@article{ButenwegMarinkovicSalatic2019,
  author    = {Butenweg, Christoph and Marinkovic, Marko and Salatic, Ratko},
  title     = {Experimental results of reinforced concrete frames with masonry infills under combined quasi-static in-plane and out-of-plane seismic loading},
  series = {Bulletin of Earthquake Engineering},
  volume    = {17},
  journal   = {Bulletin of Earthquake Engineering},
  publisher = {Springer},
  address   = {Berlin},
  issn      = {1573-1456},
  doi       = {10.1007/s10518-019-00602-7},
  pages     = {3397 -- 3422},
  year      = {2019},
  language  = {en}
}
@article{MarinkovicButenweg2019,
  author    = {Marinkovic, Marko and Butenweg, Christoph},
  title     = {Innovative decoupling system for the seismic protection of masonry infill walls in reinforced concrete frames},
  series = {Engineering Structures},
  volume    = {197},
  journal   = {Engineering Structures},
  number    = {Article 109435},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0141-0296},
  doi       = {10.1016/j.engstruct.2019.109435},
  year      = {2019},
  language  = {en}
}
@article{LyonsMikuckiGermanetal.2019,
  author    = {Lyons, W. Berry and Mikucki, Jill A. and German, Laura A. and Welch, Kathleen A. and Welch, Susan A. and Gardener, Christopher B. and Tulaczyk, Slawek M. and Pettit, Erin C. and Kowalski, Julia and Dachwald, Bernd},
  title     = {The Geochemistry of Englacial Brine from Taylor Glacier, Antarctica},
  series = {Journal of Geophysical Research: Biogeosciences},
  journal   = {Journal of Geophysical Research: Biogeosciences},
  publisher = {Wiley},
  address   = {Hoboken},
  issn      = {2169-8961},
  doi       = {10.1029/2018JG004411},
  year      = {2019},
  language  = {en}
}
@article{TurlybekulyPogrebnjakSukhodubetal.2019,
  author    = {Turlybekuly, Amanzhol and Pogrebnjak, Alexander and Sukhodub, L. F. and Sukhodub, Liudmyla B. and Kistaubayeva, A. S. and Savitskaya, Irina and Shokatayeva, D. H. and Bondar, Oleksandr V. and Shaimardanov, Z. K. and Plotnikov, Sergey V. and Shaimardanova, B. H. and Digel, Ilya},
  title     = {Synthesis, characterization, in vitro biocompatibility and antibacterial properties study of nanocomposite materials based on hydroxyapatite-biphasic ZnO micro- and nanoparticles embedded in Alginate matrix},
  series = {Materials Science and Engineering C},
  volume    = {104},
  journal   = {Materials Science and Engineering C},
  number    = {Article number 109965},
  publisher = {Elsevier},
  address   = {Amsterdam},
  doi       = {10.1016/j.msec.2019.109965},
  year      = {2019},
  language  = {en}
}
@article{GoettenHavermannBraunetal.2019,
  author    = {G{\"o}tten, Falk and Havermann, Marc and Braun, Carsten and Gomez, Francisco and Bil, Cees},
  title     = {RANS Simulation Validation of a Small Sensor Turret for UAVs},
  series = {Journal of Aerospace Engineering},
  volume    = {32},
  journal   = {Journal of Aerospace Engineering},
  number    = {5},
  publisher = {ASCE},
  address   = {New York},
  issn      = {1943-5525},
  doi       = {10.1061/(ASCE)AS.1943-5525.0001055},
  pages     = {Article number 04019060},
  year      = {2019},
  abstract  = {Recent Unmanned Aerial Vehicle (UAV) design procedures rely on full aircraft steady-state Reynolds-Averaged-Navier-Stokes (RANS) analyses in early design stages. Small sensor turrets are included in such simulations, even though their aerodynamic properties show highly unsteady behavior. Very little is known about the effects of this approach on the simulation outcomes of small turrets. Therefore, the flow around a model turret at a Reynolds number of 47,400 is simulated with a steady-state RANS approach and compared to experimental data. Lift, drag, and surface pressure show good agreement with the experiment. The RANS model predicts the separation location too far downstream and shows a larger recirculation region aft of the body. Both characteristic arch and horseshoe vortex structures are visualized and qualitatively match the ones found by the experiment. The Reynolds number dependence of the drag coefficient follows the trend of a sphere within a distinct range. The outcomes indicate that a steady-state RANS model of a small sensor turret is able to give results that are useful for UAV engineering purposes but might not be suited for detailed insight into flow properties.},
  language  = {en}
}
@article{GoettscheAlexopoulosDuemmleretal.2019,
  author    = {G{\"o}ttsche, Joachim and Alexopoulos, Spiros and D{\"u}mmler, Andreas and Maddineni, S. K.},
  title     = {Multi-Mirror Array Calculations With Optical Error},
  pages     = {1 -- 6},
  year      = {2019},
  abstract  = {The optical performance of a 2-axis solar concentrator was simulated with the COMSOL Multiphysics® software. The concentrator consists of a mirror array, which was created using the application builder. The mirror facets are preconfigured to form a focal point. During tracking all mirrors are moved simultaneously in a coupled mode by 2 motors in two axes, in order to keep the system in focus with the moving sun. Optical errors on each reflecting surface were implemented in combination with the solar angular cone of ± 4.65 mrad. As a result, the intercept factor of solar radiation that is available to the receiver was calculated as a function of the transversal and longitudinal angles of incidence. In addition, the intensity distribution on the receiver plane was calculated as a function of the incidence angles.},
  language  = {en}
}
@article{ValeroBungCrookston2019,
  author    = {Valero, D. and Bung, Daniel Bernhard and Crookston, B. M.},
  title     = {Closure to "Energy Dissipation of a Type III Basin under Design and Adverse Conditions for Stepped and Smooth Spillways"},
  series = {Journal of Hydraulic Engineering},
  volume    = {146},
  journal   = {Journal of Hydraulic Engineering},
  number    = {2},
  publisher = {ASCE},
  address   = {Reston, Va.},
  doi       = {10.1061/(ASCE)HY.1943-7900.0001669},
  year      = {2019},
  language  = {en}
}
@article{FunkeBeckmannAbanteriba2019,
  author    = {Funke, Harald and Beckmann, Nils and Abanteriba, Sylvester},
  title     = {An overview on dry low NOx micromix combustor development for hydrogen-rich gas turbine applications},
  series = {International Journal of Hydrogen Energy},
  volume    = {44},
  journal   = {International Journal of Hydrogen Energy},
  number    = {13},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0360-3199},
  doi       = {10.1016/j.ijhydene.2019.01.161},
  pages     = {6978 -- 6990},
  year      = {2019},
  language  = {en}
}
@article{JungStaat2019,
  author    = {Jung, Alexander and Staat, Manfred},
  title     = {Modeling and simulation of human induced pluripotent stem cell-derived cardiac tissue},
  series = {GAMM - Mitteilungen der Gesellschaft f{\"u}r Angewandte Mathematik und Mechanik},
  volume    = {42},
  journal   = {GAMM - Mitteilungen der Gesellschaft f{\"u}r Angewandte Mathematik und Mechanik},
  number    = {4},
  publisher = {Wiley},
  address   = {Weinheim},
  issn      = {1522-2608},
  doi       = {10.1002/gamm.201900002},
  pages     = {11 Seiten},
  year      = {2019},
  language  = {en}
}
@article{BronderPoghossianJessingetal.2019,
  author    = {Bronder, Thomas and Poghossian, Arshak and Jessing, Max P. and Keusgen, Michael and Sch{\"o}ning, Michael Josef},
  title     = {Surface regeneration and reusability of label-free DNA biosensors based on weak polyelectrolyte-modified capacitive field-effect structures},
  series = {Biosensors and Bioelectronics},
  volume    = {126},
  journal   = {Biosensors and Bioelectronics},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0956-5663},
  doi       = {10.1016/j.bios.2018.11.019},
  pages     = {510 -- 517},
  year      = {2019},
  language  = {en}
}
@article{SchildtBraunMarzocca2019,
  author    = {Schildt, Ph. and Braun, Carsten and Marzocca, P.},
  title     = {Metric evaluating potentials of condition-monitoring approaches for hybrid electric aircraft propulsion systems},
  series = {CEAS Aeronautical Journal},
  journal   = {CEAS Aeronautical Journal},
  publisher = {Springer},
  address   = {Berlin},
  issn      = {1869-5590},
  doi       = {10.1007/s13272-019-00411-3},
  pages     = {1 -- 14},
  year      = {2019},
  language  = {en}
}
@article{JayaramanMummidisettyLoeschetal.2019,
  author    = {Jayaraman, Chandrasekaran and Mummidisetty, Chaitanya Krishna and Loesch, Alexandra and Kaur, Sandi and Hoppe-Ludwig, Shenan and Staat, Manfred and Jayaraman, Arun},
  title     = {Postural and metabolic benefits of using a forearm support walker in older adults with impairments},
  series = {Archives of Physical Medicine and Rehabilitation},
  volume    = {Volume 100},
  journal   = {Archives of Physical Medicine and Rehabilitation},
  number    = {Issue 4},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0003-9993},
  doi       = {10.1016/j.apmr.2018.10.001},
  pages     = {638 -- 647},
  year      = {2019},
  language  = {en}
}
@article{LinderBecklerDoerretal.2019,
  author    = {Linder, Peter and Beckler, Matthias and Doerr, Leo and Stoelzle-Feix, Sonja and Fertig, Niels and Jung, Alexander and Staat, Manfred and Gossmann, Matthias},
  title     = {A new in vitro tool to investigate cardiac contractility under physiological mechanical conditions},
  series = {Journal of Pharmacological and Toxicological Methods},
  volume    = {99},
  journal   = {Journal of Pharmacological and Toxicological Methods},
  number    = {Article number 106595},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1056-8719},
  doi       = {10.1016/j.vascn.2019.05.162},
  year      = {2019},
  language  = {en}
}
@article{AchtsnichtToedterNiehuesetal.2019,
  author    = {Achtsnicht, Stefan and T{\"o}dter, Julia and Niehues, Julia and Tel{\"o}ken, Matthias and Offenh{\"a}usser, Andreas and Krause, Hans-Joachim and Schr{\"o}per, Florian},
  title     = {3D printed modular immunofiltration columns for frequency mixing-based multiplex magnetic immunodetection},
  series = {Sensors},
  volume    = {19},
  journal   = {Sensors},
  number    = {1},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {1424-8220},
  doi       = {10.3390/s19010148},
  pages     = {15 Seiten},
  year      = {2019},
  abstract  = {For performing point-of-care molecular diagnostics, magnetic immunoassays constitute a promising alternative to established enzyme-linked immunosorbent assays (ELISA) because they are fast, robust and sensitive. Simultaneous detection of multiple biomolecular targets from one body fluid sample is desired. The aim of this work is to show that multiplex magnetic immunodetection based on magnetic frequency mixing by means of modular immunofiltration columns prepared for different targets is feasible. By calculations of the magnetic response signal, the required spacing between the modules was determined. Immunofiltration columns were manufactured by 3D printing and antibody immobilization was performed in a batch approach. It was shown experimentally that two different target molecules in a sample solution could be individually detected in a single assaying step with magnetic measurements of the corresponding immobilization filters. The arrangement order of the filters and of a negative control did not influence the results. Thus, a simple and reliable approach to multi-target magnetic immunodetection was demonstrated.},
  language  = {en}
}
@article{KapelyukhHendersonScheeretal.2019,
  author    = {Kapelyukh, Yury and Henderson, Colin James and Scheer, Nico and Rode, Anja and Wolf, Charles Roland},
  title     = {Defining the contribution of CYP1A1 and CYP1A2 to drug metabolism using humanized CYP1A1/1A2 and Cyp1a1/Cyp1a2 KO mice},
  series = {Drug Metabolism and Disposition},
  journal   = {Drug Metabolism and Disposition},
  number    = {Early view},
  doi       = {10.1124/dmd.119.087718},
  pages     = {43 Seiten},
  year      = {2019},
  language  = {en}
}
@article{LeschingerBirgelHackletal.2019,
  author    = {Leschinger, Tim and Birgel, Stefan and Hackl, Michael and Staat, Manfred and M{\"u}ller, Lars Peter and Wegmann, Kilian},
  title     = {A musculoskeletal shoulder simulation of moment arms and joint reaction forces after medialization of the supraspinatus footprint in rotator cuff repair},
  series = {Computer Methods in Biomechanics and Biomedical Engineering},
  journal   = {Computer Methods in Biomechanics and Biomedical Engineering},
  number    = {Early view},
  publisher = {Taylor \& Francis},
  address   = {London},
  doi       = {10.1080/10255842.2019.1572749},
  year      = {2019},
  language  = {en}
}
@article{Gaigall2019,
  author    = {Gaigall, Daniel},
  title     = {On a new approach to the multi-sample goodness-of-fit problem},
  series = {Communications in Statistics - Simulation and Computation},
  volume    = {53},
  journal   = {Communications in Statistics - Simulation and Computation},
  number    = {10},
  publisher = {Taylor \& Francis},
  address   = {London},
  issn      = {1532-4141},
  doi       = {10.1080/03610918.2019.1618472},
  pages     = {2971 -- 2989},
  year      = {2019},
  abstract  = {Suppose we have k samples X₁,₁,…,X₁,ₙ₁,…,Xₖ,₁,…,Xₖ,ₙₖ with different sample sizes ₙ₁,…,ₙₖ and unknown underlying distribution functions F₁,…,Fₖ as observations plus k families of distribution functions {G₁(⋅,ϑ);ϑ∈Θ},…,{Gₖ(⋅,ϑ);ϑ∈Θ}, each indexed by elements ϑ from the same parameter set Θ, we consider the new goodness-of-fit problem whether or not (F₁,…,Fₖ) belongs to the parametric family {(G₁(⋅,ϑ),…,Gₖ(⋅,ϑ));ϑ∈Θ}. New test statistics are presented and a parametric bootstrap procedure for the approximation of the unknown null distributions is discussed. Under regularity assumptions, it is proved that the approximation works asymptotically, and the limiting distributions of the test statistics in the null hypothesis case are determined. Simulation studies investigate the quality of the new approach for small and moderate sample sizes. Applications to real-data sets illustrate how the idea can be used for verifying model assumptions.},
  language  = {en}
}
@article{Kurz2019,
  author    = {Kurz, Melanie},
  title     = {Images of Sweden in Germany: from Sundborn and Bullerby to Ikea},
  series = {nomad: the magazine for new design culture, business affairs and contemporary lifestyle},
  journal   = {nomad: the magazine for new design culture, business affairs and contemporary lifestyle},
  number    = {8},
  isbn      = {2513-0714},
  pages     = {136 -- 147},
  year      = {2019},
  language  = {en}
}
@article{JungMuellerStaat2019,
  author    = {Jung, Alexander and M{\"u}ller, Wolfram and Staat, Manfred},
  title     = {Optimization of the flight technique in ski jumping: the influence of wind},
  number    = {Early view},
  publisher = {Elsevier},
  address   = {Amsterdam},
  doi       = {10.1016/j.jbiomech.2019.03.023},
  year      = {2019},
  language  = {en}
}
@article{PancContiuBocanetetal.2019,
  author    = {Panc, Nicolae and Contiu, Glad and Bocanet, Vlad and Thurn, Laura and Sabau, Emilia},
  title     = {The influence of cutting technology on surface wear hardness},
  series = {Academic Journal of Manufacturing Engineering},
  volume    = {17},
  journal   = {Academic Journal of Manufacturing Engineering},
  number    = {3},
  issn      = {1583-7904},
  pages     = {205 -- 210},
  year      = {2019},
  language  = {en}
}
@article{Stulpe2019,
  author    = {Stulpe, Werner},
  title     = {Aspects of the Quantum-Classical Connection Based on Statistical Maps},
  series = {Foundations of Physics},
  volume    = {49},
  journal   = {Foundations of Physics},
  number    = {6},
  publisher = {Springer},
  address   = {Berlin},
  doi       = {10.1007/s10701-019-00269-9},
  pages     = {677 -- 692},
  year      = {2019},
  language  = {en}
}
@article{PoghossianGeisslerSchoening2019,
  author    = {Poghossian, Arshak and Geissler, Hanno and Sch{\"o}ning, Michael Josef},
  title     = {Rapid methods and sensors for milk quality monitoring and spoilage detection},
  series = {Biosensors and Bioelectronics},
  volume    = {140},
  journal   = {Biosensors and Bioelectronics},
  number    = {Article 111272},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0956-5663},
  doi       = {10.1016/j.bios.2019.04.040},
  year      = {2019},
  language  = {en}
}
@article{VoegeleRuebbelkeGovorukhaetal.2019,
  author    = {V{\"o}gele, Stefan and R{\"u}bbelke, Dirk and Govorukha, Kristina and Grajewski, Matthias},
  title     = {Socio-technical scenarios for energy-intensive industries: the future of steel production in Germany},
  series = {Climatic Change},
  journal   = {Climatic Change},
  publisher = {Springer},
  address   = {Berlin},
  issn      = {0165-0009},
  doi       = {10.1007/s10584-019-02366-0},
  pages     = {1 -- 16},
  year      = {2019},
  language  = {en}
}
@article{LeschingerBeschAydinetal.2019,
  author    = {Leschinger, Tim and Besch, Katharina and Aydin, Cansu and Staat, Manfred and Scaal, Martin and M{\"u}ller, Lars Peter and Wegmann, Kilian},
  title     = {Irreparable rotator cuff tears: a biomechanical comparison of superior capsuloligamentous complex reconstruction techniques and an interposition graft technique},
  series = {The Orthopaedic Journal of Sports Medicine},
  volume    = {7},
  journal   = {The Orthopaedic Journal of Sports Medicine},
  number    = {8},
  doi       = {10.1177/2325967119864590},
  pages     = {1 -- 5},
  year      = {2019},
  language  = {en}
}
@article{RuppHandschuhRiekeetal.2019,
  author    = {Rupp, Matthias and Handschuh, Nils and Rieke, Christian and Kuperjans, Isabel},
  title     = {Contribution of country-specific electricity mix and charging time to environmental impact of battery electric vehicles: A case study of electric buses in Germany},
  series = {Applied Energy},
  volume    = {237},
  journal   = {Applied Energy},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0306-2619},
  doi       = {10.1016/j.apenergy.2019.01.059},
  pages     = {618 -- 634},
  year      = {2019},
  language  = {en}
}
@article{OezsoyluKizildagSchoeningetal.2019,
  author    = {{\"O}zsoylu, Dua and Kizildag, Sefa and Sch{\"o}ning, Michael Josef and Wagner, Torsten},
  title     = {Effect of plasma treatment on the sensor properties of a light-addressable potentiometric sensor (LAPS)},
  series = {physica status solidi a : applications and materials sciences},
  volume    = {216},
  journal   = {physica status solidi a : applications and materials sciences},
  number    = {20},
  publisher = {Wiley},
  address   = {Weinheim},
  issn      = {1862-6319},
  doi       = {10.1002/pssa.201900259},
  pages     = {8 Seiten},
  year      = {2019},
  abstract  = {A light-addressable potentiometric sensor (LAPS) is a field-effect-based (bio-) chemical sensor, in which a desired sensing area on the sensor surface can be defined by illumination. Light addressability can be used to visualize the concentration and spatial distribution of the target molecules, e.g., H+ ions. This unique feature has great potential for the label-free imaging of the metabolic activity of living organisms. The cultivation of those organisms needs specially tailored surface properties of the sensor. O2 plasma treatment is an attractive and promising tool for rapid surface engineering. However, the potential impacts of the technique are carefully investigated for the sensors that suffer from plasma-induced damage. Herein, a LAPS with a Ta2O5 pH-sensitive surface is successfully patterned by plasma treatment, and its effects are investigated by contact angle and scanning LAPS measurements. The plasma duration of 30 s (30 W) is found to be the threshold value, where excessive wettability begins. Furthermore, this treatment approach causes moderate plasma-induced damage, which can be reduced by thermal annealing (10 min at 300 °C). These findings provide a useful guideline to support future studies, where the LAPS surface is desired to be more hydrophilic by O2 plasma treatment.},
  language  = {en}
}
@article{AchtsnichtNeuendorfFassbenderetal.2019,
  author    = {Achtsnicht, Stefan and Neuendorf, Christian and Faßbender, Tobias and N{\"o}lke, Greta and Offenh{\"a}usser, Andreas and Krause, Hans-Joachim and Schr{\"o}per, Florian},
  title     = {Sensitive and rapid detection of cholera toxin subunit B using magnetic frequency mixing detection},
  series = {Plos One},
  volume    = {14},
  journal   = {Plos One},
  number    = {7},
  publisher = {Plos},
  address   = {San Francisco},
  issn      = {1932-6203},
  doi       = {10.1371/journal.pone.0219356},
  pages     = {e0219356},
  year      = {2019},
  abstract  = {Cholera is a life-threatening disease caused by the cholera toxin (CT) as produced by some Vibrio cholerae serogroups. In this research we present a method which directly detects the toxin's B subunit (CTB) in drinking water. For this purpose we performed a magnetic sandwich immunoassay inside a 3D immunofiltration column. We used two different commercially available antibodies to capture CTB and for binding to superparamagnetic beads. ELISA experiments were performed to select the antibody combination. The beads act as labels for the magnetic frequency mixing detection technique. We show that the limit of detection depends on the type of magnetic beads. A nonlinear Hill curve was fitted to the calibration measurements by means of a custom-written python software. We achieved a sensitive and rapid detection of CTB within a broad concentration range from 0.2 ng/ml to more than 700 ng/ml.},
  language  = {en}
}
@article{AchtsnichtSchoenenbornOffenhaeusseretal.2019,
  author    = {Achtsnicht, Stefan and Sch{\"o}nenborn, Kristina and Offenh{\"a}usser, Andreas and Krause, Hans-Joachim},
  title     = {Measurement of the magnetophoretic velocity of different superparamagnetic beads},
  series = {Journal of Magnetism and Magnetic Materials},
  volume    = {477},
  journal   = {Journal of Magnetism and Magnetic Materials},
  number    = {1},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0304-8853},
  doi       = {10.1016/j.jmmm.2018.10.066},
  pages     = {244 -- 248},
  year      = {2019},
  abstract  = {The movement of magnetic beads due to a magnetic field gradient is of great interest in different application fields. In this report we present a technique based on a magnetic tweezers setup to measure the velocity factor of magnetically actuated individual superparamagnetic beads in a fluidic environment. Several beads can be tracked simultaneously in order to gain and improve statistics. Furthermore we show our results for different beads with hydrodynamic diameters between 200 and 1000 nm from diverse manufacturers. These measurement data can, for example, be used to determine design parameters for a magnetic separation system, like maximum flow rate and minimum separation time, or to select suitable beads for fixed experimental requirements.},
  language  = {en}
}
@article{AchtsnichtPourshahidiOffenhaeusseretal.2019,
  author    = {Achtsnicht, Stefan and Pourshahidi, Ali Mohammad and Offenh{\"a}usser, Andreas and Krause, Hans-Joachim},
  title     = {Multiplex detection of different magnetic beads using frequency scanning in magnetic frequency mixing technique},
  series = {Sensors},
  volume    = {19},
  journal   = {Sensors},
  number    = {11},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {1424-8220},
  doi       = {10.3390/s19112599},
  pages     = {13 Seiten},
  year      = {2019},
  abstract  = {In modern bioanalytical methods, it is often desired to detect several targets in one sample within one measurement. Immunological methods including those that use superparamagnetic beads are an important group of techniques for these applications. The goal of this work is to investigate the feasibility of simultaneously detecting different superparamagnetic beads acting as markers using the magnetic frequency mixing technique. The frequency of the magnetic excitation field is scanned while the lower driving frequency is kept constant. Due to the particles' nonlinear magnetization, mixing frequencies are generated. To record their amplitude and phase information, a direct digitization of the pickup-coil's signal with subsequent Fast Fourier Transformation is performed. By synchronizing both magnetic beads using frequency scanning in magnetic frequency mixing technique magnetic fields, a stable phase information is gained. In this research, it is shown that the amplitude of the dominant mixing component is proportional to the amount of superparamagnetic beads inside a sample. Additionally, it is shown that the phase does not show this behaviour. Excitation frequency scans of different bead types were performed, showing different phases, without correlation to their diverse amplitudes. Two commercially available beads were selected and a determination of their amount in a mixture is performed as a demonstration for multiplex measurements.},
  language  = {en}
}
@article{SchierenKleinschmidtSchmutzetal.2019,
  author    = {Schieren, Mark and Kleinschmidt, Joris and Schmutz, Axel and Loop, Torsten and Gatzweiler, Karl-Heinz and Staat, Manfred and Wappler, Frank and Defosse, Jerome},
  title     = {Comparison of forces acting on maxillary incisors during tracheal intubation with different laryngoscopy techniques: a blinded manikin study},
  series = {Anaesthesia},
  volume    = {74},
  journal   = {Anaesthesia},
  number    = {12},
  publisher = {Wiley-Blackwell},
  address   = {Oxford},
  isbn      = {1365-2044},
  doi       = {10.1111/anae.14815},
  year      = {2019},
  language  = {en}
}
@article{ScheerHendersonKapelyukhetal.2019,
  author    = {Scheer, Nico and Henderson, Colin James and Kapelyukh, Yury and Rode, Anja and Mclaren, Aileen W. and MacLeod, Alastair Kenneth and Lin, De and Wright, Jayne and Stanley, Lesley and Wolf, C. Roland},
  title     = {An extensively humanised mouse model to predict pathways of drug disposition, drug/drug interactions, and to facilitate the design of clinical trials},
  series = {Drug Metabolism and Disposition},
  journal   = {Drug Metabolism and Disposition},
  number    = {Early view},
  doi       = {10.1124/dmd.119.086397},
  pages     = {69 Seiten},
  year      = {2019},
  language  = {en}
}
@article{BaringhausGaigall2019,
  author    = {Baringhaus, Ludwig and Gaigall, Daniel},
  title     = {On an asymptotic relative efficiency concept based on expected volumes of confidence regions},
  series = {Statistics - A Journal of Theoretical and Applied Statistic},
  volume    = {53},
  journal   = {Statistics - A Journal of Theoretical and Applied Statistic},
  number    = {6},
  publisher = {Taylor \& Francis},
  address   = {London},
  issn      = {1029-4910},
  doi       = {10.1080/02331888.2019.1683560},
  pages     = {1396 -- 1436},
  year      = {2019},
  abstract  = {The paper deals with an asymptotic relative efficiency concept for confidence regions of multidimensional parameters that is based on the expected volumes of the confidence regions. Under standard conditions the asymptotic relative efficiencies of confidence regions are seen to be certain powers of the ratio of the limits of the expected volumes. These limits are explicitly derived for confidence regions associated with certain plugin estimators, likelihood ratio tests and Wald tests. Under regularity conditions, the asymptotic relative efficiency of each of these procedures with respect to each one of its competitors is equal to 1. The results are applied to multivariate normal distributions and multinomial distributions in a fairly general setting.},
  language  = {en}
}
@article{ClaerFerreinSchiffer2019,
  author    = {Claer, Mario and Ferrein, Alexander and Schiffer, Stefan},
  title     = {Calibration of a Rotating or Revolving Platform with a LiDAR Sensor},
  series = {Applied Sciences},
  volume    = {Volume 9},
  journal   = {Applied Sciences},
  number    = {issue 11, 2238},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {2076-3417},
  doi       = {10.3390/app9112238},
  pages     = {18 Seiten},
  year      = {2019},
  language  = {en}
}
@article{OrzadaSolbachGratzetal.2019,
  author    = {Orzada, Stephan and Solbach, Klaus and Gratz, Marcel and Brunheim, Sascha and Fiedler, Thomas M. and Johst, S{\"o}ren and Bitz, Andreas and Shooshtary, Samaneh and Abuelhaija, Ashraf and Voelker, Maximilian N. and Rietsch, Stefan H. G. and Kraff, Oliver and Maderwald, Stefan and Fl{\"o}ser, Martina and Oehmingen, Mark and Quick, Harald H. and Ladd, Mark E.},
  title     = {A 32-channel parallel transmit system add-on for 7T MRI},
  series = {Plos one},
  journal   = {Plos one},
  doi       = {10.1371/journal.pone.0222452},
  year      = {2019},
  language  = {en}
}
@article{BungErpicumTullis2020,
  author    = {Bung, Daniel Bernhard and Erpicum, S{\´e}bastien and Tullis, Blanke P.},
  title     = {Advances in hydraulic structures engineering},
  series = {Journal of Hydraulic Engineering},
  volume    = {147},
  journal   = {Journal of Hydraulic Engineering},
  number    = {1},
  publisher = {ASCE},
  address   = {Reston, Va.},
  issn      = {0733-9429 (Druckausgabe)},
  doi       = {10.1061/(ASCE)HY.1943-7900.0001851},
  pages     = {1 Seite},
  year      = {2020},
  language  = {en}
}
@article{GoettenHavermannBraunetal.2020,
  author    = {G{\"o}tten, Falk and Havermann, Marc and Braun, Carsten and Marino, Matthew and Bil, Cees},
  title     = {Airfoil drag at low-to-medium reynolds numbers: A novel estimation method},
  series = {AIAA Journal},
  volume    = {58},
  journal   = {AIAA Journal},
  number    = {7},
  publisher = {AIAA},
  address   = {Reston, Va.},
  issn      = {1533-385X},
  doi       = {10.2514/1.J058983},
  pages     = {2791 -- 2805},
  year      = {2020},
  abstract  = {This paper presents a novel method for airfoil drag estimation at Reynolds numbers between 4×10⁵ and 4×10⁶. The novel method is based on a systematic study of 40 airfoils applying over 600 numerical simulations and considering natural transition. The influence of the airfoil thickness-to-chord ratio, camber, and freestream Reynolds number on both friction and pressure drag is analyzed in detail. Natural transition significantly affects drag characteristics and leads to distinct drag minima for different Reynolds numbers and thickness-to-chord ratios. The results of the systematic study are used to develop empirical correlations that can accurately predict an airfoil drag at low-lift conditions. The new approach estimates a transition location based on airfoil thickness-to-chord ratio, camber, and Reynolds number. It uses the transition location in a mixed laminar-turbulent skin-friction calculation, and corrects the skin-friction coefficient for separation effects. Pressure drag is estimated separately based on correlations of thickness-to-chord ratio, camber, and Reynolds number. The novel method shows excellent accuracy when compared with wind-tunnel measurements of multiple airfoils. It is easily integrable into existing aircraft design environments and is highly beneficial in the conceptual design stage.},
  language  = {en}
}
@article{HeinEubanksHibberdetal.2020,
  author    = {Hein, Andreas M. and Eubanks, T. Marshall and Hibberd, Adam and Fries, Dan and Schneider, Jean and Lingam, Manasvi and Kennedy, Robert and Perakis, Nikolaos and Dachwald, Bernd and Kervella, Pierre},
  title     = {Interstellar Now! Missions to and sample returns from nearby interstellar objects},
  publisher = {Elsevier},
  address   = {Amsterdam},
  pages     = {1 -- 8},
  year      = {2020},
  abstract  = {The recently discovered first high velocity hyperbolic objects passing through the Solar System, 1I/'Oumuamua and 2I/Borisov, have raised the question about near term missions to Interstellar Objects. In situ spacecraft exploration of these objects will allow the direct determination of both their structure and their chemical and isotopic composition, enabling an entirely new way of studying small bodies from outside our solar system. In this paper, we map various Interstellar Object classes to mission types, demonstrating that missions to a range of Interstellar Object classes are feasible, using existing or near-term technology. We describe flyby, rendezvous and sample return missions to interstellar objects, showing various ways to explore these bodies characterizing their surface, dynamics, structure and composition. Interstellar objects likely formed very far from the solar system in both time and space; their direct exploration will constrain their formation and history, situating them within the dynamical and chemical evolution of the Galaxy. These mission types also provide the opportunity to explore solar system bodies and perform measurements in the far outer solar system.},
  language  = {en}
}
@article{AsanteAsamaniKleefeldWade2020,
  author    = {Asante-Asamani, E.O. and Kleefeld, Andreas and Wade, B.A.},
  title     = {A second-order exponential time differencing scheme for non-linear reaction-diffusion systems with dimensional splitting},
  series = {Journal of Computational Physics},
  volume    = {415},
  journal   = {Journal of Computational Physics},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0021-9991},
  doi       = {10.1016/j.jcp.2020.109490},
  year      = {2020},
  abstract  = {A second-order L-stable exponential time-differencing (ETD) method is developed by combining an ETD scheme with approximating the matrix exponentials by rational functions having real distinct poles (RDP), together with a dimensional splitting integrating factor technique. A variety of non-linear reaction-diffusion equations in two and three dimensions with either Dirichlet, Neumann, or periodic boundary conditions are solved with this scheme and shown to outperform a variety of other second-order implicit-explicit schemes. An additional performance boost is gained through further use of basic parallelization techniques.},
  language  = {en}
}
@article{RauschHarbrechtKahmannetal.2020,
  author    = {Rausch, Valentin and Harbrecht, Andreas and Kahmann, Stephanie Lucina and Fenten, Thomas and Jovanovic, Nebojsa and Hackl, Michael and M{\"u}ller, Lars P. and Staat, Manfred and Wegmann, Kilian},
  title     = {Osteosynthesis of Phalangeal Fractures: Biomechanical Comparison of Kirschner Wires, Plates, and Compression Screws},
  series = {The Journal of Hand Surgery},
  volume    = {45},
  journal   = {The Journal of Hand Surgery},
  number    = {10},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0363-5023},
  doi       = {10.1016/j.jhsa.2020.04.010},
  pages     = {987.e1 -- 987.e8},
  year      = {2020},
  abstract  = {Purpose The aim of this study was to compare several osteosynthesis techniques (intramedullary headless compression screws, T-plates, and Kirschner wires) for distal epiphyseal fractures of proximal phalanges in a human cadaveric model. Methods A total of 90 proximal phalanges from 30 specimens (index, ring, and middle fingers) were used for this study. After stripping off all soft tissue, a transverse distal epiphyseal fracture was simulated at the proximal phalanx. The 30 specimens were randomly assigned to 1 fixation technique (30 per technique), either a 3.0-mm intramedullary headless compression screw, locking plate fixation with a 2.0-mm T-plate, or 2 oblique 1.0-mm Kirschner wires. Displacement analysis (bending, distraction, and torsion) was performed using optical tracking of an applied random speckle pattern after osteosynthesis. Biomechanical testing was performed with increasing cyclic loading and with cyclic load to failure using a biaxial torsion-tension testing machine. Results Cannulated intramedullary compression screws showed significantly less displacement at the fracture site in torsional testing. Furthermore, screws were significantly more stable in bending testing. Kirschner wires were significantly less stable than plating or screw fixation in any cyclic load to failure test setup. Conclusions Intramedullary compression screws are a highly stable alternative in the treatment of transverse distal epiphyseal phalangeal fractures. Kirschner wires seem to be inferior regarding displacement properties and primary stability. Clinical relevance Fracture fixation of phalangeal fractures using plate osteosynthesis may have the advantage of a very rigid reduction, but disadvantages such as stiffness owing to the more invasive surgical approach and soft tissue irritation should be taken into account. Headless compression screws represent a minimally invasive choice for fixation with good biomechanical properties.},
  language  = {en}
}
@article{MuschallikKippReckeretal.2020,
  author    = {Muschallik, Lukas and Kipp, Carina Ronja and Recker, Inga and Bongaerts, Johannes and Pohl, Martina and Gelissen, Melanie and Sch{\"o}ning, Michael Josef and Selmer, Thorsten and Siegert, Petra},
  title     = {Synthesis of α-hydroxy ketones and vicinal diols with the Bacillus licheniformis DSM 13T butane-2, 3-diol dehydrogenase},
  series = {Journal of Biotechnology},
  volume    = {202},
  journal   = {Journal of Biotechnology},
  number    = {Vol. 324},
  publisher = {Elsevier},
  address   = {Amsterdam},
  isbn      = {2590-1559},
  doi       = {10.1016/j.jbiotec.2020.09.016},
  pages     = {61 -- 70},
  year      = {2020},
  abstract  = {The enantioselective synthesis of α-hydroxy ketones and vicinal diols is an intriguing field because of the broad applicability of these molecules. Although, butandiol dehydrogenases are known to play a key role in the production of 2,3-butandiol, their potential as biocatalysts is still not well studied. Here, we investigate the biocatalytic properties of the meso-butanediol dehydrogenase from Bacillus licheniformis DSM 13T (BlBDH). The encoding gene was cloned with an N-terminal StrepII-tag and recombinantly overexpressed in E. coli. BlBDH is highly active towards several non-physiological diketones and α-hydroxyketones with varying aliphatic chain lengths or even containing phenyl moieties. By adjusting the reaction parameters in biotransformations the formation of either the α-hydroxyketone intermediate or the diol can be controlled.},
  language  = {en}
}
@article{CapitainRossJonesMoehringetal.2020,
  author    = {Capitain, Charlotte and Ross-Jones, Jesse and M{\"o}hring, Sophie and Tippk{\"o}tter, Nils},
  title     = {Differential scanning calorimetry for quantification of polymer biodegradability in compost},
  series = {International Biodeterioration \& Biodegradation},
  volume    = {149},
  journal   = {International Biodeterioration \& Biodegradation},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0964-8305},
  doi       = {10.1016/j.ibiod.2020.104914},
  pages     = {In Press, Article number 104914},
  year      = {2020},
  abstract  = {The objective of this study is the establishment of a differential scanning calorimetry (DSC) based method for online analysis of the biodegradation of polymers in complex environments. Structural changes during biodegradation, such as an increase in brittleness or crystallinity, can be detected by carefully observing characteristic changes in DSC profiles. Until now, DSC profiles have not been used to draw quantitative conclusions about biodegradation. A new method is presented for quantifying the biodegradation using DSC data, whereby the results were validated using two reference methods. The proposed method is applied to evaluate the biodegradation of three polymeric biomaterials: polyhydroxybutyrate (PHB), cellulose acetate (CA) and Organosolv lignin. The method is suitable for the precise quantification of the biodegradability of PHB. For CA and lignin, conclusions regarding their biodegradation can be drawn with lower resolutions. The proposed method is also able to quantify the biodegradation of blends or composite materials, which differentiates it from commonly used degradation detection methods.},
  language  = {en}
}
@article{JungStaat2020,
  author    = {Jung, Alexander and Staat, Manfred},
  title     = {Erratum to "Modeling and simulation of human induced pluripotent stem cell-derived cardiac tissue" [GAMM-Mitteilungen, (2019), 42, 4, 10.1002/gamm.201900002]},
  series = {GAMM-Mitteilungen},
  volume    = {43},
  journal   = {GAMM-Mitteilungen},
  number    = {4},
  publisher = {Wiley-VCH GmbH},
  address   = {Weinheim},
  issn      = {1522-2608},
  doi       = {10.1002/gamm.202000011},
  year      = {2020},
  language  = {en}
}
@article{RauschKahmannBaltschunetal.2020,
  author    = {Rausch, Valentin and Kahmann, Stephanie Lucina and Baltschun, Christoph and Staat, Manfred and M{\"u}ller, Lars P. and Wegmann, Kilian},
  title     = {Pressure distribution to the distal biceps tendon at the radial tuberosity: a biomechanical study},
  series = {The Journal of Hand Surgery},
  volume    = {45},
  journal   = {The Journal of Hand Surgery},
  number    = {8},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0363-5023},
  doi       = {10.1016/j.jhsa.2020.01.006},
  pages     = {776.e1 -- 776.e9},
  year      = {2020},
  abstract  = {Purpose Mechanical impingement at the narrow radioulnar space of the tuberosity is believed to be an etiological factor in the injury of the distal biceps tendon. The aim of the study was to compare the pressure distribution at the proximal radioulnar space between 2 fixation techniques and the intact state. Methods Six right arms and 6 left arms from 5 female and 6 male frozen specimens were used for this study. A pressure transducer was introduced at the height of the radial tuberosity with the intact distal biceps tendon and after 2 fixation methods: the suture-anchor and the cortical button technique. The force (N), maximum pressure (kPa) applied to the radial tuberosity, and the contact area (mm²) of the radial tuberosity with the ulna were measured and differences from the intact tendon were detected from 60° supination to 60° pronation in 15° increments with the elbow in full extension and in 45° and 90° flexion of the elbow. Results With the distal biceps tendon intact, the pressures during pronation were similar regardless of extension and flexion and were the highest at 60° pronation with 90° elbow flexion (23.3 ± 53.5 kPa). After repair of the tendon, the mean peak pressure, contact area, and total force showed an increase regardless of the fixation technique. Highest peak pressures were found using the cortical button technique at 45° flexion of the elbow and 60° pronation. These differences were significantly different from the intact tendon. The contact area was significantly larger in full extension and 15°, 30°, and 60° pronation using the cortical button technique. Conclusions Pressures on the distal biceps tendon at the radial tuberosity increase during pronation, especially after repair of the tendon. Clinical relevance Mechanical impingement could play a role in both the etiology of primary distal biceps tendon ruptures and the complications occurring after fixation of the tendon using certain techniques.},
  language  = {en}
}
@article{DachwaldUlamecPostbergetal.2020,
  author    = {Dachwald, Bernd and Ulamec, Stephan and Postberg, Frank and Sohl, Frank and Vera, Jean-Pierre de and Christoph, Waldmann and Lorenz, Ralph D. and Hellard, Hugo and Biele, Jens and Rettberg, Petra},
  title     = {Key technologies and instrumentation for subsurface exploration of ocean worlds},
  series = {Space Science Reviews},
  volume    = {216},
  journal   = {Space Science Reviews},
  number    = {Art. 83},
  publisher = {Springer},
  address   = {Dordrecht},
  issn      = {1572-9672},
  doi       = {10.1007/s11214-020-00707-5},
  pages     = {45},
  year      = {2020},
  abstract  = {In this chapter, the key technologies and the instrumentation required for the subsurface exploration of ocean worlds are discussed. The focus is laid on Jupiter's moon Europa and Saturn's moon Enceladus because they have the highest potential for such missions in the near future. The exploration of their oceans requires landing on the surface, penetrating the thick ice shell with an ice-penetrating probe, and probably diving with an underwater vehicle through dozens of kilometers of water to the ocean floor, to have the chance to find life, if it exists. Technologically, such missions are extremely challenging. The required key technologies include power generation, communications, pressure resistance, radiation hardness, corrosion protection, navigation, miniaturization, autonomy, and sterilization and cleaning. Simpler mission concepts involve impactors and penetrators or - in the case of Enceladus - plume-fly-through missions.},
  language  = {en}
}
@article{MuschallikMolinnusJablonskietal.2020,
  author    = {Muschallik, Lukas and Molinnus, Denise and Jablonski, Melanie and Kipp, Carina Ronja and Bongaerts, Johannes and Pohl, Martina and Wagner, Torsten and Sch{\"o}ning, Michael Josef and Selmer, Thorsten and Siegert, Petra},
  title     = {Synthesis of α-hydroxy ketones and vicinal (R, R)-diols by Bacillus clausii DSM 8716ᵀ butanediol dehydrogenase},
  series = {RSC Advances},
  volume    = {10},
  journal   = {RSC Advances},
  publisher = {Royal Society of Chemistry (RSC)},
  address   = {Cambridge},
  issn      = {2046-2069},
  doi       = {10.1039/D0RA02066D},
  pages     = {12206 -- 12216},
  year      = {2020},
  abstract  = {α-hydroxy ketones (HK) and 1,2-diols are important building blocks for fine chemical synthesis. Here, we describe the R-selective 2,3-butanediol dehydrogenase from B. clausii DSM 8716ᵀ (BcBDH) that belongs to the metal-dependent medium chain dehydrogenases/reductases family (MDR) and catalyzes the selective asymmetric reduction of prochiral 1,2-diketones to the corresponding HK and, in some cases, the reduction of the same to the corresponding 1,2-diols. Aliphatic diketones, like 2,3-pentanedione, 2,3-hexanedione, 5-methyl-2,3-hexanedione, 3,4-hexanedione and 2,3-heptanedione are well transformed. In addition, surprisingly alkyl phenyl dicarbonyls, like 2-hydroxy-1-phenylpropan-1-one and phenylglyoxal are accepted, whereas their derivatives with two phenyl groups are not substrates. Supplementation of Mn²⁺ (1 mM) increases BcBDH's activity in biotransformations. Furthermore, the biocatalytic reduction of 5-methyl-2,3-hexanedione to mainly 5-methyl-3-hydroxy-2-hexanone with only small amounts of 5-methyl-2-hydroxy-3-hexanone within an enzyme membrane reactor is demonstrated.},
  language  = {en}
}
@article{HorbachStaatPerezVianaetal.2020,
  author    = {Horbach, Andreas and Staat, Manfred and Perez-Viana, Daniel and Simmen, Hans-Peter and Neuhaus, Valentin and Pape, Hans-Christoph and Prescher, Andreas and Ciritsis, Bernhard},
  title     = {Biomechanical in vitro examination of a standardized low-volume tubular femoroplasty},
  series = {Clinical Biomechanics},
  volume    = {80},
  journal   = {Clinical Biomechanics},
  number    = {Art. 105104},
  publisher = {Elsevier},
  address   = {Amsterdam},
  doi       = {10.1016/j.clinbiomech.2020.105104},
  year      = {2020},
  abstract  = {Background Osteoporosis is associated with the risk of fractures near the hip. Age and comorbidities increase the perioperative risk. Due to the ageing population, fracture of the proximal femur also proves to be a socio-economic problem. Preventive surgical measures have hardly been used so far. Methods 10 pairs of human femora from fresh cadavers were divided into control and low-volume femoroplasty groups and subjected to a Hayes fall-loading fracture test. The results of the respective localization and classification of the fracture site, the Singh index determined by computed tomography (CT) examination and the parameters in terms of fracture force, work to fracture and stiffness were evaluated statistically and with the finite element method. In addition, a finite element parametric study with different position angles and variants of the tubular geometry of the femoroplasty was performed. Findings Compared to the control group, the work to fracture could be increased by 33.2\%. The fracture force increased by 19.9\%. The used technique and instrumentation proved to be standardized and reproducible with an average poly(methyl methacrylate) volume of 10.5 ml. The parametric study showed the best results for the selected angle and geometry. Interpretation The cadaver studies demonstrated the biomechanical efficacy of the low-volume tubular femoroplasty. The numerical calculations confirmed the optimal choice of positioning as well as the inner and outer diameter of the tube in this setting. The standardized minimally invasive technique with the instruments developed for it could be used in further comparative studies to confirm the measured biomechanical results.},
  language  = {en}
}
@article{KnoxBruggemannGossmannetal.2020,
  author    = {Knox, Ronald and Bruggemann, Andrea and Gossmann, Matthias and Thomas, Ulrich and Horv{\´a}th, Andr{\´a}s and Dragicevic, Elena and Stoelzle-Feix, Sonja and Fertig, Niels and Jung, Alexander and Raman, Aravind Hariharan and Staat, Manfred and Linder, Peter},
  title     = {Combining physiological relevance and throughput for in vitro cardiac contractility measurement},
  series = {Biophysical Journal},
  volume    = {118},
  journal   = {Biophysical Journal},
  number    = {Issue 3, Supplement 1},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0006-3495},
  doi       = {10.1016/j.bpj.2019.11.3104},
  pages     = {570a},
  year      = {2020},
  abstract  = {Despite increasing acceptance of human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) in safety pharmacology, controversy remains about the physiological relevance of existing in vitro models for their mechanical testing. We hypothesize that existing signs of immaturity of the cell models result from an improper mechanical environment. We cultured hiPSC-CMs in a 96-well format on hyperelastic silicone membranes imitating their native mechanical environment, resulting in physiological responses to compound stimuli.We validated cell responses on the FLEXcyte 96, with a set of reference compounds covering a broad range of cellular targets, including ion channel modulators, adrenergic receptor modulators and kinase inhibitors. Acute (10 - 30 min) and chronic (up to 7 days) effects were investigated. Furthermore, the measurements were complemented with electromechanical models based on electrophysiological recordings of the used cell types.hiPSC-CMs were cultured on freely-swinging, ultra-thin and hyperelastic silicone membranes. The weight of the cell culture medium deflects the membranes downwards. Rhythmic contraction of the hiPSC-CMs resulted in dynamic deflection changes which were quantified by capacitive distance sensing. The cells were cultured for 7 days prior to compound addition. Acute measurements were conducted 10-30 minutes after compound addition in standard culture medium. For chronic treatment, compound-containing medium was replaced daily for up to 7 days. Electrophysiological properties of the employed cell types were recorded by automated patch-clamp (Patchliner) and the results were integrated into the electromechanical model of the system.Calcium channel agonist S Bay K8644 and beta-adrenergic stimulator isoproterenol induced significant positive inotropic responses without additional external stimulation. Kinase inhibitors displayed cardiotoxic effects on a functional level at low concentrations. The system-integrated analysis detected alterations in beating shape as well as frequency and arrhythmic events and we provide a quantitative measure of these.},
  language  = {en}
}
@article{DadfarCamozziDarguzyteetal.2020,
  author    = {Dadfar, Dryed Mohammadali and Camozzi, Denise and Darguzyte, Milita and Roemhild, Karolin and Varvar{\`a}, Paola and Metselaar, Josbert and Banala, Srinivas and Straub, Marcel and G{\"u}ver, Nihan and Engelmann, Ulrich M. and Slabu, Ioana and Buhl, Miriam and Leusen, Jan van and K{\"o}gerler, Paul and Hermanns-Sachweh, Benita and Schulz, Volkmar and Kiessling, Fabian and Lammers, Twan},
  title     = {Size-isolation of superparamagnetic iron oxide nanoparticles improves MRI, MPI and hyperthermia performance},
  series = {Journal of Nanobiotechnology},
  volume    = {18},
  journal   = {Journal of Nanobiotechnology},
  number    = {Article number 22},
  publisher = {Nature Portfolio},
  issn      = {1477-3155},
  doi       = {10.1186/s12951-020-0580-1},
  pages     = {1 -- 13},
  year      = {2020},
  abstract  = {Superparamagnetic iron oxide nanoparticles (SPION) are extensively used for magnetic resonance imaging (MRI) and magnetic particle imaging (MPI), as well as for magnetic fluid hyperthermia (MFH). We here describe a sequential centrifugation protocol to obtain SPION with well-defined sizes from a polydisperse SPION starting formulation, synthesized using the routinely employed co-precipitation technique. Transmission electron microscopy, dynamic light scattering and nanoparticle tracking analyses show that the SPION fractions obtained upon size-isolation are well-defined and almost monodisperse. MRI, MPI and MFH analyses demonstrate improved imaging and hyperthermia performance for size-isolated SPION as compared to the polydisperse starting mixture, as well as to commercial and clinically used iron oxide nanoparticle formulations, such as Resovist® and Sinerem®. The size-isolation protocol presented here may help to identify SPION with optimal properties for diagnostic, therapeutic and theranostic applications.},
  language  = {en}
}
@article{KreyerMuellerEsch2020,
  author    = {Kreyer, J{\"o}rg and M{\"u}ller, Marvin and Esch, Thomas},
  title     = {A Calculation Methodology for Predicting Exhaust Mass Flows and Exhaust Temperature Profiles for Heavy-Duty Vehicles},
  series = {SAE International Journal of Commercial Vehicles},
  volume    = {13},
  journal   = {SAE International Journal of Commercial Vehicles},
  number    = {2},
  publisher = {SAE International},
  address   = {Warrendale, Pa.},
  issn      = {1946-3928},
  doi       = {10.4271/02-13-02-0009},
  pages     = {129 -- 143},
  year      = {2020},
  abstract  = {The predictive control of commercial vehicle energy management systems, such as vehicle thermal management or waste heat recovery (WHR) systems, are discussed on the basis of information sources from the field of environment recognition and in combination with the determination of the vehicle system condition. In this article, a mathematical method for predicting the exhaust gas mass flow and the exhaust gas temperature is presented based on driving data of a heavy-duty vehicle. The prediction refers to the conditions of the exhaust gas at the inlet of the exhaust gas recirculation (EGR) cooler and at the outlet of the exhaust gas aftertreatment system (EAT). The heavy-duty vehicle was operated on the motorway to investigate the characteristic operational profile. In addition to the use of road gradient profile data, an evaluation of the continuously recorded distance signal, which represents the distance between the test vehicle and the road user ahead, is included in the prediction model. Using a Fourier analysis, the trajectory of the vehicle speed is determined for a defined prediction horizon. To verify the method, a holistic simulation model consisting of several hierarchically structured submodels has been developed. A map-based submodel of a combustion engine is used to determine the EGR and EAT exhaust gas mass flows and exhaust gas temperature profiles. All simulation results are validated on the basis of the recorded vehicle and environmental data. Deviations from the predicted values are analyzed and discussed.},
  language  = {en}
}
@article{HenriquesJuradoGrieseretal.2020,
  author    = {Henriques, A. and Jurado, B. and Grieser, M. and Denis-Petit, D. and Chiron, T. and Gaudefroy, L. and Glorius, J. and Langer, Christoph and Litvinov, Yu. A. and Mathieu, L. and Meot, V. and Perez-Sanchez, R. and Pibernat, J. and Reifarth, R. and Roig, O. and Thomas, B. and Thomas, B. A. and Thomas, J. C. and Tsekhanovich, I.},
  title     = {Indirect measurements of neutron cross-secti at heavy-ion storage rings},
  series = {Journal of Physics: Conference Series},
  volume    = {1668},
  journal   = {Journal of Physics: Conference Series},
  number    = {Art. 012019},
  publisher = {IOP},
  address   = {Bristol},
  doi       = {10.1088/1742-6596/1668/1/012019},
  year      = {2020},
  abstract  = {Cross sections for neutron-induced reactions of short-lived nuclei are essential for nuclear astrophysics since these reactions in the stars are responsible for the production of most heavy elements in the universe. These reactions are also key in applied domains like energy production and medicine. Nevertheless, neutron-induced cross-section measurements can be extremely challenging or even impossible to perform due to the radioactivity of the targets involved. Indirect measurements through the surrogate-reaction method can help to overcome these difficulties. The surrogate-reaction method relies on the use of an alternative reaction that will lead to the formation of the same excited nucleus as in the neutron-induced reaction of interest. The decay probabilities (for fission, neutron and gamma-ray emission) of the nucleus produced via the surrogate reaction allow one to constrain models and the prediction of the desired neutron cross sections. We propose to perform surrogate reaction measurements in inverse kinematics at heavy-ion storage rings, in particular at the CRYRING@ESR of the GSI/FAIR facility. We present the conceptual idea of the most promising setup to measure for the first time simultaneously the fission, neutron and gamma-ray emission probabilities. The results of the first simulations considering the 238U(d,d') reaction are shown, as well as new technical developments that are being carried out towards this set-up.},
  language  = {en}
}