@book{ButenwegHoffmeisterHoltschoppenetal.2020, author = {Butenweg, Christoph and Hoffmeister, Benno and Holtschoppen, Britta and Klinkel, Sven and Rosin, Julia and Schmitt, Timo}, title = {Seismic design of industrial facilities 2020: proceedings of the 2nd International Conference on Seismic Design of Industrial Facilities (SeDIF-Conference)}, publisher = {Apprimus Verlag}, address = {Aachen}, isbn = {978-3-86359-729-0}, pages = {524 Seiten}, year = {2020}, language = {en} } @inproceedings{RekePeterSchulteTiggesetal.2020, author = {Reke, Michael and Peter, Daniel and Schulte-Tigges, Joschua and Schiffer, Stefan and Ferrein, Alexander and Walter, Thomas and Matheis, Dominik}, title = {A Self-Driving Car Architecture in ROS2}, series = {2020 International SAUPEC/RobMech/PRASA Conference, Cape Town, South Africa}, booktitle = {2020 International SAUPEC/RobMech/PRASA Conference, Cape Town, South Africa}, publisher = {IEEE}, address = {New York, NY}, isbn = {978-1-7281-4162-6}, doi = {10.1109/SAUPEC/RobMech/PRASA48453.2020.9041020}, pages = {1 -- 6}, year = {2020}, abstract = {In this paper we report on an architecture for a self-driving car that is based on ROS2. Self-driving cars have to take decisions based on their sensory input in real-time, providing high reliability with a strong demand in functional safety. In principle, self-driving cars are robots. However, typical robot software, in general, and the previous version of the Robot Operating System (ROS), in particular, does not always meet these requirements. With the successor ROS2 the situation has changed and it might be considered as a solution for automated and autonomous driving. Existing robotic software based on ROS was not ready for safety critical applications like self-driving cars. We propose an architecture for using ROS2 for a self-driving car that enables safe and reliable real-time behaviour, but keeping the advantages of ROS such as a distributed architecture and standardised message types. First experiments with an automated real passenger car at lower and higher speed-levels show that our approach seems feasible for autonomous driving under the necessary real-time conditions.}, language = {en} } @inproceedings{OetringerDuemmlerGoettsche2020, author = {Oetringer, Kerstin and D{\"u}mmler, Andreas and G{\"o}ttsche, Joachim}, title = {Neues Modell zur 1D-Simulation der indirekten Verdunstungsk{\"u}hlung}, series = {DKV-Tagung 2020, AA II.1}, booktitle = {DKV-Tagung 2020, AA II.1}, pages = {250 -- 262}, year = {2020}, abstract = {Im Projekt Coolplan- AIR geht es um die Fortentwicklung und Feld- Validierung eines Berechnungs- und Auslegungstools zur energieeffizienten K{\"u}hlung von Geb{\"a}uden mit luftgest{\"u}tzten Systemen. Neben dem Aufbau und der Weiterentwicklung von Simulationsmodellen erfolgen Vermessungen der Gesamtsysteme anhand von Praxisanlagen im Feld. Eine der betrachteten Anlagen arbeitet mit indirekter Verdunstung. Diese Ver{\"o}ffentlichung zeigt den Entwicklungsprozess und den Aufbau des Simulationsmodells zur Verdunstungsk{\"u}hlung in der Simulationsumgebung Matlab- Simulink mit der CARNOT- Toolbox. Das besondere Augenmerk liegt dabei auf dem physikalischen Modell des W{\"a}rme{\"u}bertragers, in dem die Verdunstung implementiert ist. Dem neuen Modellansatz liegt die Annahme einer aus der Enthalpie- Betrachtung hergeleiteten effektiven W{\"a}rmekapazit{\"a}t zugrunde. Des Weiteren wird der Befeuchtungsgrad als konstant angesehen und eine standardisierte Zunahme der W{\"a}rme{\"u}bertragung des feuchten gegen{\"u}ber dem trockenen W{\"a}rme{\"u}bertrager angenommen. Die Validierung des Modells erfolgte anhand von Literaturdaten. F{\"u}r den trockenen W{\"a}rmetauscher ist der maximale absolute Fehler der berechneten Austrittstemperatur (Zuluft) kleiner als ±0.1 K und f{\"u}r den nassen W{\"a}rmetauscher (K{\"u}hlfall) unter der Annahme eines konstanten Verdunstungsgrades kleiner als ±0.4 K.}, language = {de} } @incollection{GollandOhrtmann2020, author = {Golland, Alexander and Ohrtmann, Jan-Peter}, title = {Video surveillance: The supervisory authorities' view andrecent case law}, series = {Turning Point in Data Protection Law}, booktitle = {Turning Point in Data Protection Law}, publisher = {Nomos}, address = {Baden-Baden}, isbn = {978-3-8487-6909-4}, doi = {10.5771/9783748921561-175}, pages = {175 -- 178}, year = {2020}, language = {en} } @article{Stulpe2020, author = {Stulpe, Werner}, title = {Pairwise coexistence of effects versus coexistence}, series = {Journal of Physics: Conference Series}, volume = {1638}, journal = {Journal of Physics: Conference Series}, number = {012004}, publisher = {IOP}, address = {Bristol}, issn = {1742-6596}, doi = {10.1088/1742-6596/1638/1/012004}, pages = {1 -- 21}, year = {2020}, language = {en} } @inproceedings{SattlerChicoCaminosUerlingsetal.2020, author = {Sattler, Johannes Christoph and Chico Caminos, Ricardo Alexander and {\"U}rlings, Nicolas and Dutta, Siddharth and Ruiz, Victor and Kalogirou, Soteris and Ktistis, Panayiotis and Agathokleous, Rafaela and Jung, Christian and Alexopoulos, Spiros and Atti, Vikrama Nagababu and Teixeira Boura, Cristiano Jos{\´e} and Herrmann, Ulf}, title = {Operational experience and behaviour of a parabolic trough collector system with concrete thermal energy storage for process steam generation in Cyprus}, series = {AIP Conference Proceedings}, booktitle = {AIP Conference Proceedings}, number = {2303}, doi = {10.1063/5.0029278}, pages = {140004-1 -- 140004-10}, year = {2020}, abstract = {As part of the transnational research project EDITOR, a parabolic trough collector system (PTC) with concrete thermal energy storage (C-TES) was installed and commissioned in Limassol, Cyprus. The system is located on the premises of the beverage manufacturer KEAN Soft Drinks Ltd. and its function is to supply process steam for the factory's pasteurisation process [1]. Depending on the factory's seasonally varying capacity for beverage production, the solar system delivers between 5 and 25 \% of the total steam demand. In combination with the C-TES, the solar plant can supply process steam on demand before sunrise or after sunset. Furthermore, the C-TES compensates the PTC during the day in fluctuating weather conditions. The parabolic trough collector as well as the control and oil handling unit is designed and manufactured by Protarget AG, Germany. The C-TES is designed and produced by CADE Soluciones de Ingenier{\´i}a, S.L., Spain. In the focus of this paper is the description of the operational experience with the PTC, C-TES and boiler during the commissioning and operation phase. Additionally, innovative optimisation measures are presented.}, language = {en} } @article{GossmannThomasHorvathetal.2020, author = {Gossmann, Matthias and Thomas, Ulrich and Horv{\´a}th, Andr{\´a}s and Dragicevic, Elena and Stoelzle-Feix, Sonja and Jung, Alexander and Raman, Aravind Hariharan and Staat, Manfred and Linder, Peter}, title = {A higher-throughput approach to investigate cardiac contractility in vitro under physiological mechanical conditions}, series = {Journal of Pharmacological and Toxicological Methods}, volume = {105}, journal = {Journal of Pharmacological and Toxicological Methods}, number = {Article 106843}, publisher = {Elsevier}, address = {New York, NY}, doi = {10.1016/j.vascn.2020.106843}, year = {2020}, language = {en} } @article{SattlerRoegerSchwarzboezletal.2020, author = {Sattler, Johannes Christoph and R{\"o}ger, Marc and Schwarzb{\"o}zl, Peter and Buck, Reiner and Macke, Ansgar and Raeder, Christian and G{\"o}ttsche, Joachim}, title = {Review of heliostat calibration and tracking control methods}, series = {Solar Energy}, volume = {207}, journal = {Solar Energy}, publisher = {Elsevier}, address = {Amsterdam}, doi = {10.1016/j.solener.2020.06.030}, pages = {110 -- 132}, year = {2020}, abstract = {Large scale central receiver systems typically deploy between thousands to more than a hundred thousand heliostats. During solar operation, each heliostat is aligned individually in such a way that the overall surface normal bisects the angle between the sun's position and the aim point coordinate on the receiver. Due to various tracking error sources, achieving accurate alignment ≤1 mrad for all the heliostats with respect to the aim points on the receiver without a calibration system can be regarded as unrealistic. Therefore, a calibration system is necessary not only to improve the aiming accuracy for achieving desired flux distributions but also to reduce or eliminate spillage. An overview of current larger-scale central receiver systems (CRS), tracking error sources and the basic requirements of an ideal calibration system is presented. Leading up to the main topic, a description of general and specific terms on the topics heliostat calibration and tracking control clarifies the terminology used in this work. Various figures illustrate the signal flows along various typical components as well as the corresponding monitoring or measuring devices that indicate or measure along the signal (or effect) chain. The numerous calibration systems are described in detail and classified in groups. Two tables allow the juxtaposition of the calibration methods for a better comparison. In an assessment, the advantages and disadvantages of individual calibration methods are presented.}, language = {en} } @inproceedings{Laack2020, author = {Laack, Walter van}, title = {Schnittstelle Tod: Aufbruch oder Ende - Kontakte oder Hirngespinste?}, publisher = {van Laack GmbH}, address = {Aachen}, isbn = {978-3-936624-51-9}, pages = {264 Seiten}, year = {2020}, abstract = {Tagungsbeitr{\"a}ge des 6. Europ{\"a}ischen Seminars am 09. November 2019 in Aachen zum Thema Nahtoderfahrungen mit dem Serientitel: "Schnittstelle Tod"}, language = {de} } @misc{OhrtmannGolland2020, author = {Ohrtmann, Jan-Peter and Golland, Alexander}, title = {Daten- und Privatsph{\"a}reschutz im Wandel der 2020er-Jahre}, pages = {33 -- 38}, year = {2020}, language = {de} } @article{FingerGoettenBraunetal.2020, author = {Finger, Felix and G{\"o}tten, Falk and Braun, Carsten and Bil, Cees}, title = {Mass, primary energy, and cost: the impact of optimization objectives on the initial sizing of hybrid-electric general aviation aircraft}, series = {CEAS Aeronautical Journal}, volume = {2020}, journal = {CEAS Aeronautical Journal}, number = {11}, publisher = {Springer}, address = {Heidelberg}, issn = {1869-5590}, doi = {10.1007/s13272-020-00449-8}, pages = {713 -- 730}, year = {2020}, abstract = {For short take-off and landing (STOL) aircraft, a parallel hybrid-electric propulsion system potentially offers superior performance compared to a conventional propulsion system, because the short-take-off power requirement is much higher than the cruise power requirement. This power-matching problem can be solved with a balanced hybrid propulsion system. However, there is a trade-off between wing loading, power loading, the level of hybridization, as well as range and take-off distance. An optimization method can vary design variables in such a way that a minimum of a particular objective is attained. In this paper, a comparison between the optimization results for minimum mass, minimum consumed primary energy, and minimum cost is conducted. A new initial sizing algorithm for general aviation aircraft with hybrid-electric propulsion systems is applied. This initial sizing methodology covers point performance, mission performance analysis, the weight estimation process, and cost estimation. The methodology is applied to the design of a STOL general aviation aircraft, intended for on-demand air mobility operations. The aircraft is sized to carry eight passengers over a distance of 500 km, while able to take off and land from short airstrips. Results indicate that parallel hybrid-electric propulsion systems must be considered for future STOL aircraft.}, language = {en} } @article{TranStaat2020, author = {Tran, Ngoc Trinh and Staat, Manfred}, title = {Direct plastic structural design under lognormally distributed strength by chance constrained programming}, series = {Optimization and Engineering}, volume = {21}, journal = {Optimization and Engineering}, number = {1}, publisher = {Springer Nature}, address = {Cham}, issn = {1573-2924}, doi = {10.1007/s11081-019-09437-2}, pages = {131 -- 157}, year = {2020}, abstract = {We propose the so-called chance constrained programming model of stochastic programming theory to analyze limit and shakedown loads of structures under random strength with a lognormal distribution. A dual chance constrained programming algorithm is developed to calculate simultaneously both the upper and lower bounds of the plastic collapse limit and the shakedown limit. The edge-based smoothed finite element method (ES-FEM) is used with three-node linear triangular elements.}, language = {en} } @article{PoghossianSchoening2020, author = {Poghossian, Arshak and Sch{\"o}ning, Michael Josef}, title = {Capacitive field-effect eis chemical sensors and biosensors: A status report}, series = {Sensors}, volume = {20}, journal = {Sensors}, number = {19}, publisher = {MDPI}, address = {Basel}, issn = {1424-8220}, doi = {10.3390/s20195639}, pages = {Artikel 5639}, year = {2020}, abstract = {Electrolyte-insulator-semiconductor (EIS) field-effect sensors belong to a new generation of electronic chips for biochemical sensing, enabling a direct electronic readout. The review gives an overview on recent advances and current trends in the research and development of chemical sensors and biosensors based on the capacitive field-effect EIS structure—the simplest field-effect device, which represents a biochemically sensitive capacitor. Fundamental concepts, physicochemical phenomena underlying the transduction mechanism and application of capacitive EIS sensors for the detection of pH, ion concentrations, and enzymatic reactions, as well as the label-free detection of charged molecules (nucleic acids, proteins, and polyelectrolytes) and nanoparticles, are presented and discussed.}, language = {en} } @article{DrummEmhardtKoketal.2020, author = {Drumm, Christian and Emhardt, Selina N. and Kok, Ellen M. and Jarodzka, Halzka and Brand-Gruwel, Saskia and van Gog, Tamara}, title = {How Experts Adapt Their Gaze Behavior When Modeling a Task to Novices}, series = {Cognitive science}, volume = {44}, journal = {Cognitive science}, number = {9}, publisher = {Wiley}, address = {Weinheim}, issn = {1551-6709}, doi = {10.1111/cogs.12893}, pages = {26}, year = {2020}, abstract = {Domain experts regularly teach novice students how to perform a task. This often requires them to adjust their behavior to the less knowledgeable audience and, hence, to behave in a more didactic manner. Eye movement modeling examples (EMMEs) are a contemporary educational tool for displaying experts' (natural or didactic) problem-solving behavior as well as their eye movements to learners. While research on expert-novice communication mainly focused on experts' changes in explicit, verbal communication behavior, it is as yet unclear whether and how exactly experts adjust their nonverbal behavior. This study first investigated whether and how experts change their eye movements and mouse clicks (that are displayed in EMMEs) when they perform a task naturally versus teach a task didactically. Programming experts and novices initially debugged short computer codes in a natural manner. We first characterized experts' natural problem-solving behavior by contrasting it with that of novices. Then, we explored the changes in experts' behavior when being subsequently instructed to model their task solution didactically. Experts became more similar to novices on measures associated with experts' automatized processes (i.e., shorter fixation durations, fewer transitions between code and output per click on the run button when behaving didactically). This adaptation might make it easier for novices to follow or imitate the expert behavior. In contrast, experts became less similar to novices for measures associated with more strategic behavior (i.e., code reading linearity, clicks on run button) when behaving didactically.}, language = {en} } @article{RoepkeKoehlerDruryetal.2020, author = {Roepke, Rene and K{\"o}hler, Klemens and Drury, Vincent and Schroeder, Ulrik and Wolf, Martin R. and Meyer, Ulrike}, title = {A pond full of phishing games - analysis of learning games for anti-phishing education}, series = {Model-driven Simulation and Training Environments for Cybersecurity. MSTEC 2020}, journal = {Model-driven Simulation and Training Environments for Cybersecurity. MSTEC 2020}, publisher = {Springer}, address = {Cham}, isbn = {978-3-030-62433-0}, doi = {10.1007/978-3-030-62433-0_32020}, pages = {41 -- 60}, year = {2020}, abstract = {Game-based learning is a promising approach to anti-phishing education, as it fosters motivation and can help reduce the perceived difficulty of the educational material. Over the years, several prototypes for game-based applications have been proposed, that follow different approaches in content selection, presentation, and game mechanics. In this paper, a literature and product review of existing learning games is presented. Based on research papers and accessible applications, an in-depth analysis was conducted, encompassing target groups, educational contexts, learning goals based on Bloom's Revised Taxonomy, and learning content. As a result of this review, we created the publications on games (POG) data set for the domain of anti-phishing education. While there are games that can convey factual and conceptual knowledge, we find that most games are either unavailable, fail to convey procedural knowledge or lack technical depth. Thus, we identify potential areas of improvement for games suitable for end-users in informal learning contexts.}, language = {en} } @article{FingerBraunBil2020, author = {Finger, Felix and Braun, Carsten and Bil, Cees}, title = {Impact of Battery Performance on the Initial Sizing of Hybrid-Electric General Aviation Aircraft}, series = {Journal of Aerospace Engineering}, volume = {33}, journal = {Journal of Aerospace Engineering}, number = {3}, publisher = {ASCE}, address = {Reston, Va.}, issn = {1943-5525}, doi = {10.1061/(ASCE)AS.1943-5525.0001113}, year = {2020}, abstract = {Studies suggest that hybrid-electric aircraft have the potential to generate fewer emissions and be inherently quieter when compared to conventional aircraft. By operating combustion engines together with an electric propulsion system, synergistic benefits can be obtained. However, the performance of hybrid-electric aircraft is still constrained by a battery's energy density and discharge rate. In this paper, the influence of battery performance on the gross mass for a four-seat general aviation aircraft with a hybrid-electric propulsion system is analyzed. For this design study, a high-level approach is chosen, using an innovative initial sizing methodology to determine the minimum required aircraft mass for a specific set of requirements and constraints. Only the peak-load shaving operational strategy is analyzed. Both parallel- and serial-hybrid propulsion configurations are considered for two different missions. The specific energy of the battery pack is varied from 200 to 1,000 W⋅h/kg, while the discharge time, and thus the normalized discharge rating (C-rating), is varied between 30 min (2C discharge rate) and 2 min (30C discharge rate). With the peak-load shaving operating strategy, it is desirable for hybrid-electric aircraft to use a light, low capacity battery system to boost performance. For this case, the battery's specific power rating proved to be of much higher importance than for full electric designs, which have high capacity batteries. Discharge ratings of 20C allow a significant take-off mass reduction aircraft. The design point moves to higher wing loadings and higher levels of hybridization if batteries with advanced technology are used.}, language = {en} } @book{Heuermann2020, author = {Heuermann, Holger}, title = {Mikrowellentechnik: Feldsimulation, nichtlineare Schaltungstechnik, Komponenten und Subsysteme, Plasmatechnik, Antennen und Ausbreitung}, publisher = {Springer Vieweg}, address = {Wiesbaden}, isbn = {978-3-658-29023-8 (eBook)}, doi = {10.1007/978-3-658-29023-8}, pages = {Online-Ressource (XIV, 385 S. 374 Abb., 22 Abb. in Farbe)}, year = {2020}, language = {de} } @article{EggertMoulen2020, author = {Eggert, Mathias and Moulen, Tobias}, title = {Selektion von Gesch{\"a}ftsprozessen zur Anwendung von Robotic Process Automation am Beispiel einer Versicherung}, series = {HMD Praxis der Wirtschaftsinformatik}, volume = {57}, journal = {HMD Praxis der Wirtschaftsinformatik}, number = {6}, publisher = {Springer}, address = {Weinheim}, issn = {1436-3011}, doi = {10.1365/s40702-020-00665-0}, pages = {1150 -- 1162}, year = {2020}, abstract = {H{\"a}ufig bremsen geringe IT-Ressourcen, fehlende Softwareschnittstellen oder eine veraltete und komplex gewachsene Systemlandschaft die Automatisierung von Gesch{\"a}ftsprozessen. Robotic Process Automation (RPA) ist eine vielversprechende Methode, um Gesch{\"a}ftsprozesse oberfl{\"a}chenbasiert und ohne gr{\"o}ßere Systemeingriffe zu automatisieren und Medienbr{\"u}che abzubauen. Die Auswahl der passenden Prozesse ist dabei f{\"u}r den Erfolg von RPA-Projekten entscheidend. Der vorliegende Beitrag liefert daf{\"u}r Selektionskriterien, die aus einer qualitativen Inhaltanalyse von elf Interviews mit RPA-Experten aus dem Versicherungsumfeld resultieren. Das Ergebnis umfasst eine gewichtetet Liste von sieben Dimensionen und 51 Prozesskriterien, welche die Automatisierung mit Softwarerobotern beg{\"u}nstigen bzw. deren Nichterf{\"u}llung eine Umsetzung erschweren oder sogar verhindern. Die drei wichtigsten Kriterien zur Auswahl von Gesch{\"a}ftsprozessen f{\"u}r die Automatisierung mittels RPA umfassen die Entlastung der an dem Prozess mitwirkenden Mitarbeiter (Arbeitnehmer{\"u}berlastung), die Ausf{\"u}hrbarkeit des Prozesses mittels Regeln (Regelbasierte Prozessteuerung) sowie ein positiver Kosten-Nutzen-Vergleich. Praktiker k{\"o}nnen diese Kriterien verwenden, um eine systematische Auswahl von RPA-relevanten Prozessen vorzunehmen. Aus wissenschaftlicher Perspektive stellen die Ergebnisse eine Grundlage zur Erkl{\"a}rung des Erfolgs und Misserfolgs von RPA-Projekten dar.}, language = {de} } @article{Golland2020, author = {Golland, Alexander}, title = {Die „private" Datenverarbeitung im Internet. Verantwortlichkeiten und Rechtm{\"a}ßigkeit bei Nutzung von Plattformdiensten durch nat{\"u}rliche Personen}, series = {ZD Zeitschrift f{\"u}r Datenschutz}, volume = {10}, journal = {ZD Zeitschrift f{\"u}r Datenschutz}, number = {8}, editor = {Hoeren, Thomas and Schneider, Jochen and Selmayr, Martin and Spies, Axel and Wybitul, Tim}, publisher = {Beck}, address = {M{\"u}nchen}, isbn = {2192-5593}, pages = {397 -- 403}, year = {2020}, language = {de} } @inproceedings{EltesterFerreinSchiffer2020, author = {Eltester, Niklas Sebastian and Ferrein, Alexander and Schiffer, Stefan}, title = {A smart factory setup based on the RoboCup logistics league}, series = {2020 IEEE Conference on Industrial Cyberphysical Systems (ICPS)}, booktitle = {2020 IEEE Conference on Industrial Cyberphysical Systems (ICPS)}, publisher = {IEEE}, address = {New York, NY}, doi = {10.1109/ICPS48405.2020.9274766}, pages = {297 -- 302}, year = {2020}, abstract = {In this paper we present SMART-FACTORY, a setup for a research and teaching facility in industrial robotics that is based on the RoboCup Logistics League. It is driven by the need for developing and applying solutions for digital production. Digitization receives constantly increasing attention in many areas, especially in industry. The common theme is to make things smart by using intelligent computer technology. Especially in the last decade there have been many attempts to improve existing processes in factories, for example, in production logistics, also with deploying cyber-physical systems. An initiative that explores challenges and opportunities for robots in such a setting is the RoboCup Logistics League. Since its foundation in 2012 it is an international effort for research and education in an intra-warehouse logistics scenario. During seven years of competition a lot of knowledge and experience regarding autonomous robots was gained. This knowledge and experience shall provide the basis for further research in challenges of future production. The focus of our SMART-FACTORY is to create a stimulating environment for research on logistics robotics, for teaching activities in computer science and electrical engineering programmes as well as for industrial users to study and explore the feasibility of future technologies. Building on a very successful history in the RoboCup Logistics League we aim to provide stakeholders with a dedicated facility oriented at their individual needs.}, language = {en} } @incollection{Laack2020, author = {Laack, Walter van}, title = {Twee Kanten van {\´e}{\´e}n Medaille}, series = {Het Geheim van Elysion : 45 Jaar Studies naar Nabij-de-Dood-Ervaringen over Bewustzijn in Liefde zonder Waarheen}, booktitle = {Het Geheim van Elysion : 45 Jaar Studies naar Nabij-de-Dood-Ervaringen over Bewustzijn in Liefde zonder Waarheen}, publisher = {Van Warven}, address = {Kampen}, isbn = {978-94-93175-44-0}, pages = {97 -- 105}, year = {2020}, language = {nl} } @book{LohseLaumannWolf2020, author = {Lohse, Wolfram and Laumann, J{\"o}rg and Wolf, Christian}, title = {Stahlbau 2}, edition = {21., vollst. akt. und {\"u}berarb. Aufl.}, publisher = {Springer Vieweg}, address = {Wiesbaden}, isbn = {978-3-8348-2116-4}, doi = {10.1007/978-3-8348-2116-4}, year = {2020}, language = {de} } @article{BreussKleefeld2020, author = {Breuß, Michael and Kleefeld, Andreas}, title = {Implicit monotone difference methods for scalar conservation laws with source terms}, series = {Acta Mathematica Vietnamica}, volume = {45}, journal = {Acta Mathematica Vietnamica}, publisher = {Springer Singapore}, address = {Singapore}, issn = {2315-4144}, doi = {10.1007/s40306-019-00354-1}, pages = {709 -- 738}, year = {2020}, abstract = {In this article, a concept of implicit methods for scalar conservation laws in one or more spatial dimensions allowing also for source terms of various types is presented. This material is a significant extension of previous work of the first author (Breuß SIAM J. Numer. Anal. 43(3), 970-986 2005). Implicit notions are developed that are centered around a monotonicity criterion. We demonstrate a connection between a numerical scheme and a discrete entropy inequality, which is based on a classical approach by Crandall and Majda. Additionally, three implicit methods are investigated using the developed notions. Next, we conduct a convergence proof which is not based on a classical compactness argument. Finally, the theoretical results are confirmed by various numerical tests.}, language = {en} } @misc{Golland2020, author = {Golland, Alexander}, title = {Anspruch gegen einen Suchmaschinenbetreiber auf L{\"o}schung von Suchergebnissen}, series = {ZD Zeitschrift f{\"u}r Datenschutz}, volume = {2020}, journal = {ZD Zeitschrift f{\"u}r Datenschutz}, number = {10}, publisher = {Beck}, address = {M{\"u}nchen}, issn = {2192-5593}, pages = {531 -- 532}, year = {2020}, language = {de} } @article{Golland2020, author = {Golland, Alexander}, title = {Weckruf f{\"u}r deutsche Großunternehmen? - Der neue Entwurf des IT-Sicherheitsgesetz 2.0}, series = {K\&R Kommunikation \& Recht}, volume = {23}, journal = {K\&R Kommunikation \& Recht}, number = {7-8}, publisher = {DFV Mediengruppe}, address = {Frankfurt a.M.}, isbn = {1434-6354}, pages = {I}, year = {2020}, language = {de} } @misc{Golland2020, author = {Golland, Alexander}, title = {Rezension zu: Auernhammer - DSGVO/BDSG, Kommentar (7. Auflage, 2020)}, series = {DSB Datenschutz-Berater}, volume = {44}, journal = {DSB Datenschutz-Berater}, number = {10}, publisher = {DFV Mediengruppe}, address = {Frankfurt a.M.}, issn = {0170-7256}, pages = {260}, year = {2020}, language = {de} } @article{HoffstadtPohenDickeetal.2020, author = {Hoffstadt, Kevin and Pohen, Gino D. and Dicke, Max D. and Paulsen, Svea and Krafft, Simone and Zang, Joachim W. and Fonseca-Zang, Warde A. da and Leite, Athaydes and Kuperjans, Isabel}, title = {Challenges and prospects of biogas from energy cane as supplement to bioethanol production}, series = {Agronomy}, volume = {10}, journal = {Agronomy}, number = {6}, publisher = {MDPI}, address = {Basel}, issn = {2073-4395}, doi = {10.3390/agronomy10060821}, year = {2020}, abstract = {Innovative breeds of sugar cane yield up to 2.5 times as much organic matter as conventional breeds, resulting in a great potential for biogas production. The use of biogas production as a complementary solution to conventional and second-generation ethanol production in Brazil may increase the energy produced per hectare in the sugarcane sector. Herein, it was demonstrated that through ensiling, energy cane can be conserved for six months; the stored cane can then be fed into a continuous biogas process. This approach is necessary to achieve year-round biogas production at an industrial scale. Batch tests revealed specific biogas potentials between 400 and 600 LN/kgVS for both the ensiled and non-ensiled energy cane, and the specific biogas potential of a continuous biogas process fed with ensiled energy cane was in the same range. Peak biogas losses through ensiling of up to 27\% after six months were observed. Finally, compared with second-generation ethanol production using energy cane, the results indicated that biogas production from energy cane may lead to higher energy yields per hectare, with an average energy yield of up to 162 MWh/ha. Finally, the Farm²CBG concept is introduced, showing an approach for decentralized biogas production.}, language = {en} } @article{PoghossianJablonskiMolinnusetal.2020, author = {Poghossian, Arshak and Jablonski, Melanie and Molinnus, Denise and Wege, Christina and Sch{\"o}ning, Michael Josef}, title = {Field-Effect Sensors for Virus Detection: From Ebola to SARS-CoV-2 and Plant Viral Enhancers}, series = {Frontiers in Plant Science}, volume = {11}, journal = {Frontiers in Plant Science}, number = {Article 598103}, publisher = {Frontiers}, address = {Lausanne}, doi = {10.3389/fpls.2020.598103}, pages = {1 -- 14}, year = {2020}, abstract = {Coronavirus disease 2019 (COVID-19) is a novel human infectious disease provoked by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Currently, no specific vaccines or drugs against COVID-19 are available. Therefore, early diagnosis and treatment are essential in order to slow the virus spread and to contain the disease outbreak. Hence, new diagnostic tests and devices for virus detection in clinical samples that are faster, more accurate and reliable, easier and cost-efficient than existing ones are needed. Due to the small sizes, fast response time, label-free operation without the need for expensive and time-consuming labeling steps, the possibility of real-time and multiplexed measurements, robustness and portability (point-of-care and on-site testing), biosensors based on semiconductor field-effect devices (FEDs) are one of the most attractive platforms for an electrical detection of charged biomolecules and bioparticles by their intrinsic charge. In this review, recent advances and key developments in the field of label-free detection of viruses (including plant viruses) with various types of FEDs are presented. In recent years, however, certain plant viruses have also attracted additional interest for biosensor layouts: Their repetitive protein subunits arranged at nanometric spacing can be employed for coupling functional molecules. If used as adapters on sensor chip surfaces, they allow an efficient immobilization of analyte-specific recognition and detector elements such as antibodies and enzymes at highest surface densities. The display on plant viral bionanoparticles may also lead to long-time stabilization of sensor molecules upon repeated uses and has the potential to increase sensor performance substantially, compared to conventional layouts. This has been demonstrated in different proof-of-concept biosensor devices. Therefore, richly available plant viral particles, non-pathogenic for animals or humans, might gain novel importance if applied in receptor layers of FEDs. These perspectives are explained and discussed with regard to future detection strategies for COVID-19 and related viral diseases.}, language = {en} } @phdthesis{SteuerDankert2020, author = {Steuer-Dankert, Linda}, title = {Diversity in complex organizations : the triangle of diversity management, change management and organizational culture from a system-theoretical perspective}, doi = {10.18154/RWTH-2020-11830}, pages = {298}, year = {2020}, abstract = {Insbesondere im wirtschaftlichen Kontext wird die Diversit{\"a}t von Belegschaften zunehmend als ein kritischer Erfolgsfaktor gesehen. Neben dem Potenzial, welches sich laut Studien aus einem vielf{\"a}ltigen Team ergibt, werden jedoch ebenfalls die aus menschlicher Diversit{\"a}t resultierenden Herausforderungen thematisiert und wissenschaftlich untersucht. Sowohl aus dem Potenzial als auch aus den Herausforderungen ergibt sich dabei die Notwendigkeit der Implementierung eines organisationsspezifischen Diversity Managements, welches die Gewinnung neuer Mitarbeiter*innen einerseits und das Management der vorhandenen Vielfalt andererseits gleichermaßen unterst{\"u}tzt. In der psychologischen, sozial- und wirtschaftswissenschaftlichen Literatur gibt es unterschiedliche Definitionen von Diversit{\"a}t, woraus sich verschiedene Perspektiven auf das Vorgehen bei der Gestaltung und Umsetzung eines Diversity Management Ansatzes ergeben. Insbesondere vor dem Hintergrund der Komplexit{\"a}t des Organisationsumfeldes und der steigenden Anforderungen an die organisationsinterne Agilit{\"a}t besteht die Notwendigkeit, Diversit{\"a}t in Organisationen st{\"a}rker zu reflektieren und systemspezifische Ans{\"a}tze zu entwickeln. Dies erfordert die Ber{\"u}cksichtigung organisationsspezifischer Strukturen und Prozesse sowie die Reflexion des Wandels der Organisationskultur durch die Umsetzung eines Diversity Management Ansatzes, der die gegebene Komplexit{\"a}t aufgreift und bew{\"a}ltigen kann. Dar{\"u}ber hinaus sind die psychologischen Auswirkungen solcher Ver{\"a}nderungen auf die Mitarbeiter*innen zu ber{\"u}cksichtigen, um Reaktanzen zu vermeiden und eine nachhaltige Umsetzung von Diversity Management zu erm{\"o}glichen. In Ermangelung entsprechender Ans{\"a}tze im Rahmen {\"o}ffentlich finanzierter, komplexer Forschungsorganisationen, ist das Ziel dieser Dissertation die Entwicklung und Erprobung eines Forschungsdesigns, welches die Ans{\"a}tze des Diversity- und Change Managements mit der Organisationskultur verkn{\"u}pft, indem es eine systemtheoretische Perspektive einnimmt. Dabei wird das Forschungsdesign auf eine komplexe wissenschaftliche Organisation angewendet. Als Basis dient die in Teil A durchgef{\"u}hrte Betrachtung des aktuellen Forschungsstandes aus einer interdisziplin{\"a}ren Perspektive und die damit einhergehende umfassende Einf{\"u}hrung in das Forschungsfeld. Im Zuge dessen wird detailliert auf die begriffliche Definition von Diversit{\"a}t eingegangen, bevor dann die psychologischen Konzepte im Diversit{\"a}tskontext den {\"U}bergang zu einer differenzierten Auseinandersetzung mit dem Konzept des Diversity Managements bilden. Auf dieser Grundlage werden das Forschungsdesign sowie die daraus resultierenden Forschungsphasen abgeleitet. Teil A stellt somit die theoretische Grundlage f{\"u}r die in Teil B pr{\"a}sentierten Fachaufs{\"a}tze dar. Jeder Fachaufsatz beleuchtet dabei in chronologischer Reihenfolge die unterschiedlichen Forschungsphasen. Fachaufsatz I pr{\"a}sentiert den sechsstufigen Forschungsansatz und beleuchtet die besonderen Rahmenbedingungen des Forschungsobjektes aus einer theoretischen Perspektive. Im Anschluss werden die Ergebnisse der Organisationsanalyse, welche zugleich Phase I und II des Forschungskonzeptes darstellen, vorgestellt. Aufbauend auf diesen Forschungsergebnissen fokussiert Forschungsaufsatz II die Darlegung der Ergebnisse aus Forschungsphase III, der Befragung der F{\"u}hrungsebene. Die Befragung thematisierte dabei die Wahrnehmung von Diversity und Diversity Management auf F{\"u}hrungsebene, die Verkn{\"u}pfung von Diversit{\"a}t mit Innovation sowie die Reflexion des eigenen F{\"u}hrungsstils. Als Ergebnis der Befragung konnten sechs Typen identifiziert werden, die das F{\"u}hrungsverst{\"a}ndnis im Diversit{\"a}tskontext widerspiegeln und somit den Ansatzpunkt f{\"u}r eine top-down gerichtete Diversity Management Strategie darstellen. Darauf aufbauend wird in Forschungsphase IV die Mitarbeiter*innenebene beforscht. Im Zentrum der quantitativen Befragung standen die vorherrschenden Einstellungen zum Themenkomplex Diversity und Diversity Management, die Wahrnehmung von Diversit{\"a}t sowie die Untersuchung des Einflusses der F{\"u}hrungsebene auf die Mitarbeiter*innenebene. Forschungsaufsatz III pr{\"a}sentiert erste Ergebnisse dieser Untersuchung. Die Analyse weist auf eine unterschiedliche Gewichtung der verschiedenen Diversit{\"a}tskategorien hinsichtlich der Verkn{\"u}pfung mit Innovationen und somit der Reflexion des Kontextes zwischen Diversit{\"a}t und Innovationen hin. Vergleichbar mit den identifizierten Typen auf der F{\"u}hrungsebene, deutet die Analyse auf die Existenz unterschiedlicher Reflexionsgrade auf Mitarbeiter*innenebene hin. Auf Basis dessen wird im Rahmen von Forschungsaufsatz IV eine n{\"a}here Untersuchung des Reflexionsgrades auf Mitarbeiter*innenebene pr{\"a}sentiert und der Diversity Management Ansatz mit Elementen des Change Managements kombiniert. Besondere Ber{\"u}cksichtigung findet als Schlussfolgerung einer theoretischen Analyse die Organisationskultur als zentrales Element bei der Entwicklung und Einf{\"u}hrung eines Diversity Management Ansatzes in eine komplexe Forschungsorganisation in Deutschland. Die Analyse zeigt, dass die Wahrnehmung von Diversit{\"a}t heterogen aber zun{\"a}chst losgel{\"o}st vom individuellen Hintergrund ist (im Rahmen dieser Analyse lag der Fokus auf den Diversit{\"a}tskategorien Gender und Herkunft). Hinsichtlich der Wertsch{\"a}tzung von Diversit{\"a}t zeigt sich dabei ebenfalls ein heterogenes Bild. In der Gesamtbetrachtung stimmen lediglich 17\% der Mitarbeiter*innen zu, dass Diversit{\"a}tskategorien wie Gender, Herkunft oder auch Alter einen Mehrwert darstellen k{\"o}nnen. Zugleich bewertet diese Gruppe die dem Thema beigemessene Wichtigkeit im CoE als ausreichend. Zusammengefasst lassen sich folgende Erkenntnisse im Rahmen dieser Dissertation ableiten und dienen somit als Grundlage f{\"u}r die Entwicklung eines Diversity Management Ansatzes: (1) Die Entwicklung eines bedarfsorientierten Diversity Management Ansatzes erfordert einen systemtheoretischen Prozess, der sowohl organisationsinterne als auch externe Einflussfaktoren ber{\"u}cksichtigt. Der im Rahmen des Forschungsprojektes entwickelte sechsstufige Forschungsprozess hat sich dabei als geeignetes Instrument erwiesen. (2)Im Rahmen {\"o}ffentlicher Forschungseinrichtungen lassen sich dabei drei zentrale Faktoren identifizieren: die individuelle Reflexionsebene, die Organisationskultur sowie extern beeinflusste Organisationsstrukturen, Prozesse und Systeme.(3)Vergleichbar mit privatwirtschaftlichen Unternehmen hat auch in wissenschaftlichen Organisationen die F{\"u}hrungsebene einen maßgeblichen Einfluss auf die Wahrnehmung von Diversit{\"a}t und somit einen Einfluss auf die Umsetzung einer Diversity Management Strategie. Daher ist auch im wissenschaftlichen Kontext, bedingt durch die rechtlichen Rahmenbedingungen des Hochschulsystems, ein top-down Ansatz f{\"u}r eine nachhaltige Implementierung erforderlich. (4) Diversity Management steht in einem engen Zusammenhang mit einem organisationalen Wandel, was die Reflexion von Ver{\"a}nderungsprozesse aus einer psychologischen Perspektive erfordert und eine Verkn{\"u}pfung von Diversity und Change Management bedingt. Aufbauend auf den im Rahmen des entwickelten Forschungskonzeptes gewonnenen zentralen Erkenntnissen wird ein Ansatz entwickelt, der die Ableitung theoretischer Implikationen sowie Implikationen f{\"u}r das Management erm{\"o}glicht. Insbesondere vor dem Hintergrund der Reflexion der besonderen Rahmenbedingungen {\"o}ffentlich finanzierter Forschungsorganisationen werden dar{\"u}ber hinaus politische Implikationen abgeleitet, die auf die Ver{\"a}nderung struktureller Dimensionen abzielen.}, language = {en} } @book{Golland2020, author = {Golland, Alexander}, title = {Kirchliches Datenschutzrecht: Datenschutz-Grundverordnung, Datenschutzvorschriften der Kirchen in Deutschland, Durchf{\"u}hrungsverordnungen und Verfahrensgesetze : Tetxsammlung / herausgegeben von Alexander Golland, mit der Stiftung Datenschutz}, edition = {2. Auflage}, publisher = {DFV Mediengruppe}, address = {Frankfurt a.M.}, isbn = {978-3-8005-1710-7}, pages = {XIII, 341 Seiten}, year = {2020}, abstract = {Textsammlung mit allen f{\"u}r den Datenschutz in Kirchen maßgeblichen Regelwerken: DSGVO, KDG, KDR-OG, DSG-EKD sowie begleitende Verordnungen (KDG-DVO, KDR-OG-DVO und ITSVO-EKD) und Verfahrensgesetze (KDSGO und KiGG.EKD). Die vorliegende Textsammlung enth{\"a}lt die f{\"u}r den Datenschutz der beiden großen Kirchen in Deutschland maßgeblichen Vorschriften: Dies sind, neben der Datenschutz-Grundverordnung, die Normen des kirchlichen Rechts, die neu erlassen bzw. ge{\"a}ndert wurden. Weiter sind die verschiedenen Durchf{\"u}hrungsverordnungen f{\"u}r die kirchlichen Datenschutzgesetze und die maßgeblichen Normen des kirchlichen Verfahrensrechts abgedruckt. Erg{\"a}nzt wird das Werk durch Verweise auf maßgebliche Ver{\"o}ffentlichungen der weltlichen und kirchlichen Datenschutzaufsichtsbeh{\"o}rden und weitere Materialien.}, language = {de} } @incollection{Kleefeld2020, author = {Kleefeld, Andreas}, title = {Numerical calculation of interior transmission eigenvalues with mixed boundary conditions}, series = {Computational and Analytic Methods in Science and Engineering}, booktitle = {Computational and Analytic Methods in Science and Engineering}, editor = {Constanda, Christian}, publisher = {Birkh{\"a}user}, address = {Cham}, isbn = {978-3-030-48185-8 (Hardcover)}, doi = {10.1007/978-3-030-48186-5_9}, pages = {173 -- 195}, year = {2020}, abstract = {Interior transmission eigenvalue problems for the Helmholtz equation play an important role in inverse wave scattering. Some distribution properties of those eigenvalues in the complex plane are reviewed. Further, a new scattering model for the interior transmission eigenvalue problem with mixed boundary conditions is described and an efficient algorithm for computing the interior transmission eigenvalues is proposed. Finally, extensive numerical results for a variety of two-dimensional scatterers are presented to show the validity of the proposed scheme.}, language = {en} } @article{FingerBraunBil2020, author = {Finger, Felix and Braun, Carsten and Bil, Cees}, title = {Comparative assessment of parallel-hybrid-electric propulsion systems for four different aircraft}, series = {Journal of Aircraft}, volume = {57}, journal = {Journal of Aircraft}, number = {5}, publisher = {AIAA}, address = {Reston, Va.}, issn = {1533-3868}, doi = {10.2514/1.C035897}, year = {2020}, abstract = {Until electric energy storage systems are ready to allow fully electric aircraft, the combination of combustion engine and electric motor as a hybrid-electric propulsion system seems to be a promising intermediate solution. Consequently, the design space for future aircraft is expanded considerably, as serial hybrid-electric, parallel hybrid-electric, fully electric, and conventional propulsion systems must all be considered. While the best propulsion system depends on a multitude of requirements and considerations, trends can be observed for certain types of aircraft and certain types of missions. This Paper provides insight into some factors that drive a new design toward either conventional or hybrid propulsion systems. General aviation aircraft, regional transport aircraft vertical takeoff and landing air taxis, and unmanned aerial vehicles are chosen as case studies. Typical missions for each class are considered, and the aircraft are analyzed regarding their takeoff mass and primary energy consumption. For these case studies, a high-level approach is chosen, using an initial sizing methodology. Only parallel-hybrid-electric powertrains are taken into account. Aeropropulsive interaction effects are neglected. Results indicate that hybrid-electric propulsion systems should be considered if the propulsion system is sized by short-duration power constraints. However, if the propulsion system is sized by a continuous power requirement, hybrid-electric systems offer hardly any benefit.}, language = {en} } @article{Golland2020, author = {Golland, Alexander}, title = {Die Zukunft internationaler Datentransfers: Quo vadis?}, year = {2020}, abstract = {Nach dem Scheitern des Privacy Shield hofft der Datenschutzberater Alexander Golland, dass die europ{\"a}ischen Beh{\"o}rden bald konkrete Maßnahmen f{\"u}r den Datentransfer in Drittl{\"a}nder vorschlagen. Auch kleine Unternehmen m{\"u}ssten die Herausforderung bew{\"a}ltigen - sonst w{\"a}re das Urteil nur Wasser auf die M{\"u}hlen jener, die ohnehin {\"u}ber den Datenschutz schimpfen.}, language = {de} } @article{Golland2020, author = {Golland, Alexander}, title = {Datenschutzrechtliche Fragen personalisierter Preise — Herausforderungen von Algorithmen im Schnittbereich von Ethik, {\"O}konomie und Datenschutz}, series = {CR Computer und Recht}, volume = {36}, journal = {CR Computer und Recht}, number = {3}, publisher = {Verlag Dr. Otto Schmidt}, address = {K{\"o}ln}, isbn = {2194-4172}, doi = {10.9785/cr-2020-360313}, pages = {186 -- 194}, year = {2020}, language = {de} } @misc{Golland2020, author = {Golland, Alexander}, title = {Rezension zu: Kipker - Rechtshandbuch Cybersecurity (2020)}, series = {DSB Datenschutz-Berater}, volume = {44}, journal = {DSB Datenschutz-Berater}, number = {7-8}, publisher = {DFV Mediengruppe}, address = {Frankfurt a.M.}, issn = {0170-7256}, pages = {192}, year = {2020}, language = {de} } @misc{Golland2020, author = {Golland, Alexander}, title = {Rezension zu: Gabel/Heinrich/Kiefner - Rechtshandbuch Cyber-Security (2019)}, series = {K\&R Kommunikation \& Recht}, journal = {K\&R Kommunikation \& Recht}, number = {6}, issn = {1434-6354}, pages = {VII}, year = {2020}, language = {de} } @phdthesis{Achtsnicht2020, author = {Achtsnicht, Stefan}, title = {Multiplex-Magnetdetektion von superparamagnetischen Beads zur Identifizierung von Trinkwasserkontaminationen}, doi = {10.18154/RWTH-2020-12052}, pages = {144 Seiten}, year = {2020}, abstract = {Die qualitative und quantitative Detektion von Zielsubstanzen innerhalb einer w{\"a}ssrigen Probe ist f{\"u}r viele Fragestellungen von Interesse, etwa bei der Detektion von Kontaminationen in Trinkwasser in Krisensituationen. Hierbei ist es nicht nur wichtig, dass Pathogene m{\"o}glichst sensitiv detektiert werden k{\"o}nnen, sondern auch, dass die Analyse schnell erfolgt, um Betroffenen im Katastrophenfall z{\"u}gig sicheres Trinkwasser zu Verf{\"u}gung stellen zu k{\"o}nnen. Da bei einem solchen Szenario nicht von einer in der N{\"a}he befindlichen funktionierenden Laborinfrastruktur ausgegangen werden kann, ist es wichtig, dass die Messung direkt vor Ort erfolgen kann. Im Rahmen dieser Arbeit wurde untersucht, ob eine derartige Schnellanalytik mithilfe von superparamagnetischen Beads (MBs) und der magnetischen Frequenzmischtechnik m{\"o}glich ist. Dabei werden die MBs mit Hilfe von prim{\"a}ren Antik{\"o}rpern an die Zielsubstanz gebunden und mit sekund{\"a}ren Antik{\"o}rpern an die Poren-Oberfl{\"a}che eines Polyethylen-Filters fixiert (Sandwich-Immunoassay). So kann die Quantifizierung der Zielsubstanz auf eine magnetische Messung der immobilisierten MB-Marker zur{\"u}ckgef{\"u}hrt werden. Die magnetische Frequenzmischtechnik basiert auf der Anregung der Probe mit Magnetfeldern zweier verschiedener Frequenzen. Die durch die nichtlineare Magnetisierungsform der superparamagnetischen MBs entstehenden Mischfrequenzen werden typischerweise mithilfe einer zweistufigen Lock-in-Detektion analysiert (analoge Demodulation), die in einem Magnetreader als Handheldger{\"a}t realisiert wurde. Zus{\"a}tzlich zu dieser Technik wurde das Prinzip der direkten Digitalisierung des gesamten Antwortsignals mit anschließender Fourier-Analyse der erzeugten Mischfrequenzen experimentell umgesetzt, um die Amplituden und Phasen mehrerer Mischfrequenzen simultan zu erfassen. Eine M{\"o}glichkeit zur Sensitivit{\"a}tssteigerung ist die magnetische Aufkonzentration, indem vor der magnetischen Analyse eine Separation der MBs aus einem gr{\"o}ßeren Probenvolumen mittels magnetischem Feldgradienten durchgef{\"u}hrt wird. Zur Charakterisierung verschiedener kommerzieller MBs hinsichtlich ihrer magnetischen Separierbarkeit wurde ein Aufbau zur Messung ihrer magnetophoretischen Beweglichkeiten realisiert und ihre Geschwindigkeiten im Gradientenfeld mikroskopisch gemessen.Da eine Probe oftmals nicht nur auf eine einzige Zielsubstanz, sondern simultan auf mehrere verschiedene Pathogene hin untersucht werden soll, wurden verschiedene Ans{\"a}tze entwickelt und getestet, die einen solchen multiparametrischen magnetischen Immunoassay erm{\"o}glichen. Einerseits wurde eine r{\"a}umliche Separation der Bindungsbereiche f{\"u}r verschiedene Zielsubstanzen realisiert, die sequentiell ausgewertet werden k{\"o}nnen. Andererseits wurde die Unterscheidung von verschiedenen Zielsubstanzen anhand der Charakteristika der an sie gebundenen, verschieden funktionalisierten MB-Typen untersucht. F{\"u}r eine solche Unterscheidung wurde zum einen die Anregefrequenz der magnetischen Frequenzmischtechnik w{\"a}hrend einer Messung variiert. Damit konnte gezeigt werden, dass sich verschiedene MB-Sorten anhand der Phase ihrer Frequenzmischsignale voneinander unterscheiden lassen. Weiterhin wurde gezeigt, dass sich der Signalverlauf einer bin{\"a}ren Mischung zweier verschiedener MB-Typen als gradueller {\"U}bergang der Verl{\"a}ufe der beiden reinen MB-L{\"o}sungen ergibt. Eine weitere Analysemethode f{\"u}r einen multiparametrischen Immunoassay besteht darin, ein zus{\"a}tzliches einstellbares statisches magnetisches Offsetfeld zu verwenden. Hierf{\"u}r wurden mehrere Aufbauten auf Basis von Permanent- und Elektromagneten simuliert, konstruiert und charakterisiert. Mithilfe von Simulationen konnte gezeigt werden, dass eine auf diesem Verfahren beruhende Unterscheidung f{\"u}r MBs mit unterschiedlichen magnetischen Partikelmomenten m{\"o}glich ist. Als direkte Anwendung des hier entwickelten Magnetreaders in Zusammenspiel mit der digitalen Demodulation wurde ein magnetischer Assay gegen die B-Untereinheit des Choleratoxins in Trinkwasser mit einem niedrigen Detektionslimit von 0,2 ng/ml demonstriert.}, language = {de} } @inproceedings{PaulsenHoffstadtKrafftetal.2020, author = {Paulsen, Svea and Hoffstadt, Kevin and Krafft, Simone and Leite, A. and Zang, J. and Fonseca-Zang, W. and Kuperjans, Isabel}, title = {Continuous biogas production from sugarcane as sole substrate}, series = {Energy Reports}, volume = {6}, booktitle = {Energy Reports}, number = {Supplement 1}, publisher = {Elsevier}, doi = {10.1016/j.egyr.2019.08.035}, pages = {153 -- 158}, year = {2020}, abstract = {A German-Brazilian research project investigates sugarcane as an energy plant in anaerobic digestion for biogas production. The aim of the project is a continuous, efficient, and stable biogas process with sugarcane as the substrate. Tests are carried out in a fermenter with a volume of 10 l. In order to optimize the space-time load to achieve a stable process, a continuous process in laboratory scale has been devised. The daily feed in quantity and the harvest time of the substrate sugarcane has been varied. Analyses of the digester content were conducted twice per week to monitor the process: The ratio of inorganic carbon content to volatile organic acid content (VFA/TAC), the concentration of short-chain fatty acids, the organic dry matter, the pH value, and the total nitrogen, phosphate, and ammonium concentrations were monitored. In addition, the gas quality (the percentages of CO₂, CH₄, and H₂) and the quantity of the produced gas were analyzed. The investigations have exhibited feasible and economical production of biogas in a continuous process with energy cane as substrate. With a daily feeding rate of 1.68gᵥₛ/l*d the average specific gas formation rate was 0.5 m3/kgᵥₛ. The long-term study demonstrates a surprisingly fast metabolism of short-chain fatty acids. This indicates a stable and less susceptible process compared to other substrates.}, language = {en} } @article{OezsoyluKizildagSchoeningetal.2020, author = {{\"O}zsoylu, Dua and Kizildag, Sefa and Sch{\"o}ning, Michael Josef and Wagner, Torsten}, title = {Differential chemical imaging of extracellular acidification within microfluidic channels using a plasma-functionalized light-addressable potentiometric sensor (LAPS)}, series = {Physics in Medicine}, volume = {10}, journal = {Physics in Medicine}, number = {100030}, publisher = {Elsevier}, address = {Amsterdam}, issn = {2352-4510}, doi = {10.1016/j.phmed.2020.100030}, pages = {8}, year = {2020}, abstract = {Extracellular acidification is a basic indicator for alterations in two vital metabolic pathways: glycolysis and cellular respiration. Measuring these alterations by monitoring extracellular acidification using cell-based biosensors such as LAPS plays an important role in studying these pathways whose disorders are associated with numerous diseases including cancer. However, the surface of the biosensors must be specially tailored to ensure high cell compatibility so that cells can represent more in vivo-like behavior, which is critical to gain more realistic in vitro results from the analyses, e.g., drug discovery experiments. In this work, O2 plasma patterning on the LAPS surface is studied to enhance surface features of the sensor chip, e.g., wettability and biofunctionality. The surface treated with O2 plasma for 30 s exhibits enhanced cytocompatibility for adherent CHO-K1 cells, which promotes cell spreading and proliferation. The plasma-modified LAPS chip is then integrated into a microfluidic system, which provides two identical channels to facilitate differential measurements of the extracellular acidification of CHO-K1 cells. To the best of our knowledge, it is the first time that extracellular acidification within microfluidic channels is quantitatively visualized as differential (bio-)chemical images.}, language = {en} } @inproceedings{SildatkeKarwanniKraftetal.2020, author = {Sildatke, Michael and Karwanni, Hendrik and Kraft, Bodo and Schmidts, Oliver and Z{\"u}ndorf, Albert}, title = {Automated Software Quality Monitoring in Research Collaboration Projects}, series = {ICSEW'20: Proceedings of the IEEE/ACM 42nd International Conference on Software Engineering Workshops}, booktitle = {ICSEW'20: Proceedings of the IEEE/ACM 42nd International Conference on Software Engineering Workshops}, publisher = {IEEE}, address = {New York, NY}, doi = {10.1145/3387940.3391478}, pages = {603 -- 610}, year = {2020}, abstract = {In collaborative research projects, both researchers and practitioners work together solving business-critical challenges. These projects often deal with ETL processes, in which humans extract information from non-machine-readable documents by hand. AI-based machine learning models can help to solve this problem. Since machine learning approaches are not deterministic, their quality of output may decrease over time. This fact leads to an overall quality loss of the application which embeds machine learning models. Hence, the software qualities in development and production may differ. Machine learning models are black boxes. That makes practitioners skeptical and increases the inhibition threshold for early productive use of research prototypes. Continuous monitoring of software quality in production offers an early response capability on quality loss and encourages the use of machine learning approaches. Furthermore, experts have to ensure that they integrate possible new inputs into the model training as quickly as possible. In this paper, we introduce an architecture pattern with a reference implementation that extends the concept of Metrics Driven Research Collaboration with an automated software quality monitoring in productive use and a possibility to auto-generate new test data coming from processed documents in production. Through automated monitoring of the software quality and auto-generated test data, this approach ensures that the software quality meets and keeps requested thresholds in productive use, even during further continuous deployment and changing input data.}, language = {en} }