@article{HaegerJolmesOyenetal.2024,
  author    = {Haeger, Gerrit and Jolmes, Tristan and Oyen, Sven and Jaeger, Karl-Erich and Bongaerts, Johannes and Sch{\"o}rken, Ulrich and Siegert, Petra},
  title     = {Novel recombinant aminoacylase from Paraburkholderia monticola capable of N-acyl-amino acid synthesis},
  series = {Applied Microbiology and Biotechnology},
  journal   = {Applied Microbiology and Biotechnology},
  number    = {108},
  publisher = {Springer},
  address   = {Berlin},
  issn      = {1432-0614},
  doi       = {10.1007/s00253-023-12868-8},
  pages     = {14 Seiten},
  year      = {2024},
  abstract  = {N-Acyl-amino acids can act as mild biobased surfactants, which are used, e.g., in baby shampoos. However, their chemical synthesis needs acyl chlorides and does not meet sustainability criteria. Thus, the identification of biocatalysts to develop greener synthesis routes is desirable. We describe a novel aminoacylase from Paraburkholderia monticola DSM 100849 (PmAcy) which was identified, cloned, and evaluated for its N-acyl-amino acid synthesis potential. Soluble protein was obtained by expression in lactose autoinduction medium and co-expression of molecular chaperones GroEL/S. Strep-tag affinity purification enriched the enzyme 16-fold and yielded 15 mg pure enzyme from 100 mL of culture. Biochemical characterization revealed that PmAcy possesses beneficial traits for industrial application like high temperature and pH-stability. A heat activation of PmAcy was observed upon incubation at temperatures up to 80 °C. Hydrolytic activity of PmAcy was detected with several N-acyl-amino acids as substrates and exhibited the highest conversion rate of 773 U/mg with N-lauroyl-L-alanine at 75 °C. The enzyme preferred long-chain acyl-amino-acids and displayed hardly any activity with acetyl-amino acids. PmAcy was also capable of N-acyl-amino acid synthesis with good conversion rates. The best synthesis results were obtained with the cationic L-amino acids L-arginine and L-lysine as well as with L-leucine and L-phenylalanine. Exemplarily, L-phenylalanine was acylated with fatty acids of chain lengths from C8 to C18 with conversion rates of up to 75\%. N-lauroyl-L-phenylalanine was purified by precipitation, and the structure of the reaction product was verified by LC-MS and NMR.},
  language  = {en}
}
@article{LuftLuftArntz2023,
  author    = {Luft, Angela and Luft, Nils and Arntz, Kristian},
  title     = {A basic description logic for service-oriented architecture in factory planning and operational control in the age of industry 4.0},
  series = {Applied Sciences},
  volume    = {2023},
  journal   = {Applied Sciences},
  number    = {13},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {2076-3417},
  doi       = {10.3390/app13137610},
  pages     = {23 Seiten},
  year      = {2023},
  abstract  = {Manufacturing companies across multiple industries face an increasingly dynamic and unpredictable environment. This development can be seen on both the market and supply side. To respond to these challenges, manufacturing companies must implement smart manufacturing systems and become more flexible and agile. The flexibility in operational planning regarding the scheduling and sequencing of customer orders needs to be increased and new structures must be implemented in manufacturing systems' fundamental design as they constitute much of the operational flexibility available. To this end, smart and more flexible solutions for production planning and control (PPC) are developed. However, scheduling or sequencing is often only considered isolated in a predefined stable environment. Moreover, their orientation on the fundamental logic of the existing IT solutions and their applicability in a dynamic environment is limited. This paper presents a conceptual model for a task-based description logic that can be applied to factory planning, technology planning, and operational control. By using service-oriented architectures, the goal is to generate smart manufacturing systems. The logic is designed to allow for easy and automated maintenance. It is compatible with the existing resource and process allocation logic across operational and strategic factory and production planning.},
  language  = {en}
}
@article{DobbertinEilmannBleuleretal.2010,
  author    = {Dobbertin, Matthias and Eilmann, Britta and Bleuler, Peter and Giuggiola, Arnaud and Graf Pannatier, Elisabeth and Landolt, Werner and Schleppi, Patrick and Rigling, Andreas},
  title     = {Effect of irrigation on needle morphology, shoot and stem growth in a drought-exposed Pinus sylvestris forest},
  series = {Tree Physiology},
  volume    = {30},
  journal   = {Tree Physiology},
  number    = {3},
  publisher = {Oxford University Press},
  address   = {Oxford},
  issn      = {1758-4469 (Online)},
  doi       = {10.1093/treephys/tpp123},
  pages     = {346 -- 360},
  year      = {2010},
  abstract  = {In Valais, Switzerland, Scots pines (Pinus sylvestris L.) are declining, mainly following drought. To assess the impact of drought on tree growth and survival, an irrigation experiment was initiated in 2003 in a mature pine forest, approximately doubling the annual precipitation. Tree crown transparency (lack of foliage) and leaf area index (LAI) were annually assessed. Seven irrigated and six control trees were felled in 2006, and needles, stem discs and branches were taken for growth analysis. Irrigation in 2004 and 2005, both with below-average precipitation, increased needle size, area and mass, stem growth and, with a 1-year delay, shoot length. This led to a relative decrease in tree crown transparency (-14\%) and to an increase in stand LAI (+20\%). Irrigation increased needle length by 70\%, shoot length by 100\% and ring width by 120\%, regardless of crown transparency. Crown transparency correlated positively with mean needle size, shoot length and ring width and negatively with specific leaf area. Trees with high crown transparency (low growth, short needles) experienced similar increases in needle mass and growth with irrigation than trees with low transparency (high growth, long needles), indicating that seemingly declining trees were able to 'recover' when water supply became sufficient. A simple drought index before and during the irrigation explained most of the variation found in the parameters for both irrigated and control trees.},
  language  = {en}
}
@article{Huening2019,
  author    = {H{\"u}ning, Felix},
  title     = {Nachr{\"u}stm{\"o}glichkeiten von Dieselfahrzeugen aus technischer Sicht},
  series = {Zeitschrift f{\"u}r Verkehrsrecht : NZV},
  journal   = {Zeitschrift f{\"u}r Verkehrsrecht : NZV},
  number    = {1},
  publisher = {C.H.Beck},
  pages     = {27 -- 32},
  year      = {2019},
  language  = {de}
}
@article{TixMollKrafftetal.2024,
  author    = {Tix, Julian and Moll, Fabian and Krafft, Simone and Betsch, Matthias and Tippk{\"o}tter, Nils},
  title     = {Hydrogen production from enzymatic pretreated organic waste with thermotoga neapolitana},
  series = {Energies},
  volume    = {17},
  journal   = {Energies},
  number    = {12},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {1996-1073},
  doi       = {10.3390/en17122938},
  pages     = {20 Seiten},
  year      = {2024},
  abstract  = {Biomass from various types of organic waste was tested for possible use in hydrogen production. The composition consisted of lignified samples, green waste, and kitchen scraps such as fruit and vegetable peels and leftover food. For this purpose, the enzymatic pretreatment of organic waste with a combination of five different hydrolytic enzymes (cellulase, amylase, glucoamylase, pectinase and xylase) was investigated to determine its ability to produce hydrogen (H2) with the hydrolyzate produced here. In course, the anaerobic rod-shaped bacterium T. neapolitana was used for H2 production. First, the enzymes were investigated using different substrates in preliminary experiments. Subsequently, hydrolyses were carried out using different types of organic waste. In the hydrolysis carried out here for 48 h, an increase in glucose concentration of 481\% was measured for waste loads containing starch, corresponding to a glucose concentration at the end of hydrolysis of 7.5 g·L-1. In the subsequent set fermentation in serum bottles, a H2 yield of 1.26 mmol H2 was obtained in the overhead space when Terrific Broth Medium with glucose and yeast extract (TBGY medium) was used. When hydrolyzed organic waste was used, even a H2 yield of 1.37 mmol could be achieved in the overhead space. In addition, a dedicated reactor system for the anaerobic fermentation of T. neapolitana to produce H2 was developed. The bioreactor developed here can ferment anaerobically with a very low loss of produced gas. Here, after 24 h, a hydrogen concentration of 83\% could be measured in the overhead space.},
  language  = {en}
}
@article{HeinrichsUttingFrauenrathetal.2009,
  author    = {Heinrichs, Uwe and Utting, Jane F. and Frauenrath, Tobias and Hezel, Fabian and Krombach, Gabriele A. and Hodenius, Michael A. J. and Kozerke, Sebastian and Niendorf, Thoralf},
  title     = {Myocardial T2 mapping free of distortion using susceptibility-weighted fast spin-echo imaging: A feasibility study at 1.5 T and 3.0 T},
  series = {Magnetic Resonance in Medicine},
  volume    = {62},
  journal   = {Magnetic Resonance in Medicine},
  number    = {3},
  publisher = {Wiley-Liss},
  address   = {New York},
  issn      = {1522-2594},
  doi       = {10.1002/mrm.22054},
  pages     = {822 -- 828},
  year      = {2009},
  abstract  = {This study demonstrates the feasibility of applying free-breathing, cardiac-gated, susceptibility-weighted fast spin-echo imaging together with black blood preparation and navigator-gated respiratory motion compensation for anatomically accurate T₂ mapping of the heart. First, T₂ maps are presented for oil phantoms without and with respiratory motion emulation (T₂ = (22.1 ± 1.7) ms at 1.5 T and T₂ = (22.65 ± 0.89) ms at 3.0 T). T₂ relaxometry of a ferrofluid revealed relaxivities of R2 = (477.9 ± 17) mM⁻¹s⁻¹ and R2 = (449.6 ± 13) mM⁻¹s⁻¹ for UFLARE and multiecho gradient-echo imaging at 1.5 T. For inferoseptal myocardial regions mean T₂ values of 29.9 ± 6.6 ms (1.5 T) and 22.3 ± 4.8 ms (3.0 T) were estimated. For posterior myocardial areas close to the vena cava T₂-values of 24.0 ± 6.4 ms (1.5 T) and 15.4 ± 1.8 ms (3.0 T) were observed. The merits and limitations of the proposed approach are discussed and its implications for cardiac and vascular T₂-mapping are considered.},
  language  = {en}
}
@article{Fabo2010,
  author    = {Fabo, Sabine},
  title     = {Sisyphus wird Steiff},
  series = {Pr{\"a}dikat spießig (Boxhorn ; 21)},
  volume    = {2010},
  journal   = {Pr{\"a}dikat spießig (Boxhorn ; 21)},
  editor    = {Mohr, Klaus},
  publisher = {FH Aachen, Fachbereich Gestaltung},
  address   = {Aachen},
  issn      = {1864-2535},
  pages     = {58 -- 61},
  year      = {2010},
  abstract  = {Eine Reise durch die fremde Welt eines Kaufhaus-Schaufensters. Pl{\"u}schtiere mit eingebauter Bewegungstechnik - knuffig oder nur eine Ausformulierung des Ernst des Lebens?},
  language  = {de}
}
@article{WolfAltgen2013,
  author    = {Wolf, Martin R. and Altgen, Jannik},
  title     = {IT Service Management in der Region Aachen : White Paper},
  pages     = {1 -- 13},
  year      = {2013},
  language  = {de}
}
@article{AnikTuelbentci1974,
  author    = {Anik, Sabri and Tuelbentci, K.},
  title     = {Lichtbogenschweißen : Untersuchung der Schweißschlacke und der Wirkungen auf das Entfernen der Schlacke ; Teil 3},
  series = {Technische Rundschau : TR ; das Schweizer Industrie-Magazin},
  volume    = {66},
  journal   = {Technische Rundschau : TR ; das Schweizer Industrie-Magazin},
  number    = {2},
  publisher = {Medtrix Group},
  address   = {Basel},
  issn      = {0040-148X},
  pages     = {43 -- 47},
  year      = {1974},
  language  = {de}
}
@article{FerreinMeyer2012,
  author    = {Ferrein, Alexander and Meyer, Thomas},
  title     = {A Brief Overview of Artificial Intelligence in South Africa},
  series = {AI Magazine},
  volume    = {33},
  journal   = {AI Magazine},
  number    = {1},
  publisher = {AAAI},
  address   = {Menlo Park},
  issn      = {0738-4602},
  doi       = {10.1609/aimag.v33i1.2357},
  pages     = {99 -- 101},
  year      = {2012},
  abstract  = {South Africa in recent years is the establishment of a number of research hubs involved in AI activities ranging from mobile robotics and computational intelligence, to knowledge representation and reasoning, and human language technologies. In this survey we take the reader through a quick tour of the research being conducted at these hubs, and touch on an initiative to maintain and extend the current level of interest in AI research in the country.},
  language  = {en}
}