@inproceedings{SchifferBragard2019,
  author    = {Schiffer, Fabian and Bragard, Michael},
  title     = {Cascaded LQ and Field-Oriented Control of a Mobile Inverse Pendulum (Segway) with Permanent Magnet Synchronous Machines},
  series = {2019 20th International Conference on Research and Education in Mechatronics (REM)},
  booktitle = {2019 20th International Conference on Research and Education in Mechatronics (REM)},
  isbn      = {978-1-5386-9257-8},
  doi       = {10.1109/REM.2019.8744101},
  pages     = {1 -- 8},
  year      = {2019},
  language  = {en}
}
@inproceedings{BragardSubeSchneideretal.2019,
  author    = {Bragard, Michael and Sube, Maike and Schneider, Maike and Jungemann, Christoph},
  title     = {Introducing a Cross-University Bachelor's Programme with Orientation Semester - Enabling a Permeable Academic Education System},
  series = {2019 20th International Conference on Research and Education in Mechatronics (REM)},
  booktitle = {2019 20th International Conference on Research and Education in Mechatronics (REM)},
  isbn      = {978-1-5386-9257-8},
  doi       = {10.1109/REM.2019.8744132},
  pages     = {1 -- 6},
  year      = {2019},
  language  = {en}
}
@article{Stulpe2019,
  author    = {Stulpe, Werner},
  title     = {Aspects of the Quantum-Classical Connection Based on Statistical Maps},
  series = {Foundations of Physics},
  volume    = {49},
  journal   = {Foundations of Physics},
  number    = {6},
  publisher = {Springer},
  address   = {Berlin},
  doi       = {10.1007/s10701-019-00269-9},
  pages     = {677 -- 692},
  year      = {2019},
  language  = {en}
}
@article{WeberEnglhardArentetal.2019,
  author    = {Weber, Tobias and Englhard, Markus and Arent, Jan-Christoph and Hausmann, Joachim},
  title     = {An experimental characterization of wrinkling generated during prepreg autoclave manufacturing using caul plates},
  series = {Journal of Composite Materials},
  volume    = {53},
  journal   = {Journal of Composite Materials},
  number    = {26-27},
  issn      = {1530-793X},
  doi       = {10.1177/0021998319846556},
  pages     = {3757 -- 3773},
  year      = {2019},
  language  = {en}
}
@inproceedings{HailerWeberArent2019,
  author    = {Hailer, Benjamin and Weber, Tobias and Arent, Jan-Christoph},
  title     = {Manufacturing Process Simulation for Autoclave-Produced Sandwich Structures},
  series = {Proceedings of SAMPE Europe Conference 2019, Nantes, France},
  booktitle = {Proceedings of SAMPE Europe Conference 2019, Nantes, France},
  pages     = {1 -- 8},
  year      = {2019},
  language  = {en}
}
@inproceedings{WeberEnglhardHaileretal.2019,
  author    = {Weber, Tobias and Englhard, Markus and Hailer, Benjamin and Arent, Jan-Christoph},
  title     = {Manufacturing Process Simulation for the Prediction of Tool-Part-Interaction and Ply Wrinkling},
  series = {Proceedings of SAMPE Europe Conference 2019, Nantes, France},
  booktitle = {Proceedings of SAMPE Europe Conference 2019, Nantes, France},
  pages     = {1 -- 10},
  year      = {2019},
  language  = {en}
}
@article{SchiedermeierRettnerHeilmannetal.2019,
  author    = {Schiedermeier, Maximilian and Rettner, Cornelius and Heilmann, Marcel and Schneider, Felix and Marz, Martin},
  title     = {Interference of automotive HV-DC-systems by traction voltage-source-inverters (VSI)},
  series = {2019 IEEE Transportation Electrification Conference (ITEC-India)},
  journal   = {2019 IEEE Transportation Electrification Conference (ITEC-India)},
  publisher = {IEEE},
  address   = {New York},
  doi       = {10.1109/ITEC-India48457.2019.ITECINDIA2019-37},
  pages     = {1 -- 6},
  year      = {2019},
  language  = {en}
}
@article{KunkelGebhardtMpofuetal.2019,
  author    = {Kunkel, Maximilian Hugo and Gebhardt, Andreas and Mpofu, Khumbulani and Kallweit, Stephan},
  title     = {Quality assurance in metal powder bed fusion via deep-learning-based image classification},
  series = {Rapid Prototyping Journal},
  volume    = {26},
  journal   = {Rapid Prototyping Journal},
  number    = {2},
  issn      = {1355-2546},
  doi       = {10.1108/RPJ-03-2019-0066},
  pages     = {259 -- 266},
  year      = {2019},
  language  = {en}
}
@incollection{LeiseAltherrSimonetal.2019,
  author    = {Leise, Philipp and Altherr, Lena and Simon, Nicolai and Pelz, Peter F.},
  title     = {Finding global-optimal gearbox designs for battery electric vehicles},
  series = {Optimization of complex systems - theory, models, algorithms and applications : WCGO 2019},
  booktitle = {Optimization of complex systems - theory, models, algorithms and applications : WCGO 2019},
  publisher = {Springer},
  address   = {Cham},
  isbn      = {978-3-030-21802-7},
  doi       = {10.1007/978-3-030-21803-4_91},
  pages     = {916 -- 925},
  year      = {2019},
  abstract  = {In order to maximize the possible travel distance of battery electric vehicles with one battery charge, it is mandatory to adjust all components of the powertrain carefully to each other. While current vehicle designs mostly simplify the powertrain rigorously and use an electric motor in combination with a gearbox with only one fixed transmission ratio, the use of multi-gear systems has great potential. First, a multi-speed system is able to improve the overall energy efficiency. Secondly, it is able to reduce the maximum momentum and therefore to reduce the maximum current provided by the traction battery, which results in a longer battery lifetime. In this paper, we present a systematic way to generate multi-gear gearbox designs that—combined with a certain electric motor—lead to the most efficient fulfillment of predefined load scenarios and are at the same time robust to uncertainties in the load. Therefore, we model the electric motor and the gearbox within a Mixed-Integer Nonlinear Program, and optimize the efficiency of the mechanical parts of the powertrain. By combining this mathematical optimization program with an unsupervised machine learning algorithm, we are able to derive global-optimal gearbox designs for practically relevant momentum and speed requirements.},
  language  = {en}
}
@incollection{StengerAltherrAbel2019,
  author    = {Stenger, David and Altherr, Lena and Abel, Dirk},
  title     = {Machine learning and metaheuristics for black-box optimization of product families: a case-study investigating solution quality vs. computational overhead},
  series = {Operations Research Proceedings 2018},
  booktitle = {Operations Research Proceedings 2018},
  publisher = {Springer},
  address   = {Cham},
  isbn      = {978-3-030-18499-5 (Print)},
  doi       = {10.1007/978-3-030-18500-8_47},
  pages     = {379 -- 385},
  year      = {2019},
  abstract  = {In product development, numerous design decisions have to be made. Multi-domain virtual prototyping provides a variety of tools to assess technical feasibility of design options, however often requires substantial computational effort for just a single evaluation. A special challenge is therefore the optimal design of product families, which consist of a group of products derived from a common platform. Finding an optimal platform configuration (stating what is shared and what is individually designed for each product) and an optimal design of all products simultaneously leads to a mixed-integer nonlinear black-box optimization model. We present an optimization approach based on metamodels and a metaheuristic. To increase computational efficiency and solution quality, we compare different types of Gaussian process regression metamodels adapted from the domain of machine learning, and combine them with a genetic algorithm. We illustrate our approach on the example of a product family of electrical drives, and investigate the trade-off between solution quality and computational overhead.},
  language  = {en}
}
@inproceedings{GrundmannBauerBodenetal.2019,
  author    = {Grundmann, Jan Thimo and Bauer, Waldemar and Boden, Ralf and Ceriotti, Matteo and Chand, Suditi and Cordero, Federico and Dachwald, Bernd and Dumont, Etienne and Grimm, Christian D. and Heiligers, Jeannette and Herč{\´i}k, David and H{\´e}rique, Alain and Ho, Tra-Mi and Jahnke, Rico and Kofman, Wlodek and Lange, Caroline and Lichtenheldt, Roy and McInnes, Colin and Meß, Jan-Gerd and Mikschl, Tobias and Mikulz, Eugen and Montenegro, Sergio and Moore, Iain and Pelivan, Ivanka and Peloni, Alessandro and Plettemeier, Dirk and Quantius, Dominik and Reershemius, Siebo and Renger, Thomas and Riemann, Johannes and Rogez, Yves and Ruffer, Michael and Sasaki, Kaname and Schmitz, Nicole and Seboldt, Wolfgang and Seefeldt, Patric and Spietz, Peter and Spr{\"o}witz, Tom and Sznajder, Maciej and T{\´o}th, Norbert and Vergaaij, Merel and Viavattene, Giulia and Wejmo, Elisabet and Wiedemann, Carsten and Wolff, Friederike and Ziach, Christian},
  title     = {Flights are ten a sail - Re-use and commonality in the design and system engineering of small spacecraft solar sail missions with modular hardware for responsive and adaptive exploration},
  series = {70th International Astronautical Congress (IAC)},
  booktitle = {70th International Astronautical Congress (IAC)},
  isbn      = {9781713814856},
  pages     = {1 -- 7},
  year      = {2019},
  language  = {en}
}
@book{GebhardtKesslerThurn2019,
  author    = {Gebhardt, Andreas and Kessler, Julia and Thurn, Laura},
  title     = {3D printing : understanding additive manufacturing},
  edition   = {2. Auflage},
  publisher = {Hanser},
  address   = {M{\"u}nchen},
  isbn      = {978-1-56990-702-3},
  pages     = {XVI, 204 Seiten},
  year      = {2019},
  language  = {en}
}
@article{RuppHandschuhRiekeetal.2019,
  author    = {Rupp, Matthias and Handschuh, Nils and Rieke, Christian and Kuperjans, Isabel},
  title     = {Contribution of country-specific electricity mix and charging time to environmental impact of battery electric vehicles: A case study of electric buses in Germany},
  series = {Applied Energy},
  volume    = {237},
  journal   = {Applied Energy},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0306-2619},
  doi       = {10.1016/j.apenergy.2019.01.059},
  pages     = {618 -- 634},
  year      = {2019},
  language  = {en}
}
@article{KramerValeroChansonetal.2019,
  author    = {Kramer, Matthias and Valero, Daniel and Chanson, Hubert and Bung, Daniel Bernhard},
  title     = {Towards reliable turbulence estimations with phase-detection probes: an adaptive window cross-correlation technique},
  series = {Experiments in Fluids},
  volume    = {60},
  journal   = {Experiments in Fluids},
  publisher = {Springer},
  address   = {Berlin},
  issn      = {1432-1114},
  doi       = {10.1007/s00348-018-2650-9},
  year      = {2019},
  language  = {en}
}
@phdthesis{Beckmann2019,
  author    = {Beckmann, Nils},
  title     = {Characterization of the hydrogen-dry-low-Nox-micromix-combustion-principle for hydrogen-methane fuel mixtures},
  publisher = {RMIT University},
  address   = {Melbourne},
  pages     = {XV, 160 Seiten},
  year      = {2019},
  language  = {en}
}
@article{GoettscheAlexopoulosDuemmleretal.2019,
  author    = {G{\"o}ttsche, Joachim and Alexopoulos, Spiros and D{\"u}mmler, Andreas and Maddineni, S. K.},
  title     = {Multi-Mirror Array Calculations With Optical Error},
  pages     = {1 -- 6},
  year      = {2019},
  abstract  = {The optical performance of a 2-axis solar concentrator was simulated with the COMSOL Multiphysics® software. The concentrator consists of a mirror array, which was created using the application builder. The mirror facets are preconfigured to form a focal point. During tracking all mirrors are moved simultaneously in a coupled mode by 2 motors in two axes, in order to keep the system in focus with the moving sun. Optical errors on each reflecting surface were implemented in combination with the solar angular cone of ± 4.65 mrad. As a result, the intercept factor of solar radiation that is available to the receiver was calculated as a function of the transversal and longitudinal angles of incidence. In addition, the intensity distribution on the receiver plane was calculated as a function of the incidence angles.},
  language  = {en}
}
@inproceedings{GrundmannBauerBodenetal.2019,
  author    = {Grundmann, Jan Thimo and Bauer, Waldemar and Boden, Ralf Christian and Ceriotti, Matteo and Cordero, Federico and Dachwald, Bernd and Dumont, Etienne and Grimm, Christian D. and Hercik, D. and Herique, A. and Ho, Tra-Mi and Jahnke, Rico and Kofman, Wlodek and Lange, Caroline and Lichtenheldt, Roy and McInnes, Colin R. and Mikschl, Tobias and Montenegro, Sergio and Moore, Iain and Pelivan, Ivanka and Peloni, Alessandro and Plettenmeier, Dirk and Quantius, Dominik and Reershemius, Siebo and Renger, Thomas and Riemann, Johannes and Rogez, Yves and Ruffer, Michael and Sasaki, Kaname and Schmitz, Nicole and Seboldt, Wolfgang and Seefeldt, Patric and Spietz, Peter and Spr{\"o}witz, Tom and Sznajder, Maciej and Toth, Norbert and Viavattene, Giulia and Wejmo, Elisabet and Wolff, Friederike and Ziach, Christian},
  title     = {Responsive exploration and asteroid characterization through integrated solar sail and lander development using small spacecraft technologies},
  series = {IAA Planetary Defense Conference},
  booktitle = {IAA Planetary Defense Conference},
  year      = {2019},
  abstract  = {In parallel to the evolution of the Planetary Defense Conference, the exploration of small solar system bodies has advanced from fast fly-bys on the sidelines of missions to the planets to the implementation of dedicated sample-return and in-situ analysis missions. Spacecraft of all sizes have landed, touch-and-go sampled, been gently beached, or impacted at hypervelocity on asteroid and comet surfaces. More have flown by close enough to image their surfaces in detail or sample their immediate environment, often as part of an extended or re-purposed mission. And finally, full-scale planetary defense experiment missions are in the making. Highly efficient low-thrust propulsion is increasingly applied beyond commercial use also in mainstream and flagship science missions, in combination with gravity assist propulsion. Another development in the same years is the growth of small spacecraft solutions, not in size but in numbers and individual capabilities. The on-going NASA OSIRIS-REx and JAXA HAYABUSA2 missions exemplify the trend as well as the upcoming NEA SCOUT mission or the landers MINERVA-II and MASCOT recently deployed on Ryugu. We outline likely as well as possible and efficient routes of continuation of all these developments towards a propellant-less and highly efficient class of spacecraft for small solar system body exploration: small spacecraft solar sails designed for carefree handling and equipped with carried landers and application modules, for all asteroid user communities -planetary science, planetary defence, and in-situ resource utilization. This projection builds on the experience gained in the development of deployable membrane structures leading up to the successful ground deployment test of a (20 m)² solar sail at DLR Cologne and in the 20 years since. It draws on the background of extensive trajectory optimization studies, the qualified technology of the DLR GOSSAMER-1 deployment demonstrator, and the MASCOT asteroid lander. These enable 'now-term' as well as near-term hardware solutions, and thus responsive fast-paced development. Mission types directly applicable to planetary defense include: single and Multiple NEA Rendezvous ((M)NR) for mitigation precursor, target monitoring and deflection follow-up tasks; sail-propelled head-on retrograde kinetic impactors (RKI) for mitigation; and deployable membrane based methods to modify the asteroid's properties or interact with it. The DLR-ESTEC GOSSAMER Roadmap initiated studies of missions uniquely feasible with solar sails such as Displaced L1 (DL1) space weather advance warning and monitoring and Solar Polar Orbiter (SPO) delivery which demonstrate the capability of near-term solar sails to achieve NEA rendezvous in any kind of orbit, from Earth-coorbital to extremely inclined and even retrograde orbits. For those mission types using separable payloads, such as SPO, (M)NR and RKI, design concepts can be derived from the separable Boom Sail Deployment Units characteristic of DLR GOSSAMER solar sail technology, nanolanders like MASCOT, or microlanders like the JAXA-DLR Jupiter Trojan Asteroid Lander for the OKEANOS mission which can shuttle from the sail to the asteroids visited and enable multiple NEA sample-return missions. These are an ideal match for solar sails in micro-spacecraft format whose launch configurations are compatible with ESPA and ASAP secondary payload platforms.},
  language  = {en}
}
@inproceedings{GrundmannBauerBodenetal.2019,
  author    = {Grundmann, Jan Thimo and Bauer, Waldemar and Boden, Ralf Christian and Ceriotti, Matteo and Cordero, Federico and Dachwald, Bernd and Dumont, Etienne and Grimm, Christian D. and Hercik, D. and Herique, A. and Ho, Tra-Mi and Jahnke, Rico and Kofman, Wlodek and Lange, Caroline and Lichtenheldt, Roy and McInnes, Colin R. and Mikschl, Tobias and Mikulz, Eugen and Montenegro, Sergio and Moore, Iain and Pelivan, Ivanka and Peloni, Alessandro and Plettemeier, Dirk and Quantius, Dominik and Reershemius, Siebo and Renger, Thomas and Riemann, Johannes and Rogez, Yves and Ruffer, Michael and Sasaki, Kaname and Schmitz, Nicole and Seboldt, Wolfgang and Seefeldt, Patric and Spietz, Peter and Spr{\"o}witz, Tom and Sznajder, Maciej and Toth, Norbert and Viavattene, Giulia and Wejmo, Elisabet and Wolff, Friederike and Ziach, Christian},
  title     = {Responsive integrated small spacecraft solar sail and payload design concepts and missions},
  series = {Conference: 5th International Symposium on Solar Sailing (ISSS 2019)},
  booktitle = {Conference: 5th International Symposium on Solar Sailing (ISSS 2019)},
  year      = {2019},
  abstract  = {Asteroid mining has the potential to greatly reduce the cost of in-space manufacturing, production of propellant for space transportation and consumables for crewed spacecraft, compared to launching the required resources from Earth's deep gravity well. This paper discusses the top-level mission architecture and trajectory design for these resource-return missions, comparing high-thrust trajectories with continuous low-thrust solar-sail trajectories. This work focuses on maximizing the economic Net Present Value, which takes the time-cost of finance into account and therefore balances the returned resource mass and mission duration. The different propulsion methods will then be compared in terms of maximum economic return, sets of attainable target asteroids, and mission flexibility. This paper provides one more step towards making commercial asteroid mining an economically viable reality by integrating trajectory design, propulsion technology and economic modelling.},
  language  = {en}
}
@inproceedings{MarinkovićButenweg2019,
  author    = {Marinković, Marko and Butenweg, Christoph},
  title     = {Experimental and numerical analysis of RC frames with decoupled masonry infills},
  series = {7th ECCOMAS Thematic Conference on Computational Methods in Structural Dynamics and Earthquake Engineering},
  booktitle = {7th ECCOMAS Thematic Conference on Computational Methods in Structural Dynamics and Earthquake Engineering},
  editor    = {Papadrakakis, Manolis and Fragiadakis, Michalis},
  publisher = {National Technical University of Athens},
  address   = {Athen},
  isbn      = {978-618-82844-5-6},
  issn      = {2623-3347},
  doi       = {10.7712/120119.7088.18845},
  pages     = {2464 -- 2479},
  year      = {2019},
  abstract  = {Masonry infill walls are commonly used in reinforced concrete (RC) frame structures, also in seismically active areas, although they often experience serious damage during earthquakes. One of the main reasons for their poor behaviour is the connection to the frame, which is usually constructed using mortar. This paper describes the novel solution for infill/frame connection based on application of elastomeric material between them. The system called INODIS (Innovative Decoupled Infill System) has the aim to postpone the activation of infill in in-plane direction and at the same time to provide sufficient out-of-plane support. First, experimental tests on infilled frame specimens are presented and the comparison of the results between traditionally infilled frames and infilled frames with the INODIS system are given. The results are then used for calibration and validation of numerical model, which can be further employed for investigating the influence of some material parameters on the behaviour of infilled frames with the INODIS system.},
  language  = {en}
}
@article{BaringhausGaigall2019,
  author    = {Baringhaus, Ludwig and Gaigall, Daniel},
  title     = {On an asymptotic relative efficiency concept based on expected volumes of confidence regions},
  series = {Statistics - A Journal of Theoretical and Applied Statistic},
  volume    = {53},
  journal   = {Statistics - A Journal of Theoretical and Applied Statistic},
  number    = {6},
  publisher = {Taylor \& Francis},
  address   = {London},
  issn      = {1029-4910},
  doi       = {10.1080/02331888.2019.1683560},
  pages     = {1396 -- 1436},
  year      = {2019},
  abstract  = {The paper deals with an asymptotic relative efficiency concept for confidence regions of multidimensional parameters that is based on the expected volumes of the confidence regions. Under standard conditions the asymptotic relative efficiencies of confidence regions are seen to be certain powers of the ratio of the limits of the expected volumes. These limits are explicitly derived for confidence regions associated with certain plugin estimators, likelihood ratio tests and Wald tests. Under regularity conditions, the asymptotic relative efficiency of each of these procedures with respect to each one of its competitors is equal to 1. The results are applied to multivariate normal distributions and multinomial distributions in a fairly general setting.},
  language  = {en}
}
@article{Gaigall2019,
  author    = {Gaigall, Daniel},
  title     = {On a new approach to the multi-sample goodness-of-fit problem},
  series = {Communications in Statistics - Simulation and Computation},
  volume    = {53},
  journal   = {Communications in Statistics - Simulation and Computation},
  number    = {10},
  publisher = {Taylor \& Francis},
  address   = {London},
  issn      = {1532-4141},
  doi       = {10.1080/03610918.2019.1618472},
  pages     = {2971 -- 2989},
  year      = {2019},
  abstract  = {Suppose we have k samples X₁,₁,…,X₁,ₙ₁,…,Xₖ,₁,…,Xₖ,ₙₖ with different sample sizes ₙ₁,…,ₙₖ and unknown underlying distribution functions F₁,…,Fₖ as observations plus k families of distribution functions {G₁(⋅,ϑ);ϑ∈Θ},…,{Gₖ(⋅,ϑ);ϑ∈Θ}, each indexed by elements ϑ from the same parameter set Θ, we consider the new goodness-of-fit problem whether or not (F₁,…,Fₖ) belongs to the parametric family {(G₁(⋅,ϑ),…,Gₖ(⋅,ϑ));ϑ∈Θ}. New test statistics are presented and a parametric bootstrap procedure for the approximation of the unknown null distributions is discussed. Under regularity assumptions, it is proved that the approximation works asymptotically, and the limiting distributions of the test statistics in the null hypothesis case are determined. Simulation studies investigate the quality of the new approach for small and moderate sample sizes. Applications to real-data sets illustrate how the idea can be used for verifying model assumptions.},
  language  = {en}
}
@article{AchtsnichtNeuendorfFassbenderetal.2019,
  author    = {Achtsnicht, Stefan and Neuendorf, Christian and Faßbender, Tobias and N{\"o}lke, Greta and Offenh{\"a}usser, Andreas and Krause, Hans-Joachim and Schr{\"o}per, Florian},
  title     = {Sensitive and rapid detection of cholera toxin subunit B using magnetic frequency mixing detection},
  series = {Plos One},
  volume    = {14},
  journal   = {Plos One},
  number    = {7},
  publisher = {Plos},
  address   = {San Francisco},
  issn      = {1932-6203},
  doi       = {10.1371/journal.pone.0219356},
  pages     = {e0219356},
  year      = {2019},
  abstract  = {Cholera is a life-threatening disease caused by the cholera toxin (CT) as produced by some Vibrio cholerae serogroups. In this research we present a method which directly detects the toxin's B subunit (CTB) in drinking water. For this purpose we performed a magnetic sandwich immunoassay inside a 3D immunofiltration column. We used two different commercially available antibodies to capture CTB and for binding to superparamagnetic beads. ELISA experiments were performed to select the antibody combination. The beads act as labels for the magnetic frequency mixing detection technique. We show that the limit of detection depends on the type of magnetic beads. A nonlinear Hill curve was fitted to the calibration measurements by means of a custom-written python software. We achieved a sensitive and rapid detection of CTB within a broad concentration range from 0.2 ng/ml to more than 700 ng/ml.},
  language  = {en}
}
@article{AchtsnichtPourshahidiOffenhaeusseretal.2019,
  author    = {Achtsnicht, Stefan and Pourshahidi, Ali Mohammad and Offenh{\"a}usser, Andreas and Krause, Hans-Joachim},
  title     = {Multiplex detection of different magnetic beads using frequency scanning in magnetic frequency mixing technique},
  series = {Sensors},
  volume    = {19},
  journal   = {Sensors},
  number    = {11},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {1424-8220},
  doi       = {10.3390/s19112599},
  pages     = {13 Seiten},
  year      = {2019},
  abstract  = {In modern bioanalytical methods, it is often desired to detect several targets in one sample within one measurement. Immunological methods including those that use superparamagnetic beads are an important group of techniques for these applications. The goal of this work is to investigate the feasibility of simultaneously detecting different superparamagnetic beads acting as markers using the magnetic frequency mixing technique. The frequency of the magnetic excitation field is scanned while the lower driving frequency is kept constant. Due to the particles' nonlinear magnetization, mixing frequencies are generated. To record their amplitude and phase information, a direct digitization of the pickup-coil's signal with subsequent Fast Fourier Transformation is performed. By synchronizing both magnetic beads using frequency scanning in magnetic frequency mixing technique magnetic fields, a stable phase information is gained. In this research, it is shown that the amplitude of the dominant mixing component is proportional to the amount of superparamagnetic beads inside a sample. Additionally, it is shown that the phase does not show this behaviour. Excitation frequency scans of different bead types were performed, showing different phases, without correlation to their diverse amplitudes. Two commercially available beads were selected and a determination of their amount in a mixture is performed as a demonstration for multiplex measurements.},
  language  = {en}
}
@article{AchtsnichtToedterNiehuesetal.2019,
  author    = {Achtsnicht, Stefan and T{\"o}dter, Julia and Niehues, Julia and Tel{\"o}ken, Matthias and Offenh{\"a}usser, Andreas and Krause, Hans-Joachim and Schr{\"o}per, Florian},
  title     = {3D printed modular immunofiltration columns for frequency mixing-based multiplex magnetic immunodetection},
  series = {Sensors},
  volume    = {19},
  journal   = {Sensors},
  number    = {1},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {1424-8220},
  doi       = {10.3390/s19010148},
  pages     = {15 Seiten},
  year      = {2019},
  abstract  = {For performing point-of-care molecular diagnostics, magnetic immunoassays constitute a promising alternative to established enzyme-linked immunosorbent assays (ELISA) because they are fast, robust and sensitive. Simultaneous detection of multiple biomolecular targets from one body fluid sample is desired. The aim of this work is to show that multiplex magnetic immunodetection based on magnetic frequency mixing by means of modular immunofiltration columns prepared for different targets is feasible. By calculations of the magnetic response signal, the required spacing between the modules was determined. Immunofiltration columns were manufactured by 3D printing and antibody immobilization was performed in a batch approach. It was shown experimentally that two different target molecules in a sample solution could be individually detected in a single assaying step with magnetic measurements of the corresponding immobilization filters. The arrangement order of the filters and of a negative control did not influence the results. Thus, a simple and reliable approach to multi-target magnetic immunodetection was demonstrated.},
  language  = {en}
}
@article{AchtsnichtSchoenenbornOffenhaeusseretal.2019,
  author    = {Achtsnicht, Stefan and Sch{\"o}nenborn, Kristina and Offenh{\"a}usser, Andreas and Krause, Hans-Joachim},
  title     = {Measurement of the magnetophoretic velocity of different superparamagnetic beads},
  series = {Journal of Magnetism and Magnetic Materials},
  volume    = {477},
  journal   = {Journal of Magnetism and Magnetic Materials},
  number    = {1},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0304-8853},
  doi       = {10.1016/j.jmmm.2018.10.066},
  pages     = {244 -- 248},
  year      = {2019},
  abstract  = {The movement of magnetic beads due to a magnetic field gradient is of great interest in different application fields. In this report we present a technique based on a magnetic tweezers setup to measure the velocity factor of magnetically actuated individual superparamagnetic beads in a fluidic environment. Several beads can be tracked simultaneously in order to gain and improve statistics. Furthermore we show our results for different beads with hydrodynamic diameters between 200 and 1000 nm from diverse manufacturers. These measurement data can, for example, be used to determine design parameters for a magnetic separation system, like maximum flow rate and minimum separation time, or to select suitable beads for fixed experimental requirements.},
  language  = {en}
}
@article{KetelhutKolditzGoelletal.2019,
  author    = {Ketelhut, Maike and Kolditz, Melanie and G{\"o}ll, Fabian and Braunstein, Bjoern and Albracht, Kirsten and Abel, Dirk},
  title     = {Admittance control of an industrial robot during resistance training},
  series = {IFAC-PapersOnLine},
  volume    = {52},
  journal   = {IFAC-PapersOnLine},
  number    = {19},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {2405-8963},
  doi       = {10.1016/j.ifacol.2019.12.102},
  pages     = {223 -- 228},
  year      = {2019},
  abstract  = {Neuromuscular strength training of the leg extensor muscles plays an important role in the rehabilitation and prevention of age and wealth related diseases. In this paper, we focus on the design and implementation of a Cartesian admittance control scheme for isotonic training, i.e. leg extension and flexion against a predefined weight. For preliminary testing and validation of the designed algorithm an experimental research and development platform consisting of an industrial robot and a force plate mounted at its end-effector has been used. Linear, diagonal and arbitrary two-dimensional motion trajectories with different weights for the leg extension and flexion part are applied. The proposed algorithm is easily adaptable to trajectories consisting of arbitrary six-dimensional poses and allows the implementation of individualized trajectories.},
  language  = {en}
}
@inproceedings{KetelhutGoellBraunsteinetal.2019,
  author    = {Ketelhut, Maike and G{\"o}ll, Fabian and Braunstein, Bjoern and Albracht, Kirsten and Abel, Dirk},
  title     = {Iterative learning control of an industrial robot for neuromuscular training},
  series = {2019 IEEE Conference on Control Technology and Applications},
  booktitle = {2019 IEEE Conference on Control Technology and Applications},
  publisher = {IEEE},
  address   = {New York},
  isbn      = {978-1-7281-2767-5 (ePub)},
  doi       = {10.1109/CCTA.2019.8920659},
  pages     = {7 Seiten},
  year      = {2019},
  abstract  = {Effective training requires high muscle forces potentially leading to training-induced injuries. Thus, continuous monitoring and controlling of the loadings applied to the musculoskeletal system along the motion trajectory is required. In this paper, a norm-optimal iterative learning control algorithm for the robot-assisted training is developed. The algorithm aims at minimizing the external knee joint moment, which is commonly used to quantify the loading of the medial compartment. To estimate the external knee joint moment, a musculoskeletal lower extremity model is implemented in OpenSim and coupled with a model of an industrial robot and a force plate mounted at its end-effector. The algorithm is tested in simulation for patients with varus, normal and valgus alignment of the knee. The results show that the algorithm is able to minimize the external knee joint moment in all three cases and converges after less than seven iterations.},
  language  = {en}
}
@misc{BlottnerHastermannMuckeltetal.2019,
  author    = {Blottner, Dieter and Hastermann, Maria and Muckelt, Paul and Albracht, Kirsten and Schoenrock, Britt and Salanova, Michele and Warner, Martin and Gunga, Hans-Christian and Stokes, Maria},
  title     = {MYOTONES - Inflight muscle health status monitoring during long-duration space missions onboard the International Space Station: a single case study},
  series = {IAC Papers Archive},
  journal   = {IAC Papers Archive},
  publisher = {Pergamon},
  address   = {Oxford},
  issn      = {00741795},
  pages     = {2 Seiten},
  year      = {2019},
  abstract  = {The MYOTONES experiment is the first to monitor changes in the basic biomechanical properties (tone, elasticity and stiffness) of the resting human myofascial system due to microgravity with a oninvasive, portable device on board the ISS. The MyotonPRO device applies several brief mechanical stimuli to the surface of the skin, and the natural oscillation signals of the tissue beneath are detected and computed by the MyotonPRO. Thus, an objective, quick and easy determination of the state of the underlying tissue is possible. Two preflight, four inflight and four post flight measurements were performed on a male astronaut using the same 10 measurement points (MP) for each session. MPs were located on the plantar fascia, Achilles tendon, M. soleus, M. gastrocnemius, M. multifidus, M. splenius capitis, M. deltoideus anterior, M. rectus femoris, infrapatellar tendon, M. tibialis anterior. Subcutaneous tissues thickness above the MPs was measured using ultrasound imaging. Magnetic resonance images (MRI) of lower limb muscles and functional tests were also performed pre- and postflight. Our first measurements on board the ISS confirmed increased tone and stiffness of the lumbar multifidus muscle, an important trunk stabilizer, dysfunction of which is known to be associated with back pain. Furthermore, reduced tone and stiffness of Achilles tendon and plantar fascia were observed inflight vs. preflight, confirming previous findings from terrestrial analog studies and parabolic flights. Unexpectedly, the deltoid showed negative inflight changes in tone and stiffness, and increased elasticity, suggesting a potential risk of muscle atrophy in longer spaceflight that should be addressed by adequate inflight countermeasure protocols. Most values from limb and back MPS showed deflected patterns (in either directions) from inflight shortly after the re-entry phase on the landing day and one week later. Most parameter values then normalized to baseline after 3 weeks likely due to 1G re-adaptation and possible outcome of the reconditioning protocol. No major changes in subcutaneous tissues thickness above the MPs were found inflight vs preflight, suggesting no bias (i.e., fluid shift, extreme tissue thickening or loss). Pre- and postflight MRI and functional tests showed negligible changes in calf muscle size, power and force, which is likely due to training effects from current inflight exercise protocols. The MYOTONES experiment is currently ongoing to collect data from further crew members. The potential impact of this research is to better understand the effects of microgravity and countermeasures over the time course of an ISS mission cycle. This will enable exercise countermeasures to be tailored},
  language  = {en}
}
@article{WerkhausenCroninAlbrachtetal.2019,
  author    = {Werkhausen, Amelie and Cronin, Neil J. and Albracht, Kirsten and Paulsen, G{\o}ran and Larsen, Askild V. and Bojsen-M{\o}ller, Jens and Seynnes, Olivier R.},
  title     = {Training-induced increase in Achilles tendon stiffness affects tendon strain pattern during running},
  series = {PeerJ},
  journal   = {PeerJ},
  publisher = {Peer},
  address   = {London},
  issn      = {21678359},
  doi       = {10.7717/peerj.6764},
  pages     = {18 Seiten},
  year      = {2019},
  abstract  = {Background During the stance phase of running, the elasticity of the Achilles tendon enables the utilisation of elastic energy and allows beneficial contractile conditions for the triceps surae muscles. However, the effect of changes in tendon mechanical properties induced by chronic loading is still poorly understood. We tested the hypothesis that a training-induced increase in Achilles tendon stiffness would result in reduced tendon strain during the stance phase of running, which would reduce fascicle strains in the triceps surae muscles, particularly in the mono-articular soleus. Methods Eleven subjects were assigned to a training group performing isometric singleleg plantarflexion contractions three times per week for ten weeks, and another ten subjects formed a control group. Before and after the training period, Achilles tendon stiffness was estimated, and muscle-tendon mechanics were assessed during running at preferred speed using ultrasonography, kinematics and kinetics. Results Achilles tendon stiffness increased by 18\% (P <0:01) in the training group, but the associated reduction in strain seen during isometric contractions was not statistically significant. Tendon elongation during the stance phase of running was similar after training, but tendon recoil was reduced by 30\% (P <0:01), while estimated tendon force remained unchanged. Neither gastrocnemius medialis nor soleus fascicle shortening during stance was affected by training. Discussion These results show that a training-induced increase in Achilles tendon stiffness altered tendon behaviour during running. Despite training-induced changes in tendon mechanical properties and recoil behaviour, the data suggest that fascicle shortening patterns were preserved for the running speed that we examined. The asymmetrical changes in tendon strain patterns supports the notion that simple inseries models do not fully explain the mechanical output of the muscle-tendon unit during a complex task like running.},
  language  = {en}
}
@incollection{PieronekKleefeld2019,
  author    = {Pieronek, Lukas and Kleefeld, Andreas},
  title     = {The Method of Fundamental Solutions for Computing Interior Transmission Eigenvalues of Inhomogeneous Media},
  series = {Integral Methods in Science and Engineering: Analytic Treatment and Numerical Approximations},
  booktitle = {Integral Methods in Science and Engineering: Analytic Treatment and Numerical Approximations},
  editor    = {Constanda, Christian and Harris, Paul},
  publisher = {Birkh{\"a}user},
  address   = {Cham},
  isbn      = {978-3-030-16077-7},
  doi       = {10.1007/978-3-030-16077-7_28},
  pages     = {353 -- 365},
  year      = {2019},
  abstract  = {The method of fundamental solutions is applied to the approximate computation of interior transmission eigenvalues for a special class of inhomogeneous media in two dimensions. We give a short approximation analysis accompanied with numerical results that clearly prove practical convenience of our alternative approach.},
  language  = {en}
}
@inproceedings{BergmannGraebenerWildetal.2019,
  author    = {Bergmann, Kevin and Gr{\"a}bener, Josefine and Wild, Dominik and Ulfers, H. and Czupalla, Markus},
  title     = {Study on thermal stabilization of a GEO-stationary telescope baffling system by integral application of phase change material},
  series = {International Conference on Environmental Systems},
  booktitle = {International Conference on Environmental Systems},
  pages     = {1 -- 14},
  year      = {2019},
  abstract  = {The utilization of phase change material (PCM) for latent heat storage and thermal control of spacecraft has been demonstrated in the past in few missions only. One limiting factor was the fact that all concepts developed so far envisioned the PCM to be applied as an additional capacitor, encapsulated in its own housing, leading to mass, efficiency and accommodation challenges. Recently, the application of PCM within the scan cavity of a GEOS type satellite has been suggested, in order to tackle thermal issues due to direct sun intrusion (Choi, M., 2014). However, the application of PCM in such complex mechanical structures is extremely challenging. A new concept to tackle this issue is currently under development at the FH Aachen University of Applied Sciences. The concept "Infused Thermal Solutions (ITS)" is based on the idea to 3D print metallic structures in their regular functional shape, but double walled with internal lattice support structures, allowing the infusion of a PCM layer directly into the voids and eliminating the need for additional parts and interfaces. Together with OHB System, FH Aachen theoretically studied the application of this technology to the Meteosat Third Generation (MTG) Infra-Red Sounder (IRS) instrument. The study focuses on the scan cavity and entrance baffling assembly (EBA) of the IRS. It consists of thermal analyses, 3D-redesign and bread boarding of a scaled and PCM infused EBA version. In the thermal design of the alternative EBA, PCM was applied directly into the EBA, simulating the worst hot case sun intrusion of the mission. By applying 4kg of PCM (to a 60kg baffle) the EBA temperature excursions during sun intrusion were limited from 140K to 30K, leading to a significant thermo-opto-elastic performance gain. This paper introduces the ITS concept development status.},
  language  = {en}
}
@misc{ReiswichBrandtCzupalla2019,
  author    = {Reiswich, Martin and Brandt, Hannes and Czupalla, Markus},
  title     = {Passive thermal control by integration of phase change material into additively manufactured structures},
  series = {E2. 47th Student conference},
  journal   = {E2. 47th Student conference},
  year      = {2019},
  abstract  = {Optical Instruments require an extremely stable thermal surrounding to prevent loss of data quality by misalignments of the instrument components resulting from material deformation due to temperature f luctuations (e.g. from solar intrusion). Phase Change Material (PCM) can be applied as a thermal damper to achieve a more uniform temperature distribution. The challenge of this method is, among others, the integration of PCM into affected areas. If correctly designed, incoming heat is latently absorbed during phase change of the PCM, i.e. the temperature of a structure remains almost constant. In a cold phase, the heat during phase change is released again latently until the PCM returns to its original state of aggregation. Thus, the structure is thermally stabilized. At FH Aachen- University of Applied Sciences research is conducted to apply PCM directly into the structures of affected components (baffles, optical benches, electronic boxes, etc.). Through the application of Additive Manufacturing, the necessary voids are directly printed into these structures and filled later with PCM. Additive Manufacturing enables complex structures that would not have been possible with conservative manufacturing methods. A corresponding Breadboard was developed and manufactured by Selective Laser Melting (SLM). The current state of research includes the handling and analysis of the Breadboard, tests and a correlation of the thermal model. The results have shown analytically and practically that it is possible to use PCM as an integral part of the structure as a thermal damper. The results serve as a basis for the further development of the technology, which should maximize performance and enable the integration of PCM into much more complex structures.},
  language  = {en}
}
@inproceedings{SchildtMarzoccaBraunetal.2019,
  author    = {Schildt, Philipp and Marzocca, Pier and Braun, Carsten and Dahmann, Peter and Keimer, Jona},
  title     = {Effects of atmospheric excitation on vibration based condition monitoring methods for hybrid-electric aircraft propulsion systems},
  series = {AIAC 2018: 18th Australian International Aerospace Congress: HUMS - 11th Defence Science and Technology (DST) International Conference on Health and Usage Monitoring (HUMS 2019): ISSFD - 27th International Symposium on Space Flight Dynamics (ISSFD)},
  booktitle = {AIAC 2018: 18th Australian International Aerospace Congress: HUMS - 11th Defence Science and Technology (DST) International Conference on Health and Usage Monitoring (HUMS 2019): ISSFD - 27th International Symposium on Space Flight Dynamics (ISSFD)},
  isbn      = {9781925627213},
  pages     = {923 -- 928},
  year      = {2019},
  language  = {en}
}