@article{PinkenburgSchiffelsSelmer2016, author = {Pinkenburg, Olaf and Schiffels, Johannes and Selmer, Thorsten}, title = {Das CoLibry-Konzept - ein Werkzeugkasten f{\"u}r die Synthetische Biologie: Bioproduktion}, series = {BIOspektrum}, volume = {22}, journal = {BIOspektrum}, number = {6}, publisher = {Springer}, address = {Berlin}, doi = {10.1007/s12268-016-0734-8}, pages = {593 -- 595}, year = {2016}, abstract = {Regardless of size or destination, synthetic biology starts with com-parably small information units, which need to be combined and properly arranged in order to achieve a certain goal. This may be the de novo synthesis of individual genes from oligonucleotides, a shuffling of protein domains in order to create novel biocatalysts, the assembly of multiple enzyme encoding genes in metabolic pathway design, or strain development at the production stage. The CoLibry concept has been designed in order to close the gap between recombinant production of individual genes and genome editing.}, language = {de} } @inproceedings{FredebeulKrein2016, author = {Fredebeul-Krein, Markus}, title = {Towards trade facilitation via regulatory convergence: An analysis of the TTIP chapter on Electronic Communications}, series = {Regional ITS Conference of the International Telecommunications Society. Cambridge, United Kingdom, 7-9 September 2016}, booktitle = {Regional ITS Conference of the International Telecommunications Society. Cambridge, United Kingdom, 7-9 September 2016}, pages = {29 Seiten}, year = {2016}, abstract = {To give the exchange of goods and services between the European Union (EU) and the United States (U.S.) new momentum the two parties are currently negotiating the transatlantic free trade agreement Transatlantic Trade and Investment Partnership (TTIP). The aim is to create the largest free trade area in the world. The agreement, once entered into force, will oblige EU countries and the U.S. to further liberalize their markets. The negotiations on TTIP include a chapter on Electronic Communications/ Telecommunications. The challenge therein will be securing commitments for market access to Electronic Communications services. At the same time, these commitments must reflect the legitimate need for consumer protection issues. The need to reduce Electronic Communications-related non-tariff barriers to trade between the Parties is due to the fact that these markets are heavily regulated. Without transnational rules as to regulations national governments can abuse these regulations to deter the market entry by new (foreign) suppliers. Thus the free trade agreement TTIP affects in many respects regulatory provisions on and access to Electronic Communications markets. The objective of this paper is therefore to examine to what extend the regulatory principles for Electronic Communications markets envisaged under TTIP will result in trade facilitation and regulatory convergence between the EU and the U.S. As to this question the result of the analysis is that the chapter on Electronic Communications will be an important step towards facilitating trade in Electronic Communications services. At the same time some regulatory convergence will take place, but this convergence will not lead to a (full) harmonization of regulations. Rather the norm, also after TTIP negotiations will have been concluded successfully, will be mutual recognition of different regulatory regimes. Different regulations being the optimal policy response in different market settings will continue to exist. Moreover, it is very unlikely that such regulatory principles for the Electronic Communications sector are a vehicle for a race to the bottom in levels of consumer protection.}, language = {en} } @book{Gebhardt2016, author = {Gebhardt, Andreas}, title = {Additive Fertigungsverfahren : Additive Manufacturing und 3D-Drucken f{\"u}r Prototyping - Tooling - Produktion}, edition = {5. aktualisierte und erweiterte Auflage}, publisher = {Hanser}, address = {M{\"u}nchen}, isbn = {978-3-446-44401-0 ; 978-3-446-44539-0}, doi = {10.3139/9783446445390}, pages = {XXIV, 711 S. : zahlr. Ill. u. graph. Darst.}, year = {2016}, language = {de} } @article{KoenigVoelkerWolfetal.2016, author = {K{\"o}nig, Johannes Alexander and V{\"o}lker, Veronika and Wolf, Martin and Schuba, Marko}, title = {Gamified Hacking Offence Simulation-based Training (GHOST)}, series = {Crisis Prevention}, volume = {2016}, journal = {Crisis Prevention}, number = {3}, publisher = {Beta}, address = {Bonn}, pages = {44 -- 46}, year = {2016}, language = {de} } @inproceedings{FerreinMaierMuehlbacheretal.2016, author = {Ferrein, Alexander and Maier, Christopher and M{\"u}hlbacher, Clemens and Niem{\"u}ller, Tim and Steinbauer, Gerald and Vassos, Stravros}, title = {Controlling logistics robots with the action-based language YAGI}, series = {Intelligent Robotics and Applications: 9th International Conference, ICIRA 2016, Tokyo, Japan, August 22-24, 2016, Proceedings, Part I}, volume = {9834}, booktitle = {Intelligent Robotics and Applications: 9th International Conference, ICIRA 2016, Tokyo, Japan, August 22-24, 2016, Proceedings, Part I}, publisher = {Springer}, isbn = {978-3-319-43505-3 (Print)}, doi = {10.1007/978-3-319-43506-0_46}, pages = {525 -- 537}, year = {2016}, language = {en} } @inproceedings{NeumannDuelbergSchifferetal.2016, author = {Neumann, Tobias and D{\"u}lberg, Enno and Schiffer, Stefan and Ferrein, Alexander}, title = {A rotating platform for swift acquisition of dense 3D point clouds}, series = {Intelligent Robotics and Applications: 9th International Conference, ICIRA 2016, Tokyo, Japan, August 22-24, 2016, Proceedings, Part I}, volume = {9834}, booktitle = {Intelligent Robotics and Applications: 9th International Conference, ICIRA 2016, Tokyo, Japan, August 22-24, 2016, Proceedings, Part I}, publisher = {Springer}, isbn = {978-3-319-43505-3 (Print)}, doi = {10.1007/978-3-319-43506-0_22}, pages = {257 -- 268}, year = {2016}, language = {en} } @inproceedings{RuppKuperjansSchulze2016, author = {Rupp, Matthias and Kuperjans, Isabel and Schulze, Sven}, title = {Energetische und {\"o}kologische Bewertung hybrider Antriebe im st{\"a}dtischen Busverkehr}, series = {Commercial vehicle technology 2016 : proceedings of the 4th Commercial Vehicle Technology Symposium (CVT 2016), March 8-10, 2016, University of Kaiserslautern, Kaiserslautern, Germany}, booktitle = {Commercial vehicle technology 2016 : proceedings of the 4th Commercial Vehicle Technology Symposium (CVT 2016), March 8-10, 2016, University of Kaiserslautern, Kaiserslautern, Germany}, editor = {Berns, Karsten}, publisher = {Shaker}, address = {Aachen}, organization = {Internationales Commercial Vehicle Technology Symposium <4, 2016, Kaiserslautern>}, pages = {227 -- 237}, year = {2016}, abstract = {In Anbetracht weltweit zunehmend strengerer klimapolitischer Ziele steigt auch der Druck f{\"u}r Nutzfahrzeughersteller, effizientere und umweltfreundlichere Technologien zu entwickeln. Den Blick bei der Bewertung dieser ausschließlich auf die Fahrzeugnutzung zu richten, ist l{\"a}ngst nicht mehr zufriedenstellend. Im Rahmen dieser Analyse wird ein gegenw{\"a}rtig auf dem Markt erwerblicher und in deutschen St{\"a}dten bereits seit Jahren betriebener Hybridbus energetisch und {\"o}kologisch mit einem konventionell angetriebenen, nahezu baugleichen Modell entlang des Lebensweges bewertet. Nach Definition von Ziel und Untersuchungsrahmen wird ein {\"U}berblick auf bereits durchgef{\"u}hrte Lebenszyklusanalysen zu Hybridbussen im Stadtverkehr gegeben und Schlussfolgerungen f{\"u}r die anschließende Analyse abgeleitet. Diese wird im Rahmen einer energetischen und {\"o}kologischen Bewertung beider Produktsysteme anhand der Parameter "Prim{\"a}renergieeinsatz" und "CO2{\"a}q Emissionen" praktiziert. Der Fahrzeugrumpf beider Fahrzeuge des gleichen Modells wird dabei als einheitlich angenommen, sodass bei dem Vergleich der Herstellung vereinfacht nur die sich unterscheidenden Komponenten des Antriebstranges ber{\"u}cksichtigt werden. Die Resultate der Wirkungsabsch{\"a}tzung werden als Differenz des Hybridbusses gegen{\"u}ber dem Referenzfahrzeug {\"u}ber die einzelnen Lebenszyklusphasen dargestellt. Schließlich werden Prognosen getroffen, ab welcher Strecke die bei der Herstellung erzeugten h{\"o}heren CO2{\"a}q Emissionen des Hybridantriebstranges gegen{\"u}ber dem Referenzmodell ausgeglichen werden.}, language = {de} } @inproceedings{BhattaraiFrotscherStaat2016, author = {Bhattarai, Aroj and Frotscher, Ralf and Staat, Manfred}, title = {Significance of fibre geometry on passive-active response of pelvic muscles to evaluate pelvic dysfunction}, series = {BioMedWomen: Proceedings of the international conference on clinical and bioengineering for women's health}, booktitle = {BioMedWomen: Proceedings of the international conference on clinical and bioengineering for women's health}, editor = {Natal Jorge, Renato}, publisher = {CRC Press}, address = {Boca Raton}, isbn = {978-1-138-02910-1}, pages = {185 -- 188}, year = {2016}, language = {en} } @misc{Alt2016, author = {Alt, Helmut}, title = {Energiewende zwischen Wunsch und Wirklichkeit : Von der Grundlastdeckung zur L{\"u}ckenlastdeckung}, pages = {42 Folien}, year = {2016}, abstract = {Folien des Vortrags. VDI-Bezirksverband Dresden, Arbeitskreis Energietechnik, am Montag, 05.09.2016}, language = {de} } @article{Kern2016, author = {Kern, Alexander}, title = {Blitz- und {\"U}berspannungsschutz von Kernkraftwerken - Nachweisf{\"u}hrung der ausreichenden Sicherheit f{\"u}r leittechnische Einrichtungen auch bei Blitzeinschl{\"a}gen mit extremen Parametern}, series = {Atw. International Journal for Nuclear Power}, volume = {61}, journal = {Atw. International Journal for Nuclear Power}, number = {8/9}, publisher = {Inforum}, address = {Berlin}, issn = {1431-5254}, pages = {534 -- 543}, year = {2016}, abstract = {F{\"u}r das Auftreten extremer Wetterereignisse werden f{\"u}r Kernkraftwerke Eintrittsh{\"a}ufigkeiten f{\"u}r nicht mehr beherrschbare Zust{\"a}nde von unter 10⁻⁴/a gefordert. Dies gilt auch f{\"u}r die Einwirkung von Blitzeinschl{\"a}gen. Die bisherige Nachweisf{\"u}hrung zu Blitz- und {\"U}berspannungsschutz eines KKW in Deutschland ist deterministisch. In diesem Bericht werden das Vorgehen f{\"u}r einen entsprechenden Nachweis f{\"u}r leittechnische Einrichtungen der Sicherheitstechnik von KKW, der zur geforderten Zielgr{\"o}ße der Eintrittsh{\"a}ufigkeit f{\"u}hrt. Die Ergebnisse werden zusammenfassend bewertet.}, language = {de} } @article{WagnerVornholtWerneretal.2016, author = {Wagner, Torsten and Vornholt, Wolfgang and Werner, Frederik and Yoshinobu, Tatsuo and Miyamoto, Ko-Ichiro and Keusgen, Michael and Sch{\"o}ning, Michael Josef}, title = {Light-addressable potentiometric sensor (LAPS) combined with magnetic beads for pharmaceutical screening}, series = {Physics in medicine}, volume = {2016}, journal = {Physics in medicine}, number = {1}, issn = {2352-4510}, doi = {10.1016/j.phmed.2016.03.001}, pages = {2 -- 7}, year = {2016}, abstract = {The light-addressable potentiometric sensor (LAPS) has the unique feature to address different regions of a sensor surface without the need of complex structures. Measurements at different locations on the sensor surface can be performed in a common analyte solution, which distinctly simplifies the fluidic set-up. However, the measurement in a single analyte chamber prevents the application of different drugs or different concentrations of a drug to each measurement spot at the same time as in the case of multi-reservoir-based set-ups. In this work, the authors designed a LAPS-based set-up for cell culture screening that utilises magnetic beads loaded with the endotoxin (lipopolysaccharides, LPS), to generate a spatially distributed gradient of analyte concentration. Different external magnetic fields can be adjusted to move the magnetic beads loaded with a specific drug within the measurement cell. By recording the metabolic activities of a cell layer cultured on top of the LAPS surface, this work shows the possibility to apply different concentrations of a sample along the LAPS measurement spots within a common analyte solution.}, language = {en} } @article{DollWagnerWagneretal.2016, author = {Doll, Theodor and Wagner, Torsten and Wagner, Patrick and Sch{\"o}ning, Michael Josef}, title = {Engineering of functional interfaces / Theodor Doll ; Torsten Wagner ; Patrick Wagner ; Michael J. Sch{\"o}ning (eds.)}, series = {Physica status solidi (a)}, volume = {213}, journal = {Physica status solidi (a)}, number = {6}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {1862-6319}, doi = {10.1002/pssa.201670641}, pages = {1393 -- 1394}, year = {2016}, language = {en} } @article{KnobeGiesenPlateetal.2016, author = {Knobe, M. and Giesen, M. and Plate, S. and Gradl-Dietsch, G. and Buecking, B. and Eschbach, D. and Laack, Walter van and Pape, H.-C.}, title = {The Aachen mobility and balance index to measure physiological falls risk: a comparison with the Tinetti POMA scale}, series = {European Journal Of Trauma And Emergency Surgery}, volume = {42}, journal = {European Journal Of Trauma And Emergency Surgery}, number = {5}, publisher = {Springer}, address = {Berlin}, issn = {1863-9941}, doi = {10.1007/s00068-016-0693-2}, pages = {537 -- 545}, year = {2016}, abstract = {Purpose The most commonly used mobility assessments for screening risk of falls among older adults are rating scales such as the Tinetti performance oriented mobility assessment (POMA). However, its correlation with falls is not always predictable and disadvantages of the scale include difficulty to assess many of the items on a 3-point scale and poor specificity. The purpose of this study was to describe the ability of the new Aachen Mobility and Balance Index (AMBI) to discriminate between subjects with a fall history and subjects without such events in comparison to the Tinetti POMA Scale. Methods For this prospective cohort study, 24 participants in the study group and 10 in the control group were selected from a population of patients in our hospital who had met the stringent inclusion criteria. Both groups completed the Tinetti POMA Scale (gait and balance component) and the AMBI (tandem stance, tandem walk, ten-meter-walk-test, sit-to-stand with five repetitions, 360° turns, timed-up-and-go-test and measurement of the dominant hand grip strength). A history of falls and hospitalization in the past year were evaluated retrospectively. The relationships among the mobility tests were examined with Bland-Altmananalysis. Receiver-operated characteristics curves, sensitivity and specificity were calculated. Results The study showed a strong negative correlation between the AMBI (17 points max., highest fall risk) and Tinetti POMA Scale (28 points max., lowest fall risk; r = -0.78, p < 0.001) with an excellent discrimination between community-dwelling older people and a younger control group. However, there were no differences in any of the mobility and balance measurements between participants with and without a fall history with equal characteristics in test comparison (AMBI vs. Tinetti POMA Scale: AUC 0.570 vs. 0.598; p = 0.762). The Tinetti POMA Scale (cut-off <20 points) showed a sensitivity of 0.45 and a specificity of 0.69, the AMBI a sensitivity of 0.64 and a specificity of 0.46 (cut-off >5 points). Conclusion The AMBI comprises mobility and balance tasks with increasing difficulty as well as a measurement of the dominant hand-grip strength. Its ability to identify fallers was comparable to the Tinetti POMA Scale. However, both measurement sets showed shortcomings in discrimination between fallers and non-fallers based on a self-reported retrospective falls-status.}, language = {en} } @article{MolinnusSorichBartzetal.2016, author = {Molinnus, Denise and Sorich, Maren and Bartz, Alexander and Siegert, Petra and Willenberg, Holger S. and Lisdat, Fred and Poghossian, Arshak and Keusgen, Michael and Sch{\"o}ning, Michael Josef}, title = {Towards an adrenaline biosensor based on substrate recycling amplification in combination with an enzyme logic gate}, series = {Sensors and Actuators B: Chemical}, volume = {237}, journal = {Sensors and Actuators B: Chemical}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0925-4005}, doi = {10.1016/j.snb.2016.06.064}, pages = {190 -- 195}, year = {2016}, abstract = {An amperometric biosensor using a substrate recycling principle was realized for the detection of low adrenaline concentrations (1 nM) by measurements in phosphate buffer and Ringer's solution at pH 6.5 and pH 7.4, respectively. In proof-of-concept experiments, a Boolean logic-gate principle has been applied to develop a digital adrenaline biosensor based on an enzyme AND logic gate. The obtained results demonstrate that the developed digital biosensor is capable for a rapid qualitative determination of the presence/absence of adrenaline in a YES/NO statement. Such digital biosensor could be used in clinical diagnostics for the control of a correct insertion of a catheter in the adrenal veins during adrenal venous-sampling procedure.}, language = {en} } @inproceedings{FunkeKeinzBoerneretal.2016, author = {Funke, Harald and Keinz, Jan and B{\"o}rner, S. and Hendrick, P. and Elsing, R.}, title = {Testing and analysis of the impact on engine cycle parameters and control system modifications using hydrogen or methane as fuel in an industrial gas turbine}, series = {Progress in propulsion physics ; Volume 8}, booktitle = {Progress in propulsion physics ; Volume 8}, publisher = {EDP Sciences}, address = {o.O.}, organization = {European Conference for Aerospace Sciences <2013, M{\"u}nchen>}, isbn = {978-5-94588-191-4}, doi = {10.1051/eucass/201608409}, pages = {409 -- 426}, year = {2016}, language = {en} } @inproceedings{HarzheimHeuermannMarso2016, author = {Harzheim, Thomas and Heuermann, Holger and Marso, Michel}, title = {An Adaptive Biasing Method for SRD Comb Generators}, series = {2016 German Microwave Conference (GeMiC)}, booktitle = {2016 German Microwave Conference (GeMiC)}, publisher = {IEEE}, doi = {10.1109/GEMIC.2016.7461613}, pages = {289 -- 292}, year = {2016}, language = {en} } @article{ValeroBung2016, author = {Valero, Daniel and Bung, Daniel Bernhard}, title = {Development of the interfacial air layer in the non-aerated region of high-velocity spillway flows: Instabilities growth, entrapped air and influence on the self-aeration onset}, series = {International Journal of Multiphase Flow}, volume = {84}, journal = {International Journal of Multiphase Flow}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0301-9322}, doi = {10.1016/j.ijmultiphaseflow.2016.04.012}, pages = {66 -- 74}, year = {2016}, abstract = {Self-aeration is traditionally explained by the water turbulent boundary layer outer edge intersection with the free surface. This paper presents a discussion on the commonly accepted hypothesis behind the computation of the critical point of self-aeration in spillway flows and a new formulation is proposed based on the existence of a developing air flow over the free surface. Upstream of the inception point of self-aeration, some surface roughening has been often reported in previous studies which consequently implies some entrapped air transport and air-water flows coupling. Such air flow is proven in this study by presenting measured air velocities and computing the air boundary layer thickness for a 1V:2H smooth chute flow. Additionally, the growth rate of free surface waves has been analysed by means of Ultrasonic Sensors measurements, obtaining also the entrapped air concentration. High-speed camera imaging has been used for qualitative study of the flow perturbations.}, language = {en} } @article{GhoschBaierSchuetzetal.2016, author = {Ghosch, S. and Baier, M. and Sch{\"u}tz, J. and Schneider, Felix and Scherer, Ulrich W.}, title = {Analysis of electronic autoradiographs by mathematical post-processing}, series = {Radiation Effects and Defects in Solids: Incorporating plasma science and plasma technology}, volume = {171}, journal = {Radiation Effects and Defects in Solids: Incorporating plasma science and plasma technology}, number = {1-2}, publisher = {Taylor \& Francis}, address = {London}, issn = {1029-4953}, doi = {10.1080/10420150.2016.1155587}, pages = {161 -- 172}, year = {2016}, abstract = {Autoradiography is a well-established method of nuclear imaging. When different radionuclides are present simultaneously, additional processing is needed to distinguish distributions of radionuclides. In this work, a method is presented where aluminium absorbers of different thickness are used to produce images with different cut-off energies. By subtracting images pixel-by-pixel one can generate images representing certain ranges of β-particle energies. The method is applied to the measurement of irradiated reactor graphite samples containing several radionuclides to determine the spatial distribution of these radionuclides within pre-defined energy windows. The process was repeated under fixed parameters after thermal treatment of the samples. The greyscale images of the distribution after treatment were subtracted from the corresponding pre-treatment images. Significant changes in the intensity and distribution of radionuclides could be observed in some samples. Due to the thermal treatment parameters the most significant differences were observed in the ³H and ¹⁴C inventory and distribution.}, language = {en} } @inproceedings{BroennerHoefkenSchuba2016, author = {Broenner, Simon and H{\"o}fken, Hans-Wilhelm and Schuba, Marko}, title = {Streamlining extraction and analysis of android RAM images}, series = {Proceedings of the 2nd international conference on information systems security and privacy}, booktitle = {Proceedings of the 2nd international conference on information systems security and privacy}, organization = {ICISSP International Conference on Information Systems Security and Privacy <2, 2016, Rome, Italy>}, isbn = {978-989-758-167-0}, doi = {10.5220/0005652802550264}, pages = {255 -- 264}, year = {2016}, language = {en} } @article{KolditzAlbinAbeletal.2016, author = {Kolditz, Melanie and Albin, Thivaharan and Abel, Dirk and Fasse, Alessandro and Br{\"u}ggemann, Gert-Peter and Albracht, Kirsten}, title = {Evaluation of foot position and orientation as manipulated variables to control external knee adduction moments in leg extension training}, series = {Computer methods and programs in biomedicine}, volume = {171}, journal = {Computer methods and programs in biomedicine}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0169-2607}, doi = {10.1016/j.cmpb.2016.09.005}, pages = {81 -- 86}, year = {2016}, abstract = {Background and Objective Effective leg extension training at a leg press requires high forces, which need to be controlled to avoid training-induced damage. In order to avoid high external knee adduction moments, which are one reason for unphysiological loadings on knee joint structures, both training movements and the whole reaction force vector need to be observed. In this study, the applicability of lateral and medial changes in foot orientation and position as possible manipulated variables to control external knee adduction moments is investigated. As secondary parameters both the medio-lateral position of the center of pressure and the frontal-plane orientation of the reaction force vector are analyzed. Methods Knee adduction moments are estimated using a dynamic model of the musculoskeletal system together with the measured reaction force vector and the motion of the subject by solving the inverse kinematic and dynamic problem. Six different foot conditions with varying positions and orientations of the foot in a static leg press are evaluated and compared to a neutral foot position. Results Both lateral and medial wedges under the foot and medial and lateral shifts of the foot can influence external knee adduction moments in the presented study with six healthy subjects. Different effects are observed with the varying conditions: the pose of the leg is changed and the direction and center of pressure of the reaction force vector is influenced. Each effect results in a different direction or center of pressure of the reaction force vector. Conclusions The results allow the conclusion that foot position and orientation can be used as manipulated variables in a control loop to actively control knee adduction moments in leg extension training.}, language = {en} }