@incollection{BarnatBosseTight2017, author = {Barnat, Miriam and Bosse, Elke and Tight, Malcolm}, title = {The Guiding Role of Theory in Mixed-Methods Research: Combining Individual and Institutional Perspectives on the Transition to Higher Education}, series = {Theory and Method in Higher Education Research. Vol 3}, booktitle = {Theory and Method in Higher Education Research. Vol 3}, publisher = {Emerald Publishing Limited}, isbn = {978-1-78743-222-2}, doi = {10.1108/S2056-375220170000003001}, pages = {1 -- 19}, year = {2017}, abstract = {The methodological discourse of mixed-methods research offers general procedures to combine quantitative and qualitative methods for investigating complex fields of research such as higher education. However, integrating different methods still poses considerable challenges. To move beyond general recommendations for mixed-methods research, this chapter proposes to discuss methodological issues with respect to a particular research domain. Taking current studies on the transition to higher education as an example, the authors first provide an overview of the potentials and limitations of quantitative and qualitative methods in the research domain. Second, they show the need for a conceptual framework grounded in the theory of the research object to guide the integration of different methods and findings. Finally, an example study that investigates transition with regard to the interplay of the individual student and the institutional context serves to illustrate the guiding role of theory. The framework integrates different theoretical perspectives on transition, informs the selection of the research methods, and defines the nexus of the two strands that constitute the mixed-methods design. As the interplay of individual and context is of concern for teaching and learning in general, the example presented may be fruitful for the wider field of higher education research.}, language = {en} } @inproceedings{BaronasIvanauskasKulys2006, author = {Baronas, Romas and Ivanauskas, Feliksas and Kulys, Juozas}, title = {Mathematical modeling of biosensors based on an array of enzyme microreactors}, url = {http://nbn-resolving.de/urn:nbn:de:hbz:a96-opus-1569}, year = {2006}, abstract = {This paper presents a two-dimensional-in-space mathematical model of biosensors based on an array of enzyme microreactors immobilised on a single electrode. The modeling system acts under amperometric conditions. The microreactors were modeled by particles and by strips. The model is based on the diffusion equations containing a nonlinear term related to the Michaelis-Menten kinetics of the enzymatic reaction. The model involves three regions: an array of enzyme microreactors where enzyme reaction as well as mass transport by diffusion takes place, a diffusion limiting region where only the diffusion takes place, and a convective region, where the analyte concentration is maintained constant. Using computer simulation, the influence of the geometry of the microreactors and of the diffusion region on the biosensor response was investigated. The digital simulation was carried out using the finite difference technique.}, subject = {Biosensor}, language = {en} } @article{BaroudWuBohneretal.2003, author = {Baroud, G. and Wu, J.Z. and Bohner, M and Sponagel, Stefan and Steffen, T.}, title = {How to determine the permeability for cement infiltration into osteoporotic cancellous bone}, series = {Medical Engineering \& Physics. 25 (2003), H. 4}, journal = {Medical Engineering \& Physics. 25 (2003), H. 4}, issn = {1350-4533}, pages = {283 -- 288}, year = {2003}, abstract = {Cement augmentation is an emerging surgical procedure in which bone cement is used to infiltrate and reinforce osteoporotic vertebrae. Although this infiltration procedure has been widely applied, it is performed empirically and little is known about the flow characteristics of cement during the injection process. We present a theoretical and experimental approach to investigate the intertrabecular bone permeability during the infiltration procedure. The cement permeability was considered to be dependent on time, bone porosity, and cement viscosity in our analysis. In order to determine the time-dependent permeability, ten cancellous bone cores were harvested from osteoporotic vertebrae, infiltrated with acrylic cement at a constant flow rate, and the pressure drop across the cores during the infiltration was measured. The viscosity dependence of the permeability was determined based on published experimental data. The theoretical model for the permeability as a function of bone porosity and time was then fit to the testing data. Our findings suggest that the intertrabecular bone permeability depends strongly on time. For instance, the initial permeability (60.89 mm4/N.s) reduced to approximately 63\% of its original value within 18 seconds. This study is the first to analyze cement flow through osteoporotic bone. The theoretical and experimental models provided in this paper are generic. Thus, they can be used to systematically study and optimize the infiltration process for clinical practice.}, subject = {Osteoporose}, language = {en} } @article{BarsovBechstedtHardt2001, author = {Barsov, S. and Bechstedt, U. and Hardt, Arno}, title = {ANKE, a new facility for medium energy hadron physics at COSY-J{\"u}lich / S. Barsov [u.a.]}, series = {Nuclear instruments and methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment. Vol. 462, iss. 3}, journal = {Nuclear instruments and methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment. Vol. 462, iss. 3}, issn = {0167-5087 (Print) ; 0168-9002 (E-journal)}, pages = {364 -- 381}, year = {2001}, language = {en} } @article{BartellaKamalScholletal.2019, author = {Bartella, Alexander K. and Kamal, Mohammad and Scholl, Ingrid and Schiffer, Stefan and Steegmann, Julius and Ketelsen, Dominik and H{\"o}lzle, Frank W. and Lethaus, Bernd}, title = {Virtual reality in preoperative imaging in maxillofacial surgery: implementation of "the next level"?}, series = {British Journal of Oral and Maxillofacial Surgery}, volume = {57}, journal = {British Journal of Oral and Maxillofacial Surgery}, number = {7}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0266-4356}, doi = {10.1016/j.bjoms.2019.02.014}, pages = {644 -- 648}, year = {2019}, language = {en} } @article{BassamArtmannHescheleretal.2011, author = {Bassam, Rasha and Artmann, Gerhard and Hescheler, J{\"u}rgen and Graef, T. and Temiz Artmann, Ayseg{\"u}l and Porst, Dariusz and Linder, Peter and Kayser, Peter and Arinkin, Vladimir and Gossmann, Matthias and Digel, Ilya}, title = {Alterations in human hemoglobin structure related to red blood cell storage}, year = {2011}, abstract = {The importance of the availability of stored blood or blood cells, respectively, for urgent transfusion cannot be overestimated. Nowadays, blood storage becomes even more important since blood products are used for epidemiological studies, bio-technical research or banked for transfusion purposes. Thus blood samples must not only be processed, stored, and shipped to preserve their efficacy and safety, but also all parameters of storage must be recorded and reported for Quality Assurance. Therefore, blood banks and clinical research facilities are seeking more accurate, automated means for blood storage and blood processing.}, subject = {H{\"a}moglobin}, language = {en} } @inproceedings{BassamDigelArtmann2009, author = {Bassam, Rasha and Digel, Ilya and Artmann, Gerhard}, title = {Effect of nitric oxide on protein thermal stability : [abstract]}, year = {2009}, abstract = {As a deduction from these results, we can conclude that proteins mainly in vitro, denaturate totally at a temperature between 57°C -62°C, and they also affected by NO and different ions types. In which mainly, NO cause earlier protein denaturation, which means that, NO has a destabilizing effect on proteins, and also different ions will alter the protein denaturation in which, some ions will cause earlier protein denaturation while others not.}, subject = {Stickstoffmonoxid}, language = {en} } @article{BassamDigelHescheleretal.2013, author = {Bassam, Rasha and Digel, Ilya and Hescheler, J{\"u}rgen and Temiz Artmann, Ayseg{\"u}l and Artmann, Gerhard}, title = {Effects of spermine NONOate and ATP on protein aggregation: light scattering evidences}, series = {BMC Biophysics}, journal = {BMC Biophysics}, publisher = {BioMed Central}, address = {London}, isbn = {2046-1682}, url = {http://nbn-resolving.de/10.1186/2046-1682-6-1}, pages = {1 -- 14}, year = {2013}, language = {en} } @article{BassamHeschelerTemizArtmannetal.2012, author = {Bassam, Rasha and Hescheler, J{\"u}rgen and Temiz Artmann, Ayseg{\"u}l and Artmann, Gerhard and Digel, Ilya}, title = {Effects of spermine NONOate and ATP on the thermal stability of hemoglobin}, series = {BMC Biophysics}, volume = {5}, journal = {BMC Biophysics}, publisher = {BioMed Central}, address = {London}, issn = {2046-1682}, doi = {10.1186/2046-1682-5-16}, pages = {Art. 16}, year = {2012}, abstract = {Background Minor changes in protein structure induced by small organic and inorganic molecules can result in significant metabolic effects. The effects can be even more profound if the molecular players are chemically active and present in the cell in considerable amounts. The aim of our study was to investigate effects of a nitric oxide donor (spermine NONOate), ATP and sodium/potassium environment on the dynamics of thermal unfolding of human hemoglobin (Hb). The effect of these molecules was examined by means of circular dichroism spectrometry (CD) in the temperature range between 25°C and 70°C. The alpha-helical content of buffered hemoglobin samples (0.1 mg/ml) was estimated via ellipticity change measurements at a heating rate of 1°C/min. Results Major results were: 1) spermine NONOate persistently decreased the hemoglobin unfolding temperature T u irrespectively of the Na + /K + environment, 2) ATP instead increased the unfolding temperature by 3°C in both sodium-based and potassium-based buffers and 3) mutual effects of ATP and NO were strongly influenced by particular buffer ionic compositions. Moreover, the presence of potassium facilitated a partial unfolding of alpha-helical structures even at room temperature. Conclusion The obtained data might shed more light on molecular mechanisms and biophysics involved in the regulation of protein activity by small solutes in the cell.}, language = {en} } @inproceedings{Baumann1989, author = {Baumann, Marcus}, title = {Primary production and phytoplankton growth in the marginal ice zone of the Fram Strait and the interpretation of the field data with autecological experiments (Abstract)}, series = {Oceanography and biology of Arctic seas : selected papers from the ICES Symposium on Marine Sciences of the Arctic and Subarctic Regions, held in Santander, 28 - 30 September 1987. (Rapports et proc{\`e}s-verbaux des r{\´e}unions / Conseil International pour l'Exploration de la Mer ; 188)}, booktitle = {Oceanography and biology of Arctic seas : selected papers from the ICES Symposium on Marine Sciences of the Arctic and Subarctic Regions, held in Santander, 28 - 30 September 1987. (Rapports et proc{\`e}s-verbaux des r{\´e}unions / Conseil International pour l'Exploration de la Mer ; 188)}, editor = {Hempel, G.}, publisher = {International Council for the Exploration of the Sea}, address = {Copenhagen}, organization = {Symposium on Marine Sciences of the Arctic and Subarctic Regions <1987, Santander>}, pages = {128}, year = {1989}, language = {en} } @article{BaumannBrandiniStaubes1994, author = {Baumann, Marcus and Brandini, Frederico and Staubes, Regina}, title = {The influence of light and temperature on carbonspecific DMS release by cultures of Phaeocystis antarctica and three antarctic diatoms / Baumann, Marcus E.M. ; Brandini, Frederico ; Staubes, Regina}, series = {Marine Chemistry. 45 (1994), H. 1-2}, journal = {Marine Chemistry. 45 (1994), H. 1-2}, isbn = {0304-4203}, pages = {129 -- 136}, year = {1994}, language = {en} } @article{BaumannGoeyensSemenehetal.1998, author = {Baumann, Marcus and Goeyens, L. and Semeneh, M. and Elskens, M.}, title = {Phytoplankton nutrient utilisation and nutrient signature in the Southern Ocean / Goeyens, L. ; Semeneh, M. ; Baumann, M.E.M. ; Elskens, M. ; Shopova, D. ; Dehairs, F.}, series = {Journal of Marine Systems. 17 (1998), H. 1-4}, journal = {Journal of Marine Systems. 17 (1998), H. 1-4}, isbn = {0924-7963}, pages = {143 -- 157}, year = {1998}, language = {en} } @article{BaumannGradinger1991, author = {Baumann, Marcus and Gradinger, R.}, title = {Distribution of Phytoplankton Communities in Relation to the Large Scale Hydrographical Regime in the Fram Strait 1984 / Gradinger, R. ; Baumann, M.E.M.}, series = {Marine Biology. 111 (1991), H. 2}, journal = {Marine Biology. 111 (1991), H. 2}, isbn = {0025-3162}, pages = {311 -- 321}, year = {1991}, language = {en} } @article{BaumannHircheKattneretal.1991, author = {Baumann, Marcus and Hirche, H.-J. and Kattner, G. and Gradinger, R.}, title = {Plankton distribution and the impact of copepod grazing on primary production in Fram Strait, Greenland Sea / Hirche, H.-J. ; Baumann, M.E.M. ; Kattner, G.; Gradinger, R.}, series = {Journal of Marine Systems. 2 (1991), H. 3-4}, journal = {Journal of Marine Systems. 2 (1991), H. 3-4}, isbn = {0924-7963}, pages = {477 -- 494}, year = {1991}, language = {en} } @article{BaumannJahnke1983, author = {Baumann, Marcus and Jahnke, J.}, title = {Chemical and Physical Effects on the Shape and Growth of the Diatom Biddulphia sinensis GREVILLE in Batch Cultures: A Contribution to Bioindication in Plankton Ecology / Jahnke, J. ; Baumann, M.}, series = {Hydrobiological Bulletin . 17 (1983), H. 1}, journal = {Hydrobiological Bulletin . 17 (1983), H. 1}, isbn = {0165-1404}, pages = {5 -- 20}, year = {1983}, language = {en} } @article{BaumannLancelotBrandinietal.1994, author = {Baumann, Marcus and Lancelot, C. and Brandini, F. and Sakshaug, E.}, title = {The taxonomic identity of the cosmopolitan prymnesiophyte Phaeocystis, a morphological and ecophysiological approach / Baumann, M.E.M. ; Lancelot, C. ; Brandini, F. ; Sakshaug, E. ; John M.}, series = {Journal of Marine Systems. 5 (1994), H. 1}, journal = {Journal of Marine Systems. 5 (1994), H. 1}, isbn = {0924-7963}, pages = {5 -- 22}, year = {1994}, language = {en} } @article{BaumannLaraHubbertenetal.1997, author = {Baumann, Marcus and Lara, R.J. and Hubberten, D.N. and Thomas, D.N.}, title = {Dissolved organic matter studies in enclosed systems: Application of hydophobic fractionation for the assessment of organic nitrogen dynamics / Lara, R.J. ; Hubberten, U. ; Thomas, D.N. ; Baumann, M.E.M. ; Kattner, G.}, series = {Journal of Marine Systems. 13 (1997), H. 1-4}, journal = {Journal of Marine Systems. 13 (1997), H. 1-4}, isbn = {0924-7963}, pages = {155 -- 161}, year = {1997}, language = {en} } @article{BaumannRousseauVaulotetal.1994, author = {Baumann, Marcus and Rousseau, V. and Vaulot, D. and Casotti, R.}, title = {The life cycle of Phaeocystis (Prymnesiophycae): evidence and hypotheses / Rousseau, V. ; Vaulot, D. ; Casotti, R. ; Cariou, V. ; Lenz, J. ; Gunkel, J. ; Baumann, M.}, series = {Journal of Marine Systems. 5 (1994), H. 1}, journal = {Journal of Marine Systems. 5 (1994), H. 1}, isbn = {0924-7963}, pages = {23 -- 39}, year = {1994}, language = {en} } @article{BaumannSchwarzKotliaretal.2009, author = {Baumann, Marcus and Schwarz, Sonja and Kotliar, Konstantin and Eynatten, Maximilian von and Trucksaess, Arno and Burckhardt, Klaus and Lutz, Jens and Heemann, Uwe and Lanzl, Ines}, title = {Non-diabetic chronic kidney disease influences retinal microvasculature}, series = {Kidney and Blood Pressure Research}, volume = {32}, journal = {Kidney and Blood Pressure Research}, number = {6}, publisher = {-}, isbn = {1423-0143}, pages = {428 -- 433}, year = {2009}, language = {en} } @article{BaumannSemenehDehairsetal.1998, author = {Baumann, Marcus and Semeneh, M. and Dehairs, F. and Elskens, M.}, title = {Nitrogen uptake regime and phytoplankton community structure in the Southern Ocean / Semeneh, M. ; Dehairs, F. ; Elskens, M. ; Baumann, M.E.M. ; Kopczynska, E.E. ; Lancelot, C. ; Goeyens, L.}, series = {Journal of Marine Systems. 17 (1998), H. 1-4}, journal = {Journal of Marine Systems. 17 (1998), H. 1-4}, isbn = {0924-7963}, pages = {159 -- 177}, year = {1998}, language = {en} } @article{BaumannThomasGleitz1992, author = {Baumann, Marcus and Thomas, D. and Gleitz, M.}, title = {Efficiency of carbon assimilation and photoacclimation in a small unicellular Chaetoceros species from the Weddel Sea (Antarctica): Influence of temperature and irridiance / Thomas, D. ; Baumann, M.E.M. ; Gleitz, M.}, series = {Journal of Experimental Marine Biology and Ecology. 157 (1992), H. 2}, journal = {Journal of Experimental Marine Biology and Ecology. 157 (1992), H. 2}, isbn = {0022-0981}, pages = {195 -- 209}, year = {1992}, language = {en} } @article{BaumannTillmannAletsee1989, author = {Baumann, Marcus and Tillmann, U. and Aletsee, L.}, title = {Distribution of Carbon Among Photosynthetic End Products in the Bloom-Forming Arctic Diatom Thalassiosira antarctica COMBER / Tillmann, U. ; Baumann, M.E.M. ; Aletsee, L.}, series = {Polar Biology. 10 (1989), H. 3}, journal = {Polar Biology. 10 (1989), H. 3}, isbn = {0722-4060}, pages = {231 -- 238}, year = {1989}, language = {en} } @inproceedings{BaumannTeixeiraBouraGoettscheetal.2010, author = {Baumann, T. and Teixeira Boura, Cristiano Jos{\´e} and G{\"o}ttsche, Joachim and Hoffschmidt, Bernhard and O'Connell, B. and Schmitz, S. and Zunft, S.}, title = {Air/Sand heat exchanger design and materials for solar thermal power plant applications}, series = {SolarPACES 2010 : the CSP Conference: electricity, fuels and clean water from concentrated solar energy ; 21 to 24 September 2010, Perpignan, France}, booktitle = {SolarPACES 2010 : the CSP Conference: electricity, fuels and clean water from concentrated solar energy ; 21 to 24 September 2010, Perpignan, France}, publisher = {Soc. OSC}, address = {Saint Maur}, pages = {146 -- 147}, year = {2010}, language = {en} } @inproceedings{BaumannTeixeiraBouraEcksteinetal.2012, author = {Baumann, Torsten and Teixeira Boura, Cristiano Jos{\´e} and Eckstein, Julian and Dabrowski, Jan and G{\"o}ttsche, Joachim and Hoffschmidt, Bernhard and Schmitz, Stefan and Zunft, Stefan}, title = {Properties of bulk materials for high-temperature air-sand heat exchangers}, series = {30th ISES Biennial Solar World Congress 2011 : Kassel, Germany, 28 August - 2 September 2011. Vol. 2}, booktitle = {30th ISES Biennial Solar World Congress 2011 : Kassel, Germany, 28 August - 2 September 2011. Vol. 2}, publisher = {Curran}, address = {Red Hook, NY}, organization = {International Solar Energy Society}, isbn = {978-1-61839-364-7}, pages = {1270 -- 1278}, year = {2012}, language = {en} } @inproceedings{BaumannTeixeiraBouraGoettscheetal.2011, author = {Baumann, Torsten and Teixeira Boura, Cristiano Jos{\´e} and G{\"o}ttsche, Joachim and Hoffschmidt, Bernhard and Schmitz, Stefan and Zunft, Stefan}, title = {Air-sand heat exchanger: materials and flow properties}, series = {SolarPACES 2011 : concentrating solar power and chemical energy systems : 20 - 23 September, 2011, Granada, Spain}, booktitle = {SolarPACES 2011 : concentrating solar power and chemical energy systems : 20 - 23 September, 2011, Granada, Spain}, address = {Granada}, pages = {1 CD-ROM}, year = {2011}, language = {en} } @misc{BaumgartnerWunderlichJaunichetal.2012, author = {Baumgartner, Thomas and Wunderlich, Florian and Jaunich, Arthur and Sato, Tomoo and Bundy, Georg and Grießmann, Nadine and Kowalski, Julia and Burghardt, Stefan and Hanebrink, J{\"o}rg}, title = {Lighting the way: Perspectives on the global lighting market}, edition = {2nd ed.}, address = {McKinsey}, pages = {58}, year = {2012}, language = {en} } @article{BaumgartnerFidlerWethetal.2008, author = {Baumgartner, Werner and Fidler, Florian and Weth, Agnes and Habbecke, Martin and Jakob, Peter and Butenweg, Christoph and B{\"o}hme, Wolfgang}, title = {Investigating the locomotion of the sandfish in desert sand using NMR-Imaging}, series = {PLOS ONE}, volume = {3}, journal = {PLOS ONE}, number = {10}, publisher = {Plos}, address = {San Francisco, California, US}, issn = {1932-6203}, doi = {10.1371/journal.pone.0003309}, pages = {e3309}, year = {2008}, abstract = {The sandfish (Scincus scincus) is a lizard having the remarkable ability to move through desert sand for significant distances. It is well adapted to living in loose sand by virtue of a combination of morphological and behavioural specializations. We investigated the bodyform of the sandfish using 3D-laserscanning and explored its locomotion in loose desert sand using fast nuclear magnetic resonance (NMR) imaging. The sandfish exhibits an in-plane meandering motion with a frequency of about 3 Hz and an amplitude of about half its body length accompanied by swimming-like (or trotting) movements of its limbs. No torsion of the body was observed, a movement required for a digging-behaviour. Simple calculations based on the Janssen model for granular material related to our findings on bodyform and locomotor behaviour render a local decompaction of the sand surrounding the moving sandfish very likely. Thus the sand locally behaves as a viscous fluid and not as a solid material. In this fluidised sand the sandfish is able to "swim" using its limbs.}, language = {en} } @phdthesis{Bayer2021, author = {Bayer, Robin}, title = {Development of a novel in-vitro vascular model for determination of physiological and pathophysiological mechanobiology}, publisher = {Universit{\"a}t zu K{\"o}ln}, address = {K{\"o}ln}, url = {http://nbn-resolving.de/urn:nbn:de:hbz:38-362212}, pages = {IV, 115 Seiten}, year = {2021}, language = {en} } @inproceedings{BayerHeschelerArtmannetal.2019, author = {Bayer, Robin and Hescheler, J{\"u}rgen and Artmann, Gerhard and Temiz Artmann, Ayseg{\"u}l}, title = {Treating arterial hypertension in a cell culture well}, series = {3rd YRA MedTech Symposium 2019 : May 24 / 2019 / FH AachenW}, booktitle = {3rd YRA MedTech Symposium 2019 : May 24 / 2019 / FH AachenW}, editor = {Staat, Manfred and Erni, Daniel}, publisher = {Universit{\"a}t Duisburg-Essen}, address = {Duisburg}, organization = {MedTech Symposium}, isbn = {978-3-940402-22-6}, doi = {10.17185/duepublico/48750}, pages = {5 -- 6}, year = {2019}, abstract = {Hypertension describes the pathological increase of blood pressure, which is most commonly associated with the increase of vascular wall stiffness [1]. Referring to the "Deutsche Bluthochdruck Liga" this pathology shows a growing trend in our aging society. In order to find novel pharmacological and probably personalized treatments, we want to present a functional approach to study biomechanical properties of a human aortic vascular model. In this method review we will give an overview of recent studies which were carried out with the CellDrum technology [2] and underline the added value to already existing standard procedures known from the field of physiology. Herein described CellDrum technology is a system to measure functional mechanical properties of cell monolayers and thin tissue constructs in-vitro. Additionally, the CellDrum enables to elucidate the mechanical response of cells to pharmacological drugs, toxins and vasoactive agents. Due to its highly flexible polymer support, cells can also be mechanically stimulated by steady and cyclic biaxial stretching.}, language = {en} } @article{BayerTemizArtmannDigeletal.2020, author = {Bayer, Robin and Temiz Artmann, Ayseg{\"u}l and Digel, Ilya and Falkenstein, Julia and Artmann, Gerhard and Creutz, Till and Hescheler, J{\"u}rgen}, title = {Mechano-pharmacological testing of L-Type Ca²⁺ channel modulators via human vascular celldrum model}, series = {Cellular Physiology and Biochemistry}, volume = {54}, journal = {Cellular Physiology and Biochemistry}, publisher = {Cell Physiol Biochem Press}, address = {D{\"u}sseldorf}, issn = {1421-9778}, doi = {10.33594/000000225}, pages = {371 -- 383}, year = {2020}, abstract = {Background/Aims: This study aimed to establish a precise and well-defined working model, assessing pharmaceutical effects on vascular smooth muscle cell monolayer in-vitro. It describes various analysis techniques to determine the most suitable to measure the biomechanical impact of vasoactive agents by using CellDrum technology. Methods: The so-called CellDrum technology was applied to analyse the biomechanical properties of confluent human aorta muscle cells (haSMC) in monolayer. The cell generated tensions deviations in the range of a few N/m² are evaluated by the CellDrum technology. This study focuses on the dilative and contractive effects of L-type Ca²⁺ channel agonists and antagonists, respectively. We analyzed the effects of Bay K8644, nifedipine and verapamil. Three different measurement modes were developed and applied to determine the most appropriate analysis technique for the study purpose. These three operation modes are called, particular time mode" (PTM), "long term mode" (LTM) and "real-time mode" (RTM). Results: It was possible to quantify the biomechanical response of haSMCs to the addition of vasoactive agents using CellDrum technology. Due to the supplementation of 100nM Bay K8644, the tension increased approximately 10.6\% from initial tension maximum, whereas, the treatment with nifedipine and verapamil caused a significant decrease in cellular tension: 10nM nifedipine decreased the biomechanical stress around 6,5\% and 50nM verapamil by 2,8\%, compared to the initial tension maximum. Additionally, all tested measurement modes provide similar results while focusing on different analysis parameters. Conclusion: The CellDrum technology allows highly sensitive biomechanical stress measurements of cultured haSMC monolayers. The mechanical stress responses evoked by the application of vasoactive calcium channel modulators were quantified functionally (N/m²). All tested operation modes resulted in equal findings, whereas each mode features operation-related data analysis.}, language = {en} } @article{BayonValeroGarciaBartualetal.2016, author = {Bayon, Arnau and Valero, Daniel and Garcia-Bartual, Rafael and Vall{\´e}s-Mor{\´a}n, Francisco Jos{\´e} and L{\´o}pez-Jim{\´e}nez, P. Amparo}, title = {Performance assessment of OpenFOAM and FLOW-3D in the numerical modeling of a low Reynolds number hydraulic jump}, series = {Environmental Modelling \& Software}, volume = {80}, journal = {Environmental Modelling \& Software}, publisher = {Elsevier}, address = {Amsterdam}, isbn = {1364-8152}, doi = {10.1016/j.envsoft.2016.02.018}, pages = {322 -- 335}, year = {2016}, abstract = {A comparative performance analysis of the CFD platforms OpenFOAM and FLOW-3D is presented, focusing on a 3D swirling turbulent flow: a steady hydraulic jump at low Reynolds number. Turbulence is treated using RANS approach RNG k-ε. A Volume Of Fluid (VOF) method is used to track the air-water interface, consequently aeration is modeled using an Eulerian-Eulerian approach. Structured meshes of cubic elements are used to discretize the channel geometry. The numerical model accuracy is assessed comparing representative hydraulic jump variables (sequent depth ratio, roller length, mean velocity profiles, velocity decay or free surface profile) to experimental data. The model results are also compared to previous studies to broaden the result validation. Both codes reproduced the phenomenon under study concurring with experimental data, although special care must be taken when swirling flows occur. Both models can be used to reproduce the hydraulic performance of energy dissipation structures at low Reynolds numbers.}, language = {en} } @book{BaueerGilchRathetal.1990, author = {Ba{\"u}er, Herbert and Gilch, Heinz Gerhard and Rath, Walter and Sch{\"u}mann, Uwe}, title = {Moisture-curing polyurethane-based hot-melt compositions = Feuchth{\"a}rtbare Heisschmelz-Zusammensetzungen auf Polyurethanbasis}, publisher = {Europ{\"a}isches Patentamt}, address = {M{\"u}nchen}, year = {1990}, language = {en} } @incollection{BechstedtBergHackeretal.1995, author = {Bechstedt, U. and Berg, Georg P. A. and Hacker, U. and Hardt, Arno and H{\"u}rlimann, W. and Maier, R. and Martin, S. and Meissburger, J. and R{\"o}mer, J. G. M. and Possen, P. von and Sagefka, T.}, title = {BIG KARL and COSY}, series = {The art and science of magnet design. A Festschrift in honor of Klaus Halbach. Vol. 1}, booktitle = {The art and science of magnet design. A Festschrift in honor of Klaus Halbach. Vol. 1}, publisher = {Lawrence Berkeley Lab., Univ. of California}, address = {Berkeley, CA.}, pages = {19 -- 28}, year = {1995}, language = {en} } @article{BechstedtHaasHackeretal.1985, author = {Bechstedt, U. and Haas, H. and Hacker, U. and Hardt, Arno and Henn, K. and Martin, S. and Wimmer, J.}, title = {Magnets for the German Spallation Source SNQ}, series = {IEEE transactions on nuclear science. Vol. 32, iss. 5}, journal = {IEEE transactions on nuclear science. Vol. 32, iss. 5}, issn = {1558-1578 (E-Journal); 0018-9499 (Print)}, pages = {3631 -- 3633}, year = {1985}, language = {en} } @article{BechtSchollmayerMonakhovaetal.2021, author = {Becht, Alexander and Schollmayer, Curd and Monakhova, Yulia and Holzgrabe, Ulrike}, title = {Tracing the origin of paracetamol tablets by near-infrared, mid-infrared, and nuclear magnetic resonance spectroscopy using principal component analysis and linear discriminant analysis}, series = {Analytical and Bioanalytical Chemistry}, volume = {413}, journal = {Analytical and Bioanalytical Chemistry}, publisher = {Springer Nature}, issn = {1618-2650}, doi = {10.1007/s00216-021-03249-z}, pages = {3107 -- 3118}, year = {2021}, abstract = {Most drugs are no longer produced in their own countries by the pharmaceutical companies, but by contract manufacturers or at manufacturing sites in countries that can produce more cheaply. This not only makes it difficult to trace them back but also leaves room for criminal organizations to fake them unnoticed. For these reasons, it is becoming increasingly difficult to determine the exact origin of drugs. The goal of this work was to investigate how exactly this is possible by using different spectroscopic methods like nuclear magnetic resonance and near- and mid-infrared spectroscopy in combination with multivariate data analysis. As an example, 56 out of 64 different paracetamol preparations, collected from 19 countries around the world, were chosen to investigate whether it is possible to determine the pharmaceutical company, manufacturing site, or country of origin. By means of suitable pre-processing of the spectra and the different information contained in each method, principal component analysis was able to evaluate manufacturing relationships between individual companies and to differentiate between production sites or formulations. Linear discriminant analysis showed different results depending on the spectral method and purpose. For all spectroscopic methods, it was found that the classification of the preparations to their manufacturer achieves better results than the classification to their pharmaceutical company. The best results were obtained with nuclear magnetic resonance and near-infrared data, with 94.6\%/99.6\% and 98.7/100\% of the spectra of the preparations correctly assigned to their pharmaceutical company or manufacturer.}, language = {en} } @article{BeckBuchleitnerFerreinetal.2014, author = {Beck, Daniel and Buchleitner, Martin and Ferrein, Alexander and Niem{\"u}ller, Tim and Steinbauer, Gerald}, title = {Mostly Harmless \& AllemaniACs - mixed innovations}, pages = {1 -- 8}, year = {2014}, language = {en} } @article{BeckenbachScheidweiler2016, author = {Beckenbach, Isabel and Scheidweiler, Robert}, title = {Perfect ƒ-Matchings and ƒ-Factors in Hypergraphs - A Combinatorial Approach}, series = {Discrete Mathematics}, volume = {240}, journal = {Discrete Mathematics}, number = {10}, publisher = {Elsevier}, address = {Amsterdam}, issn = {2192-7782}, doi = {10.1016/j.disc.2017.05.005}, pages = {2499 -- 2506}, year = {2016}, abstract = {We prove characterizations of the existence of perfect ƒ-matchings in uniform mengerian and perfect hypergraphs. Moreover, we investigate the ƒ-factor problem in balanced hypergraphs. For uniform balanced hypergraphs we prove two existence theorems with purely combinatorial arguments, whereas for non-uniform balanced hypergraphs we show that the ƒ-factor problem is NP-hard.}, language = {en} } @article{BeckerWallangArtmannetal.2008, author = {Becker, C. and Wallang, C. and Artmann, Gerhard and Jakse, G.}, title = {Mechanotransduction-bioreactor for tissue engineering of a ureter prosthesis}, series = {International Journal of Artificial Organs, The}, volume = {31}, journal = {International Journal of Artificial Organs, The}, number = {7}, issn = {0391-3988}, pages = {583 -- 583}, year = {2008}, language = {en} } @inproceedings{BeckerBergenerBreukeretal.2011, author = {Becker, J{\"o}rg and Bergener, Philipp and Breuker, Dominic and Delfmann, Patrick and Eggert, Mathias}, title = {An Efficient Business Process Compliance Checking Approach}, series = {Governance and Sustainability in Information Systems. Managing the Transfer and Diffusion of IT : IFIP WG 8.6 International Working Conference, Hamburg, Germany, September 22-24, 2011. Proceedings}, booktitle = {Governance and Sustainability in Information Systems. Managing the Transfer and Diffusion of IT : IFIP WG 8.6 International Working Conference, Hamburg, Germany, September 22-24, 2011. Proceedings}, publisher = {Springer}, address = {Berlin, Heidelberg}, doi = {10.1007/978-3-642-24148-2_19}, pages = {282 -- 287}, year = {2011}, language = {en} } @inproceedings{BeckerBergenerDelfmannetal.2011, author = {Becker, J{\"o}rg and Bergener, Philipp and Delfmann, Patrick and Eggert, Mathias and Weiss, Burkhard}, title = {Supporting Business Process Compliance in Financial Institutions - A Model-Driven Approach}, series = {Proceedings of the 10th International Conference on Wirtschaftsinformatik : 16 - 18 February 2011, Zurich, Switzerland}, booktitle = {Proceedings of the 10th International Conference on Wirtschaftsinformatik : 16 - 18 February 2011, Zurich, Switzerland}, pages = {355 -- 364}, year = {2011}, language = {en} } @article{BeckerDelfmannDietrichetal.2016, author = {Becker, J{\"o}rg and Delfmann, Patrick and Dietrich, Hanns-Alexander and Steinhorst, Matthias and Eggert, Mathias}, title = {Business Process Compliance Checking — Applying and Evaluating a Generic Pattern Matching Approach for Conceptual Models in the Financial Sector}, series = {Information Systems Frontiers}, volume = {18}, journal = {Information Systems Frontiers}, number = {2}, publisher = {Springer}, address = {Berlin}, issn = {1572-9419}, doi = {10.1007/s10796-014-9529-y}, pages = {359 -- 405}, year = {2016}, abstract = {Given the strong increase in regulatory requirements for business processes the management of business process compliance becomes a more and more regarded field in IS research. Several methods have been developed to support compliance checking of conceptual models. However, their focus on distinct modeling languages and mostly linear (i.e., predecessor-successor related) compliance rules may hinder widespread adoption and application in practice. Furthermore, hardly any of them has been evaluated in a real-world setting. We address this issue by applying a generic pattern matching approach for conceptual models to business process compliance checking in the financial sector. It consists of a model query language, a search algorithm and a corresponding modelling tool prototype. It is (1) applicable for all graph-based conceptual modeling languages and (2) for different kinds of compliance rules. Furthermore, based on an applicability check, we (3) evaluate the approach in a financial industry project setting against its relevance for decision support of audit and compliance management tasks.}, language = {en} } @article{BeckerDelfmannEggertetal.2012, author = {Becker, J{\"o}rg and Delfmann, Patrick and Eggert, Mathias and Schwittay, Sebastian}, title = {Generalizability and Applicability of Model-Based Business Process Compliance-Checking Approaches — A State-of-the-Art Analysis and Research Roadmap}, series = {Business Research : BuR}, volume = {5}, journal = {Business Research : BuR}, number = {2}, publisher = {Springer}, address = {Heidelberg}, issn = {1866-8658}, doi = {10.1007/BF03342739}, pages = {221 -- 247}, year = {2012}, abstract = {With a steady increase of regulatory requirements for business processes, automation support of compliance management is a field garnering increasing attention in Information Systems research. Several approaches have been developed to support compliance checking of process models. One major challenge for such approaches is their ability to handle different modeling techniques and compliance rules in order to enable widespread adoption and application. Applying a structured literature search strategy, we reflect and discuss compliance-checking approaches in order to provide an insight into their generalizability and evaluation. The results imply that current approaches mainly focus on special modeling techniques and/or a restricted set of types of compliance rules. Most approaches abstain from real-world evaluation which raises the question of their practical applicability. Referring to the search results, we propose a roadmap for further research in model-based business process compliance checking.}, language = {en} } @inproceedings{BeckerEggertBruningetal.2013, author = {Becker, J{\"o}rg and Eggert, Mathias and Bruning, Dennis and Saat, Jan}, title = {Applicability of Business Process Model Analysis Approaches - A Case Study in Financial Services Consulting}, series = {Wirtschaftsinformatik Proceedings 2013}, booktitle = {Wirtschaftsinformatik Proceedings 2013}, pages = {1181 -- 1195}, year = {2013}, language = {en} } @inproceedings{BeckerEggertFleischeretal.2013, author = {Becker, J{\"o}rg and Eggert, Mathias and Fleischer, Stefan and Knackstedt, Ralf}, title = {How to Teach Regulatory Compliant Data Warehouse Engineering?}, series = {Proceedings of the Nineteenth Americas Conference on Information Systems, Chicago, Illinois, August 15-17, 2013.}, booktitle = {Proceedings of the Nineteenth Americas Conference on Information Systems, Chicago, Illinois, August 15-17, 2013.}, pages = {10 S.}, year = {2013}, language = {en} } @inproceedings{BeckerEggertHeddieretal.2012, author = {Becker, J{\"o}rg and Eggert, Mathias and Heddier, Marcel and Knackstedt, Ralf}, title = {Merging Conceptual Modeling and Law for Legally Compliant Information Systems Design - A Framework-Based Research Agenda}, series = {45th Hawaii International Conference on System Sciences 2012}, booktitle = {45th Hawaii International Conference on System Sciences 2012}, isbn = {978-0-7695-4525-7}, doi = {10.1109/HICSS.2012.428}, pages = {5241 -- 5248}, year = {2012}, language = {en} } @inproceedings{BeckerEggertSaatetal.2013, author = {Becker, J{\"o}rg and Eggert, Mathias and Saat, Jan and Dirding, Philipp}, title = {The Influence of Regulation on Data Warehouse Engineering - Investigating an IT Consulting Case in the Financial Service Industry}, series = {Proceedings of the Nineteenth Americas Conference on Information Systems, Chicago, Illinois, August 15-17, 2013.}, booktitle = {Proceedings of the Nineteenth Americas Conference on Information Systems, Chicago, Illinois, August 15-17, 2013.}, pages = {1 -- 8}, year = {2013}, language = {en} } @inproceedings{BeckerEggertSchwittay2012, author = {Becker, J{\"o}rg and Eggert, Mathias and Schwittay, Sebastian}, title = {How to Evaluate the Practical Relevance of Business Process Compliance Checking Approaches?}, series = {Multikonferenz Wirtschaftsinformatik 2012 - Tagungsband der MKWI 2012}, booktitle = {Multikonferenz Wirtschaftsinformatik 2012 - Tagungsband der MKWI 2012}, editor = {Mattfeld, Dirk Christian}, publisher = {Institut f{\"u}r Wirtschaftsinformatik}, address = {Braunschweig}, url = {http://nbn-resolving.de/urn:nbn:de:gbv:084-13011115376}, pages = {849 -- 862}, year = {2012}, language = {en} } @inproceedings{BeckerEggertWinkelmannetal.2011, author = {Becker, J{\"o}rg and Eggert, Mathias and Winkelmann, Axel and Knackstedt, Ralf}, title = {Towards a Contingency Theory based Model of the Influence of Regulation on MIS}, series = {Proceedings of the Seventeenth Americas Conference on Information Systems, Detroit, Michigan August 4th -7 th 2011}, booktitle = {Proceedings of the Seventeenth Americas Conference on Information Systems, Detroit, Michigan August 4th -7 th 2011}, year = {2011}, language = {en} } @article{BeckerFrauenrathHezeletal.2010, author = {Becker, Meike and Frauenrath, Tobias and Hezel, Fabian and Krombach, Gabriele A. and Kremer, Ute and Koppers, Benedikt and Butenweg, Christoph and Goemmel, Andreas and Utting, Jane F. and Schulz-Menger, Jeanette and Niendorf, Thoralf}, title = {Comparison of left ventricular function assessment using phonocardiogram- and electrocardiogram-triggered 2D SSFP CINE MR imaging at 1.5 T and 3.0 T}, series = {European Radiology}, volume = {20}, journal = {European Radiology}, publisher = {Springer}, address = {Berlin}, issn = {1432-1084 (Onlineausgabe)}, doi = {10.1007/s00330-009-1676-z}, pages = {1344 -- 1355}, year = {2010}, abstract = {Objective: As high-field cardiac MRI (CMR) becomes more widespread the propensity of ECG to interference from electromagnetic fields (EMF) and to magneto-hydrodynamic (MHD) effects increases and with it the motivation for a CMR triggering alternative. This study explores the suitability of acoustic cardiac triggering (ACT) for left ventricular (LV) function assessment in healthy subjects (n=14). Methods: Quantitative analysis of 2D CINE steady-state free precession (SSFP) images was conducted to compare ACT's performance with vector ECG (VCG). Endocardial border sharpness (EBS) was examined paralleled by quantitative LV function assessment. Results: Unlike VCG, ACT provided signal traces free of interference from EMF or MHD effects. In the case of correct Rwave recognition, VCG-triggered 2D CINE SSFP was immune to cardiac motion effects—even at 3.0 T. However, VCG-triggered 2D SSFP CINE imaging was prone to cardiac motion and EBS degradation if R-wave misregistration occurred. ACT-triggered acquisitions yielded LV parameters (end-diastolic volume (EDV), endsystolic volume (ESV), stroke volume (SV), ejection fraction (EF) and left ventricular mass (LVM)) comparable with those derived fromVCG-triggered acquisitions (1.5 T: ESVVCG=(56± 17) ml, EDVVCG=(151±32)ml, LVMVCG=(97±27) g, SVVCG=(94± 19)ml, EFVCG=(63±5)\% cf. ESVACT= (56±18) ml, EDVACT=(147±36) ml, LVMACT=(102±29) g, SVACT=(91± 22) ml, EFACT=(62±6)\%; 3.0 T: ESVVCG=(55±21) ml, EDVVCG=(151±32) ml, LVMVCG=(101±27) g, SVVCG=(96±15) ml, EFVCG=(65±7)\% cf. ESVACT=(54±20) ml, EDVACT=(146±35) ml, LVMACT= (101±30) g, SVACT=(92±17) ml, EFACT=(64±6)\%). Conclusions: ACT's intrinsic insensitivity to interference from electromagnetic fields renders}, language = {en} } @phdthesis{Beckmann2019, author = {Beckmann, Nils}, title = {Characterization of the hydrogen-dry-low-Nox-micromix-combustion-principle for hydrogen-methane fuel mixtures}, publisher = {RMIT University}, address = {Melbourne}, pages = {XV, 160 Seiten}, year = {2019}, language = {en} }