@inproceedings{DuongNguyenStaat2012,
  author    = {Duong, Minh Tuan and Nguyen, Nhu Huynh and Staat, Manfred},
  title     = {Numerical stability enhancement of modeling hyperelastic materials},
  series = {Proceedings European Congress on Computational Methods in Applied Sciences and Engineering (ECCOMAS 2012)},
  booktitle = {Proceedings European Congress on Computational Methods in Applied Sciences and Engineering (ECCOMAS 2012)},
  editor    = {Eberhardsteiner, J.},
  year      = {2012},
  language  = {en}
}
@inproceedings{BeckerEggertHeddieretal.2012,
  author    = {Becker, J{\"o}rg and Eggert, Mathias and Heddier, Marcel and Knackstedt, Ralf},
  title     = {Merging Conceptual Modeling and Law for Legally Compliant Information Systems Design - A Framework-Based Research Agenda},
  series = {45th Hawaii International Conference on System Sciences 2012},
  booktitle = {45th Hawaii International Conference on System Sciences 2012},
  isbn      = {978-0-7695-4525-7},
  doi       = {10.1109/HICSS.2012.428},
  pages     = {5241 -- 5248},
  year      = {2012},
  language  = {en}
}
@inproceedings{BaumannTeixeiraBouraEcksteinetal.2012,
  author    = {Baumann, Torsten and Teixeira Boura, Cristiano Jos{\´e} and Eckstein, Julian and Dabrowski, Jan and G{\"o}ttsche, Joachim and Hoffschmidt, Bernhard and Schmitz, Stefan and Zunft, Stefan},
  title     = {Properties of bulk materials for high-temperature air-sand heat exchangers},
  series = {30th ISES Biennial Solar World Congress 2011 : Kassel, Germany, 28 August - 2 September 2011. Vol. 2},
  booktitle = {30th ISES Biennial Solar World Congress 2011 : Kassel, Germany, 28 August - 2 September 2011. Vol. 2},
  publisher = {Curran},
  address   = {Red Hook, NY},
  organization    = {International Solar Energy Society},
  isbn      = {978-1-61839-364-7},
  pages     = {1270 -- 1278},
  year      = {2012},
  language  = {en}
}
@inproceedings{BeckerEggertSchwittay2012,
  author    = {Becker, J{\"o}rg and Eggert, Mathias and Schwittay, Sebastian},
  title     = {How to Evaluate the Practical Relevance of Business Process Compliance Checking Approaches?},
  series = {Multikonferenz Wirtschaftsinformatik 2012 - Tagungsband der MKWI 2012},
  booktitle = {Multikonferenz Wirtschaftsinformatik 2012 - Tagungsband der MKWI 2012},
  editor    = {Mattfeld, Dirk Christian},
  publisher = {Institut f{\"u}r Wirtschaftsinformatik},
  address   = {Braunschweig},
  url       = {http://nbn-resolving.de/urn:nbn:de:gbv:084-13011115376},
  pages     = {849 -- 862},
  year      = {2012},
  language  = {en}
}
@article{BorgmeierBongaertsMeinhardt2012,
  author    = {Borgmeier, Claudia and Bongaerts, Johannes and Meinhardt, Friedhelm},
  title     = {Genetic analysis of the Bacillus licheniformis degSU operon and the impact of regulatory mutations on protease production},
  series = {Journal of biotechnology},
  volume    = {159},
  journal   = {Journal of biotechnology},
  number    = {1-2},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1873-4863 (E-Journal); 0168-1656 (Print)},
  doi       = {10.1016/j.jbiotec.2012.02.011},
  pages     = {12 -- 20},
  year      = {2012},
  abstract  = {Disruption experiments targeted at the Bacillus licheniformis degSU operon and GFP-reporter analysis provided evidence for promoter activity immediately upstream of degU. pMutin mediated concomitant introduction of the degU32 allele - known to cause hypersecretion in Bacillus subtilis - resulted in a marked increase in protease activity. Application of 5-fluorouracil based counterselection through establishment of a phosphoribosyltransferase deficient Δupp strain eventually facilitated the marker-free introduction of degU32 leading to further protease enhancement achieving levels as for hypersecreting wild strains in which degU was overexpressed. Surprisingly, deletion of rapG - known to interfere with DegU DNA-binding in B. subtilis - did not enhance protease production neither in the wild type nor in the degU32 strain. The combination of degU32 and Δupp counterselection in the type strain is not only equally effective as in hypersecreting wild strains with respect to protease production but furthermore facilitates genetic strain improvement aiming at biological containment and effectiveness of biotechnological processes.},
  language  = {en}
}
@inproceedings{WeilPoghossianSchoeningetal.2012,
  author    = {Weil, M. and Poghossian, Arshak and Sch{\"o}ning, Michael Josef and Cherstvy, A.},
  title     = {Electrical monitoring of layer-by-layer adsorption of oppositely charged macromolecules by means of capacitive field-effect devices},
  isbn      = {978-3-9813484-2-2},
  doi       = {10.5162/IMCS2012/P2.5.2},
  pages     = {1575 -- 1578},
  year      = {2012},
  language  = {en}
}
@article{HasanKeilStaatetal.2012,
  author    = {Hasan, Istabrak and Keil, Ludger and Staat, Manfred and Wahl, Gerhard and Bourauel, Christoph},
  title     = {Determination of the frictional coefficient of the implant-antler interface : experimental approach},
  series = {Biomedical Engineering / Biomedizinische Technik},
  volume    = {57},
  journal   = {Biomedical Engineering / Biomedizinische Technik},
  number    = {5},
  publisher = {De Gruyter},
  address   = {Berlin},
  issn      = {1862-278X},
  pages     = {359 -- 363},
  year      = {2012},
  abstract  = {The similar bone structure of reindeer antler to human bone permits studying the osseointegration of dental implants in the jawbone. As the friction is one of the major factors that have a significant influence on the initial stability of immediately loaded dental implants, it is essential to define the frictional coefficient of the implant-antler interface. In this study, the kinetic frictional forces at the implant-antler interface were measured experimentally using an optomechanical setup and a stepping motor controller under different axial loads and sliding velocities. The corresponding mean values of the static and kinetic frictional coefficients were within the range of 0.5-0.7 and 0.3-0.5, respectively. An increase in the frictional forces with increasing applied axial loads was registered. The measurements showed an evidence of a decrease in the magnitude of the frictional coefficient with increasing sliding velocity. The results of this study provide a considerable assessment to clarify the suitable frictional coefficient to be used in the finite element contact analysis of antler specimens.},
  language  = {en}
}
@inproceedings{TranStaat2012,
  author    = {Tran, Thanh Ngoc and Staat, Manfred},
  title     = {A primal-dual shakedown analysis of 3D structures using the face-based smoothed finite element method},
  series = {Proceedings European Congress on Computational Methods in Applied Sciences and Engineering (ECCOMAS 2012)},
  booktitle = {Proceedings European Congress on Computational Methods in Applied Sciences and Engineering (ECCOMAS 2012)},
  editor    = {Eberhardsteiner, J.},
  year      = {2012},
  language  = {en}
}
@article{PoghossianWeilBaeckeretal.2012,
  author    = {Poghossian, Arshak and Weil, M. H. and B{\"a}cker, Matthias and Mayer, D. and Sch{\"o}ning, Michael Josef},
  title     = {Field-effect Devices Functionalised with Gold-Nanoparticle/Macromolecule Hybrids: New Opportunities for a Label-Free Biosensing},
  series = {Procedia Engineering},
  journal   = {Procedia Engineering},
  number    = {47},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1877-7058},
  doi       = {10.1016/j.proeng.2012.09.136},
  pages     = {273 -- 276},
  year      = {2012},
  abstract  = {Field-effect capacitive electrolyte-insulator-semiconductor (EIS) sensors functionalised with citrate-capped gold nanoparticles (AuNP) have been used for the electrostatic detection of macromolecules by their intrinsic molecular charge. The EIS sensor detects the charge changes in the AuNP/macromolecule hybrids induced by the adsorption or binding events. A feasibility of the proposed detection scheme has been exemplary demonstrated by realising EIS sensors for the detection of poly-D-lysine molecules.},
  language  = {en}
}
@inproceedings{FrotscherRaatschenStaat2012,
  author    = {Frotscher, Ralf and Raatschen, Hans-J{\"u}rgen and Staat, Manfred},
  title     = {Effectiveness of the edge-based smoothed finite element method applied to soft biological tissues},
  series = {ESMC-2012 - 8th European Solid Mechanics Conference, Graz, Austria, July 9-13, 2012},
  booktitle = {ESMC-2012 - 8th European Solid Mechanics Conference, Graz, Austria, July 9-13, 2012},
  editor    = {Holzapfel, Gerhard A.},
  publisher = {Verlag d. Technischen Universit{\"a}t Graz},
  address   = {Graz},
  isbn      = {978-3-85125-223-1},
  year      = {2012},
  language  = {en}
}
@article{Weigand2012,
  author    = {Weigand, Christoph},
  title     = {Statistical Tests Based on Reliability and Precision},
  series = {Economic Quality Control : EQC ; international journal for quality and reliability},
  volume    = {27},
  journal   = {Economic Quality Control : EQC ; international journal for quality and reliability},
  number    = {1},
  publisher = {De Gruyter},
  address   = {Berlin},
  issn      = {1869-6147},
  doi       = {10.1515/eqc-2012-0002},
  pages     = {43 -- 64},
  year      = {2012},
  abstract  = {The construction of a statistical test is investigated which is based only on "reliability" and "precision" as quality criteria. The reliability of a statistical test is quantifiedin a straightforward way by the probability that the decision of the test is correct. However, the quantification of the precision of a statistical test is not at all evident. Thereforethe paper presents and discusses several approaches. Moreover the distinction of "nullhypothesis" and "alternative hypothesis" is not necessary any longer.},
  language  = {en}
}
@inproceedings{KnackstedtEggertFleischer2012,
  author    = {Knackstedt, Ralf and Eggert, Mathias and Fleischer, Stefan},
  title     = {The Legal Perspective on Business to Government Reporting - A Conceptual Modeling Approach and Its Application in the Financial Sector},
  series = {45th Hawaii International Conference on System Sciences 2012},
  booktitle = {45th Hawaii International Conference on System Sciences 2012},
  isbn      = {978-0-7695-4525-7},
  doi       = {10.1109/HICSS.2012.576},
  pages     = {2309 -- 2318},
  year      = {2012},
  language  = {en}
}
@article{SchoeningBiselliSelmeretal.2012,
  author    = {Sch{\"o}ning, Michael Josef and Biselli, Manfred and Selmer, Thorsten and {\"O}hlschl{\"a}ger, Peter and Baumann, Marcus and F{\"o}rster, Arnold and Poghossian, Arshak},
  title     = {Forschung „zwischen" den Disziplinen: das Institut f{\"u}r Nano- und Biotechnologien},
  series = {Analytik news : das Online-Labormagazin f{\"u}r Labor und Analytik},
  volume    = {Publ. online},
  journal   = {Analytik news : das Online-Labormagazin f{\"u}r Labor und Analytik},
  publisher = {Dr. Beyer Internet-Beratung},
  address   = {Ober-Ramstadt},
  pages     = {11 Seiten},
  year      = {2012},
  abstract  = {"Biologie trifft Mikroelektronik", das Motto des Instituts f{\"u}r Nano- und Biotechnologien (INB) an der FH Aachen, unterstreicht die zunehmende Bedeutung interdisziplin{\"a}r gepr{\"a}gter Forschungsaktivit{\"a}ten. Der thematische Zusammenschluss grundst{\"a}ndiger Disziplinen, wie die Physik, Elektrotechnik, Chemie, Biologie sowie die Materialwissenschaften, l{\"a}sst neue Forschungsgebiete entstehen, ein herausragendes Beispiel hierf{\"u}r ist die Nanotechnologie: Hier werden neue Werkstoffe und Materialien entwickelt, einzelne Nanopartikel oder Molek{\"u}le und deren Wechselwirkung untersucht oder Schichtstrukturen im Nanometerbereich aufgebaut, die neue und vorher nicht bekannte Eigenschaften hervorbringen. Vor diesem Hintergrund b{\"u}ndelt das im Jahre 2006 gegr{\"u}ndete INB die an der FH Aachen vorhandenen Kompetenzen von derzeit insgesamt sieben Laboratorien auf den Gebieten der Halbleitertechnik und Nanoelektronik, Nanostrukturen und DNA-Sensorik, der Chemo- und Biosensorik, der Enzymtechnologie, der Mikrobiologie und Pflanzenbiotechnologie, der Zellkulturtechnik, sowie der Roten Biotechnologie synergetisch. In der Nano- und Biotechnologie steckt außergew{\"o}hnliches Potenzial! Nicht zuletzt deshalb stellen sich die Forscher der Herausforderung, in diesem Bereich gemeinsam zu forschen und Schnittstellen zu nutzen, um so bei der Gestaltung neuartiger Ideen und Produkte mitzuwirken, die zuk{\"u}nftig unser allt{\"a}gliches Leben ver{\"a}ndern werden. Im Folgenden werden die verschiedenen Forschungsbereiche kurz zusammenfassend vorgestellt und vorhandene Interaktionen anhand von exemplarisch ausgew{\"a}hlten, aktuellen Forschungsprojekten skizziert.},
  language  = {de}
}
@article{SchusserPoghossianBaeckeretal.2012,
  author    = {Schusser, Sebastian and Poghossian, Arshak and B{\"a}cker, Matthias and Leinhos, Marcel and Wagner, Patrick and Sch{\"o}ning, Michael Josef},
  title     = {Characterization of biodegradable polymers with capacitive field-effect sensors},
  series = {Sensors and actuators B: Chemical},
  volume    = {187},
  journal   = {Sensors and actuators B: Chemical},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0925-4005},
  doi       = {10.1016/j.snb.2012.07.099},
  pages     = {2 -- 7},
  year      = {2012},
  abstract  = {In vitro studies of the degradation kinetic of biopolymers are essential for the design and optimization of implantable biomedical devices. In the presented work, a field-effect capacitive sensor has been applied for the real-time and in situ monitoring of degradation processes of biopolymers for the first time. The polymer-covered field-effect sensor is, in principle, capable to detect any changes in bulk, surface and interface properties of the polymer induced by degradation processes. The feasibility of this approach has been experimentally proven by using the commercially available biomedical polymer poly(D,L-lactic acid) (PDLLA) as a model system. PDLLA films of different thicknesses were deposited on the Ta₂O₅-gate surface of the field-effect structure from a polymer solution by means of spin-coating method. The polymer-modified field-effect sensors have been characterized by means of capacitance-voltage and impedance-spectroscopy method. The degradation of the PDLLA was accelerated by changing the degradation medium from neutral (pH 7.2) to alkaline (pH 9) condition, resulting in drastic changes in the capacitance and impedance spectra of the polymer-modified field-effect sensor.},
  language  = {en}
}
@article{BaeckerRaueSchusseretal.2012,
  author    = {B{\"a}cker, Matthias and Raue, Markus and Schusser, Sebastian and Jeitner, C. and Breuer, L. and Wagner, P. and Poghossian, Arshak and F{\"o}rster, Arnold and Mang, Thomas and Sch{\"o}ning, Michael Josef},
  title     = {Microfluidic chip with integrated microvalves based on temperature- and pH-responsive hydrogel thin films},
  series = {Physica Status Solidi (a)},
  volume    = {209},
  journal   = {Physica Status Solidi (a)},
  number    = {5},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {1862-6319},
  doi       = {10.1002/pssa.201100763},
  pages     = {839 -- 845},
  year      = {2012},
  abstract  = {Two types of microvalves based on temperature-responsive poly(N-isopropylacrylamide) (PNIPAAm) and pH-responsive poly(sodium acrylate) (PSA) hydrogel films have been developed and tested. The PNIPAAm and PSA hydrogel films were prepared by means of in situ photopolymerization directly inside the fluidic channel of a microfluidic chip fabricated by combining Si and SU-8 technologies. The swelling/shrinking properties and height changes of the PNIPAAm and PSA films inside the fluidic channel were studied at temperatures of deionized water from 14 to 36 °C and different pH values (pH 3-12) of Titrisol buffer, respectively. Additionally, in separate experiments, the lower critical solution temperature (LCST) of the PNIPAAm hydrogel was investigated by means of a differential scanning calorimetry (DSC) and a surface plasmon resonance (SPR) method. Mass-flow measurements have shown the feasibility of the prepared hydrogel films to work as an on-chip integrated temperature- or pH-responsive microvalve capable to switch the flow channel on/off.},
  language  = {en}
}
@inproceedings{AlexopoulosRauHoffschmidtetal.2012,
  author    = {Alexopoulos, Spiros and Rau, Christoph and Hoffschmidt, Bernhard and Breitbach, Gerd and Latzke, Markus},
  title     = {Modelling and validation of a transient heat recovery steam generator of the solar tower power plant Juelich},
  series = {Eurosun 2012 : Solar energy for a brighter future : conference proceedings : Rijeka, 18.-22.09.2012},
  booktitle = {Eurosun 2012 : Solar energy for a brighter future : conference proceedings : Rijeka, 18.-22.09.2012},
  address   = {Rijeka},
  pages     = {ID 97},
  year      = {2012},
  language  = {en}
}
@inproceedings{Anthrakidis2012,
  author    = {Anthrakidis, Anette},
  title     = {Pr{\"u}feinrichtung zur Bestimmung der Leistungsf{\"a}higkeit von solarthermischen Kollektoren bis 200 Grad C},
  series = {22. Symposium Thermische Solarenergie : 09. bis 11. Mai 2012, Kloster Banz, Bad Staffelstein},
  booktitle = {22. Symposium Thermische Solarenergie : 09. bis 11. Mai 2012, Kloster Banz, Bad Staffelstein},
  publisher = {OTTI},
  address   = {Regensburg},
  isbn      = {978-3-941785-89-2},
  pages     = {134 -- 135},
  year      = {2012},
  language  = {de}
}
@inproceedings{BungSunMeirelesetal.2012,
  author    = {Bung, Daniel Bernhard and Sun, Q. and Meireles, I. and Matos, J. and Viseu, T.},
  title     = {USBR type III stilling basin performance for steep stepped spillways},
  series = {Hydraulic structures into the 21st century : 4th IAHR International Symposium on Hydraulic Structures : 9.-11.2.2012, Porto},
  booktitle = {Hydraulic structures into the 21st century : 4th IAHR International Symposium on Hydraulic Structures : 9.-11.2.2012, Porto},
  organization    = {International Symposium on Hydraulic Structures <4, 2012, Porto>},
  isbn      = {978-989-8509-01-7},
  pages     = {Elektronisch publiziert},
  year      = {2012},
  language  = {en}
}
@inproceedings{OertelBung2012,
  author    = {Oertel, Mario and Bung, Daniel Bernhard},
  title     = {Characteristics of cross-bar block ramp flows},
  series = {Hydraulic structures into the 21st century : 4th IAHR International Symposium on Hydraulic Structures : 9.-11.2.2012, Porto},
  booktitle = {Hydraulic structures into the 21st century : 4th IAHR International Symposium on Hydraulic Structures : 9.-11.2.2012, Porto},
  organization    = {International Symposium on Hydraulic Structures <4, 2012, Porto>},
  isbn      = {978-989-8509-01-7},
  pages     = {Elektronisch publiziert},
  year      = {2012},
  language  = {en}
}
@inproceedings{SchlurmannBung2012,
  author    = {Schlurmann, Torsten and Bung, Daniel Bernhard},
  title     = {Experimental investigation of flow-induced radial gate vibrations at Lower Subansiri dam},
  series = {Sixth Chinese-German Joint Symposium on Hydraulic and Ocean Engineering : JOINT 2012 : 23.-29.9.2012, Keelung},
  booktitle = {Sixth Chinese-German Joint Symposium on Hydraulic and Ocean Engineering : JOINT 2012 : 23.-29.9.2012, Keelung},
  organization    = {Chinese-German Joint Symposium on Hydraulic and Ocean Engineering <6, 2012, Keelung>},
  pages     = {7 -- 14},
  year      = {2012},
  language  = {en}
}
@article{SchifferFerreinLakemeyer2012,
  author    = {Schiffer, Stefan and Ferrein, Alexander and Lakemeyer, Gerhard},
  title     = {Caesar: an intelligent domestic service robot},
  series = {Intelligent service robotics},
  volume    = {5},
  journal   = {Intelligent service robotics},
  number    = {4},
  publisher = {Springer},
  address   = {Berlin},
  issn      = {1861-2776},
  doi       = {10.1007/s11370-012-0118-y},
  pages     = {259 -- 276},
  year      = {2012},
  abstract  = {In this paper we present CAESAR, an intelligent domestic service robot. In domestic settings for service robots complex tasks have to be accomplished. Those tasks benefit from deliberation, from robust action execution and from flexible methods for human-robot interaction that account for qualitative notions used in natural language as well as human fallibility. Our robot CAESAR deploys AI techniques on several levels of its system architecture. On the low-level side, system modules for localization or navigation make, for instance, use of path-planning methods, heuristic search, and Bayesian filters. For face recognition and human-machine interaction, random trees and well-known methods from natural language processing are deployed. For deliberation, we use the robot programming and plan language READYLOG, which was developed for the high-level control of agents and robots; it allows combining programming the behaviour using planning to find a course of action. READYLOG is a variant of the robot programming language Golog. We extended READYLOG to be able to cope with qualitative notions of space frequently used by humans, such as "near" and "far". This facilitates human-robot interaction by bridging the gap between human natural language and the numerical values needed by the robot. Further, we use READYLOG to increase the flexible interpretation of human commands with decision-theoretic planning. We give an overview of the different methods deployed in CAESAR and show the applicability of a system equipped with these AI techniques in domestic service robotics},
  language  = {en}
}
@incollection{HoffschmidtAlexopoulosRauetal.2012,
  author    = {Hoffschmidt, Bernhard and Alexopoulos, Spiros and Rau, Christoph and Sattler, Johannes Christoph and Anthrakidis, Anette and Teixeira Boura, Cristiano Jos{\´e} and O'Connor, P. and Hilger, Patrick},
  title     = {Concentrating solar power},
  series = {Comprehensive renewable energy / ed. Ali Sayigh. Vol. 3: Solar thermal systems: components and applications},
  volume    = {3},
  booktitle = {Comprehensive renewable energy / ed. Ali Sayigh. Vol. 3: Solar thermal systems: components and applications},
  publisher = {Elsevier},
  address   = {Amsterdam},
  isbn      = {978-0-08-087872-0},
  doi       = {10.1016/B978-0-08-087872-0.00319-X},
  pages     = {595 -- 636},
  year      = {2012},
  language  = {en}
}
@article{BeckerDelfmannEggertetal.2012,
  author    = {Becker, J{\"o}rg and Delfmann, Patrick and Eggert, Mathias and Schwittay, Sebastian},
  title     = {Generalizability and Applicability of Model-Based Business Process Compliance-Checking Approaches — A State-of-the-Art Analysis and Research Roadmap},
  series = {Business Research : BuR},
  volume    = {5},
  journal   = {Business Research : BuR},
  number    = {2},
  publisher = {Springer},
  address   = {Heidelberg},
  issn      = {1866-8658},
  doi       = {10.1007/BF03342739},
  pages     = {221 -- 247},
  year      = {2012},
  abstract  = {With a steady increase of regulatory requirements for business processes, automation support of compliance management is a field garnering increasing attention in Information Systems research. Several approaches have been developed to support compliance checking of process models. One major challenge for such approaches is their ability to handle different modeling techniques and compliance rules in order to enable widespread adoption and application. Applying a structured literature search strategy, we reflect and discuss compliance-checking approaches in order to provide an insight into their generalizability and evaluation. The results imply that current approaches mainly focus on special modeling techniques and/or a restricted set of types of compliance rules. Most approaches abstain from real-world evaluation which raises the question of their practical applicability. Referring to the search results, we propose a roadmap for further research in model-based business process compliance checking.},
  language  = {en}
}
@incollection{LohseStroetmann2012,
  author    = {Lohse, Wolfram and Stroetmann, Richard},
  title     = {Stahlbau},
  series = {Wendehorst Bautechnische Zahlentafeln},
  booktitle = {Wendehorst Bautechnische Zahlentafeln},
  editor    = {Vismann, Ulrich},
  edition   = {34},
  publisher = {Vieweg + Teubner},
  address   = {Wiesbaden},
  isbn      = {978-3-8348-0960-5},
  doi       = {10.1007/978-3-8348-8613-2_13},
  pages     = {777 -- 1019},
  year      = {2012},
  language  = {de}
}
@inproceedings{OertelBungSchlenkhoff2012,
  author    = {Oertel, Mario and Bung, Daniel Bernhard and Schlenkhoff, Andreas},
  title     = {Blocksteinrampen in Riegelbauweise : Neue Bemessungsans{\"a}tze},
  series = {Staubauwerke : planen, bauen, betreiben; 35. Dresdner Wasserbaukolloquium 2012, 08. - 09. M{\"a}rz 2012},
  booktitle = {Staubauwerke : planen, bauen, betreiben; 35. Dresdner Wasserbaukolloquium 2012, 08. - 09. M{\"a}rz 2012},
  editor    = {Carstensen, Dirk},
  publisher = {Selbstverl. der Techn. Univ.},
  address   = {Dresden},
  organization    = {Technische Universit{\"a}t Dresden, Fakult{\"a}t Bauingenieurwesen},
  isbn      = {978-3-86780-261-1},
  pages     = {317 -- 326},
  year      = {2012},
  language  = {de}
}
@inproceedings{RitzTerhaarWallenborn2012,
  author    = {Ritz, Thomas and Terhaar, Kristin and Wallenborn, Ramona},
  title     = {HMI f{\"u}r eCarSharing : ein Baustein f{\"u}r nachhaltige Mobilit{\"a}t},
  series = {Mensch \& Computer 2012 - Workshopband : 12. Fach{\"u}bergreifende Konferenz f{\"u}r interaktive und kooperative Medien ; interaktiv informiert - allgegenw{\"a}rtig und allumfassend!?},
  booktitle = {Mensch \& Computer 2012 - Workshopband : 12. Fach{\"u}bergreifende Konferenz f{\"u}r interaktive und kooperative Medien ; interaktiv informiert - allgegenw{\"a}rtig und allumfassend!?},
  editor    = {Reiterer, Harald},
  publisher = {Oldenbourg},
  address   = {M{\"u}nchen},
  isbn      = {978-3-486-71990-1 (Print)},
  doi       = {10.1524/9783486719918.341},
  pages     = {381 -- 388},
  year      = {2012},
  language  = {de}
}
@article{Baehr2012,
  author    = {B{\"a}hr, Brigitte},
  title     = {[Gert Hoepner] im Interview zum Thema ; Verpackungspolitik - mehr als H{\"u}lle},
  series = {Packaging journal : Technologie, Logistik, Marketing, Produkte},
  journal   = {Packaging journal : Technologie, Logistik, Marketing, Produkte},
  number    = {5},
  publisher = {Ella Verlag},
  address   = {H{\"u}rth},
  issn      = {1610-0336},
  pages     = {78 -- 80},
  year      = {2012},
  language  = {de}
}
@article{LempiaeinenCouttetBolognanietal.2012,
  author    = {Lempi{\"a}inen, Harri and Couttet, Philippe and Bolognani, Federico and M{\"u}ller, Arne and Dubost, Val{\´e}rie and Luisier, Rapha{\"e}lle and Rio-Espinola, Alberto del and Vitry, Veronique and Unterberger, Elif B. and Thomson, John P. and Treindl, Fridolin and Metzger, Ute and Wrzodek, Clemens and Hahne, Florian and Zollinger, Tulipan and Brasa, Sarah and Kalteis, Magdalena and Marcellin, Magali and Giudicelli, Fanny and Braeuning, Albert and Morawiec, Laurent and Zamurovic, Natasa and L{\"a}ngle, Ulrich and Scheer, Nico and Sch{\"u}beler, Dirk and Goodman, Jay and Chibout, Salah-Dine and Marlowe, Jennifer and Theil, Dietlinde and Heard, David J. and Grenet, Olivier and Zell, Andreas and Templin, Markus F. and Meehan, Richard R. and Wolf, Roland C. and Elcombe, Clifford R. and Schwarz, Michael and Moulin, Pierre and Terranova, R{\´e}mi and Moggs, Jonathan G.},
  title     = {Identification of Dlk1-Dio3 imprinted gene cluster non-coding RNAs as novel candidate biomarkers for liver tumor promotion},
  series = {Toxicological Sciences},
  volume    = {131},
  journal   = {Toxicological Sciences},
  number    = {2},
  publisher = {Oxford University Press},
  address   = {Oxford},
  issn      = {1094-2025},
  doi       = {10.1093/toxsci/kfs303},
  pages     = {375 -- 386},
  year      = {2012},
  abstract  = {The molecular events during nongenotoxic carcinogenesis and their temporal order are poorly understood but thought to include long-lasting perturbations of gene expression. Here, we have investigated the temporal sequence of molecular and pathological perturbations at early stages of phenobarbital (PB) mediated liver tumor promotion in vivo. Molecular profiling (mRNA, microRNA [miRNA], DNA methylation, and proteins) of mouse liver during 13 weeks of PB treatment revealed progressive increases in hepatic expression of long noncoding RNAs and miRNAs originating from the Dlk1-Dio3 imprinted gene cluster, a locus that has recently been associated with stem cell pluripotency in mice and various neoplasms in humans. PB induction of the Dlk1-Dio3 cluster noncoding RNA (ncRNA) Meg3 was localized to glutamine synthetase-positive hypertrophic perivenous hepatocytes, sug- gesting a role for β-catenin signaling in the dysregulation of Dlk1-Dio3 ncRNAs. The carcinogenic relevance of Dlk1-Dio3 locus ncRNA induction was further supported by in vivo genetic dependence on constitutive androstane receptor and β-catenin pathways. Our data identify Dlk1-Dio3 ncRNAs as novel candidate early biomarkers for mouse liver tumor promotion and provide new opportunities for assessing the carcinogenic potential of novel compounds.},
  language  = {en}
}
@phdthesis{Bragard2012,
  author    = {Bragard, Michael},
  title     = {The integrated emitter turn-off thyristor : an innovative MOS-gated high-power device. - (Aachener Beitr{\"a}ge des ISEA ; 62)},
  publisher = {Shaker},
  address   = {Aachen},
  isbn      = {978-3-8440-1152-4},
  pages     = {III, 164 S. : Ill., graph. Darst.},
  year      = {2012},
  abstract  = {This thesis introduces the Integrated Emitter Turn-Off (IETO) Thyristor as a new high-power device. Known state-of-the-art research activities like the Dual GCT, the ETO thyristor and the ICT were presented and critically reviewed. A comparison with commercialized solutions identifies the pros and cons of each type of device family. Based on this analysis, the IETO structure is proposed, covering most benefits of each device class. In particular the combination of a MOS-assisted turn-off with a thyristor-based device allows a voltage-controlled MOS switching and the low on-state voltage of the thyristors. The following synthesis of an IETO device stands on a three-dimensional field of optimization spanned by electric, mechanical and thermal aspects. From an electric point of view, the lowest possible parasitic inductance and resistance within the commutation path are optimization criteria. The mechanical construction has to withstand the required contact pressure of multiple kilo Newtons. Finally, thermal borders limit the maximum average current of the device. FEM simulations covering these three aspects are performed for several design proposals. An IETO prototype is constructed and measurements on various test benches attest thermal, mechanical and electric performance. A local decoupling of the external driver stage and the presspack housing is presented by a cable connection. This separation enables a thermal and mechanical independence, which is advantageous in terms of vibrations and thermal cycles including increased reliability. The electric pulse performance of the prototype device is a factor of 3.1 above today''s solutions. In single-pulse measurements, a current up to 1600 A was successfully turned off at 115°C with an active silicon area of 823 mm². One reason for this increased turn-off capability is the extremely low-inductive construction. Additional functionality of the IETO thyristor like over-current self-protection and defined short-circuit failure state are successfully verified.},
  language  = {en}
}
@incollection{Fabo2012,
  author    = {Fabo, Sabine},
  title     = {Die Kunst der Irritation und ihr Mehrwert},
  series = {Vielen Dank f{\"u}r Ihren Einkauf : Konsumkultur aus Sicht von Design, Kunst und Medien},
  booktitle = {Vielen Dank f{\"u}r Ihren Einkauf : Konsumkultur aus Sicht von Design, Kunst und Medien},
  publisher = {Transcript Verlag},
  address   = {Bielefeld},
  isbn      = {978-3-8376-2170-9},
  pages     = {112 -- 145},
  year      = {2012},
  language  = {de}
}
@article{Wolf2012,
  author    = {Wolf, Martin R.},
  title     = {Von Security Awareness zum Secure Behaviour},
  series = {Hakin9 Extra - IT-Forensik},
  volume    = {2012},
  journal   = {Hakin9 Extra - IT-Forensik},
  number    = {5},
  publisher = {Software Wydawnictwo},
  address   = {Warszawa},
  issn      = {1733-7186},
  pages     = {18 -- 19},
  year      = {2012},
  abstract  = {Security Awareness ist derzeit ein viel diskutiertes Thema. Es reicht nicht, einfach nur ein paar technische Systeme (z.B. Firewalls) zu installieren, um ein angemessenes Schutzniveau zu erzielen. Neben einer guten Organisation von IT Security ist es auch notwendig, den Mitarbeiter einzubinden. Der vielzitierte "Faktor Mensch" ist derjenige, der die Technik korrekt anwenden muss und der durch falsches Verhalten technische und organisatorische Schutzmaßnahmen aushebeln kann. Deshalb reicht es nicht aus, wenn sich der Mitarbeiter der Gefahren bewusst ("aware") ist, er muss auch dementsprechend "sicher" handeln.},
  language  = {de}
}
@article{RiglingElkinDobbertinetal.2012,
  author    = {Rigling, Andreas and Elkin, Ch{\´e} and Dobbertin, Matthias and Eilmann, Britta and Giuggiola, Arnaud and Wohlgemuth, Thomas and Bugmann, Harald},
  title     = {Wald und Klimawandel in der inneralpinen Trockenregion Visp},
  series = {Schweizerische Zeitschrift f{\"u}r Forstwesen},
  volume    = {163},
  journal   = {Schweizerische Zeitschrift f{\"u}r Forstwesen},
  number    = {12},
  publisher = {Schweizerischer Forstverein},
  address   = {Z{\"u}rich},
  issn      = {2235-1469 (Online)},
  doi       = {10.3188/szf.2012.0481},
  pages     = {481 -- 492},
  year      = {2012},
  abstract  = {Der Temperaturanstieg der vergangenen Jahrzehnte war in Gebirgsregionen besonders ausgepr{\"a}gt. Sollte sich dieser Temperaturtrend im 21. Jahrhundert fortsetzen, dann d{\"u}rf-ten sich auch die H{\"a}ufigkeit und Intensit{\"a}t von Niederschl{\"a}-gen und Trockenperioden ver{\"a}ndern, was die Waldwirtschaft vor grosse Herausforderungen stellen wird. Trockenheit ist ein entscheidender Faktor f{\"u}r die Wald{\"o}kosysteme der inner-alpinen T{\"a}ler, wo seit Jahren trockenheitsbedingtes Baum-sterben festgestellt wird. Der vorliegende Beitrag hat zum Ziel, die Sensitivit{\"a}t der verschiedenen Wald{\"o}kosysteme ge-gen{\"u}ber Klimawandel und alternative, teilweise extreme Bewirtschaftungsvarianten in der Region Visp zu testen. Me-thodische Ans{\"a}tze wie Monitoring, Feldexperimente und dy-namische Modellierung wurden kombiniert, und es wurden verschiedene {\"O}kosystemleistungen ber{\"u}cksichtigt, so Holz-produktion, Schutz vor Naturgefahren, Kohlenstoffspeiche-rung und Aspekte der Biodiversit{\"a}t. Die Resultate deuten da-rauf hin, dass auf den Trockenstandorten der Tieflagen die einheimischen Baumarten an ihre physiologischen Grenzen stossen und l{\"a}ngerfristig {\"u}ber alternative Baumarten nach-gedacht werden sollte. In den mittleren Lagen d{\"u}rften Tro-ckenheit und Schadinsekten wie die Borkenk{\"a}fer die zuk{\"u}nf-tige Waldentwicklung steuern. In den Hochlagen hingegen werden sich die W{\"a}lder ausdehnen und besser wachsen als heute. Alle untersuchten {\"O}kosystemleistungen werden ge-bietsweise starken Ver{\"a}nderungen unterworfen sein. Die dis-kutierten Bewirtschaftungsvarianten scheinen dazu geeignet, die Wasserverf{\"u}gbarkeit der Best{\"a}nde, haupts{\"a}chlich in tief-eren Lagen, zu erh{\"o}hen und dadurch die Widerstandskraft der B{\"a}ume gegen{\"u}ber Trockenperioden vor{\"u}bergehend zu st{\"a}rken. Es ist aber davon ausgehen, dass nur verh{\"a}ltnism{\"a}s-sig starke Eingriffe wesentliche Effekte erzielen k{\"o}nnen. Die Verkn{\"u}pfung von Umweltmonitoring, Feldexperimenten und Modellierung unter Miteinbezug von {\"O}kosystemleistungen ist vielversprechend, da sie eine differenzierte Absch{\"a}tzung des zuk{\"u}nftigen Landschaftswandels und seiner Effekte auf die Waldleistungen erm{\"o}glicht.},
  language  = {de}
}
@misc{SchumannRoginSchneideretal.2012,
  author    = {Schumann, C. and Rogin, S. and Schneider, H. and Oster, J. and Tippk{\"o}tter, Nils and Kampeis, P.},
  title     = {Steuerung von HGMS-Prozessen mittels Durchflusszytometrie},
  series = {Chemie Ingenieur Technik},
  volume    = {84},
  journal   = {Chemie Ingenieur Technik},
  number    = {8},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {0009-286X},
  doi       = {10.1002/cite.201250125},
  pages     = {1370},
  year      = {2012},
  abstract  = {Die Hochgradientenmagnetseparation (HGMS) ist eine Methode zur Aufreinigung von biopharmazeutischen Produkten. Mit dieser Methode l{\"a}sst sich in nur einem Schritt eine Fest/Fest/Fl{\"u}ssig-Trennung erzielen, was zu einer erheblichen Zeit- und Kostenersparnis im Downstreaming f{\"u}hrt. Dennoch steht ihr industrieller Einsatz noch aus, was u. a. am Mangel an Analysenmethoden liegt, um die HGMS quantifizierbar zu machen. Gerade in der Pharmaproduktion werden Prozesse gebraucht, die gem{\"a}ß den einschl{\"a}gigen Vorschriften (cGMP) validiert und deren verfahrenstechnische Anlagenteile qualifiziert werden k{\"o}nnen. Die Schwierigkeit ist die Messung der magnetischen Mikrosorbentien in der Suspension, in der auch Zellen oder Zelltr{\"u}mmer vorliegen. Im Rahmen eines Forschungsprojektes im „Zentralen Innovationsprogramm Mittelstand" des BMWi wurden verschiedene Analysenmethoden untersucht. Die Durchflusszytometrie erm{\"o}glicht eine Charakterisierung von Partikeln und eine simultane quantitative Messung. Durch die multiparametrige Messung kann zwischen Zellen, Zelltr{\"u}mmern und Magnetpartikeln unterschieden werden. Die At-line-Einbindung des Durchflusszytometers ist durch den Einsatz einer externen Pumpe m{\"o}glich. {\"U}ber eine automatisierte Messwertanalyse kann der HGMS-Prozess mittels der Durchflusszytometrie gesteuert werden.},
  language  = {de}
}
@misc{LindelGreiserWaxmanetal.2012,
  author    = {Lindel, Tomasz Dawid and Greiser, Andreas and Waxman, Patrick and Dietterle, Martin and Seifert, Frank and Fontius, Ulrich and Renz, Wolfgang and Dieringer, Matthias A. and Frauenrath, Tobias and Schulz-Menger, Jeanette and Niendorf, Thoralf and Ittermann, Bernd},
  title     = {Cardiac CINE MRI at 7 T using a transmit array},
  series = {2012 ISMRM Annual Meeting Proceedings},
  journal   = {2012 ISMRM Annual Meeting Proceedings},
  issn      = {1545-4428},
  year      = {2012},
  abstract  = {With its need for high SNR and short acquisition times, Cardiac MRI (CMR) is an intriguing target application for ultrahigh field MRI. Due to the sheer size of the upper torso, however, the known RF issues of 7T MRI are also most prominent in CMR. Recent years brought substantial progress but the full potential of the ultrahigh field for CMR is yet to be exploited. Parallel transmission (pTx) is a promising approach in this context and several groups have already reported B1 shimming for 7T CMR. In such a static pTx application amplitudes and phases of all Tx channels are adjusted individually but otherwise imaging techniques established in current clinical practice 1.5 T and 3 T are applied. More advanced forms of pTx as spatially selective excitation (SSE) using Transmit SENSE promise additional benefits like faster imaging with reduced fields of view or improved SAR control. SSE requires the full dynamic capabilities of pTx, however, and for the majority of today's implemented pTx hardware the internal synchronization of the Tx array does not easily permit external triggering as needed for CMR. Here we report a software solution to this problem and demonstrate the feasibility of CINE CMR at 7 T using a Tx array.},
  language  = {en}
}
@incollection{Fabo2012,
  author    = {Fabo, Sabine},
  title     = {Einf{\"u}hrung},
  series = {Vielen Dank f{\"u}r Ihren Einkauf : Konsumkultur aus Sicht von Design, Kunst und Medien},
  booktitle = {Vielen Dank f{\"u}r Ihren Einkauf : Konsumkultur aus Sicht von Design, Kunst und Medien},
  publisher = {Transcript Verlag},
  address   = {Bielefeld},
  isbn      = {978-3-8376-2170-9},
  pages     = {9 -- 13},
  year      = {2012},
  language  = {de}
}
@article{FerreinMeyer2012,
  author    = {Ferrein, Alexander and Meyer, Thomas},
  title     = {A Brief Overview of Artificial Intelligence in South Africa},
  series = {AI Magazine},
  volume    = {33},
  journal   = {AI Magazine},
  number    = {1},
  publisher = {AAAI},
  address   = {Menlo Park},
  issn      = {0738-4602},
  doi       = {10.1609/aimag.v33i1.2357},
  pages     = {99 -- 101},
  year      = {2012},
  abstract  = {South Africa in recent years is the establishment of a number of research hubs involved in AI activities ranging from mobile robotics and computational intelligence, to knowledge representation and reasoning, and human language technologies. In this survey we take the reader through a quick tour of the research being conducted at these hubs, and touch on an initiative to maintain and extend the current level of interest in AI research in the country.},
  language  = {en}
}
@article{BragardvanHoekDeDoncker2012,
  author    = {Bragard, Michael and van Hoek, H. and De Doncker, R. W.},
  title     = {A major design step in IETO concept realization that allows overcurrent protection and pushes limits of switching performance},
  series = {IEEE transactions on power electronics},
  volume    = {27},
  journal   = {IEEE transactions on power electronics},
  number    = {9},
  publisher = {IEEE},
  address   = {New York},
  issn      = {0885-8993},
  doi       = {10.1109/TPEL.2012.2189136},
  pages     = {4163 -- 4171},
  year      = {2012},
  abstract  = {This paper presents the latest prototype of the integrated emitter turn-off thyristor concept, which potentially ranks among thyristor high-power devices like the gate turn-off thyristor and the integrated gate-commutated thyristor (IGCT). Due to modifications of the external driver stage and mechanical press-pack design optimization, this prototype allows for full device characterization. The turn-off capability was increased to 1600 A with an active silicon area of 823mm2 . This leads to a transient peak power of 672.1kW/cm² . Within this paper, measurements and concept assessment are presented and a comparison to state-of-the-art IGCT devices is provided.},
  language  = {en}
}
@misc{TippkoetterUlber2012,
  author    = {Tippk{\"o}tter, Nils and Ulber, Roland},
  title     = {Rezension zu: Encyclopedia of Industrial Biotechnology, Vol. 1-7. By MC Flickinger.},
  series = {Chemie Ingenieur Technik},
  volume    = {6},
  journal   = {Chemie Ingenieur Technik},
  number    = {84},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {0009-286X},
  doi       = {10.1002/cite.201290052},
  pages     = {936},
  year      = {2012},
  language  = {en}
}
@misc{TippkoetterStaubSohlingetal.2012,
  author    = {Tippk{\"o}tter, Nils and Staub, C. and Sohling, U. and Ruf, N. and Ulber, Roland},
  title     = {Adsorptive Aufreinigung von Molkeproteinen},
  series = {Chemie Ingenieur Technik},
  volume    = {84},
  journal   = {Chemie Ingenieur Technik},
  number    = {8},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {0009-286X},
  doi       = {10.1002/cite.201250395},
  pages     = {1285},
  year      = {2012},
  abstract  = {In der Molkeverarbeitung dominieren Membranfiltrationsverfahren die Prozessf{\"u}hrung. Hierbei werden {\"u}blicherweise Aufkonzentrierungen der Proteine und deren Trennung von dem Milchzucker Lactose durchgef{\"u}hrt. Der Prozess der adsorptiven Aufreinigung soll als kosteng{\"u}nstige Alternative zu den bisher gebr{\"a}uchlichen Verfahren dienen. Weiterhin er{\"o}ffnet sich durch das Verfahren die M{\"o}glichkeit, einzelne Proteinfraktionen w{\"a}hrend der Verarbeitung anzureichern. Als Proteinquellen wurden f{\"u}r die Untersuchungen Modellproteine, L{\"o}sungen aus Molkenproteinisolat, D{\"u}nnmolke und Molkekonzentrat verwendet. Die Eignung zur Proteinbindung wurden an Tonmaterialien, Silicaten und y-Aluminiumoxiden in Pulverform, in Form von Granulaten sowie Extrudaten als auch sph{\"a}rischen Partikeln {\"u}berpr{\"u}ft. Adsorbentien aus Bentonit/Silica und c-Aluminiumoxid k{\"o}nnen sowohl a-Lactalbumin (aLA) als auch b-Lactoglobulin (bLG) binden, wohingegen Materialien aus Siliciumoxid lediglich ein starkes Adsorptionsverhalten gegen{\"u}ber bLG zeigen. Mischmaterialien aus Siliciumoxid und a-Aluminiumoxid zeigen dasselbe Verhalten wie Materialien aus Siliciumoxid, weisen jedoch eine geringere Kapazit{\"a}t auf. Die Materialen wurden hinsichtlich ihres Einsatzes in chromatographischen Verfahren und Batch-Prozessen untersucht und ein Prozessentwurf f{\"u}r einen zweistufigen Batch-Prozess im R{\"u}hrkessel erarbeitet.},
  language  = {de}
}
@incollection{Fabo2012,
  author    = {Fabo, Sabine},
  title     = {Gef{\"a}hrliche Liebschaften : Kunst zwischen Wderstand und Umarmung},
  series = {Interventionen : Grenz{\"u}berschreitungen in {\"A}sthetik, Politik und {\"O}konomie},
  booktitle = {Interventionen : Grenz{\"u}berschreitungen in {\"A}sthetik, Politik und {\"O}konomie},
  editor    = {Hartmann, Doreen and [u.a.],},
  publisher = {Fink},
  address   = {M{\"u}nchen [u.a.]},
  isbn      = {978-3-7705-5283-2},
  pages     = {173 -- 189},
  year      = {2012},
  language  = {de}
}
@misc{TkachenkovonKnobelsdorffBrenkenhoffKleindienstetal.2012,
  author    = {Tkachenko, Valeriy and von Knobelsdorff-Brenkenhoff, Florian and Kleindienst, Denise and Winter, Lukas and Rieger, Jan and Frauenrath, Tobias and Dieringer, Matthias A. and Santoro, Davide and Niendorf, Thoralf and Schulz-Menger, Jeanette},
  title     = {Cardiovasular MR at 7Tesla: assessment of the right ventricle},
  series = {2012 ISMRM Annual Meeting Proceedings},
  journal   = {2012 ISMRM Annual Meeting Proceedings},
  issn      = {1545-4428},
  year      = {2012},
  abstract  = {The assessment of the right ventricle (RV) is a challenge in today's cardiology, but of growing clinical impact regarding patient prognosis in different cardiac diseases. The detection and differentiation of small wall motion abnormalities may help to enhance the differentiation of cardiomyopathies including Arrhythmogenic Rightventricular Cardiomyopathy. Cardiovascular magnetic resonance (CMR) at 1.5T is the accepted gold standard for RV quantification. The higher spatial resolution achievable at ultrahigh field strength (UHF) offers the potential to gain new insights into the structure and function of the RV. To approach this goal accurate RV chamber quantification at 7T has to be proven. Consequently this study examines the feasibility of assessment of RV dimensions and function at 7T using improved spatial resolution enabled by the intrinsic sensitivity gain of UHF CMR. For this purpose, a dedicated 16 channel TX/RX RF coil array is used together with 2D CINE fast gradient echo (FGRE) imaging. For comparison RV chamber quantification is conducted at 1.5T using a SSFP based state of the art clinical protocol.},
  language  = {en}
}
@article{ScheerBalimaneHaywardetal.2012,
  author    = {Scheer, Nico and Balimane, Praveen and Hayward, Michael D. and Buechel, Sandra and Kauselmann, Gunther and Wolf, C. Roland},
  title     = {Generation and Characterization of a Novel Multidrug Resistance Protein 2 Humanized Mouse Line},
  series = {Drug Metabolism and Disposition},
  volume    = {40},
  journal   = {Drug Metabolism and Disposition},
  number    = {11},
  publisher = {ASPET},
  address   = {Bethesda, Md.},
  issn      = {1521-0111},
  doi       = {10.1124/dmd.112.047605},
  pages     = {2212 -- 2218},
  year      = {2012},
  abstract  = {The multidrug resistance protein (MRP) 2 is predominantly expressed in liver, intestine, and kidney, where it plays an important role in the excretion of a range of drugs and their metabolites or endogenous compounds into bile, feces, and urine. Mrp knockout [Mrp2(-/-)] mice have been used recently to study the role of MRP2 in drug disposition. Here, we describe the first generation and initial characterization of a mouse line humanized for MRP2 (huMRP2), which is nulled for the mouse Mrp2 gene and expresses the human transporter in the organs and cell types where MRP2 is normally expressed. Analysis of the mRNA expression for selected cytochrome P450 and transporter genes revealed no major changes in huMRP2 mice compared with wild-type controls. We show that human MRP2 is able to compensate functionally for the loss of the mouse transporter as demonstrated by comparable bilirubin levels in the humanized mice and wild-type controls, in contrast to the hyperbilirubinemia phenotype that is observed in MRP2(-/-) mice. The huMRP2 mouse provides a model to study the role of the human transporter in drug disposition and in assessing the in vivo consequences of inhibiting this transporter by compounds interacting with human MRP2.},
  language  = {en}
}
@misc{GraesslRenzHezeletal.2012,
  author    = {Gr{\"a}ßl, Andreas and Renz, Wolfgang and Hezel, Fabian and Frauenrath, Tobias and Pfeiffer, Harald and Hoffmann, Werner and Kellmann, Peter and Martin, Conrad and Niendorf, Thoralf},
  title     = {Design, evaluation and application of a modular 32 channel transmit/receive surface coil array for cardiac MRI at 7T},
  series = {2012 ISMRM Annual Meeting Proceedings},
  journal   = {2012 ISMRM Annual Meeting Proceedings},
  issn      = {1545-4428},
  year      = {2012},
  abstract  = {Cardiac MR (CMR) at ultrahigh (≥7.0 T) fields is regarded as one of the most challenging MRI applications. At 7.0 T image quality is not always exclusively defined by signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR). Detrimental effects bear the potential to spoil the signal-to-noise (SNR) and contrast-to-noise (CNR) benefits of cardiac MR (CMR) at 7.0 T. B₁⁺-inhomogeneities and signal voids represent the main challenges. Various pioneering coil concepts have been proposed to tackle these issues, enabling cardiac MRI at 7.0 T. This includes a trend towards an ever larger number of transmit and receive channels. This approach affords multi-dimensional B₁⁺ modulations to improve B₁⁺ shimming performance and to enhance RF efficiency. Also, parallel imaging benefits from a high number of receive channels enabling two-dimensional acceleration. Realizing the limitations of existing coil designs tailored for UHF CMR and recognizing the opportunities of a many element TX/RX channel architecture this work proposes a modular, two dimensional 32-channel transmit and receive array using loop elements and examines its efficacy for enhanced B¹+ homogeneity and improved parallel imaging performance.},
  language  = {en}
}
@article{FrauenrathFuchsDieringeretal.2012,
  author    = {Frauenrath, Tobias and Fuchs, Katharina and Dieringer, Matthias A. and {\"O}zerdem, Celal and Patel, Nishan and Renz, Wolfgang and Greiser, Andreas and Elgeti, Thomas and Niendorf, Thoralf},
  title     = {Detailing the use of magnetohydrodynamic effects for synchronization of MRI with the cardiac cycle: A feasibility study},
  series = {Journal of Magnetic Resonance Imaging},
  volume    = {36},
  journal   = {Journal of Magnetic Resonance Imaging},
  number    = {2},
  publisher = {Wiley-Liss},
  address   = {New York},
  issn      = {1522-2586},
  doi       = {10.1002/jmri.23634},
  pages     = {364 -- 372},
  year      = {2012},
  abstract  = {Purpose: To investigate the feasibility of using magnetohydrodynamic (MHD) effects for synchronization of magnetic resonance imaging (MRI) with the cardiac cycle. Materials and Methods: The MHD effect was scrutinized using a pulsatile flow phantom at B0 = 7.0 T. MHD effects were examined in vivo in healthy volunteers (n = 10) for B0 ranging from 0.05-7.0 T. Noncontrast-enhanced MR angiography (MRA) of the carotids was performed using a gated steady-state free-precession (SSFP) imaging technique in conjunction with electrocardiogram (ECG) and MHD synchronization. Results: The MHD potential correlates with flow velocities derived from phase contrast MRI. MHD voltages depend on the orientation between B0 and the flow of a conductive fluid. An increase in the interelectrode spacing along the flow increases the MHD potential. In vivo measurement of the MHD effect provides peak voltages of 1.5 mV for surface areas close to the common carotid artery at B0 = 7.0 T. Synchronization of MRI with the cardiac cycle using MHD triggering is feasible. MHD triggered MRA of the carotids at 3.0 T showed an overall image quality and richness of anatomic detail, which is comparable to ECG-triggered MRAs. Conclusion: This feasibility study demonstrates the use of MHD effects for synchronization of MR acquisitions with the cardiac cycle. J. Magn. Reson. Imaging 2012;36:364-372. © 2012 Wiley Periodicals, Inc.},
  language  = {en}
}
@article{EilmannRigling2012,
  author    = {Eilmann, Britta and Rigling, Andreas},
  title     = {Tree-growth analyses to estimate tree species' drought tolerance},
  series = {Tree Physiology},
  volume    = {32},
  journal   = {Tree Physiology},
  number    = {2},
  editor    = {Abrams, Marc},
  publisher = {Oxford University Press},
  address   = {Oxford},
  issn      = {0829-318X (Print)},
  doi       = {10.1093/treephys/tps004},
  pages     = {178 -- 187},
  year      = {2012},
  abstract  = {Climate change is challenging forestry management and practices. Among other things, tree species with the ability to cope with more extreme climate conditions have to be identified. However, while environmental factors may severely limit tree growth or even cause tree death, assessing a tree species' potential for surviving future aggravated environmental conditions is rather demanding. The aim of this study was to find a tree-ring-based method suitable for identifying very drought-tolerant species, particularly potential substitute species for Scots pine (Pinus sylvestris L.) in Valais. In this inner-Alpine valley, Scots pine used to be the dominating species for dry forests, but today it suffers from high drought-induced mortality. We investigate the growth response of two native tree species, Scots pine and European larch (Larix decidua Mill.), and two non-native species, black pine (Pinus nigra Arnold) and Douglas fir (Pseudotsuga menziesii Mirb. var. menziesii), to drought. This involved analysing how the radial increment of these species responded to increasing water shortage (abandonment of irrigation) and to increasingly frequent drought years. Black pine and Douglas fir are able to cope with drought better than Scots pine and larch, as they show relatively high radial growth even after irrigation has been stopped and a plastic growth response to drought years. European larch does not seem to be able to cope with these dry conditions as it lacks the ability to recover from drought years. The analysis of trees' short-term response to extreme climate events seems to be the most promising and suitable method for detecting how tolerant a tree species is towards drought. However, combining all the methods used in this study provides a complete picture of how water shortage could limit species.},
  language  = {en}
}
@incollection{Kurz2012,
  author    = {Kurz, Melanie},
  title     = {Prizing \& Pricing : Design zwischen Rang und Regal},
  series = {Vielen Dank f{\"u}r Ihren Einkauf : Konsumkultur aus Sicht von Design, Kunst und Medien},
  booktitle = {Vielen Dank f{\"u}r Ihren Einkauf : Konsumkultur aus Sicht von Design, Kunst und Medien},
  publisher = {Transcript Verlag},
  address   = {Bielefeld},
  isbn      = {978-3-8376-2170-9},
  doi       = {10.1515/transcript.9783839421703.26},
  pages     = {26 -- 39},
  year      = {2012},
  language  = {de}
}
@article{RiglingBiglerEilmannetal.2012,
  author    = {Rigling, Andreas and Bigler, Christof and Eilmann, Britta and Feldmeyer-Christe, Elisabeth and Gimmi, Urs and Ginzler, Christian and Graf, Ulrich and Mayer, Phillip and Vacchiano, Giorgio and Weber, Pascal and Wohlgemuth, Thomas and zweifel, Roman and Dobbertin, Matthias},
  title     = {Driving factors of a vegetation shift from Scots pine to pubescent oak in dry Alpine forests},
  series = {Global Change Biology},
  volume    = {19},
  journal   = {Global Change Biology},
  number    = {1},
  publisher = {Wiley-Blackwell},
  address   = {Oxford},
  issn      = {1354-1013 (Print)},
  doi       = {10.1111/gcb.12038},
  pages     = {229 -- 240},
  year      = {2012},
  abstract  = {An increasing number of studies have reported on forest declines and vegetation shifts triggered by drought. In the Swiss Rhone valley (Valais), one of the driest inner-Alpine regions, the species composition in low elevation forests is changing: The sub-boreal Scots pine (Pinus sylvestris L.) dominating the dry forests is showing high mortality rates. Concurrently the sub-Mediterranean pubescent oak (Quercus pubescens Willd.) has locally increased in abundance. However, it remains unclear whether this local change in species composition is part of a larger-scale vegetation shift. To study variability in mortality and regeneration in these dry forests we analysed data from the Swiss national forest inventory (NFI) on a regular grid between 1983 and 2003, and combined it with annual mortality data from a monitoring site. Pine mortality was found to be highest at low elevation (below 1000 m a.s.l.). Annual variation in pine mortality was correlated with a drought index computed for the summer months prior to observed tree death. A generalized linear mixed-effects model indicated for the NFI data increased pine mortality on dryer sites with high stand competition, particularly for small-diameter trees. Pine regeneration was low in comparison to its occurrence in the overstorey, whereas oak regeneration was comparably abundant. Although both species regenerated well at dry sites, pine regeneration was favoured at cooler sites at higher altitude and oak regeneration was more frequent at warmer sites, indicating a higher adaptation potential of oaks under future warming. Our results thus suggest that an extended shift in species composition is actually occurring in the pine forests in the Valais. The main driving factors are found to be climatic variability, particularly drought, and variability in stand structure and topography. Thus, pine forests at low elevations are developing into oak forests with unknown consequences for these ecosystems and their goods and services.},
  language  = {en}
}
@inproceedings{KoetterDeckerDetzleretal.2012,
  author    = {K{\"o}tter, Jens and Decker, Stefan and Detzler, Raphael and Sch{\"a}fer, Jochen and Schmitz, Mark and Herrmann, Ulf},
  title     = {Cost Reduction of Solar Fields with HelioTrough Collector},
  publisher = {FLAGSOL},
  address   = {K{\"o}ln},
  pages     = {9 S. : Ill., graph. Darst.},
  year      = {2012},
  language  = {en}
}
@incollection{NiendorfWinterFrauenrath2012,
  author    = {Niendorf, Thoralf and Winter, Lukas and Frauenrath, Tobias},
  title     = {Electrocardiogram in an MRI environment: Clinical needs, practical considerations, safety implications, technical solutions and fFuture directions},
  series = {Advances in Electrocardiograms - Methods and Analysis},
  booktitle = {Advances in Electrocardiograms - Methods and Analysis},
  editor    = {Millis, Richard},
  publisher = {IntechOpen},
  address   = {London},
  isbn      = {978-953-307-923-3 (print)},
  doi       = {10.5772/24340},
  pages     = {309 -- 324},
  year      = {2012},
  language  = {en}
}
@article{BragardBragard2012,
  author    = {Bragard, G. and Bragard, Michael},
  title     = {Ein kosteng{\"u}nstiges, universelles Modellbauinterface},
  series = {Der mathematische und naturwissenschaftliche Unterricht : MNU ; Organ des Deutschen Vereins zur F{\"o}rderung des Mathematischen und Naturwissenschaftlichen Unterrichts e.V.},
  volume    = {65},
  journal   = {Der mathematische und naturwissenschaftliche Unterricht : MNU ; Organ des Deutschen Vereins zur F{\"o}rderung des Mathematischen und Naturwissenschaftlichen Unterrichts e.V.},
  number    = {5},
  publisher = {Seeberger},
  address   = {Neuss},
  issn      = {0025-5866},
  pages     = {290 -- 293},
  year      = {2012},
  abstract  = {Wir stellen einen USB-Baustein vor, der eine kosteng{\"u}nstige und universelle M{\"o}glichkeit schafft , im Unterricht den Themenkreis Messen-Steuern-Regeln zu behandeln. Die Funktionalit{\"a}t orientiert sich am CVK-Interface der Firma Fischertechnik. Im Gegensatz zu kommerziellen L{\"o}sungen erlaubt unser Aufbau auch den preiswerten Einsatz in Gruppen- oder Einzelarbeit. Abschließend berichten wir {\"u}ber ein Beispiel aus dem Unterrichtseinsatz.},
  language  = {de}
}