@inproceedings{SimsekKrauseEngelmann2024, author = {Simsek, Beril and Krause, Hans-Joachim and Engelmann, Ulrich M.}, title = {Magnetic biosensing with magnetic nanoparticles: Simulative approach to predict signal intensity in frequency mixing magnetic detection}, series = {YRA MedTech Symposium (2024)}, booktitle = {YRA MedTech Symposium (2024)}, editor = {Digel, Ilya and Staat, Manfred and Trzewik, J{\"u}rgen and Sielemann, Stefanie and Erni, Daniel and Zylka, Waldemar}, publisher = {Universit{\"a}t Duisburg-Essen}, address = {Duisburg}, organization = {MedTech Symposium}, isbn = {978-3-940402-65-3}, doi = {10.17185/duepublico/81475}, pages = {27 -- 28}, year = {2024}, abstract = {Magnetic nanoparticles (MNP) are investigated with great interest for biomedical applications in diagnostics (e.g. imaging: magnetic particle imaging (MPI)), therapeutics (e.g. hyperthermia: magnetic fluid hyperthermia (MFH)) and multi-purpose biosensing (e.g. magnetic immunoassays (MIA)). What all of these applications have in common is that they are based on the unique magnetic relaxation mechanisms of MNP in an alternating magnetic field (AMF). While MFH and MPI are currently the most prominent examples of biomedical applications, here we present results on the relatively new biosensing application of frequency mixing magnetic detection (FMMD) from a simulation perspective. In general, we ask how the key parameters of MNP (core size and magnetic anisotropy) affect the FMMD signal: by varying the core size, we investigate the effect of the magnetic volume per MNP; and by changing the effective magnetic anisotropy, we study the MNPs' flexibility to leave its preferred magnetization direction. From this, we predict the most effective combination of MNP core size and magnetic anisotropy for maximum signal generation.}, language = {en} } @article{AyalaHarrisKleefeld2024, author = {Ayala, Rafael Ceja and Harris, Isaac and Kleefeld, Andreas}, title = {Direct sampling method via Landweber iteration for an absorbing scatterer with a conductive boundary}, series = {Inverse Problems and Imaging}, volume = {18}, journal = {Inverse Problems and Imaging}, number = {3}, publisher = {AIMS}, address = {Springfield}, issn = {1930-8337}, doi = {10.3934/ipi.2023051}, pages = {708 -- 729}, year = {2024}, abstract = {In this paper, we consider the inverse shape problem of recovering isotropic scatterers with a conductive boundary condition. Here, we assume that the measured far-field data is known at a fixed wave number. Motivated by recent work, we study a new direct sampling indicator based on the Landweber iteration and the factorization method. Therefore, we prove the connection between these reconstruction methods. The method studied here falls under the category of qualitative reconstruction methods where an imaging function is used to recover the absorbing scatterer. We prove stability of our new imaging function as well as derive a discrepancy principle for recovering the regularization parameter. The theoretical results are verified with numerical examples to show how the reconstruction performs by the new Landweber direct sampling method.}, language = {en} } @article{HaegerJolmesOyenetal.2024, author = {Haeger, Gerrit and Jolmes, Tristan and Oyen, Sven and Jaeger, Karl-Erich and Bongaerts, Johannes and Sch{\"o}rken, Ulrich and Siegert, Petra}, title = {Novel recombinant aminoacylase from Paraburkholderia monticola capable of N-acyl-amino acid synthesis}, series = {Applied Microbiology and Biotechnology}, journal = {Applied Microbiology and Biotechnology}, number = {108}, publisher = {Springer}, address = {Berlin}, issn = {1432-0614}, doi = {10.1007/s00253-023-12868-8}, pages = {14 Seiten}, year = {2024}, abstract = {N-Acyl-amino acids can act as mild biobased surfactants, which are used, e.g., in baby shampoos. However, their chemical synthesis needs acyl chlorides and does not meet sustainability criteria. Thus, the identification of biocatalysts to develop greener synthesis routes is desirable. We describe a novel aminoacylase from Paraburkholderia monticola DSM 100849 (PmAcy) which was identified, cloned, and evaluated for its N-acyl-amino acid synthesis potential. Soluble protein was obtained by expression in lactose autoinduction medium and co-expression of molecular chaperones GroEL/S. Strep-tag affinity purification enriched the enzyme 16-fold and yielded 15 mg pure enzyme from 100 mL of culture. Biochemical characterization revealed that PmAcy possesses beneficial traits for industrial application like high temperature and pH-stability. A heat activation of PmAcy was observed upon incubation at temperatures up to 80 °C. Hydrolytic activity of PmAcy was detected with several N-acyl-amino acids as substrates and exhibited the highest conversion rate of 773 U/mg with N-lauroyl-L-alanine at 75 °C. The enzyme preferred long-chain acyl-amino-acids and displayed hardly any activity with acetyl-amino acids. PmAcy was also capable of N-acyl-amino acid synthesis with good conversion rates. The best synthesis results were obtained with the cationic L-amino acids L-arginine and L-lysine as well as with L-leucine and L-phenylalanine. Exemplarily, L-phenylalanine was acylated with fatty acids of chain lengths from C8 to C18 with conversion rates of up to 75\%. N-lauroyl-L-phenylalanine was purified by precipitation, and the structure of the reaction product was verified by LC-MS and NMR.}, language = {en} } @article{TixMollKrafftetal.2024, author = {Tix, Julian and Moll, Fabian and Krafft, Simone and Betsch, Matthias and Tippk{\"o}tter, Nils}, title = {Hydrogen production from enzymatic pretreated organic waste with thermotoga neapolitana}, series = {Energies}, volume = {17}, journal = {Energies}, number = {12}, publisher = {MDPI}, address = {Basel}, issn = {1996-1073}, doi = {10.3390/en17122938}, pages = {20 Seiten}, year = {2024}, abstract = {Biomass from various types of organic waste was tested for possible use in hydrogen production. The composition consisted of lignified samples, green waste, and kitchen scraps such as fruit and vegetable peels and leftover food. For this purpose, the enzymatic pretreatment of organic waste with a combination of five different hydrolytic enzymes (cellulase, amylase, glucoamylase, pectinase and xylase) was investigated to determine its ability to produce hydrogen (H2) with the hydrolyzate produced here. In course, the anaerobic rod-shaped bacterium T. neapolitana was used for H2 production. First, the enzymes were investigated using different substrates in preliminary experiments. Subsequently, hydrolyses were carried out using different types of organic waste. In the hydrolysis carried out here for 48 h, an increase in glucose concentration of 481\% was measured for waste loads containing starch, corresponding to a glucose concentration at the end of hydrolysis of 7.5 g·L-1. In the subsequent set fermentation in serum bottles, a H2 yield of 1.26 mmol H2 was obtained in the overhead space when Terrific Broth Medium with glucose and yeast extract (TBGY medium) was used. When hydrolyzed organic waste was used, even a H2 yield of 1.37 mmol could be achieved in the overhead space. In addition, a dedicated reactor system for the anaerobic fermentation of T. neapolitana to produce H2 was developed. The bioreactor developed here can ferment anaerobically with a very low loss of produced gas. Here, after 24 h, a hydrogen concentration of 83\% could be measured in the overhead space.}, language = {en} } @unpublished{GriegerMehrkanoonBialonski2024, author = {Grieger, Niklas and Mehrkanoon, Siamak and Bialonski, Stephan}, title = {Preprint: Data-efficient sleep staging with synthetic time series pretraining}, series = {arXiv}, journal = {arXiv}, pages = {10 Seiten}, year = {2024}, abstract = {Analyzing electroencephalographic (EEG) time series can be challenging, especially with deep neural networks, due to the large variability among human subjects and often small datasets. To address these challenges, various strategies, such as self-supervised learning, have been suggested, but they typically rely on extensive empirical datasets. Inspired by recent advances in computer vision, we propose a pretraining task termed "frequency pretraining" to pretrain a neural network for sleep staging by predicting the frequency content of randomly generated synthetic time series. Our experiments demonstrate that our method surpasses fully supervised learning in scenarios with limited data and few subjects, and matches its performance in regimes with many subjects. Furthermore, our results underline the relevance of frequency information for sleep stage scoring, while also demonstrating that deep neural networks utilize information beyond frequencies to enhance sleep staging performance, which is consistent with previous research. We anticipate that our approach will be advantageous across a broad spectrum of applications where EEG data is limited or derived from a small number of subjects, including the domain of brain-computer interfaces.}, language = {en} } @inproceedings{WittigRuettersBragard2024, author = {Wittig, M. and R{\"u}tters, Ren{\´e} and Bragard, Michael}, title = {Application of RL in control systems using the example of a rotatory inverted pendulum}, series = {Tagungsband AALE 2024 : Fit f{\"u}r die Zukunft: praktische L{\"o}sungen f{\"u}r die industrielle Automation}, booktitle = {Tagungsband AALE 2024 : Fit f{\"u}r die Zukunft: praktische L{\"o}sungen f{\"u}r die industrielle Automation}, editor = {Reiff-Stephan, J{\"o}rg and J{\"a}kel, Jens and Schwarz, Andr{\´e}}, publisher = {le-tex publishing services GmbH}, address = {Leipzig}, isbn = {978-3-910103-02-3}, doi = {10.33968/2024.53}, pages = {241 -- 248}, year = {2024}, abstract = {In this paper, the use of reinforcement learning (RL) in control systems is investigated using a rotatory inverted pendulum as an example. The control behavior of an RL controller is compared to that of traditional LQR and MPC controllers. This is done by evaluating their behavior under optimal conditions, their disturbance behavior, their robustness and their development process. All the investigated controllers are developed using MATLAB and the Simulink simulation environment and later deployed to a real pendulum model powered by a Raspberry Pi. The RL algorithm used is Proximal Policy Optimization (PPO). The LQR controller exhibits an easy development process, an average to good control behavior and average to good robustness. A linear MPC controller could show excellent results under optimal operating conditions. However, when subjected to disturbances or deviations from the equilibrium point, it showed poor performance and sometimes instable behavior. Employing a nonlinear MPC Controller in real time was not possible due to the high computational effort involved. The RL controller exhibits by far the most versatile and robust control behavior. When operated in the simulation environment, it achieved a high control accuracy. When employed in the real system, however, it only shows average accuracy and a significantly greater performance loss compared to the simulation than the traditional controllers. With MATLAB, it is not yet possible to directly post-train the RL controller on the Raspberry Pi, which is an obstacle to the practical application of RL in a prototyping or teaching setting. Nevertheless, RL in general proves to be a flexible and powerful control method, which is well suited for complex or nonlinear systems where traditional controllers struggle.}, language = {en} } @inproceedings{KramerBragardRitzetal.2024, author = {Kramer, Pia and Bragard, Michael and Ritz, Thomas and Ferfer, Ute and Schiffers, Tim}, title = {Visualizing, Enhancing and Predicting Students' Success through ECTS Monitoring}, series = {2024 IEEE Global Engineering Education Conference (EDUCON)}, booktitle = {2024 IEEE Global Engineering Education Conference (EDUCON)}, publisher = {IEEE}, address = {New York, NY}, issn = {2165-9559}, doi = {10.1109/EDUCON60312.2024.10578652}, pages = {5 Seiten}, year = {2024}, abstract = {This paper serves as an introduction to the ECTS monitoring system and its potential applications in higher education. It also emphasizes the potential for ECTS monitoring to become a proactive system, supporting students by predicting academic success and identifying groups of potential dropouts for tailored support services. The use of the nearest neighbor analysis is suggested for improving data analysis and prediction accuracy.}, language = {en} } @book{DrummScheuermannWeidner2024, author = {Drumm, Christian and Scheuermann, Bernd and Weidner, Stefan}, title = {Introduction to SAP S/4HANA® : The official companion book based on model company Global Bike-for learning, teaching, and training}, publisher = {Espresso Tutorials}, address = {Gleichen}, isbn = {9783960122685}, pages = {619 Seiten}, year = {2024}, abstract = {This easy-to-understand introduction to SAP S/4HANA guides you through the central processes in sales, purchasing and procurement, finance, production, and warehouse management using the model company Global Bike. Familiarize yourself with the basics of business administration, the relevant organizational data, master data, and transactional data, as well as a selection of core business processes in SAP. Using practical examples and tutorials, you will soon become an SAP S/4HANA professional! Tutorials and exercises for beginners, advanced users, and experts make it easy for you to practice your new knowledge. The prerequisite for this book is access to an SAP S/4HANA client with Global Bike version 4.1. - Business fundamentals and processes in the SAP system - Sales, purchasing and procurement, production, finance, and warehouse management - Tutorials at different qualification levels, exercises, and recap of case studies - Includes extensive download material for students, lecturers, and professors}, language = {en} } @inproceedings{SherelkhanAlibekova2024, author = {Sherelkhan, Dinara and Alibekova, Alina}, title = {EEM spectroscopy characterization of humic substances of biomedical importance}, series = {YRA MedTech Symposium (2024)}, booktitle = {YRA MedTech Symposium (2024)}, editor = {Digel, Ilya and Staat, Manfred and Trzewik, J{\"u}rgen and Sielemann, Stefanie and Erni, Daniel and Zylka, Waldemar}, publisher = {Universit{\"a}t Duisburg-Essen}, address = {Duisburg}, organization = {MedTech Symposium}, isbn = {978-3-940402-65-3}, doi = {10.17185/duepublico/81475}, pages = {31 -- 32}, year = {2024}, abstract = {Humic substances possess distinctive chemical features enabling their use in many advanced applications, including biomedical fields. No chemicals in nature have the same combination of specific chemical and biological properties as humic substances. Traditional medicine and modern research have demonstrated that humic substances from different sources possess immunomodulatory and anti-inflammatory properties, which makes them suitable for the prevention and treatment of chronic dermatoses, allergic rhinitis, atopic dermatitis, and other conditions characterized by inflammatory and allergic responses [1-4]. The use of humic compounds as agentswith antifungal and antiviral properties shows great potential [5-7].}, language = {en} } @techreport{Drescher2024, type = {Working Paper}, author = {Drescher, Hans Paul}, title = {Critical review of the 1. Stokes' problem and consequences for mixed turbulent/laminar flow}, pages = {27 Seiten}, year = {2024}, abstract = {The "1. Stokes' problem", the "suddenly accelerated flat wall", is the oldest application of the Navier-Stokes equations. Stokes' solution of the "problem" does not comply with the mathematical theorem of Cauchy and Kowalewskaya on the "Uniqueness and Existence" of solutions of partial differential equations and violates the physical theorem of minimum entropy production/dissipation of the Thermodynamics of Irreversible Processes. The result includes very high local shear stresses and dissipation rates. That is of special interest for the theory of turbulent and mixed turbulent/laminar flow. A textbook solution of the "1. Stokes Problem" is the Couette flow, which has a constant sheer stress along a linear profile. A consequence is that the Navier-Stokes equations do not describe any S-shaped part of a turbulent profile found in any turbulent Couette experiment. The paper surveys arguments referring to that statement, concerning the history of >150 years. Contrary to this there is always a Navier-Stokes solution near the wall, observed by a linear part of the Couette profile. There a turbulent description (e.g. by the logarithmic law-of-the-wall) fails completely. That is explained by the minimum dissipation requirement together with the Couette feature τ = const. The local co-existence of a turbulent zone and a laminar zone near the wall is stable and observed also at high Reynolds-Numbers.}, language = {en} } @article{SchoppRohrbachLangeretal.2024, author = {Schopp, Christoph and Rohrbach, Felix and Langer, Luc and Heuermann, Holger}, title = {Detection of welding wire length by active S11 measurement}, series = {IEEE Transactions on Plasma Science}, journal = {IEEE Transactions on Plasma Science}, number = {Early Access}, publisher = {IEEE}, issn = {0093-3813 (Print)}, doi = {10.1109/TPS.2024.3356659}, pages = {1 -- 6}, year = {2024}, abstract = {A novel method to determine the extruded length of a metallic wire for a directed energy deposition (DED) process using a microwave (MW) plasma jet with a straight-through wire feed is presented. The method is based on the relative comparison of the measured frequency response obtained by the large-signal scattering parameter (Hot-S) technique. In the practical working range, repeatability of less than 6\% for a nonactive plasma and 9\% for the active plasma state is found. Measurements are conducted with a focus on a simple solution to decrease the processing time and reduce the integration time of the process into the existing hardware. It is shown that monitoring a single frequency for magnitude and phase changes is sufficient to achieve good accuracy. A combination of different measurement values to determine the length is possible. The applicability to different diameter of the same material is shown as well as a contact detection of the wire and metallic substrate.}, language = {en} } @article{PieronekKleefeld2024, author = {Pieronek, Lukas and Kleefeld, Andreas}, title = {On trajectories of complex-valued interior transmission eigenvalues}, series = {Inverse problems and imaging : IPI}, volume = {18}, journal = {Inverse problems and imaging : IPI}, number = {2}, publisher = {AIMS}, address = {Springfield, Mo}, issn = {1930-8337 (Print)}, doi = {10.3934/ipi.2023041}, pages = {480 -- 516}, year = {2024}, abstract = {This paper investigates the interior transmission problem for homogeneous media via eigenvalue trajectories parameterized by the magnitude of the refractive index. In the case that the scatterer is the unit disk, we prove that there is a one-to-one correspondence between complex-valued interior transmission eigenvalue trajectories and Dirichlet eigenvalues of the Laplacian which turn out to be exactly the trajectorial limit points as the refractive index tends to infinity. For general simply-connected scatterers in two or three dimensions, a corresponding relation is still open, but further theoretical results and numerical studies indicate a similar connection.}, language = {en} } @article{AdelsMonakhova2024, author = {Adels, Klaudia and Monakhova, Yulia}, title = {Low-field NMR spectroscopic study of e-cigarettes: Is determination of only nicotine and organic carrier solvents possible?}, series = {Microchemical Journal}, volume = {203}, journal = {Microchemical Journal}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1095-9149}, doi = {10.1016/j.microc.2024.110859}, pages = {9 Seiten}, year = {2024}, abstract = {Electronic cigarettes (e-cigarettes) have become popular worldwide with the market growing exponentially in some countries. The absence of product standards and safety regulations requires urgent development of analytical methodologies for the holistic control of the growing diversity of such products. An approach based on low-field nuclear magnetic resonance (LF-NMR) at 80 MHz is presented for the simultaneous determination of key parameters: carrier solvents (vegetable glycerine (VG), propylene glycol (PG) and water), total nicotine as well as free-base nicotine fraction. Moreover, qualitative and quantitative determination of fourteen weak organic acids deliberately added to enhance sensory characteristics of e-cigarettes was possible. In most cases these parameters can be rapidly and conveniently determined without using any sample manipulation such as dilution, extraction or derivatization steps. The method was applied for 37 authentic e-cigarettes samples. In particular, eight different organic acids with the content up to 56 mg/mL were detected. Due to its simplicity, the method can be used in routine regulatory control as well as to study release behaviour of nicotine and other e-cigarettes constituents in different products.}, language = {en} } @incollection{GohTopcuMadabhushietal.2024, author = {Goh, Kheng Lim and Top{\c{c}}u, Murat and Madabhushi, Gopal S. P. and Staat, Manfred}, title = {Collagen fibril reinforcement in connective tissue extracellular matrices}, series = {Handbook of the extracellular matrix}, booktitle = {Handbook of the extracellular matrix}, editor = {Maia, Fatima Raquel Azevedo and Miguel Oliveira, J. and Reis, Rui L.}, publisher = {Springer Nature}, address = {Cham}, isbn = {978-3-031-56362-1 (Print)}, doi = {10.1007/978-3-031-56363-8_6}, pages = {89 -- 108}, year = {2024}, abstract = {The connective tissues such as tendons contain an extracellular matrix (ECM) comprising collagen fibrils scattered within the ground substance. These fibrils are instrumental in lending mechanical stability to tissues. Unfortunately, our understanding of how collagen fibrils reinforce the ECM remains limited, with no direct experimental evidence substantiating current theories. Earlier theoretical studies on collagen fibril reinforcement in the ECM have relied predominantly on the assumption of uniform cylindrical fibers, which is inadequate for modelling collagen fibrils, which possessed tapered ends. Recently, Top{\c{c}}u and colleagues published a paper in the International Journal of Solids and Structures, presenting a generalized shear-lag theory for the transfer of elastic stress between the matrix and fibers with tapered ends. This paper is a positive step towards comprehending the mechanics of the ECM and makes a valuable contribution to formulating a complete theory of collagen fibril reinforcement in the ECM.}, language = {en} } @article{SchopenShahEschetal.2024, author = {Schopen, Oliver and Shah, Neel and Esch, Thomas and Shabani, Bahman}, title = {Critical quantitative evaluation of integrated health management methods for fuel cell applications}, series = {International Journal of Hydrogen Energy}, volume = {70}, journal = {International Journal of Hydrogen Energy}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0360-3199}, doi = {10.1016/j.ijhydene.2024.05.156}, pages = {370 -- 388}, year = {2024}, abstract = {Online fault diagnostics is a crucial consideration for fuel cell systems, particularly in mobile applications, to limit downtime and degradation, and to increase lifetime. Guided by a critical literature review, in this paper an overview of Health management systems classified in a scheme is presented, introducing commonly utilised methods to diagnose FCs in various applications. In this novel scheme, various Health management system methods are summarised and structured to provide an overview of existing systems including their associated tools. These systems are classified into four categories mainly focused on model-based and non-model-based systems. The individual methods are critically discussed when used individually or combined aimed at further understanding their functionality and suitability in different applications. Additionally, a tool is introduced to evaluate methods from each category based on the scheme presented. This tool applies the technique of matrix evaluation utilising several key parameters to identify the most appropriate methods for a given application. Based on this evaluation, the most suitable methods for each specific application are combined to build an integrated Health management system.}, language = {en} } @inproceedings{Tepecik2024, author = {Tepecik, Atakan}, title = {AstroBioLab: Review of technical and bioanalytical approaches}, series = {YRA MedTech Symposium (2024)}, booktitle = {YRA MedTech Symposium (2024)}, editor = {Digel, Ilya and Staat, Manfred and Trzewik, J{\"u}rgen and Sielemann, Stefanie and Erni, Daniel and Zylka, Waldemar}, publisher = {Universit{\"a}t Duisburg-Essen}, address = {Duisburg}, organization = {MedTech Symposium}, isbn = {978-3-940402-65-3}, doi = {10.17185/duepublico/81475}, pages = {33 -- 34}, year = {2024}, abstract = {This study presents the concept of AstroBioLab, an autonomous astrobiological field laboratory tailored for the exploration of (sub)glacial habitats. AstroBioLab is an integral component of the TRIPLE (Technologies for Rapid Ice Penetration and subglacial Lake Exploration) DLR-funded project, aimed at advancing astrobiology research through the development and deployment of innovative technologies. AstroBioLab integrates diverse measurement techniques such as fluorescence microscopy, DNA sequencing and fluorescence spectrometry, while leveraging microfluidics for efficient sample delivery and preparation.}, language = {en} } @unpublished{SchmuellingGuetzlaffCzupalla2024, author = {Schm{\"u}lling, Max and G{\"u}tzlaff, Joel and Czupalla, Markus}, title = {A thermal simulation environment for moving objects on the lunar surface}, doi = {10.21203/rs.3.rs-3902363/v1}, pages = {12 Seiten}, year = {2024}, abstract = {This paper presents a thermal simulation environment for moving objects on the lunar surface. The goal of the thermal simulation environment is to enable the reliable prediction of the temperature development of a given object on the lunar surface by providing the respective heat fluxes for a mission on a given travel path. The user can import any object geometry and freely define the path that the object should travel. Using the path of the object, the relevant lunar surface geometry is imported from a digital elevation model. The relevant parts of the lunar surface are determined based on distance to the defined path. A thermal model of these surface sections is generated, consisting of a porous layer on top and a denser layer below. The object is moved across the lunar surface, and its inclination is adapted depending on the slope of the terrain below it. Finally, a transient thermal analysis of the object and its environment is performed at several positions on its path and the results are visualized. The paper introduces details on the thermal modeling of the lunar surface, as well as its verification. Furthermore, the structure of the created software is presented. The robustness of the environment is verified with the help of sensitivity studies and possible improvements are presented.}, language = {en} } @article{YoshinobuMiyamotoWagneretal.2024, author = {Yoshinobu, Tatsuo and Miyamoto, Ko-ichiro and Wagner, Torsten and Sch{\"o}ning, Michael Josef}, title = {Field-effect sensors combined with the scanned light pulse technique: from artificial olfactory images to chemical imaging technologies}, series = {Chemosensors}, volume = {12}, journal = {Chemosensors}, number = {2}, publisher = {MDPI}, address = {Basel}, issn = {2227-9040}, doi = {10.3390/chemosensors12020020}, pages = {Artikel 20}, year = {2024}, abstract = {The artificial olfactory image was proposed by Lundstr{\"o}m et al. in 1991 as a new strategy for an electronic nose system which generated a two-dimensional mapping to be interpreted as a fingerprint of the detected gas species. The potential distribution generated by the catalytic metals integrated into a semiconductor field-effect structure was read as a photocurrent signal generated by scanning light pulses. The impact of the proposed technology spread beyond gas sensing, inspiring the development of various imaging modalities based on the light addressing of field-effect structures to obtain spatial maps of pH distribution, ions, molecules, and impedance, and these modalities have been applied in both biological and non-biological systems. These light-addressing technologies have been further developed to realize the position control of a faradaic current on the electrode surface for localized electrochemical reactions and amperometric measurements, as well as the actuation of liquids in microfluidic devices.}, language = {en} } @article{BlockViebahnJungbluth2024, author = {Block, Simon and Viebahn, Peter and Jungbluth, Christian}, title = {Analysing direct air capture for enabling negative emissions in Germany: an assessment of the resource requirements and costs of a potential rollout in 2045}, series = {Frontiers in Climate}, volume = {6}, journal = {Frontiers in Climate}, publisher = {Frontiers}, address = {Lausanne}, issn = {2624-9553}, doi = {10.3389/fclim.2024.1353939}, pages = {18 Seiten}, year = {2024}, abstract = {Direct air capture (DAC) combined with subsequent storage (DACCS) is discussed as one promising carbon dioxide removal option. The aim of this paper is to analyse and comparatively classify the resource consumption (land use, renewable energy and water) and costs of possible DAC implementation pathways for Germany. The paths are based on a selected, existing climate neutrality scenario that requires the removal of 20 Mt of carbon dioxide (CO2) per year by DACCS from 2045. The analysis focuses on the so-called "low-temperature" DAC process, which might be more advantageous for Germany than the "high-temperature" one. In four case studies, we examine potential sites in northern, central and southern Germany, thereby using the most suitable renewable energies for electricity and heat generation. We show that the deployment of DAC results in large-scale land use and high energy needs. The land use in the range of 167-353 km2 results mainly from the area required for renewable energy generation. The total electrical energy demand of 14.4 TWh per year, of which 46\% is needed to operate heat pumps to supply the heat demand of the DAC process, corresponds to around 1.4\% of Germany's envisaged electricity demand in 2045. 20 Mt of water are provided yearly, corresponding to 40\% of the city of Cologne's water demand (1.1 million inhabitants). The capture of CO2 (DAC) incurs levelised costs of 125-138 EUR per tonne of CO2, whereby the provision of the required energy via photovoltaics in southern Germany represents the lowest value of the four case studies. This does not include the costs associated with balancing its volatility. Taking into account transporting the CO2 via pipeline to the port of Wilhelmshaven, followed by transporting and sequestering the CO2 in geological storage sites in the Norwegian North Sea (DACCS), the levelised costs increase to 161-176 EUR/tCO2. Due to the longer transport distances from southern and central Germany, a northern German site using wind turbines would be the most favourable.}, language = {en} } @inproceedings{KahraBreussKleefeldetal.2024, author = {Kahra, Marvin and Breuß, Michael and Kleefeld, Andreas and Welk, Martin}, title = {An Approach to Colour Morphological Supremum Formation Using the LogSumExp Approximation}, series = {Discrete Geometry and Mathematical Morphology}, booktitle = {Discrete Geometry and Mathematical Morphology}, editor = {Brunetti, Sara and Frosini, Andrea and Rinaldi, Simone}, publisher = {Springer}, address = {Cham}, isbn = {978-3-031-57793-2}, doi = {10.1007/978-3-031-57793-2_25}, pages = {325 -- 337}, year = {2024}, abstract = {Mathematical morphology is a part of image processing that has proven to be fruitful for numerous applications. Two main operations in mathematical morphology are dilation and erosion. These are based on the construction of a supremum or infimum with respect to an order over the tonal range in a certain section of the image. The tonal ordering can easily be realised in grey-scale morphology, and some morphological methods have been proposed for colour morphology. However, all of these have certain limitations. In this paper we present a novel approach to colour morphology extending upon previous work in the field based on the Loewner order. We propose to consider an approximation of the supremum by means of a log-sum exponentiation introduced by Maslov. We apply this to the embedding of an RGB image in a field of symmetric 2x2 matrices. In this way we obtain nearly isotropic matrices representing colours and the structural advantage of transitivity. In numerical experiments we highlight some remarkable properties of the proposed approach.}, language = {en} } @article{HafidiElHatkaSchmitzetal.2024, author = {Hafidi, Youssef and El Hatka, Hicham and Schmitz, Dominik and Krauss, Manuel and Pettrak, J{\"u}rgen and Biel, Markus and Ittobane, Najim}, title = {Sustainable soil additives for water and micronutrient supply: swelling and chelating properties of polyaspartic acid hydrogels utilizing newly developed crosslinkers}, series = {Gels}, volume = {10}, journal = {Gels}, number = {3}, publisher = {MDPI}, address = {Basel}, issn = {2310-2861}, doi = {10.3390/gels10030170}, pages = {Artikel 170}, year = {2024}, abstract = {Drought and water shortage are serious problems in many arid and semi-arid regions. This problem is getting worse and even continues in temperate climatic regions due to climate change. To address this problem, the use of biodegradable hydrogels is increasingly important for the application as water-retaining additives in soil. Furthermore, efficient (micro-)nutrient supply can be provided by the use of tailored hydrogels. Biodegradable polyaspartic acid (PASP) hydrogels with different available (1,6-hexamethylene diamine (HMD) and L-lysine (LYS)) and newly developed crosslinkers based on diesters of glycine (GLY) and (di-)ethylene glycol (DEG and EG, respectively) were synthesized and characterized using Fourier transform infrared (FTIR) spectroscopy and scanning electron microscopy (SEM) and regarding their swelling properties (kinetic, absorbency under load (AUL)) as well as biodegradability of PASP hydrogel. Copper (II) and zinc (II), respectively, were loaded as micronutrients in two different approaches: in situ with crosslinking and subsequent loading of prepared hydrogels. The results showed successful syntheses of di-glycine-ester-based crosslinkers. Hydrogels with good water-absorbing properties were formed. Moreover, the developed crosslinking agents in combination with the specific reaction conditions resulted in higher water absorbency with increased crosslinker content used in synthesis (10\% vs. 20\%). The prepared hydrogels are candidates for water-storing soil additives due to the biodegradability of PASP, which is shown in an exemple. The incorporation of Cu(II) and Zn(II) ions can provide these micronutrients for plant growth.}, language = {en} } @inproceedings{RuettersBragardDolls2024, author = {R{\"u}tters, Ren{\´e} and Bragard, Michael and Dolls, Sarah}, title = {The Inverted Rotary Pendulum: Facilitating Practical Teaching in Advanced Control Engineering}, series = {2024 IEEE Global Engineering Education Conference (EDUCON)}, booktitle = {2024 IEEE Global Engineering Education Conference (EDUCON)}, publisher = {IEEE}, address = {New York, NY}, issn = {2165-9559}, doi = {10.1109/EDUCON60312.2024.10578937}, pages = {5 Seiten}, year = {2024}, abstract = {This paper outlines a practical approach to teach control engineering principles, with an inverted rotary pendulum, serving as an illustrative example. It shows how the pendulum is embedded in an advanced course of control engineering. This approach is incorporated into a flipped-classroom concept, as well as classical teaching concepts, offering students practical experience in control engineering. In addition, the design of the pendulum is shown, using a Raspberry Pi as the target platform for Matlab Simulink. This pendulum can be used in the classroom to evaluate the controller design mentioned above. It is analysed if the use of the pendulum generates a deeper understanding of the learning contents.}, language = {en} } @inproceedings{BeckerBragard2024, author = {Becker, Tim and Bragard, Michael}, title = {Low-Voltage DC Training Lab for Electric Drives - Optimizing the Balancing Act Between High Student Throughput and Individual Learning Speed}, series = {2024 IEEE Global Engineering Education Conference (EDUCON)}, booktitle = {2024 IEEE Global Engineering Education Conference (EDUCON)}, publisher = {IEEE}, address = {New York, NY}, issn = {2165-9559}, doi = {10.1109/EDUCON60312.2024.10578902}, pages = {8 Seiten}, year = {2024}, abstract = {After a brief introduction of conventional laboratory structures, this work focuses on an innovative and universal approach for a setup of a training laboratory for electric machines and drive systems. The novel approach employs a central 48 V DC bus, which forms the backbone of the structure. Several sets of DC machine, asynchronous machine and synchronous machine are connected to this bus. The advantages of the novel system structure are manifold, both from a didactic and a technical point of view: Student groups can work on their own performance level in a highly parallelized and at the same time individualized way. Additional training setups (similar or different) can easily be added. Only the total power dissipation has to be provided, i.e. the DC bus balances the power flow between the student groups. Comparative results of course evaluations of several cohorts of students are shown.}, language = {en} } @article{EngelmannSimsekShalabyetal.2024, author = {Engelmann, Ulrich M. and Simsek, Beril and Shalaby, Ahmed and Krause, Hans-Joachim}, title = {Key contributors to signal generation in frequency mixing magnetic detection (FMMD): an in silico study}, series = {Sensors}, volume = {24}, journal = {Sensors}, number = {6}, publisher = {MDPI}, address = {Basel}, issn = {1424-8220}, doi = {10.3390/s24061945}, pages = {Artikel 1945}, year = {2024}, abstract = {Frequency mixing magnetic detection (FMMD) is a sensitive and selective technique to detect magnetic nanoparticles (MNPs) serving as probes for binding biological targets. Its principle relies on the nonlinear magnetic relaxation dynamics of a particle ensemble interacting with a dual frequency external magnetic field. In order to increase its sensitivity, lower its limit of detection and overall improve its applicability in biosensing, matching combinations of external field parameters and internal particle properties are being sought to advance FMMD. In this study, we systematically probe the aforementioned interaction with coupled N{\´e}el-Brownian dynamic relaxation simulations to examine how key MNP properties as well as applied field parameters affect the frequency mixing signal generation. It is found that the core size of MNPs dominates their nonlinear magnetic response, with the strongest contributions from the largest particles. The drive field amplitude dominates the shape of the field-dependent response, whereas effective anisotropy and hydrodynamic size of the particles only weakly influence the signal generation in FMMD. For tailoring the MNP properties and parameters of the setup towards optimal FMMD signal generation, our findings suggest choosing large particles of core sizes dc > 25 nm nm with narrow size distributions (σ < 0.1) to minimize the required drive field amplitude. This allows potential improvements of FMMD as a stand-alone application, as well as advances in magnetic particle imaging, hyperthermia and magnetic immunoassays.}, language = {en} } @article{OehlenschlaegerVolkmarStiefelmaieretal.2024, author = {Oehlenschl{\"a}ger, Katharina and Volkmar, Marianne and Stiefelmaier, Judith and Langsdorf, Alexander and Holtmann, Dirk and Tippk{\"o}tter, Nils and Ulber, Roland}, title = {New insights into the influence of pre-culture on robust solvent production of C. acetobutylicum}, series = {Applied Microbiology and Biotechnology}, volume = {108}, journal = {Applied Microbiology and Biotechnology}, publisher = {Springer}, address = {Berlin, Heidelberg}, issn = {1432-0614}, doi = {10.1007/s00253-023-12981-8}, pages = {10 Seiten}, year = {2024}, abstract = {Clostridia are known for their solvent production, especially the production of butanol. Concerning the projected depletion of fossil fuels, this is of great interest. The cultivation of clostridia is known to be challenging, and it is difficult to achieve reproducible results and robust processes. However, existing publications usually concentrate on the cultivation conditions of the main culture. In this paper, the influence of cryo-conservation and pre-culture on growth and solvent production in the resulting main cultivation are examined. A protocol was developed that leads to reproducible cultivations of Clostridium acetobutylicum. Detailed investigation of the cell conservation in cryo-cultures ensured reliable cell growth in the pre-culture. Moreover, a reason for the acid crash in the main culture was found, based on the cultivation conditions of the pre-culture. The critical parameter to avoid the acid crash and accomplish the shift to the solventogenesis of clostridia is the metabolic phase in which the cells of the pre-culture were at the time of inoculation of the main culture; this depends on the cultivation time of the pre-culture. Using cells from the exponential growth phase to inoculate the main culture leads to an acid crash. To achieve the solventogenic phase with butanol production, the inoculum should consist of older cells which are in the stationary growth phase. Considering these parameters, which affect the entire cultivation process, reproducible results and reliable solvent production are ensured.}, language = {en} }