@article{LambersBragard2017, author = {Lambers, Andreas and Bragard, Michael}, title = {Kinetische Skulptur - Treffen sich ein E-Techniker und ein K{\"u}nstler ...}, series = {Elektor : learn, design, share}, volume = {48}, journal = {Elektor : learn, design, share}, number = {9}, publisher = {Elektor-Verlag}, address = {Aachen}, issn = {0932-5468}, pages = {78 -- 83}, year = {2017}, abstract = {Die Verbindung der Welten dressierter Elektronen und grenzenloser Kreativit{\"a}t bietet ein großes Potential; zum Beispiel bei modernen Skulpturen, deren Form sich durch Motoren ver{\"a}ndern kann. An der FH Aachen wurde ein solches Projekt verwirklicht: Eine Matrix aus Holzkugeln kann Piktogramme anzeigen, aber auch mathematische Funktionen visualisieren. In diesem Artikel beschreiben wir die clevere Ansteuerung der Motoren.}, language = {de} } @book{NiethammerFissabre2017, author = {Niethammer, Bernhard and Fissabre, Anke}, title = {Die Steiff Spielwarenfabrik in Giengen / Brenz : Ein unbekanntes Meisterwerk der fr{\"u}hen Moderne}, publisher = {Geym{\"u}ller Verlag f{\"u}r Architektur}, address = {Aachen}, isbn = {978-3-943164-03-9}, pages = {64 S.}, year = {2017}, language = {de} } @article{HonarvarfardGamellaPoghossianetal.2017, author = {Honarvarfard, Elham and Gamella, Maria and Poghossian, Arshak and Sch{\"o}ning, Michael Josef and Katz, Evgeny}, title = {An enzyme-based reversible Controlled NOT (CNOT) logic gate operating on a semiconductor transducer}, series = {Applied Materials Today}, volume = {9}, journal = {Applied Materials Today}, publisher = {Elsevier}, address = {Amsterdam}, issn = {2352-9407}, doi = {10.1016/j.apmt.2017.08.003}, pages = {266 -- 270}, year = {2017}, abstract = {An enzyme-based biocatalytic system mimicking operation of a logically reversible Controlled NOT (CNOT) gate has been interfaced with semiconductor electronic transducers. Electrolyte-insulator-semiconductor (EIS) structures have been used to transduce chemical changes produced by the enzyme system to an electronically readable capacitive output signal using field-effect features of the EIS device. Two enzymes, urease and esterase, were immobilized on the insulating interface of EIS structure producing local pH changes performing XOR logic operation controlled by various combinations of the input signals represented by urea and ethyl butyrate. Another EIS transducer was functionalized with esterase only, thus performing Identity (ID) logic operation for the ethyl butyrate input. Both semiconductor devices assembled in parallel operated as a logically reversible CNOT gate. The present system, despite its simplicity, demonstrated for the first time logically reversible function of the enzyme system transduced electronically with the semiconductor devices. The biomolecular realization of a CNOT gate interfaced with semiconductors is promising for integration into complex biomolecular networks and future biosensor/biomedical applications.}, language = {en} } @book{Muehl2017, author = {M{\"u}hl, Thomas}, title = {Elektrische Messtechnik : Grundlagen, Messverfahren, Anwendungen}, edition = {5., {\"u}berarbeitete und erweiterte Auflage}, publisher = {Springer Vieweg}, address = {Wiesbaden}, isbn = {978-3-658-15719-7}, doi = {10.1007/978-3-658-15720-3}, pages = {XVI, 306 Seiten, Illustrationen}, year = {2017}, language = {de} } @article{Hebel2017, author = {Hebel, Christoph}, title = {Erfahrungen mit der RIN und aktuelle Weiterentwicklungen}, series = {Straßenverkehrstechnik: Organ der Forschungsgesellschaft f{\"u}r Straßen- und Verkehrswesen, der Bundesvereinigung der Straßenbau- und Verkehrsingenieure und der {\"O}sterreichischen Forschungsgesellschaft Straße und Verkehr; Zeitschrift f{\"u}r Verkehrsplanung, Verkehrsmanagement, Verkehrssicherheit, Verkehrstechnik}, volume = {61}, journal = {Straßenverkehrstechnik: Organ der Forschungsgesellschaft f{\"u}r Straßen- und Verkehrswesen, der Bundesvereinigung der Straßenbau- und Verkehrsingenieure und der {\"O}sterreichischen Forschungsgesellschaft Straße und Verkehr; Zeitschrift f{\"u}r Verkehrsplanung, Verkehrsmanagement, Verkehrssicherheit, Verkehrstechnik}, number = {7}, publisher = {Kirschbaum-Verlag}, address = {Bonn}, issn = {0039-2219}, pages = {443 -- 448}, year = {2017}, language = {de} } @article{RoehlenPilasSchoeningetal.2017, author = {R{\"o}hlen, Desiree and Pilas, Johanna and Sch{\"o}ning, Michael Josef and Selmer, Thorsten}, title = {Development of an amperometric biosensor platform for the combined determination of l-Malic, Fumaric, and l-Aspartic acid}, series = {Applied Biochemistry and Biotechnology}, volume = {183}, journal = {Applied Biochemistry and Biotechnology}, publisher = {Springer}, address = {Berlin}, issn = {1559-0291}, doi = {10.1007/s12010-017-2578-1}, pages = {566 -- 581}, year = {2017}, abstract = {Three amperometric biosensors have been developed for the detection of L-malic acid, fumaric acid, and L -aspartic acid, all based on the combination of a malate-specific dehydrogenase (MDH, EC 1.1.1.37) and diaphorase (DIA, EC 1.8.1.4). The stepwise expansion of the malate platform with the enzymes fumarate hydratase (FH, EC 4.2.1.2) and aspartate ammonia-lyase (ASPA, EC 4.3.1.1) resulted in multi-enzyme reaction cascades and, thus, augmentation of the substrate spectrum of the sensors. Electrochemical measurements were carried out in presence of the cofactor β-nicotinamide adenine dinucleotide (NAD+) and the redox mediator hexacyanoferrate (III) (HCFIII). The amperometric detection is mediated by oxidation of hexacyanoferrate (II) (HCFII) at an applied potential of + 0.3 V vs. Ag/AgCl. For each biosensor, optimum working conditions were defined by adjustment of cofactor concentrations, buffer pH, and immobilization procedure. Under these improved conditions, amperometric responses were linear up to 3.0 mM for L-malate and fumarate, respectively, with a corresponding sensitivity of 0.7 μA mM-1 (L-malate biosensor) and 0.4 μA mM-1 (fumarate biosensor). The L-aspartate detection system displayed a linear range of 1.0-10.0 mM with a sensitivity of 0.09 μA mM-1. The sensor characteristics suggest that the developed platform provides a promising method for the detection and differentiation of the three substrates.}, language = {en} } @article{PilasYaziciSelmeretal.2017, author = {Pilas, Johanna and Yazici, Yasemen and Selmer, Thorsten and Keusgen, Michael and Sch{\"o}ning, Michael Josef}, title = {Optimization of an amperometric biosensor array for simultaneous measurement of ethanol, formate, d- and l-lactate}, series = {Electrochimica Acta}, volume = {251}, journal = {Electrochimica Acta}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0013-4686}, doi = {10.1016/j.electacta.2017.07.119}, pages = {256 -- 262}, year = {2017}, abstract = {The immobilization of NAD+-dependent dehydrogenases, in combination with a diaphorase, enables the facile development of multiparametric sensing devices. In this work, an amperometric biosensor array for simultaneous determination of ethanol, formate, d- and l-lactate is presented. Enzyme immobilization on platinum thin-film electrodes was realized by chemical cross-linking with glutaraldehyde. The optimization of the sensor performance was investigated with regard to enzyme loading, glutaraldehyde concentration, pH, cofactor concentration and temperature. Under optimal working conditions (potassium phosphate buffer with pH 7.5, 2.5 mmol L-1 NAD+, 2.0 mmol L-1 ferricyanide, 25 °C and 0.4\% glutaraldehyde) the linear working range and sensitivity of the four sensor elements was improved. Simultaneous and cross-talk free measurements of four different metabolic parameters were performed successfully. The reliable analytical performance of the biosensor array was demonstrated by application in a clarified sample of inoculum sludge. Thereby, a promising approach for on-site monitoring of fermentation processes is provided.}, language = {en} } @article{AlbannaLuekeSjapicetal.2017, author = {Albanna, Walid and Lueke, Jan Niklas and Sjapic, Volha and Kotliar, Konstantin and Hescheler, J{\"u}rgen and Clusmann, Hans and Sjapic, Sergej and Alpdogan, Serdan and Schneider, Toni and Schubert, Gerrit Alexander and Neumaier, Felix}, title = {Electroretinographic Assessment of Inner Retinal Signaling in the Isolated and Superfused Murine Retina}, series = {Current Eye Research}, journal = {Current Eye Research}, number = {Article in press}, publisher = {Taylor \& Francis}, address = {London}, issn = {1460-2202}, doi = {10.1080/02713683.2017.1339807}, pages = {1 -- 9}, year = {2017}, language = {en} } @article{SeifarthGrosseGrossmannetal.2017, author = {Seifarth, Volker and Grosse, Joachim O. and Grossmann, Matthias and Janke, Heinz Peter and Arndt, Patrick and Koch, Sabine and Epple, Matthias and Artmann, Gerhard and Temiz Artmann, Ayseg{\"u}l}, title = {Mechanical induction of bi-directional orientation of primary porcine bladder smooth muscle cells in tubular fibrin-poly(vinylidene fluoride) scaffolds for ureteral and urethral repair using cyclic and focal balloon catheter stimulation}, series = {Journal of Biomaterials Applications}, volume = {32}, journal = {Journal of Biomaterials Applications}, number = {3}, publisher = {Sage}, address = {London}, issn = {1530-8022}, doi = {10.1177/0885328217723178}, pages = {321 -- 330}, year = {2017}, language = {en} } @inproceedings{BreuerGuthmannSchoeningetal.2017, author = {Breuer, Lars and Guthmann, Eric and Sch{\"o}ning, Michael Josef and Thoelen, Ronald and Wagner, Torsten}, title = {Light-Stimulated Hydrogels with Incorporated Graphene Oxide as Actuator Material for Flow Control in Microfluidic Applications}, series = {Proceedings Eurosensors 2017 Conference, Paris, France, 3-6 September 2017}, booktitle = {Proceedings Eurosensors 2017 Conference, Paris, France, 3-6 September 2017}, doi = {10.3390/proceedings1040524}, pages = {1 -- 4}, year = {2017}, language = {en} }