@article{ButenwegKuhlmannBettzieche2005, author = {Butenweg, Christoph and Kuhlmann, Wolfram and Bettzieche, V.}, title = {Baudynamische Untersuchung von Talsperren}, series = {Bauingenieur : die richtungsweisende Zeitschrift im Bauingenieurswesen ; offizielle Zeitschrift der VDI-Gesellschaft Bautechnik. Beilage: D-A-CH-Mitteilungsblatt}, volume = {Band 80}, journal = {Bauingenieur : die richtungsweisende Zeitschrift im Bauingenieurswesen ; offizielle Zeitschrift der VDI-Gesellschaft Bautechnik. Beilage: D-A-CH-Mitteilungsblatt}, number = {Nr. 3}, issn = {0005-6650 (Print) ; 1436-4867 (E-Journal) ; 1434-6591 (Beilage)}, pages = {S2 -- S6}, year = {2005}, language = {de} } @article{MuellerBeckersMussmannetal.2018, author = {M{\"u}ller, Janina and Beckers, Mario and Mußmann, Nina and Bongaerts, Johannes and B{\"u}chs, Jochen}, title = {Elucidation of auxotrophic deficiencies of Bacillus pumilus DSM 18097 to develop a defined minimal medium}, series = {Microbial Cell Factories}, volume = {17}, journal = {Microbial Cell Factories}, number = {1}, publisher = {BioMed Central}, issn = {1475-2859}, doi = {10.1186/s12934-018-0956-1}, pages = {Article No. 106}, year = {2018}, abstract = {Background Culture media containing complex compounds like yeast extract or peptone show numerous disadvantages. The chemical composition of the complex compounds is prone to significant variations from batch to batch and quality control is difficult. Therefore, the use of chemically defined media receives more and more attention in commercial fermentations. This concept results in better reproducibility, it simplifies downstream processing of secreted products and enable rapid scale-up. Culturing bacteria with unknown auxotrophies in chemically defined media is challenging and often not possible without an extensive trial-and-error approach. In this study, a respiration activity monitoring system for shake flasks and its recent version for microtiter plates were used to clarify unknown auxotrophic deficiencies in the model organism Bacillus pumilus DSM 18097. Results Bacillus pumilus DSM 18097 was unable to grow in a mineral medium without the addition of complex compounds. Therefore, a rich chemically defined minimal medium was tested containing basically all vitamins, amino acids and nucleobases, which are essential ingredients of complex components. The strain was successfully cultivated in this medium. By monitoring of the respiration activity, nutrients were supplemented to and omitted from the rich chemically defined medium in a rational way, thus enabling a systematic and fast determination of the auxotrophic deficiencies. Experiments have shown that the investigated strain requires amino acids, especially cysteine or histidine and the vitamin biotin for growth. Conclusions The introduced method allows an efficient and rapid identification of unknown auxotrophic deficiencies and can be used to develop a simple chemically defined tailor-made medium. B. pumilus DSM 18097 was chosen as a model organism to demonstrate the method. However, the method is generally suitable for a wide range of microorganisms. By combining a systematic combinatorial approach based on monitoring the respiration activity with cultivation in microtiter plates, high throughput experiments with high information content can be conducted. This approach facilitates media development, strain characterization and cultivation of fastidious microorganisms in chemically defined minimal media while simultaneously reducing the experimental effort.}, language = {en} } @article{KochBoehnischVerdoncketal.2024, author = {Koch, Christopher and B{\"o}hnisch, Nils and Verdonck, Hendrik and Hach, Oliver and Braun, Carsten}, title = {Comparison of unsteady low- and mid-fidelity propeller aerodynamic methods for whirl flutter applications}, series = {Applied Sciences}, volume = {14}, journal = {Applied Sciences}, number = {2}, publisher = {MDPI}, address = {Basel}, issn = {2076-3417}, doi = {10.3390/app14020850}, pages = {1 -- 28}, year = {2024}, abstract = {Aircraft configurations with propellers have been drawing more attention in recent times, partly due to new propulsion concepts based on hydrogen fuel cells and electric motors. These configurations are prone to whirl flutter, which is an aeroelastic instability affecting airframes with elastically supported propellers. It commonly needs to be mitigated already during the design phase of such configurations, requiring, among other things, unsteady aerodynamic transfer functions for the propeller. However, no comprehensive assessment of unsteady propeller aerodynamics for aeroelastic analysis is available in the literature. This paper provides a detailed comparison of nine different low- to mid-fidelity aerodynamic methods, demonstrating their impact on linear, unsteady aerodynamics, as well as whirl flutter stability prediction. Quasi-steady and unsteady methods for blade lift with or without coupling to blade element momentum theory are evaluated and compared to mid-fidelity potential flow solvers (UPM and DUST) and classical, derivative-based methods. Time-domain identification of frequency-domain transfer functions for the unsteady propeller hub loads is used to compare the different methods. Predictions of the minimum required pylon stiffness for stability show good agreement among the mid-fidelity methods. The differences in the stability predictions for the low-fidelity methods are higher. Most methods studied yield a more unstable system than classical, derivative-based whirl flutter analysis, indicating that the use of more sophisticated aerodynamic modeling techniques might be required for accurate whirl flutter prediction.}, language = {en} } @article{ScheeleBongaertsMaureretal.2009, author = {Scheele, S. and Bongaerts, Johannes and Maurer, K.-H. and Freudl, R.}, title = {Sekretion einer Kofaktor-haltigen Oxidase durch Corynebacterium glutamicum}, series = {Chemie - Ingenieur - Technik (CIT)}, volume = {Vol. 81}, journal = {Chemie - Ingenieur - Technik (CIT)}, number = {Iss. 8}, issn = {1522-2640 (E-Journal); 0009-286X (Print)}, pages = {1309}, year = {2009}, language = {de} } @article{ChudobaButenwegPeiffer2004, author = {Chudoba, Rostislav and Butenweg, Christoph and Peiffer, F.}, title = {Technical information system for collaborative material research}, series = {Advances in engineering software}, volume = {Volume 35}, journal = {Advances in engineering software}, number = {Issue 10-11}, issn = {1873-5339 (E-Journal); 0965-9978 (Print)}, doi = {10.1016/j.advengsoft.2004.03.021}, pages = {747 -- 756}, year = {2004}, language = {en} } @article{Bung2021, author = {Bung, Daniel Bernhard}, title = {Extreme flooding in Western Germany: some thoughts on hazards, return periods and risk}, series = {Hydrolink}, journal = {Hydrolink}, number = {4}, publisher = {International Association for Hydro-Environment Engineering and Research (IAHR)}, address = {Madrid}, pages = {108 -- 113}, year = {2021}, abstract = {The low-pressure system Bernd involved extreme rainfalls in the Western part of Germany in July 2021, resulting in major floods, severe damages and a tremendous number of casualties. Such extreme events are rare and full flood protection can never be ensured with reasonable financial means. But still, this event must be starting point to reconsider current design concepts. This article aims at sharing some thoughts on potential hazards, the selection of return periods and remaining risk with the focus on Germany.}, language = {en} } @article{KuhlmannButenwegMeskouris2003, author = {Kuhlmann, Wolfram and Butenweg, Christoph and Meskouris, Konstantin}, title = {Baudynamische Untersuchung des Aachener Doms unter Erdbebenbelastung}, series = {Bautechnik : Zeitschrift f{\"u}r den gesamten Ingenieurbau}, volume = {Vol. 80}, journal = {Bautechnik : Zeitschrift f{\"u}r den gesamten Ingenieurbau}, number = {Iss. 10}, issn = {1437-0999 (E-Journal); 0005-6820 (Print); 0932-8351 (Print)}, doi = {10.1002/bate.200305080}, pages = {675 -- 684}, year = {2003}, language = {de} } @article{FalkenbergKohnBottetal.2023, author = {Falkenberg, Fabian and Kohn, Sophie and Bott, Michael and Bongaerts, Johannes and Siegert, Petra}, title = {Biochemical characterisation of a novel broad pH spectrum subtilisin from Fictibacillus arsenicus DSM 15822ᵀ}, series = {FEBS Open Bio}, volume = {13}, journal = {FEBS Open Bio}, number = {11}, publisher = {Wiley}, address = {Hoboken, NJ}, issn = {2211-5463}, doi = {10.1002/2211-5463.13701}, pages = {2035 -- 2046}, year = {2023}, abstract = {Subtilisins from microbial sources, especially from the Bacillaceae family, are of particular interest for biotechnological applications and serve the currently growing enzyme market as efficient and novel biocatalysts. Biotechnological applications include use in detergents, cosmetics, leather processing, wastewater treatment and pharmaceuticals. To identify a possible candidate for the enzyme market, here we cloned the gene of the subtilisin SPFA from Fictibacillus arsenicus DSM 15822ᵀ (obtained through a data mining-based search) and expressed it in Bacillus subtilis DB104. After production and purification, the protease showed a molecular mass of 27.57 kDa and a pI of 5.8. SPFA displayed hydrolytic activity at a temperature optimum of 80 °C and a very broad pH optimum between 8.5 and 11.5, with high activity up to pH 12.5. SPFA displayed no NaCl dependence but a high NaCl tolerance, with decreasing activity up to concentrations of 5 m NaCl. The stability enhanced with increasing NaCl concentration. Based on its substrate preference for 10 synthetic peptide 4-nitroanilide substrates with three or four amino acids and its phylogenetic classification, SPFA can be assigned to the subgroup of true subtilisins. Moreover, SPFA exhibited high tolerance to 5\% (w/v) SDS and 5\% H₂O₂ (v/v). The biochemical properties of SPFA, especially its tolerance of remarkably high pH, SDS and H₂O₂, suggest it has potential for biotechnological applications.}, language = {en} } @article{RachingerBauchStrittmatteretal.2013, author = {Rachinger, Michael and Bauch, Melanie and Strittmatter, Axel and Bongaerts, Johannes and Evers, Stefan and Maurer, Karl-Heinz and Daniel, Rolf and Liebl, Wolfgang and Liesegang, Heiko and Ehrenreich, Armin}, title = {Size unlimited markerless deletions by a transconjugative plasmid-system in Bacillus licheniformis}, series = {Journal of biotechnology}, volume = {Vol. 164}, journal = {Journal of biotechnology}, number = {Iss. 4}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1873-4863 (E-Journal); 0168-1656 (Print)}, pages = {365 -- 369}, year = {2013}, language = {en} } @article{Bung2011, author = {Bung, Daniel Bernhard}, title = {Developing flow in skimming flow regime on embankment stepped spillways}, series = {Journal of hydraulic research}, volume = {Vol. 49}, journal = {Journal of hydraulic research}, number = {Iss. 5}, publisher = {Taylor \& Francis}, address = {London}, issn = {1814-2079 (E-Journal); 0022-1686 (Print)}, pages = {639 -- 648}, year = {2011}, language = {en} } @article{WissenbachSixBongaertsetal.1995, author = {Wissenbach, U. and Six, S. and Bongaerts, Johannes and Ternes, D. and Steinwachs, S. and Unden, G.}, title = {A third periplasmic transport system for l-arginine in Escherichia coli: molecular characterization of the artPIQMJ genes, arginine binding and transport}, series = {Molecular microbiology}, volume = {Vol. 17}, journal = {Molecular microbiology}, number = {Iss. 4}, issn = {1365-2958 (E-Journal); 0950-382x (Print)}, pages = {675 -- 686}, year = {1995}, language = {en} } @article{WoliszSchuetzBlankeetal.2017, author = {Wolisz, Henryk and Sch{\"u}tz, Thomas and Blanke, Tobias and Hagenkamp, Markus and Kohrn, Markus and Wesseling, Mark and M{\"u}ller, Dirk}, title = {Cost optimal sizing of smart buildings' energy system components considering changing end-consumer electricity markets}, series = {Energy}, volume = {137}, journal = {Energy}, publisher = {Elsevier}, address = {Amsterdam}, doi = {10.1016/j.energy.2017.06.025}, pages = {715 -- 728}, year = {2017}, language = {en} } @article{LehnertzAnsmannBialonskietal.2014, author = {Lehnertz, Klaus and Ansmann, Gerrit and Bialonski, Stephan and Dickten, Henning and Geier, Christian and Porz, Stephan}, title = {Evolving networks in the human epileptic brain}, series = {Physica D: Nonlinear Phenomena}, volume = {267}, journal = {Physica D: Nonlinear Phenomena}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0167-2789}, doi = {10.1016/j.physd.2013.06.009}, pages = {7 -- 15}, year = {2014}, abstract = {Network theory provides novel concepts that promise an improved characterization of interacting dynamical systems. Within this framework, evolving networks can be considered as being composed of nodes, representing systems, and of time-varying edges, representing interactions between these systems. This approach is highly attractive to further our understanding of the physiological and pathophysiological dynamics in human brain networks. Indeed, there is growing evidence that the epileptic process can be regarded as a large-scale network phenomenon. We here review methodologies for inferring networks from empirical time series and for a characterization of these evolving networks. We summarize recent findings derived from studies that investigate human epileptic brain networks evolving on timescales ranging from few seconds to weeks. We point to possible pitfalls and open issues, and discuss future perspectives.}, language = {en} } @article{ButenwegRosinHoller2017, author = {Butenweg, Christoph and Rosin, Julia and Holler, Stefan}, title = {Analysis of cylindrical granular material silos under seismic excitation}, series = {Buildings}, volume = {7}, journal = {Buildings}, number = {3}, publisher = {MDPI}, address = {Basel}, issn = {2075-5309}, doi = {10.3390/buildings7030061}, pages = {1 -- 12}, year = {2017}, abstract = {Silos generally work as storage structures between supply and demand for various goods, and their structural safety has long been of interest to the civil engineering profession. This is especially true for dynamically loaded silos, e.g., in case of seismic excitation. Particularly thin-walled cylindrical silos are highly vulnerable to seismic induced pressures, which can cause critical buckling phenomena of the silo shell. The analysis of silos can be carried out in two different ways. In the first, the seismic loading is modeled through statically equivalent loads acting on the shell. Alternatively, a time history analysis might be carried out, in which nonlinear phenomena due to the filling as well as the interaction between the shell and the granular material are taken into account. The paper presents a comparison of these approaches. The model used for the nonlinear time history analysis considers the granular material by means of the intergranular strain approach for hypoplasticity theory. The interaction effects between the granular material and the shell is represented by contact elements. Additionally, soil-structure interaction effects are taken into account.}, language = {en} } @article{GrundmannDachwaldGrimmetal.2015, author = {Grundmann, Jan Thimo and Dachwald, Bernd and Grimm, Christian D. and Kahle, Ralph and Koch, Aaron Dexter and Krause, Christian and Lange, Caroline and Quantius, Dominik and Ulamec, Stephan}, title = {Spacecraft for Hypervelocity Impact Research - An Overview of Capabilities, Constraints and the Challenges of Getting There}, series = {Procedia Engineering}, volume = {Vol. 103}, journal = {Procedia Engineering}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1877-7058}, doi = {10.1016/j.proeng.2015.04.021}, pages = {151 -- 158}, year = {2015}, language = {en} } @article{ArtmannZerlinDigel2008, author = {Artmann, Gerhard and Zerlin, Kay and Digel, Ilya}, title = {Hemoglobin Senses Body Temperature}, series = {Bioengineering in Cell and Tissue Research / Artmann, Gerhard M. ; Chien, Shu (Eds.)}, journal = {Bioengineering in Cell and Tissue Research / Artmann, Gerhard M. ; Chien, Shu (Eds.)}, publisher = {Springer}, address = {Berlin}, isbn = {978-3-540-75408-4}, pages = {415 -- 447}, year = {2008}, language = {en} } @article{DachwaldMengaliQuartaetal.2007, author = {Dachwald, Bernd and Mengali, Giovanni and Quarta, Alessandro A. and Circi, Christian}, title = {Refined Solar Sail Force Model with Mission Application / Giovanni Mengali ; Alessandro A. Quarta , Christian Circi ; Bernd Dachwald}, series = {Journal of Guidance, Control, and Dynamics. 30 (2007), H. 2}, journal = {Journal of Guidance, Control, and Dynamics. 30 (2007), H. 2}, isbn = {0162-3192}, pages = {512 -- 520}, year = {2007}, language = {en} } @article{MistlerButenwegFehlingetal.2007, author = {Mistler, Michael and Butenweg, Christoph and Fehling, Ekkehard and St{\"u}rz, Jochen}, title = {Verformungsbasierte seismische Bemessung von Mauerwerksbauten auf Grundlage zyklischer Schubwandversuche}, series = {Bauingenieur : die richtungsweisende Zeitschrift im Bauingenieurswesen ; offizielle Zeitschrift der VDI-Gesellschaft Bautechnik. Beilage: D-A-CH-Mitteilungsblatt}, volume = {Band 82}, journal = {Bauingenieur : die richtungsweisende Zeitschrift im Bauingenieurswesen ; offizielle Zeitschrift der VDI-Gesellschaft Bautechnik. Beilage: D-A-CH-Mitteilungsblatt}, issn = {1434-6591}, pages = {S3 -- S11}, year = {2007}, language = {de} } @article{BeckerDelfmannDietrichetal.2016, author = {Becker, J{\"o}rg and Delfmann, Patrick and Dietrich, Hanns-Alexander and Steinhorst, Matthias and Eggert, Mathias}, title = {Business Process Compliance Checking — Applying and Evaluating a Generic Pattern Matching Approach for Conceptual Models in the Financial Sector}, series = {Information Systems Frontiers}, volume = {18}, journal = {Information Systems Frontiers}, number = {2}, publisher = {Springer}, address = {Berlin}, issn = {1572-9419}, doi = {10.1007/s10796-014-9529-y}, pages = {359 -- 405}, year = {2016}, abstract = {Given the strong increase in regulatory requirements for business processes the management of business process compliance becomes a more and more regarded field in IS research. Several methods have been developed to support compliance checking of conceptual models. However, their focus on distinct modeling languages and mostly linear (i.e., predecessor-successor related) compliance rules may hinder widespread adoption and application in practice. Furthermore, hardly any of them has been evaluated in a real-world setting. We address this issue by applying a generic pattern matching approach for conceptual models to business process compliance checking in the financial sector. It consists of a model query language, a search algorithm and a corresponding modelling tool prototype. It is (1) applicable for all graph-based conceptual modeling languages and (2) for different kinds of compliance rules. Furthermore, based on an applicability check, we (3) evaluate the approach in a financial industry project setting against its relevance for decision support of audit and compliance management tasks.}, language = {en} } @article{BackesAdamGottschaldetal.2012, author = {Backes, Klaus and Adam, Mario and Gottschald, Beng Jonas and Faber, Christian and Henneb{\"o}hl, Friedrich-Gregor and Lanz, Marco and Anthrakidis, Anette}, title = {KWKK-Anlagen im Feldtest. Optimaler Betrieb durch Verbesserungen bei Regelung und Hydraulik}, series = {Die K{\"a}lte- und Klimatechnik}, journal = {Die K{\"a}lte- und Klimatechnik}, number = {2}, publisher = {Gentner}, address = {Stuttgart}, issn = {0343-2246}, year = {2012}, language = {de} }