@article{WolfFoltzSchlicketal.2002, author = {Wolf, Martin R. and Foltz, Christian and Schlick, Christopher and Luczak, Holger}, title = {Development and evaluation of a groupware system to support chemical design processes / Wolf, Martin ; Foltz, Christian ; Schlick, Christopher ; Luczak, Holger}, series = {International Journal of Human-Computer Interaction . 14 (2002), H. 2}, journal = {International Journal of Human-Computer Interaction . 14 (2002), H. 2}, publisher = {-}, isbn = {1044-7318}, pages = {181 -- 198}, year = {2002}, language = {en} } @article{BongaertsZoschkeWeidneretal.1995, author = {Bongaerts, Johannes and Zoschke, Sascha and Weidner, Uwe and Linden, Gottfried}, title = {Transcriptional regulation of the proton translocating NADH}, series = {Molecular microbiology}, volume = {Vol. 16}, journal = {Molecular microbiology}, number = {Iss. 3}, issn = {1365-2958 (E-Journal); 0950-382x (Print)}, pages = {521 -- 534}, year = {1995}, language = {en} } @article{Staat1996, author = {Staat, Manfred}, title = {Problems and Chances for Probabilistic Fracture Mechanics in the Analysis of Steel Pressure Boundary Reliability}, series = {Technical feasibility and reliability of passive safety systems for nuclear power plants. Proceedings of an Advisory Group Meeting held in J{\"u}lich, 21-24 November 1994}, journal = {Technical feasibility and reliability of passive safety systems for nuclear power plants. Proceedings of an Advisory Group Meeting held in J{\"u}lich, 21-24 November 1994}, address = {Vienna}, pages = {43 -- 55}, year = {1996}, language = {en} } @article{Stulpe1988, author = {Stulpe, Werner}, title = {Conditional Expectations, Conditional Distributions, and A Posteriori Ensembles in Generalized Probability Theory}, series = {International Journal of Theoretical Physics. 27 (1988), H. 5}, journal = {International Journal of Theoretical Physics. 27 (1988), H. 5}, isbn = {1572-9575}, pages = {587 -- 611}, year = {1988}, language = {en} } @article{Laack1986, author = {Laack, Walter van}, title = {Allgemeine physiotherapeutische Behandlung nach H{\"u}ft- und Kniegelenkoperationen}, series = {Physiotherapie. 77 (1986), H. 2}, journal = {Physiotherapie. 77 (1986), H. 2}, isbn = {0031-9392}, pages = {68 -- 72}, year = {1986}, language = {de} } @article{Golland2019, author = {Golland, Alexander}, title = {Reichweite des "Joint Controllership": Neue Fragen der gemeinsamen Verantwortlichkeit}, series = {K\&R Kommunikation \& Recht}, volume = {22}, journal = {K\&R Kommunikation \& Recht}, number = {9}, publisher = {dfv Mediengruppe, Deutscher Fachverlag GmbH}, address = {Frankfurt am Main}, issn = {1434-6354}, pages = {533 -- 537}, year = {2019}, abstract = {Kein Urteil zum Datenschutzrecht sorgte im vergangenen Jahr f{\"u}r mehr panische Reaktionen als die Entscheidung des EuGH in der Rechtssache "Wirtschaftsakademie Schleswig-Holstein"(C-210/16). Das Urteil warf in datenschutzrechtlicher Literatur und {\"O}ffentlichkeit zahlreiche Fragen auf: Ist jetzt jeder "gemeinsam" Verantwortlicher? Was sind die Kriterien? Der EuGH hat k{\"u}rzlich in einem - dem allgemeinen Vernehmen nach aufsehenerregenden, de facto aber kaum {\"u}berraschenden - Urteil f{\"u}r Klarheit gesorgt. Dabei hat das Gericht jedoch einige Fragen offengelassen und neue Fragen aufgeworfen. Ein Blick auf alte und neue Herausforderungen in Kooperationsszenarien.}, language = {de} } @article{JanusAchtsnichtDrinicetal.2023, author = {Janus, Kevin Alexander and Achtsnicht, Stefan and Drinic, Aleksander and Kopp, Alexander and Keusgen, Michael and Sch{\"o}ning, Michael Josef}, title = {Transient magnesium-based thin-film temperature sensor on a flexible, bioabsorbable substrate for future medical applications}, series = {Applied Research}, journal = {Applied Research}, number = {Accepted manuscript}, publisher = {Wiley-VCH}, issn = {2702-4288 (Print)}, doi = {10.1002/appl.202300102}, pages = {22 Seiten}, year = {2023}, abstract = {In this work, the bioabsorbable materials, namely fibroin, polylactide acid (PLA), magnesium and magnesium oxide are investigated for their application as transient, resistive temperature detectors (RTD). For this purpose, a thin-film magnesium-based meander-like electrode is deposited onto a flexible, bioabsorbable substrate (fibroin or PLA) and encapsulated (passivated) by additional magnesium oxide layers on top and below the magnesium-based electrode. The morphology of different layered RTDs is analyzed by scanning electron microscopy. The sensor performance and lifetime of the RTD is characterized both under ambient atmospheric conditions between 30°C and 43°C, and wet tissue-like conditions with a constant temperature regime of 37°C. The latter triggers the degradation process of the magnesium-based layers. The 3-layers RTDs on a PLA substrate could achieve a lifetime of 8.5 h. These sensors also show the best sensor performance under ambient atmospheric conditions with a mean sensitivity of 0.48 Ω/°C ± 0.01 Ω/°C.}, language = {en} } @article{JanusAchtsnichtTempeletal.2023, author = {Janus, Kevin Alexander and Achtsnicht, Stefan and Tempel, Laura and Drinic, Aleksaner and Kopp, Alexander and Keusgen, Michael and Sch{\"o}ning, Michael Josef}, title = {Influence of fibroin membrane composition and curing parameters on the performance of a biodegradable enzymatic biosensor manufactured from Silicon-Free Carbon}, series = {Physica status solidi : pss. A, Applications and materials science}, volume = {220}, journal = {Physica status solidi : pss. A, Applications and materials science}, number = {22}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {1862-6300 (Print)}, doi = {10.1002/pssa.202300081}, pages = {10 Seiten}, year = {2023}, abstract = {Herein, fibroin, polylactide (PLA), and carbon are investigated for their suitability as biocompatible and biodegradable materials for amperometric biosensors. For this purpose, screen-printed carbon electrodes on the biodegradable substrates fibroin and PLA are modified with a glucose oxidase membrane and then encapsulated with the biocompatible material Ecoflex. The influence of different curing parameters of the carbon electrodes on the resulting biosensor characteristics is studied. The morphology of the electrodes is investigated by scanning electron microscopy, and the biosensor performance is examined by amperometric measurements of glucose (0.5-10 mM) in phosphate buffer solution, pH 7.4, at an applied potential of 1.2 V versus a Ag/AgCl reference electrode. Instead of Ecoflex, fibroin, PLA, and wound adhesive are tested as alternative encapsulation compounds: a series of swelling tests with different fibroin compositions, PLA, and Ecoflex has been performed before characterizing the most promising candidates by chronoamperometry. Therefore, the carbon electrodes are completely covered with the particular encapsulation material. Chronoamperometric measurements with H2O2 concentrations between 0.5 and 10 mM enable studying the leakage current behavior.}, language = {en} } @article{KarschuckPoghossianSeretal.2024, author = {Karschuck, Tobias and Poghossian, Arshak and Ser, Joey and Tsokolakyan, Astghik and Achtsnicht, Stefan and Wagner, Patrick and Sch{\"o}ning, Michael Josef}, title = {Capacitive model of enzyme-modified field-effect biosensors: Impact of enzyme coverage}, series = {Sensors and Actuators B: Chemical}, volume = {408}, journal = {Sensors and Actuators B: Chemical}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0925-4005 (Print)}, doi = {10.1016/j.snb.2024.135530}, pages = {12 Seiten}, year = {2024}, abstract = {Electrolyte-insulator-semiconductor capacitors (EISCAP) belong to field-effect sensors having an attractive transducer architecture for constructing various biochemical sensors. In this study, a capacitive model of enzyme-modified EISCAPs has been developed and the impact of the surface coverage of immobilized enzymes on its capacitance-voltage and constant-capacitance characteristics was studied theoretically and experimentally. The used multicell arrangement enables a multiplexed electrochemical characterization of up to sixteen EISCAPs. Different enzyme coverages have been achieved by means of parallel electrical connection of bare and enzyme-covered single EISCAPs in diverse combinations. As predicted by the model, with increasing the enzyme coverage, both the shift of capacitance-voltage curves and the amplitude of the constant-capacitance signal increase, resulting in an enhancement of analyte sensitivity of the EISCAP biosensor. In addition, the capability of the multicell arrangement with multi-enzyme covered EISCAPs for sequentially detecting multianalytes (penicillin and urea) utilizing the enzymes penicillinase and urease has been experimentally demonstrated and discussed.}, language = {en} } @article{MonakhovaDiehl2021, author = {Monakhova, Yulia and Diehl, Bernd W.K.}, title = {Novel approach of qNMR workflow by standardization using 2H integral: Application to any intrinsic calibration standard}, series = {Talanta}, volume = {222}, journal = {Talanta}, number = {Article number: 121504}, publisher = {Elsevier}, isbn = {0039-9140}, doi = {10.1016/j.talanta.2020.121504}, year = {2021}, abstract = {Quantitative nuclear magnetic resonance (qNMR) is routinely performed by the internal or external standardization. The manuscript describes a simple alternative to these common workflows by using NMR signal of another active nuclei of calibration compound. For example, for any arbitrary compound quantification by NMR can be based on the use of an indirect concentration referencing that relies on a solvent having both 1H and 2H signals. To perform high-quality quantification, the deuteration level of the utilized deuterated solvent has to be estimated. In this contribution the new method was applied to the determination of deuteration levels in different deuterated solvents (MeOD, ACN, CDCl3, acetone, benzene, DMSO-d6). Isopropanol-d6, which contains a defined number of deuterons and protons, was used for standardization. Validation characteristics (precision, accuracy, robustness) were calculated and the results showed that the method can be used in routine practice. Uncertainty budget was also evaluated. In general, this novel approach, using standardization by 2H integral, benefits from reduced sample preparation steps and uncertainties, and can be applied in different application areas (purity determination, forensics, pharmaceutical analysis, etc.).}, language = {en} }