@article{MiyamotoBingWagneretal.2015, author = {Miyamoto, Ko-ichiro and Bing, Yu and Wagner, Torsten and Yoshinobu, Tatsuo and Sch{\"o}ning, Michael Josef}, title = {Visualization of Defects on a Cultured Cell Layer by Utilizing Chemical Imaging Sensor}, series = {Procedia Engineering}, volume = {120}, journal = {Procedia Engineering}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1877-7058}, doi = {10.1016/j.proeng.2015.08.806}, pages = {936 -- 939}, year = {2015}, abstract = {The chemical imaging sensor is a field-effect sensor which is able to visualize both the distribution of ions (in LAPS mode) and the distribution of impedance (in SPIM mode) inthe sample. In this study, a novel wound-healing assay is proposed, in which the chemical imaging sensor operated in SPIM mode is applied to monitor the defect of a cell layer brought into proximity of the sensing surface.A reduced impedance inside the defect, which was artificially formed ina cell layer, was successfully visualized in a photocurrent image.}, language = {en} } @article{MolinnusBaeckerIkenetal.2015, author = {Molinnus, Denise and B{\"a}cker, Matthias and Iken, Heiko and Poghossian, Arshak and Keusgen, Michael and Sch{\"o}ning, Michael Josef}, title = {Concept for a biomolecular logic chip with an integrated sensor and actuator function}, series = {Physica status solidi (a)}, volume = {212}, journal = {Physica status solidi (a)}, number = {6}, publisher = {Wiley}, address = {Weinheim}, issn = {1862-6319}, doi = {10.1002/pssa.201431913}, pages = {1382 -- 1388}, year = {2015}, abstract = {A concept for a new generation of an integrated multi-functional biosensor/actuator system is developed, which is based on biomolecular logic principles. Such a system is expected to be able to detect multiple biochemical input signals simultaneously and in real-time and convert them into electrical output signals with logical operations such as OR, AND, etc. The system can be designed as a closed-loop drug release device triggered by an enzyme logic gate, while the release of the drug induced by the actuator at the required dosage and timing will be controlled by an additional drug sensor. Thus, the system could help to make an accurate and specific diagnosis. The presented concept is exemplarily demonstrated by using an enzyme logic gate based on a glucose/glucose oxidase system, a temperature-responsive hydrogel mimicking the actuator function and an insulin (drug) sensor. In this work, the results of functional testing of individual amperometric glucose and insulin sensors as well as an impedimetric sensor for the detection of the hydrogel swelling/shrinking are presented.}, language = {en} } @article{MolinnusBaeckerSiegertetal.2015, author = {Molinnus, Denise and B{\"a}cker, Matthias and Siegert, Petra and Willenberg, H. and Poghossian, Arshak and Keusgen, M. and Sch{\"o}ning, Michael Josef}, title = {Detection of Adrenaline Based on Substrate Recycling Amplification}, series = {Procedia Engineering}, volume = {120}, journal = {Procedia Engineering}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1877-7058}, doi = {10.1016/j.proeng.2015.08.708}, pages = {540 -- 543}, year = {2015}, abstract = {An amperometric enzyme biosensor has been applied for the detection of adrenaline. The adrenaline biosensor has been prepared by modification of an oxygen electrode with the enzyme laccase that operates at a broad pH range between pH 3.5 to pH 8. The enzyme molecules were immobilized via cross-linking with glutaraldehyde. The sensitivity of the developed adrenaline biosensor in different pH buffer solutions has been studied.}, language = {en} } @article{MulhernBialonskiKantz2015, author = {Mulhern, Colm and Bialonski, Stephan and Kantz, Holger}, title = {Extreme events due to localization of energy}, series = {Physical Review E}, volume = {91}, journal = {Physical Review E}, number = {1}, issn = {2470-0053}, doi = {10.1103/PhysRevE.91.012918}, pages = {012918}, year = {2015}, language = {en} } @article{MuribYeapMartensetal.2015, author = {Murib, M. S. and Yeap, W. S. and Martens, D. and Liu, X. and Bienstman, P. and Fahlman, M. and Sch{\"o}ning, Michael Josef and Michiels, L. and Haenen, K. and Serpeng{\"u}zel, A. and Wagner, Patrick}, title = {Photonic studies on polymer-coated sapphire-spheres : a model system for biological ligands}, series = {Sensors and actuators A: Physical}, volume = {222}, journal = {Sensors and actuators A: Physical}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1873-3069 (E-Journal); 0924-4247 (Print)}, doi = {10.1016/j.sna.2014.11.024}, pages = {212 -- 219}, year = {2015}, abstract = {In this study we show an optical biosensor concept, based on elastic light scattering from sapphire microspheres. Transmitted and elastic scattering intensity of the microspheres (radius 500 μm, refractive index 1.77) on an optical fiber half coupler is analyzed at 1510 nm. The 0.43 nm angular mode spacing of the resonances is comparable to the angular mode spacing value estimated using the optical size of the microsphere. The spectral linewidths of the resonances are in the order of 0.01 nm, which corresponds to quality factors of approximately 105. A polydopamine layer is used as a functionalizing agent on sapphire microspherical resonators in view of biosensor implementation. The varying layer thickness on the microsphere is determined as a function of the resonance wavelength shift. It is shown that polymer functionalization has a minor effect on the quality factor. This is a promising step toward the development of an optical biosensor.}, language = {en} } @inproceedings{NakagawaMichauxKallweitetal.2015, author = {Nakagawa, Masaki and Michaux, Frank and Kallweit, Stephan and Maeda, Kazuhiro}, title = {Unsteady flow measurements in the wake behind a wind-tunnel car model by using high-speed planar PIV}, series = {11TH International Symposium on Particle Image Velocimetry - PIV15 Santa Barbara, California, September 14-16, 2015}, booktitle = {11TH International Symposium on Particle Image Velocimetry - PIV15 Santa Barbara, California, September 14-16, 2015}, pages = {21 S.}, year = {2015}, abstract = {This study investigates unsteady characteristics of the wake behind a 28\%-scale car model in a wind tunnel using highspeed planar particle image velocimetry (PIV). The car model is based on a hatchback passenger car that is known to have relatively high fluctuations in its aerodynamic loads. This study primarily focuses on the lateral motion of the flow on the horizontal plane to determine the effect of the flow motion on the straight-line stability and the initial steering response of the actual car on a track. This paper first compares the flow fields in the wake behind the above mentioned model obtained using conventional and high-speed planar PIV, with sampling frequencies of 8 Hz and 1 kHz, respectively. Large asymmetrically coherent flow structures, which fluctuate at frequencies below 2 Hz, are observed in the results of highspeed PIV measurements, whereas conventional PIV is unable to capture these features of the flow owing to aliasing. This flow pattern with a laterally swaying motion is represented by opposite signs of cross-correlation coefficients of streamwise velocity fluctuations for the two sides of the car model. Effects of two aerodynamic devices that are known to reduce the fluctuation levels of the aerodynamic loads are then extensively investigated. The correlation analyses reveal that these devices indeed reduce the fluctuation levels of the flow and the correlation values around the rear combination-lamp, but it is found that the effects of these devices are different around the c-pillar.}, language = {en} } @inproceedings{NeuJanserKhatibietal.2015, author = {Neu, Eugen and Janser, Frank and Khatibi, Akbar A. and Orifici, Adrian C.}, title = {Operational modal analysis of a cantilever in a wind tunnel using optical fiber bragg grating sensors}, series = {6th International Operational Modal Analysis Conference. IOMAC´15. 2015 May 12-14 Gijon - Spain}, booktitle = {6th International Operational Modal Analysis Conference. IOMAC´15. 2015 May 12-14 Gijon - Spain}, doi = {10.13140/RG.2.1.3753.0324}, pages = {10 S.}, year = {2015}, language = {en} } @inproceedings{NiemuellerFerreinReuteretal.2015, author = {Niemueller, Tim and Ferrein, Alexander and Reuter, Sebastian and Jeschke, Sabina and Lakemeyer, Gerhard}, title = {The RoboCup Logistics League as a Holistic Multi-Robot Smart Factory Benchmark}, series = {Proceedings of the IROS 2015 Open forum on evaluation of results, replication of experiments and benchmarking in robotics research}, booktitle = {Proceedings of the IROS 2015 Open forum on evaluation of results, replication of experiments and benchmarking in robotics research}, pages = {3 S.}, year = {2015}, abstract = {With autonomous mobile robots receiving increased attention in industrial contexts, the need for benchmarks becomes more and more an urgent matter. The RoboCup Logistics League (RCLL) is one specific industry-inspired scenario focusing on production logistics within a Smart Factory. In this paper, we describe how the RCLL allows to assess the performance of a group of robots within the scenario as a whole, focusing specifically on the coordination and cooperation strategies and the methods and components to achieve them. We report on recent efforts to analyze performance of teams in 2014 to understand the implications of the current grading scheme, and derived criteria and metrics for performance assessment based on Key Performance Indicators (KPI) adapted from classic factory evaluation. We reflect on differences and compatibility towards RoCKIn, a recent major benchmarking European project.}, language = {en} } @inproceedings{NiemuellerLakemeyerFerrein2015, author = {Niemueller, Tim and Lakemeyer, Gerhard and Ferrein, Alexander}, title = {The RoboCup Logistics League as a Benchmark for Planning in Robotics}, series = {Proceedings of the 3rd Workshop on Planning and Robotics (PlanRob-15); Jerusalem, Israel 7-8/6/2015}, booktitle = {Proceedings of the 3rd Workshop on Planning and Robotics (PlanRob-15); Jerusalem, Israel 7-8/6/2015}, editor = {Finzi, Alberto}, pages = {63 -- 68}, year = {2015}, language = {en} } @incollection{NiemuellerReuterEwertetal.2015, author = {Niemueller, Tim and Reuter, Sebastian and Ewert, Daniel and Ferrein, Alexander and Jeschke, Sabina and Lakemeyer, Gerhard}, title = {Decisive Factors for the Success of the Carologistics RoboCup Team in the RoboCup Logistics League 2014}, series = {RoboCup 2014: Robot World Cup XVIII}, booktitle = {RoboCup 2014: Robot World Cup XVIII}, publisher = {Springer}, isbn = {978-3-319-18615-3}, pages = {155 -- 167}, year = {2015}, language = {en} }