@incollection{FinkenbergerHerbertMalornyetal.2019, author = {Finkenberger, Isabel Maria and Herbert, Saskia and Malorny, Thomas and Koch, Christian}, title = {Perforierte Wirklichkeit und m{\"o}gliche Zuk{\"u}nfte : ein Gespr{\"a}ch}, series = {Komplement und Verst{\"a}rker : zum Verh{\"a}ltnis von Stadtplanung, k{\"u}nstlerischen Praktiken und Kulturinstitutionen}, booktitle = {Komplement und Verst{\"a}rker : zum Verh{\"a}ltnis von Stadtplanung, k{\"u}nstlerischen Praktiken und Kulturinstitutionen}, publisher = {JOVIS Verlag}, address = {Berlin}, isbn = {978-3-86859-578-9}, pages = {108 -- 129}, year = {2019}, language = {de} } @article{Finkenberger2019, author = {Finkenberger, Isabel Maria}, title = {Bodenpolitik als Instrument strategischer Transformation}, series = {UrbanLab-Magazin : Fachzeitschrift f{\"u}r Stadt- und Quartierplanung}, volume = {2019}, journal = {UrbanLab-Magazin : Fachzeitschrift f{\"u}r Stadt- und Quartierplanung}, number = {05}, pages = {18 -- 25}, year = {2019}, language = {de} } @book{OPUS4-9062, title = {Angewandte Forschung in der Wirtschaftsinformatik}, editor = {Wolf, Martin R. and Barton, Thomas and Herrmann, Frank and Meister, Vera G. and M{\"u}ller, Christian and Seel, Christian}, publisher = {Mana-Buch}, address = {Heide}, isbn = {978-3-944330-62-4}, pages = {259 Seiten}, year = {2019}, language = {de} } @inproceedings{HunsdiekChwallek2019, author = {Hunsdiek, Niklas J.A. and Chwallek, Constanze}, title = {External venturing activities and the influence of the chief technology officer}, series = {G-Forum Jahreskonferenz 2019}, booktitle = {G-Forum Jahreskonferenz 2019}, pages = {6 Seiten}, year = {2019}, language = {en} } @book{StapenhorstMeerbach2019, author = {Stapenhorst, Carolin and Meerbach, Kerstin}, title = {Studie zur forschungsbezogenen Lehre an der Fakult{\"a}t f{\"u}r Architektur der RWTH Aachen}, publisher = {RWTH Aachen}, address = {Aachen}, doi = {10.18154/rWth-2019-06163}, pages = {140 Seiten}, year = {2019}, language = {de} } @incollection{Stapenhorst2019, author = {Stapenhorst, Carolin}, title = {Heimat entwerfen?}, series = {Das Eigene und das Fremde - Heimat in Zeiten der Mobilit{\"a}t}, booktitle = {Das Eigene und das Fremde - Heimat in Zeiten der Mobilit{\"a}t}, editor = {Hasse, J{\"u}rgen}, publisher = {Karl Alber}, address = {Baden-Baden}, isbn = {978-3-495-49029-7 (print)}, doi = {10.5771/9783495817568}, pages = {215 -- 246}, year = {2019}, language = {de} } @article{EnningSchmidtWilbring2019, author = {Enning, Manfred and Schmidt, Bernd and Wilbring, Daniela}, title = {Auf dem Weg zur autonomen Anschlussbedienung}, series = {Privatbahn-Magazin}, journal = {Privatbahn-Magazin}, number = {3}, publisher = {Bahn Media}, address = {Suhlendorf}, issn = {1865-0163}, pages = {40 -- 43}, year = {2019}, language = {de} } @inproceedings{TullisCrookstonBung2019, author = {Tullis, Blake P. and Crookston, Brian M. and Bung, Daniel Bernhard}, title = {Weir head-discharge relationships: A multi-lab exercise}, series = {Proceedings of the 38th IAHR World Congress (Panama, 2019)}, booktitle = {Proceedings of the 38th IAHR World Congress (Panama, 2019)}, publisher = {IAHR}, address = {Madrid}, issn = {2521-716X (Online)}, doi = {10.3850/38WC092019-0806}, pages = {14 Seiten}, year = {2019}, abstract = {Though weir flow has been studied for centuries, there still remains some nuances of weir flow that are not well understood. Therefore, an international study was conducted in which 20 different hydraulics laboratories from around the world built and tested two linear weirs (quarter-round and half-round crested weirs) of common geometry. The only unconstrained dimension was the weir length, which could be adjusted to match the width of the test flume. Participating laboratories used the instrumentation and data collection methodologies of their choosing for head and discharge measurements. The experimental results found significant variability in the discharge coefficients as a function of dimensionless upstream head, as well as in the head-discharge relationships (as much as 50\% in some cases). Potential sources contributing to the scatter may have included head meter instrumentation, flow meter instrumentation, approach flow length (flume length upstream of weir), head measurement location, nappe behavior, laboratory measurement methods and experimental setup, and the care and skill of the investigator (human error). Analyzing the data as a function of instrumentation types, approach length, and head measurement location did not provide any insight regarding the variations. Nappe behavior (e.g., aeration), which could be influenced by laboratory-specific conditions, varied among the datasets primarily for the half-round crested weir (about 20\%).}, language = {en} } @incollection{PieronekKleefeld2019, author = {Pieronek, Lukas and Kleefeld, Andreas}, title = {The Method of Fundamental Solutions for Computing Interior Transmission Eigenvalues of Inhomogeneous Media}, series = {Integral Methods in Science and Engineering: Analytic Treatment and Numerical Approximations}, booktitle = {Integral Methods in Science and Engineering: Analytic Treatment and Numerical Approximations}, editor = {Constanda, Christian and Harris, Paul}, publisher = {Birkh{\"a}user}, address = {Cham}, isbn = {978-3-030-16077-7}, doi = {10.1007/978-3-030-16077-7_28}, pages = {353 -- 365}, year = {2019}, abstract = {The method of fundamental solutions is applied to the approximate computation of interior transmission eigenvalues for a special class of inhomogeneous media in two dimensions. We give a short approximation analysis accompanied with numerical results that clearly prove practical convenience of our alternative approach.}, language = {en} } @book{UibelPeterson2019, author = {Uibel, Thomas and Peterson, Leif Arne}, title = {Tagungsband Aachener Holzbautagung 2019}, editor = {Uibel, Thomas and Peterson, Leif Arne}, publisher = {FH Aachen}, address = {Aachen}, issn = {2197-4489}, pages = {140 Seiten ; Illustrationen, graph. Darst.}, year = {2019}, language = {de} } @misc{ReiswichBrandtCzupalla2019, author = {Reiswich, Martin and Brandt, Hannes and Czupalla, Markus}, title = {Passive thermal control by integration of phase change material into additively manufactured structures}, series = {E2. 47th Student conference}, journal = {E2. 47th Student conference}, year = {2019}, abstract = {Optical Instruments require an extremely stable thermal surrounding to prevent loss of data quality by misalignments of the instrument components resulting from material deformation due to temperature f luctuations (e.g. from solar intrusion). Phase Change Material (PCM) can be applied as a thermal damper to achieve a more uniform temperature distribution. The challenge of this method is, among others, the integration of PCM into affected areas. If correctly designed, incoming heat is latently absorbed during phase change of the PCM, i.e. the temperature of a structure remains almost constant. In a cold phase, the heat during phase change is released again latently until the PCM returns to its original state of aggregation. Thus, the structure is thermally stabilized. At FH Aachen- University of Applied Sciences research is conducted to apply PCM directly into the structures of affected components (baffles, optical benches, electronic boxes, etc.). Through the application of Additive Manufacturing, the necessary voids are directly printed into these structures and filled later with PCM. Additive Manufacturing enables complex structures that would not have been possible with conservative manufacturing methods. A corresponding Breadboard was developed and manufactured by Selective Laser Melting (SLM). The current state of research includes the handling and analysis of the Breadboard, tests and a correlation of the thermal model. The results have shown analytically and practically that it is possible to use PCM as an integral part of the structure as a thermal damper. The results serve as a basis for the further development of the technology, which should maximize performance and enable the integration of PCM into much more complex structures.}, language = {en} } @article{BaringhausGaigall2019, author = {Baringhaus, Ludwig and Gaigall, Daniel}, title = {On an asymptotic relative efficiency concept based on expected volumes of confidence regions}, series = {Statistics - A Journal of Theoretical and Applied Statistic}, volume = {53}, journal = {Statistics - A Journal of Theoretical and Applied Statistic}, number = {6}, publisher = {Taylor \& Francis}, address = {London}, issn = {1029-4910}, doi = {10.1080/02331888.2019.1683560}, pages = {1396 -- 1436}, year = {2019}, abstract = {The paper deals with an asymptotic relative efficiency concept for confidence regions of multidimensional parameters that is based on the expected volumes of the confidence regions. Under standard conditions the asymptotic relative efficiencies of confidence regions are seen to be certain powers of the ratio of the limits of the expected volumes. These limits are explicitly derived for confidence regions associated with certain plugin estimators, likelihood ratio tests and Wald tests. Under regularity conditions, the asymptotic relative efficiency of each of these procedures with respect to each one of its competitors is equal to 1. The results are applied to multivariate normal distributions and multinomial distributions in a fairly general setting.}, language = {en} } @incollection{Stapenhorst2019, author = {Stapenhorst, Carolin}, title = {Werkzeuge und ihre Wirkungsmacht}, series = {Werkbund Akademiereihe. hefte 19-20 / 2017-2018}, booktitle = {Werkbund Akademiereihe. hefte 19-20 / 2017-2018}, editor = {Deutscher Werkbund NW e.V.,}, isbn = {978-3-00-062587-9}, pages = {62 -- 74}, year = {2019}, language = {de} } @article{Gaigall2019, author = {Gaigall, Daniel}, title = {On a new approach to the multi-sample goodness-of-fit problem}, series = {Communications in Statistics - Simulation and Computation}, volume = {53}, journal = {Communications in Statistics - Simulation and Computation}, number = {10}, publisher = {Taylor \& Francis}, address = {London}, issn = {1532-4141}, doi = {10.1080/03610918.2019.1618472}, pages = {2971 -- 2989}, year = {2019}, abstract = {Suppose we have k samples X₁,₁,…,X₁,ₙ₁,…,Xₖ,₁,…,Xₖ,ₙₖ with different sample sizes ₙ₁,…,ₙₖ and unknown underlying distribution functions F₁,…,Fₖ as observations plus k families of distribution functions {G₁(⋅,ϑ);ϑ∈Θ},…,{Gₖ(⋅,ϑ);ϑ∈Θ}, each indexed by elements ϑ from the same parameter set Θ, we consider the new goodness-of-fit problem whether or not (F₁,…,Fₖ) belongs to the parametric family {(G₁(⋅,ϑ),…,Gₖ(⋅,ϑ));ϑ∈Θ}. New test statistics are presented and a parametric bootstrap procedure for the approximation of the unknown null distributions is discussed. Under regularity assumptions, it is proved that the approximation works asymptotically, and the limiting distributions of the test statistics in the null hypothesis case are determined. Simulation studies investigate the quality of the new approach for small and moderate sample sizes. Applications to real-data sets illustrate how the idea can be used for verifying model assumptions.}, language = {en} } @article{MeyerGaalenLeschingeretal.2019, author = {Meyer, Carolin and Gaalen, Kerstin van and Leschinger, Tim and Scheyerer, Max J. and Neiss, Wolfram F. and Staat, Manfred and M{\"u}ller, Lars-Peter and Wegmann, Kilian}, title = {Kyphoplasty of Osteoporotic Fractured Vertebrae: A Finite Element Analysis about Two Types of Cement}, series = {BioMed Research International}, journal = {BioMed Research International}, doi = {10.1155/2019/9232813}, pages = {Article ID 9232813}, year = {2019}, language = {en} } @article{LeschingerBirgelHackletal.2019, author = {Leschinger, Tim and Birgel, Stefan and Hackl, Michael and Staat, Manfred and M{\"u}ller, Lars-Peter and Wegmann, Kilian}, title = {A musculoskeletal shoulder simulation of moment arms and joint reaction forces after medialization of the supraspinatus footprint in rotator cuff repair}, series = {Computer Methods in Biomechanics and Biomedical Engineering}, journal = {Computer Methods in Biomechanics and Biomedical Engineering}, number = {Early view}, publisher = {Taylor \& Francis}, address = {London}, doi = {10.1080/10255842.2019.1572749}, year = {2019}, language = {en} } @article{LeschingerBeschAydinetal.2019, author = {Leschinger, Tim and Besch, Katharina and Aydin, Cansu and Staat, Manfred and Scaal, Martin and M{\"u}ller, Lars-Peter and Wegmann, Kilian}, title = {Irreparable rotator cuff tears: a biomechanical comparison of superior capsuloligamentous complex reconstruction techniques and an interposition graft technique}, series = {The Orthopaedic Journal of Sports Medicine}, volume = {7}, journal = {The Orthopaedic Journal of Sports Medicine}, number = {8}, doi = {10.1177/2325967119864590}, pages = {1 -- 5}, year = {2019}, language = {en} } @inproceedings{SchollBartellaMoluluoetal.2019, author = {Scholl, Ingrid and Bartella, Alexander K. and Moluluo, Cem and Ertural, Berat and Laing, Frederic and Suder, Sebastian}, title = {MedicVR : Acceleration and Enhancement Techniques for Direct Volume Rendering in Virtual Reality}, series = {Bildverarbeitung f{\"u}r die Medizin 2019 : Algorithmen - Systeme - Anwendungen}, booktitle = {Bildverarbeitung f{\"u}r die Medizin 2019 : Algorithmen - Systeme - Anwendungen}, publisher = {Springer Vieweg}, address = {Wiesbaden}, isbn = {978-3-658-25326-4}, doi = {10.1007/978-3-658-25326-4_32}, pages = {152 -- 157}, year = {2019}, language = {en} } @article{OrtnerHauserSchmadereretal.2019, author = {Ortner, Marion and Hauser, Christine and Schmaderer, Christoph and Muggenthaler, Claudia and Hapfelmeier, Alexander and Sorg, Christian and Diehl-Schmid, Janine and Kurz, Alexander and F{\"o}rstl, Hans and Ikenberg, Benno and Kotliar, Konstantin and Holger, Poppert and Grimmer, Timo}, title = {Decreased vascular pulsatility in Alzheimer's disease dementia measured by transcranial color-coded duplex sonography}, series = {Neuropsychiatric disease and treatment}, journal = {Neuropsychiatric disease and treatment}, number = {15}, publisher = {Dove Medical Press}, address = {Albany, Auckland}, issn = {1178-2021}, doi = {10.2147/NDT.S225754}, pages = {3487 -- 3499}, year = {2019}, abstract = {Purpose: Impaired paravascular drainage of β-Amyloid (Aβ) has been proposed as a contributing cause for sporadic Alzheimer's disease (AD), as decreased cerebral blood vessel pulsatility and subsequently reduced propulsion in this pathway could lead to the accumulation and deposition of Aβ in the brain. Therefore, we hypothesized that there is an increased impairment in pulsatility across AD spectrum. Patients and Methods: Using transcranial color-coded duplex sonography (TCCS) the resistance and pulsatility index (RI; PI) of the middle cerebral artery (MCA) in healthy controls (HC, n=14) and patients with AD dementia (ADD, n=12) were measured. In a second step, we extended the sample by adding patients with mild cognitive impairment (MCI) stratified by the presence (MCI-AD, n=8) or absence of biomarkers (MCI-nonAD, n=8) indicative for underlying AD pathology, and compared RI and PI across the groups. To control for atherosclerosis as a confounder, we measured the arteriolar-venular-ratio of retinal vessels. Results: Left and right RI (p=0.020; p=0.027) and left PI (p=0.034) differed between HC and ADD controlled for atherosclerosis with AUCs of 0.776, 0.763, and 0.718, respectively. The RI and PI of MCI-AD tended towards ADD, of MCI-nonAD towards HC, respectively. RIs and PIs were associated with disease severity (p=0.010, p=0.023). Conclusion: Our results strengthen the hypothesis that impaired pulsatility could cause impaired amyloid clearance from the brain and thereby might contribute to the development of AD. However, further studies considering other factors possibly influencing amyloid clearance as well as larger sample sizes are needed.}, language = {en} } @article{KnoedlerRuehlEmontsetal.2019, author = {Kn{\"o}dler, Matthias and R{\"u}hl, Clemens and Emonts, Jessica and Buyel, Johannes Felix}, title = {Seasonal weather changes affect the yield and quality of recombinant proteins produced in transgenic tobacco plants in a greenhouse setting}, series = {Frontiers in Plant Science}, journal = {Frontiers in Plant Science}, number = {10}, publisher = {Frontiers Media}, address = {Lausanne}, issn = {1664-462X (online-ressource)}, doi = {10.3389/fpls.2019.01245}, pages = {13 Seiten}, year = {2019}, abstract = {Transgenic plants have the potential to produce recombinant proteins on an agricultural scale, with yields of several tons per year. The cost-effectiveness of transgenic plants increases if simple cultivation facilities such as greenhouses can be used for production. In such a setting, we expressed a novel affinity ligand based on the fluorescent protein DsRed, which we used as a carrier for the linear epitope ELDKWA from the HIV-neutralizing antibody 2F5. The DsRed-2F5-epitope (DFE) fusion protein was produced in 12 consecutive batches of transgenic tobacco (Nicotiana tabacum) plants over the course of 2 years and was purified using a combination of blanching and immobilized metal-ion affinity chromatography (IMAC). The average purity after IMAC was 57 ± 26\% (n = 24) in terms of total soluble protein, but the average yield of pure DFE (12 mg kg-1) showed substantial variation (± 97 mg kg-1, n = 24) which correlated with seasonal changes. Specifically, we found that temperature peaks (>28°C) and intense illuminance (>45 klx h-1) were associated with lower DFE yields after purification, reflecting the loss of the epitope-containing C-terminus in up to 90\% of the product. Whereas the weather factors were of limited use to predict product yields of individual harvests conducted for each batch (spaced by 1 week), the average batch yields were well approximated by simple linear regression models using two independent variables for prediction (illuminance and plant age). Interestingly, accumulation levels determined by fluorescence analysis were not affected by weather conditions but positively correlated with plant age, suggesting that the product was still expressed at high levels, but the extreme conditions affected its stability, albeit still preserving the fluorophore function. The efficient production of intact recombinant proteins in plants may therefore require adequate climate control and shading in greenhouses or even cultivation in fully controlled indoor farms.}, language = {en} }