@article{KozhalakovaZhubanovaMansurovetal.2010,
  author    = {Kozhalakova, A. A. and Zhubanova, Azhar A. and Mansurov, Z. A. and Digel, Ilya and Tazhibayeva, S. M. and Artmann, Gerhard and Temiz Artmann, Ayseg{\"u}l},
  title     = {Adsorption of bacterial lipopolysaccharides on carbonized rice shell},
  series = {Science of Central Asia (2010)},
  journal   = {Science of Central Asia (2010)},
  pages     = {50 -- 54},
  year      = {2010},
  language  = {en}
}
@article{KraemerDaabMuelleretal.2013,
  author    = {Kr{\"a}mer, Stefan and Daab, Dominique Jonas and M{\"u}ller, Brigitte and Wagner, Tobias and Baader, Fabian and Hessel, Joana and Gdalewitsch, Georg and Plescher, Engelbert and Dachwald, Bernd and Wahle, Michael and Gierse, Andreas and Vetter, Rudolf and Pf{\"u}tzenreuter, Lysan},
  title     = {Development and flight-testing of a system to isolate vibrations for microgravity experiments on sounding rockets},
  series = {21st ESA Symposium on Rocket and Balloon Research},
  journal   = {21st ESA Symposium on Rocket and Balloon Research},
  pages     = {1 -- 8},
  year      = {2013},
  language  = {en}
}
@article{KuchlerGuenthnerRibeiroetal.2023,
  author    = {Kuchler, Timon and G{\"u}nthner, Roman and Ribeiro, Andrea and Hausinger, Renate and Streese, Lukas and W{\"o}hnl, Anna and Kesseler, Veronika and Negele, Johanna and Assali, Tarek and Carbajo-Lozoya, Javier and Lech, Maciej and Adorjan, Kristina and Stubbe, Hans Christian and Hanssen, Henner and Kotliar, Konstantin and Haller, Berhard and Heemann, Uwe and Schmaderer, Christoph},
  title     = {Persistent endothelial dysfunction in post-COVID-19 syndrome and its associations with symptom severity and chronic inflammation},
  volume    = {26},
  publisher = {Springer Nature},
  address   = {Dordrecht},
  doi       = {10.1007/s10456-023-09885-6},
  pages     = {547 -- 563},
  year      = {2023},
  abstract  = {Background Post-COVID-19 syndrome (PCS) is a lingering disease with ongoing symptoms such as fatigue and cognitive impairment resulting in a high impact on the daily life of patients. Understanding the pathophysiology of PCS is a public health priority, as it still poses a diagnostic and treatment challenge for physicians. Methods In this prospective observational cohort study, we analyzed the retinal microcirculation using Retinal Vessel Analysis (RVA) in a cohort of patients with PCS and compared it to an age- and gender-matched healthy cohort (n = 41, matched out of n = 204). Measurements and main results PCS patients exhibit persistent endothelial dysfunction (ED), as indicated by significantly lower venular flicker-induced dilation (vFID; 3.42\% ± 1.77\% vs. 4.64\% ± 2.59\%; p = 0.02), narrower central retinal artery equivalent (CRAE; 178.1 [167.5-190.2] vs. 189.1 [179.4-197.2], p = 0.01) and lower arteriolar-venular ratio (AVR; (0.84 [0.8-0.9] vs. 0.88 [0.8-0.9], p = 0.007). When combining AVR and vFID, predicted scores reached good ability to discriminate groups (area under the curve: 0.75). Higher PCS severity scores correlated with lower AVR (R = - 0.37 p = 0.017). The association of microvascular changes with PCS severity were amplified in PCS patients exhibiting higher levels of inflammatory parameters. Conclusion Our results demonstrate that prolonged endothelial dysfunction is a hallmark of PCS, and impairments of the microcirculation seem to explain ongoing symptoms in patients. As potential therapies for PCS emerge, RVA parameters may become relevant as clinical biomarkers for diagnosis and therapy management.},
  language  = {en}
}
@article{KuertenKotliarFuestetal.2021,
  author    = {Kuerten, David and Kotliar, Konstantin and Fuest, Matthias and Walter, Peter and Hollstein, Muriel and Plange, Niklas},
  title     = {Does hemispheric vascular regulation differ significantly in glaucoma patients with altitudinal visual field asymmetry? A single-center, prospective study},
  series = {International Ophthalmology},
  volume    = {41},
  journal   = {International Ophthalmology},
  number    = {41},
  editor    = {Neri, Piergiorgio},
  publisher = {Springer},
  address   = {Berlin},
  isbn      = {1573-2630},
  doi       = {10.1007/s10792-021-01876-0},
  pages     = {3109 -- 3119},
  year      = {2021},
  abstract  = {Purpose Vascular risk factors and ocular perfusion are heatedly discussed in the pathogenesis of glaucoma. The retinal vessel analyzer (RVA, IMEDOS Systems, Germany) allows noninvasive measurement of retinal vessel regulation. Significant differences especially in the veins between healthy subjects and patients suffering from glaucoma were previously reported. In this pilot-study we investigated if localized vascular regulation is altered in glaucoma patients with altitudinal visual field defect asymmetry. Methods 15 eyes of 12 glaucoma patients with advanced altitudinal visual field defect asymmetry were included. The mean defect was calculated for each hemisphere separately (-20.99 ± 10.49 pro- found hemispheric visual field defect vs -7.36 ± 3.97 dB less profound hemisphere). After pupil dilation, RVA measurements of retinal arteries and veins were conducted using the standard protocol. The superior and inferior retinal vessel reactivity were measured consecutively in each eye. Results Significant differences were recorded in venous vessel constriction after flicker light stimulation and overall amplitude of the reaction (p \ 0.04 and p \ 0.02 respectively) in-between the hemispheres spheres. Vessel reaction was higher in the hemisphere corresponding to the more advanced visual field defect. Arterial diameters reacted similarly, failing to reach statistical significance. Conclusion Localized retinal vessel regulation is significantly altered in glaucoma patients with asymmetri altitudinal visual field defects. Veins supplying the hemisphere concordant to a less profound visual field defect show diminished diameter changes. Vascular dysregulation might be particularly important in early glaucoma stages prior to a significant visual field defect.},
  language  = {en}
}
@article{KurulganDemirciDemirciTrzewiketal.2011,
  author    = {Kurulgan Demirci, Eylem and Demirci, T. and Trzewik, J{\"u}rgen and Linder, Peter and Karakulah, G. and Artmann, Gerhard and Sakizli, M. and Temiz Artmann, Ayseg{\"u}l},
  title     = {Genome-Wide Gene Expression Analysis of NIH 3T3 Cell Line Under Mechanical Stimulation},
  series = {Cellular and molecular bioengineering. 4 (2011), H. 1},
  journal   = {Cellular and molecular bioengineering. 4 (2011), H. 1},
  publisher = {Springer},
  address   = {Berlin},
  isbn      = {1865-5025},
  pages     = {46 -- 55},
  year      = {2011},
  language  = {en}
}
@article{KurulganDemirciDemirciLinderetal.2012,
  author    = {Kurulgan Demirci, Eylem and Demirci, Taylan and Linder, Peter and Trzewik, J{\"u}rgen and Gierkowski, Jessica Ricarda and Gossmann, Matthias and Kayser, Peter and Porst, Dariusz and Digel, Ilya and Artmann, Gerhard and Temiz Artmann, Ayseg{\"u}l},
  title     = {rhAPC reduces the endothelial cell permeability via a decrease of contractile tensions induced by endothelial cells},
  series = {Journal of Bioscience and Bioengineering},
  volume    = {113},
  journal   = {Journal of Bioscience and Bioengineering},
  number    = {2},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1347-4421},
  doi       = {10.1016/j.jbiosc.2012.03.019},
  pages     = {212 -- 219},
  year      = {2012},
  abstract  = {All cells generate contractile tension. This strain is crucial for mechanically controlling the cell shape, function and survival. In this study, the CellDrum technology quantifying cell's (the cellular) mechanical tension on a pico-scale was used to investigate the effect of lipopolysaccharide (LPS) on human aortic endothelial cell (HAoEC) tension. The LPS effect during gram-negative sepsis on endothelial cells is cell contraction causing endothelium permeability increase. The aim was to finding out whether recombinant activated protein C (rhAPC) would reverse the endothelial cell response in an in-vitro sepsis model. In this study, the established in-vitro sepsis model was confirmed by interleukin 6 (IL-6) levels at the proteomic and genomic levels by ELISA, real time-PCR and reactive oxygen species (ROS) activation by florescence staining. The thrombin cellular contraction effect on endothelial cells was used as a positive control when the CellDrum technology was applied. Additionally, the Ras homolog gene family, member A (RhoA) mRNA expression level was checked by real time-PCR to support contractile tension results. According to contractile tension results, the mechanical predominance of actin stress fibers was a reason of the increased endothelial contractile tension leading to enhanced endothelium contractility and thus permeability enhancement. The originality of this data supports firstly the basic measurement principles of the CellDrum technology and secondly that rhAPC has a beneficial effect on sepsis influenced cellular tension. The technology presented here is promising for future high-throughput cellular tension analysis that will help identify pathological contractile tension responses of cells and prove further cell in-vitro models.},
  language  = {en}
}
@article{KurulganDemirciLinderDemircietal.2009,
  author    = {Kurulgan Demirci, Eylem and Linder, Peter and Demirci, Taylan and Trzewik, J{\"u}rgen and Digel, Ilya and Artmann, Gerhard and Temiz Artmann, Ayseg{\"u}l},
  title     = {Contractile tension of endothelial cells: An LPS based in-vitro sepsis model},
  series = {IUBMB Life. 61 (2009), H. 3},
  journal   = {IUBMB Life. 61 (2009), H. 3},
  publisher = {Wiley},
  address   = {Weinheim},
  isbn      = {1521-6543},
  pages     = {307 -- 308},
  year      = {2009},
  language  = {en}
}
@article{KurzLinderTrzewiketal.2010,
  author    = {Kurz, R. and Linder, Peter and Trzewik, J{\"u}rgen and R{\"u}ffer, M. and Artmann, Gerhard and Digel, Ilya and Rothermel, A. and Robitzki, A. and Temiz Artmann, Ayseg{\"u}l},
  title     = {Contractile tension and beating rates of self-exciting monolayers and 3D-tissue constructs of neonatal rat cardiomyocytes},
  series = {Medical and Biological Engineering and Computing},
  volume    = {48},
  journal   = {Medical and Biological Engineering and Computing},
  number    = {1},
  publisher = {Springer Nature},
  address   = {Cham},
  issn      = {1741-0444},
  doi       = {10.1007/s11517-009-0552-y},
  pages     = {59 -- 65},
  year      = {2010},
  abstract  = {The CellDrum technology (The term 'CellDrum technology' includes a couple of slightly different technological setups for measuring lateral mechanical tension in various types of cell monolayers or 3D-tissue constructs) was designed to quantify the contraction rate and mechanical tension of self-exciting cardiac myocytes. Cells were grown either within flexible, circular collagen gels or as monolayer on top of respective 1-mum thin silicone membranes. Membrane and cells were bulged outwards by air pressure. This biaxial strain distribution is rather similar the beating, blood-filled heart. The setup allowed presetting the mechanical residual stress level externally by adjusting the centre deflection, thus, mimicking hypertension in vitro. Tension was measured as oscillating differential pressure change between chamber and environment. A 0.5-mm thick collagen-cardiac myocyte tissue construct induced after 2 days of culturing (initial cell density 2 x 10(4) cells/ml), a mechanical tension of 1.62 +/- 0.17 microN/mm(2). Mechanical load is an important growth regulator in the developing heart, and the orientation and alignment of cardiomyocytes is stress sensitive. Therefore, it was necessary to develop the CellDrum technology with its biaxial stress-strain distribution and defined mechanical boundary conditions. Cells were exposed to strain in two directions, radially and circumferentially, which is similar to biaxial loading in real heart tissues. Thus, from a biomechanical point of view, the system is preferable to previous setups based on uniaxial stretching.},
  language  = {en}
}
@article{KuehnHaugnerStaatetal.2004,
  author    = {K{\"u}hn, Raoul-Roman and Haugner, Werner and Staat, Manfred and Sponagel, Stefan},
  title     = {A Two Phase Mixture Model based on Bone Observation},
  year      = {2004},
  abstract  = {An optimization method is developed to describe the mechanical behaviour of the human cancellous bone. The method is based on a mixture theory. A careful observation of the behaviour of the bone material leads to the hypothesis that the bone density is controlled by the principal stress trajectories (Wolff's law). The basic idea of the developed method is the coupling of a scalar value via an eigenvalue problem to the principal stress trajectories. On the one hand this theory will permit a prediction of the reaction of the biological bone structure after the implantation of a prosthesis, on the other hand it may be useful in engineering optimization problems. An analytical example shows its efficiency.},
  subject      = {Knochen},
  language  = {en}
}
@article{LaackLeversStaat2013,
  author    = {Laack, Walter van and Levers, A. and Staat, Manfred},
  title     = {Gonarthrosetherapie auf Kernspinresonanzbasis mit MBST-Vierjahresbeobachtungen},
  series = {Orthop{\"a}dische Nachrichten : Zeitung f{\"u}r Orthop{\"a}die und Unfallchirurgie. 2013, H. 7/8},
  journal   = {Orthop{\"a}dische Nachrichten : Zeitung f{\"u}r Orthop{\"a}die und Unfallchirurgie. 2013, H. 7/8},
  publisher = {Biermann},
  address   = {K{\"o}ln},
  issn      = {1437-2193},
  pages     = {13},
  year      = {2013},
  language  = {de}
}
@article{LanzlKotliar2017,
  author    = {Lanzl, I. and Kotliar, Konstantin},
  title     = {K{\"o}nnen Anti-VEGF-Injektionen Glaukom oder okul{\"a}re Hypertension verursachen?},
  series = {Klinische Monatsbl{\"a}tter f{\"u}r Augenheilkunde},
  volume    = {234},
  journal   = {Klinische Monatsbl{\"a}tter f{\"u}r Augenheilkunde},
  number    = {2},
  publisher = {Thieme},
  address   = {Stuttgart},
  issn      = {0023-2165},
  doi       = {10.1055/s-0043-101819},
  pages     = {191 -- 193},
  year      = {2017},
  language  = {de}
}
@article{LanzlSeidovaErbenetal.2010,
  author    = {Lanzl, Ines M. and Seidova, Seid-Fatima and Erben, A. and Th{\"u}rmel, K. and Kotliar, Konstantin},
  title     = {Diffuse stromale Hornhauttr{\"u}bungen und Ver{\"a}nderungen der H{\"a}nde},
  series = {Der Ophthalmologe},
  volume    = {107},
  journal   = {Der Ophthalmologe},
  number    = {4},
  publisher = {Springer},
  address   = {Berlin},
  issn      = {1433-0423},
  doi       = {10.1007/s00347-009-2066-2},
  pages     = {363 -- 365},
  year      = {2010},
  abstract  = {Bilaterale stromale Hornhauttr{\"u}bungen sind f{\"u}r den Augenarzt eine differenzialdiagnostische Herausforderung. Im folgenden Beitrag werden 2 Patieninnen (30 und 36 Jahre) mit unterschiedlich stark ausgepr{\"a}gter stromaler diffuser Hornhauttr{\"u}bung vorgestellt. Patientin 1 war kleinw{\"u}chsig (114 cm) und Patientin 2 normal groß (172 cm). Beide Patientinnen wiesen ver{\"a}nderte Gelenkstrukturen an Hand und Fußgelenken sowie diffuse stromale Hornhauttr{\"u}bungen auf. Des Weiteren lagen eine Mitral- und Aorteninsuffizienz (Patientin 1) bzw. eine Aorteninsuffizienz (Patientin 2) vor. Die stromalen diffusen Hornhauttr{\"u}bungen ließen im Zusammenhang mit den Gelenkver{\"a}nderungen ein Scheie-Syndrom vermuten. Therapeutisch ist bei Patienten mit Visusminderung eine (lamell{\"a}re) Keratoplastik sinnvoll.},
  language  = {de}
}
@article{LanzlSeidovaMaieretal.2011,
  author    = {Lanzl, Ines M. and Seidova, Seid-Fatima and Maier, Mathias and Schmidt-Trucks{\"a}ss, Arno and Halle, Martin and Kotliar, Konstantin},
  title     = {Dynamic retinal vessel response to flicker in age-related macular degeneration patients before and after vascular endothelial growth factor inhibitor injection},
  series = {Acta Ophthalmologica},
  volume    = {89},
  journal   = {Acta Ophthalmologica},
  number    = {5},
  publisher = {Wiley},
  address   = {Weinheim},
  isbn      = {1755-3768},
  pages     = {472 -- 479},
  year      = {2011},
  language  = {en}
}
@article{LapitanRogatkinPersheyevetal.2018,
  author    = {Lapitan, Denis G. and Rogatkin, Dmitrii A. and Persheyev, Sydulla K. and Kotliar, Konstantin},
  title     = {False spectra formation in the differential two-channel scheme of the laser Doppler flowmeter},
  series = {Biomedizinische Technik},
  volume    = {63},
  journal   = {Biomedizinische Technik},
  number    = {4},
  publisher = {De Gruyter},
  address   = {Berlin},
  issn      = {0013-5585},
  doi       = {10.1515/bmt-2017-0060},
  pages     = {439 -- 444},
  year      = {2018},
  abstract  = {Noise in the differential two-channel scheme of a classic laser Doppler flowmetry (LDF) instrument was studied. Formation of false spectral components in the output signal due to beating of electrical signals in the differential amplifier was found out. The improved block-diagram of the flowmeter was developed allowing to reduce the noise.},
  language  = {en}
}
@article{LeimenaArtmannDachwaldetal.2010,
  author    = {Leimena, W. and Artmann, Gerhard and Dachwald, Bernd and Temiz Artmann, Ayseg{\"u}l and Gossmann, Matthias and Digel, Ilya},
  title     = {Feasibility of an in-situ microbial decontamination of an ice-melting probe},
  series = {Eurasian Chemico-Technological Journal. 12 (2010), H. 2},
  journal   = {Eurasian Chemico-Technological Journal. 12 (2010), H. 2},
  isbn      = {1562-3920},
  pages     = {145 -- 150},
  year      = {2010},
  language  = {en}
}
@article{LeipoldFichtnerHeberetal.2006,
  author    = {Leipold, M. and Fichtner, H. and Heber, B. and Groepper, P. and Lascar, S. and Burger, F. and Eiden, M. and Niederstadt, T. and Sickinger, C. and Herbeck, L. and Dachwald, Bernd and Seboldt, W.},
  title     = {Heliopause Explorer - A Sailcraft Mission to the Outer Boundaries of the Solar System},
  series = {Acta Astronautica. 59 (2006), H. 8-11},
  journal   = {Acta Astronautica. 59 (2006), H. 8-11},
  isbn      = {0094-5765},
  pages     = {786 -- 796},
  year      = {2006},
  language  = {en}
}
@article{LenzKahmannBehbahanietal.2022,
  author    = {Lenz, Maximilian and Kahmann, Stephanie Lucina and Behbahani, Mehdi and Pennig, Lenhard and Hackl, Michael and Leschinger, Tim and M{\"u}ller, Lars Peter and Wegmann, Kilian},
  title     = {Influence of rotator cuff preload on fracture configuration in proximal humerus fractures: a proof of concept for fracture simulation},
  series = {Archives of Orthopaedic and Trauma Surgery},
  journal   = {Archives of Orthopaedic and Trauma Surgery},
  publisher = {Springer},
  address   = {Berlin, Heidelberg},
  issn      = {1434-3916},
  doi       = {10.1007/s00402-022-04471-9},
  year      = {2022},
  abstract  = {Introduction In regard of surgical training, the reproducible simulation of life-like proximal humerus fractures in human cadaveric specimens is desirable. The aim of the present study was to develop a technique that allows simulation of realistic proximal humerus fractures and to analyse the influence of rotator cuff preload on the generated lesions in regards of fracture configuration. Materials and methods Ten cadaveric specimens (6 left, 4 right) were fractured using a custom-made drop-test bench, in two groups. Five specimens were fractured without rotator cuff preload, while the other five were fractured with the tendons of the rotator cuff preloaded with 2 kg each. The humeral shaft and the shortened scapula were potted. The humerus was positioned at 90° of abduction and 10° of internal rotation to simulate a fall on the elevated arm. In two specimens of each group, the emergence of the fractures was documented with high-speed video imaging. Pre-fracture radiographs were taken to evaluate the deltoid-tuberosity index as a measure of bone density. Post-fracture X-rays and CT scans were performed to define the exact fracture configurations. Neer's classification was used to analyse the fractures. Results In all ten cadaveric specimens life-like proximal humerus fractures were achieved. Two III-part and three IV-part fractures resulted in each group. The preloading of the rotator cuff muscles had no further influence on the fracture configuration. High-speed videos of the fracture simulation revealed identical fracture mechanisms for both groups. We observed a two-step fracture mechanism, with initial impaction of the head segment against the glenoid followed by fracturing of the head and the tuberosities and then with further impaction of the shaft against the acromion, which lead to separation of the tuberosities. Conclusion A high energetic axial impulse can reliably induce realistic proximal humerus fractures in cadaveric specimens. The preload of the rotator cuff muscles had no influence on initial fracture configuration. Therefore, fracture simulation in the proximal humerus is less elaborate. Using the presented technique, pre-fractured specimens are available for real-life surgical education.},
  language  = {en}
}
@article{LeschingerBeschAydinetal.2019,
  author    = {Leschinger, Tim and Besch, Katharina and Aydin, Cansu and Staat, Manfred and Scaal, Martin and M{\"u}ller, Lars Peter and Wegmann, Kilian},
  title     = {Irreparable rotator cuff tears: a biomechanical comparison of superior capsuloligamentous complex reconstruction techniques and an interposition graft technique},
  series = {The Orthopaedic Journal of Sports Medicine},
  volume    = {7},
  journal   = {The Orthopaedic Journal of Sports Medicine},
  number    = {8},
  doi       = {10.1177/2325967119864590},
  pages     = {1 -- 5},
  year      = {2019},
  language  = {en}
}
@article{LeschingerBirgelHackletal.2019,
  author    = {Leschinger, Tim and Birgel, Stefan and Hackl, Michael and Staat, Manfred and M{\"u}ller, Lars Peter and Wegmann, Kilian},
  title     = {A musculoskeletal shoulder simulation of moment arms and joint reaction forces after medialization of the supraspinatus footprint in rotator cuff repair},
  series = {Computer Methods in Biomechanics and Biomedical Engineering},
  journal   = {Computer Methods in Biomechanics and Biomedical Engineering},
  number    = {Early view},
  publisher = {Taylor \& Francis},
  address   = {London},
  doi       = {10.1080/10255842.2019.1572749},
  year      = {2019},
  language  = {en}
}
@article{LeversStaatLaack2011,
  author    = {Levers, A. and Staat, Manfred and Laack, Walter van},
  title     = {Analyse der Langzeitwirkung der MBST® KernspinResonanzTherapie bei Gonarthrose},
  year      = {2011},
  abstract  = {Originalausgabe: Orthop{\"a}dische Praxis Jg. 47. 2011 H. 11; S. 536-543. Mit freundlicher Genehmigung des Verlags Zusammenfassung: Auf der Basis von Patientenabfragen mittels Fragebogen zum Schmerzempfinden und zur Einschr{\"a}nkung bei Aktivit{\"a}ten des allt{\"a}glichen Lebens wird die Langzeitwirkung der MBST® KernspinResonanz-Therapie bei Gonarthrose untersucht. An der Studie nahmen 39 Patienten teil, bei denen die Therapie bis zu vier Jahre zur{\"u}ckliegt. Neben einer Gesamtbetrachtung wird der Erfolg auch in Abh{\"a}ngigkeit von Alter, Geschlecht und sportlicher Aktivit{\"a}t analysiert. Insgesamt weist die Studie auf eine anhaltende Verbesserung des Gesundheitszustands mit zum Teil deutlicher Schmerzlinderung auch noch nach vier Jahren hin, jedoch mit einer leichten Schmerzzunahme gegen Ende des Untersuchungszeitraums von vier Jahren. Eine tendenziell positivere Wirkung bei Frauen, {\"a}lteren Menschen oder auch sportlich nicht-aktiven Patienten l{\"a}sst auf eine m{\"o}gliche Beeinflussung des Erfolgs der Therapie durch ({\"U}ber-)Belastung im Alltag schließen. Ein zus{\"a}tzlich positiver Effekt der Therapie auf die Knochendichte ist ebenfalls denkbar, dies bleibt jedoch offen.},
  subject      = {Kniegelenkarthrose},
  language  = {de}
}
@article{LeversStaatLaack2016,
  author    = {Levers, A. and Staat, Manfred and Laack, Walter van},
  title     = {Analysis of the long-term effect of the MBST® nuclear magnetic resonance therapy on gonarthrosis},
  series = {Orthopedic Practice},
  volume    = {47},
  journal   = {Orthopedic Practice},
  number    = {11},
  pages     = {521 -- 528},
  year      = {2016},
  language  = {en}
}
@article{LindenFischoederLaacketal.2013,
  author    = {Linden, A. and Fisch{\"o}der, M. and Laack, Walter van and Staat, Manfred},
  title     = {Einschr{\"a}nkung von Taluskippung und -vorschub durch Sprunggelenkorthesen nach fibularer Bandruptur},
  series = {OUP Zeitschrift f{\"u}r die orthop{\"a}dische und unfallchirurgische Praxis},
  volume    = {2},
  journal   = {OUP Zeitschrift f{\"u}r die orthop{\"a}dische und unfallchirurgische Praxis},
  number    = {6},
  publisher = {Deutscher {\"A}rzte-Verl.},
  address   = {K{\"o}ln},
  isbn      = {2193-5785},
  doi       = {10.3238/oup.2013.0306-0309},
  pages     = {306 -- 309},
  year      = {2013},
  abstract  = {Die fibulare Bandruptur z{\"a}hlt zu einer der am h{\"a}ufigsten auftretenden Verletzungen des Bewegungsapparats. In den meisten F{\"a}llen wird heute die konservativ fr{\"u}hfunktionelle Therapie mit Sprunggelenkorthesen allgemein bevorzugt. Im Rahmen der vorliegenden Studie wurden 14 verschiedene Sprunggelenkorthesen im Hinblick auf ihre Einschr{\"a}nkung von Taluskippung und Talusvorschub untersucht. Zur Simulation einer fibularen Bandruptur wurde ein Unterschenkelmodell aus Holz mit Fußteil, mit angelegten Orthesen in einen Scheuba-Halteapparat eingespannt und mit 150 N seitlich sowie anterior-posterior belastet. Anhand der erstellten "gehaltenen" R{\"o}ntgenaufnahmen konnten Taluskippung und Talusvorschub jeder einzelnen Orthese eindeutig bestimmt werden. Die meisten Orthesen erreichten zufriedenstellende Ergebnisse. Es stellte sich heraus, dass vor allem eine eng anliegende, im Gelenkbereich anatomisch angepasste Form vorteilhaft zu sein scheint.},
  language  = {de}
}
@article{LinderBecklerDoerretal.2019,
  author    = {Linder, Peter and Beckler, Matthias and Doerr, Leo and Stoelzle-Feix, Sonja and Fertig, Niels and Jung, Alexander and Staat, Manfred and Gossmann, Matthias},
  title     = {A new in vitro tool to investigate cardiac contractility under physiological mechanical conditions},
  series = {Journal of Pharmacological and Toxicological Methods},
  volume    = {99},
  journal   = {Journal of Pharmacological and Toxicological Methods},
  number    = {Article number 106595},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1056-8719},
  doi       = {10.1016/j.vascn.2019.05.162},
  year      = {2019},
  language  = {en}
}
@article{LinderDigelTemizArtmannetal.2007,
  author    = {Linder, Peter and Digel, Ilya and Temiz Artmann, Ayseg{\"u}l and Kayser, Peter and Porst, Dariusz and Artmann, Gerhard},
  title     = {High-throughput testing of mechanical forces generated in thin cell and tissue layers},
  series = {Tissue Engineering. 13 (2007), H. 7},
  journal   = {Tissue Engineering. 13 (2007), H. 7},
  isbn      = {1076-3279},
  pages     = {1778 -- 1778},
  year      = {2007},
  language  = {en}
}
@article{LiphardtFernandezGonzaloAlbrachtetal.2023,
  author    = {Liphardt, Anna-Maria and Fernandez-Gonzalo, Rodrigo and Albracht, Kirsten and Rittweger, J{\"o}rn and Vico, Laurence},
  title     = {Musculoskeletal research in human space flight - unmet needs for the success of crewed deep space exploration},
  series = {npj Microgravity},
  volume    = {9},
  journal   = {npj Microgravity},
  number    = {Article number: 9},
  publisher = {Springer Nature},
  issn      = {2373-8065},
  doi       = {10.1038/s41526-023-00258-3},
  pages     = {1 -- 9},
  year      = {2023},
  abstract  = {Based on the European Space Agency (ESA) Science in Space Environment (SciSpacE) community White Paper "Human Physiology - Musculoskeletal system", this perspective highlights unmet needs and suggests new avenues for future studies in musculoskeletal research to enable crewed exploration missions. The musculoskeletal system is essential for sustaining physical function and energy metabolism, and the maintenance of health during exploration missions, and consequently mission success, will be tightly linked to musculoskeletal function. Data collection from current space missions from pre-, during-, and post-flight periods would provide important information to understand and ultimately offset musculoskeletal alterations during long-term spaceflight. In addition, understanding the kinetics of the different components of the musculoskeletal system in parallel with a detailed description of the molecular mechanisms driving these alterations appears to be the best approach to address potential musculoskeletal problems that future exploratory-mission crew will face. These research efforts should be accompanied by technical advances in molecular and phenotypic monitoring tools to provide in-flight real-time feedback.},
  language  = {en}
}
@article{LoebSchartnerDachwaldetal.2012,
  author    = {Loeb, Horst Wolfgang and Schartner, Karl-Heinz and Dachwald, Bernd and Ohndorf, Andreas and Seboldt, Wolfgang},
  title     = {Interstellar heliopause probe},
  series = {Труды МАИ},
  journal   = {Труды МАИ},
  number    = {60},
  publisher = {Moskauer Staatliches Luftfahrtinstitut (МАИ)},
  address   = {Moskau},
  pages     = {2 -- 2},
  year      = {2012},
  abstract  = {There is common agreement within the scientific community that in order to understand our local galactic environment it will be necessary to send a spacecraft into the region beyond the solar wind termination shock. Considering distances of 200 AU for a new mission, one needs a spacecraft traveling at a speed of close to 10 AU/yr in order to keep the mission duration in the range of less than 25 yrs, a transfer time postulated by European Space Agency (ESA). Two propulsion options for the mission have been proposed and discussed so far: the solar sail propulsion and the ballistic/radioisotope-electric propulsion (REP). As a further alternative, we here investigate a combination of solar-electric propulsion (SEP) and REP. The SEP stage consists of six 22-cms diameter RIT-22 ion thrusters working with a high specific impulse of 7377 s corresponding to a positive grid voltage of 5 kV. Solar power of 53 kW at begin of mission (BOM) is provided by a lightweight solar array.},
  language  = {en}
}
@article{LyonsMikuckiGermanetal.2019,
  author    = {Lyons, W. Berry and Mikucki, Jill A. and German, Laura A. and Welch, Kathleen A. and Welch, Susan A. and Gardener, Christopher B. and Tulaczyk, Slawek M. and Pettit, Erin C. and Kowalski, Julia and Dachwald, Bernd},
  title     = {The Geochemistry of Englacial Brine from Taylor Glacier, Antarctica},
  series = {Journal of Geophysical Research: Biogeosciences},
  journal   = {Journal of Geophysical Research: Biogeosciences},
  publisher = {Wiley},
  address   = {Hoboken},
  issn      = {2169-8961},
  doi       = {10.1029/2018JG004411},
  year      = {2019},
  language  = {en}
}
@article{MaggakisKelemenBorkKayseretal.2003,
  author    = {Maggakis-Kelemen, C. and Bork, M. and Kayser, Peter and Biselli, Manfred and Artmann, Gerhard},
  title     = {Biological and mechanical quality of red blood cells cultured from human umbilical cord blood stem cells},
  series = {Medical and biological engineering and computing. 41 (2003), H. 3},
  journal   = {Medical and biological engineering and computing. 41 (2003), H. 3},
  isbn      = {0140-0118},
  pages     = {350 -- 356},
  year      = {2003},
  language  = {en}
}
@article{MaggakisKelemenBiselliArtmann2002,
  author    = {Maggakis-Kelemen, Christina and Biselli, Manfred and Artmann, Gerhard},
  title     = {Determination of the elastic shear modulus of cultured human red blood cells},
  series = {Biomedizinische Technik. 47 (2002), H. Suppl. 1 Pt. 1},
  journal   = {Biomedizinische Technik. 47 (2002), H. Suppl. 1 Pt. 1},
  isbn      = {0013-5585},
  pages     = {106 -- 109},
  year      = {2002},
  language  = {en}
}
@article{MaggakisKelemenDigelArtmann2005,
  author    = {Maggakis-Kelemen, Christina and Digel, Ilya and Artmann, Gerhard},
  title     = {Polystyrene sulfonate/Polyallylamine hydrochloride microcapsules as potential artificial red blood cells - improvement of capsule flexibility},
  series = {Biomedizinische Technik. 50 (2005), H. Erg.-Bd. 1},
  journal   = {Biomedizinische Technik. 50 (2005), H. Erg.-Bd. 1},
  pages     = {324 -- 326},
  year      = {2005},
  language  = {en}
}
@article{MaierFeuchtWinklervonMohrenfelsetal.2011,
  author    = {Maier, M. M. and Feucht, N. and Winkler von Mohrenfels, C. and Kotliar, Konstantin and Fabian, E. and Lohmann, C. P.},
  title     = {Nahtlose Cerclage mit Skleratunnelfixation. Sutureless Encircling Band - Clinical Experience},
  series = {Klinische Monatsbl{\"a}tter f{\"u}r Augenheilkunde},
  volume    = {228},
  journal   = {Klinische Monatsbl{\"a}tter f{\"u}r Augenheilkunde},
  number    = {5},
  publisher = {Thieme},
  address   = {Stuttgart},
  isbn      = {0344-6360},
  pages     = {473 -- 476},
  year      = {2011},
  language  = {de}
}
@article{MaiwaldDachwald2010,
  author    = {Maiwald, Volker and Dachwald, Bernd},
  title     = {Mission Design for a Multiple-Rendezvous Mission to Jupiter's Trojans},
  pages     = {3},
  year      = {2010},
  language  = {en}
}
@article{MalanHamerKaeneletal.2020,
  author    = {Malan, Leone and Hamer, Mark and K{\"a}nel, Roland von and Kotliar, Konstantin and Wyk, Roelof D. van and Lambert, Gavin W. and Vilser, Walthard and Ziemssen, Tjalf and Schlaich, Markus P. and Smith, Wayne and Magnusson, Martin and Wentzel, Annemarie and Myburgh, Carlien E. and Steyn, Hendrik S. and Malan, Nico T.},
  title     = {Delayed retinal vein recovery responses indicate both non-adaptation to stress as well as increased risk for stroke: the SABPA study},
  series = {Cardiovascular Journal of Africa},
  volume    = {26},
  journal   = {Cardiovascular Journal of Africa},
  number    = {31},
  publisher = {Clinics Cardive Publishing},
  address   = {Durbanville},
  issn      = {1680-0745},
  doi       = {10.5830/CVJA-2020-031},
  pages     = {1 -- 12},
  year      = {2020},
  language  = {en}
}
@article{MalikAbdievaUalievaetal.2019,
  author    = {Malik, A. M. and Abdieva, G. Zh. and Ualieva, P. S. and Zhubanova, A. A. and Temiz Artmann, Ayseg{\"u}l},
  title     = {CКPИНИНГ МИКPOOPГAНИЗМOВ-ДECТPУКТOPOВ XЛOРOPГAНИЧECКИX ЗAГPЯЗНИТEЛEЙ},
  series = {Eurasian Journal of Ecology},
  volume    = {61},
  journal   = {Eurasian Journal of Ecology},
  number    = {4},
  issn      = {2617-7358},
  pages     = {61 -- 71},
  year      = {2019},
  language  = {ru}
}
@article{MalinowskiFournierHorbachetal.2022,
  author    = {Malinowski, Daniel and Fournier, Yvan and Horbach, Andreas and Frick, Michael and Magliani, Mirko and Kalverkamp, Sebastian and Hildinger, Martin and Spillner, Jan and Behbahani, Mehdi and Hima, Flutura},
  title     = {Computational fluid dynamics analysis of endoluminal aortic perfusion},
  series = {Perfusion},
  volume    = {0},
  journal   = {Perfusion},
  number    = {0},
  publisher = {Sage},
  address   = {London},
  issn      = {1477-111X},
  doi       = {10.1177/02676591221099809},
  pages     = {1 -- 8},
  year      = {2022},
  abstract  = {Introduction: In peripheral percutaneous (VA) extracorporeal membrane oxygenation (ECMO) procedures the femoral arteries perfusion route has inherent disadvantages regarding poor upper body perfusion due to watershed. With the advent of new long flexible cannulas an advancement of the tip up to the ascending aorta has become feasible. To investigate the impact of such long endoluminal cannulas on upper body perfusion, a Computational Fluid Dynamics (CFD) study was performed considering different support levels and three cannula positions. Methods: An idealized literature-based- and a real patient proximal aortic geometry including an endoluminal cannula were constructed. The blood flow was considered continuous. Oxygen saturation was set to 80\% for the blood coming from the heart and to 100\% for the blood leaving the cannula. 50\% and 90\% venoarterial support levels from the total blood flow rate of 6 l/min were investigated for three different positions of the cannula in the aortic arch. Results: For both geometries, the placement of the cannula in the ascending aorta led to a superior oxygenation of all aortic blood vessels except for the left coronary artery. Cannula placements at the aortic arch and descending aorta could support supra-aortic arteries, but not the coronary arteries. All positions were able to support all branches with saturated blood at 90\% flow volume. Conclusions: In accordance with clinical observations CFD analysis reveals, that retrograde advancement of a long endoluminal cannula can considerably improve the oxygenation of the upper body and lead to oxygen saturation distributions similar to those of a central cannulation.},
  language  = {en}
}
@article{MandekarHollandThielenetal.2022,
  author    = {Mandekar, Swati and Holland, Abigail and Thielen, Moritz and Behbahani, Mehdi and Melnykowycz, Mark},
  title     = {Advancing towards Ubiquitous EEG, Correlation of In-Ear EEG with Forehead EEG},
  series = {Sensors},
  volume    = {22},
  journal   = {Sensors},
  number    = {4},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {1424-8220},
  doi       = {10.3390/s22041568},
  pages     = {1 -- 19},
  year      = {2022},
  abstract  = {Wearable EEG has gained popularity in recent years driven by promising uses outside of clinics and research. The ubiquitous application of continuous EEG requires unobtrusive form-factors that are easily acceptable by the end-users. In this progression, wearable EEG systems have been moving from full scalp to forehead and recently to the ear. The aim of this study is to demonstrate that emerging ear-EEG provides similar impedance and signal properties as established forehead EEG. EEG data using eyes-open and closed alpha paradigm were acquired from ten healthy subjects using generic earpieces fitted with three custom-made electrodes and a forehead electrode (at Fpx) after impedance analysis. Inter-subject variability in in-ear electrode impedance ranged from 20 kΩ to 25 kΩ at 10 Hz. Signal quality was comparable with an SNR of 6 for in-ear and 8 for forehead electrodes. Alpha attenuation was significant during the eyes-open condition in all in-ear electrodes, and it followed the structure of power spectral density plots of forehead electrodes, with the Pearson correlation coefficient of 0.92 between in-ear locations ELE (Left Ear Superior) and ERE (Right Ear Superior) and forehead locations, Fp1 and Fp2, respectively. The results indicate that in-ear EEG is an unobtrusive alternative in terms of impedance, signal properties and information content to established forehead EEG.},
  language  = {en}
}
@article{MansurovJandosovKerimkulovaetal.2014,
  author    = {Mansurov, Z. A. and Jandosov, J. M. and Kerimkulova, A. R. and Azat, S. and Zhubanova, A. A. and Digel, Ilya and Savistkaya, I. S. and Akimbekov, N. S. and Kistaubaeva, A. S.},
  title     = {Nanostructured carbon materials for biomedical use},
  series = {Eurasian chemico-technological journal : quarterly journal of the International Higher Education Academy of Sciences},
  volume    = {15 (2013)},
  journal   = {Eurasian chemico-technological journal : quarterly journal of the International Higher Education Academy of Sciences},
  number    = {3},
  publisher = {Institute of Combustion Problems},
  address   = {Almaty},
  issn      = {1562-3920},
  doi       = {10.18321/ectj224},
  pages     = {209 -- 217},
  year      = {2014},
  abstract  = {One of the priority trends of carbon nanotechnology is creation of nanocomposite systems. Such carbon nanostructured composites were produced using - raw materials based on the products of agricultural waste, such as grape stones, apricot stones, rice husk. These products have a - wide spectrum of application and can be obtained in large quantities. The Institute of Combustion Problems has carried out the work on synthesis of the nanostructured carbon sorbents for multiple applications including the field of biomedicine. The article presents the data on the synthesis and physico-chemical properties of carbonaceous sorbents using physicochemical methods of investigation: separation and purification of biomolecules; isolation of phytohormone - fusicoccin; adsorbent INGO-1 in the form of an adsorption column for blood detoxification, oral (entero) sorbent - INGO-2; the study of efferent and probiotic properties and sorption activity in regard to the lipopolysaccharide (LPS), new biocomposites - based on carbonized rice husk (CRH) and cellular microorganisms; the use of CRH in wound treatment. A new material for blood detoxication (INGO-1) has been obtained. Adsorption of p-cresyl sulfate and indoxyl sulfate has shown that active carbon adsorbent can remove clinically significant level of p-cresyl sulfate and indoxyl sulfate from human plasma. Enterosorbent INGO-2 possesses high adsorption activity in relation to Gram-negative bacteria and their endotoxins. INGO-2 slows down the growth of conditionally pathogenic microorganisms, without having a negative effect on bifido and lactobacteria. The use of enterosorbent INGO-2 for sorption therapy may provide a solution to a complex problem - detoxication of the digestive tract and normalization of the intestinal micro ecology. The immobilized probiotic called "Riso-lact" was registered at the Ministry of Health of the Republic of Kazakhstan as a biologically active food additive. The developed technology is patented and provides production of the medicine in the form of freeze-dried biomass immobilized in vials.},
  language  = {en}
}
@article{MansurovDigelBiisenbaevetal.2012,
  author    = {Mansurov, Z. and Digel, Ilya and Biisenbaev, M. and Savistkaya, I. and Kistaubaeva, A. and Akimbekov, N. and Zhubanova, A.},
  title     = {Bio-composite material on the basis of carbonized rice husk in biomedicine and environmental applications},
  series = {Eurasian Chemico-Technological Journal},
  volume    = {14},
  journal   = {Eurasian Chemico-Technological Journal},
  number    = {2},
  publisher = {Institute of Combustion Problems},
  address   = {Almaty},
  issn      = {2522-4867},
  doi       = {10.18321/ectj105},
  pages     = {115 -- 131},
  year      = {2012},
  language  = {en}
}
@article{MartinGonzalezKotliarRiosMartinezetal.2014,
  author    = {Martin-Gonzalez, Anabel and Kotliar, Konstantin and Rios-Martinez, Jorge and Lanzl, Ines and Navab, Nassir},
  title     = {Mediated-reality magnification for macular degeneration rehabilitation},
  series = {Journal of Modern Optics},
  volume    = {61},
  journal   = {Journal of Modern Optics},
  number    = {17},
  publisher = {Taylor \& Francis},
  address   = {London},
  issn      = {1362-3044},
  doi       = {10.1080/09500340.2014.936110},
  pages     = {1400 -- 1408},
  year      = {2014},
  language  = {en}
}
@article{MenzelKotliarLanzl2009,
  author    = {Menzel, C. and Kotliar, Konstantin and Lanzl, I.},
  title     = {Retrospektive Untersuchung jahreszeitlich bedingter Einflussfaktoren auf den Augeninnendruck therapierter Glaukompatienten},
  series = {Der Ophthalmologe},
  volume    = {106},
  journal   = {Der Ophthalmologe},
  number    = {11},
  publisher = {-},
  isbn      = {1433-0423},
  pages     = {1006 -- 1011},
  year      = {2009},
  language  = {de}
}
@article{MeyerGaalenLeschingeretal.2019,
  author    = {Meyer, Carolin and Gaalen, Kerstin van and Leschinger, Tim and Scheyerer, Max J. and Neiss, Wolfram F. and Staat, Manfred and M{\"u}ller, Lars P. and Wegmann, Kilian},
  title     = {Kyphoplasty of Osteoporotic Fractured Vertebrae: A Finite Element Analysis about Two Types of Cement},
  series = {BioMed Research International},
  journal   = {BioMed Research International},
  doi       = {10.1155/2019/9232813},
  pages     = {Article ID 9232813},
  year      = {2019},
  language  = {en}
}
@article{MichaelMayerWeberetal.2017,
  author    = {Michael, Hackl and Mayer, Katharina and Weber, Mareike and Staat, Manfred and van Riet, Roger and Burkhart, Klau Josef and M{\"u}ller, Lars Peter and Wegmann, Kilian},
  title     = {Plate osteosynthesis of proximal ulna fractures : a biomechanical micromotion analysis},
  series = {The journal of hand surgery},
  volume    = {42},
  journal   = {The journal of hand surgery},
  number    = {10},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0363-5023},
  doi       = {10.1016/j.jhsa.2017.05.014},
  pages     = {834.e1 -- 834.e7},
  year      = {2017},
  language  = {en}
}
@article{MiciliValterOflazetal.2013,
  author    = {Micili, Serap C. and Valter, Markus and Oflaz, Hakan and Ozogul, Candan and Linder, Peter and F{\"o}ckler, Nicole and Artmann, Gerhard and Digel, Ilya and Temiz Artmann, Ayseg{\"u}l},
  title     = {Optical coherence tomography : a potential tool to predict premature rupture of fetal membranes},
  series = {Proceedings of the Institution of Mechanical Engineers. Part H : Journal of engineering in medicine},
  volume    = {Vol. 227},
  journal   = {Proceedings of the Institution of Mechanical Engineers. Part H : Journal of engineering in medicine},
  number    = {No. 4},
  publisher = {Sage},
  address   = {London},
  issn      = {0046-2039 (Print) ; 2041-3033 (E-Journal)},
  pages     = {393 -- 401},
  year      = {2013},
  language  = {en}
}
@article{MikielewiczKotliarBarraqueretal.2011,
  author    = {Mikielewicz, Marek and Kotliar, Konstantin and Barraquer, Rafael I. and Michael, Ralph},
  title     = {Air-pulse corneal applanation signal curve parameters for the characterisation of keratoconus},
  series = {British Journal of Ophthalmology (eBJO)},
  volume    = {95},
  journal   = {British Journal of Ophthalmology (eBJO)},
  number    = {6},
  publisher = {BMJ Publ. Group},
  address   = {London},
  issn      = {1468-2079},
  pages     = {793 -- 798},
  year      = {2011},
  language  = {en}
}
@article{MontiWaldvogelRitzmannetal.2021,
  author    = {Monti, Elena and Waldvogel, Janice and Ritzmann, Ramona and Freyler, Kathrin and Albracht, Kirsten and Helm, Michael and De Cesare, Niccol{\`o} and Pavan, Piero and Reggiani, Carlo and Gollhofer, Albert and Narici, Marco Vincenzo},
  title     = {Muscle in variable gravity: "I do not know where I am, but I know what to do"},
  series = {Frontiers in Physiology},
  volume    = {12},
  journal   = {Frontiers in Physiology},
  publisher = {Frontiers Research Foundation},
  address   = {Lausanne},
  issn      = {1664-042X},
  doi       = {10.3389/fphys.2021.714655},
  pages     = {19 Seiten},
  year      = {2021},
  abstract  = {Performing tasks, such as running and jumping, requires activation of the agonist and antagonist muscles before (motor unit pre-activation) and during movement performance (Santello and Mcdonagh, 1998). A well-timed and regulated muscle activation elicits a stretch-shortening cycle (SSC) response, naturally occurring in bouncing movements (Ishikawa and Komi, 2004; Taube et al., 2012). By definition, the SSC describes the stretching of a pre-activated muscle-tendon complex immediately followed by a muscle shortening in the concentric push-off phase (Komi, 1984). Given the importance of SSC actions for human movement, it is not surprising that many studies investigated the biomechanics of this phenomenon; in particular, drop jumps (DJs) represent a good paradigm to study muscle fascicle and tendon behavior in ballistic movements involving the SSC. Within a DJ, three main phases [pre-activation, braking, and push-off (PO; Komi, 2000)] have been recognized and extensively studied in common and challenging conditions, such as changes in load, falling height, or simulated hypo-gravity (Avela et al., 1994; Arampatzis et al., 2001; Fukashiro et al., 2005; Ishikawa et al., 2005; Sousa et al., 2007; Ritzmann et al., 2016; Helm et al., 2020). These studies show that the timing and amount of triceps-surae muscle-tendon unit pre-activation in DJs are differentially regulated based on the load applied to the muscle, being optimal in normal "Earth" gravity conditions (Avela et al., 1994), but decreased in simulated hypo-gravity, hyper-gravity (Avela et al., 1994; Ritzmann et al., 2016), or unknown conditions (i.e., unknown falling heights; Helm et al., 2020). Some authors indicated that, when falling from heights different from the optimal one [defined as the drop height giving a maximum DJ performance indicated as peak ground reaction force (GRF) or jump high], electromyographic (EMG) activity of the plantar flexors increases from lower than optimal to higher than optimal heights (Ishikawa and Komi, 2004; Sousa et al., 2007). These findings highlight the ability of the central nervous system to regulate the timing and amount of pre-activation according to different jumping conditions, thus regulating muscle fascicle length, tendon and joint stiffness as well as position, in order to safely land on the ground and quickly re-bounce. Similarly, to pre-activation, also in the braking phase, the plantar flexors are differentially regulated. In optimal height (i.e., load) jumping conditions, gastrocnemius medialis (GM) fascicles shorten at early ground contact (possibly due to the intervention of the stretch reflex; Gollhofer et al., 1992) and behave quasi-isometrically in the late braking phase, enabling tendon elongation, and storage of elastic energy (Gollhofer et al., 1992; Fukashiro et al., 2005; Sousa et al., 2007). When increasing the falling height (augmenting the impact GRF), the quasi-isometric behavior of fascicles disappears, and fast fascicle lengthening occurs (Ishikawa et al., 2005; Sousa et al., 2007). In the third and last PO phase, fascicles shorten and the tendon releases the elastic energy previously stored. Bobbert et al. (1987) reported no influence of jumping height on the work done and on the net vertical impulse assessed during PO; this observation suggests that, despite an optimal DJ performance might be achieved only in specific conditions (falling heights, loads), the central nervous system seems to be able to regulate muscle behavior in order to effectively perform the required task also in challenging situations. Although the regulation of triceps-surae muscle-tendon unit in DJs has been extensively investigated, very few studies focused on sarcomeres behavior during the performance of this SSC movement (Kurokawa et al., 2003; Fukashiro et al., 2005, 2006). Sarcomeres represent muscle contractile units and are known to express different amounts of force depending on their length (Gordon et al., 1966; Walker and Schrodt, 1974); thus, understanding the time course of their responses during DJs is fundamental to gain further insights into muscle force-generating capacity. In vivo measurement of sarcomere length in humans has been so far been performed only in static positions and under highly controlled experimental conditions (Llewellyn et al., 2008; Sanchez et al., 2015). Instead, human sarcomere length estimation (achieved by dividing GM measured fascicle length for a fixed sarcomere number) in dynamic contractions provided an indirect measure of sarcomere operating range during squat jump, countermovement jump, and DJ (Fukashiro et al., 2005, 2006; Kurokawa et al., 2003). The results of these studies showed that sarcomeres operate in the ascending limb of their length-tension (L-T) relationship in all types of jumps, and particularly so in DJ. However, most of the available observations on sarcomere and muscle fascicle behavior were made in condition of constant gravity. Thus, in order to understand how sarcomere and muscle fascicle length are regulated in variable gravity conditions, we performed experiments in a parabolic flight, involving variable gravity levels, ranging from about zero-g to about double the Earth's gravity (1 g; Waldvogel et al., 2021). Specifically, the aims of the present study were as follows: 1. To investigate the ability of the neuromuscular system in regulating fascicle length in response to conditions of variable gravity. 2. To estimate sarcomere operative length in the different DJ phases, in order to calculate its theoretical force production and its possible modulation in conditions of variable gravity. We hypothesized that muscle fascicles would be differentially regulated in different gravity conditions compared to 1 g, particularly in anticipation of landing and re-bouncing in unknown gravity levels. In addition, we hypothesized that sarcomeres would operate in the upper part of the ascending limb of their L-T relationship, possibly lengthening during the braking phase (especially in hyper-gravity) while operating quasi-isometrically in 1 g.},
  language  = {en}
}
@article{MoratFaudeHanssenetal.2020,
  author    = {Morat, Mareike and Faude, Oliver and Hanssen, Henner and Ludyga, Sebastian and Zacher, Jonas and Eibl, Angi and Albracht, Kirsten and Donath, Lars},
  title     = {Agility Training to Integratively Promote Neuromuscular, Cognitive, Cardiovascular and Psychosocial Function in Healthy Older Adults: A Study Protocol of a One-Year Randomized-Controlled Trial},
  series = {International Journal of Environmental Research and Public Health},
  volume    = {17},
  journal   = {International Journal of Environmental Research and Public Health},
  number    = {6},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {1660-4601},
  doi       = {10.3390/ijerph17061853},
  pages     = {1 -- 14},
  year      = {2020},
  abstract  = {Exercise training effectively mitigates aging-induced health and fitness impairments. Traditional training recommendations for the elderly focus separately on relevant physiological fitness domains, such as balance, flexibility, strength and endurance. Thus, a more holistic and functional training framework is needed. The proposed agility training concept integratively tackles spatial orientation, stop and go, balance and strength. The presented protocol aims at introducing a two-armed, one-year randomized controlled trial, evaluating the effects of this concept on neuromuscular, cardiovascular, cognitive and psychosocial health outcomes in healthy older adults. Eighty-five participants were enrolled in this ongoing trial. Seventy-nine participants completed baseline testing and were block-randomized to the agility training group or the inactive control group. All participants undergo pre- and post-testing with interim assessment after six months. The intervention group currently receives supervised, group-based agility training twice a week over one year, with progressively demanding perceptual, cognitive and physical exercises. Knee extension strength, reactive balance, dual task gait speed and the Agility Challenge for the Elderly (ACE) serve as primary endpoints and neuromuscular, cognitive, cardiovascular, and psychosocial meassures serve as surrogate secondary outcomes. Our protocol promotes a comprehensive exercise training concept for older adults, that might facilitate stakeholders in health and exercise to stimulate relevant health outcomes without relying on excessively time-consuming physical activity recommendations.},
  language  = {en}
}
@article{MurganBeyerKotliaretal.2013,
  author    = {Murgan, Ilina and Beyer, Sonja and Kotliar, Konstantin and Weber, Lutz and Bechtold-Dalla Pozza, Susanne and Dalla Pozza, Robert and Wegner, Aharon and Sitnikova, Diana and Stock, Konrad and Heemann, Uwe and Schmaderer, Christoph and Baumann, M.},
  title     = {Arterial and Retinal Vascular Changes in Hypertensive and Prehypertensive Adolescents},
  series = {American Journal of Hypertension},
  volume    = {26},
  journal   = {American Journal of Hypertension},
  number    = {3},
  publisher = {Oxford University Press},
  address   = {Oxford},
  issn      = {1941-7225},
  pages     = {400 -- 408},
  year      = {2013},
  language  = {de}
}
@article{MuellerJungAhammer2017,
  author    = {M{\"u}ller, Wolfram and Jung, Alexander and Ahammer, Helmut},
  title     = {Advantages and problems of nonlinear methods applied to analyze physiological time signals: human balance control as an example},
  series = {Scientific Reports},
  volume    = {7},
  journal   = {Scientific Reports},
  number    = {Article number 2464},
  publisher = {Springer Nature},
  address   = {Cham},
  isbn      = {2045-2322},
  doi       = {10.1038/s41598-017-02665-5},
  pages     = {1 -- 11},
  year      = {2017},
  language  = {en}
}
@article{NamAroraBehbahanietal.2010,
  author    = {Nam, J. and Arora, D. and Behbahani, Mehdi and Probst, M. and Benkowski, R. and Behr, M. and Pasquali, M.},
  title     = {New computational method in hemolysis analysis for artificial heart pump},
  year      = {2010},
  language  = {en}
}
@article{NeumaierKotliarHaerenetal.2021,
  author    = {Neumaier, Felix and Kotliar, Konstantin and Haeren, Roel Hubert Louis and Temel, Yasin and L{\"u}ke, Jan Niklas and Seyam, Osama and Lindauer, Ute and Clusmann, Hans and Hescheler, J{\"u}rgen and Schubert, Gerrit Alexander and Schneider, Toni and Albanna, Walid},
  title     = {Retinal Vessel Responses to Flicker Stimulation Are Impaired in Ca v 2.3-Deficient Mice—An in- vivo Evaluation Using Retinal Vessel Analysis (RVA)},
  series = {Frontiers in Neurology},
  volume    = {12},
  journal   = {Frontiers in Neurology},
  publisher = {Frontiers},
  doi       = {10.3389/fneur.2021.659890},
  pages     = {1 -- 11},
  year      = {2021},
  language  = {en}
}