, Riko and Hirashima, Rika and Fujiwara, Ryoichi and Deguchi, Tsuneo and Kurihara, Atsushi and Tsukazaki, Yasuko and Senda, Naoto and Yamamoto, Takashi and Scheer, Nico and Oshimura, Mitsuo}, title = {Humanized UGT2 and CYP3A transchromosomic rats for improved prediction of human drug metabolism}, series = {PNAS Proceedings of the National Academy of Sciences of the United States of America}, volume = {116}, booktitle = {PNAS Proceedings of the National Academy of Sciences of the United States of America}, number = {8}, issn = {1091-6490}, doi = {10.1073/pnas.1808255116}, pages = {3072 -- 3081}, year = {2019}, language = {en} } @article{MoraisSilvaDantasetal.2019, author = {Morais, Paulo V. and Silva, Anielle C. A. and Dantas, Noelio O. and Sch{\"o}ning, Michael Josef and Siqueira, Jos{\´e} R., Jr.}, title = {Hybrid Layer-by-Layer Film of Polyelectrolytes-Embedded Catalytic CoFe2O4 Nanocrystals as Sensing Units in Capacitive Electrolyte-Insulator-Semiconductor Devices}, series = {physica status solidi a : applications and materials sciences}, volume = {216}, journal = {physica status solidi a : applications and materials sciences}, number = {1900044}, publisher = {Wiley}, address = {Weinheim}, doi = {10.1002/pssa.201900044}, pages = {1 -- 9}, year = {2019}, language = {en} } @article{Kurz2019, author = {Kurz, Melanie}, title = {Images of Sweden in Germany: from Sundborn and Bullerby to Ikea}, series = {nomad: the magazine for new design culture, business affairs and contemporary lifestyle}, journal = {nomad: the magazine for new design culture, business affairs and contemporary lifestyle}, number = {8}, isbn = {2513-0714}, pages = {136 -- 147}, year = {2019}, language = {en} } @inproceedings{FingerBraunBil2019, author = {Finger, Felix and Braun, Carsten and Bil, Cees}, title = {Impact of Engine Failure Constraints on the Initial Sizing of Hybrid-Electric GA Aircraft}, series = {AIAA Scitech 2019 Forum}, booktitle = {AIAA Scitech 2019 Forum}, doi = {10.2514/6.2019-1812}, year = {2019}, language = {en} } @inproceedings{LudowicyRingsFingeretal.2019, author = {Ludowicy, Jonas and Rings, Ren{\´e} and Finger, Felix and Braun, Carsten and Bil, Cees}, title = {Impact of Propulsion Technology Levels on the Sizing and Energy Consumption for Serial HybridElectric General Aviation Aircraft}, series = {Asia Pacific International Symposium on Aerospace Technology. APISAT 2019}, booktitle = {Asia Pacific International Symposium on Aerospace Technology. APISAT 2019}, pages = {14 Seiten}, year = {2019}, language = {en} } @inproceedings{AuthCzarneckiBensberg2019, author = {Auth, Gunnar and Czarnecki, Christian and Bensberg, Frank}, title = {Impact of robotic process automation on enterprise architectures}, series = {GI Edition Proceedings Band 295 INFORMATIK 2019, Workshop-Beitr{\"a}ge}, booktitle = {GI Edition Proceedings Band 295 INFORMATIK 2019, Workshop-Beitr{\"a}ge}, editor = {Draude, Claude and Lange, Martin and Sick, Bernhard and Gesellschaft f{\"u}r Informatik e.V. (GI),}, publisher = {K{\"o}llen}, address = {Bonn}, isbn = {9783885796893}, issn = {1617-5468}, doi = {10.18420/inf2019_ws05}, pages = {59 -- 65}, year = {2019}, abstract = {The initial idea of Robotic Process Automation (RPA) is the automation of business processes through the presentation layer of existing application systems. For this simple emulation of user input and output by software robots, no changes of the systems and architecture is required. However, considering strategic aspects of aligning business and technology on an enterprise level as well as the growing capabilities of RPA driven by artificial intelligence, interrelations between RPA and Enterprise Architecture (EA) become visible and pose new questions. In this paper we discuss the relationship between RPA and EA in terms of perspectives and implications. As workin- progress we focus on identifying new questions and research opportunities related to RPA and EA.}, language = {en} } @inproceedings{EngemannBadriWenningetal.2019, author = {Engemann, Heiko and Badri, Sriram and Wenning, Marius and Kallweit, Stephan}, title = {Implementation of an Autonomous Tool Trolley in a Production Line}, series = {Advances in Service and Industrial Robotics. RAAD 2019. Advances in Intelligent Systems and Computing, vol 980}, booktitle = {Advances in Service and Industrial Robotics. RAAD 2019. Advances in Intelligent Systems and Computing, vol 980}, publisher = {Springer}, address = {Cham}, isbn = {978-3-030-19648-6}, doi = {10.1007/978-3-030-19648-6_14}, pages = {117 -- 125}, year = {2019}, language = {en} } @inproceedings{SchwagerTeixeiraBouraFleschetal.2019, author = {Schwager, Christian and Teixeira Boura, Cristiano Jos{\´e} and Flesch, Robert and Alexopoulos, Spiros and Herrmann, Ulf}, title = {Improved efficiency prediction of a molten salt receiver based on dynamic cloud passage simulation}, series = {AIP Conference Proceedings}, volume = {2126}, booktitle = {AIP Conference Proceedings}, number = {1}, isbn = {978-0-7354-1866-0}, doi = {10.1063/1.5117566}, pages = {030054-1 -- 030054-8}, year = {2019}, language = {en} } @article{BleilevensHillGrzannaetal.2019, author = {Bleilevens, Christian and Hill, Aileen and Grzanna, Tim and Fechter, Tamara and Bohnen, Melanie and Weber, Hans-Joachim and Beckers, Christian and Borosch, Sebastian and Zayat, Rashad and Benstoem, Carin and Rossaint, Rolf and Goetzenich, Andreas}, title = {In vitro head-to-head comparison of anticoagulation properties of two heparin brands in a human blood miniature mock loop}, series = {Interactive cardiovascular and thoracic surgery}, volume = {28}, journal = {Interactive cardiovascular and thoracic surgery}, number = {1}, issn = {1569-9285}, doi = {10.1093/icvts/ivy206}, pages = {120 -- 127}, year = {2019}, language = {en} } @article{FingerBilBraun2019, author = {Finger, Felix and Bil, Cees and Braun, Carsten}, title = {Initial Sizing Methodology for Hybrid-Electric General Aviation Aircraft}, series = {Journal of Aircraft}, volume = {57}, journal = {Journal of Aircraft}, number = {2}, issn = {1533-3868}, doi = {10.2514/1.C035428}, pages = {245 -- 255}, year = {2019}, language = {en} } @article{MarinkovicButenweg2019, author = {Marinkovic, Marko and Butenweg, Christoph}, title = {Innovative decoupling system for the seismic protection of masonry infill walls in reinforced concrete frames}, series = {Engineering Structures}, volume = {197}, journal = {Engineering Structures}, number = {Article 109435}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0141-0296}, doi = {10.1016/j.engstruct.2019.109435}, year = {2019}, language = {en} } @inproceedings{GerhardsSchleserOttenetal.2019, author = {Gerhards, Benjamin and Schleser, Markus and Otten,, Christian and Schwarz, Alexander and Gebhardt, Andreas}, title = {Innovative Laser Beam Joining Technology for Additive Manufactured Parts}, series = {Conference Proceedings 72nd IIW Annual Assembly and International Conference, 7-12 July 2019, Bratislava}, booktitle = {Conference Proceedings 72nd IIW Annual Assembly and International Conference, 7-12 July 2019, Bratislava}, pages = {1 -- 8}, year = {2019}, language = {en} } @article{SchiedermeierRettnerHeilmannetal.2019, author = {Schiedermeier, Maximilian and Rettner, Cornelius and Heilmann, Marcel and Schneider, Felix and Marz, Martin}, title = {Interference of automotive HV-DC-systems by traction voltage-source-inverters (VSI)}, series = {2019 IEEE Transportation Electrification Conference (ITEC-India)}, journal = {2019 IEEE Transportation Electrification Conference (ITEC-India)}, publisher = {IEEE}, address = {New York}, doi = {10.1109/ITEC-India48457.2019.ITECINDIA2019-37}, pages = {1 -- 6}, year = {2019}, language = {en} } @inproceedings{BragardSubeSchneideretal.2019, author = {Bragard, Michael and Sube, Maike and Schneider, Maike and Jungemann, Christoph}, title = {Introducing a Cross-University Bachelor's Programme with Orientation Semester - Enabling a Permeable Academic Education System}, series = {2019 20th International Conference on Research and Education in Mechatronics (REM)}, booktitle = {2019 20th International Conference on Research and Education in Mechatronics (REM)}, isbn = {978-1-5386-9257-8}, doi = {10.1109/REM.2019.8744132}, pages = {1 -- 6}, year = {2019}, language = {en} } @article{LeschingerBeschAydinetal.2019, author = {Leschinger, Tim and Besch, Katharina and Aydin, Cansu and Staat, Manfred and Scaal, Martin and M{\"u}ller, Lars Peter and Wegmann, Kilian}, title = {Irreparable rotator cuff tears: a biomechanical comparison of superior capsuloligamentous complex reconstruction techniques and an interposition graft technique}, series = {The Orthopaedic Journal of Sports Medicine}, volume = {7}, journal = {The Orthopaedic Journal of Sports Medicine}, number = {8}, doi = {10.1177/2325967119864590}, pages = {1 -- 5}, year = {2019}, language = {en} } @inproceedings{BrockmannSultanowCzarnecki2019, author = {Brockmann, Carsten and Sultanow, Eldar and Czarnecki, Christian}, title = {Is enterprise architecture still relevant in the digital age?}, series = {GI Edition Proceedings Band 295 INFORMATIK 2019, Workshop-Beitr{\"a}ge}, booktitle = {GI Edition Proceedings Band 295 INFORMATIK 2019, Workshop-Beitr{\"a}ge}, editor = {Draude, Claude and Lange, Martin and Sick, Bernhard}, publisher = {K{\"o}llen}, address = {Bonn}, isbn = {9783885796893}, issn = {1617-5468}, doi = {10.18420/inf2019_ws01}, pages = {21 -- 21}, year = {2019}, language = {en} } @inproceedings{KetelhutGoellBraunsteinetal.2019, author = {Ketelhut, Maike and G{\"o}ll, Fabian and Braunstein, Bjoern and Albracht, Kirsten and Abel, Dirk}, title = {Iterative learning control of an industrial robot for neuromuscular training}, series = {2019 IEEE Conference on Control Technology and Applications}, booktitle = {2019 IEEE Conference on Control Technology and Applications}, publisher = {IEEE}, address = {New York}, isbn = {978-1-7281-2767-5 (ePub)}, doi = {10.1109/CCTA.2019.8920659}, pages = {7 Seiten}, year = {2019}, abstract = {Effective training requires high muscle forces potentially leading to training-induced injuries. Thus, continuous monitoring and controlling of the loadings applied to the musculoskeletal system along the motion trajectory is required. In this paper, a norm-optimal iterative learning control algorithm for the robot-assisted training is developed. The algorithm aims at minimizing the external knee joint moment, which is commonly used to quantify the loading of the medial compartment. To estimate the external knee joint moment, a musculoskeletal lower extremity model is implemented in OpenSim and coupled with a model of an industrial robot and a force plate mounted at its end-effector. The algorithm is tested in simulation for patients with varus, normal and valgus alignment of the knee. The results show that the algorithm is able to minimize the external knee joint moment in all three cases and converges after less than seven iterations.}, language = {en} } @article{MeyerGaalenLeschingeretal.2019, author = {Meyer, Carolin and Gaalen, Kerstin van and Leschinger, Tim and Scheyerer, Max J. and Neiss, Wolfram F. and Staat, Manfred and M{\"u}ller, Lars P. and Wegmann, Kilian}, title = {Kyphoplasty of Osteoporotic Fractured Vertebrae: A Finite Element Analysis about Two Types of Cement}, series = {BioMed Research International}, journal = {BioMed Research International}, doi = {10.1155/2019/9232813}, pages = {Article ID 9232813}, year = {2019}, language = {en} } @phdthesis{Tran2019, author = {Tran, Ngoc Trinh}, title = {Limit and Shakedown analysis of structures under stochastic conditions}, publisher = {Technische Universit{\"a}t Braunschweig}, address = {Braunschweig}, doi = {10.24355/dbbs.084-201902121135-0}, pages = {166 S.}, year = {2019}, language = {en} } @article{RoethSlabuKessleretal.2019, author = {Roeth, A.A. and Slabu, I. and Kessler, A. and Engelmann, Ulrich M.}, title = {Local treatment of pancreatic cancer with magnetic nanoparticles}, series = {HPB}, volume = {21}, journal = {HPB}, number = {Supplement 3}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1365-182X}, doi = {10.1016/j.hpb.2019.10.959}, pages = {S868 -- S869}, year = {2019}, language = {en} } @incollection{TippkoetterMoehringRothetal.2019, author = {Tippk{\"o}tter, Nils and M{\"o}hring, Sophie and Roth, Jasmine and Wulfhorst, Helene}, title = {Logistics of lignocellulosic feedstocks: preprocessing as a preferable option}, series = {Biorefineries}, booktitle = {Biorefineries}, publisher = {Springer}, address = {Cham}, isbn = {978-3-319-97117-9}, doi = {10.1007/10_2017_58}, pages = {43 -- 68}, year = {2019}, abstract = {In comparison to crude oil, biorefinery raw materials are challenging in concerns of transport and storage. The plant raw materials are more voluminous, so that shredding and compacting usually are necessary before transport. These mechanical processes can have a negative influence on the subsequent biotechnological processing and shelf life of the raw materials. Various approaches and their effects on renewable raw materials are shown. In addition, aspects of decentralized pretreatment steps are discussed. Another important aspect of pretreatment is the varying composition of the raw materials depending on the growth conditions. This problem can be solved with advanced on-site spectrometric analysis of the material.}, language = {en} } @incollection{StengerAltherrAbel2019, author = {Stenger, David and Altherr, Lena and Abel, Dirk}, title = {Machine learning and metaheuristics for black-box optimization of product families: a case-study investigating solution quality vs. computational overhead}, series = {Operations Research Proceedings 2018}, booktitle = {Operations Research Proceedings 2018}, publisher = {Springer}, address = {Cham}, isbn = {978-3-030-18499-5 (Print)}, doi = {10.1007/978-3-030-18500-8_47}, pages = {379 -- 385}, year = {2019}, abstract = {In product development, numerous design decisions have to be made. Multi-domain virtual prototyping provides a variety of tools to assess technical feasibility of design options, however often requires substantial computational effort for just a single evaluation. A special challenge is therefore the optimal design of product families, which consist of a group of products derived from a common platform. Finding an optimal platform configuration (stating what is shared and what is individually designed for each product) and an optimal design of all products simultaneously leads to a mixed-integer nonlinear black-box optimization model. We present an optimization approach based on metamodels and a metaheuristic. To increase computational efficiency and solution quality, we compare different types of Gaussian process regression metamodels adapted from the domain of machine learning, and combine them with a genetic algorithm. We illustrate our approach on the example of a product family of electrical drives, and investigate the trade-off between solution quality and computational overhead.}, language = {en} } @inproceedings{HailerWeberArent2019, author = {Hailer, Benjamin and Weber, Tobias and Arent, Jan-Christoph}, title = {Manufacturing Process Simulation for Autoclave-Produced Sandwich Structures}, series = {Proceedings of SAMPE Europe Conference 2019, Nantes, France}, booktitle = {Proceedings of SAMPE Europe Conference 2019, Nantes, France}, pages = {1 -- 8}, year = {2019}, language = {en} } @inproceedings{WeberEnglhardHaileretal.2019, author = {Weber, Tobias and Englhard, Markus and Hailer, Benjamin and Arent, Jan-Christoph}, title = {Manufacturing Process Simulation for the Prediction of Tool-Part-Interaction and Ply Wrinkling}, series = {Proceedings of SAMPE Europe Conference 2019, Nantes, France}, booktitle = {Proceedings of SAMPE Europe Conference 2019, Nantes, France}, pages = {1 -- 10}, year = {2019}, language = {en} } @inproceedings{FingerGoettenBraunetal.2019, author = {Finger, Felix and G{\"o}tten, Falk and Braun, Carsten and Bil, Cees}, title = {Mass, Primary Energy, and Cost - The Impact of Optimization Objectives on the Initial Sizing of Hybrid-Electric General Aviation Aircraft}, series = {Deutscher Luft- und Raumfahrtkongress 2019, DLRK 2019. Darmstadt, Germany}, booktitle = {Deutscher Luft- und Raumfahrtkongress 2019, DLRK 2019. Darmstadt, Germany}, doi = {10.25967/490012}, pages = {1 -- 17}, year = {2019}, language = {en} } @article{AchtsnichtSchoenenbornOffenhaeusseretal.2019, author = {Achtsnicht, Stefan and Sch{\"o}nenborn, Kristina and Offenh{\"a}usser, Andreas and Krause, Hans-Joachim}, title = {Measurement of the magnetophoretic velocity of different superparamagnetic beads}, series = {Journal of Magnetism and Magnetic Materials}, volume = {477}, journal = {Journal of Magnetism and Magnetic Materials}, number = {1}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0304-8853}, doi = {10.1016/j.jmmm.2018.10.066}, pages = {244 -- 248}, year = {2019}, abstract = {The movement of magnetic beads due to a magnetic field gradient is of great interest in different application fields. In this report we present a technique based on a magnetic tweezers setup to measure the velocity factor of magnetically actuated individual superparamagnetic beads in a fluidic environment. Several beads can be tracked simultaneously in order to gain and improve statistics. Furthermore we show our results for different beads with hydrodynamic diameters between 200 and 1000 nm from diverse manufacturers. These measurement data can, for example, be used to determine design parameters for a magnetic separation system, like maximum flow rate and minimum separation time, or to select suitable beads for fixed experimental requirements.}, language = {en} } @inproceedings{SchollBartellaMoluluoetal.2019, author = {Scholl, Ingrid and Bartella, Alex and Moluluo, Cem and Ertural, Berat and Laing, Frederic and Suder, Sebastian}, title = {MedicVR : Acceleration and Enhancement Techniques for Direct Volume Rendering in Virtual Reality}, series = {Bildverarbeitung f{\"u}r die Medizin 2019 : Algorithmen - Systeme - Anwendungen}, booktitle = {Bildverarbeitung f{\"u}r die Medizin 2019 : Algorithmen - Systeme - Anwendungen}, publisher = {Springer Vieweg}, address = {Wiesbaden}, isbn = {978-3-658-25326-4}, doi = {10.1007/978-3-658-25326-4_32}, pages = {152 -- 157}, year = {2019}, language = {en} } @article{SchildtBraunMarzocca2019, author = {Schildt, Ph. and Braun, Carsten and Marzocca, P.}, title = {Metric evaluating potentials of condition-monitoring approaches for hybrid electric aircraft propulsion systems}, series = {CEAS Aeronautical Journal}, journal = {CEAS Aeronautical Journal}, publisher = {Springer}, address = {Berlin}, issn = {1869-5590}, doi = {10.1007/s13272-019-00411-3}, pages = {1 -- 14}, year = {2019}, language = {en} } @article{CampenKowalskiLyonsetal.2019, author = {Campen, R. and Kowalski, Julia and Lyons, W.B. and Tulaczyk, S. and Dachwald, Bernd and Pettit, E. and Welch, K. A. and Mikucki, J.A.}, title = {Microbial diversity of an Antarctic subglacial community and high-resolution replicate sampling inform hydrological connectivity in a polar desert}, series = {Environmental Microbiology}, journal = {Environmental Microbiology}, number = {accepted article}, publisher = {Wiley}, address = {Weinheim}, issn = {1462-2920}, doi = {10.1111/1462-2920.14607}, year = {2019}, language = {en} } @inproceedings{BraunChengLaietal.2019, author = {Braun, Sebastian and Cheng, Chi-Tsun and Lai, Chow Yin and Wollert, J{\"o}rg}, title = {Microservice Architecture for Automation - Realization by the example of a model-factory's manufacturing execution system}, series = {Proceedings of the 23rd World Multi-Conference on Systemics, Cybernetics and Informatics: WMSCI 2019}, booktitle = {Proceedings of the 23rd World Multi-Conference on Systemics, Cybernetics and Informatics: WMSCI 2019}, pages = {33 -- 37}, year = {2019}, language = {en} } @article{JungStaat2019, author = {Jung, Alexander and Staat, Manfred}, title = {Modeling and simulation of human induced pluripotent stem cell-derived cardiac tissue}, series = {GAMM - Mitteilungen der Gesellschaft f{\"u}r Angewandte Mathematik und Mechanik}, volume = {42}, journal = {GAMM - Mitteilungen der Gesellschaft f{\"u}r Angewandte Mathematik und Mechanik}, number = {4}, publisher = {Wiley}, address = {Weinheim}, issn = {1522-2608}, doi = {10.1002/gamm.201900002}, pages = {11 Seiten}, year = {2019}, language = {en} } @article{SlabuRoethEngelmannetal.2019, author = {Slabu, Ioana and Roeth, Anjali A. and Engelmann, Ulrich M. and Wiekhorst, Frank and Buhl, Eva M. and Neumann, Ulf P. and Schmitz-Rode, Thomas}, title = {Modeling of magnetoliposome uptake in human pancreatic tumor cells in vitro}, series = {Nanotechnology}, volume = {30}, journal = {Nanotechnology}, number = {18}, issn = {1361-6528}, doi = {10.1088/1361-6528/ab033e}, pages = {184004}, year = {2019}, language = {en} } @inproceedings{RamanJungHorvathetal.2019, author = {Raman, Aravind Hariharan and Jung, Alexander and Horv{\´a}th, Andr{\´a}s and Becker, Nadine and Staat, Manfred}, title = {Modification of a computer model of human stem cell-derived cardiomyocyte electrophysiology based on Patch-Clamp measurements}, series = {3rd YRA MedTech Symposium 2019 : May 24 / 2019 / FH Aachen}, booktitle = {3rd YRA MedTech Symposium 2019 : May 24 / 2019 / FH Aachen}, editor = {Staat, Manfred and Erni, Daniel}, publisher = {Universit{\"a}t Duisburg-Essen}, address = {Duisburg}, organization = {MedTech Symposium}, isbn = {978-3-940402-22-6}, doi = {10.17185/duepublico/48750}, pages = {10 -- 11}, year = {2019}, abstract = {Human induced pluripotent stem cells (hiPSCs) have shown to be promising in disease studies and drug screenings [1]. Cardiomyocytes derived from hiPSCs have been extensively investigated using patch-clamping and optical methods to compare their electromechanical behaviour relative to fully matured adult cells. Mathematical models can be used for translating findings on hiPSCCMs to adult cells [2] or to better understand the mechanisms of various ion channels when a drug is applied [3,4]. Paci et al. (2013) [3] developed the first model of hiPSC-CMs, which they later refined based on new data [3]. The model is based on iCells® (Fujifilm Cellular Dynamics, Inc. (FCDI), Madison WI, USA) but major differences among several cell lines and even within a single cell line have been found and motivate an approach for creating sample-specific models. We have developed an optimisation algorithm that parameterises the conductances (in S/F=Siemens/Farad) of the latest Paci et al. model (2018) [5] using current-voltage data obtained in individual patch-clamp experiments derived from an automated patch clamp system (Patchliner, Nanion Technologies GmbH, Munich).}, language = {en} } @article{AlbannaLuekeSchubertetal.2019, author = {Albanna, Walid and L{\"u}ke, Jan Niklas and Schubert, Gerrit Alexander and Dibu{\´e}-Adjei, Maxine and Kotliar, Konstantin and Hescheler, J{\"u}rgen and Clusmann, Hans and Steiger, Hans-Jakob and H{\"a}nggi, Daniel and Kamp, Marcel A. and Schneider, Toni and Neumaier, Felix}, title = {Modulation of Ca v 2.3 channels by unconjugated bilirubin (UCB) - Candidate mechanism for UCB-induced neuromodulation and neurotoxicity}, series = {Molecular and Cellular Neuroscience}, volume = {96}, journal = {Molecular and Cellular Neuroscience}, number = {4}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1044-7431}, doi = {10.1016/j.mcn.2019.03.003}, pages = {35 -- 46}, year = {2019}, language = {en} } @inproceedings{MuellerAltherrAholaetal.2019, author = {M{\"u}ller, Tim M. and Altherr, Lena and Ahola, Marja and Schabel, Samuel and Pelz, Peter F.}, title = {Multi-Criteria optimization of pressure screen systems in paper recycling - balancing quality, yield, energy consumption and system complexity}, series = {EngOpt 2018 Proceedings of the 6th International Conference on Engineering Optimization}, booktitle = {EngOpt 2018 Proceedings of the 6th International Conference on Engineering Optimization}, editor = {Rodrigues, H. C.}, publisher = {Springer International Publishing}, address = {Basel}, isbn = {978-3-319-97773-7}, doi = {10.1007/978-3-319-97773-7_105}, year = {2019}, abstract = {The paper industry is the industry with the third highest energy consumption in the European Union. Using recycled paper instead of fresh fibers for papermaking is less energy consuming and saves resources. However, adhesive contaminants in recycled paper are particularly problematic since they reduce the quality of the resulting paper-product. To remove as many contaminants and at the same time obtain as many valuable fibres as possible, fine screening systems, consisting of multiple interconnected pressure screens, are used. Choosing the best configuration is a non-trivial task: The screens can be interconnected in several ways, and suitable screen designs as well as operational parameters have to be selected. Additionally, one has to face conflicting objectives. In this paper, we present an approach for the multi-criteria optimization of pressure screen systems based on Mixed-Integer Nonlinear Programming. We specifically focus on a clear representation of the trade-off between different objectives.}, language = {en} } @article{GoettscheAlexopoulosDuemmleretal.2019, author = {G{\"o}ttsche, Joachim and Alexopoulos, Spiros and D{\"u}mmler, Andreas and Maddineni, S. K.}, title = {Multi-Mirror Array Calculations With Optical Error}, pages = {1 -- 6}, year = {2019}, abstract = {The optical performance of a 2-axis solar concentrator was simulated with the COMSOL Multiphysics® software. The concentrator consists of a mirror array, which was created using the application builder. The mirror facets are preconfigured to form a focal point. During tracking all mirrors are moved simultaneously in a coupled mode by 2 motors in two axes, in order to keep the system in focus with the moving sun. Optical errors on each reflecting surface were implemented in combination with the solar angular cone of ± 4.65 mrad. As a result, the intercept factor of solar radiation that is available to the receiver was calculated as a function of the transversal and longitudinal angles of incidence. In addition, the intensity distribution on the receiver plane was calculated as a function of the incidence angles.}, language = {en} }