@inproceedings{SchubaHoefkenLinzbach2022,
  author    = {Schuba, Marko and H{\"o}fken, Hans-Wilhelm and Linzbach, Sophie},
  title     = {An ICS Honeynet for Detecting and Analyzing Cyberattacks in Industrial Plants},
  series = {2021 International Conference on Electrical, Computer and Energy Technologies (ICECET)},
  booktitle = {2021 International Conference on Electrical, Computer and Energy Technologies (ICECET)},
  publisher = {IEEE},
  isbn      = {978-1-6654-4231-2},
  doi       = {10.1109/ICECET52533.2021.9698746},
  pages     = {6 Seiten},
  year      = {2022},
  abstract  = {Cybersecurity of Industrial Control Systems (ICS) is an important issue, as ICS incidents may have a direct impact on safety of people or the environment. At the same time the awareness and knowledge about cybersecurity, particularly in the context of ICS, is alarmingly low. Industrial honeypots offer a cheap and easy to implement way to raise cybersecurity awareness and to educate ICS staff about typical attack patterns. When integrated in a productive network, industrial honeypots may not only reveal attackers early but may also distract them from the actual important systems of the network. Implementing multiple honeypots as a honeynet, the systems can be used to emulate or simulate a whole Industrial Control System. This paper describes a network of honeypots emulating HTTP, SNMP, S7communication and the Modbus protocol using Conpot, IMUNES and SNAP7. The nodes mimic SIMATIC S7 programmable logic controllers (PLCs) which are widely used across the globe. The deployed honeypots' features will be compared with the features of real SIMATIC S7 PLCs. Furthermore, the honeynet has been made publicly available for ten days and occurring cyberattacks have been analyzed},
  language  = {en}
}
@article{StaeudleSeynnesLapsetal.2022,
  author    = {St{\"a}udle, Benjamin and Seynnes, Olivier and Laps, Guido and Br{\"u}ggemann, Gert-Peter and Albracht, Kirsten},
  title     = {Altered gastrocnemius contractile behavior in former achilles tendon rupture patients during walking},
  series = {Frontiers in Physiology},
  volume    = {13},
  journal   = {Frontiers in Physiology},
  publisher = {Frontiers Research Foundation},
  address   = {Lausanne},
  issn      = {1664-042X},
  doi       = {10.3389/fphys.2022.792576},
  pages     = {12 Seiten},
  year      = {2022},
  abstract  = {Achilles tendon rupture (ATR) remains associated with functional limitations years after injury. Architectural remodeling of the gastrocnemius medialis (GM) muscle is typically observed in the affected leg and may compensate force deficits caused by a longer tendon. Yet patients seem to retain functional limitations during—low-force—walking gait. To explore the potential limits imposed by the remodeled GM muscle-tendon unit (MTU) on walking gait, we examined the contractile behavior of muscle fascicles during the stance phase. In a cross-sectional design, we studied nine former patients (males; age: 45 ± 9 years; height: 180 ± 7 cm; weight: 83 ± 6 kg) with a history of complete unilateral ATR, approximately 4 years post-surgery. Using ultrasonography, GM tendon morphology, muscle architecture at rest, and fascicular behavior were assessed during walking at 1.5 m⋅s-1 on a treadmill. Walking patterns were recorded with a motion capture system. The unaffected leg served as control. Lower limbs kinematics were largely similar between legs during walking. Typical features of ATR-related MTU remodeling were observed during the stance sub-phases corresponding to series elastic element (SEE) lengthening (energy storage) and SEE shortening (energy release), with shorter GM fascicles (36 and 36\%, respectively) and greater pennation angles (8° and 12°, respectively). However, relative to the optimal fascicle length for force production, fascicles operated at comparable length in both legs. Similarly, when expressed relative to optimal fascicle length, fascicle contraction velocity was not different between sides, except at the time-point of peak series elastic element (SEE) length, where it was 39 ± 49\% lower in the affected leg. Concomitantly, fascicles rotation during contraction was greater in the affected leg during the whole stance-phase, and architectural gear ratios (AGR) was larger during SEE lengthening. Under the present testing conditions, former ATR patients had recovered a relatively symmetrical walking gait pattern. Differences in seen AGR seem to accommodate the profound changes in MTU architecture, limiting the required fascicle shortening velocity. Overall, the contractile behavior of the GM fascicles does not restrict length- or velocity-dependent force potentials during this locomotor task.},
  language  = {en}
}
@article{UysalFiratCreutzetal.2022,
  author    = {Uysal, Karya and Firat, Ipek Serat and Creutz, Till and Aydin, Inci Cansu and Artmann, Gerhard and Teusch, Nicole and Temiz Artmann, Ayseg{\"u}l},
  title     = {A novel in vitro wound healing assay using free-standing, ultra-thin PDMS membranes},
  series = {membranes},
  volume    = {2023},
  journal   = {membranes},
  number    = {13(1)},
  publisher = {MDPI},
  address   = {Basel},
  doi       = {10.3390/membranes13010022},
  pages     = {Artikel 22},
  year      = {2022},
  abstract  = {Advances in polymer science have significantly increased polymer applications in life sciences. We report the use of free-standing, ultra-thin polydimethylsiloxane (PDMS) membranes, called CellDrum, as cell culture substrates for an in vitro wound model. Dermal fibroblast monolayers from 28- and 88-year-old donors were cultured on CellDrums. By using stainless steel balls, circular cell-free areas were created in the cell layer (wounding). Sinusoidal strain of 1 Hz, 5\% strain, was applied to membranes for 30 min in 4 sessions. The gap circumference and closure rate of un-stretched samples (controls) and stretched samples were monitored over 4 days to investigate the effects of donor age and mechanical strain on wound closure. A significant decrease in gap circumference and an increase in gap closure rate were observed in trained samples from younger donors and control samples from older donors. In contrast, a significant decrease in gap closure rate and an increase in wound circumference were observed in the trained samples from older donors. Through these results, we propose the model of a cell monolayer on stretchable CellDrums as a practical tool for wound healing research. The combination of biomechanical cell loading in conjunction with analyses such as gene/protein expression seems promising beyond the scope published here.},
  language  = {en}
}
@article{HarrisKleefeld2022,
  author    = {Harris, Isaac and Kleefeld, Andreas},
  title     = {Analysis and computation of the transmission eigenvalues with a conductive boundary condition},
  series = {Applicable Analysis},
  volume    = {101},
  journal   = {Applicable Analysis},
  number    = {6},
  publisher = {Taylor \& Francis},
  address   = {London},
  issn      = {1563-504X},
  doi       = {10.1080/00036811.2020.1789598},
  pages     = {1880 -- 1895},
  year      = {2022},
  abstract  = {We provide a new analytical and computational study of the transmission eigenvalues with a conductive boundary condition. These eigenvalues are derived from the scalar inverse scattering problem for an inhomogeneous material with a conductive boundary condition. The goal is to study how these eigenvalues depend on the material parameters in order to estimate the refractive index. The analytical questions we study are: deriving Faber-Krahn type lower bounds, the discreteness and limiting behavior of the transmission eigenvalues as the conductivity tends to infinity for a sign changing contrast. We also provide a numerical study of a new boundary integral equation for computing the eigenvalues. Lastly, using the limiting behavior we will numerically estimate the refractive index from the eigenvalues provided the conductivity is sufficiently large but unknown.},
  language  = {en}
}
@misc{KrafftKukaUlberetal.2022,
  author    = {Krafft, Simone and Kuka, Katrin and Ulber, Roland and Tippk{\"o}tter, Nils},
  title     = {Utilization of Lolium perenne varieties as a renewable substrate for single-cell proteins, lactate, and composite materials},
  series = {Chemie Ingenieur Technik},
  volume    = {94},
  journal   = {Chemie Ingenieur Technik},
  number    = {9},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {0009-286X},
  doi       = {10.1002/cite.202255306},
  pages     = {1303 -- 1304},
  year      = {2022},
  abstract  = {Lolium perenne (perennial ryegrass) is aproductive and high-quality forage grass indigenous to Southern Europe, temperate Asia, and North Africa. Nowadays it is widespread and the dominant grass species on green areas in temperate climates. This abundant source of biomass is suitable for the development of bioeconomic processes because of its high cellulose and water-soluble carbohydrate content. In this work, novel breeds of the perennial ryegrass are being examined with regards to their quality parameters and biotechnological utilization options within the context of bioeconomy. Three processing operations are presented. In the first process, the perennial ryegrass is pretreated by pressing or hydrothermal extraction to derive glucosevia subsequent enzymatic hydrolysis of cellulose. A yield of up to 82 \% glucose was achieved when using the hydrothermal ex-traction as pretreatment. In a second process, the ryegrass is used to produce lactic acid in high concentrations. The influence of the growth conditions and the cutting time on the carboxylic acid yield is investigated. A yield of lactic acid of above 150 g kg⁻¹ dry matter was achieved. The third process is to use Lolium perenne as a substrate in the fermentation of K. marxianus for the microbial production of single-cell proteins. The perennial ryegrass is screw-pressed and the press juice is used as medium. When supplementing the press juice with yeast media components, a biomass concentration of up to 16 g L⁻¹ could be achieved.},
  language  = {en}
}
@misc{RothkranzKrafftTippkoetter2022,
  author    = {Rothkranz, Berit and Krafft, Simone and Tippk{\"o}tter, Nils},
  title     = {Media optimization for sustainable fuel production: How to produce biohydrogen from renewable resources with Thermotoga neapolitana},
  series = {Chemie Ingenieur Technik},
  volume    = {94},
  journal   = {Chemie Ingenieur Technik},
  number    = {9},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {0009-286X},
  doi       = {10.1002/cite.202255305},
  pages     = {1298 -- 1299},
  year      = {2022},
  abstract  = {Hydrogen is playing an increasingly important role in research and politics as an energy carrier of the future. Since hydrogen has commonly been produced from methane by steam reforming, the need for climate-friendly, alternative production routes is emerging. In addition to electrolysis, fermentative routes for the production of so-called biohydrogen are "green" alternatives. The application of microorganisms offers the advantage of sustainable production from renewable resources using easily manageable technologies. In this project, the hyperthermophilic, anaerobic microorganism Thermotoga neapolitana is used for the productio nof biohydrogen from renewable resources. The enzymatically hydrolyzed resources were used in fermentation leading to yield coefficients of 1.8 mole H₂ per mole glucose when using hydrolyzed straw and ryegrass supplemented with medium, respectively. These results are similar to the hydrogen yields when using Thermotoga basal medium with glucose (TBGY) as control group. In order to minimize the supplementation of the hydrolysate and thus increase the economic efficiency of the process, the essential media components were identified. The experiments revealed NaCl, KCl, and glucose as essential components for cell growth as well as biohydrogen production. When excluding NaCl, a decrease of 96\% in hydrogen production occured.},
  language  = {en}
}
@article{GaigallGerstenbergTrinh2022,
  author    = {Gaigall, Daniel and Gerstenberg, Julian and Trinh, Thi Thu Ha},
  title     = {Empirical process of concomitants for partly categorial data and applications in statistics},
  series = {Bernoulli},
  volume    = {28},
  journal   = {Bernoulli},
  number    = {2},
  publisher = {International Statistical Institute},
  address   = {Den Haag, NL},
  issn      = {1573-9759},
  doi       = {10.3150/21-BEJ1367},
  pages     = {803 -- 829},
  year      = {2022},
  abstract  = {On the basis of independent and identically distributed bivariate random vectors, where the components are categorial and continuous variables, respectively, the related concomitants, also called induced order statistic, are considered. The main theoretical result is a functional central limit theorem for the empirical process of the concomitants in a triangular array setting. A natural application is hypothesis testing. An independence test and a two-sample test are investigated in detail. The fairly general setting enables limit results under local alternatives and bootstrap samples. For the comparison with existing tests from the literature simulation studies are conducted. The empirical results obtained confirm the theoretical findings.},
  language  = {en}
}
@article{Timme2022,
  author    = {Timme, Michael},
  title     = {Beweislast beim gutgl{\"a}ubigen Erwerb eines Kraftfahrzeugs ohne Erhalt der Zulassungsbescheinigung Teil II — Zugleich eine Besprechung von BGH, Urt. v. 23.9.2022 - V ZR 148/21, MDR 2022, 1542},
  series = {Monatsschrift f{\"u}r Deutsches Recht},
  volume    = {77},
  journal   = {Monatsschrift f{\"u}r Deutsches Recht},
  number    = {1},
  publisher = {Verlag Dr. Otto Schmidt},
  address   = {K{\"o}ln},
  issn      = {0340-1812},
  doi       = {doi.org/10.9785/mdtr-2023-770102},
  pages     = {r5 -- r7},
  year      = {2022},
  abstract  = {Im Handel mit Kraftfahrzeugen geh{\"o}ren Aspekte des gutgl{\"a}ubigen Erwerbs zu den beinahe allt{\"a}glichen Standardproblemen. Der BGH f{\"u}gt in seiner Entscheidung v. 23.9.2022-VZR148/21, MDR 2022, 1541 diesem im Detail breit gef{\"a}cherten Themenfeld einen weiteren Mosaikstein hinzu: Der Erwerber erhielt das verkaufte Kfz ohne {\"U}bergabe einer Zulassungsbescheinigung Teil II, behauptet aber, diese Bescheinigung sei dem vom ihm eingeschalteten Vermittler bei Erwerb (als F{\"a}lschung) vorgelegt worden. Tats{\"a}chlich befand sich das Original durchg{\"a}ngig beim wahren Eigent{\"u}mer, der nunmehr Herausgabe des Fahrzeugs verlangt. Der BGH sch{\"u}tzt in dieser Gestaltung im Ergebnis den Erwerber. Die Entscheidung ist in mehrfacher Hinsicht bemerkenswert.},
  language  = {de}
}
@inproceedings{LangohrBungCrookston2022,
  author    = {Langohr, Philipp and Bung, Daniel Bernhard and Crookston, Brian M.},
  title     = {Hybrid investigation of labyrinth weirs: Discharge capacity and energy dissipation},
  series = {Proceedings of the 39th IAHR World Congress},
  booktitle = {Proceedings of the 39th IAHR World Congress},
  editor    = {Ortega-S{\´a}nchez, Miguel},
  publisher = {International Association for Hydro-Environment Engineering and Research (IAHR)},
  address   = {Madrid},
  isbn      = {978-90-832612-1-8},
  issn      = {2521-7119 (print)},
  doi       = {10.3850/IAHR-39WC252171192022738},
  pages     = {2313 -- 2318},
  year      = {2022},
  abstract  = {The replacement of existing spillway crests or gates with labyrinth weirs is a proven techno-economical means to increase the discharge capacity when rehabilitating existing structures. However, additional information is needed regarding energy dissipation of such weirs, since due to the folded weir crest, a three-dimensional flow field is generated, yielding more complex overflow and energy dissipation processes. In this study, CFD simulations of labyrinth weirs were conducted 1) to analyze the discharge coefficients for different discharges to compare the Cd values to literature data and 2) to analyze and improve energy dissipation downstream of the structure. All tests were performed for a structure at laboratory scale with a height of approx. P = 30.5 cm, a ratio of the total crest length to the total width of 4.7, a sidewall angle of 10° and a quarter-round weir crest shape. Tested headwater ratios were 0.089 ≤ HT/P ≤ 0.817. For numerical simulations, FLOW-3D Hydro was employed, solving the RANS equations with use of finite-volume method and RNG k-ε turbulence closure. In terms of discharge capacity, results were compared to data from physical model tests performed at the Utah Water Research Laboratory (Utah State University), emphasizing higher discharge coefficients from CFD than from the physical model. For upstream heads, some discrepancy in the range of ± 1 cm between literature, CFD and physical model tests was identified with a discussion regarding differences included in the manuscript. For downstream energy dissipation, variable tailwater depths were considered to analyze the formation and sweep-out of a hydraulic jump. It was found that even for high discharges, relatively low downstream Froude numbers were obtained due to high energy dissipation involved by the three-dimensional flow between the sidewalls. The effects of some additional energy dissipation devices, e.g. baffle blocks or end sills, were also analyzed. End sills were found to be non-effective. However, baffle blocks with different locations may improve energy dissipation downstream of labyrinth weirs.},
  language  = {en}
}
@misc{VarrialeKukaTippkoetteretal.2022,
  author    = {Varriale, Ludovica and Kuka, Katrin and Tippk{\"o}tter, Nils and Ulber, Roland},
  title     = {Use of a green biomass in a biorefinery platform},
  series = {Chemie Ingenieur Technik},
  volume    = {94},
  journal   = {Chemie Ingenieur Technik},
  number    = {9},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {0009-286X},
  doi       = {10.1002/cite.202255095},
  pages     = {1299},
  year      = {2022},
  abstract  = {The emerging environmental issues due to the use of fossil resources are encouraging the exploration of new renewable resources. Biomasses are attracting more interest due to the low environmental impacts, low costs, and high availability on earth. In this scenario, green biorefineries are a promising platform in which green biomasses are used as feedstock. Grasses are mainly composed of cellulose and hemicellulose, and lignin is available in a small amount. In this work, a perennial ryegrass was used as feedstock to develop a green bio-refinery platform. Firstly, the grass was mechanically pretreated, thus obtaining a press juice and a press cake fraction. The press juice has high nutritional values and can be employed as part of fermentation media. The press cake can be employed as a substrate either in enzymatic hydrolysis or in solid-state fermentation. The overall aim of this work was to demonstrate different applications of both the liquid and the solid fractions. For this purpose, the filamentous fungus A. niger and the yeast Y. lipolythica were selected for their ability to produce citric acid. Finally, the possibility was assessed to use the press juice as part of fermentation media to cultivate S. cerevisiae and lactic acid bacteria for ethanol and lactic acid fermentation.},
  language  = {en}
}
@article{KahmannRauschPluemeretal.2022,
  author    = {Kahmann, Stephanie Lucina and Rausch, Valentin and Pl{\"u}mer, Jonathan and M{\"u}ller, Lars-Peter and Pieper, Martin and Wegmann, Kilian},
  title     = {The automized fracture edge detection and generation of three-dimensional fracture probability heat maps},
  series = {Medical Engineering \& Physics},
  volume    = {2022},
  journal   = {Medical Engineering \& Physics},
  number    = {110},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1350-4533},
  pages     = {7 Seiten},
  year      = {2022},
  abstract  = {With proven impact of statistical fracture analysis on fracture classifications, it is desirable to minimize the manual work and to maximize repeatability of this approach. We address this with an algorithm that reduces the manual effort to segmentation, fragment identification and reduction. The fracture edge detection and heat map generation are performed automatically. With the same input, the algorithm always delivers the same output. The tool transforms one intact template consecutively onto each fractured specimen by linear least square optimization, detects the fragment edges in the template and then superimposes them to generate a fracture probability heat map. We hypothesized that the algorithm runs faster than the manual evaluation and with low (< 5 mm) deviation. We tested the hypothesis in 10 fractured proximal humeri and found that it performs with good accuracy (2.5 mm ± 2.4 mm averaged Euclidean distance) and speed (23 times faster). When applied to a distal humerus, a tibia plateau, and a scaphoid fracture, the run times were low (1-2 min), and the detected edges correct by visual judgement. In the geometrically complex acetabulum, at a run time of 78 min some outliers were considered acceptable. An automatically generated fracture probability heat map based on 50 proximal humerus fractures matches the areas of high risk of fracture reported in medical literature. Such automation of the fracture analysis method is advantageous and could be extended to reduce the manual effort even further.},
  language  = {en}
}
@article{LenzKahmannBehbahanietal.2022,
  author    = {Lenz, Maximilian and Kahmann, Stephanie Lucina and Behbahani, Mehdi and Pennig, Lenhard and Hackl, Michael and Leschinger, Tim and M{\"u}ller, Lars-Peter and Wegmann, Kilian},
  title     = {Influence of rotator cuff preload on fracture configuration in proximal humerus fractures: a proof of concept for fracture simulation},
  series = {Archives of Orthopaedic and Trauma Surgery},
  journal   = {Archives of Orthopaedic and Trauma Surgery},
  publisher = {Springer},
  address   = {Berlin, Heidelberg},
  issn      = {1434-3916},
  doi       = {10.1007/s00402-022-04471-9},
  year      = {2022},
  abstract  = {Introduction In regard of surgical training, the reproducible simulation of life-like proximal humerus fractures in human cadaveric specimens is desirable. The aim of the present study was to develop a technique that allows simulation of realistic proximal humerus fractures and to analyse the influence of rotator cuff preload on the generated lesions in regards of fracture configuration. Materials and methods Ten cadaveric specimens (6 left, 4 right) were fractured using a custom-made drop-test bench, in two groups. Five specimens were fractured without rotator cuff preload, while the other five were fractured with the tendons of the rotator cuff preloaded with 2 kg each. The humeral shaft and the shortened scapula were potted. The humerus was positioned at 90° of abduction and 10° of internal rotation to simulate a fall on the elevated arm. In two specimens of each group, the emergence of the fractures was documented with high-speed video imaging. Pre-fracture radiographs were taken to evaluate the deltoid-tuberosity index as a measure of bone density. Post-fracture X-rays and CT scans were performed to define the exact fracture configurations. Neer's classification was used to analyse the fractures. Results In all ten cadaveric specimens life-like proximal humerus fractures were achieved. Two III-part and three IV-part fractures resulted in each group. The preloading of the rotator cuff muscles had no further influence on the fracture configuration. High-speed videos of the fracture simulation revealed identical fracture mechanisms for both groups. We observed a two-step fracture mechanism, with initial impaction of the head segment against the glenoid followed by fracturing of the head and the tuberosities and then with further impaction of the shaft against the acromion, which lead to separation of the tuberosities. Conclusion A high energetic axial impulse can reliably induce realistic proximal humerus fractures in cadaveric specimens. The preload of the rotator cuff muscles had no influence on initial fracture configuration. Therefore, fracture simulation in the proximal humerus is less elaborate. Using the presented technique, pre-fractured specimens are available for real-life surgical education.},
  language  = {en}
}
@masterthesis{Plura2022,
  type      = {Bachelor Thesis},
  author    = {Plura, Annika},
  title     = {Health Literacy : Konzeption und Entwurf eines digitalen Informationsangebots zum Thema Gesundheit},
  publisher = {FH Aachen},
  address   = {Aachen},
  pages     = {63 Seiten},
  year      = {2022},
  abstract  = {Nicht zuletzt die Corona-Pandemie hat gezeigt: Gesundheit geht alle Menschen etwas an. Vom Begriff „Health Literacy" haben viele aber noch nie geh{\"o}rt. Damit gemeint ist die menschliche Gesundheitskompetenz, also die F{\"a}higkeit, mit gesundheitsrelevanten Informationen richtig umzugehen und daraus selbstbestimmte Entscheidungen in Gesundheitsfragen ableiten zu k{\"o}nnen. In dieser Arbeit wurden dazu wichtige Aspekte aus der Studie HLS-GER 1 interaktiv und erlebbar aufbereitet. Durch das ausgew{\"a}hlte Informationsdesign wird die Thematik zug{\"a}nglich gemacht und aufgezeigt, welche gravierenden Auswirkungen schlecht ausgebildete Health Literacy auf die Selbstbestimmtheit und Chancengleichheit der Menschen hat. "Health Literacy" legt den Finger in die Wunde und zeigt, dass vor allem im Bildungskontext noch sehr viel Handlungsbedarf ist.},
  language  = {de}
}
@masterthesis{NiggeMans2022,
  type      = {Bachelor Thesis},
  author    = {Nigge-Mans, Leonard},
  title     = {Entwicklung einer Arbeitsplatzleuchte},
  publisher = {FH Aachen},
  address   = {Aachen},
  pages     = {74 Seiten},
  year      = {2022},
  abstract  = {F{\"u}r manche mag es banal wirken, doch f{\"u}r Gestalter:innen ist sie unverzichtbar: eine wirklich gute Leuchte f{\"u}r den Arbeitsplatz. Sie hat n{\"a}mlich einen enormen Einfluss auf die Konzentration und den Komfort. Zudem erm{\"o}glicht gutes Licht erst ein sauberes und farbechtes Ergebnis. Daf{\"u}r wurde in diesem Projekt die perfekte Leuchte entwickelt. Sie leuchtet die Arbeitsfl{\"a}che ideal aus und unterst{\"u}tzt das Lesen, Schreiben oder die Arbeit mit technischen Ger{\"a}ten. Durch f{\"u}nf Drehpunkte ist die Leuchte in alle Richtungen zu bewegen und l{\"a}sst sich somit individuell auf ihre Aufgaben anpassen. Außerdem wurde Wert daraufgelegt, bestehende Normen und Vorschiften einzuhalten, um den Arbeit- und Gesundheitsschutz zu gew{\"a}hrleisten. Feierabend? Durch die Dim-Funktion wird die Arbeitsleuchte zu einer gem{\"u}tlichen Lichtquelle. Unter anderem durch die unsichtbare Stromf{\"u}hrung {\"u}berzeugt die Lampe mit ihrer minimalistischen Designsprache und l{\"a}sst sich in unterschiedlichste R{\"a}ume integrieren.},
  language  = {de}
}
@masterthesis{Meesters2022,
  type      = {Bachelor Thesis},
  author    = {Meesters, Elena},
  title     = {Gestaltung eines h{\"a}uslichen Telemonitoringsystems zur Prognose kardialer Dekompensation},
  publisher = {FH Aachen},
  address   = {Aachen},
  pages     = {113 Seiten},
  year      = {2022},
  abstract  = {Herzinsuffizienz ist eine der h{\"a}ufigsten Herzerkrankungen in Deutschland. Sie ist fortschreitend und nicht heilbar. Der Krankheitsverlauf ist gepr{\"a}gt von pl{\"o}tzlichen, z.T. lebensbedrohlichen Verschlechterungen und Krankenhauseinweisungen, nach denen die Leistung des Herzen vermindert bleibt. Diese Dekompensationen lassen sich bisher im heimischen Umfeld nicht durch Messwerte vorhersehen. Dieses Ger{\"a}t bestimmt die Fl{\"u}ssigkeitsansammlungen in der Lunge, die ein mittelfristiges Symptom einer Dekompensation sind. Außerdem misst es {\"u}ber einen Hautsensor die im Schweiß enthaltene Menge eines Proteins, das bei {\"U}berdehnung des Herzmuskels vermehrt im Blutplasma zu finden ist. So k{\"o}nnen Dekompensationen bis zu zwei Wochen vor einem akuten Ereignis detektiert und behandelt werden. Außerdem gibt es tagesformabh{\"a}ngige Tipps f{\"u}r die Alltagsgestaltung mit der Erkrankung.},
  language  = {de}
}
@masterthesis{Menrath2022,
  type      = {Bachelor Thesis},
  author    = {Menrath, Maike},
  title     = {Konzept zur Lebensmittelnahversorgung außerhalb urbaner Strukturen : Verkaufspunkt f{\"u}r l{\"a}ndliche Gebiete},
  publisher = {FH Aachen},
  address   = {Aachen},
  pages     = {131 Seiten},
  year      = {2022},
  abstract  = {L{\"a}ndliche Regionen sind h{\"a}ufig infrastrukturell schlechter versorgt als urbane R{\"a}ume, was sich insbesondere auf die Versorgung mit G{\"u}tern des t{\"a}glichen Bedarfs niederschl{\"a}gt. Menschen außerhalb st{\"a}dtischer Ballungsgebiete m{\"u}ssen deswegen oft lange Anfahrten zu Superm{\"a}rkten in Kauf nehmen. Hierbei sind sie vor allem auf das Auto angewiesen. In dieser Arbeit ist „ILSE" entstanden. Eine Verkaufsbox, die Menschen in l{\"a}ndlichen Raumstrukturen besser mit Waren versorgt, indem sie dort aufgestellt wird, wo sie auch wirklich ben{\"o}tigt wird. Dank digitaler Verkaufstechnologien ist „ILSE" durchgehend ge{\"o}ffnet, auch, wenn andere Superm{\"a}rkte l{\"a}ngst geschlossen sind. Mit einer App wird der Kundschaft der Zugang zum Verkaufsraum und das Bezahlen erm{\"o}glicht.},
  language  = {de}
}
@techreport{GhinaiyaLehmannGoettsche2022,
  author    = {Ghinaiya, Jagdishkumar and Lehmann, Thomas Martin and G{\"o}ttsche, Joachim},
  title     = {LOCAL+ - ein kreislauff{\"a}higer Holzmodulbau mit nachhaltigem Energie- und Wohnraumkonzept},
  series = {Bauphysik},
  volume    = {44},
  journal   = {Bauphysik},
  number    = {3},
  publisher = {Ernst \& Sohn},
  address   = {Hoboken},
  issn      = {0171-5445 (Print)},
  doi       = {10.1002/bapi.202200010},
  pages     = {136 -- 142},
  year      = {2022},
  abstract  = {Mit dem Beitrag des Teams der FH Aachen zum SDE 21/22 wird im Projekt LOCAL+ ein kreislauff{\"a}higer Holzmodulbau mit einem innovativen Wohnraumkonzept geplant und umgesetzt. Ziel dieses Konzeptes ist die Verringerung des stetig steigenden Wohnfl{\"a}chenbedarfs durch ein Raum-in-Raum Konzept. Geb{\"a}udetechnisch wird in dem Projekt nicht nur das Einzelgeb{\"a}ude betrachtet, sondern unter Ber{\"u}cksichtigung des Geb{\"a}udebestandes wird f{\"u}r das Quartier ein innovatives und nachhaltiges Energiekonzept entwickelt. Ein zentrales Wasserstoffsystem ist f{\"u}r ein Quartier geplant, um den Stromverbrauch aus dem Netz im Winter zu reduzieren. Zentraler Bestandteil des TGA-Konzepts ist ein unterirdischer Eisspeicher, eine PVT und eine W{\"a}rmepumpe mit intelligenter Regelstrategie. Ein Teil des neuen Geb{\"a}udes (Design Challenge DC) wird in Wuppertal als Hausdemonstrationseinheit (HDU) pr{\"a}sentiert. Eine hygrothermische Simulation der HDU wurde mit der WUFI-Software durchgef{\"u}hrt. Da im Innenraum Lehmmodule und -platten als Feuchtigkeitspuffer verwendet werden, spielen die Themen Feuchtigkeit, Holzf{\"a}ule und Schimmelwachstum eine wichtige Rolle.},
  language  = {de}
}
@article{BernauKnoedlerEmontsetal.2022,
  author    = {Bernau, C. R. and Kn{\"o}dler, Matthias and Emonts, Jessica and J{\"a}pel, Ronald Colin and Buyel, Johannes Felix},
  title     = {The use of predictive models to develop chromatography-based purification processes},
  series = {Frontiers in Bioengineering and Biotechnology},
  journal   = {Frontiers in Bioengineering and Biotechnology},
  number    = {10},
  publisher = {Frontiers Media},
  address   = {Lausanne},
  issn      = {2296-4185 (online-ressource)},
  doi       = {10.3389/fbioe.2022.1009102},
  pages     = {25 Seiten},
  year      = {2022},
  abstract  = {Chromatography is the workhorse of biopharmaceutical downstream processing because it can selectively enrich a target product while removing impurities from complex feed streams. This is achieved by exploiting differences in molecular properties, such as size, charge and hydrophobicity (alone or in different combinations). Accordingly, many parameters must be tested during process development in order to maximize product purity and recovery, including resin and ligand types, conductivity, pH, gradient profiles, and the sequence of separation operations. The number of possible experimental conditions quickly becomes unmanageable. Although the range of suitable conditions can be narrowed based on experience, the time and cost of the work remain high even when using high-throughput laboratory automation. In contrast, chromatography modeling using inexpensive, parallelized computer hardware can provide expert knowledge, predicting conditions that achieve high purity and efficient recovery. The prediction of suitable conditions in silico reduces the number of empirical tests required and provides in-depth process understanding, which is recommended by regulatory authorities. In this article, we discuss the benefits and specific challenges of chromatography modeling. We describe the experimental characterization of chromatography devices and settings prior to modeling, such as the determination of column porosity. We also consider the challenges that must be overcome when models are set up and calibrated, including the cross-validation and verification of data-driven and hybrid (combined data-driven and mechanistic) models. This review will therefore support researchers intending to establish a chromatography modeling workflow in their laboratory.},
  language  = {en}
}
@article{BandlitzNakhoulKotliar2022,
  author    = {Bandlitz, Stefan and Nakhoul, Makram and Kotliar, Konstantin},
  title     = {Daily variations of corneal white-to-white diameter measured with different methods},
  series = {Clinical and experimental optometry},
  journal   = {Clinical and experimental optometry},
  number    = {14},
  publisher = {Taylor \& Francis},
  address   = {London},
  issn      = {0816-4622},
  doi       = {10.2147/OPTO.S360651},
  pages     = {173 -- 181},
  year      = {2022},
  abstract  = {Purpose: A precise determination of the corneal diameter is essential for the diagnosis of various ocular diseases, cataract and refractive surgery as well as for the selection and fitting of contact lenses. The aim of this study was to investigate the agreement between two automatic and one manual method for corneal diameter determination and to evaluate possible diurnal variations in corneal diameter. Patients and Methods: Horizontal white-to-white corneal diameter of 20 volunteers was measured at three different fixed times of a day with three methods: Scheimpflug method (Pentacam HR, Oculus), placido based topography (Keratograph 5M, Oculus) and manual method using an image analysis software at a slitlamp (BQ900, Haag-Streit). Results: The two-factorial analysis of variance could not show a significant effect of the different instruments (p = 0.117), the different time points (p = 0.506) and the interaction between instrument and time point (p = 0.182). Very good repeatability (intraclass correlation coefficient ICC, quartile coefficient of dispersion QCD) was found for all three devices. However, manual slitlamp measurements showed a higher QCD than the automatic measurements with the Keratograph 5M and the Pentacam HR at all measurement times. Conclusion: The manual and automated methods used in the study to determine corneal diameter showed good agreement and repeatability. No significant diurnal variations of corneal diameter were observed during the period of time studied.},
  language  = {en}
}
@masterthesis{Nelles2022,
  type      = {Bachelor Thesis},
  author    = {Nelles, Charlene},
  title     = {Brain Hack},
  publisher = {FH Aachen},
  address   = {Aachen},
  pages     = {77 Seiten},
  year      = {2022},
  abstract  = {Protagonistin des Films ist Cassandra Becker, eine 25-j{\"a}hrige Informatikstudentin und Mitglied der Hackerorganisation PFABW (Progress For a Better World). Sie hat es sich zum Ziel gesetzt, die Welt zu einem besseren Ort zu machen. Sie legt sich allerdings mit den falschen Leuten an und wird f{\"u}r die Verbreitung eines zerst{\"o}rerischen Computervirus verantwortlich gemacht, der gesundheitliche Folgen f{\"u}r den Menschen mit sich bringt. Sie und ihr bester Freund Jake Fischer haben bei einem PFABW-Mitglied Zuflucht gefunden. Dort versuchen sie gemeinsam herauszufinden, was es mit dem mysteri{\"o}sen Virus auf sich hat.},
  language  = {de}
}