@article{JanusAchtsnichtTempeletal.2023, author = {Janus, Kevin Alexander and Achtsnicht, Stefan and Tempel, Laura and Drinic, Aleksaner and Kopp, Alexander and Keusgen, Michael and Sch{\"o}ning, Michael Josef}, title = {Influence of fibroin membrane composition and curing parameters on the performance of a biodegradable enzymatic biosensor manufactured from Silicon-Free Carbon}, series = {Physica status solidi : pss. A, Applications and materials science}, volume = {220}, journal = {Physica status solidi : pss. A, Applications and materials science}, number = {22}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {1862-6300 (Print)}, doi = {10.1002/pssa.202300081}, pages = {10 Seiten}, year = {2023}, abstract = {Herein, fibroin, polylactide (PLA), and carbon are investigated for their suitability as biocompatible and biodegradable materials for amperometric biosensors. For this purpose, screen-printed carbon electrodes on the biodegradable substrates fibroin and PLA are modified with a glucose oxidase membrane and then encapsulated with the biocompatible material Ecoflex. The influence of different curing parameters of the carbon electrodes on the resulting biosensor characteristics is studied. The morphology of the electrodes is investigated by scanning electron microscopy, and the biosensor performance is examined by amperometric measurements of glucose (0.5-10 mM) in phosphate buffer solution, pH 7.4, at an applied potential of 1.2 V versus a Ag/AgCl reference electrode. Instead of Ecoflex, fibroin, PLA, and wound adhesive are tested as alternative encapsulation compounds: a series of swelling tests with different fibroin compositions, PLA, and Ecoflex has been performed before characterizing the most promising candidates by chronoamperometry. Therefore, the carbon electrodes are completely covered with the particular encapsulation material. Chronoamperometric measurements with H2O2 concentrations between 0.5 and 10 mM enable studying the leakage current behavior.}, language = {en} } @article{BergPostweilerSteuerDankertLeichtScholten2023, author = {Berg-Postweiler, Julia and Steuer-Dankert, Linda and Leicht-Scholten, Carmen}, title = {One size does not fit all: Applying antibias trainings in academia}, series = {The International Journal of Organizational Diversity}, volume = {24}, journal = {The International Journal of Organizational Diversity}, number = {1}, publisher = {Common Ground Research Networks}, issn = {2328-6261 (Print)}, doi = {10.18848/2328-6261/CGP/v24i01/1-23}, pages = {1 -- 23}, year = {2023}, abstract = {Antibias training is increasingly demanded and practiced in academia and industry to increase employees' sensitivity to discrimination, racism, and diversity. Under the heading of "Diversity Management," antibias trainings are mainly offered as one-off workshops intending to raise awareness of unconscious biases, create a diversity-affirming corporate culture, promote awareness of the potential of diversity, and ultimately enable the reflection of diversity in development processes. However, coming from childhood education, research and scientific articles on the sustainable effectiveness of antibias in adulthood, especially in academia, are very scarce. In order to fill this research gap, the article aims to explore how sustainable the effects of individual antibias trainings on participants' behavior are. In order to investigate this, participant observation in a qualitative pre-post setting was conducted, analyzing antibias training in an academic context. Two observers actively participated in the training sessions and documented the activities and reflection processes of the participants. Overall, the results question the effectiveness of single antibias trainings and show that a target-group adaptive approach is mandatory owing to the background of the approach in early childhood education. Therefore, antibias work needs to be adapted to the target group's needs and realities of life. Furthermore, the study reveals that single antibias trainings must be embedded in a holistic diversity management approach to stimulate sustainable reflection processes among the target group. This article is one of the first to scientifically evaluate antibias training effectiveness, especially in engineering sciences and the university context.}, language = {en} } @incollection{BaierBraunerBrillowskietal.2023, author = {Baier, Ralph and Brauner, Philipp and Brillowski, Florian and Dammers, Hannah and Liehner, Luca and P{\"u}tz, Sebastian and Schneider, Sebastian and Schollemann, Alexander and Steuer-Dankert, Linda and Vervier, Luisa and Gries, Thomas and Leicht-Scholten, Carmen and Mertens, Alexander and Nagel, Saskia K. and Schuh, G{\"u}nther and Ziefle, Martina and Nitsch, Verena}, title = {Human-centered work design for the internet of production}, series = {Internet of production - fundamentals, applications and proceedings}, booktitle = {Internet of production - fundamentals, applications and proceedings}, editor = {Brecher, Christian and Schuh, G{\"u}nther and van der Alst, Wil and Jarke, Matthias and Piller, Frank T. and Padberg, Melanie}, publisher = {Springer}, address = {Cham}, isbn = {978-3-030-98062-7}, doi = {10.1007/978-3-030-98062-7_19-1}, pages = {1 -- 23}, year = {2023}, abstract = {Like all preceding transformations of the manufacturing industry, the large-scale usage of production data will reshape the role of humans within the sociotechnical production ecosystem. To ensure that this transformation creates work systems in which employees are empowered, productive, healthy, and motivated, the transformation must be guided by principles of and research on human-centered work design. Specifically, measures must be taken at all levels of work design, ranging from (1) the work tasks to (2) the working conditions to (3) the organizational level and (4) the supra-organizational level. We present selected research across all four levels that showcase the opportunities and requirements that surface when striving for human-centered work design for the Internet of Production (IoP). (1) On the work task level, we illustrate the user-centered design of human-robot collaboration (HRC) and process planning in the composite industry as well as user-centered design factors for cognitive assistance systems. (2) On the working conditions level, we present a newly developed framework for the classification of HRC workplaces. (3) Moving to the organizational level, we show how corporate data can be used to facilitate best practice sharing in production networks, and we discuss the implications of the IoP for new leadership models. Finally, (4) on the supra-organizational level, we examine overarching ethical dimensions, investigating, e.g., how the new work contexts affect our understanding of responsibility and normative values such as autonomy and privacy. Overall, these interdisciplinary research perspectives highlight the importance and necessary scope of considering the human factor in the IoP.}, language = {en} } @inproceedings{SteuerDankert2023, author = {Steuer-Dankert, Linda}, title = {Training future skills - sustainability, interculturality \& innovation in a digital design thinking format}, series = {Proceedings of the 19th International CDIO Conference}, booktitle = {Proceedings of the 19th International CDIO Conference}, pages = {12 Seiten}, year = {2023}, abstract = {The complex questions of today for a world of tomorrow are characterized by their global impact. Solutions must therefore not only be sustainable in the sense of the three pillars of sustainability (economic, environmental, and social) but must also function globally. This goes hand in hand with the need for intercultural acceptance of developed services and products. To achieve this, engineers, as the problem solvers of the future, must be able to work in intercultural teams on appropriate solutions, and be sensitive to intercultural perspectives. To equip the engineers of the future with the so-called future skills, teaching concepts are needed in which students can acquire these methods and competencies in application-oriented formats. The presented course "Applying Design Thinking - Sustainability, Innovation and Interculturality" was developed to teach future skills from the competency areas Digital Key Competencies, Classical Competencies and Transformative Competencies. The CDIO Standard 3.0, in particular the standards 5, 6, 7 and 8, was used as a guideline. The course aims to prepare engineering students from different disciplines and cultures for their future work in an international environment by combining a digital teaching format with an interdisciplinary, transdisciplinary and intercultural setting for solving sustainability challenges. The innovative moment lies in the digital application of design thinking and the inclusion of intercultural as well as trans- and interdisciplinary perspectives in innovation development processes. In this paper, the concept of the course will be presented in detail and the particularities of a digital implementation of design thinking will be addressed. Subsequently, the potentials and challenges will be reflected and practical advice for integrating design thinking in engineering education will be given.}, language = {en} } @article{HengsbachEngelCwienczeketal.2023, author = {Hengsbach, Jan-Niklas and Engel, Mareike and Cwienczek, Marcel and Stiefelmaier, Judith and Tippk{\"o}tter, Nils and Ulber, Roland}, title = {Scalable unseparated bioelectrochemical reactors by using a carbon fiber brush as stirrer and working electrode}, series = {ChemElectroChem}, volume = {10}, journal = {ChemElectroChem}, number = {21}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {2196-0216}, doi = {10.1002/celc.202300440}, pages = {9 Seiten}, year = {2023}, abstract = {The concept of energy conversion into platform chemicals using bioelectrochemical systems (BES) has gained increasing attention in recent years, as the technology simultaneously provides an opportunity for sustainable chemical production and tackles the challenge of Power-to-X technologies. There are many approaches to realize the industrial scale of BES. One concept is to equip standard bioreactors with static electrodes. However, large installations resulted in a negative influence on various reactor parameters. In this study, we present a new single-chamber BES based on a stirred tank reactor in which the stirrer was replaced by a carbon fiber brush, performing the functions of the working electrode and the stirrer. The reactor is characterized in abiotic studies and electro-fermentations with Clostridium acetobutylicum. Compared to standard reactors an increase in butanol production of 20.14±3.66 \% shows that the new BES can be efficiently used for bioelectrochemical processes.}, language = {en} } @misc{HilleStumpfMayntzetal.2023, author = {Hille, Sebastian and Stumpf, Eike and Mayntz, Joscha and Dahmann, Peter}, title = {Prediction of sound exposure caused by a landing motor glider with recuperating propellers}, series = {AIAA SCITECH 2023 Forum}, journal = {AIAA SCITECH 2023 Forum}, publisher = {AIAA}, address = {Reston, Va.}, doi = {10.2514/6.2023-0211}, year = {2023}, abstract = {This paper presents an approach to predicting the sound exposure on the ground caused by a landing aircraft with recuperating propellers. The noise source along the trajectory of a flight specified for a steeper approach is simulated based on measurements of sound power levels and additional parameters of a single propeller placed in a wind tunnel. To validate the measured data/measurement results, these simulations are also supported by overflight measurements of a test aircraft. It is shown that the simple source models of propellers do not provide fully satisfactory results since the sound levels are estimated too low. Nevertheless, with a further reference comparison, margins for an acceptable increase in the sound power level of the aircraft on its now steeper approach path could be estimated. Thus, in this case, a +7 dB increase in SWL would not increase the SEL compared to the conventional approach within only 2 km ahead of the airfield.}, language = {en} } @inproceedings{LahrsKrisamHerrmann2023, author = {Lahrs, Lennart and Krisam, Pierre and Herrmann, Ulf}, title = {Envisioning a collaborative energy system planning platform for the energy transition at the district level}, series = {ECOS 2023. The 36th International Conference on Efficiency, Cost, Optimization, Simulation and Environmental Impact of Energy Systems}, booktitle = {ECOS 2023. The 36th International Conference on Efficiency, Cost, Optimization, Simulation and Environmental Impact of Energy Systems}, publisher = {Procedings of ECOS 2023}, doi = {10.52202/069564-0284}, pages = {3163 -- 3170}, year = {2023}, abstract = {Residential and commercial buildings account for more than one-third of global energy-related greenhouse gas emissions. Integrated multi-energy systems at the district level are a promising way to reduce greenhouse gas emissions by exploiting economies of scale and synergies between energy sources. Planning district energy systems comes with many challenges in an ever-changing environment. Computational modelling established itself as the state-of-the-art method for district energy system planning. Unfortunately, it is still cumbersome to combine standalone models to generate insights that surpass their original purpose. Ideally, planning processes could be solved by using modular tools that easily incorporate the variety of competing and complementing computational models. Our contribution is a vision for a collaborative development and application platform for multi-energy system planning tools at the district level. We present challenges of district energy system planning identified in the literature and evaluate whether this platform can help to overcome these challenges. Further, we propose a toolkit that represents the core technical elements of the platform. Lastly, we discuss community management and its relevance for the success of projects with collaboration and knowledge sharing at their core.}, language = {en} } @article{SildatkeKarwanniKraftetal.2023, author = {Sildatke, Michael and Karwanni, Hendrik and Kraft, Bodo and Z{\"u}ndorf, Albert}, title = {A distributed microservice architecture pattern for the automated generation of information extraction pipelines}, series = {SN Computer Science}, journal = {SN Computer Science}, number = {4, Article number: 833}, publisher = {Springer Singapore}, address = {Singapore}, issn = {2661-8907}, doi = {10.1007/s42979-023-02256-4}, pages = {19 Seiten}, year = {2023}, abstract = {Companies often build their businesses based on product information and therefore try to automate the process of information extraction (IE). Since the information source is usually heterogeneous and non-standardized, classic extract, transform, load techniques reach their limits. Hence, companies must implement the newest findings from research to tackle the challenges of process automation. They require a flexible and robust system that is extendable and ensures the optimal processing of the different document types. This paper provides a distributed microservice architecture pattern that enables the automated generation of IE pipelines. Since their optimal design is individual for each input document, the system ensures the ad-hoc generation of pipelines depending on specific document characteristics at runtime. Furthermore, it introduces the automated quality determination of each available pipeline and controls the integration of new microservices based on their impact on the business value. The introduced system enables fast prototyping of the newest approaches from research and supports companies in automating their IE processes. Based on the automated quality determination, it ensures that the generated pipelines always meet defined business requirements when they come into productive use.}, language = {en} } @article{NiedermeierPennerUsherovichetal.2023, author = {Niedermeier, Jana and Penner, Crystal and Usherovich, Samuel and B{\´e}langer-Champagne, Camille and Paulßen, Elisabeth and Hoehr, Cornelia}, title = {Optical Fibers as Dosimeter Detectors for Mixed Proton/Neutron Fields - A Biological Dosimeter}, series = {electronics}, volume = {12}, journal = {electronics}, number = {2}, publisher = {MDPI}, address = {Basel}, issn = {2079-9292}, doi = {10.3390/electronics12020324}, pages = {11 Seiten}, year = {2023}, abstract = {In recent years, proton therapy has gained importance as a cancer treatment modality due to its conformality with the tumor and the sparing of healthy tissue. However, in the interaction of the protons with the beam line elements and patient tissues, potentially harmful secondary neutrons are always generated. To ensure that this neutron dose is as low as possible, treatment plans could be created to also account for and minimize the neutron dose. To monitor such a treatment plan, a compact, easy to use, and inexpensive dosimeter must be developed that not only measures the physical dose, but which can also distinguish between proton and neutron contributions. To that end, plastic optical fibers with scintillation materials (Gd₂O₂S:Tb, Gd₂O₂S:Eu, and YVO₄:Eu) were irradiated with protons and neutrons. It was confirmed that sensors with different scintillation materials have different sensitivities to protons and neutrons. A combination of these three scintillators can be used to build a detector array to create a biological dosimeter.}, language = {en} } @article{HaegerGrankinWagner2023, author = {Haeger, Gerrit and Grankin, Alina and Wagner, Michaela}, title = {Construction of an Aspergillus oryzae triple amylase deletion mutant as a chassis to evaluate industrially relevant amylases using multiplex CRISPR/Cas9 editing technology}, series = {Applied Research}, journal = {Applied Research}, number = {Early View}, publisher = {Wiley-VCH}, issn = {2702-4288}, doi = {10.1002/appl.202200106}, pages = {1 -- 15}, year = {2023}, abstract = {Aspergillus oryzae is an industrially relevant organism for the secretory production of heterologous enzymes, especially amylases. The activities of potential heterologous amylases, however, cannot be quantified directly from the supernatant due to the high background activity of native α-amylase. This activity is caused by the gene products of amyA, amyB, and amyC. In this study, an in vitro CRISPR/Cas9 system was established in A. oryzae to delete these genes simultaneously. First, pyrG of A. oryzae NSAR1 was mutated by exploiting NHEJ to generate a counter-selection marker. Next, all amylase genes were deleted simultaneously by co-transforming a repair template carrying pyrG of Aspergillus nidulans and flanking sequences of amylase gene loci. The rate of obtained triple knock-outs was 47\%. We showed that triple knockouts do not retain any amylase activity in the supernatant. The established in vitro CRISPR/Cas9 system was used to achieve sequence-specific knock-in of target genes. The system was intended to incorporate a single copy of the gene of interest into the desired host for the development of screening methods. Therefore, an integration cassette for the heterologous Fpi amylase was designed to specifically target the amyB locus. The site-specific integration rate of the plasmid was 78\%, with exceptional additional integrations. Integration frequency was assessed via qPCR and directly correlated with heterologous amylase activity. Hence, we could compare the efficiency between two different signal peptides. In summary, we present a strategy to exploit CRISPR/Cas9 for gene mutation, multiplex knock-out, and the targeted knock-in of an expression cassette in A. oryzae. Our system provides straightforward strain engineering and paves the way for development of fungal screening systems.}, language = {en} } @article{Pfaff2023, author = {Pfaff, Raphael}, title = {Braking distance prediction for vehicle consist in low-speed on-sight operation: a Monte Carlo approach}, series = {Railway Engineering Science}, volume = {31}, journal = {Railway Engineering Science}, number = {2}, publisher = {SpringerOpen}, issn = {2662-4753 (eISSN)}, doi = {10.1007/s40534-023-00303-7}, pages = {135 -- 144}, year = {2023}, abstract = {The first and last mile of a railway journey, in both freight and transit applications, constitutes a high effort and is either non-productive (e.g. in the case of depot operations) or highly inefficient (e.g. in industrial railways). These parts are typically managed on-sight, i.e. with no signalling and train protection systems ensuring the freedom of movement. This is possible due to the rather short braking distances of individual vehicles and shunting consists. The present article analyses the braking behaviour of such shunting units. For this purpose, a dedicated model is developed. It is calibrated on published results of brake tests and validated against a high-definition model for low-speed applications. Based on this model, multiple simulations are executed to obtain a Monte Carlo simulation of the resulting braking distances. Based on the distribution properties and established safety levels, the risk of exceeding certain braking distances is evaluated and maximum braking distances are derived. Together with certain parameters of the system, these can serve in the design and safety assessment of driver assistance systems and automation of these processes.}, language = {en} } @article{AdelsElbersDiehletal.2023, author = {Adels, Klaudia and Elbers, Gereon and Diehl, Bernd and Monakhova, Yulia}, title = {Multicomponent analysis of dietary supplements containing glucosamine and chondroitin: comparative low- and high-field NMR spectroscopic study}, series = {Analytical Sciences}, volume = {2023}, journal = {Analytical Sciences}, publisher = {Springer Verlag}, address = {Cham}, issn = {1348-2246 (Online)}, doi = {10.1007/s44211-023-00433-2}, pages = {13 Seiten}, year = {2023}, abstract = {With the prevalence of glucosamine- and chondroitin-containing dietary supplements for people with osteoarthritis in the marketplace, it is important to have an accurate and reproducible analytical method for the quantitation of these compounds in finished products. NMR spectroscopic method based both on low- (80 MHz) and high- (500-600 MHz) field NMR instrumentation was established, compared and validated for the determination of chondroitin sulfate and glucosamine in dietary supplements. The proposed method was applied for analysis of 20 different dietary supplements. In the majority of cases, quantification results obtained on the low-field NMR spectrometer are similar to those obtained with high-field 500-600 MHz NMR devices. Validation results in terms of accuracy, precision, reproducibility, limit of detection and recovery demonstrated that the developed method is fit for purpose for the marketed products. The NMR method was extended to the analysis of methylsulfonylmethane, adulterant maltodextrin, acetate and inorganic ions. Low-field NMR can be a quicker and cheaper alternative to more expensive high-field NMR measurements for quality control of the investigated dietary supplements. High-field NMR instrumentation can be more favorable for samples with complex composition due to better resolution, simultaneously giving the possibility of analysis of inorganic species such as potassium and chloride.}, language = {en} } @inproceedings{NierlePieper2023, author = {Nierle, Elisabeth and Pieper, Martin}, title = {Measuring social impacts in engineering education to improve sustainability skills}, series = {European Society for Engineering Education (SEFI)}, booktitle = {European Society for Engineering Education (SEFI)}, doi = {10.21427/QPR4-0T22}, pages = {9 Seiten}, year = {2023}, abstract = {In times of social climate protection movements, such as Fridays for Future, the priorities of society, industry and higher education are currently changing. The consideration of sustainability challenges is increasing. In the context of sustainable development, social skills are crucial to achieving the United Nations Sustainable Development Goals (SDGs). In particular, the impact that educational activities have on people, communities and society is therefore coming to the fore. Research has shown that people with high levels of social competence are better able to manage stressful situations, maintain positive relationships and communicate effectively. They are also associated with better academic performance and career success. However, especially in engineering programs, the social pillar is underrepresented compared to the environmental and economic pillars. In response to these changes, higher education institutions should be more aware of their social impact - from individual forms of teaching to entire modules and degree programs. To specifically determine the potential for improvement and derive resulting change for further development, we present an initial framework for social impact measurement by transferring already established approaches from the business sector to the education sector. To demonstrate the applicability, we measure the key competencies taught in undergraduate engineering programs in Germany. The aim is to prepare the students for success in the modern world of work and their future contribution to sustainable development. Additionally, the university can include the results in its sustainability report. Our method can be applied to different teaching methods and enables their comparison.}, language = {en} } @book{Lauth2023, author = {Lauth, Jakob}, title = {Physical chemistry in a nutshell: Basics for engineers and scientists}, publisher = {Springer}, address = {Berlin}, isbn = {978-3-662-67636-3 (Softcover)}, doi = {10.1007/978-3-662-67637-0}, pages = {XIII, 248 Seiten}, year = {2023}, abstract = {This book is based on a multimedia course for biological and chemical engineers, which is designed to trigger students' curiosity and initiative. A solid basic knowledge of thermodynamics and kinetics is necessary for understanding many technical, chemical, and biological processes. The one-semester basic lecture course was divided into 12 workshops (chapters). Each chapter covers a practically relevant area of physical chemistry and contains the following didactic elements that make this book particularly exciting and understandable: - Links to Videos at the start of each chapter as preparation for the workshop - Key terms (in bold) for further research of your own - Comprehension questions and calculation exercises with solutions as learning checks - Key illustrations as simple, easy-to-replicate blackboard pictures Humorous cartoons for each workshop (by Faelis) additionally lighten up the text and facilitate the learning process as a mnemonic. To round out the book, the appendix includes a summary of the most popular experiments in basic physical chemistry courses, as well as suggestions for designing workshops with exhibits, experiments, and "questions of the day." Suitable for students minoring in chemistry; chemistry majors are sure to find this slimmed-down, didactically valuable book helpful as well. The book is excellent for self-study.}, language = {en} } @inproceedings{NethSchubaBrodkorbetal.2023, author = {Neth, Jannik and Schuba, Marko and Brodkorb, Karsten and Neugebauer, Georg and H{\"o}ner, Tim and Hack, Sacha}, title = {Digital forensics triage app for android}, series = {ARES '23: Proceedings of the 18th International Conference on Availability, Reliability and Security}, booktitle = {ARES '23: Proceedings of the 18th International Conference on Availability, Reliability and Security}, publisher = {ACM}, isbn = {9798400707728}, doi = {10.1145/3600160.3605017}, pages = {6 Seiten}, year = {2023}, abstract = {Digital forensics of smartphones is of utmost importance in many criminal cases. As modern smartphones store chats, photos, videos etc. that can be relevant for investigations and as they can have storage capacities of hundreds of gigabytes, they are a primary target for forensic investigators. However, it is exactly this large amount of data that is causing problems: extracting and examining the data from multiple phones seized in the context of a case is taking more and more time. This bears the risk of wasting a lot of time with irrelevant phones while there is not enough time left to analyze a phone which is worth examination. Forensic triage can help in this case: Such a triage is a preselection step based on a subset of data and is performed before fully extracting all the data from the smartphone. Triage can accelerate subsequent investigations and is especially useful in cases where time is essential. The aim of this paper is to determine which and how much data from an Android smartphone can be made directly accessible to the forensic investigator - without tedious investigations. For this purpose, an app has been developed that can be used with extremely limited storage of data in the handset and which outputs the extracted data immediately to the forensic workstation in a human- and machine-readable format.}, language = {en} } @article{DellmannGloriusLitvinovetal.2023, author = {Dellmann, Sophia Florence and Glorius, J. and Litvinov, Yu A. and Reifarth, R. and Al-Khasawneh, Kafa and Aliotta, M. and Bott, L. and Br{\"u}ckner, Benjamin and Bruno, C. G. and Chen, Ruijiu and Davinson, T. and Dickel, T. and Dillmann, Iris and Dmytriev, D. and Erbacher, P. and Freire-Fern{\´a}ndez, D. and Forstner, Oliver and Geissel, H. and G{\"o}bel, K. and Griffin, Christopher J. and Grisenti, R. and Gumberidze, Alexandre and Haettner, Emma and Hagmann, Siegbert and Heil, M. and Heß, R. and Hillenbrand, P.-M. and Joseph, R. and Jurado, B. and Kozhuharov, Christophor and Kulikov, I. and L{\"o}her, Bastian and Langer, Christoph and Leckenby, Guy and Lederer-Woods, C. and Lestinsky, M. and Litvinov, S. A. and Lorenz, B. A. and Lorenz, E. and Marsh, J. and Menz, Esther Babette and Morgenroth, T. and Petridis, N. and Pibernat, Jerome and Popp, U. and Psaltis, Athanasios and Sanjari, Shahab and Scheidenberger, C. and Sguazzin, M. and Sidhu, Ragandeep Singh and Spillmann, Uwe and Steck, M. and St{\"o}hlker, T. and Surzhykov, A. and Swartz, J. A. and T{\"o}rnqvist, H. and Varga, L. and Vescovi, Diego and Weick, H. and Weigand, M. and Woods, P. and Xing, Y. and Yamaguchi, Taiyo}, title = {Proton capture on stored radioactive ¹¹⁸Te ions}, series = {EPJ Web of Conferences}, volume = {279}, journal = {EPJ Web of Conferences}, number = {Article Number: 11018}, publisher = {EDP Sciences}, issn = {2100-014X}, doi = {10.1051/epjconf/202327911018}, pages = {1 -- 5}, year = {2023}, abstract = {Experimental determination of the cross sections of proton capture on radioactive nuclei is extremely difficult. Therefore, it is of substantial interest for the understanding of the production of the p-nuclei. For the first time, a direct measurement of proton-capture cross sections on stored, radioactive ions became possible in an energy range of interest for nuclear astrophysics. The experiment was performed at the Experimental Storage Ring (ESR) at GSI by making use of a sensitive method to measure (p,γ) and (p,n) reactions in inverse kinematics. These reaction channels are of high relevance for the nucleosyn-thesis processes in supernovae, which are among the most violent explosions in the universe and are not yet well understood. The cross section of the ¹¹⁸Te(p,γ) reaction has been measured at energies of 6 MeV/u and 7 MeV/u. The heavy ions interacted with a hydrogen gas jet target. The radiative recombination process of the fully stripped ¹¹⁸Te ions and electrons from the hydrogen target was used as a luminosity monitor. An overview of the experimental method and preliminary results from the ongoing analysis will be presented.}, language = {en} } @article{BertzMolinnusSchoeningetal.2023, author = {Bertz, Morten and Molinnus, Denise and Sch{\"o}ning, Michael Josef and Homma, Takayuki}, title = {Real-time monitoring of H₂O₂ sterilization on individual bacillus atrophaeus spores by optical sensing with trapping Raman spectroscopy}, series = {Chemosensors}, volume = {8}, journal = {Chemosensors}, number = {11}, publisher = {MDPI}, address = {Basel}, issn = {2227-9040}, doi = {10.3390/chemosensors11080445}, pages = {Artikel 445}, year = {2023}, abstract = {Hydrogen peroxide (H₂O₂), a strong oxidizer, is a commonly used sterilization agent employed during aseptic food processing and medical applications. To assess the sterilization efficiency with H₂O₂, bacterial spores are common microbial systems due to their remarkable robustness against a wide variety of decontamination strategies. Despite their widespread use, there is, however, only little information about the detailed time-resolved mechanism underlying the oxidative spore death by H₂O₂. In this work, we investigate chemical and morphological changes of individual Bacillus atrophaeus spores undergoing oxidative damage using optical sensing with trapping Raman microscopy in real-time. The time-resolved experiments reveal that spore death involves two distinct phases: (i) an initial phase dominated by the fast release of dipicolinic acid (DPA), a major spore biomarker, which indicates the rupture of the spore's core; and (ii) the oxidation of the remaining spore material resulting in the subsequent fragmentation of the spores' coat. Simultaneous observation of the spore morphology by optical microscopy corroborates these mechanisms. The dependence of the onset of DPA release and the time constant of spore fragmentation on H₂O₂ shows that the formation of reactive oxygen species from H₂O₂ is the rate-limiting factor of oxidative spore death.}, language = {en} } @inproceedings{AlhaskirTschescheLinkeetal.2023, author = {Alhaskir, Mohamed and Tschesche, Matteo and Linke, Florian and Schriewer, Elisabeth and Weber, Yvonne and Wolking, Stefan and R{\"o}hrig, Rainer and Koch, Henner and Kutafina, Ekaterina}, title = {ECG matching: an approach to synchronize ECG datasets for data quality comparisons}, series = {Proceedings of the 68th Annual Meeting of the German Association of Medical Informatics, Biometry, and Epidemiology e.V. (gmds) 2023}, volume = {307}, booktitle = {Proceedings of the 68th Annual Meeting of the German Association of Medical Informatics, Biometry, and Epidemiology e.V. (gmds) 2023}, editor = {R{\"o}hrig, Rainer and Grabe, Niels and Haag, Martin and H{\"u}bner, Ursula and Sax, Ulrich and Schmidt, Carsten Oliver and Sedlmayr, Martin and Zapf, Antonia}, publisher = {IOS Press}, isbn = {978-1-64368-428-4 (Print)}, doi = {10.3233/SHTI230718}, pages = {225 -- 232}, year = {2023}, abstract = {Clinical assessment of newly developed sensors is important for ensuring their validity. Comparing recordings of emerging electrocardiography (ECG) systems to a reference ECG system requires accurate synchronization of data from both devices. Current methods can be inefficient and prone to errors. To address this issue, three algorithms are presented to synchronize two ECG time series from different recording systems: Binned R-peak Correlation, R-R Interval Correlation, and Average R-peak Distance. These algorithms reduce ECG data to their cyclic features, mitigating inefficiencies and minimizing discrepancies between different recording systems. We evaluate the performance of these algorithms using high-quality data and then assess their robustness after manipulating the R-peaks. Our results show that R-R Interval Correlation was the most efficient, whereas the Average R-peak Distance and Binned R-peak Correlation were more robust against noisy data.}, language = {en} } @inproceedings{TischbeinKeanVertgewalletal.2023, author = {Tischbein, Franziska and Kean, Kilian and Vertgewall, Chris Martin and Ulbig, Andreas and Altherr, Lena}, title = {Determination of the topology of low-voltage distribution grids using cluster methods}, series = {27th International Conference on Electricity Distribution (CIRED 2023)}, booktitle = {27th International Conference on Electricity Distribution (CIRED 2023)}, publisher = {IEEE}, isbn = {978-1-83953-855-1}, doi = {10.1049/icp.2023.0478}, pages = {1 -- 5}, year = {2023}, abstract = {Due to the decarbonization of the energy sector, the electric distribution grids are undergoing a major transformation, which is expected to increase the load on the operating resources due to new electrical loads and distributed energy resources. Therefore, grid operators need to gradually move to active grid management in order to ensure safe and reliable grid operation. However, this requires knowledge of key grid variables, such as node voltages, which is why the mass integration of measurement technology (smart meters) is necessary. Another problem is the fact that a large part of the topology of the distribution grids is not sufficiently digitized and models are partly faulty, which means that active grid operation management today has to be carried out largely blindly. It is therefore part of current research to develop methods for determining unknown grid topologies based on measurement data. In this paper, different clustering algorithms are presented and their performance of topology detection of low voltage grids is compared. Furthermore, the influence of measurement uncertainties is investigated in the form of a sensitivity analysis.}, language = {en} } @incollection{FreyerKempt2023, author = {Freyer, Nils and Kempt, Hendrik}, title = {AI-DSS in healthcare and their power over health-insecure collectives}, series = {Justice in global health}, booktitle = {Justice in global health}, editor = {Bhakuni, Himani and Miotto, Lucas}, publisher = {Routledge}, address = {London}, isbn = {9781003399933}, doi = {10.4324/9781003399933-4}, pages = {38 -- 55}, year = {2023}, abstract = {AI-based systems are nearing ubiquity not only in everyday low-stakes activities but also in medical procedures. To protect patients and physicians alike, explainability requirements have been proposed for the operation of AI-based decision support systems (AI-DSS), which adds hurdles to the productive use of AI in clinical contexts. This raises two questions: Who decides these requirements? And how should access to AI-DSS be provided to communities that reject these standards (particularly when such communities are expert-scarce)? This chapter investigates a dilemma that emerges from the implementation of global AI governance. While rejecting global AI governance limits the ability to help communities in need, global AI governance risks undermining and subjecting health-insecure communities to the force of the neo-colonial world order. For this, this chapter first surveys the current landscape of AI governance and introduces the approach of relational egalitarianism as key to (global health) justice. To discuss the two horns of the referred dilemma, the core power imbalances faced by health-insecure collectives (HICs) are examined. The chapter argues that only strong demands of a dual strategy towards health-secure collectives can both remedy the immediate needs of HICs and enable them to become healthcare independent.}, language = {en} } @inproceedings{SchulteTiggesMatheisRekeetal.2023, author = {Schulte-Tigges, Joschua and Matheis, Dominik and Reke, Michael and Walter, Thomas and Kaszner, Daniel}, title = {Demonstrating a V2X enabled system for transition of control and minimum risk manoeuvre when leaving the operational design domain}, series = {HCII 2023: HCI in Mobility, Transport, and Automotive Systems}, booktitle = {HCII 2023: HCI in Mobility, Transport, and Automotive Systems}, editor = {Kr{\"o}mker, Heidi}, publisher = {Springer}, address = {Cham}, isbn = {978-3-031-35677-3 (Print)}, doi = {10.1007/978-3-031-35678-0_12}, pages = {200 -- 210}, year = {2023}, abstract = {Modern implementations of driver assistance systems are evolving from a pure driver assistance to a independently acting automation system. Still these systems are not covering the full vehicle usage range, also called operational design domain, which require the human driver as fall-back mechanism. Transition of control and potential minimum risk manoeuvres are currently research topics and will bridge the gap until full autonomous vehicles are available. The authors showed in a demonstration that the transition of control mechanisms can be further improved by usage of communication technology. Receiving the incident type and position information by usage of standardised vehicle to everything (V2X) messages can improve the driver safety and comfort level. The connected and automated vehicle's software framework can take this information to plan areas where the driver should take back control by initiating a transition of control which can be followed by a minimum risk manoeuvre in case of an unresponsive driver. This transition of control has been implemented in a test vehicle and was presented to the public during the IEEE IV2022 (IEEE Intelligent Vehicle Symposium) in Aachen, Germany.}, language = {en} } @article{MoraisSumanSchoeningetal.2023, author = {Morais, Paulo V. and Suman, Pedro H. and Sch{\"o}ning, Michael Josef and Siqueira Junior, Jos{\´e} R. and Orlandi, Marcelo O.}, title = {Layer-by-layer film based on Sn₃O₄ nanobelts as sensing units to detect heavy metals using a capacitive field-effect sensor platform}, series = {Chemosensors}, volume = {11}, journal = {Chemosensors}, number = {8}, publisher = {MDPI}, address = {Basel}, issn = {2227-9040}, doi = {10.3390/chemosensors11080436}, pages = {Artikel 436}, year = {2023}, abstract = {Lead and nickel, as heavy metals, are still used in industrial processes, and are classified as "environmental health hazards" due to their toxicity and polluting potential. The detection of heavy metals can prevent environmental pollution at toxic levels that are critical to human health. In this sense, the electrolyte-insulator-semiconductor (EIS) field-effect sensor is an attractive sensing platform concerning the fabrication of reusable and robust sensors to detect such substances. This study is aimed to fabricate a sensing unit on an EIS device based on Sn₃O₄ nanobelts embedded in a polyelectrolyte matrix of polyvinylpyrrolidone (PVP) and polyacrylic acid (PAA) using the layer-by-layer (LbL) technique. The EIS-Sn₃O₄ sensor exhibited enhanced electrochemical performance for detecting Pb²⁺ and Ni²⁺ ions, revealing a higher affinity for Pb²⁺ ions, with sensitivities of ca. 25.8 mV/decade and 2.4 mV/decade, respectively. Such results indicate that Sn₃O₄ nanobelts can contemplate a feasible proof-of-concept capacitive field-effect sensor for heavy metal detection, envisaging other future studies focusing on environmental monitoring.}, language = {en} } @inproceedings{KueppersSchubaNeugebaueretal.2023, author = {K{\"u}ppers, Malte and Schuba, Marko and Neugebauer, Georg and H{\"o}ner, Tim and Hack, Sacha}, title = {Security analysis of the KNX smart building protocol}, series = {ARES '23: Proceedings of the 18th International Conference on Availability, Reliability and Security}, booktitle = {ARES '23: Proceedings of the 18th International Conference on Availability, Reliability and Security}, publisher = {ACM}, doi = {10.1145/3600160.3605167}, pages = {1 -- 7}, year = {2023}, abstract = {KNX is a protocol for smart building automation, e.g., for automated heating, air conditioning, or lighting. This paper analyses and evaluates state-of-the-art KNX devices from manufacturers Merten, Gira and Siemens with respect to security. On the one hand, it is investigated if publicly known vulnerabilities like insecure storage of passwords in software, unencrypted communication, or denialof-service attacks, can be reproduced in new devices. On the other hand, the security is analyzed in general, leading to the discovery of a previously unknown and high risk vulnerability related to so-called BCU (authentication) keys.}, language = {en} } @phdthesis{Gaigall2023, author = {Gaigall, Daniel}, title = {On selected problems in multivariate analysis}, doi = {10.15488/14304}, pages = {17 Seiten}, year = {2023}, abstract = {Selected problems in the field of multivariate statistical analysis are treated. Thereby, one focus is on the paired sample case. Among other things, statistical testing problems of marginal homogeneity are under consideration. In detail, properties of Hotelling's T² test in a special parametric situation are obtained. Moreover, the nonparametric problem of marginal homogeneity is discussed on the basis of possibly incomplete data. In the bivariate data case, properties of the Hoeffding-Blum-Kiefer-Rosenblatt independence test statistic on the basis of partly not identically distributed data are investigated. Similar testing problems are treated within the scope of the application of a result for the empirical process of the concomitants for partly categorial data. Furthermore, testing changes in the modeled solvency capital requirement of an insurance company by means of a paired sample from an internal risk model is discussed. Beyond the paired sample case, a new asymptotic relative efficiency concept based on the expected volumes of multidimensional confidence regions is introduced. Besides, a new approach for the treatment of the multi-sample goodness-of-fit problem is presented. Finally, a consistent test for the treatment of the goodness-of-fit problem is developed for the background of huge or infinite dimensional data.}, language = {en} } @article{SchulzeFeyerlPischinger2023, author = {Schulze, Sven and Feyerl, G{\"u}nter and Pischinger, Stefan}, title = {Advanced ECMS for hybrid electric heavy-duty trucks with predictive battery discharge and adaptive operating strategy under real driving conditions}, series = {Energies}, volume = {16}, journal = {Energies}, number = {13}, publisher = {MDPI}, address = {Basel}, issn = {1996-1073}, doi = {10.3390/en16135171}, pages = {29 Seiten, Art. Nr.: 5171}, year = {2023}, abstract = {To fulfil the CO2 emission reduction targets of the European Union (EU), heavy-duty (HD) trucks need to operate 15\% more efficiently by 2025 and 30\% by 2030. Their electrification is necessary as conventional HD trucks are already optimized for the long-haul application. The resulting hybrid electric vehicle (HEV) truck gains most of the fuel saving potential by the recuperation of potential energy and its consecutive utilization. The key to utilizing the full potential of HEV-HD trucks is to maximize the amount of recuperated energy and ensure its intelligent usage while keeping the operating point of the internal combustion engine as efficient as possible. To achieve this goal, an intelligent energy management strategy (EMS) based on ECMS is developed for a parallel HEV-HD truck which uses predictive discharge of the battery and adaptive operating strategy regarding the height profile and the vehicle mass. The presented EMS can reproduce the global optimal operating strategy over long phases and lead to a fuel saving potential of up to 2\% compared with a heuristic strategy. Furthermore, the fuel saving potential is correlated with the investigated boundary conditions to deepen the understanding of the impact of intelligent EMS for HEV-HD trucks.}, language = {en} } @inproceedings{BuesgenKloeserKohletal.2023, author = {B{\"u}sgen, Andr{\´e} and Kl{\"o}ser, Lars and Kohl, Philipp and Schmidts, Oliver and Kraft, Bodo and Z{\"u}ndorf, Albert}, title = {From cracked accounts to fake IDs: user profiling on German telegram black market channels}, series = {Data Management Technologies and Applications}, booktitle = {Data Management Technologies and Applications}, editor = {Cuzzocrea, Alfredo and Gusikhin, Oleg and Hammoudi, Slimane and Quix, Christoph}, publisher = {Springer}, address = {Cham}, isbn = {978-3-031-37889-8 (Print)}, doi = {10.1007/978-3-031-37890-4_9}, pages = {176 -- 202}, year = {2023}, abstract = {Messenger apps like WhatsApp and Telegram are frequently used for everyday communication, but they can also be utilized as a platform for illegal activity. Telegram allows public groups with up to 200.000 participants. Criminals use these public groups for trading illegal commodities and services, which becomes a concern for law enforcement agencies, who manually monitor suspicious activity in these chat rooms. This research demonstrates how natural language processing (NLP) can assist in analyzing these chat rooms, providing an explorative overview of the domain and facilitating purposeful analyses of user behavior. We provide a publicly available corpus of annotated text messages with entities and relations from four self-proclaimed black market chat rooms. Our pipeline approach aggregates the extracted product attributes from user messages to profiles and uses these with their sold products as features for clustering. The extracted structured information is the foundation for further data exploration, such as identifying the top vendors or fine-granular price analyses. Our evaluation shows that pretrained word vectors perform better for unsupervised clustering than state-of-the-art transformer models, while the latter is still superior for sequence labeling.}, language = {en} } @inproceedings{KohlFreyerKraemeretal.2023, author = {Kohl, Philipp and Freyer, Nils and Kr{\"a}mer, Yoka and Werth, Henri and Wolf, Steffen and Kraft, Bodo and Meinecke, Matthias and Z{\"u}ndorf, Albert}, title = {ALE: a simulation-based active learning evaluation framework for the parameter-driven comparison of query strategies for NLP}, series = {Deep Learning Theory and Applications}, booktitle = {Deep Learning Theory and Applications}, editor = {Conte, Donatello and Fred, Ana and Gusikhin, Oleg and Sansone, Carlo}, publisher = {Springer}, address = {Cham}, isbn = {978-3-031-39058-6 (Print)}, doi = {10.1007/978-3-031-39059-3_16}, pages = {235 -- 253}, year = {2023}, abstract = {Supervised machine learning and deep learning require a large amount of labeled data, which data scientists obtain in a manual, and time-consuming annotation process. To mitigate this challenge, Active Learning (AL) proposes promising data points to annotators they annotate next instead of a subsequent or random sample. This method is supposed to save annotation effort while maintaining model performance. However, practitioners face many AL strategies for different tasks and need an empirical basis to choose between them. Surveys categorize AL strategies into taxonomies without performance indications. Presentations of novel AL strategies compare the performance to a small subset of strategies. Our contribution addresses the empirical basis by introducing a reproducible active learning evaluation (ALE) framework for the comparative evaluation of AL strategies in NLP. The framework allows the implementation of AL strategies with low effort and a fair data-driven comparison through defining and tracking experiment parameters (e.g., initial dataset size, number of data points per query step, and the budget). ALE helps practitioners to make more informed decisions, and researchers can focus on developing new, effective AL strategies and deriving best practices for specific use cases. With best practices, practitioners can lower their annotation costs. We present a case study to illustrate how to use the framework.}, language = {en} } @article{WaldvogelFreylerHelmetal.2023, author = {Waldvogel, Janice and Freyler, Kathrin and Helm, Michael and Monti, Elena and St{\"a}udle, Benjamin and Gollhofer, Albert and Narici, Marco V. and Ritzmann, Ramona and Albracht, Kirsten}, title = {Changes in gravity affect neuromuscular control, biomechanics, and muscle-tendon mechanics in energy storage and dissipation tasks}, series = {Journal of Applied Physiology}, volume = {134}, journal = {Journal of Applied Physiology}, number = {1}, publisher = {American Physiological Society}, address = {Bethesda, Md.}, issn = {1522-1601 (Onlineausgabe)}, doi = {10.1152/japplphysiol.00279.2022}, pages = {190 -- 202}, year = {2023}, abstract = {This study evaluates neuromechanical control and muscle-tendon interaction during energy storage and dissipation tasks in hypergravity. During parabolic flights, while 17 subjects performed drop jumps (DJs) and drop landings (DLs), electromyography (EMG) of the lower limb muscles was combined with in vivo fascicle dynamics of the gastrocnemius medialis, two-dimensional (2D) kinematics, and kinetics to measure and analyze changes in energy management. Comparisons were made between movement modalities executed in hypergravity (1.8 G) and gravity on ground (1 G). In 1.8 G, ankle dorsiflexion, knee joint flexion, and vertical center of mass (COM) displacement are lower in DJs than in DLs; within each movement modality, joint flexion amplitudes and COM displacement demonstrate higher values in 1.8 G than in 1 G. Concomitantly, negative peak ankle joint power, vertical ground reaction forces, and leg stiffness are similar between both movement modalities (1.8 G). In DJs, EMG activity in 1.8 G is lower during the COM deceleration phase than in 1 G, thus impairing quasi-isometric fascicle behavior. In DLs, EMG activity before and during the COM deceleration phase is higher, and fascicles are stretched less in 1.8 G than in 1 G. Compared with the situation in 1 G, highly task-specific neuromuscular activity is diminished in 1.8 G, resulting in fascicle lengthening in both movement modalities. Specifically, in DJs, a high magnitude of neuromuscular activity is impaired, resulting in altered energy storage. In contrast, in DLs, linear stiffening of the system due to higher neuromuscular activity combined with lower fascicle stretch enhances the buffering function of the tendon, and thus the capacity to safely dissipate energy.}, language = {en} } @article{HeieisBoeckerD'Angeloetal.2023, author = {Heieis, Jule and B{\"o}cker, Jonas and D'Angelo, Olfa and Mittag, Uwe and Albracht, Kirsten and Sch{\"o}nau, Eckhard and Meyer, Andreas and Voigtmann, Thomas and Rittweger, J{\"o}rn}, title = {Curvature of gastrocnemius muscle fascicles as function of muscle-tendon complex length and contraction in humans}, series = {Physiological Reports}, volume = {11}, journal = {Physiological Reports}, number = {11}, publisher = {Wiley}, issn = {2051-817X}, doi = {10.14814/phy2.15739}, pages = {e15739, Seite 1-11}, year = {2023}, abstract = {It has been shown that muscle fascicle curvature increases with increasing contraction level and decreasing muscle-tendon complex length. The analyses were done with limited examination windows concerning contraction level, muscle-tendon complex length, and/or intramuscular position of ultrasound imaging. With this study we aimed to investigate the correlation between fascicle arching and contraction, muscle-tendon complex length and their associated architectural parameters in gastrocnemius muscles to develop hypotheses concerning the fundamental mechanism of fascicle curving. Twelve participants were tested in five different positions (90°/105°*, 90°/90°*, 135°/90°*, 170°/90°*, and 170°/75°*; *knee/ankle angle). They performed isometric contractions at four different contraction levels (5\%, 25\%, 50\%, and 75\% of maximum voluntary contraction) in each position. Panoramic ultrasound images of gastrocnemius muscles were collected at rest and during constant contraction. Aponeuroses and fascicles were tracked in all ultrasound images and the parameters fascicle curvature, muscle-tendon complex strain, contraction level, pennation angle, fascicle length, fascicle strain, intramuscular position, sex and age group were analyzed by linear mixed effect models. Mean fascicle curvature of the medial gastrocnemius increased with contraction level (+5 m-1 from 0\% to 100\%; p = 0.006). Muscle-tendon complex length had no significant impact on mean fascicle curvature. Mean pennation angle (2.2 m-1 per 10°; p < 0.001), inverse mean fascicle length (20 m-1 per cm-1; p = 0.003), and mean fascicle strain (-0.07 m-1 per +10\%; p = 0.004) correlated with mean fascicle curvature. Evidence has also been found for intermuscular, intramuscular, and sex-specific intramuscular differences of fascicle curving. Pennation angle and the inverse fascicle length show the highest predictive capacities for fascicle curving. Due to the strong correlations between pennation angle and fascicle curvature and the intramuscular pattern of curving we suggest for future studies to examine correlations between fascicle curvature and intramuscular fluid pressure.}, language = {en} } @article{TrappLammersEngudaretal.2023, author = {Trapp, Svenja and Lammers, Tom and Engudar, Gokce and Hoehr, Cornelia and Denkova, Antonia G. and Paulßen, Elisabeth and de Kruijff, Robin M.}, title = {Membrane-based microfluidic solvent extraction of Ga-68 from aqueous Zn solutions: towards an automated cyclotron production loop}, series = {EJNMMI Radiopharmacy and Chemistry}, volume = {2023}, journal = {EJNMMI Radiopharmacy and Chemistry}, number = {8, Article number: 9}, publisher = {Springer Nature}, issn = {2365-421X}, doi = {10.1186/s41181-023-00195-2}, pages = {1 -- 14}, year = {2023}, language = {en} } @inproceedings{FreyerThewesMeinecke2023, author = {Freyer, Nils and Thewes, Dustin and Meinecke, Matthias}, title = {GUIDO: a hybrid approach to guideline discovery \& ordering from natural language texts}, series = {Proceedings of the 12th International Conference on Data Science, Technology and Applications DATA - Volume 1}, booktitle = {Proceedings of the 12th International Conference on Data Science, Technology and Applications DATA - Volume 1}, editor = {Gusikhin, Oleg and Hammoudi, Slimane and Cuzzocrea, Alfredo}, isbn = {978-989-758-664-4}, issn = {2184-285X}, doi = {10.5220/0012084400003541}, pages = {335 -- 342}, year = {2023}, abstract = {Extracting workflow nets from textual descriptions can be used to simplify guidelines or formalize textual descriptions of formal processes like business processes and algorithms. The task of manually extracting processes, however, requires domain expertise and effort. While automatic process model extraction is desirable, annotating texts with formalized process models is expensive. Therefore, there are only a few machine-learning-based extraction approaches. Rule-based approaches, in turn, require domain specificity to work well and can rarely distinguish relevant and irrelevant information in textual descriptions. In this paper, we present GUIDO, a hybrid approach to the process model extraction task that first, classifies sentences regarding their relevance to the process model, using a BERT-based sentence classifier, and second, extracts a process model from the sentences classified as relevant, using dependency parsing. The presented approach achieves significantly better resul ts than a pure rule-based approach. GUIDO achieves an average behavioral similarity score of 0.93. Still, in comparison to purely machine-learning-based approaches, the annotation costs stay low.}, language = {en} } @inproceedings{KloeserBuesgenKohletal.2023, author = {Kl{\"o}ser, Lars and B{\"u}sgen, Andr{\´e} and Kohl, Philipp and Kraft, Bodo and Z{\"u}ndorf, Albert}, title = {Explaining relation classification models with semantic extents}, series = {Deep Learning Theory and Applications}, booktitle = {Deep Learning Theory and Applications}, editor = {Conte, Donatello and Fred, Ana and Gusikhin, Oleg and Sansone, Carlo}, publisher = {Springer}, address = {Cham}, isbn = {978-3-031-39058-6 (Print)}, doi = {10.1007/978-3-031-39059-3_13}, pages = {189 -- 208}, year = {2023}, abstract = {In recent years, the development of large pretrained language models, such as BERT and GPT, significantly improved information extraction systems on various tasks, including relation classification. State-of-the-art systems are highly accurate on scientific benchmarks. A lack of explainability is currently a complicating factor in many real-world applications. Comprehensible systems are necessary to prevent biased, counterintuitive, or harmful decisions. We introduce semantic extents, a concept to analyze decision patterns for the relation classification task. Semantic extents are the most influential parts of texts concerning classification decisions. Our definition allows similar procedures to determine semantic extents for humans and models. We provide an annotation tool and a software framework to determine semantic extents for humans and models conveniently and reproducibly. Comparing both reveals that models tend to learn shortcut patterns from data. These patterns are hard to detect with current interpretability methods, such as input reductions. Our approach can help detect and eliminate spurious decision patterns during model development. Semantic extents can increase the reliability and security of natural language processing systems. Semantic extents are an essential step in enabling applications in critical areas like healthcare or finance. Moreover, our work opens new research directions for developing methods to explain deep learning models.}, language = {en} } @unpublished{GreinerJerominSitholeetal.2023, author = {Greiner, Lasse and Jeromin, G{\"u}nter Erich and Sithole, Patience and Petersen, Soenke}, title = {Preprint: Studies on the enzymatic reduction of levulinic acid using Chiralidon-R and Chiralidon-S}, series = {ChemRxiv}, journal = {ChemRxiv}, doi = {10.26434/chemrxiv-2023-jlvcv}, pages = {13 Seiten}, year = {2023}, abstract = {The enzymatic reduction of levulinic acid by the chiral catalysts Chiralidon-R and Chiralidon-S which are commercially available superabsorbed alcohol dehydrogenases is described. The Chiralidon®-R/S reduces the levulinic acid to the (R,S)-4-hydroxy valeric acid and the (R)- or (S)- gamma-valerolactone.}, language = {en} } @article{ChengWollertChenetal.2023, author = {Cheng, Chi-Tsun and Wollert, J{\"o}rg and Chen, Xi and Fapojuwo, Abraham O.}, title = {Guest Editorial : Circuits and Systems for Industry X.0 Applications}, series = {IEEE Journal on Emerging and Selected Topics in Circuits and Systems}, volume = {13}, journal = {IEEE Journal on Emerging and Selected Topics in Circuits and Systems}, edition = {2}, publisher = {IEEE}, address = {New York}, issn = {2156-3357 (Print)}, doi = {10.1109/JETCAS.2023.3278843}, pages = {457 -- 460}, year = {2023}, language = {en} } @inproceedings{HueningMund2023, author = {H{\"u}ning, Felix and Mund, Cindy}, title = {Integration of agile development in standard labs}, series = {51st Annual Conference of the European Society for Engineering Education (SEFI)}, booktitle = {51st Annual Conference of the European Society for Engineering Education (SEFI)}, doi = {10.21427/NK4Z-WS73}, pages = {11 Seiten}, year = {2023}, abstract = {In addition to the technical content, modern courses at university should also teach professional skills to enhance the competencies of students towards their future work. The competency driven approach including technical as well as professional skills makes it necessary to find a suitable way for the integration into the corresponding module in a scalable and flexible manner. Agile development, for example, is essential for the development of modern systems and applications and makes use of dedicated professional skills of the team members, like structured group dynamics and communication, to enable the fast and reliable development. This paper presents an easy to integrate and flexible approach to integrate Scrum, an agile development method, into the lab of an existing module. Due to the different role models of Scrum the students have an individual learning success, gain valuable insight into modern system development and strengthen their communication and organization skills. The approach is implemented and evaluated in the module Vehicle Systems, but it can be transferred easily to other technical courses as well. The evaluation of the implementation considers feedback of all stakeholders, students, supervisor and lecturers, and monitors the observations during project lifetime.}, language = {en} } @article{BruksleChwallekKrastina2023, author = {Bruksle, Ieva and Chwallek, Constanze and Krastina, Anzelika}, title = {Strengthening sustainability in entrepreneurship education - implications for shifting entrepreneurial thinking towards sustainability at universities}, series = {ACTA PROSPERITATIS}, volume = {14}, journal = {ACTA PROSPERITATIS}, number = {1}, publisher = {Sciendo}, issn = {1691-6077}, doi = {10.37804/1691-6077-2023-14-37-48}, pages = {37 -- 48}, year = {2023}, abstract = {By developing innovative solutions to social and environmental problems, sustainable ventures carry greatpotential. Entrepreneurship which focuses especially on new venture creation can be developed through education anduniversities, in particular, are called upon to provide an impetus for social change. But social innovations are associatedwith certain hurdles, which are related to the multi-dimensionality, i.e. the tension between creating social,environmental and economic value and dealing with a multiplicity of stakeholders. The already complex field ofentrepreneurship education has to face these challenges. This paper, therefore, aims to identify starting points for theintegration of sustainability into entrepreneurship education. To pursue this goal experiences from three differentproject initiatives between the partner universities: Lapland University of Applied Sciences, FH Aachen University ofApplied Sciences and Turiba University are reflected and findings are systematically condensed into recommendationsfor education on sustainable entrepreneurship.}, language = {en} } @inproceedings{MaurerMiskiwAcostaetal.2023, author = {Maurer, Florian and Miskiw, Kim K. and Acosta, Rebeca Ramirez and Harder, Nick and Sander, Volker and Lehnhoff, Sebastian}, title = {Market abstraction of energy markets and policies - application in an agent-based modeling toolbox}, series = {EI.A 2023: Energy Informatics}, booktitle = {EI.A 2023: Energy Informatics}, editor = {Jorgensen, Bo Norregaard and Pereira da Silva, Luiz Carlos and Ma, Zheng}, publisher = {Springer}, address = {Cham}, isbn = {978-3-031-48651-7 (Print)}, doi = {10.1007/978-3-031-48652-4_10}, pages = {139 -- 157}, year = {2023}, abstract = {In light of emerging challenges in energy systems, markets are prone to changing dynamics and market design. Simulation models are commonly used to understand the changing dynamics of future electricity markets. However, existing market models were often created with specific use cases in mind, which limits their flexibility and usability. This can impose challenges for using a single model to compare different market designs. This paper introduces a new method of defining market designs for energy market simulations. The proposed concept makes it easy to incorporate different market designs into electricity market models by using relevant parameters derived from analyzing existing simulation tools, morphological categorization and ontologies. These parameters are then used to derive a market abstraction and integrate it into an agent-based simulation framework, allowing for a unified analysis of diverse market designs. Furthermore, we showcase the usability of integrating new types of long-term contracts and over-the-counter trading. To validate this approach, two case studies are demonstrated: a pay-as-clear market and a pay-as-bid long-term market. These examples demonstrate the capabilities of the proposed framework.}, language = {en} } @article{AlnemerKotliarNeuhausetal.2023, author = {Alnemer, Momin Sami Mohammad and Kotliar, Konstantin and Neuhaus, Valentin and Pape, Hans-Christoph and Ciritsis, Bernhard D.}, title = {Cost-effectiveness analysis of surgical proximal femur fracture prevention in elderly: a Markov cohort simulation model}, series = {Cost Effectiveness and Resource Allocation}, journal = {Cost Effectiveness and Resource Allocation}, number = {21, Article number: 77}, publisher = {Springer Nature}, issn = {1478-7547}, doi = {10.1186/s12962-023-00482-4}, pages = {12 Seiten}, year = {2023}, abstract = {Background Hip fractures are a common and costly health problem, resulting in significant morbidity and mortality, as well as high costs for healthcare systems, especially for the elderly. Implementing surgical preventive strategies has the potential to improve the quality of life and reduce the burden on healthcare resources, particularly in the long term. However, there are currently limited guidelines for standardizing hip fracture prophylaxis practices. Methods This study used a cost-effectiveness analysis with a finite-state Markov model and cohort simulation to evaluate the primary and secondary surgical prevention of hip fractures in the elderly. Patients aged 60 to 90 years were simulated in two different models (A and B) to assess prevention at different levels. Model A assumed prophylaxis was performed during the fracture operation on the contralateral side, while Model B included individuals with high fracture risk factors. Costs were obtained from the Centers for Medicare \& Medicaid Services, and transition probabilities and health state utilities were derived from available literature. The baseline assumption was a 10\% reduction in fracture risk after prophylaxis. A sensitivity analysis was also conducted to assess the reliability and variability of the results. Results With a 10\% fracture risk reduction, model A costs between \$8,850 and \$46,940 per quality-adjusted life-year (\$/QALY). Additionally, it proved most cost-effective in the age range between 61 and 81 years. The sensitivity analysis established that a reduction of ≥ 2.8\% is needed for prophylaxis to be definitely cost-effective. The cost-effectiveness at the secondary prevention level was most sensitive to the cost of the contralateral side's prophylaxis, the patient's age, and fracture treatment cost. For high-risk patients with no fracture history, the cost-effectiveness of a preventive strategy depends on their risk profile. In the baseline analysis, the incremental cost-effectiveness ratio at the primary prevention level varied between \$11,000/QALY and \$74,000/QALY, which is below the defined willingness to pay threshold. Conclusion Due to the high cost of hip fracture treatment and its increased morbidity, surgical prophylaxis strategies have demonstrated that they can significantly relieve the healthcare system. Various key assumptions facilitated the modeling, allowing for adequate room for uncertainty. Further research is needed to evaluate health-state-associated risks.}, language = {en} } @article{KuchlerGuenthnerRibeiroetal.2023, author = {Kuchler, Timon and G{\"u}nthner, Roman and Ribeiro, Andrea and Hausinger, Renate and Streese, Lukas and W{\"o}hnl, Anna and Kesseler, Veronika and Negele, Johanna and Assali, Tarek and Carbajo-Lozoya, Javier and Lech, Maciej and Adorjan, Kristina and Stubbe, Hans Christian and Hanssen, Henner and Kotliar, Konstantin and Haller, Berhard and Heemann, Uwe and Schmaderer, Christoph}, title = {Persistent endothelial dysfunction in post-COVID-19 syndrome and its associations with symptom severity and chronic inflammation}, volume = {26}, publisher = {Springer Nature}, address = {Dordrecht}, doi = {10.1007/s10456-023-09885-6}, pages = {547 -- 563}, year = {2023}, abstract = {Background Post-COVID-19 syndrome (PCS) is a lingering disease with ongoing symptoms such as fatigue and cognitive impairment resulting in a high impact on the daily life of patients. Understanding the pathophysiology of PCS is a public health priority, as it still poses a diagnostic and treatment challenge for physicians. Methods In this prospective observational cohort study, we analyzed the retinal microcirculation using Retinal Vessel Analysis (RVA) in a cohort of patients with PCS and compared it to an age- and gender-matched healthy cohort (n = 41, matched out of n = 204). Measurements and main results PCS patients exhibit persistent endothelial dysfunction (ED), as indicated by significantly lower venular flicker-induced dilation (vFID; 3.42\% ± 1.77\% vs. 4.64\% ± 2.59\%; p = 0.02), narrower central retinal artery equivalent (CRAE; 178.1 [167.5-190.2] vs. 189.1 [179.4-197.2], p = 0.01) and lower arteriolar-venular ratio (AVR; (0.84 [0.8-0.9] vs. 0.88 [0.8-0.9], p = 0.007). When combining AVR and vFID, predicted scores reached good ability to discriminate groups (area under the curve: 0.75). Higher PCS severity scores correlated with lower AVR (R = - 0.37 p = 0.017). The association of microvascular changes with PCS severity were amplified in PCS patients exhibiting higher levels of inflammatory parameters. Conclusion Our results demonstrate that prolonged endothelial dysfunction is a hallmark of PCS, and impairments of the microcirculation seem to explain ongoing symptoms in patients. As potential therapies for PCS emerge, RVA parameters may become relevant as clinical biomarkers for diagnosis and therapy management.}, language = {en} } @article{FayyaziSardarThomasetal.2023, author = {Fayyazi, Mojgan and Sardar, Paramjotsingh and Thomas, Sumit Infent and Daghigh, Roonak and Jamali, Ali and Esch, Thomas and Kemper, Hans and Langari, Reza and Khayyam, Hamid}, title = {Artificial intelligence/machine learning in energy management systems, control, and optimization of hydrogen fuel cell vehicles}, volume = {15}, number = {6}, publisher = {MDPI}, address = {Basel}, doi = {10.3390/su15065249}, pages = {38}, year = {2023}, abstract = {Environmental emissions, global warming, and energy-related concerns have accelerated the advancements in conventional vehicles that primarily use internal combustion engines. Among the existing technologies, hydrogen fuel cell electric vehicles and fuel cell hybrid electric vehicles may have minimal contributions to greenhouse gas emissions and thus are the prime choices for environmental concerns. However, energy management in fuel cell electric vehicles and fuel cell hybrid electric vehicles is a major challenge. Appropriate control strategies should be used for effective energy management in these vehicles. On the other hand, there has been significant progress in artificial intelligence, machine learning, and designing data-driven intelligent controllers. These techniques have found much attention within the community, and state-of-the-art energy management technologies have been developed based on them. This manuscript reviews the application of machine learning and intelligent controllers for prediction, control, energy management, and vehicle to everything (V2X) in hydrogen fuel cell vehicles. The effectiveness of data-driven control and optimization systems are investigated to evolve, classify, and compare, and future trends and directions for sustainability are discussed.}, language = {en} } @article{LaarmannThomaMischetal.2023, author = {Laarmann, Lukas and Thoma, Andreas and Misch, Philipp and R{\"o}th, Thilo and Braun, Carsten and Watkins, Simon and Fard, Mohammad}, title = {Automotive safety approach for future eVTOL vehicles}, series = {CEAS Aeronautical Journal}, journal = {CEAS Aeronautical Journal}, publisher = {Springer Nature}, issn = {1869-5590 (Online)}, doi = {10.1007/s13272-023-00655-0}, pages = {11 Seiten}, year = {2023}, abstract = {The eVTOL industry is a rapidly growing mass market expected to start in 2024. eVTOL compete, caused by their predicted missions, with ground-based transportation modes, including mainly passenger cars. Therefore, the automotive and classical aircraft design process is reviewed and compared to highlight advantages for eVTOL development. A special focus is on ergonomic comfort and safety. The need for further investigation of eVTOL's crashworthiness is outlined by, first, specifying the relevance of passive safety via accident statistics and customer perception analysis; second, comparing the current state of regulation and certification; and third, discussing the advantages of integral safety and applying the automotive safety approach for eVTOL development. Integral safety links active and passive safety, while the automotive safety approach means implementing standardized mandatory full-vehicle crash tests for future eVTOL. Subsequently, possible crash impact conditions are analyzed, and three full-vehicle crash load cases are presented.}, language = {en} } @inproceedings{ThomaStiemerBraunetal.2023, author = {Thoma, Andreas and Stiemer, Luc and Braun, Carsten and Fisher, Alex and Gardi, Alessandro G.}, title = {Potential of hybrid neural network local path planner for small UAV in urban environments}, series = {AIAA SCITECH 2023 Forum}, booktitle = {AIAA SCITECH 2023 Forum}, publisher = {AIAA}, address = {Reston, Va.}, doi = {10.2514/6.2023-2359}, pages = {13 Seiten}, year = {2023}, abstract = {This work proposes a hybrid algorithm combining an Artificial Neural Network (ANN) with a conventional local path planner to navigate UAVs efficiently in various unknown urban environments. The proposed method of a Hybrid Artificial Neural Network Avoidance System is called HANNAS. The ANN analyses a video stream and classifies the current environment. This information about the current Environment is used to set several control parameters of a conventional local path planner, the 3DVFH*. The local path planner then plans the path toward a specific goal point based on distance data from a depth camera. We trained and tested a state-of-the-art image segmentation algorithm, PP-LiteSeg. The proposed HANNAS method reaches a failure probability of 17\%, which is less than half the failure probability of the baseline and around half the failure probability of an improved, bio-inspired version of the 3DVFH*. The proposed HANNAS method does not show any disadvantages regarding flight time or flight distance.}, language = {en} } @inproceedings{VladovaUllrichSultanowetal.2023, author = {Vladova, Gergana and Ullrich, Andr{\´e} and Sultanow, Eldar and Tobolla, Marinho and Sebrak, Sebastian and Czarnecki, Christian and Brockmann, Carsten}, title = {Visual analytics for knowledge management}, series = {INFORMATIK 2023 - Designing Futures: Zuk{\"u}nfte gestalten}, booktitle = {INFORMATIK 2023 - Designing Futures: Zuk{\"u}nfte gestalten}, publisher = {GI - Gesellschaft f{\"u}r Informatik}, address = {Bonn}, isbn = {978-3-88579-731-9}, issn = {1617-5468}, doi = {10.18420/inf2023_187}, pages = {1851 -- 1870}, year = {2023}, abstract = {The management of knowledge in organizations considers both established long-term processes and cooperation in agile project teams. Since knowledge can be both tacit and explicit, its transfer from the individual to the organizational knowledge base poses a challenge in organizations. This challenge increases when the fluctuation of knowledge carriers is exceptionally high. Especially in large projects in which external consultants are involved, there is a risk that critical, company-relevant knowledge generated in the project will leave the company with the external knowledge carrier and thus be lost. In this paper, we show the advantages of an early warning system for knowledge management to avoid this loss. In particular, the potential of visual analytics in the context of knowledge management systems is presented and discussed. We present a project for the development of a business-critical software system and discuss the first implementations and results.}, language = {en} } @incollection{SchultLosseCzarneckietal.2023, author = {Schult, Prince Garcia and Losse, Ann-Kathrin and Czarnecki, Christian and Sultanow, Eldar}, title = {Proposing a Framework to address the Sustainable Development Goals}, series = {EnviroInfo 2023}, booktitle = {EnviroInfo 2023}, publisher = {GI - Gesellschaft f{\"u}r Informatik}, address = {Bonn}, isbn = {978-3-88579-736-4}, issn = {1617-5468}, doi = {10.18420/env2023-022}, pages = {243 -- 249}, year = {2023}, abstract = {Reducing poverty, protecting the planet, and improving life on earth for everyone are the essential goals of the "2030 Agenda for Sustainable Development"committed by the United Nations (UN). Achieving those goals will require technological innovation as well as their implementation in almost all areas of our business and day-to-day life. This paper proposes a high-level framework that collects and structures different uses cases addressing the goals defined by the UN. Hence, it contributes to the discussion by proposing technical innovations that can be used to achieve those goals. As an example, the goal "Climate Action{\"i}s discussed in detail by describing use cases related to tackling biodiversity loss in order to conservate ecosystems.}, language = {en} } @article{MuesgenanntKoersMcNeilRadchenkoetal.2023, author = {Mues genannt Koers, Lucas and McNeil, S. W. and Radchenko, V. and Paulßen, Elisabeth and Hoehr, Cornelia}, title = {Production of Co-58m in a siphon-style liquid target on a medical cyclotron}, volume = {195}, number = {Art. 110734}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0969-8043}, doi = {10.1016/j.apradiso.2023.110734}, year = {2023}, abstract = {We present the production of 58mCo on a small, 13 MeV medical cyclotron utilizing a siphon style liquid target system. Different concentrated iron(III)-nitrate solutions of natural isotopic distribution were irradiated at varying initial pressures and subsequently separated by solid phase extraction chromatography. The radio cobalt (58m/gCo and 56Co) was successfully produced with saturation activities of (0.35 ± 0.03) MBq μA-1 for 58mCo with a separation recovery of (75 ± 2) \% of cobalt after one separation step utilizing LN-resin.}, language = {en} } @article{MuesgenanntKoersPrevostPaulssenetal.2023, author = {Mues genannt Koers, Lucas and Prevost, David and Paulßen, Elisabeth and Hoehr, Cornelia}, title = {Density reduction effects on the production of [11C]CO2 in Nb-body targets on a medical cyclotron}, volume = {199}, number = {Art. 110911}, publisher = {Elsevier}, address = {Amsterdam}, doi = {10.1016/j.apradiso.2023.110911}, year = {2023}, abstract = {Medical isotope production of 11C is commonly performed in gaseous targets. The power deposition of the proton beam during the irradiation decreases the target density due to thermodynamic mixing and can cause an increase of penetration depth and divergence of the proton beam. In order to investigate the difference how the target-body length influences the operation conditions and the production yield, a 12 cm and a 22 cm Nb-target body containing N2/O2 gas were irradiated using a 13 MeV proton cyclotron. It was found that the density reduction has a large influence on the pressure rise during irradiation and the achievable radioactive yield. The saturation activity of [11C]CO2 for the long target (0.083 Ci/μA) is about 10\% higher than in the short target geometry (0.075 Ci/μA).}, language = {en} } @article{DroopChenRadfordetal.2023, author = {Droop, Philipp and Chen, Shaohuang and Radford, Melissa J. and Paulßen, Elisabeth and Gates, Byron D. and Reilly, Raymond M. and Radchenko, Valery and Hoehr, Cornelia}, title = {Synthesis of 197m/gHg labelled gold nanoparticles for targeted radionuclide therapy}, series = {Radiochimica Acta}, volume = {111}, journal = {Radiochimica Acta}, number = {10}, publisher = {De Gruyter}, address = {Berlin [u.a.]}, issn = {2193-3405}, doi = {10.1515/ract-2023-0144}, pages = {773 -- 779}, year = {2023}, abstract = {Meitner-Auger-electron emitters have a promising potential for targeted radionuclide therapy of cancer because of their short range and the high linear energy transfer of Meitner-Auger-electrons (MAE). One promising MAE candidate is 197m/gHg with its half-life of 23.8 h and 64.1 h, respectively, and high MAE yield. Gold nanoparticles (AuNPs) that are labelled with 197m/gHg could be a helpful tool for radiation treatment of glioblastoma multiforme when infused into the surgical cavity after resection to prevent recurrence. To produce such AuNPs, 197m/gHg was embedded into pristine AuNPs. Two different syntheses were tested starting from irradiated gold containing trace amounts of 197m/gHg. When sodium citrate was used as reducing agent, no 197m/gHg labelled AuNPs were formed, but with tannic acid, 197m/gHg labeled AuNPs were produced. The method was optimized by neutralizing the pH (pH = 7) of the Au/197m/gHg solution, which led to labelled AuNPs with a size of 12.3 ± 2.0 nm as measured by transmission electron microscopy. The labelled AuNPs had a concentration of 50 μg (gold)/mL with an activity of 151 ± 93 kBq/mL (197gHg, time corrected to the end of bombardment).}, language = {en} } @article{UlmerBraunChengetal.2023, author = {Ulmer, Jessica and Braun, Sebastian and Cheng, Chi-Tsun and Dowey, Steve and Wollert, J{\"o}rg}, title = {A human factors-aware assistance system in manufacturing based on gamification and hardware modularisation}, series = {International Journal of Production Research}, journal = {International Journal of Production Research}, publisher = {Taylor \& Francis}, issn = {0020-7543 (Print)}, doi = {10.1080/00207543.2023.2166140}, year = {2023}, abstract = {Assistance systems have been widely adopted in the manufacturing sector to facilitate various processes and tasks in production environments. However, existing systems are mostly equipped with rigid functional logic and do not provide individual user experiences or adapt to their capabilities. This work integrates human factors in assistance systems by adjusting the hardware and instruction presented to the workers' cognitive and physical demands. A modular system architecture is designed accordingly, which allows a flexible component exchange according to the user and the work task. Gamification, the use of game elements in non-gaming contexts, has been further adopted in this work to provide level-based instructions and personalised feedback. The developed framework is validated by applying it to a manual workstation for industrial assembly routines.}, language = {en} } @inproceedings{MulsowHuelsenGuetzlaffetal.2023, author = {Mulsow, Niklas A. and H{\"u}lsen, Benjamin and G{\"u}tzlaff, Joel and Spies, Leon and Bresser, Andreas and Dabrowski, Adam and Czupalla, Markus and Kirchner, Frank}, title = {Concept and design of an autonomous micro rover for long term lunar exploration}, series = {Proceedings of the 74th International Astronautical Congress}, booktitle = {Proceedings of the 74th International Astronautical Congress}, publisher = {dfki}, address = {Saarbr{\"u}cken}, pages = {13 Seiten}, year = {2023}, abstract = {Research on robotic lunar exploration has seen a broad revival, especially since the Google Lunar X-Prize increasingly brought private endeavors into play. This development is supported by national agencies with the aim of enabling long-term lunar infrastructure for in-situ operations and the establishment of a moon village. One challenge for effective exploration missions is developing a compact and lightweight robotic rover to reduce launch costs and open the possibility for secondary payload options. Existing micro rovers for exploration missions are clearly limited by their design for one day of sunlight and their low level of autonomy. For expanding the potential mission applications and range of use, an extension of lifetime could be reached by surviving the lunar night and providing a higher level of autonomy. To address this objective, the paper presents a system design concept for a lightweight micro rover with long-term mission duration capabilities, derived from a multi-day lunar mission scenario at equatorial regions. Technical solution approaches are described, analyzed, and evaluated, with emphasis put on the harmonization of hardware selection due to a strictly limited budget in dimensions and power.}, language = {en} } @inproceedings{HuelsenMulsowDabrowskietal.2023, author = {H{\"u}lsen, Benjamin and Mulsow, Niklas A. and Dabrowski, Adam and Brinkmann, Wiebke and G{\"u}tzlaff, Joel and Spies, Leon and Czupalla, Markus and Kirchner, Frank}, title = {Towards an autonomous micro rover with night survivability for lunar exploration}, series = {Proceedings of the 74th International Astronautical Congress}, booktitle = {Proceedings of the 74th International Astronautical Congress}, publisher = {dfki}, pages = {12 Seiten}, year = {2023}, abstract = {In Europe, efforts are underway to develop key technologies that can be used to explore the Moon and to exploit the resources available. This includes technologies for in-situ resource utilization (ISRU), facilitating the possibility of a future Moon Village. The Moon is the next step for humans and robots to exploit the use of available resources for longer term missions, but also for further exploration of the solar system. A challenge for effective exploration missions is to achieve a compact and lightweight robot to reduce launch costs and open up the possibility of secondary payload options. Current micro rover concepts are primarily designed to last for one day of solar illumination and show a low level of autonomy. Extending the lifetime of the system by enabling survival of the lunar night and implementing a high level of autonomy will significantly increase potential mission applications and the operational range. As a reference mission, the deployment of a micro rover in the equatorial region of the Moon is being considered. An overview of mission parameters and a detailed example mission sequence is given in this paper. The mission parameters are based on an in-depth study of current space agency roadmaps, scientific goals, and upcoming flight opportunities. Furthermore, concepts of the ongoing international micro rover developments are analyzed along with technology solutions identified for survival of lunar nights and a high system autonomy. The results provide a basis of a concise requirements set-up to allow dedicated system developments and qualification measures in the future.}, language = {en} }