@article{HuckPoghossianWagneretal.2012,
  author    = {Huck, Christina and Poghossian, Arshak and Wagner, Patrick and Sch{\"o}ning, Michael Josef},
  title     = {Combined amperometric/field-effect sensor for the detection of dissolved hydrogen},
  series = {Sensors and actuators B: Chemical},
  volume    = {187},
  journal   = {Sensors and actuators B: Chemical},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0925-4005},
  doi       = {10.1016/j.snb.2012.10.050},
  pages     = {168 -- 173},
  year      = {2012},
  abstract  = {Real-time and reliable monitoring of the biogas process is crucial for a stable and efficient operation of biogas production in order to avoid digester breakdowns. The concentration of dissolved hydrogen (H₂) represents one of the key parameters for biogas process control. In this work, a one-chip integrated combined amperometric/field-effect sensor for monitoring the dissolved H₂ concentration has been developed for biogas applications. The combination of two different transducer principles might allow a more accurate and reliable measurement of dissolved H₂ as an early warning indicator of digester failures. The feasibility of the approach has been demonstrated by simultaneous amperometric/field-effect measurements of dissolved H₂ concentrations in electrolyte solutions. Both, the amperometric and the field-effect transducer show a linear response behaviour in the H₂ concentration range from 0.1 to 3\% (v/v) with a slope of 198.4 ± 13.7 nA/\% (v/v) and 14.9 ± 0.5 mV/\% (v/v), respectively.},
  language  = {en}
}
@article{HuckSchiffelsHerreraetal.2013,
  author    = {Huck, Christina and Schiffels, Johannes and Herrera, Cony N. and Schelden, Maximilian and Selmer, Thorsten and Poghossian, Arshak and Baumann, Marcus and Wagner, Patrick and Sch{\"o}ning, Michael Josef},
  title     = {Metabolic responses of Escherichia coli upon glucose pulses captured by a capacitive field-effect sensor},
  series = {Physica Status Solidi (A)},
  volume    = {210},
  journal   = {Physica Status Solidi (A)},
  number    = {5},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {0031-8965},
  doi       = {10.1002/pssa.201200900},
  pages     = {926 -- 931},
  year      = {2013},
  abstract  = {Living cells are complex biological systems transforming metabolites taken up from the surrounding medium. Monitoring the responses of such cells to certain substrate concentrations is a challenging task and offers possibilities to gain insight into the vitality of a community influenced by the growth environment. Cell-based sensors represent a promising platform for monitoring the metabolic activity and thus, the "welfare" of relevant organisms. In the present study, metabolic responses of the model bacterium Escherichia coli in suspension, layered onto a capacitive field-effect structure, were examined to pulses of glucose in the concentration range between 0.05 and 2 mM. It was found that acidification of the surrounding medium takes place immediately after glucose addition and follows Michaelis-Menten kinetic behavior as a function of the glucose concentration. In future, the presented setup can, therefore, be used to study substrate specificities on the enzymatic level and may as well be used to perform investigations of more complex metabolic responses. Conclusions and perspectives highlighting this system are discussed.},
  language  = {en}
}
@article{IngebrandtHanNakamuraetal.2007,
  author    = {Ingebrandt, S. and Han, Y. and Nakamura, F. and Poghossian, Arshak and Sch{\"o}ning, Michael Josef and Offenh{\"a}usser, A.},
  title     = {Label-free detection of single nucleotide polymorphisms utilizing the differential transfer function of field-effect transistors},
  series = {Biosensors and Bioelectronics. 22 (2007), H. 12},
  journal   = {Biosensors and Bioelectronics. 22 (2007), H. 12},
  isbn      = {0956-5663},
  pages     = {2834 -- 2840},
  year      = {2007},
  language  = {en}
}
@inproceedings{JablonskiKochBronderetal.2017,
  author    = {Jablonski, Melanie and Koch, Claudia and Bronder, Thomas and Poghossian, Arshak and Wege, Christina and Sch{\"o}ning, Michael Josef},
  title     = {Field-Effect Biosensors Modified with Tobacco Mosaic Virus Nanotubes as Enzyme Nanocarrier},
  series = {MDPI Proceeding},
  volume    = {1},
  booktitle = {MDPI Proceeding},
  number    = {4},
  doi       = {10.3390/proceedings1040505},
  pages     = {4},
  year      = {2017},
  language  = {en}
}
@article{JablonskiPoghossianKeusgenetal.2021,
  author    = {Jablonski, Melanie and Poghossian, Arshak and Keusgen, Michael and Wege, Christina and Sch{\"o}ning, Michael Josef},
  title     = {Detection of plant virus particles with a capacitive field-effect sensor},
  series = {Analytical and Bioanalytical Chemistry},
  volume    = {413},
  journal   = {Analytical and Bioanalytical Chemistry},
  publisher = {Springer Nature},
  address   = {Cham},
  issn      = {1618-2650},
  doi       = {10.1007/s00216-021-03448-8},
  pages     = {5669 -- 5678},
  year      = {2021},
  abstract  = {Plant viruses are major contributors to crop losses and induce high economic costs worldwide. For reliable, on-site and early detection of plant viral diseases, portable biosensors are of great interest. In this study, a field-effect SiO2-gate electrolyte-insulator-semiconductor (EIS) sensor was utilized for the label-free electrostatic detection of tobacco mosaic virus (TMV) particles as a model plant pathogen. The capacitive EIS sensor has been characterized regarding its TMV sensitivity by means of constant-capacitance method. The EIS sensor was able to detect biotinylated TMV particles from a solution with a TMV concentration as low as 0.025 nM. A good correlation between the registered EIS sensor signal and the density of adsorbed TMV particles assessed from scanning electron microscopy images of the SiO2-gate chip surface was observed. Additionally, the isoelectric point of the biotinylated TMV particles was determined via zeta potential measurements and the influence of ionic strength of the measurement solution on the TMV-modified EIS sensor signal has been studied.},
  language  = {en}
}
@article{JablonskiPoghossianSeverinetal.2021,
  author    = {Jablonski, Melanie and Poghossian, Arshak and Severin, Robin and Keusgen, Michael and Wege, Christian and Sch{\"o}ning, Michael Josef},
  title     = {Capacitive Field-Effect Biosensor Studying Adsorption of Tobacco Mosaic Virus Particles},
  series = {Micromachines},
  volume    = {12},
  journal   = {Micromachines},
  number    = {1},
  publisher = {MDPI},
  address   = {Basel},
  doi       = {10.3390/mi12010057},
  pages     = {Artikel 57},
  year      = {2021},
  abstract  = {Plant virus-like particles, and in particular, tobacco mosaic virus (TMV) particles, are increasingly being used in nano- and biotechnology as well as for biochemical sensing purposes as nanoscaffolds for the high-density immobilization of receptor molecules. The sensitive parameters of TMV-assisted biosensors depend, among others, on the density of adsorbed TMV particles on the sensor surface, which is affected by both the adsorption conditions and surface properties of the sensor. In this work, Ta₂O₅-gate field-effect capacitive sensors have been applied for the label-free electrical detection of TMV adsorption. The impact of the TMV concentration on both the sensor signal and the density of TMV particles adsorbed onto the Ta₂O₅-gate surface has been studied systematically by means of field-effect and scanning electron microscopy methods. In addition, the surface density of TMV particles loaded under different incubation times has been investigated. Finally, the field-effect sensor also demonstrates the label-free detection of penicillinase immobilization as model bioreceptor on TMV particles.},
  language  = {en}
}
@article{KarschuckKaulenPoghossianetal.2021,
  author    = {Karschuck, Tobias and Kaulen, Corinna and Poghossian, Arshak and Wagner, Patrick H. and Sch{\"o}ning, Michael Josef},
  title     = {Gold nanoparticle-modified capacitive field-effect sensors: Studying the surface density of nanoparticles and coupling of charged polyelectrolyte macromolecules},
  series = {Electrochemical Science Advances},
  volume    = {2},
  journal   = {Electrochemical Science Advances},
  number    = {5},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {0938-5193},
  doi       = {10.1002/elsa.202100179},
  pages     = {10 Seiten},
  year      = {2021},
  abstract  = {The coupling of ligand-stabilized gold nanoparticles with field-effect devices offers new possibilities for label-free biosensing. In this work, we study the immobilization of aminooctanethiol-stabilized gold nanoparticles (AuAOTs) on the silicon dioxide surface of a capacitive field-effect sensor. The terminal amino group of the AuAOT is well suited for the functionalization with biomolecules. The attachment of the positively-charged AuAOTs on a capacitive field-effect sensor was detected by direct electrical readout using capacitance-voltage and constant capacitance measurements. With a higher particle density on the sensor surface, the measured signal change was correspondingly more pronounced. The results demonstrate the ability of capacitive field-effect sensors for the non-destructive quantitative validation of nanoparticle immobilization. In addition, the electrostatic binding of the polyanion polystyrene sulfonate to the AuAOT-modified sensor surface was studied as a model system for the label-free detection of charged macromolecules. Most likely, this approach can be transferred to the label-free detection of other charged molecules such as enzymes or antibodies.},
  language  = {en}
}
@article{KarschuckPoghossianSeretal.2024,
  author    = {Karschuck, Tobias and Poghossian, Arshak and Ser, Joey and Tsokolakyan, Astghik and Achtsnicht, Stefan and Wagner, Patrick and Sch{\"o}ning, Michael Josef},
  title     = {Capacitive model of enzyme-modified field-effect biosensors: Impact of enzyme coverage},
  series = {Sensors and Actuators B: Chemical},
  volume    = {408},
  journal   = {Sensors and Actuators B: Chemical},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0925-4005 (Print)},
  doi       = {10.1016/j.snb.2024.135530},
  pages     = {12 Seiten},
  year      = {2024},
  abstract  = {Electrolyte-insulator-semiconductor capacitors (EISCAP) belong to field-effect sensors having an attractive transducer architecture for constructing various biochemical sensors. In this study, a capacitive model of enzyme-modified EISCAPs has been developed and the impact of the surface coverage of immobilized enzymes on its capacitance-voltage and constant-capacitance characteristics was studied theoretically and experimentally. The used multicell arrangement enables a multiplexed electrochemical characterization of up to sixteen EISCAPs. Different enzyme coverages have been achieved by means of parallel electrical connection of bare and enzyme-covered single EISCAPs in diverse combinations. As predicted by the model, with increasing the enzyme coverage, both the shift of capacitance-voltage curves and the amplitude of the constant-capacitance signal increase, resulting in an enhancement of analyte sensitivity of the EISCAP biosensor. In addition, the capability of the multicell arrangement with multi-enzyme covered EISCAPs for sequentially detecting multianalytes (penicillin and urea) utilizing the enzymes penicillinase and urease has been experimentally demonstrated and discussed.},
  language  = {en}
}
@article{KarschuckSchmidtAchtsnichtetal.2023,
  author    = {Karschuck, Tobias and Schmidt, Stefan and Achtsnicht, Stefan and Poghossian, Arshak and Wagner, Patrick and Sch{\"o}ning, Michael Josef},
  title     = {Multiplexing system for automated characterization of a capacitive field-effect sensor array},
  series = {Physica Status Solidi A},
  volume    = {220},
  journal   = {Physica Status Solidi A},
  number    = {22},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {1862-6300 (Print)},
  doi       = {10.1002/pssa.202300265},
  pages     = {7 Seiten},
  year      = {2023},
  abstract  = {In comparison to single-analyte devices, multiplexed systems for a multianalyte detection offer a reduced assay time and sample volume, low cost, and high throughput. Herein, a multiplexing platform for an automated quasi-simultaneous characterization of multiple (up to 16) capacitive field-effect sensors by the capacitive-voltage (C-V) and the constant-capacitance (ConCap) mode is presented. The sensors are mounted in a newly designed multicell arrangement with one common reference electrode and are electrically connected to the impedance analyzer via the base station. A Python script for the automated characterization of the sensors executes the user-defined measurement protocol. The developed multiplexing system is tested for pH measurements and the label-free detection of ligand-stabilized, charged gold nanoparticles.},
  language  = {en}
}
@article{KassabHanPoghossianetal.2004,
  author    = {Kassab, T. and Han, Y. and Poghossian, Arshak and Ingebrandt, S. and Offenh{\"a}usser, A. and Sch{\"o}ning, Michael Josef},
  title     = {Detection of layerby-layer adsorbed polyelectrolytes by means of field-effect based capacitive EIS structures},
  series = {Biomedizinische Technik. 49 (2004), H. 2},
  journal   = {Biomedizinische Technik. 49 (2004), H. 2},
  isbn      = {0932-4666},
  pages     = {1034 -- 1035},
  year      = {2004},
  language  = {en}
}
@article{KatzPoghossianSchoening2017,
  author    = {Katz, Evgeny and Poghossian, Arshak and Sch{\"o}ning, Michael Josef},
  title     = {Enzyme-based logic gates and circuits - analytical applications and interfacing with electronics},
  series = {Analytical and Bioanalytical Chemistry},
  volume    = {409},
  journal   = {Analytical and Bioanalytical Chemistry},
  publisher = {Springer},
  address   = {Berlin},
  issn      = {1618-2650},
  doi       = {10.1007/s00216-016-0079-7},
  pages     = {81 -- 94},
  year      = {2017},
  abstract  = {The paper is an overview of enzyme-based logic gates and their short circuits, with specific examples of Boolean AND and OR gates, and concatenated logic gates composed of multi-step enzyme-biocatalyzed reactions. Noise formation in the biocatalytic reactions and its decrease by adding a "filter" system, converting convex to sigmoid response function, are discussed. Despite the fact that the enzyme-based logic gates are primarily considered as components of future biomolecular computing systems, their biosensing applications are promising for immediate practical use. Analytical use of the enzyme logic systems in biomedical and forensic applications is discussed and exemplified with the logic analysis of biomarkers of various injuries, e.g., liver injury, and with analysis of biomarkers characteristic of different ethnicity found in blood samples on a crime scene. Interfacing of enzyme logic systems with modified electrodes and semiconductor devices is discussed, giving particular attention to the interfaces functionalized with signal-responsive materials. Future perspectives in the design of the biomolecular logic systems and their applications are discussed in the conclusion.},
  language  = {en}
}
@article{KochPoghossianSchoeningetal.2018,
  author    = {Koch, Claudia and Poghossian, Arshak and Sch{\"o}ning, Michael Josef and Wege, Christian},
  title     = {Penicillin Detection by Tobacco Mosaic Virus-Assisted Colorimetric Biosensors},
  series = {Nanotheranostics},
  volume    = {2},
  journal   = {Nanotheranostics},
  number    = {2},
  publisher = {Ivyspring},
  address   = {Sydney},
  issn      = {2206-7418},
  doi       = {10.7150/ntno.22114},
  pages     = {184 -- 196},
  year      = {2018},
  abstract  = {The presentation of enzymes on viral scaffolds has beneficial effects such as an increased enzyme loading and a prolonged reusability in comparison to conventional immobilization platforms. Here, we used modified tobacco mosaic virus (TMV) nanorods as enzyme carriers in penicillin G detection for the first time. Penicillinase enzymes were conjugated with streptavidin and coupled to TMV rods by use of a bifunctional biotin-linker. Penicillinase-decorated TMV particles were characterized extensively in halochromic dye-based biosensing. Acidometric analyte detection was performed with bromcresol purple as pH indicator and spectrophotometry. The TMV-assisted sensors exhibited increased enzyme loading and strongly improved reusability, and higher analysis rates compared to layouts without viral adapters. They extended the half-life of the sensors from 4 - 6 days to 5 weeks and thus allowed an at least 8-fold longer use of the sensors. Using a commercial budget-priced penicillinase preparation, a detection limit of 100 µM penicillin was obtained. Initial experiments also indicate that the system may be transferred to label-free detection layouts.},
  language  = {en}
}
@incollection{KochPoghossianWegeetal.2018,
  author    = {Koch, Claudia and Poghossian, Arshak and Wege, Christina and Sch{\"o}ning, Michael Josef},
  title     = {TMV-Based Adapter Templates for Enhanced Enzyme Loading in Biosensor Applications},
  series = {Virus-Derived Nanoparticles for Advanced Technologies},
  booktitle = {Virus-Derived Nanoparticles for Advanced Technologies},
  editor    = {Wege, Christina},
  publisher = {Humana Press},
  address   = {New York, NY},
  isbn      = {978-1-4939-7808-3},
  doi       = {10.1007/978-1-4939-7808-3},
  pages     = {553 -- 568},
  year      = {2018},
  abstract  = {Nanotubular tobacco mosaic virus (TMV) particles and RNA-free lower-order coat protein (CP) aggregates have been employed as enzyme carriers in different diagnostic layouts and compared for their influence on biosensor performance. In the following, we describe a label-free electrochemical biosensor for improved glucose detection by use of TMV adapters and the enzyme glucose oxidase (GOD). A specific and efficient immobilization of streptavidin-conjugated GOD ([SA]-GOD) complexes on biotinylated TMV nanotubes or CP aggregates was achieved via bioaffinity binding. Glucose sensors with adsorptively immobilized [SA]-GOD, and with [SA]-GOD cross-linked with glutardialdehyde, respectively, were tested in parallel on the same sensor chip. Comparison of these sensors revealed that TMV adapters enhanced the amperometric glucose detection remarkably, conveying highest sensitivity, an extended linear detection range and fastest response times. These results underline a great potential of an integration of virus/biomolecule hybrids with electronic transducers for applications in biosensorics and biochips. Here, we describe the fabrication and use of amperometric sensor chips combining an array of circular Pt electrodes, their loading with GOD-modified TMV nanotubes (and other GOD immobilization methods), and the subsequent investigations of the sensor performance.},
  language  = {en}
}
@article{KramerHalamkovaPoghossianetal.2013,
  author    = {Kramer, Friederike and Halamkova, Lenka and Poghossian, Arshak and Sch{\"o}ning, Michael Josef and Katz, Evgeny and Halamek, Jan},
  title     = {Biocatalytic analysis of biomarkers for forensic identification of ethnicity between Caucasian and African American},
  series = {The analyst. August 2013},
  volume    = {Vol. 138},
  journal   = {The analyst. August 2013},
  publisher = {Royal Society of Chemistry},
  address   = {Cambridge},
  issn      = {1364-5528 (E-Journal); 0003-2654 (Print)},
  pages     = {6251 -- 6257},
  year      = {2013},
  language  = {en}
}
@article{KraemerPitaZhouetal.2009,
  author    = {Kr{\"a}mer, Melina and Pita, Marcos and Zhou, Jian and Ornatska, Maryna and Poghossian, Arshak and Sch{\"o}ning, Michael Josef and Katz, Evgeny},
  title     = {Coupling of Biocomputing Systems with Electronic Chips: Electronic Interface for Transduction of Biochemical Information},
  series = {Journal of Physical Chemistry C: Nanomaterials and Interfaces. 113 (2009), H. 6},
  journal   = {Journal of Physical Chemistry C: Nanomaterials and Interfaces. 113 (2009), H. 6},
  publisher = {American Cemical Society},
  address   = {Washington, DC},
  isbn      = {1932-7455},
  pages     = {2573 -- 2579},
  year      = {2009},
  language  = {en}
}
@article{LeinhosSchusserBaeckeretal.2014,
  author    = {Leinhos, Marcel and Schusser, Sebastian and B{\"a}cker, Matthias and Poghossian, Arshak and Sch{\"o}ning, Michael Josef},
  title     = {Micromachined multi-parameter sensor chip for the control of polymer-degradation medium},
  series = {Physica Status Solidi (A) : special issue on engineering and functional interfaces},
  volume    = {211},
  journal   = {Physica Status Solidi (A) : special issue on engineering and functional interfaces},
  number    = {6},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {1521-396X (E-Journal); 1862-6319 (E-Journal); 0031-8965 (Print); 1862-6300 (Print)},
  doi       = {10.1002/pssa.201330364},
  pages     = {1346 -- 1351},
  year      = {2014},
  abstract  = {It is well known that the degradation environment can strongly influence the biodegradability and kinetics of biodegradation processes of polymers. Therefore, besides the monitoring of the degradation process, it is also necessary to control the medium in which the degradation takes place. In this work, a micromachined multi-parameter sensor chip for the control of the polymer-degradation medium has been developed. The chip combines a capacitive field-effect pH sensor, a four-electrode electrolyte-conductivity sensor and a thin-film Pt-temperature sensor. The results of characterization of individual sensors are presented. In addition, the multi-parameter sensor chip together with an impedimetric polymer-degradation sensor was simultaneously characterized in degradation solutions with different pH and electrolyte conductivity. The obtained results demonstrate the feasibility of the multi-parameter sensor chip for the control of the polymer-degradation medium.},
  language  = {en}
}
@article{MolinnusBaeckerIkenetal.2015,
  author    = {Molinnus, Denise and B{\"a}cker, Matthias and Iken, Heiko and Poghossian, Arshak and Keusgen, Michael and Sch{\"o}ning, Michael Josef},
  title     = {Concept for a biomolecular logic chip with an integrated sensor and actuator function},
  series = {Physica status solidi (a)},
  volume    = {212},
  journal   = {Physica status solidi (a)},
  number    = {6},
  publisher = {Wiley},
  address   = {Weinheim},
  issn      = {1862-6319},
  doi       = {10.1002/pssa.201431913},
  pages     = {1382 -- 1388},
  year      = {2015},
  abstract  = {A concept for a new generation of an integrated multi-functional biosensor/actuator system is developed, which is based on biomolecular logic principles. Such a system is expected to be able to detect multiple biochemical input signals simultaneously and in real-time and convert them into electrical output signals with logical operations such as OR, AND, etc. The system can be designed as a closed-loop drug release device triggered by an enzyme logic gate, while the release of the drug induced by the actuator at the required dosage and timing will be controlled by an additional drug sensor. Thus, the system could help to make an accurate and specific diagnosis. The presented concept is exemplarily demonstrated by using an enzyme logic gate based on a glucose/glucose oxidase system, a temperature-responsive hydrogel mimicking the actuator function and an insulin (drug) sensor. In this work, the results of functional testing of individual amperometric glucose and insulin sensors as well as an impedimetric sensor for the detection of the hydrogel swelling/shrinking are presented.},
  language  = {en}
}
@article{MolinnusBaeckerSiegertetal.2015,
  author    = {Molinnus, Denise and B{\"a}cker, Matthias and Siegert, Petra and Willenberg, H. and Poghossian, Arshak and Keusgen, M. and Sch{\"o}ning, Michael Josef},
  title     = {Detection of Adrenaline Based on Substrate Recycling Amplification},
  series = {Procedia Engineering},
  volume    = {120},
  journal   = {Procedia Engineering},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1877-7058},
  doi       = {10.1016/j.proeng.2015.08.708},
  pages     = {540 -- 543},
  year      = {2015},
  abstract  = {An amperometric enzyme biosensor has been applied for the detection of adrenaline. The adrenaline biosensor has been prepared by modification of an oxygen electrode with the enzyme laccase that operates at a broad pH range between pH 3.5 to pH 8. The enzyme molecules were immobilized via cross-linking with glutaraldehyde. The sensitivity of the developed adrenaline biosensor in different pH buffer solutions has been studied.},
  language  = {en}
}
@article{MolinnusHardtKaeveretal.2018,
  author    = {Molinnus, Denise and Hardt, G. and K{\"a}ver, L. and Willenberg, H.S. and Kr{\"o}ger, J.-C. and Poghossian, Arshak and Keusgen, Michael and Sch{\"o}ning, Michael Josef},
  title     = {Chip-based biosensor for the detection of low adrenaline concentrations to support adrenal venous sampling},
  series = {Sensor and Actuators B: Chemical},
  volume    = {272},
  journal   = {Sensor and Actuators B: Chemical},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0925-4005},
  doi       = {10.1016/j.snb.2018.05.136},
  pages     = {21 -- 27},
  year      = {2018},
  abstract  = {A chip-based amperometric biosensor referring on using the bioelectrocatalytical amplification principle for the detection of low adrenaline concentrations is presented. The adrenaline biosensor has been prepared by modification of a platinum thin-film electrode with an enzyme membrane containing the pyrroloquinoline quinone-dependent glucose dehydrogenase and glutaraldehyde. Measuring conditions such as temperature, pH value, and glucose concentration have been optimized to achieve a high sensitivity and a low detection limit of about 1 nM adrenaline measured in phosphate buffer at neutral pH value. The response of the biosensor to different catecholamines has also been proven. Long-term stability of the adrenaline biosensor has been studied over 10 days. In addition, the biosensor has been successfully applied for adrenaline detection in human blood plasma for future biomedical applications. Furthermore, preliminary experiments have been carried to detect the adrenaline-concentration difference measured in peripheral blood and adrenal venous blood, representing the adrenal vein sampling procedure of a physician.},
  language  = {en}
}
@inproceedings{MolinnusHardtKaeveretal.2017,
  author    = {Molinnus, Denise and Hardt, Gabriel and K{\"a}ver, Larissa and Willenberg, Holger S. and Poghossian, Arshak and Keusgen, Michael and Sch{\"o}ning, Michael Josef},
  title     = {Detection of Adrenaline Based on Bioelectrocatalytical System to Support Tumor Diagnostic Technology},
  series = {MDPI Proceedings},
  booktitle = {MDPI Proceedings},
  doi       = {10.3390/proceedings1040506},
  pages     = {4 Seiten},
  year      = {2017},
  language  = {en}
}
@article{MolinnusHardtSiegertetal.2018,
  author    = {Molinnus, Denise and Hardt, Gabriel and Siegert, Petra and Willenberg, Holger S. and Poghossian, Arshak and Keusgen, Michael and Sch{\"o}ning, Michael Josef},
  title     = {Detection of Adrenaline in Blood Plasma as Biomarker for Adrenal Venous Sampling},
  series = {Electroanalysis},
  volume    = {30},
  journal   = {Electroanalysis},
  number    = {5},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {1521-4109},
  doi       = {10.1002/elan.201800026},
  pages     = {937 -- 942},
  year      = {2018},
  abstract  = {An amperometric bi-enzyme biosensor based on substrate recycling principle for the amplification of the sensor signal has been developed for the detection of adrenaline in blood. Adrenaline can be used as biomarker verifying successful adrenal venous sampling procedure. The adrenaline biosensor has been realized via modification of a galvanic oxygen sensor with a bi-enzyme membrane combining a genetically modified laccase and a pyrroloquinoline quinone-dependent glucose dehydrogenase. The measurement conditions such as pH value and temperature were optimized to enhance the sensor performance. A high sensitivity and a low detection limit of about 0.5-1 nM adrenaline have been achieved in phosphate buffer at pH 7.4, relevant for measurements in blood samples. The sensitivity of the biosensor to other catecholamines such as noradrenaline, dopamine and dobutamine has been studied. Finally, the sensor has been successfully applied for the detection of adrenaline in human blood plasma.},
  language  = {en}
}
@article{MolinnusIkenJohnenetal.2022,
  author    = {Molinnus, Denise and Iken, Heiko and Johnen, Anna Lynn and Richstein, Benjamin and Hellmich, Lena and Poghossian, Arshak and Knoch, Joachim and Sch{\"o}ning, Michael Josef},
  title     = {Miniaturized pH-Sensitive Field-Effect Capacitors with Ultrathin Ta₂O₅ Films Prepared by Atomic Layer Deposition},
  series = {physica status solidi (a) applications and materials science},
  volume    = {219},
  journal   = {physica status solidi (a) applications and materials science},
  number    = {8},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {1862-6319},
  doi       = {10.1002/pssa.202100660},
  pages     = {7 Seiten},
  year      = {2022},
  abstract  = {Miniaturized electrolyte-insulator-semiconductor capacitors (EISCAPs) with ultrathin gate insulators have been studied in terms of their pH-sensitive sensor characteristics: three different EISCAP systems consisting of Al-p-Si-Ta2O5(5 nm), Al-p-Si-Si3N4(1 or 2 nm)-Ta2O5 (5 nm), and Al-p-Si-SiO2(3.6 nm)-Ta2O5(5 nm) layer structures are characterized in buffer solution with different pH values by means of capacitance-voltage and constant capacitance method. The SiO2 and Si3N4 gate insulators are deposited by rapid thermal oxidation and rapid thermal nitridation, respectively, whereas the Ta2O5 film is prepared by atomic layer deposition. All EISCAP systems have a clear pH response, favoring the stacked gate insulators SiO2-Ta2O5 when considering the overall sensor characteristics, while the Si3N4(1 nm)-Ta2O5 stack delivers the largest accumulation capacitance (due to the lower equivalent oxide thickness) and a higher steepness in the slope of the capacitance-voltage curve among the studied stacked gate insulator systems.},
  language  = {en}
}
@article{MolinnusPoghossianKeusgenetal.2017,
  author    = {Molinnus, Denise and Poghossian, Arshak and Keusgen, Michael and Katz, Evgeny and Sch{\"o}ning, Michael Josef},
  title     = {Coupling of Biomolecular Logic Gates with Electronic Transducers: From Single Enzyme Logic Gates to Sense/Act/Treat Chips},
  series = {Electroanalysis},
  volume    = {29},
  journal   = {Electroanalysis},
  number    = {8},
  publisher = {Wiley},
  address   = {Weinheim},
  issn      = {1521-4109},
  doi       = {10.1002/elan.201700208},
  pages     = {1840 -- 1849},
  year      = {2017},
  abstract  = {The integration of biomolecular logic principles with electronic transducers allows designing novel digital biosensors with direct electrical output, logically triggered drug-release, and closed-loop sense/act/treat systems. This opens new opportunities for advanced personalized medicine in the context of theranostics. In the present work, we will discuss selected examples of recent developments in the field of interfacing enzyme logic gates with electrodes and semiconductor field-effect devices. Special attention is given to an enzyme OR/Reset logic gate based on a capacitive field-effect electrolyte-insulator-semiconductor sensor modified with a multi-enzyme membrane. Further examples are a digital adrenaline biosensor based on an AND logic gate with binary YES/NO output and an integrated closed-loop sense/act/treat system comprising an amperometric glucose sensor, a hydrogel actuator, and an insulin (drug) sensor.},
  language  = {en}
}
@article{MolinnusSorichBartzetal.2016,
  author    = {Molinnus, Denise and Sorich, Maren and Bartz, Alexander and Siegert, Petra and Willenberg, Holger S. and Lisdat, Fred and Poghossian, Arshak and Keusgen, Michael and Sch{\"o}ning, Michael Josef},
  title     = {Towards an adrenaline biosensor based on substrate recycling amplification in combination with an enzyme logic gate},
  series = {Sensors and Actuators B: Chemical},
  volume    = {237},
  journal   = {Sensors and Actuators B: Chemical},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0925-4005},
  doi       = {10.1016/j.snb.2016.06.064},
  pages     = {190 -- 195},
  year      = {2016},
  abstract  = {An amperometric biosensor using a substrate recycling principle was realized for the detection of low adrenaline concentrations (1 nM) by measurements in phosphate buffer and Ringer's solution at pH 6.5 and pH 7.4, respectively. In proof-of-concept experiments, a Boolean logic-gate principle has been applied to develop a digital adrenaline biosensor based on an enzyme AND logic gate. The obtained results demonstrate that the developed digital biosensor is capable for a rapid qualitative determination of the presence/absence of adrenaline in a YES/NO statement. Such digital biosensor could be used in clinical diagnostics for the control of a correct insertion of a catheter in the adrenal veins during adrenal venous-sampling procedure.},
  language  = {en}
}
@article{MoseleyHalamekKrameretal.2014,
  author    = {Moseley, Fiona and Halamek, Jan and Kramer, Friederike and Poghossian, Arshak and Sch{\"o}ning, Michael Josef and Katz, Evgeny},
  title     = {An enzyme-based reversible CNOT logic gate realized in a flow system},
  series = {Analyst},
  volume    = {139},
  journal   = {Analyst},
  number    = {8},
  publisher = {Royal Society of Chemistry},
  address   = {Cambridge},
  issn      = {1364-5528 (E-Journal) ; 0003-2654 (Print)},
  doi       = {10.1039/C4AN00133H},
  pages     = {1839 -- 1842},
  year      = {2014},
  abstract  = {An enzyme system organized in a flow device was used to mimic a reversible Controlled NOT (CNOT) gate with two input and two output signals. Reversible conversion of NAD⁺ and NADH cofactors was used to perform a XOR logic operation, while biocatalytic hydrolysis of p-nitrophenyl phosphate resulted in an Identity operation working in parallel. The first biomolecular realization of a CNOT gate is promising for integration into complex biomolecular networks and future biosensor/biomedical applications.},
  language  = {en}
}
@article{MourzinaMaiPoghossianetal.2003,
  author    = {Mourzina, Y. and Mai, T. and Poghossian, Arshak and Ermolenko, Y. and Yoshinobu, T. and Vlasov, Y. and Iwasaki, H. and Sch{\"o}ning, Michael Josef},
  title     = {K+-selective field-effect sensors as transducers for bioelectronic applications},
  series = {Electrochimica Acta. 48 (2003), H. 20-22},
  journal   = {Electrochimica Acta. 48 (2003), H. 20-22},
  isbn      = {0013-4686},
  pages     = {3333 -- 3339},
  year      = {2003},
  language  = {en}
}
@article{NaetherAugerPoghossianetal.2004,
  author    = {N{\"a}ther, Niko and Auger, V. and Poghossian, Arshak and Koudelka-Hep, M. and Sch{\"o}ning, Michael Josef},
  title     = {A miniaturized flow-through cell in SU-8 technique for EIS sensors},
  series = {Biomedizinische Technik. 49 (2004), H. 2},
  journal   = {Biomedizinische Technik. 49 (2004), H. 2},
  isbn      = {0932-4666},
  pages     = {994 -- 995},
  year      = {2004},
  language  = {en}
}
@inproceedings{NaetherPoghossianPlatenetal.2006,
  author    = {N{\"a}ther, Niko and Poghossian, Arshak and Platen, J. and Yoshinobu, T. and Koudelka-Hep, M. and Sch{\"o}ning, Michael Josef},
  title     = {Multi-parameter sensing of both physical and (bio-)chemical quantities using the same transducer principle},
  series = {Biochemical sensing utilisation of micro- and nanotechnologies : Warsaw, [23rd - 26th] November 2005 / ed. by M. Mascini ...},
  booktitle = {Biochemical sensing utilisation of micro- and nanotechnologies : Warsaw, [23rd - 26th] November 2005 / ed. by M. Mascini ...},
  address   = {Warsaw},
  pages     = {172 -- 181},
  year      = {2006},
  language  = {en}
}
@article{NaetherRolkaPoghossianetal.2005,
  author    = {N{\"a}ther, Niko and Rolka, David and Poghossian, Arshak and Koudelka-Hep, M. and Sch{\"o}ning, Michael Josef},
  title     = {Two microcell flow-injection analysis (FIA) platforms for capacitive silicon-based field-effect sensors},
  series = {Electrochimica Acta. 51 (2005), H. 5},
  journal   = {Electrochimica Acta. 51 (2005), H. 5},
  isbn      = {0013-4686},
  doi       = {10.1016/j.electacta.2005.04.066},
  pages     = {924 -- 929},
  year      = {2005},
  language  = {en}
}
@article{PitaKraemerZouhetal.2008,
  author    = {Pita, Marcos and Kr{\"a}mer, Melina and Zouh, Jian and Poghossian, Arshak and Sch{\"o}ning, Michael Josef and Fernandez, Victor M. and Katz, Evgeny},
  title     = {Optoelectronic Properties of Nanostructured Ensembles Controlled by Biomolecular Logic Systems},
  series = {ACS Nano. 10 (2008), H. 2},
  journal   = {ACS Nano. 10 (2008), H. 2},
  isbn      = {1936-086X},
  pages     = {2160 -- 2166},
  year      = {2008},
  language  = {en}
}
@inproceedings{PlatenPoghossianSchoening2006,
  author    = {Platen, Johannes and Poghossian, Arshak and Sch{\"o}ning, Michael Josef},
  title     = {Microstructured Nanostructures - nanostructuring by means of conventional photolithography and layer-expansion technique},
  url       = {http://nbn-resolving.de/urn:nbn:de:hbz:a96-opus-1477},
  year      = {2006},
  abstract  = {A new and simple method for nanostructuring using conventional photolithography and layer expansion or pattern-size reduction technique is presented, which can further be applied for the fabrication of different nanostructures and nano-devices. The method is based on the conversion of a photolithographically patterned metal layer to a metal-oxide mask with improved pattern-size resolution using thermal oxidation. With this technique, the pattern size can be scaled down to several nanometer dimensions. The proposed method is experimentally demonstrated by preparing nanostructures with different configurations and layouts, like circles, rectangles, trapezoids, "fluidic-channel"-, "cantilever"- and meander-type structures.},
  subject      = {Biosensor},
  language  = {en}
}
@article{PoghossianAbouzarAmbergeretal.2007,
  author    = {Poghossian, Arshak and Abouzar, Maryam H. and Amberger, F. and Mayer, D. and Han, Y. and Ingebrandt, S. and Offenh{\"a}usser, A. and Sch{\"o}ning, Michael Josef},
  title     = {Field-effect sensors with charged macromolecules: Characterisation by capacitance-voltage, constant-capacitance, impedance spectroscopy and atomic-force microscopy methods},
  series = {Biosensors and Bioelectronics. 22 (2007), H. 9-10},
  journal   = {Biosensors and Bioelectronics. 22 (2007), H. 9-10},
  isbn      = {0956-5663},
  pages     = {2100 -- 2107},
  year      = {2007},
  language  = {en}
}
@article{PoghossianAbouzarChristiaensetal.2007,
  author    = {Poghossian, Arshak and Abouzar, Maryam H. and Christiaens, P. and Williams, O. A. and Haenen, K. and Wagner, P. and Sch{\"o}ning, Michael Josef},
  title     = {Nanocrystalline diamond-based field-effect (bio-)chemical sensor},
  series = {8. Dresdner Sensor-Symposium : Sensoren f{\"u}r Umwelt, Klima und Sicherheit, Biosensoren und Biosysteme, Sensoren und Sensorsysteme f{\"u}r die Prozesstechnik, Trends in der Sensortechnik, Materialentwicklung f{\"u}r die Sensorik; 8. Dresdner Sensor-Symposium, 10. - 12. Dezember 2007, Dresden / Gerald Gerlach ... (Hg.)},
  journal   = {8. Dresdner Sensor-Symposium : Sensoren f{\"u}r Umwelt, Klima und Sicherheit, Biosensoren und Biosysteme, Sensoren und Sensorsysteme f{\"u}r die Prozesstechnik, Trends in der Sensortechnik, Materialentwicklung f{\"u}r die Sensorik; 8. Dresdner Sensor-Symposium, 10. - 12. Dezember 2007, Dresden / Gerald Gerlach ... (Hg.)},
  publisher = {TUDpress, Verl. der Wissenschaften},
  address   = {Dresden},
  isbn      = {978-3-940046-45-1},
  pages     = {191 -- 194},
  year      = {2007},
  language  = {en}
}
@article{PoghossianAbouzarChristiaensetal.2008,
  author    = {Poghossian, Arshak and Abouzar, Maryam H. and Christiaens, P. and Williams, O. A. and Haenen, K. and Wagner, Patrick and Sch{\"o}ning, Michael Josef},
  title     = {Sensing charged macromolecules with nanocrystalline diamond-based field-effect capacitive sensors},
  series = {Journal of Contemporary Physics. 43 (2008), H. 2},
  journal   = {Journal of Contemporary Physics. 43 (2008), H. 2},
  isbn      = {1934-9378},
  pages     = {77 -- 81},
  year      = {2008},
  language  = {en}
}
@article{PoghossianAbouzarRazavietal.2009,
  author    = {Poghossian, Arshak and Abouzar, Maryam H. and Razavi, A. and B{\"a}cker, Matthias and Bijnens, N. and Williams, O. A. and Haenen, K. and Moritz, W. and Wagner, P. and Sch{\"o}ning, Michael Josef},
  title     = {Nanocrystalline-diamond thin films with high pH and penicillin sensitivity prepared on a capacitive Si-SiO2 structure},
  series = {Electrochimica Acta. 54 (2009), H. 25},
  journal   = {Electrochimica Acta. 54 (2009), H. 25},
  isbn      = {0013-4686},
  pages     = {5981 -- 5985},
  year      = {2009},
  language  = {en}
}
@article{PoghossianAbouzarSakkarietal.2006,
  author    = {Poghossian, Arshak and Abouzar, Maryam H. and Sakkari, M. and Kassab, T. and Han, Y. and Ingebrandt, S. and Offenh{\"a}usser, A. and Sch{\"o}ning, Michael Josef},
  title     = {Field-effect sensors for monitoring the layer-by-layer adsorption of charged macromolecules},
  series = {Sensors and Actuators B: Chemical. 118 (2006), H. 1-2},
  journal   = {Sensors and Actuators B: Chemical. 118 (2006), H. 1-2},
  isbn      = {0925-4005},
  pages     = {163 -- 170},
  year      = {2006},
  language  = {en}
}
@article{PoghossianAbouzarSchoening2008,
  author    = {Poghossian, Arshak and Abouzar, Maryam H. and Sch{\"o}ning, Michael Josef},
  title     = {Capacitance-voltage and impedance characteristics of field-effect EIS sensors functionalised with polyelectrolyte multilayers},
  series = {IRBM. 29 (2008), H. 2-3},
  journal   = {IRBM. 29 (2008), H. 2-3},
  isbn      = {1959-0318},
  pages     = {149 -- 154},
  year      = {2008},
  language  = {en}
}
@inproceedings{PoghossianAbouzarSchoening2012,
  author    = {Poghossian, Arshak and Abouzar, Maryam H. and Sch{\"o}ning, Michael Josef},
  title     = {(Bio-­)chemical sensor array based on nanoplate SOI capacitors},
  series = {Nanoscale Science and Technology (NS\&T´12) : Proceedings Book Humboldt Kolleg ; Tunisia, 17-19 March, 2012},
  booktitle = {Nanoscale Science and Technology (NS\&T´12) : Proceedings Book Humboldt Kolleg ; Tunisia, 17-19 March, 2012},
  editor    = {Abdelghani, Adnane and Sch{\"o}ning, Michael Josef},
  pages     = {31 -- 31},
  year      = {2012},
  language  = {en}
}
@article{PoghossianBaadeEmonsetal.2001,
  author    = {Poghossian, Arshak and Baade, A. and Emons, H. and Sch{\"o}ning, Michael Josef},
  title     = {Application of ISFET for pH measurements in rain droplets},
  series = {Sensors and Actuators B. 76 (2001), H. 1-3},
  journal   = {Sensors and Actuators B. 76 (2001), H. 1-3},
  isbn      = {0925-4005},
  pages     = {634 -- 638},
  year      = {2001},
  language  = {en}
}
@article{PoghossianBerndsenSchultzeetal.2001,
  author    = {Poghossian, Arshak and Berndsen, L. and Schultze, J. W. and L{\"u}th, H. and Sch{\"o}ning, Michael Josef},
  title     = {„High order" hybrid sensor module based on an identical transducer principle},
  series = {Chemical and biological sensors and analytical methods : proceedings of the international symposium / Sensor, Physical Electrochemistry, and Organic and Biological Electrochemistry Divisions. Ed.: M. Butler},
  journal   = {Chemical and biological sensors and analytical methods : proceedings of the international symposium / Sensor, Physical Electrochemistry, and Organic and Biological Electrochemistry Divisions. Ed.: M. Butler},
  publisher = {Electrochemical Society},
  address   = {Pennington, NJ},
  isbn      = {1-56677-351-2},
  pages     = {143 -- 152},
  year      = {2001},
  language  = {en}
}
@article{PoghossianBerndsenSchoening2002,
  author    = {Poghossian, Arshak and Berndsen, L. and Sch{\"o}ning, Michael Josef},
  title     = {Chemical sensor as a physical sensor: ISFET-based flowvelocity, flow-direction and diffusion-coefficient sensor},
  series = {Book of abstracts / ed. by J. Saneistr.},
  journal   = {Book of abstracts / ed. by J. Saneistr.},
  publisher = {Czech Technical University, Faculty of Electrical Engineering, Department of Measurement},
  address   = {Prague},
  isbn      = {80-01-02576-4},
  pages     = {649 -- 652},
  year      = {2002},
  language  = {en}
}
@article{PoghossianBerndsenLuethetal.2001,
  author    = {Poghossian, Arshak and Berndsen, Lars and L{\"u}th, Hans and Sch{\"o}ning, Michael Josef},
  title     = {Novel concepts for flow-rate and flow-direction determination by means of pH-sensitive ISFETs},
  series = {Proceedings of SPIE. 4560 (2001)},
  journal   = {Proceedings of SPIE. 4560 (2001)},
  pages     = {19 -- 27},
  year      = {2001},
  language  = {en}
}
@article{PoghossianBerndsenSchoening2003,
  author    = {Poghossian, Arshak and Berndsen, Lars and Sch{\"o}ning, Michael Josef},
  title     = {Chemical sensor as physical sensor: ISFET-based flowvelocity, flow-direction and diffusion-coefficient sensor},
  series = {Sensors and Actuators B. 95 (2003), H. 1-3},
  journal   = {Sensors and Actuators B. 95 (2003), H. 1-3},
  isbn      = {0925-4005},
  pages     = {384 -- 390},
  year      = {2003},
  language  = {en}
}
@inproceedings{PoghossianBronderSchejaetal.2016,
  author    = {Poghossian, Arshak and Bronder, Thomas and Scheja, S. and Wu, Chunsheng and Metzger-Boddien, C. and Keusgen, M. and Sch{\"o}ning, Michael Josef},
  title     = {Label-free Electrostatic Detection of DNA Amplification by PCR Using Capacitive Field-effect Devices},
  series = {Procedia Engineering},
  volume    = {Vol. 168},
  booktitle = {Procedia Engineering},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1877-7058},
  doi       = {10.1016/j.proeng.2016.11.512},
  pages     = {514 -- 517},
  year      = {2016},
  abstract  = {A capacitive field-effect EIS (electrolyte-insulator-semiconductor) sensor modified with a positively charged weak polyelectrolyte of poly(allylamine hydrochloride) (PAH)/single-stranded probe DNA (ssDNA) bilayer has been used for a label-free electrostatic detection of pathogen-specific DNA amplification via polymerase chain reaction (PCR). The sensor is able to distinguish between positive and negative PCR solutions, to detect the existence of target DNA amplicons in PCR samples and thus, can be used as tool for a quick verification of DNA amplification and the successful PCR process.},
  language  = {en}
}
@inproceedings{PoghossianBronderWuetal.2015,
  author    = {Poghossian, Arshak and Bronder, Thomas and Wu, Chunsheng and Sch{\"o}ning, Michael Josef},
  title     = {Label-free sensing of biomolecules by their intrinsic molecular charge using field-effect devices},
  series = {Semiconductor Micro- and Nanoelectonics : Proceedings of the tenth international conference, Yerevan, Armenia, September 11-13},
  booktitle = {Semiconductor Micro- and Nanoelectonics : Proceedings of the tenth international conference, Yerevan, Armenia, September 11-13},
  isbn      = {978-5-8084-1991-9},
  pages     = {61 -- 63},
  year      = {2015},
  language  = {en}
}
@article{PoghossianBaeckerMayeretal.2015,
  author    = {Poghossian, Arshak and B{\"a}cker, Matthias and Mayer, Dirk and Sch{\"o}ning, Michael Josef},
  title     = {Gating capacitive field-effect sensors by the charge of nanoparticle/molecule hybrids},
  series = {Nanoscale},
  journal   = {Nanoscale},
  publisher = {Royal Society of Chemistry (RSC)},
  address   = {Cambridge},
  issn      = {2040-3372 (E-Journal); 2040-3364 (Print)},
  doi       = {10.1039/C4NR05987E},
  pages     = {1023 -- 1031},
  year      = {2015},
  language  = {en}
}
@article{PoghossianCherstvyIngebrandtetal.2005,
  author    = {Poghossian, Arshak and Cherstvy, A. and Ingebrandt, S. and Offenh{\"a}usser, A. and Sch{\"o}ning, Michael Josef},
  title     = {Possibilities and limitations of label-free detection of DNA hybridization with field-effect-based devices},
  series = {Sensors and Actuators B. 111-112 (2005)},
  journal   = {Sensors and Actuators B. 111-112 (2005)},
  isbn      = {0925-4005},
  pages     = {470 -- 480},
  year      = {2005},
  language  = {en}
}
@article{PoghossianCherstvySchoening2004,
  author    = {Poghossian, Arshak and Cherstvy, A. and Sch{\"o}ning, Michael Josef},
  title     = {Possibilities and limitations of label-free detection of DNA hybridization with field-effect based devices},
  series = {Digest of technical papers : September 12 - 15, 2004, Rome, Italy, Pontificia Universitas Sancto Thoma Aquinate in Urbe / [conference chairperson: C. Di Natale].},
  journal   = {Digest of technical papers : September 12 - 15, 2004, Rome, Italy, Pontificia Universitas Sancto Thoma Aquinate in Urbe / [conference chairperson: C. Di Natale].},
  address   = {Roma},
  isbn      = {88-7621-282-5},
  pages     = {173 -- 176},
  year      = {2004},
  language  = {en}
}
@article{PoghossianGeisslerSchoening2019,
  author    = {Poghossian, Arshak and Geissler, Hanno and Sch{\"o}ning, Michael Josef},
  title     = {Rapid methods and sensors for milk quality monitoring and spoilage detection},
  series = {Biosensors and Bioelectronics},
  volume    = {140},
  journal   = {Biosensors and Bioelectronics},
  number    = {Article 111272},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0956-5663},
  doi       = {10.1016/j.bios.2019.04.040},
  year      = {2019},
  language  = {en}
}
@article{PoghossianIngebrandtAbouzaretal.2007,
  author    = {Poghossian, Arshak and Ingebrandt, S. and Abouzar, Maryam H. and Sch{\"o}ning, Michael Josef},
  title     = {Label-free detection of charged macromolecules by using a field-effect-based sensor platform: Experiments and possible mechanisms of signal generation},
  series = {Applied Physics A: Materials Science \& Processing. 87 (2007), H. 3},
  journal   = {Applied Physics A: Materials Science \& Processing. 87 (2007), H. 3},
  isbn      = {0947-8396},
  pages     = {517 -- 524},
  year      = {2007},
  language  = {en}
}