@article{WerkhausenAlbrachtCroninetal.2018,
  author    = {Werkhausen, Amelie and Albracht, Kirsten and Cronin, Neil J and Paulsen, G{\o}ran and Bojsen-M{\o}ller, Jens and Seynnes, Olivier R},
  title     = {Effect of training-induced changes in achilles tendon stiffness on muscle-tendon behavior during landing},
  series = {Frontiers in physiology},
  journal   = {Frontiers in physiology},
  number    = {9},
  publisher = {Frontiers Research Foundation},
  address   = {Lausanne},
  issn      = {1664-042X},
  doi       = {10.3389/fphys.2018.00794},
  pages     = {11 Seiten},
  year      = {2018},
  abstract  = {During rapid deceleration of the body, tendons buffer part of the elongation of the muscle-tendon unit (MTU), enabling safe energy dissipation via eccentric muscle contraction. Yet, the influence of changes in tendon stiffness within the physiological range upon these lengthening contractions is unknown. This study aimed to examine the effect of training-induced stiffening of the Achilles tendon on triceps surae muscle-tendon behavior during a landing task. Twenty-one male subjects were assigned to either a 10-week resistance-training program consisting of single-leg isometric plantarflexion (n = 11) or to a non-training control group (n = 10). Before and after the training period, plantarflexion force, peak Achilles tendon strain and stiffness were measured during isometric contractions, using a combination of dynamometry, ultrasound and kinematics data. Additionally, testing included a step-landing task, during which joint mechanics and lengths of gastrocnemius and soleus fascicles, Achilles tendon, and MTU were determined using synchronized ultrasound, kinematics and kinetics data collection. After training, plantarflexion strength and Achilles tendon stiffness increased (15 and 18\%, respectively), and tendon strain during landing remained similar. Likewise, lengthening and negative work produced by the gastrocnemius MTU did not change detectably. However, in the training group, gastrocnemius fascicle length was offset (8\%) to a longer length at touch down and, surprisingly, fascicle lengthening and velocity were reduced by 27 and 21\%, respectively. These changes were not observed for soleus fascicles when accounting for variation in task execution between tests. These results indicate that a training-induced increase in tendon stiffness does not noticeably affect the buffering action of the tendon when the MTU is rapidly stretched. Reductions in gastrocnemius fascicle lengthening and lengthening velocity during landing occurred independently from tendon strain. Future studies are required to provide insight into the mechanisms underpinning these observations and their influence on energy dissipation.},
  language  = {en}
}
@article{HaegerJolmesOyenetal.2024,
  author    = {Haeger, Gerrit and Jolmes, Tristan and Oyen, Sven and Jaeger, Karl-Erich and Bongaerts, Johannes and Sch{\"o}rken, Ulrich and Siegert, Petra},
  title     = {Novel recombinant aminoacylase from Paraburkholderia monticola capable of N-acyl-amino acid synthesis},
  series = {Applied Microbiology and Biotechnology},
  journal   = {Applied Microbiology and Biotechnology},
  number    = {108},
  publisher = {Springer},
  address   = {Berlin},
  issn      = {1432-0614},
  doi       = {10.1007/s00253-023-12868-8},
  pages     = {14 Seiten},
  year      = {2024},
  abstract  = {N-Acyl-amino acids can act as mild biobased surfactants, which are used, e.g., in baby shampoos. However, their chemical synthesis needs acyl chlorides and does not meet sustainability criteria. Thus, the identification of biocatalysts to develop greener synthesis routes is desirable. We describe a novel aminoacylase from Paraburkholderia monticola DSM 100849 (PmAcy) which was identified, cloned, and evaluated for its N-acyl-amino acid synthesis potential. Soluble protein was obtained by expression in lactose autoinduction medium and co-expression of molecular chaperones GroEL/S. Strep-tag affinity purification enriched the enzyme 16-fold and yielded 15 mg pure enzyme from 100 mL of culture. Biochemical characterization revealed that PmAcy possesses beneficial traits for industrial application like high temperature and pH-stability. A heat activation of PmAcy was observed upon incubation at temperatures up to 80 °C. Hydrolytic activity of PmAcy was detected with several N-acyl-amino acids as substrates and exhibited the highest conversion rate of 773 U/mg with N-lauroyl-L-alanine at 75 °C. The enzyme preferred long-chain acyl-amino-acids and displayed hardly any activity with acetyl-amino acids. PmAcy was also capable of N-acyl-amino acid synthesis with good conversion rates. The best synthesis results were obtained with the cationic L-amino acids L-arginine and L-lysine as well as with L-leucine and L-phenylalanine. Exemplarily, L-phenylalanine was acylated with fatty acids of chain lengths from C8 to C18 with conversion rates of up to 75\%. N-lauroyl-L-phenylalanine was purified by precipitation, and the structure of the reaction product was verified by LC-MS and NMR.},
  language  = {en}
}
@article{YangKriechbaumerAlbrachtetal.2014,
  author    = {Yang, Peng-Fei and Kriechbaumer, Andreas and Albracht, Kirsten and Sanno, Maximilian and Ganse, Bergita and Koy, Timmo and Shang, Peng and br{\"u}ggemann, Gert-Peter and M{\"u}ller, Lars Peter and Rittweger, J{\"o}rn},
  title     = {A novel optical approach for assessing in vivo bone segment deformation and its application in muscle-bone relationship studies in humans},
  series = {Journal of Orthopaedic Translation},
  volume    = {2},
  journal   = {Journal of Orthopaedic Translation},
  number    = {4},
  publisher = {Elsevier},
  address   = {Singapore},
  issn      = {2214-0328},
  doi       = {10.1016/j.jot.2014.07.078},
  pages     = {238 -- 238},
  year      = {2014},
  language  = {en}
}
@unpublished{RingersBialonskiSolovevetal.2021,
  author    = {Ringers, Christa and Bialonski, Stephan and Solovev, Anton and Hansen, Jan N. and Ege, Mert and Friedrich, Benjamin M. and Jurisch-Yaksi, Nathalie},
  title     = {Preprint: Local synchronization of cilia and tissue-scale cilia alignment are sufficient for global metachronal waves},
  series = {bioRxiv},
  journal   = {bioRxiv},
  doi       = {10.1101/2021.11.23.469646},
  pages     = {19 Seiten},
  year      = {2021},
  abstract  = {Motile cilia are hair-like cell extensions present in multiple organs of the body. How cilia coordinate their regular beat in multiciliated epithelia to move fluids remains insufficiently understood, particularly due to lack of rigorous quantification. We combine here experiments, novel analysis tools, and theory to address this knowledge gap. We investigate collective dynamics of cilia in the zebrafish nose, due to its conserved properties with other ciliated tissues and its superior accessibility for non-invasive imaging. We revealed that cilia are synchronized only locally and that the size of local synchronization domains increases with the viscosity of the surrounding medium. Despite the fact that synchronization is local only, we observed global patterns of traveling metachronal waves across the multiciliated epithelium. Intriguingly, these global wave direction patterns are conserved across individual fish, but different for left and right nose, unveiling a chiral asymmetry of metachronal coordination. To understand the implications of synchronization for fluid pumping, we used a computational model of a regular array of cilia. We found that local metachronal synchronization prevents steric collisions and improves fluid pumping in dense cilia carpets, but hardly affects the direction of fluid flow. In conclusion, we show that local synchronization together with tissue-scale cilia alignment are sufficient to generate metachronal wave patterns in multiciliated epithelia, which enhance their physiological function of fluid pumping.},
  language  = {en}
}
@article{vonHaefenKrautwaldStolleetal.2022,
  author    = {von H{\"a}fen, Hajo and Krautwald, Clemens and Stolle, Jacob and Bung, Daniel Bernhard and Goseberg, Nils},
  title     = {Overland flow of broken solitary waves over a two-dimensional coastal plane},
  series = {Coastal Engineering},
  volume    = {175},
  journal   = {Coastal Engineering},
  number    = {August},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1872-7379},
  doi       = {10.1016/j.coastaleng.2022.104125},
  pages     = {14 Seiten},
  year      = {2022},
  abstract  = {Landslides, rock falls or related subaerial and subaqueous mass slides can generate devastating impulse waves in adjacent waterbodies. Such waves can occur in lakes and fjords, or due to glacier calving in bays or at steep ocean coastlines. Infrastructure and residential houses along coastlines of those waterbodies are often situated on low elevation terrain, and are potentially at risk from inundation. Impulse waves, running up a uniform slope and generating an overland flow over an initially dry adjacent horizontal plane, represent a frequently found scenario, which needs to be better understood for disaster planning and mitigation. This study presents a novel set of large-scale flume test focusing on solitary waves propagating over a 1:14.5 slope and breaking onto a horizontal section. Examining the characteristics of overland flow, this study gives, for the first time, insight into the fundamental process of overland flow of a broken solitary wave: its shape and celerity, as well as its momentum when wave breaking has taken place beforehand.},
  language  = {en}
}
@misc{OPUS4-10951,
  title     = {Richtlinie zur Durchf{\"u}hrung von Sonderveranstaltungen in den Geb{\"a}uden und Liegenschaften der FH Aachen (Veranstaltungsrichtlinie) : vom 20. November 2019},
  organization    = {FH Aachen},
  pages     = {21 Seiten},
  year      = {2019},
  language  = {de}
}
@misc{OPUS4-10952,
  title     = {Richtlinie zur Durchf{\"u}hrung von Sonderveranstaltungen in den Geb{\"a}uden und Liegenschaften der FH Aachen (Veranstaltungsrichtlinie) : vom 20. November 2019 Anlage 1 aktualisiert am 22. Januar 2020},
  organization    = {FH Aachen},
  pages     = {21 Seiten},
  year      = {2019},
  language  = {de}
}
@misc{OPUS4-10953,
  title     = {Richtlinie f{\"u}r die Besch{\"a}ftigung und Verg{\"u}tung studentischer und wissenschaftlicher Hilfskr{\"a}fte an der Fachhochschule Aachen : vom 20. November 2019},
  organization    = {FH Aachen},
  pages     = {6 Seiten},
  year      = {2019},
  language  = {de}
}
@misc{OPUS4-10954,
  title     = {Richtlinie f{\"u}r die Besch{\"a}ftigung und Verg{\"u}tung studentischer und wissenschaftlicher Hilfskr{\"a}fte an der Fachhochschule Aachen : vom 20. November 2019 aktualisiert am 24. November 2022},
  organization    = {FH Aachen},
  pages     = {6 Seiten},
  year      = {2019},
  language  = {de}
}
@misc{OPUS4-10955,
  title     = {Gleichstellungsquoten der FH Aachen f{\"u}r die Jahre 2019 -2021 : vom 20. November 2019},
  organization    = {FH Aachen},
  pages     = {2 Seiten},
  year      = {2019},
  language  = {de}
}
@misc{OPUS4-10956,
  title     = {Ordnung zur Aufhebung der Pr{\"u}fungsordnungen f{\"u}r den Masterstudiengang „Nuclear Applications" vom 13. Februar 2004 (FH-Mitteilung Nr. 5/2004) und vom 25. Februar 2010 (FH-Mitteilung Nr. 15/2010) in den Fassungen der Bekanntmachung der {\"A}nderungsordnungen vom 6. November 2012 (FH-Mitteilung Nr. 120/2012), 18. Juni 2014 (FH- Mitteilung Nr. 72/2014) und vom 15. Juni 2015 (FH-Mitteilung Nr. 28/2015) : vom 29. November 2019},
  organization    = {FH Aachen},
  pages     = {3 Seiten},
  year      = {2019},
  language  = {de}
}
@misc{OPUS4-10957,
  title     = {5. Ordnung zur {\"A}nderung der Pr{\"u}fungsordnung f{\"u}r die Bachelorstudieng{\"a}nge „Betriebswirtschaft Praxis Plus" und „Betriebswirtschaft Praxis Plus (Teilzeit)" mit dem Studienabschluss „Bachelor of Science" am Fachbereich Wirtschaftswissenschaften der Fachhochschule Aachen (PO - BWL Praxis Plus) : vom 29. November 2019},
  organization    = {FH Aachen},
  pages     = {2 Seiten},
  year      = {2019},
  language  = {de}
}
@misc{OPUS4-10958,
  title     = {Pr{\"u}fungsordnung f{\"u}r die Bachelorstudieng{\"a}nge „Betriebswirtschaft Praxis Plus" und „Betriebswirtschaft Praxis Plus (Teilzeit)" mit dem Studienabschluss „Bachelor of Science" am Fachbereich Wirtschaftswissenschaften der Fachhochschule Aachen (PO-BWL Praxis Plus) : vom 14. Januar 2014 - FH-Mitteilung Nr. 2/2014 in der Fassung der Bekanntmachung der {\"A}nderungsordnung vom 29. November 2019 - FH-Mitteilung Nr. 128/2019 (Nichtamtliche lesbare Fassung | Studienbeginn ab WS 2019/20)},
  organization    = {FH Aachen},
  pages     = {11 Seiten},
  year      = {2019},
  language  = {de}
}
@misc{OPUS4-10959,
  title     = {2. {\"A}nderung der Richtlinie des Rektorats der FH Aachen f{\"u}r die Vergabe von Lehrveranstaltungspr{\"a}mien : vom 13. Dezember 2019},
  organization    = {FH Aachen},
  pages     = {2 Seiten},
  year      = {2019},
  language  = {de}
}
@misc{OPUS4-10960,
  title     = {Richtlinie des Rektorats der FH Aachen f{\"u}r die Vergabe von Lehrveranstaltungspr{\"a}mien : vom 16. Juli 2012 - FH-Mitteilung Nr. 68/2012 in der Fassung der Bekanntmachung der {\"A}nderung vom 13. Dezember 2019 - FH-Mitteilung Nr. 130/2019 (Nichtamtliche lesbare Fassung)},
  organization    = {FH Aachen},
  pages     = {3 Seiten},
  year      = {2019},
  language  = {de}
}
@misc{OPUS4-10961,
  title     = {Pr{\"u}fungsordnung f{\"u}r den Masterstudiengang Nuclear Applications im Fachbereich Chemie und Biotechnologie an der Fachhochschule Aachen : vom 17. Dezember 2019},
  organization    = {FH Aachen},
  pages     = {7 Seiten},
  year      = {2019},
  language  = {de}
}
@misc{OPUS4-10962,
  title     = {Ordnung zur Aufhebung der Pr{\"u}fungsordnung f{\"u}r den Masterstudiengang „Information Systems Engineering" vom 22. Januar 2010 (FH-Mitteilung Nr. 5/2010), zuletzt ge{\"a}ndert durch {\"A}nderungsordnung vom 4. Februar 2013 (FH-Mitteilung Nr. 6/2013) : vom 20. Dezember 2019},
  organization    = {FH Aachen},
  pages     = {3 Seiten},
  year      = {2019},
  language  = {de}
}
@misc{OPUS4-10963,
  title     = {Ordnung zur Aufhebung der Pr{\"u}fungsordnung f{\"u}r den Masterstudiengang „Elektrotechnik" (zuvor „Nachrichtentechnik" und „Elektrotechnik und Informationstechnik") vom 22. Januar 2010 (FH-Mitteilung Nr. 7/2010), zuletzt ge{\"a}ndert durch {\"A}nderungsordnung vom 25. April 2016 (FH-Mitteilung Nr. 31/2016) : vom 20. Dezember 2019},
  organization    = {FH Aachen},
  pages     = {3 Seiten},
  year      = {2019},
  language  = {de}
}
@misc{OPUS4-10964,
  title     = {Ordnung zur Aufhebung der Pr{\"u}fungsordnung f{\"u}r die Masterstudieng{\"a}nge „Energiewirtschaft \& Informatik" (3 Semester) und „Energiewirtschaft \& Informatik" (4 Semester) vom 4. Mai 2016 (FH-Mitteilung Nr. 59/2016) Fachbereich Energietechnik Fachbereich Medizintechnik und Technomathematik an der Fachhochschule Aachen : vom 16. Januar 2020},
  organization    = {FH Aachen},
  pages     = {3 Seiten},
  year      = {2020},
  language  = {de}
}
@misc{OPUS4-10965,
  title     = {Verwaltungs- und Benutzungsordnung des Solar-Instituts J{\"u}lich (SIJ) : vom 27. Januar 2020},
  organization    = {FH Aachen},
  pages     = {5 Seiten},
  year      = {2020},
  language  = {de}
}