@article{SchoeningBronderWuetal.2017, author = {Sch{\"o}ning, Michael Josef and Bronder, Thomas and Wu, Chunsheng and Scheja, Sabrina and Jessing, Max and Metzger-Boddien, Christoph and Keusgen, Michael and Poghossian, Arshak}, title = {Label-Free DNA Detection with Capacitive Field-Effect Devices—Challenges and Opportunities}, series = {Proceedings}, volume = {1}, journal = {Proceedings}, number = {8}, publisher = {MDPI}, address = {Basel}, issn = {2504-3900}, doi = {10.3390/proceedings1080719}, pages = {Artikel 719}, year = {2017}, abstract = {Field-effect EIS (electrolyte-insulator-semiconductor) sensors modified with a positively charged weak polyelectrolyte layer have been applied for the electrical detection of DNA (deoxyribonucleic acid) immobilization and hybridization by the intrinsic molecular charge. The EIS sensors are able to detect the existence of target DNA amplicons in PCR (polymerase chain reaction) samples and thus, can be used as tool for a quick verification of DNA amplification and the successful PCR process. Due to their miniaturized setup, compatibility with advanced micro- and nanotechnologies, and ability to detect biomolecules by their intrinsic molecular charge, those sensors can serve as possible platform for the development of label-free DNA chips. Possible application fields as well as challenges and limitations will be discussed.}, language = {en} } @article{AbouzarPedrazaSchoeningetal.2010, author = {Abouzar, Maryam H. and Pedraza, A. M. and Sch{\"o}ning, Michael Josef and Poghossian, Arshak}, title = {Label-free DNA hybridization and denaturation detection by means of field-effect nanoplate SOI capacitors functionalized with gold nanoparticles}, series = {Procedia Engineering. 5 (2010)}, journal = {Procedia Engineering. 5 (2010)}, isbn = {1877-7058}, pages = {918 -- 921}, year = {2010}, language = {en} } @article{AbouzarPoghossianCherstvyetal.2012, author = {Abouzar, Maryam H. and Poghossian, Arshak and Cherstvy, Andrey G. and Pedraza, Angela M. and Ingebrandt, Sven and Sch{\"o}ning, Michael Josef}, title = {Label-free electrical detection of DNA by means of field-effect nanoplate capacitors: Experiments and modeling}, series = {Physica Status Solidi (a)}, volume = {209}, journal = {Physica Status Solidi (a)}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {1862-6319}, doi = {10.1002/pssa.201100710}, pages = {925 -- 934}, year = {2012}, abstract = {Label-free electrical detection of consecutive deoxyribonucleic acid (DNA) hybridization/denaturation by means of an array of individually addressable field-effect-based nanoplate silicon-on-insulator (SOI) capacitors modified with gold nanoparticles (Au-NP) is investigated. The proposed device detects charge changes on Au-NP/DNA hybrids induced by the hybridization or denaturation event. DNA hybridization was performed in a high ionic-strength solution to provide a high hybridization efficiency. On the other hand, to reduce the screening of the DNA charge by counter ions and to achieve a high sensitivity, the sensor signal induced by the hybridization and denaturation events was measured in a low ionic-strength solution. High sensor signals of about 120, 90, and 80 mV were registered after the DNA hybridization, denaturation, and re-hybridization events, respectively. Fluorescence microscopy has been applied as reference method to verify the DNA immobilization, hybridization, and denaturation processes. An electrostatic charge-plane model for potential changes at the gate surface of a nanoplate field-effect sensor induced by the DNA hybridization has been developed taking into account both the Debye length and the distance of the DNA charge from the gate surface.}, language = {en} } @article{WuBronderPoghossianetal.2014, author = {Wu, Chunsheng and Bronder, Thomas and Poghossian, Arshak and Werner, Frederik and B{\"a}cker, Matthias and Sch{\"o}ning, Michael Josef}, title = {Label-free electrical detection of DNA with a multi-spot LAPS: First step towards light-addressable DNA chips}, series = {Physica status solidi A : Applications and materials science}, volume = {211}, journal = {Physica status solidi A : Applications and materials science}, number = {6}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {1521-396X (E-Journal); 1862-6319 (E-Journal); 0031-8965 (Print); 1862-6300 (Print)}, doi = {10.1002/pssa.201330442}, pages = {1423 -- 1428}, year = {2014}, abstract = {A multi-spot (4 × 4 spots) light-addressable potentiometric sensor (MLAPS) consisting of an Al-p-Si-SiO2 structure has been applied for the label-free electrical detection of DNA (deoxyribonucleic acid) immobilization and hybridization by the intrinsic molecular charge for the first time. Single-stranded probe ssDNA molecules (20 bases) were covalently immobilized onto the silanized SiO2 gate surface. The unspecific adsorption of mismatch ssDNA on the MLAPS gate surface was blocked by bovine serum albumin molecules. To reduce the screening effect and to achieve a high sensor signal, the measurements were performed in a low ionic-strength solution. The photocurrent-voltage (I-V) curves were simultaneously recorded on all 16 spots after each surface functionalization step. Large shifts of I-V curves of 25 mV were registered after the DNA immobilization and hybridization event. In contrast, a small potential shift (∼5 mV) was observed in case of mismatch ssDNA, revealing good specificity of the sensor. The obtained results demonstrate the potential of the MLAPS as promising transducer platform for the multi-spot label-free electrical detection of DNA molecules by their intrinsic molecular charge.}, language = {en} } @inproceedings{PoghossianBronderSchejaetal.2016, author = {Poghossian, Arshak and Bronder, Thomas and Scheja, S. and Wu, Chunsheng and Metzger-Boddien, C. and Keusgen, M. and Sch{\"o}ning, Michael Josef}, title = {Label-free Electrostatic Detection of DNA Amplification by PCR Using Capacitive Field-effect Devices}, series = {Procedia Engineering}, volume = {Vol. 168}, booktitle = {Procedia Engineering}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1877-7058}, doi = {10.1016/j.proeng.2016.11.512}, pages = {514 -- 517}, year = {2016}, abstract = {A capacitive field-effect EIS (electrolyte-insulator-semiconductor) sensor modified with a positively charged weak polyelectrolyte of poly(allylamine hydrochloride) (PAH)/single-stranded probe DNA (ssDNA) bilayer has been used for a label-free electrostatic detection of pathogen-specific DNA amplification via polymerase chain reaction (PCR). The sensor is able to distinguish between positive and negative PCR solutions, to detect the existence of target DNA amplicons in PCR samples and thus, can be used as tool for a quick verification of DNA amplification and the successful PCR process.}, language = {en} } @inproceedings{PoghossianBronderWuetal.2015, author = {Poghossian, Arshak and Bronder, Thomas and Wu, Chunsheng and Sch{\"o}ning, Michael Josef}, title = {Label-free sensing of biomolecules by their intrinsic molecular charge using field-effect devices}, series = {Semiconductor Micro- and Nanoelectonics : Proceedings of the tenth international conference, Yerevan, Armenia, September 11-13}, booktitle = {Semiconductor Micro- and Nanoelectonics : Proceedings of the tenth international conference, Yerevan, Armenia, September 11-13}, isbn = {978-5-8084-1991-9}, pages = {61 -- 63}, year = {2015}, language = {en} } @article{PoghossianSchoening2014, author = {Poghossian, Arshak and Sch{\"o}ning, Michael Josef}, title = {Label-free sensing of biomolecules with field-effect devices for clinical applications}, series = {Electroanalysis}, volume = {26}, journal = {Electroanalysis}, number = {6}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {1521-4109 (E-Journal); 1040-0397 (Print)}, doi = {10.1002/elan.201400073}, pages = {1197 -- 1213}, year = {2014}, abstract = {Among the variety of transducer concepts proposed for label-free detection of biomolecules, the semiconductor field-effect device (FED) is one of the most attractive platforms. As medical techniques continue to progress towards diagnostic and therapies based on biomarkers, the ability of FEDs for a label-free, fast and real-time detection of multiple pathogenic and physiologically relevant molecules with high specificity and sensitivity offers very promising prospects for their application in point-of-care and personalized medicine for an early diagnosis and treatment of diseases. The presented paper reviews recent advances and current trends in research and development of different FEDs for label-free, direct electrical detection of charged biomolecules by their intrinsic molecular charge. The authors are mainly focusing on the detection of the DNA hybridization event, antibody-antigen affinity reaction as well as clinically relevant biomolecules such as cardiac and cancer biomarkers.}, language = {en} } @incollection{Bung2015, author = {Bung, Daniel Bernhard}, title = {Laboratory models of free-surface flows}, series = {Rivers - physical, fluvial and environmental processes}, booktitle = {Rivers - physical, fluvial and environmental processes}, editor = {Rowinski, Pawel}, publisher = {Springer}, address = {Cham}, isbn = {978-3-319-17718-2 ; 978-3-319-17719-9}, doi = {10.1007/978-3-319-17719-9_9}, pages = {213 -- 228}, year = {2015}, abstract = {Hydraulic modeling is the classical approach to investigate and describe complex fluid motion. Many empirical formulas in the literature used for the hydraulic design of river training measures and structures have been developed using experimental data from the laboratory. Although computer capacities have increased to a high level which allows to run complex numerical simulations on standard workstation nowadays, non-standard design of structures may still raise the need to perform physical model investigations. These investigations deliver insight into details of flow patterns and the effect of varying boundary conditions. Data from hydraulic model tests may be used for calibration of numerical models as well. As the field of hydraulic modeling is very complex, this chapter intends to give a short overview on capacities and limits of hydraulic modeling in regard to river flows and hydraulic structures only. The reader shall get a first idea of modeling principles and basic considerations. More detailed information can be found in the references.}, language = {en} } @article{ZischankHeidlerWiesingeretal.2004, author = {Zischank, Wolfgang J. and Heidler, Fridolin and Wiesinger, J. and Metwally, I. and Kern, Alexander and Seevers, M.}, title = {Laboratory simulation of direct lightning strokes to a modeled building : measurement of magnetic fields and included voltages}, series = {Journal of electrostatics. 60 (2004), H. 2 - 4}, journal = {Journal of electrostatics. 60 (2004), H. 2 - 4}, isbn = {0304-3886}, pages = {223 -- 232}, year = {2004}, language = {en} } @inproceedings{ZischankHeidlerKernetal.2002, author = {Zischank, Wolfgang J. and Heidler, Fridolin and Kern, Alexander and Metwally, I. A. and Wiesinger, J. and Seevers, M.}, title = {Laboratory simulation of direct lightning strokes to a modelled building - measurement of magnetic fields and induced voltages}, year = {2002}, abstract = {In IEC 61312-2 equations for the assessment of the magnetic fields inside structures due to a direct lightning strike are given. These equations are based on computer simulations for shields consisting of a single-layer steel grid of a given mesh width. Real constructions, however, contain at least two layers of reinforcement steel grids. The objective of this study was to experimentally determine the additional shielding effectiveness of a second reinforcement layer compared to a single-layer grid. To this end, simulated structures were set up in the high current laboratory. The structures consisted of cubic cages of 2 m side length with one or with two reinforcement grids, respectively. The structures were exposed to direct lightning currents representing the variety of anticipated lightning current waveforms. The magnetic fields and their derivatives at several positions inside the structure as well as the voltage between "floor" and "roof" in the center were determined for different current injection points. From these data the improvement of the shielding caused by a second reinforcement layer is derived.}, language = {en} } @article{SchwarzerWernerHartz2004, author = {Schwarzer, Klemens and Werner, M. and Hartz, T.}, title = {Lacasa - an instrument for the energy analysis and optimisation of buildings including technical equipment}, series = {Proceedings / organised by: ISES Europe ... [Ed.: Deutsche Gesellschaft f{\"u}r Sonnenenergie e.V. - DGS, Munich ; PSE GmbH - Forschung Entwicklung Marketing, Freiburg]. - Vol. 2}, journal = {Proceedings / organised by: ISES Europe ... [Ed.: Deutsche Gesellschaft f{\"u}r Sonnenenergie e.V. - DGS, Munich ; PSE GmbH - Forschung Entwicklung Marketing, Freiburg]. - Vol. 2}, publisher = {PSE}, address = {Freiburg [Breisgau]}, isbn = {3-9809656-2-7}, pages = {2-489-2-494}, year = {2004}, language = {en} } @book{Schwarzer2004, author = {Schwarzer, Klemens}, title = {Lacasa : Einsatz von MATLAB-Simulink zur energetischen Analyse und Optimierung von Alt- und Neubauten inklusive Heizungs-, L{\"u}ftungs- und Klimatechnik / Hrsg.: FIA-Projekt, Forschungs-Informations-Austausch im Fachinstitut Geb{\"a}ude-Klima e.V. Projekt: Solar-Institut J{\"u}lich an der Fachhochschule Aachen}, publisher = {FIA-Projekt im Fachinst. Geb{\"a}ude-Klima}, address = {Bietigheim-Bissingen}, isbn = {3-938210-07-9}, pages = {34 S. : Ill., graph. Darst.}, year = {2004}, language = {en} } @article{Mertens1992, author = {Mertens, Josef}, title = {Laminar flow for supersonic transports}, series = {Proceedings : March 16 - 18, 1992, Congress Centrum, Hamburg, Federal Republic of Germany / organized jointly by: Deutsche Gesellschaft f{\"u}r Luft- und Raumfahrt e.V. ... [Programme committee J. Szodruch ...]}, journal = {Proceedings : March 16 - 18, 1992, Congress Centrum, Hamburg, Federal Republic of Germany / organized jointly by: Deutsche Gesellschaft f{\"u}r Luft- und Raumfahrt e.V. ... [Programme committee J. Szodruch ...]}, publisher = {DGLR}, address = {Bonn}, isbn = {3-922010-73-3}, pages = {319 -- 323}, year = {1992}, language = {en} } @inproceedings{Mertens2000, author = {Mertens, Josef}, title = {Laminar leading edges: manufacturing, contamination, and operational aspects - results from the German RaWid programme}, year = {2000}, abstract = {RaWid was the German national technology programme on transonic aerodynamics and supporting technologies, lasting from 1995 to 1998. One of the main topics was laminar wing development. Besides aerodynamic design work, many operational aspects were investigated. A manufacturing concept was developed to be applied to operational laminar wings and empennages. It was built in a large scale manufacturing demonstrator with the aerodynamic shape of a 1,5 m section of the A320 fin nose. Tolerances in shape and roughness fulfilled all requirements. The construction can easily be adapted to varying stiffness and strength requirements. Weight and manufacturing costs are comparable to common nose designs. The mock-up to be designed in ALTTA is based on this manufacturing principle. Another critical point is contamination of suction surfaces. Several tests were performed to investigate perforated titanium suction surfaces at realistic operational conditions: - a one year flight test with a suction plate in the stagnation area of the Airbus "Beluga" - a one year test of several suction plates in a ground test near the airport - a one year test of a working suction ground test installation at all weather conditions. No critical results were found. There is no long term suction degradation visible. Icing conditions and ground de-icing fluids used on airports did not pose severe problems. Some problems detected require only respection of weak design constraints.}, subject = {Laminare Str{\"o}mung}, language = {en} } @article{WittmannUlamecRichter1999, author = {Wittmann, Klaus and Ulamec, S and Richter, L}, title = {Lander Systems for Planetary Missions}, series = {Laboratory astrophysics and space research / ed. by P. Ehrenfreund}, journal = {Laboratory astrophysics and space research / ed. by P. Ehrenfreund}, publisher = {Kluwer}, address = {Dordrecht [u.a.]}, isbn = {0-7923-5338-2}, pages = {597 -- 621}, year = {1999}, language = {en} } @article{FerreinBeckLakemeyer2009, author = {Ferrein, Alexander and Beck, Daniel and Lakemeyer, Gerhard}, title = {Landmark-Based Representations for Navigating Holonomic Soccer Robots / Beck, Daniel ; Ferrein, Alexander ; Lakemeyer, Gerhard}, series = {RoboCup 2008 : robot soccer world cup XII / Luca Iocchi ... (eds.)}, journal = {RoboCup 2008 : robot soccer world cup XII / Luca Iocchi ... (eds.)}, publisher = {Springer}, address = {Heidelberg}, isbn = {978-3-642-02921-9}, pages = {25 -- 36}, year = {2009}, language = {en} } @article{DantismRoehlenDahmenetal.2020, author = {Dantism, Shahriar and R{\"o}hlen, Desiree and Dahmen, Markus and Wagner, Torsten and Wagner, Patrick and Sch{\"o}ning, Michael Josef}, title = {LAPS-based monitoring of metabolic responses of bacterial cultures in a paper fermentation broth}, series = {Sensors and Actuators B: Chemical}, volume = {320}, journal = {Sensors and Actuators B: Chemical}, number = {Art. 128232}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0925-4005}, doi = {10.1016/j.snb.2020.128232}, year = {2020}, abstract = {As an alternative renewable energy source, methane production in biogas plants is gaining more and more attention. Biomass in a bioreactor contains different types of microorganisms, which should be considered in terms of process-stability control. Metabolically inactive microorganisms within the fermentation process can lead to undesirable, time-consuming and cost-intensive interventions. Hence, monitoring of the cellular metabolism of bacterial populations in a fermentation broth is crucial to improve the biogas production, operation efficiency, and sustainability. In this work, the extracellular acidification of bacteria in a paper-fermentation broth is monitored after glucose uptake, utilizing a differential light-addressable potentiometric sensor (LAPS) system. The LAPS system is loaded with three different model microorganisms (Escherichia coli, Corynebacterium glutamicum, and Lactobacillus brevis) and the effect of the fermentation broth at different process stages on the metabolism of these bacteria is studied. In this way, different signal patterns related to the metabolic response of microorganisms can be identified. By means of calibration curves after glucose uptake, the overall extracellular acidification of bacterial populations within the fermentation process can be evaluated.}, language = {en} } @inproceedings{SeefeldtBauerDachwaldetal.2015, author = {Seefeldt, Patric and Bauer, Waldemar and Dachwald, Bernd and Grundmann, Jan Thimo and Straubel, Marco and Sznajder, Maciej and T{\´o}th, Norbert and Zander, Martin E.}, title = {Large lightweight deployable structures for planetary defence: solar sail propulsion, solar concentrator payloads, large-scale photovoltaic power}, series = {4th IAA Planetary Defense Conference - PDC 2015, 13-17 April 2015, Frascati, Roma, Italy}, booktitle = {4th IAA Planetary Defense Conference - PDC 2015, 13-17 April 2015, Frascati, Roma, Italy}, pages = {24}, year = {2015}, language = {en} } @article{RoesnerScheikOlowinskyetal.2011, author = {Roesner, Andreas and Scheik, Sven and Olowinsky, Alexander and Gillner, Arnold and Reisgen, Uwe and Schleser, Markus}, title = {Laser assisted joining of plastic metal hybrids}, series = {Lasers in manufacturing 2011 : proceedings of the sixth International WLT Conference on Lasers in Manufacturing, Munich, May 23 - 26 2011. (Physics procedia ; Vol. 12 (2011), Part B)}, journal = {Lasers in manufacturing 2011 : proceedings of the sixth International WLT Conference on Lasers in Manufacturing, Munich, May 23 - 26 2011. (Physics procedia ; Vol. 12 (2011), Part B)}, publisher = {Elsevier}, address = {Amsterdam}, organization = {International WLT Conference on Lasers in Manufacturing <6, M{\"u}nchen, 2011>}, issn = {1875-3892 (E-Journal); 1875-3884 (Print)}, pages = {370 -- 377}, year = {2011}, language = {en} } @article{ReisgenOlschokJakobsetal.2012, author = {Reisgen, Uwe and Olschok, Simon and Jakobs, Stefan and Schleser, Markus and Mokrov, Oleg and Rossiter, Eduardo}, title = {Laser beam submerged arc hybrid welding}, series = {Physics procedia}, volume = {39}, journal = {Physics procedia}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1875-3892}, doi = {10.1016/j.phpro.2012.10.016}, pages = {75 -- 83}, year = {2012}, abstract = {The laser beam-submerged arc hybrid welding method originates from the knowledge that, with increasing penetration depth, the laser beam process has a tendency to pore formation in the lower weld regions. The coupling with the energy-efficient submerged-arc process improves degassing and reduces the tendency to pore formation. The high deposition rate of the SA process in combination with the laser beam process offers, providing the appropriate choice of weld preparation, the possibility of welding plates with a thickness larger than 20° mm in a single pass, and also of welding thicker plates with the double-sided single pass technique.}, language = {en} } @article{FerreinStrackLakemeyer2006, author = {Ferrein, Alexander and Strack, Andreas and Lakemeyer, Gerhard}, title = {Laser-Based Localization with Sparse Landmarks / Strack, Andreas ; Ferrein, Alexander ; Lakemeyer, Gerhard}, series = {RoboCup 2005: Robot Soccer World Cup IX}, journal = {RoboCup 2005: Robot Soccer World Cup IX}, publisher = {Springer}, address = {Berlin}, isbn = {978-3-540-35437-6}, pages = {569 -- 576}, year = {2006}, language = {en} } @article{ErmolenkoYoshinobuMourzinaetal.2004, author = {Ermolenko, Y. E. and Yoshinobu, T. and Mourzina, Y. G. and Vlasov, Y. G. and Sch{\"o}ning, Michael Josef and Iwasaki, H.}, title = {Laserscanned transducer (LSST) as a multisensor system}, series = {Sensors and Actuators B. 103 (2004), H. 1-2}, journal = {Sensors and Actuators B. 103 (2004), H. 1-2}, isbn = {0925-4005}, pages = {457 -- 462}, year = {2004}, language = {en} } @article{Gebhardt2001, author = {Gebhardt, Andreas}, title = {Laserwelding with fillerwire}, series = {LIA handbook of laser material processing / Laser Institute of America}, journal = {LIA handbook of laser material processing / Laser Institute of America}, address = {Orlando, Florida}, isbn = {3-540-41770-2}, year = {2001}, language = {en} } @article{MottaghyRath2006, author = {Mottaghy, Darius and Rath, Volker}, title = {Latent heat effects in subsurface heat transport modelling and their impact on palaeotemperature reconstructions}, series = {Geophysical Journal International}, volume = {164}, journal = {Geophysical Journal International}, number = {1}, issn = {1365-246X}, doi = {10.1111/j.1365-246X.2005.02843.x}, pages = {236 -- 245}, year = {2006}, language = {en} } @article{WernerMiyamotoWagneretal.2017, author = {Werner, Frederik and Miyamoto, Ko-ichiro and Wagner, Torsten and Sch{\"o}ning, Michael Josef and Yoshinobu, Tatsuo}, title = {Lateral resolution enhancement of pulse-driven light-addressable potentiometric sensor}, series = {Sensor and Actuators B: Chemical}, volume = {248}, journal = {Sensor and Actuators B: Chemical}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0925-4005}, doi = {10.1016/j.snb.2017.02.057}, pages = {961 -- 965}, year = {2017}, abstract = {To study chemical and biological processes, spatially resolved determination of the concentrations of one or more analyte species is of distinct interest. With a light-addressable potentiometric sensor (LAPS), chemical images can be created, which visualize the concentration distribution above the sensor plate. One important challenge is to achieve a good lateral resolution in order to detect events that take place in a small and limited region. LAPS utilizes a focused light spot to address the measurement region. By moving this light spot along the semiconductor sensor plate, the concentration distribution can be observed. In this study, we show that utilizing a pulse as light excitation instead of a traditionally used continuously modulated light excitation, the lateral resolution can be improved by a factor of 6 or more.}, language = {en} } @article{BialonskiSchindlerElgeretal.2008, author = {Bialonski, Stephan and Schindler, K. and Elger, C. E. and Lehnertz, Klaus}, title = {Lateralized characteristics of the evolution of EEG correlation during focal onset seizures: a mechanism to prevent secondary generalization?}, series = {Epilepsia}, volume = {49}, journal = {Epilepsia}, issn = {0013-9580}, pages = {11 -- 11}, year = {2008}, abstract = {Rationale: Previous studies [Topolnik et al., Cereb Cortex 2003; 13: 883; Schindler et al., Brain 2007; 130: 65] indicate that the termination of focal onset seizures may be causally related to an increase of global neuronal correlation during the second half of the seizures. This increase was observed to occur earlier in complex partial seizures than in secondarily generalized seizures. We here address the question whether such an increase of neuronal correlation prior to seizure end is indeed a global phenomenon, involving both hemispheres or whether there are side-specific differences. Methods: We analyzed 20 focal onset seizures (10 complex partial, 10 secondarily generalized seizures) recorded in 13 patients who underwent presurgical evaluation of focal epilepsies of different origin. EEG was recorded intracranially from bilaterally implanted subdural strip and intrahippocampal depth electrodes. Utilizing a moving window approach, we investigated the evolution of the maximum cross correlation for all channel combinations during seizures. For each moving window the mean value of the maximum cross correlation (MCC) between all electrode contacts was computed separately for each hemisphere. After normalization of seizure durations, MCC values of the ipsi- and contralateral hemisphere for all seizures were determined. Results: We observed that the MCC of the contralateral hemisphere in complex partial seizures increased during the first half of the seizure, whereas, for the same time interval, the MCC of the ipsilateral hemisphere even declined below the level of the pre-seizure period. In contrast, no significant differences between both hemispheres could be observed for secondarily generalized seizures where both hemispheres showed a simultaneous increase of MCC during the second half of the seizures. The level of MCC for the contralateral hemisphere was higher for complex partial seizures than for secondarily generalized seizures during the first half of the seizure. Conclusions: Our findings indicate that there are indeed lateralized differences in the evolution of global neuronal correlation during complex partial and secondarily generalized seizures. The observed contralateral increase of neuronal correlation during complex partial seizures might indicate an emerging self-organizing mechanism for preventing the spread of seizure activity.}, language = {en} } @article{MorandiButenwegBreisetal.2022, author = {Morandi, Paolo and Butenweg, Christoph and Breis, Khaled and Beyer, Katrin and Magenes, Guido}, title = {Latest findings on the behaviour factor q for the seismic design of URM buildings}, series = {Bulletin of Earthquake Engineering}, volume = {20}, journal = {Bulletin of Earthquake Engineering}, number = {11}, editor = {Ansal, Atilla}, publisher = {Springer Nature}, address = {Cham}, issn = {1573-1456}, doi = {10.1007/s10518-022-01419-7}, pages = {5797 -- 5848}, year = {2022}, abstract = {Recent earthquakes as the 2012 Emilia earthquake sequence showed that recently built unreinforced masonry (URM) buildings behaved much better than expected and sustained, despite the maximum PGA values ranged between 0.20-0.30 g, either minor damage or structural damage that is deemed repairable. Especially low-rise residential and commercial masonry buildings with a code-conforming seismic design and detailing behaved in general very well without substantial damages. The low damage grades of modern masonry buildings that was observed during this earthquake series highlighted again that codified design procedures based on linear analysis can be rather conservative. Although advances in simulation tools make nonlinear calculation methods more readily accessible to designers, linear analyses will still be the standard design method for years to come. The present paper aims to improve the linear seismic design method by providing a proper definition of the q-factor of URM buildings. These q-factors are derived for low-rise URM buildings with rigid diaphragms which represent recent construction practise in low to moderate seismic areas of Italy and Germany. The behaviour factor components for deformation and energy dissipation capacity and for overstrength due to the redistribution of forces are derived by means of pushover analyses. Furthermore, considerations on the behaviour factor component due to other sources of overstrength in masonry buildings are presented. As a result of the investigations, rationally based values of the behaviour factor q to be used in linear analyses in the range of 2.0-3.0 are proposed.}, language = {en} } @article{SchererKratzSchaedeletal.1988, author = {Scherer, Ulrich W. and Kratz, J. V. and Sch{\"a}del, M. and Br{\"u}chle, W.}, title = {Lawrencium Chemistry: No Evidence for Oxidation States Lower than 3+ in Aqueous Solution / U.W. Scherer, J.V. Kratz, M. Sch{\"a}del, W. Br{\"u}chle, K.E. Gregorich, R.A. Henderson, D. Lee, M. Nurmia, D.C. Hoffman}, series = {Inorganica Chimica Acta. 146 (1988)}, journal = {Inorganica Chimica Acta. 146 (1988)}, isbn = {0020-1693}, pages = {249 -- 254}, year = {1988}, language = {en} } @article{Foerster2003, author = {F{\"o}rster, Arnold}, title = {Layer Deposition I}, series = {Fundamentals of nanoelectronics / Stefan Bl{\"u}gel ... (ed.). - (Lecture manuscripts of the ... Spring School of the Department of Solid State Research ; 34). - (Schriften des Forschungszentrums J{\"u}lich : Materie und Material ; 14 ; 34)}, journal = {Fundamentals of nanoelectronics / Stefan Bl{\"u}gel ... (ed.). - (Lecture manuscripts of the ... Spring School of the Department of Solid State Research ; 34). - (Schriften des Forschungszentrums J{\"u}lich : Materie und Material ; 14 ; 34)}, publisher = {Forschungszentrum, Zentralbibliothek}, address = {J{\"u}lich}, isbn = {3-89336-319-X}, pages = {C2.1 -- C2.13}, year = {2003}, language = {en} } @article{SiqueiraWernerBaeckeretal.2009, author = {Siqueira, Jose R. and Werner, Frederik and B{\"a}cker, Matthias and Poghossian, Arshak and Zucolotto, Valtencir and Oliveira, Osvaldo N. Jr. and Sch{\"o}ning, Michael Josef}, title = {Layer-by-Layer Assembly of Carbon Nanotubes Incorporated in Light-Addressable Potentiometric Sensors}, series = {Journal of Physical Chemistry C. 113 (2009), H. 33}, journal = {Journal of Physical Chemistry C. 113 (2009), H. 33}, publisher = {American Chemical Society}, address = {Washington, DC}, isbn = {1932-7455}, pages = {14765 -- 14770}, year = {2009}, language = {en} } @article{MoraisSumanSchoeningetal.2023, author = {Morais, Paulo V. and Suman, Pedro H. and Sch{\"o}ning, Michael Josef and Siqueira Junior, Jos{\´e} R. and Orlandi, Marcelo O.}, title = {Layer-by-layer film based on Sn₃O₄ nanobelts as sensing units to detect heavy metals using a capacitive field-effect sensor platform}, series = {Chemosensors}, volume = {11}, journal = {Chemosensors}, number = {8}, publisher = {MDPI}, address = {Basel}, issn = {2227-9040}, doi = {10.3390/chemosensors11080436}, pages = {Artikel 436}, year = {2023}, abstract = {Lead and nickel, as heavy metals, are still used in industrial processes, and are classified as "environmental health hazards" due to their toxicity and polluting potential. The detection of heavy metals can prevent environmental pollution at toxic levels that are critical to human health. In this sense, the electrolyte-insulator-semiconductor (EIS) field-effect sensor is an attractive sensing platform concerning the fabrication of reusable and robust sensors to detect such substances. This study is aimed to fabricate a sensing unit on an EIS device based on Sn₃O₄ nanobelts embedded in a polyelectrolyte matrix of polyvinylpyrrolidone (PVP) and polyacrylic acid (PAA) using the layer-by-layer (LbL) technique. The EIS-Sn₃O₄ sensor exhibited enhanced electrochemical performance for detecting Pb²⁺ and Ni²⁺ ions, revealing a higher affinity for Pb²⁺ ions, with sensitivities of ca. 25.8 mV/decade and 2.4 mV/decade, respectively. Such results indicate that Sn₃O₄ nanobelts can contemplate a feasible proof-of-concept capacitive field-effect sensor for heavy metal detection, envisaging other future studies focusing on environmental monitoring.}, language = {en} } @article{BhattaraiMayStaatetal.2022, author = {Bhattarai, Aroj and May, Charlotte Anabell and Staat, Manfred and Kowalczyk, Wojciech and Tran, Thanh Ngoc}, title = {Layer-specific damage modeling of porcine large intestine under biaxial tension}, series = {Bioengineering}, volume = {9}, journal = {Bioengineering}, number = {10, Early Access}, publisher = {MDPI}, address = {Basel}, issn = {2306-5354}, doi = {10.3390/bioengineering9100528}, pages = {1 -- 17}, year = {2022}, abstract = {The mechanical behavior of the large intestine beyond the ultimate stress has never been investigated. Stretching beyond the ultimate stress may drastically impair the tissue microstructure, which consequently weakens its healthy state functions of absorption, temporary storage, and transportation for defecation. Due to closely similar microstructure and function with humans, biaxial tensile experiments on the porcine large intestine have been performed in this study. In this paper, we report hyperelastic characterization of the large intestine based on experiments in 102 specimens. We also report the theoretical analysis of the experimental results, including an exponential damage evolution function. The fracture energies and the threshold stresses are set as damage material parameters for the longitudinal muscular, the circumferential muscular and the submucosal collagenous layers. A biaxial tensile simulation of a linear brick element has been performed to validate the applicability of the estimated material parameters. The model successfully simulates the biomechanical response of the large intestine under physiological and non-physiological loads.}, language = {en} } @article{StarkeDrews1994, author = {Starke, G{\"u}nther and Drews, P.}, title = {Le soudage au siecle de l'informatique}, series = {Souder. 18 (1994), H. 6}, journal = {Souder. 18 (1994), H. 6}, isbn = {0246-1900}, pages = {33 -- 44}, year = {1994}, language = {en} } @inproceedings{Wessling2007, author = {Weßling, Matthias}, title = {Leadership Perspectives: Research Findings, Theories, Practical Experiences}, year = {2007}, abstract = {Leadership Perspectives: Research Findings, Theories, Practical Experiences: Results of Leadership Research and exemplarily application cases show the perspectives and consequences for leadership practice and the following requirements for executives in future.}, subject = {Leadership}, language = {en} } @article{MuellerVeggianDeNardoBalbinotetal.2005, author = {M{\"u}ller-Veggian, Mattea and De Nardo, L. and Balbinot, G. and Colautti, P.}, title = {Leak Microstructures Operation at low pressure of propane: application at the Trigger\&Anti-Trigger system of the STARTRACK Experiment}, series = {Annual report / Istituto Nazionale di Fisica Nucleare, LNL, Laboratori Nazionali di Legnaro. 2004 (2005)}, journal = {Annual report / Istituto Nazionale di Fisica Nucleare, LNL, Laboratori Nazionali di Legnaro. 2004 (2005)}, isbn = {88-7337-008-X}, pages = {242 -- 243}, year = {2005}, language = {en} } @inproceedings{WiesenEngemannLimpertetal.2018, author = {Wiesen, Patrick and Engemann, Heiko and Limpert, Nicolas and Kallweit, Stephan}, title = {Learning by Doing - Mobile Robotics in the FH Aachen ROS Summer School}, series = {European Robotics Forum 2018, TRROS18 Workshop}, booktitle = {European Robotics Forum 2018, TRROS18 Workshop}, pages = {47 -- 58}, year = {2018}, language = {en} } @article{FerreinKonurLakemeyer2004, author = {Ferrein, Alexander and Konur, Savas and Lakemeyer, Gerhard}, title = {Learning Decision Trees for Action Selection in Soccer Agents / Konur, Savas ; Ferrein, Alexander ; Lakemeyer, Gerhard}, pages = {1 -- 7}, year = {2004}, language = {en} } @article{Fabo2002, author = {Fabo, Sabine}, title = {Learning from Brachelen}, series = {Freistil (Boxhorn ; 8)}, journal = {Freistil (Boxhorn ; 8)}, publisher = {FH Aachen, Fachbereich Gestaltung}, address = {Aachen}, pages = {2,1 -- 2,31}, year = {2002}, language = {en} } @inproceedings{FerreinKallweitScholletal.2015, author = {Ferrein, Alexander and Kallweit, Stephan and Scholl, Ingrid and Reichert, Walter}, title = {Learning to Program Mobile Robots in the ROS Summer School Series}, series = {Proceedings 6th International Conference on Robotics in Education (RiE 15)}, booktitle = {Proceedings 6th International Conference on Robotics in Education (RiE 15)}, pages = {6 S.}, year = {2015}, abstract = {The main objective of our ROS Summer School series is to introduce MA level students to program mobile robots with the Robot Operating System (ROS). ROS is a robot middleware that is used my many research institutions world-wide. Therefore, many state-of-the-art algorithms of mobile robotics are available in ROS and can be deployed very easily. As a basic robot platform we deploy a 1/10 RC cart that is wquipped with an Arduino micro-controller to control the servo motors, and an embedded PC that runs ROS. In two weeks, participants get to learn the basics of mobile robotics hands-on. We describe our teaching concepts and our curriculum and report on the learning success of our students.}, language = {en} } @misc{Kaemper2007, author = {K{\"a}mper, Klaus-Peter}, title = {Lecture notes Sensors and Actuators}, year = {2007}, abstract = {Kennwortgesch{\"u}tzter Zugang nur f{\"u}r Studierende bei Prof. Dr. Klaus-Peter K{\"a}mper. Wintersemester 2007/2008. Version vom 30.08.2007. 472 Seiten (pdf-Format)}, subject = {Sensor}, language = {en} } @misc{Kaemper2008, author = {K{\"a}mper, Klaus-Peter}, title = {Lecture notes Sensors and Actuators WS 2008/2009}, year = {2008}, abstract = {Password necessarily. Access only for Students by Prof. Dr. Klaus-Peter K{\"a}mper. Winter semester 2008/2009. 488 pages (pdf) Contents 1. Introduction 2. Introduction to Sensors 3. Introduction to Microfabrication 4. Pressure Sensors 5. Acceleration Sensors 6. Angular Rate Sensors 7. Position Sensors 8. Flow Sensors 9. Piezoelectric Actuators 10. Magnetostrictive Actuators 11. Actuators based on Shape Memory Alloys 12. Actuators based on Electrorheological Fluids 13. Actuators based on Magnetorheological Fluids 14. Index}, subject = {Sensor}, language = {en} } @article{BlomeKundt1988, author = {Blome, Hans-Joachim and Kundt, Wolfgang}, title = {Leptonic jets from young stellar objects?}, series = {Astrophysics and Space Science. 148 (1988), H. 2}, journal = {Astrophysics and Space Science. 148 (1988), H. 2}, isbn = {0004-640X}, pages = {343 -- 361}, year = {1988}, language = {en} } @inproceedings{BoernerFunkeHendricketal.2009, author = {B{\"o}rner, Sebastian and Funke, Harald and Hendrick, P. and Recker, E.}, title = {LES of Jets In Cross-Flow and Application to the "Micromix" Hydrogen Combustion}, series = {XIX International Symposium on Air Breathing Engines 2009 (ISABE 2009) : Proceedings of a meeting held 7-11 September 2009, Montreal, Canada}, booktitle = {XIX International Symposium on Air Breathing Engines 2009 (ISABE 2009) : Proceedings of a meeting held 7-11 September 2009, Montreal, Canada}, isbn = {9781615676064}, pages = {1555 -- 1561}, year = {2009}, language = {en} } @misc{FrauenrathPfeifferHezeletal.2012, author = {Frauenrath, Tobias and Pfeiffer, Harald and Hezel, Fabian and Dieringer, Matthias A. and Winter, Lukas and Gr{\"a}ßl, Andreas and Santoro, Davide and {\"O}zerdem, Celal and Renz, Wolfgang and Greiser, Andreas and Niendorf, Thoralf}, title = {Lessons learned from cardiac MRI at 7.0 T: LV function assessment at 3.0 T using local multi-channel transceiver coil arrays}, series = {2012 ISMRM Annual Meeting Proceedings}, journal = {2012 ISMRM Annual Meeting Proceedings}, issn = {1545-4428}, year = {2012}, abstract = {Cardiac MR (CMR) is of proven clinical value but also an area of vigorous ongoing research since image quality is not always exclusively defined by signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR). Recent developments of CMR at 7.0 T have been driven by pioneering explorations into novel multichannel transmit and receive coil array technology to tackle the challenges B1+-field inhomogeneities, to offset specific-absorption rate (SAR) constraints and to reduce banding artifacts in SSFP imaging. For this study, recognition of the benefits and performance of local surface Tx/Rx-array structures recently established at 7.0 T inspired migration to 3.0 T, where RF inhomogeneities and SAR limitations encountered in routine clinical CMR, though somewhat reduced versus the 7.0 T situation, remain significant. For all these reasons, this study was designed to build and examine the feasibility of a local four channel Tx/Rx cardiac coil array for anatomical and functional cardiac imaging at 3.0 T. For comparison, a homebuilt 4 channel Rx cardiac coil array exhibiting the same geometry as the Tx/Rx coil and a Rx surface coil array were used.}, language = {en} } @inproceedings{FerreinNiemuellerSchifferetal.2013, author = {Ferrein, Alexander and Niem{\"u}ller, Tim and Schiffer, Stefan and Lakemeyer, Gerhard}, title = {Lessons learnt from developing the embodied AI platform CAESAR for domestic service robotics}, series = {Designing intelligent robots : reintegrating AI II ; papers from the AAAI spring symposium ; [held March 25 - 27, 2013 in Palo Alto, California, USA, on the campus of Stanford University]. (Technical Report / Association for the Advancement of Artificial Intelligence ; 2013,4)}, booktitle = {Designing intelligent robots : reintegrating AI II ; papers from the AAAI spring symposium ; [held March 25 - 27, 2013 in Palo Alto, California, USA, on the campus of Stanford University]. (Technical Report / Association for the Advancement of Artificial Intelligence ; 2013,4)}, editor = {Boots, Byron}, organization = {American Association for Artificial Intelligence}, isbn = {9781577356011}, pages = {21 -- 26}, year = {2013}, language = {en} } @article{TemizArtmannBaskurtPekcetinetal.2000, author = {Temiz Artmann, Ayseg{\"u}l and Baskurt, Oguz K. and Pekcetin, C. and Kandemir, F.}, title = {Leukocyte activation, oxidant stress and red blood cell properties after acute, exhausting exercise in rats. Temiz, A.; Baskurt, O. K., Pekcetin, C.; Kandemir, F.; G{\"u}re, A.}, series = {Clinical Hemorheology and Microcirculation. 22 (2000), H. 4}, journal = {Clinical Hemorheology and Microcirculation. 22 (2000), H. 4}, isbn = {1386-0291}, pages = {253 -- 259}, year = {2000}, language = {en} } @article{MuellerVeggianTarasDehnhardtetal.1972, author = {M{\"u}ller-Veggian, Mattea and Taras, P. and Dehnhardt, W. and Mills, S. J.}, title = {Level properties in the even even nuclei ¹³⁰,¹³²,¹³⁴ Ce - further evidence for the back bending effect}, series = {Conf{\´e}rence europ{\´e}enne de physique nucl{\´e}aire : Aix-en-Provence, 26 juin - 1. juillet 1972 ; comptes rendus des communication = European conference on nuclear physics / patronn{\´e}e par La Soci{\´e}t{\´e} Fran{\c{c}}aise de Physique et La Soci{\´e}t{\´e} Europ{\´e}enne de Physique. Publ. avec le concours de Madeleine Porneuf}, journal = {Conf{\´e}rence europ{\´e}enne de physique nucl{\´e}aire : Aix-en-Provence, 26 juin - 1. juillet 1972 ; comptes rendus des communication = European conference on nuclear physics / patronn{\´e}e par La Soci{\´e}t{\´e} Fran{\c{c}}aise de Physique et La Soci{\´e}t{\´e} Europ{\´e}enne de Physique. Publ. avec le concours de Madeleine Porneuf}, address = {[Paris]}, pages = {102}, year = {1972}, language = {en} } @article{HoylerBalodisProkofjevs1998, author = {Hoyler, Friedrich and Balodis, M. and Prokofjevs, P.}, title = {Level scheme of 194Ir / M. Balodis ; P. Prokofjevs ... F. Hoyler ...}, series = {Nuclear physics / A. 641 (1998), H. 2}, journal = {Nuclear physics / A. 641 (1998), H. 2}, isbn = {0375-9474}, pages = {133 -- 187}, year = {1998}, language = {en} } @article{MuellerVeggianGonoLieder1978, author = {M{\"u}ller-Veggian, Mattea and Gono, Y. and Lieder, R. M.}, title = {Level structure in the light transitional nuclei ¹³⁶,¹³⁷,¹³⁸ Ce}, series = {Proceedings of the International Conference on Nuclear Structure : Tokyo, Sept. 5 - 10, 1977 / ed. by T. Marumori. - Journal of the Physical Society of Japan ; Vol. 44, 1978 : Suppl.}, journal = {Proceedings of the International Conference on Nuclear Structure : Tokyo, Sept. 5 - 10, 1977 / ed. by T. Marumori. - Journal of the Physical Society of Japan ; Vol. 44, 1978 : Suppl.}, publisher = {Physical Soc. of Japan}, address = {Tokyo}, pages = {862}, year = {1978}, language = {en} } @inproceedings{MuellerVeggianDehnhardtMills1975, author = {M{\"u}ller-Veggian, Mattea and Dehnhardt, W. and Mills, J. S.}, title = {Levels in the closed neutron shell nucleus ¹⁴² Nd}, series = {International Symposium on Highly Excited States in Nuclei held at J{\"u}lich from 23-26 September 1975 : proceedings; Vol. 1 Contributed papers}, booktitle = {International Symposium on Highly Excited States in Nuclei held at J{\"u}lich from 23-26 September 1975 : proceedings; Vol. 1 Contributed papers}, publisher = {Verlag des Forschungszentrums J{\"u}lich}, address = {J{\"u}lich}, pages = {51}, year = {1975}, language = {en} }