@article{KotliarKoshitzSvetlowaetal.2005,
  author    = {Kotliar, Konstantin and Koshitz, I. N. and Svetlowa, O. V. and Makarov, F. N.},
  title     = {Biomechanical analysis of traditional and contemporary conceptions on pathogenesis of the primary open angle glaucoma / Koshitz, I. N. ; Svetlova, O. V. ; Kotliar, K. E. ; Makarov, F. N. ; Smolnikov, B. A.},
  series = {Glaukoma (2005)},
  journal   = {Glaukoma (2005)},
  publisher = {-},
  pages     = {41 -- 63},
  year      = {2005},
  language  = {en}
}
@book{ArtmannTemizArtmannZhubanovaetal.2018,
  author    = {Artmann, Gerhard and Temiz Artmann, Ayseg{\"u}l and Zhubanova, Azhar A. and Digel, Ilya},
  title     = {Biological, physical and technical basics of cell engineering},
  editor    = {Artmann, Gerhard and Temiz Artmann, Ayseg{\"u}l and Zhubanova, Azhar A. and Digel, Ilya},
  publisher = {Springer},
  address   = {Singapore},
  isbn      = {978-981-10-7903-0},
  pages     = {xxiv, 481 Seiten ; Illustrationen, Diagramme},
  year      = {2018},
  language  = {en}
}
@article{SchoeningPoghossian2006,
  author    = {Sch{\"o}ning, Michael Josef and Poghossian, Arshak},
  title     = {BioFEDs (field-effect devices) : State-of-the-art and new directions},
  series = {Electroanalysis},
  volume    = {18},
  journal   = {Electroanalysis},
  number    = {19-20},
  issn      = {1521-4109},
  doi       = {10.1002/elan.200603609},
  pages     = {1893 -- 1900},
  year      = {2006},
  language  = {en}
}
@book{Artmann2008,
  author    = {Artmann, Gerhard},
  title     = {Bioengineering in Cell and Tissue Research / Artmann, Gerhard M. ; Chien, Shu (Eds.)},
  publisher = {Springer},
  address   = {Berlin},
  isbn      = {978-3-540-75408-4},
  year      = {2008},
  language  = {en}
}
@article{SchrothWeissbeckerSchuetzetal.2002,
  author    = {Schroth, P. and Weißbecker, B. and Sch{\"u}tz, S. and Ecken, H. and Yoshinobu, T. and L{\"u}th, H. and Sch{\"o}ning, Michael Josef},
  title     = {Bioelectronic signal processing - intact chemoreceptors coupled to field-effect devices},
  series = {Lecture Notes of the ICB Seminars},
  journal   = {Lecture Notes of the ICB Seminars},
  publisher = {MCB},
  address   = {Warsaw},
  pages     = {28 -- 42},
  year      = {2002},
  language  = {en}
}
@article{SchrothWeissbeckerSchuetzetal.2001,
  author    = {Schroth, P. and Weißbecker, B. and Sch{\"u}tz, S. and Ecken, H. and Yoshinobu, T. and L{\"u}th, H. and Sch{\"o}ning, Michael Josef},
  title     = {Bioelectronic signal processing - intact chemoreceptors coupled to field-effect devices},
  series = {Biocybernetics and Biomedical Engineering. 21 (2001), H. 3},
  journal   = {Biocybernetics and Biomedical Engineering. 21 (2001), H. 3},
  isbn      = {0208-5216},
  pages     = {27 -- 42},
  year      = {2001},
  language  = {en}
}
@incollection{MansurovJandosovChenchiketal.2020,
  author    = {Mansurov, Zulkhair A. and Jandosov, Jakpar and Chenchik, D. and Azat, Seitkhan and Savitskaya, Irina S. and Kistaubaeva, Aida and Akimbekov, Nuraly S. and Digel, Ilya and Zhubanova, Azhar Achmet},
  title     = {Biocomposite Materials Based on Carbonized Rice Husk in Biomedicine and Environmental Applications},
  series = {Carbon Nanomaterials in Biomedicine and the Environment},
  booktitle = {Carbon Nanomaterials in Biomedicine and the Environment},
  publisher = {Jenny Stanford Publishing Pte. Ltd.},
  address   = {Singapore},
  isbn      = {978-981-4800-27-3},
  doi       = {10.1201/9780429428647-2},
  pages     = {3 -- 32},
  year      = {2020},
  abstract  = {This chapter describes the prospects for biomedical and environmental engineering applications of heterogeneous materials based on nanostructured carbonized rice husk. Efforts in engineering enzymology are focused on the following directions: development and optimization of immobilization methods leading to novel biotechnological and biomedical applications; construction of biocomposite materials based on individual enzymes, multi-enzyme complexes and whole cells, targeted on realization of specific industrial processes. Molecular biological and biochemical studies on cell adhesion focus predominantly on identification, isolation and structural analysis of attachment-responsible biological molecules and their genetic determinants. The chapter provides a short overview of applications of the biocomposite materials based of nanostructured carbonized adsorbents. It emphasizes that further studies and better understanding of the interactions between CNS and microbial cells are necessary. The future use of living cells as biocatalysts, especially in the environmental field, needs more systematic investigations of the microbial adsorption phenomenon.},
  language  = {en}
}
@article{AkimbekovDigelTastambeketal.2013,
  author    = {Akimbekov, Nuraly S. and Digel, Ilya and Tastambek, K. T. and Zhubanova, A. A.},
  title     = {Biocompatibility of carbonized rice husk with a rat heart cells line H9c2},
  series = {Experimental Biology},
  volume    = {59},
  journal   = {Experimental Biology},
  number    = {3/1},
  issn      = {1563-0218},
  pages     = {23 -- 25},
  year      = {2013},
  language  = {en}
}
@article{LuethThustSteffenetal.2000,
  author    = {L{\"u}th, H. and Thust, M. and Steffen, A. and Kordos, P. and Sch{\"o}ning, Michael Josef},
  title     = {Biochemical sensors with structured and porous silicon capacitors},
  series = {Materials Science and Engineering B. 69-70 (2000)},
  journal   = {Materials Science and Engineering B. 69-70 (2000)},
  isbn      = {0921-5107},
  pages     = {104 -- 108},
  year      = {2000},
  language  = {en}
}
@article{KramerHalamkovaPoghossianetal.2013,
  author    = {Kramer, Friederike and Halamkova, Lenka and Poghossian, Arshak and Sch{\"o}ning, Michael Josef and Katz, Evgeny and Halamek, Jan},
  title     = {Biocatalytic analysis of biomarkers for forensic identification of ethnicity between Caucasian and African American},
  series = {The analyst. August 2013},
  volume    = {Vol. 138},
  journal   = {The analyst. August 2013},
  publisher = {Royal Society of Chemistry},
  address   = {Cambridge},
  issn      = {1364-5528 (E-Journal); 0003-2654 (Print)},
  pages     = {6251 -- 6257},
  year      = {2013},
  language  = {en}
}
@article{UysalCreutzFiratetal.2022,
  author    = {Uysal, Karya and Creutz, Till and Firat, Ipek Seda and Artmann, Gerhard and Teusch, Nicole and Temiz Artmann, Ayseg{\"u}l},
  title     = {Bio-functionalized ultra-thin, large-area and waterproof silicone membranes for biomechanical cellular loading and compliance experiments},
  series = {Polymers},
  volume    = {14},
  journal   = {Polymers},
  number    = {11},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {2073-4360},
  pages     = {2213},
  year      = {2022},
  abstract  = {Biocompatibility, flexibility and durability make polydimethylsiloxane (PDMS) membranes top candidates in biomedical applications. CellDrum technology uses large area, <10 µm thin membranes as mechanical stress sensors of thin cell layers. For this to be successful, the properties (thickness, temperature, dust, wrinkles, etc.) must be precisely controlled. The following parameters of membrane fabrication by means of the Floating-on-Water (FoW) method were investigated: (1) PDMS volume, (2) ambient temperature, (3) membrane deflection and (4) membrane mechanical compliance. Significant differences were found between all PDMS volumes and thicknesses tested (p < 0.01). They also differed from the calculated values. At room temperatures between 22 and 26 °C, significant differences in average thickness values were found, as well as a continuous decrease in thicknesses within a 4 °C temperature elevation. No correlation was found between the membrane thickness groups (between 3-4 µm) in terms of deflection and compliance. We successfully present a fabrication method for thin bio-functionalized membranes in conjunction with a four-step quality management system. The results highlight the importance of tight regulation of production parameters through quality control. The use of membranes described here could also become the basis for material testing on thin, viscous layers such as polymers, dyes and adhesives, which goes far beyond biological applications.},
  language  = {en}
}
@article{MansurovDigelBiisenbaevetal.2012,
  author    = {Mansurov, Z. and Digel, Ilya and Biisenbaev, M. and Savistkaya, I. and Kistaubaeva, A. and Akimbekov, Nuraly S. and Zhubanova, A.},
  title     = {Bio-composite material on the basis of carbonized rice husk in biomedicine and environmental applications},
  series = {Eurasian Chemico-Technological Journal},
  volume    = {14},
  journal   = {Eurasian Chemico-Technological Journal},
  number    = {2},
  publisher = {Institute of Combustion Problems},
  address   = {Almaty},
  issn      = {2522-4867},
  doi       = {10.18321/ectj105},
  pages     = {115 -- 131},
  year      = {2012},
  language  = {en}
}
@article{ZiemonsBruyndonckxPerezetal.2008,
  author    = {Ziemons, Karl and Bruyndonckx, P. and Perez, J. M. and Pietrzyk, U. and Rato, P. and Tavernier, S.},
  title     = {Beyond ClearPET: Next Aims},
  series = {5th IEEE International Symposium on Biomedical Imaging: From Nano to Macro Symposium Proceedings ISBI 2008},
  journal   = {5th IEEE International Symposium on Biomedical Imaging: From Nano to Macro Symposium Proceedings ISBI 2008},
  isbn      = {978-1-4244-2003-2},
  pages     = {1421 -- 1424},
  year      = {2008},
  abstract  = {The CRYSTAL CLEAR collaboration, in short CCC, is a consortium of 12 academic institutions, mainly from Europe, joining efforts in the area of developing instrumentation for nuclear medicine and medical imaging. In the framework of the CCC a high performance small animal PET system, called ClearPET, was developed by using new technologies in electronics and crystals in a phoswich arrangement combining two types of lutetium- based scintillator materials: LSO:Ce and LuYAP:Ce. Our next aim will be the development of hybrid image systems. Hybrid MR-PET imaging has many unique advantages for brain research. This has sparked a new research line within CCC for the development of novel MR-PET compatible technologies. MRI is not as sensitive as PET but PET has poorer spatial resolution than MRI. Two major advantages of PET are sensitivity and its ability to acquire metabolic information. To assess these innovations, the development of a 9.4T hybrid animal MR-PET scanner is proposed based on an existing 9.4T MR scanner that will be adapted to enable simultaneous acquisition of MR and PET data using cutting- edge technology for both MR and PET.},
  language  = {en}
}
@article{BuniatyanHuckPoghossianetal.2013,
  author    = {Buniatyan, V. and Huck, Christina and Poghossian, Arshak and Aroutiounian, V. M. and Sch{\"o}ning, Michael Josef},
  title     = {BaxSr1-x TiO3/pc-Si heterojunction capacitance},
  series = {Armenian journal of physics},
  volume    = {6},
  journal   = {Armenian journal of physics},
  number    = {4},
  publisher = {National Academy of Sciences of Armenia},
  address   = {Yerevan},
  issn      = {1829-1171},
  pages     = {188 -- 197},
  year      = {2013},
  language  = {en}
}
@article{BuniatyanHuckPoghossianetal.2013,
  author    = {Buniatyan, V. and Huck, Christina and Poghossian, Arshak and Aroutiounian, V. M. and Sch{\"o}ning, Michael Josef},
  title     = {BaxSr1-x TiO3/pc-Si heterojunction},
  series = {Armenian journal of physics},
  volume    = {6},
  journal   = {Armenian journal of physics},
  number    = {4},
  publisher = {National Academy of Sciences of Armenia},
  address   = {Yerevan},
  issn      = {1829-1171},
  pages     = {177 -- 187},
  year      = {2013},
  language  = {en}
}
@incollection{StaatHeitzer2003,
  author    = {Staat, Manfred and Heitzer, M.},
  title     = {Basis reduction technique for limit and shakedown problems},
  series = {Numerical Methods for Limit and Shakedown Analysis. Deterministic and Probabilistic Approach. NIC Series Vol. 15 / Ed. by Staat, M.; Heitzer, M.},
  booktitle = {Numerical Methods for Limit and Shakedown Analysis. Deterministic and Probabilistic Approach. NIC Series Vol. 15 / Ed. by Staat, M.; Heitzer, M.},
  publisher = {John von Neumann Institute for Computing (NIC)},
  address   = {J{\"u}lich},
  isbn      = {3-00-010001-6},
  url       = {http://nbn-resolving.de/urn:nbn:de:0001-2018112115},
  pages     = {1 -- 55},
  year      = {2003},
  language  = {en}
}
@article{Staat2000,
  author    = {Staat, Manfred},
  title     = {Basis Reduction for the Shakedown Problem for Bounded Kinematic Hardening Material},
  year      = {2000},
  abstract  = {Limit and shakedown analysis are effective methods for assessing the load carrying capacity of a given structure. The elasto-plastic behavior of the structure subjected to loads varying in a given load domain is characterized by the shakedown load factor, defined as the maximum factor which satisfies the sufficient conditions stated in the corresponding static shakedown theorem. The finite element dicretization of the problem may lead to very large convex optimization. For the effective solution a basis reduction method has been developed that makes use of the special problem structure for perfectly plastic material. The paper proposes a modified basis reduction method for direct application to the two-surface plasticity model of bounded kinematic hardening material. The considered numerical examples show an enlargement of the load carrying capacity due to bounded hardening.},
  subject      = {Finite-Elemente-Methode},
  language  = {en}
}
@article{MuellerVeggianNeskakisBeuscheretal.1979,
  author    = {M{\"u}ller-Veggian, Mattea and Neskakis, A. and Beuscher, H. and Haenni, D. R.},
  title     = {Band structure in ¹⁹⁴ Au},
  series = {Annual report 1978 / Kernforschungsanlage J{\"u}lich Institut f{\"u}r Kernphysik / Hrsg.: A. F{\"a}ssler. - (Spezielle Berichte der Kernforschungsanlage J{\"u}lich ; 36)},
  journal   = {Annual report 1978 / Kernforschungsanlage J{\"u}lich Institut f{\"u}r Kernphysik / Hrsg.: A. F{\"a}ssler. - (Spezielle Berichte der Kernforschungsanlage J{\"u}lich ; 36)},
  publisher = {Kernforschungsanlage},
  address   = {J{\"u}lich},
  pages     = {36},
  year      = {1979},
  language  = {en}
}
@article{MuellerVeggianBeuscherNeskakisetal.1978,
  author    = {M{\"u}ller-Veggian, Mattea and Beuscher, H. and Neskakis, A and Gono, Y.},
  title     = {Band structure in ¹⁹⁰,¹⁹² Au},
  series = {Annual report 1977 / Institut f{\"u}r Kernphysik Kernforschungsanlage J{\"u}lich},
  journal   = {Annual report 1977 / Institut f{\"u}r Kernphysik Kernforschungsanlage J{\"u}lich},
  publisher = {Verlag des Forschungszentrums J{\"u}lich},
  address   = {J{\"u}lich},
  pages     = {46 -- 47},
  year      = {1978},
  language  = {en}
}
@article{MuellerVeggianBeuscherNeskakisetal.1978,
  author    = {M{\"u}ller-Veggian, Mattea and Beuscher, H. and Neskakis, A and Gono, Y.},
  title     = {Band structure in ¹⁹⁰,¹⁹² Au},
  series = {Fr{\"u}hjahrstagung ... des Fachausschusses Kernphysik und Hochenergiephysik der DPG (Sektion A: Kernphysik) / Deutsche Physikalische Gesellschaft (1978)},
  journal   = {Fr{\"u}hjahrstagung ... des Fachausschusses Kernphysik und Hochenergiephysik der DPG (Sektion A: Kernphysik) / Deutsche Physikalische Gesellschaft (1978)},
  publisher = {Physik-Verlag},
  address   = {Weinheim},
  pages     = {796},
  year      = {1978},
  language  = {en}
}
@article{MuellerVeggianBochevLiederetal.1982,
  author    = {M{\"u}ller-Veggian, Mattea and Bochev, B. and Lieder, R. M. and Morek, T.},
  title     = {Band crossing and blocking in side bands of ¹⁸⁰,¹⁸² Os},
  series = {Fr{\"u}hjahrstagung ... des Fachausschusses Kernphysik und Hochenergiephysik der DPG (Sektion A: Kernphysik) / Deutsche Physikalische Gesellschaft (1982)},
  journal   = {Fr{\"u}hjahrstagung ... des Fachausschusses Kernphysik und Hochenergiephysik der DPG (Sektion A: Kernphysik) / Deutsche Physikalische Gesellschaft (1982)},
  pages     = {1273},
  year      = {1982},
  language  = {en}
}
@article{DigelTemizArtmannNishikawaetal.2005,
  author    = {Digel, Ilya and Temiz Artmann, Ayseg{\"u}l and Nishikawa, K. and Cook, M.},
  title     = {Bactericidal effects of plasma-generated cluster ions},
  series = {Medical and Biological Engineering and Computing. 43 (2005), H. 6},
  journal   = {Medical and Biological Engineering and Computing. 43 (2005), H. 6},
  isbn      = {1741-0444},
  pages     = {800 -- 807},
  year      = {2005},
  language  = {en}
}
@article{DigelAkimbekovRogachevetal.2023,
  author    = {Digel, Ilya and Akimbekov, Nuraly S. and Rogachev, Evgeniy and Pogorelova, Natalia},
  title     = {Bacterial cellulose produced by Medusomyces gisevii on glucose and sucrose: biosynthesis and structural properties},
  series = {Cellulose},
  journal   = {Cellulose},
  publisher = {Springer Science + Business Media},
  address   = {Dordrecht},
  issn      = {1572-882X (Online)},
  doi       = {10.1007/s10570-023-05592-z},
  pages     = {15 Seiten},
  year      = {2023},
  abstract  = {In this work, the effects of carbon sources and culture media on the production and structural properties of bacterial cellulose (BC) synthesized by Medusomyces gisevii have been studied. The culture medium was composed of different initial concentrations of glucose or sucrose dissolved in 0.4\% extract of plain green tea. Parameters of the culture media (titratable acidity, substrate conversion degree etc.) were monitored daily for 20 days of cultivation. The BC pellicles produced on different carbon sources were characterized in terms of biomass yield, crystallinity and morphology by field emission scanning electron microscopy (FE-SEM), atomic force microscopy and X-ray diffraction. Our results showed that Medusomyces gisevii had higher BC yields in media with sugar concentrations close to 10 g L-1 after a 18-20 days incubation period. Glucose in general lead to a higher BC yield (173 g L-1) compared to sucrose (163.5 g L-1). The BC crystallinity degree and surface roughness were higher in the samples synthetized from sucrose. Obtained FE-SEM micrographs show that the BC pellicles synthesized in the sucrose media contained densely packed tangles of cellulose fibrils whereas the BC produced in the glucose media displayed rather linear geometry of the BC fibrils without noticeable aggregates.},
  language  = {en}
}
@article{PogorelovaRogachevDigeletal.2020,
  author    = {Pogorelova, Natalia and Rogachev, Evgeniy and Digel, Ilya and Chernigova, Svetlana and Nardin, Dmitry},
  title     = {Bacterial Cellulose Nanocomposites: Morphology and Mechanical Properties},
  series = {Materials},
  volume    = {13},
  journal   = {Materials},
  number    = {12},
  publisher = {MDPI},
  address   = {Basel},
  isbn      = {1996-1944},
  doi       = {10.3390/ma13122849},
  pages     = {1 -- 16},
  year      = {2020},
  abstract  = {Bacterial cellulose (BC) is a promising material for biomedical applications due to its unique properties such as high mechanical strength and biocompatibility. This article describes the microbiological synthesis, modification, and characterization of the obtained BC-nanocomposites originating from symbiotic consortium Medusomyces gisevii. Two BC-modifications have been obtained: BC-Ag and BC-calcium phosphate (BC-Ca3(PO4)2). Structure and physicochemical properties of the BC and its modifications were investigated by scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDX), atomic force microscopy (AFM), and infrared Fourier spectroscopy as well as by measurements of mechanical and water holding/absorbing capacities. Topographic analysis of the surface revealed multicomponent thick fibrils (150-160 nm in diameter and about 15 µm in length) constituted by 50-60 nm nanofibrils weaved into a left-hand helix. Distinctive features of Ca-phosphate-modified BC samples were (a) the presence of 500-700 nm entanglements and (b) inclusions of Ca3(PO4)2 crystals. The samples impregnated with Ag nanoparticles exhibited numerous roundish inclusions, about 110 nm in diameter. The boundaries between the organic and inorganic phases were very distinct in both cases. The Ag-modified samples also showed a prominent waving pattern in the packing of nanofibrils. The obtained BC gel films possessed water-holding capacity of about 62.35 g/g. However, the dried (to a constant mass) BC-films later exhibited a low water absorption capacity (3.82 g/g). It was found that decellularized BC samples had 2.4 times larger Young's modulus and 2.2 times greater tensile strength as compared to dehydrated native BC films. We presume that this was caused by molecular compaction of the BC structure.},
  language  = {en}
}
@inproceedings{BlaneckBornheimGriegeretal.2022,
  author    = {Blaneck, Patrick Gustav and Bornheim, Tobias and Grieger, Niklas and Bialonski, Stephan},
  title     = {Automatic readability assessment of german sentences with transformer ensembles},
  series = {Proceedings of the GermEval 2022 Workshop on Text Complexity Assessment of German Text},
  booktitle = {Proceedings of the GermEval 2022 Workshop on Text Complexity Assessment of German Text},
  publisher = {Association for Computational Linguistics},
  address   = {Potsdam},
  doi       = {10.48550/arXiv.2209.04299},
  pages     = {57 -- 62},
  year      = {2022},
  abstract  = {Reliable methods for automatic readability assessment have the potential to impact a variety of fields, ranging from machine translation to self-informed learning. Recently, large language models for the German language (such as GBERT and GPT-2-Wechsel) have become available, allowing to develop Deep Learning based approaches that promise to further improve automatic readability assessment. In this contribution, we studied the ability of ensembles of fine-tuned GBERT and GPT-2-Wechsel models to reliably predict the readability of German sentences. We combined these models with linguistic features and investigated the dependence of prediction performance on ensemble size and composition. Mixed ensembles of GBERT and GPT-2-Wechsel performed better than ensembles of the same size consisting of only GBERT or GPT-2-Wechsel models. Our models were evaluated in the GermEval 2022 Shared Task on Text Complexity Assessment on data of German sentences. On out-of-sample data, our best ensemble achieved a root mean squared error of 0:435.},
  language  = {en}
}
@inproceedings{SildatkeKarwanniKraftetal.2020,
  author    = {Sildatke, Michael and Karwanni, Hendrik and Kraft, Bodo and Schmidts, Oliver and Z{\"u}ndorf, Albert},
  title     = {Automated Software Quality Monitoring in Research Collaboration Projects},
  series = {ICSEW'20: Proceedings of the IEEE/ACM 42nd International Conference on Software Engineering Workshops},
  booktitle = {ICSEW'20: Proceedings of the IEEE/ACM 42nd International Conference on Software Engineering Workshops},
  publisher = {IEEE},
  address   = {New York, NY},
  doi       = {10.1145/3387940.3391478},
  pages     = {603 -- 610},
  year      = {2020},
  abstract  = {In collaborative research projects, both researchers and practitioners work together solving business-critical challenges. These projects often deal with ETL processes, in which humans extract information from non-machine-readable documents by hand. AI-based machine learning models can help to solve this problem. Since machine learning approaches are not deterministic, their quality of output may decrease over time. This fact leads to an overall quality loss of the application which embeds machine learning models. Hence, the software qualities in development and production may differ. Machine learning models are black boxes. That makes practitioners skeptical and increases the inhibition threshold for early productive use of research prototypes. Continuous monitoring of software quality in production offers an early response capability on quality loss and encourages the use of machine learning approaches. Furthermore, experts have to ensure that they integrate possible new inputs into the model training as quickly as possible. In this paper, we introduce an architecture pattern with a reference implementation that extends the concept of Metrics Driven Research Collaboration with an automated software quality monitoring in productive use and a possibility to auto-generate new test data coming from processed documents in production. Through automated monitoring of the software quality and auto-generated test data, this approach ensures that the software quality meets and keeps requested thresholds in productive use, even during further continuous deployment and changing input data.},
  language  = {en}
}
@article{GriegerSchwabedalWendeletal.2021,
  author    = {Grieger, Niklas and Schwabedal, Justus T. C. and Wendel, Stefanie and Ritze, Yvonne and Bialonski, Stephan},
  title     = {Automated scoring of pre-REM sleep in mice with deep learning},
  series = {Scientific Reports},
  volume    = {11},
  journal   = {Scientific Reports},
  number    = {Art. 12245},
  publisher = {Springer Nature},
  address   = {London},
  issn      = {2045-2322},
  doi       = {10.1038/s41598-021-91286-0},
  year      = {2021},
  abstract  = {Reliable automation of the labor-intensive manual task of scoring animal sleep can facilitate the analysis of long-term sleep studies. In recent years, deep-learning-based systems, which learn optimal features from the data, increased scoring accuracies for the classical sleep stages of Wake, REM, and Non-REM. Meanwhile, it has been recognized that the statistics of transitional stages such as pre-REM, found between Non-REM and REM, may hold additional insight into the physiology of sleep and are now under vivid investigation. We propose a classification system based on a simple neural network architecture that scores the classical stages as well as pre-REM sleep in mice. When restricted to the classical stages, the optimized network showed state-of-the-art classification performance with an out-of-sample F1 score of 0.95 in male C57BL/6J mice. When unrestricted, the network showed lower F1 scores on pre-REM (0.5) compared to the classical stages. The result is comparable to previous attempts to score transitional stages in other species such as transition sleep in rats or N1 sleep in humans. Nevertheless, we observed that the sequence of predictions including pre-REM typically transitioned from Non-REM to REM reflecting sleep dynamics observed by human scorers. Our findings provide further evidence for the difficulty of scoring transitional sleep stages, likely because such stages of sleep are under-represented in typical data sets or show large inter-scorer variability. We further provide our source code and an online platform to run predictions with our trained network.},
  language  = {en}
}
@article{SchwabedalSippelBrandtetal.2018,
  author    = {Schwabedal, Justus T. C. and Sippel, Daniel and Brandt, Moritz D. and Bialonski, Stephan},
  title     = {Automated Classification of Sleep Stages and EEG Artifacts in Mice with Deep Learning},
  doi       = {10.48550/arXiv.1809.08443},
  year      = {2018},
  abstract  = {Sleep scoring is a necessary and time-consuming task in sleep studies. In animal models (such as mice) or in humans, automating this tedious process promises to facilitate long-term studies and to promote sleep biology as a data-driven f ield. We introduce a deep neural network model that is able to predict different states of consciousness (Wake, Non-REM, REM) in mice from EEG and EMG recordings with excellent scoring results for out-of-sample data. Predictions are made on epochs of 4 seconds length, and epochs are classified as artifactfree or not. The model architecture draws on recent advances in deep learning and in convolutional neural networks research. In contrast to previous approaches towards automated sleep scoring, our model does not rely on manually defined features of the data but learns predictive features automatically. We expect deep learning models like ours to become widely applied in different fields, automating many repetitive cognitive tasks that were previously difficult to tackle.},
  language  = {en}
}
@article{GrotendorstScottAubertFreconetal.2004,
  author    = {Grotendorst, Johannes and Scott, Tony C. and Aubert-Fr{\´e}con, Monique and Hadinger, Gis{\`e}le},
  title     = {Asymptotically exact calculation of the exchange energies of one-active-electron diatomic ions with the surface integral method / Scott, Tony C. ; Aubert-Fr{\´e}con, Monique ; Hadinger, Gis{\`e}le ; Andrae, Dirk ; Grotendorst, Johannes ; Morgan Ill, John D.},
  series = {Journal of Physics B: Atomic, Molecular and Optival Physics. 37 (2004), H. 22},
  journal   = {Journal of Physics B: Atomic, Molecular and Optival Physics. 37 (2004), H. 22},
  isbn      = {0953-4075},
  pages     = {4451 -- 4469},
  year      = {2004},
  language  = {en}
}
@article{Dikta2014,
  author    = {Dikta, Gerhard},
  title     = {Asymptotically efficient estimation under semi-parametric random censorship models},
  series = {Journal of multivariate analysis},
  volume    = {124},
  journal   = {Journal of multivariate analysis},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1095-7243 (E-Journal); 0047-259X (Print)},
  doi       = {10.1016/j.jmva.2013.10.002},
  pages     = {10 -- 24},
  year      = {2014},
  abstract  = {We study the estimation of some linear functionals which are based on an unknown lifetime distribution. The observations are assumed to be generated under the semi-parametric random censorship model (SRCM), that is, a random censorship model where the conditional expectation of the censoring indicator given the observation belongs to a parametric family. Under this setup a semi-parametric estimator of the survival function was introduced by the author. If the parametric model assumption is correct, it is known that the estimated functional which is based on this semi-parametric estimator is asymptotically at least as efficient as the corresponding one which rests on the nonparametric Kaplan-Meier estimator. In this paper we show that the estimated functional which is based on this semi-parametric estimator is asymptotically efficient with respect to the class of all regular estimators under this semi-parametric model.},
  language  = {en}
}
@article{DiktaKuehlheimMendoncaetal.2015,
  author    = {Dikta, Gerhard and K{\"u}hlheim, Ren{\´e} and Mendonca, Jorge and Una-Alcarez, Jacobo de},
  title     = {Asymptotic representation of presmoothed Kaplan-Meier integrals with covariates in a semiparametric censorship model},
  series = {Journal of Statistical Planning and Inference},
  volume    = {Vol. 171},
  journal   = {Journal of Statistical Planning and Inference},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0378-3758},
  doi       = {10.1016/j.jspi.2015.12.001},
  pages     = {10 -- 37},
  year      = {2015},
  language  = {en}
}
@article{Dikta1995,
  author    = {Dikta, Gerhard},
  title     = {Asymptotic Normality Under the Koziol-Green Model},
  series = {Communications in Statistics: Theory and Methods. 24 (1995), H. 6},
  journal   = {Communications in Statistics: Theory and Methods. 24 (1995), H. 6},
  isbn      = {0361-0926},
  pages     = {1537 -- 1549},
  year      = {1995},
  language  = {en}
}
@article{BialonskiLehnertz2013,
  author    = {Bialonski, Stephan and Lehnertz, Klaus},
  title     = {Assortative mixing in functional brain networks during epileptic seizures},
  series = {Chaos: An Interdisciplinary Journal of Nonlinear Science},
  volume    = {23},
  journal   = {Chaos: An Interdisciplinary Journal of Nonlinear Science},
  number    = {3},
  doi       = {10.1063/1.4821915},
  pages     = {033139},
  year      = {2013},
  language  = {en}
}
@article{SiqueiraBaeckerPoghossianetal.2010,
  author    = {Siqueira, Jos{\´e} R. Jr. and B{\"a}cker, Matthias and Poghossian, Arshak and Zucolotto, Valtencir and Oliveira, Osvaldo N. Jr. and Sch{\"o}ning, Michael Josef},
  title     = {Associating biosensing properties with the morphological structure of multilayers containing carbon nanotubes on field-effect devices},
  series = {Physica status solidi (a). 207 (2010), H. 4},
  journal   = {Physica status solidi (a). 207 (2010), H. 4},
  isbn      = {1862-6300},
  pages     = {781 -- 786},
  year      = {2010},
  language  = {en}
}
@article{AlbrachtArampatzisBaltzopoulos2008,
  author    = {Albracht, Kirsten and Arampatzis, A. and Baltzopoulos, V.},
  title     = {Assessment of muscle volume and physiological cross-sectional area of the human triceps surae muscle in vivo},
  series = {Journal of Biomechanics},
  volume    = {41},
  journal   = {Journal of Biomechanics},
  issn      = {0021-9290},
  doi       = {10.1016/j.jbiomech.2008.04.020},
  pages     = {2211 -- 2218},
  year      = {2008},
  language  = {en}
}
@article{BogoyavlenskiyDigelBerezin1997,
  author    = {Bogoyavlenskiy, A. P. and Digel, Ilya and Berezin, V. E.},
  title     = {Assessment of dot-blot ELISA sensitivity on membrane sorbent using various peroxidase substrates},
  year      = {1997},
  abstract  = {The sensitivity of the peroxidase reaction in dot-blot ELISA significantly depends on the substrate. The highest sensitivity is observed using benzidine and diamine- phenol combinations as the substrates due to the reaction of the coupled oxidation (NADI)},
  subject      = {Enzyme-linked immunosorbent assay},
  language  = {en}
}
@phdthesis{Engelmann2019,
  author    = {Engelmann, Ulrich M.},
  title     = {Assessing magnetic fluid hyperthermia : magnetic relaxation simulation, modeling of nanoparticle uptake inside pancreatic tumor cells and in vitro efficacy},
  publisher = {Infinite Science Publishing},
  address   = {L{\"u}beck},
  isbn      = {978-3-945954-58-4},
  year      = {2019},
  language  = {en}
}
@article{Stulpe2019,
  author    = {Stulpe, Werner},
  title     = {Aspects of the Quantum-Classical Connection Based on Statistical Maps},
  series = {Foundations of Physics},
  volume    = {49},
  journal   = {Foundations of Physics},
  number    = {6},
  publisher = {Springer},
  address   = {Berlin},
  doi       = {10.1007/s10701-019-00269-9},
  pages     = {677 -- 692},
  year      = {2019},
  language  = {en}
}
@article{HunkerGossmannRamanetal.2021,
  author    = {Hunker, Jan L. and Gossmann, Matthias and Raman, Aravind Hariharan and Linder, Peter},
  title     = {Artificial neural networks in cardiac safety assessment: Classification of chemotherapeutic compound effects on hiPSC-derived cardiomyocyte contractility},
  series = {Journal of Pharmacological and Toxicological Methods},
  volume    = {111},
  journal   = {Journal of Pharmacological and Toxicological Methods},
  number    = {Article number 107044},
  publisher = {Elsevier},
  address   = {New York},
  issn      = {1056-8719},
  doi       = {10.1016/j.vascn.2021.107044},
  year      = {2021},
  language  = {en}
}
@article{SchoeningTurekHeidenetal.2009,
  author    = {Sch{\"o}ning, Michael Josef and Turek, M. and Heiden, W. and Riesen, A. and Chhabda, T. A. and Schubert, J. and Kr{\"u}ger, P. and Keusgen, M.},
  title     = {Artificial intelligence/fuzzy logic method for analysis of combined signals from heavy metal chemical sensors},
  series = {Electrochimica Acta. 54 (2009), H. 25 Sp. Iss. SI},
  journal   = {Electrochimica Acta. 54 (2009), H. 25 Sp. Iss. SI},
  publisher = {Elsevier},
  address   = {New York},
  isbn      = {0013-4686},
  pages     = {6082 -- 6088},
  year      = {2009},
  language  = {en}
}
@incollection{Bialonski2016,
  author    = {Bialonski, Stephan},
  title     = {Are interaction clusters in epileptic networks predictive of seizures?},
  series = {Epilepsy: The Intersection of Neurosciences, Biology, Mathematics, Engineering, and Physics},
  booktitle = {Epilepsy: The Intersection of Neurosciences, Biology, Mathematics, Engineering, and Physics},
  publisher = {CRC Press},
  isbn      = {978-143983886-0},
  pages     = {349 -- 355},
  year      = {2016},
  language  = {en}
}
@article{HillenUnglaubenWirtz2002,
  author    = {Hillen, Walter and Unglauben, F. and Wirtz, G.},
  title     = {Architectures and Modeling of Distributed Image Information Systems. Unglauben, F.; Hillen, W.; Wirtz, G.},
  series = {Proceedings : July 14 - 18, 2002, Orlando, Florida, USA ; [jointly with the 8th International Conference on Information Systems Analysis and Synthesis (ISAS 2002)] / organized by IIIS, International Institute of Informatics and Systemics. Ed. by Nagib Callaos},
  journal   = {Proceedings : July 14 - 18, 2002, Orlando, Florida, USA ; [jointly with the 8th International Conference on Information Systems Analysis and Synthesis (ISAS 2002)] / organized by IIIS, International Institute of Informatics and Systemics. Ed. by Nagib Callaos},
  publisher = {IIIS},
  address   = {Orlando, Fla.},
  isbn      = {9800781501},
  year      = {2002},
  language  = {en}
}
@article{FigueroaMirandaFengShiuetal.2018,
  author    = {Figueroa-Miranda, Gabriela and Feng, Lingyan and Shiu, Simon Chi-Chin and Dirkzwager, Roderick Marshall and Cheung, Yee-Wai and Tanner, Julian Alexander and Sch{\"o}ning, Michael Josef and Offenh{\"a}usser, Andreas and Mayer, Dirk},
  title     = {Aptamer-based electrochemical biosensor for highly sensitive and selective malaria detection with adjustable dynamic response range and reusability},
  series = {Sensor and Actuators B: Chemical},
  volume    = {255},
  journal   = {Sensor and Actuators B: Chemical},
  number    = {P1},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0925-4005},
  doi       = {10.1016/j.snb.2017.07.117},
  pages     = {235 -- 243},
  year      = {2018},
  abstract  = {Malaria infection remains a significant risk for much of the population of tropical and subtropical areas, particularly in developing countries. Therefore, it is of high importance to develop sensitive, accurate and inexpensive malaria diagnosis tests. Here, we present a novel aptamer-based electrochemical biosensor (aptasensor) for malaria detection by impedance spectroscopy, through the specific recognition between a highly discriminatory DNA aptamer and its target Plasmodium falciparum lactate dehydrogenase (PfLDH). Interestingly, due to the isoelectric point (pI) of PfLDH, the aptasensor response showed an adjustable detection range based on the different protein net-charge at variable pH environments. The specific aptamer recognition allows sensitive protein detection with an expanded detection range and a low detection limit, as well as a high specificity for PfLDH compared to analogous proteins. The specific feasibility of the aptasensor is further demonstrated by detection of the target PfLDH in human serum. Furthermore, the aptasensor can be easily regenerated and thus applied for multiple usages. The robustness, sensitivity, and reusability of the presented aptasensor make it a promising candidate for point-of-care diagnostic systems.},
  language  = {en}
}
@article{Grotendorst1990,
  author    = {Grotendorst, Johannes},
  title     = {Approximating functions by means of symbolic computation and a general extrapolation method},
  series = {Computer Physics Communications. 59 (1990), H. 2},
  journal   = {Computer Physics Communications. 59 (1990), H. 2},
  isbn      = {0010-4655},
  pages     = {289 -- 301},
  year      = {1990},
  language  = {en}
}
@incollection{Weber1998,
  author    = {Weber, Hans-Joachim},
  title     = {Applied physics of compressible and incompressible fluids},
  series = {Critical care nephrology / [Hrsg.:] Claudio Ronco and Rinaldo Bellomo},
  booktitle = {Critical care nephrology / [Hrsg.:] Claudio Ronco and Rinaldo Bellomo},
  publisher = {Springer},
  address   = {Dordrecht},
  isbn      = {978-94-010-6306-7},
  pages     = {63 -- 84},
  year      = {1998},
  language  = {en}
}
@article{YoshinobuYasuhitoIwasakietal.2004,
  author    = {Yoshinobu, T. and Yasuhito, U. and Iwasaki, H. and N{\"a}ther, Niko and Sch{\"o}ning, Michael Josef and Koudelka-Hep, M.},
  title     = {Applications of the light-addressable potentiometric sensor to microfluidic devices},
  series = {Digest of technical papers : September 12 - 15, 2004, Rome, Italy, Pontificia Universitas Sancto Thoma Aquinate in Urbe / [conference chairperson: C. Di Natale].},
  journal   = {Digest of technical papers : September 12 - 15, 2004, Rome, Italy, Pontificia Universitas Sancto Thoma Aquinate in Urbe / [conference chairperson: C. Di Natale].},
  address   = {Roma},
  isbn      = {88-7621-282-5},
  pages     = {434 -- 437},
  year      = {2004},
  language  = {en}
}
@article{SchuetzHummelSchoeningetal.1999,
  author    = {Sch{\"u}tz, S. and Hummel, Hans E. and Sch{\"o}ning, Michael Josef and Schroth, P. and Kordos, P. and L{\"u}th, H. and Zimmermann, S. and Schwarz, A. and Kohl, C.-D. and Koczan, D.},
  title     = {Applications and perspectives of biosensors based on insect olfaction},
  series = {Sensor 99 : proceedings / 9th International Fair and Conference for Sensors, Transducers \& Systems, May 18 - 20, 1999, Exhibition Centre N{\"u}rnberg/Germany},
  journal   = {Sensor 99 : proceedings / 9th International Fair and Conference for Sensors, Transducers \& Systems, May 18 - 20, 1999, Exhibition Centre N{\"u}rnberg/Germany},
  publisher = {AMA Service},
  address   = {Wunstorf},
  pages     = {99 -- 104},
  year      = {1999},
  language  = {en}
}
@article{YoshinobuMoritzFingeretal.2006,
  author    = {Yoshinobu, Tatsuo and Moritz, Werner and Finger, Friedhelm and Sch{\"o}ning, Michael Josef},
  title     = {Application of thin-film amorphous silicon to chemical imaging},
  series = {Nanostructured materials and hybrid composites for gas sensors and biomedical applications : symposium held April 18-20, 2006, San Francisco , California, U.S.A.},
  journal   = {Nanostructured materials and hybrid composites for gas sensors and biomedical applications : symposium held April 18-20, 2006, San Francisco , California, U.S.A.},
  number    = {Paper 0910-A-20-01},
  editor    = {Comini, Elisabetta},
  isbn      = {9781558998711},
  pages     = {1 -- 10},
  year      = {2006},
  language  = {en}
}
@article{PoghossianBaadeEmonsetal.2001,
  author    = {Poghossian, Arshak and Baade, A. and Emons, H. and Sch{\"o}ning, Michael Josef},
  title     = {Application of ISFET for pH measurements in rain droplets},
  series = {Sensors and Actuators B. 76 (2001), H. 1-3},
  journal   = {Sensors and Actuators B. 76 (2001), H. 1-3},
  isbn      = {0925-4005},
  pages     = {634 -- 638},
  year      = {2001},
  language  = {en}
}
@article{MiyamatoSakakitaWagneretal.2015,
  author    = {Miyamato, Ko-ichiro and Sakakita, Sakura and Wagner, Torsten and Sch{\"o}ning, Michael Josef and Yoshinobu, Tatsuo},
  title     = {Application of chemical imaging sensor to in-situ pH imaging in the vicinity of a corroding metal surface},
  series = {Electrochimica Acta},
  volume    = {183},
  journal   = {Electrochimica Acta},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0013-4686},
  doi       = {10.1016/j.electacta.2015.07.184},
  pages     = {137 -- 142},
  year      = {2015},
  abstract  = {The chemical imaging sensor was applied to in-situ pH imaging of the solution in the vicinity of a corroding surface of stainless steel under potentiostatic polarization. A test piece of polished stainless steel was placed on the sensing surface leaving a narrow gap filled with artificial seawater and the stainless steel was corroded under polarization. The pH images obtained during polarization showed correspondence between the region of lower pH and the site of corrosion. It was also found that the pH value in the gap became as low as 2 by polarization, which triggered corrosion.},
  language  = {en}
}