@article{EveraersKarimiVarzanehFlecketal.2020, author = {Everaers, Ralf and Karimi-Varzaneh, Hossein Ali and Fleck, Franz and Hojdis, Nils and Svaneborg, Carsten}, title = {Kremer-Grest Models for Commodity Polymer Melts: Linking Theory, Experiment, and Simulation at the Kuhn Scale}, series = {Macromolecules}, volume = {53}, journal = {Macromolecules}, number = {6}, publisher = {ACS Publications}, address = {Washington, DC}, issn = {1520-5835}, doi = {10.1021/acs.macromol.9b02428}, pages = {1901 -- 1916}, year = {2020}, abstract = {The Kremer-Grest (KG) polymer model is a standard model for studying generic polymer properties in molecular dynamics simulations. It owes its popularity to its simplicity and computational efficiency, rather than its ability to represent specific polymers species and conditions. Here we show that by tuning the chain stiffness it is possible to adapt the KG model to model melts of real polymers. In particular, we provide mapping relations from KG to SI units for a wide range of commodity polymers. The connection between the experimental and the KG melts is made at the Kuhn scale, i.e., at the crossover from the chemistry-specific small scale to the universal large scale behavior. We expect Kuhn scale-mapped KG models to faithfully represent universal properties dominated by the large scale conformational statistics and dynamics of flexible polymers. In particular, we observe very good agreement between entanglement moduli of our KG models and the experimental moduli of the target polymers.}, language = {en} } @inproceedings{LorenzAltherrPelz2020, author = {Lorenz, Imke-Sophie and Altherr, Lena and Pelz, Peter F.}, title = {Assessing and Optimizing the Resilience of Water Distribution Systems Using Graph-Theoretical Metrics}, series = {Operations Research Proceedings 2019}, booktitle = {Operations Research Proceedings 2019}, editor = {Neufeld, Janis S. and Buscher, Udo and Lasch, Rainer and M{\"o}st, Dominik and Sch{\"o}nberger, J{\"o}rn}, publisher = {Springer}, address = {Cham}, isbn = {978-3-030-48439-2}, doi = {10.1007/978-3-030-48439-2_63}, pages = {521 -- 527}, year = {2020}, abstract = {Water distribution systems are an essential supply infrastructure for cities. Given that climatic and demographic influences will pose further challenges for these infrastructures in the future, the resilience of water supply systems, i.e. their ability to withstand and recover from disruptions, has recently become a subject of research. To assess the resilience of a WDS, different graph-theoretical approaches exist. Next to general metrics characterizing the network topology, also hydraulic and technical restrictions have to be taken into account. In this work, the resilience of an exemplary water distribution network of a major German city is assessed, and a Mixed-Integer Program is presented which allows to assess the impact of capacity adaptations on its resilience.}, language = {en} } @inproceedings{LeiseSimonAltherr2020, author = {Leise, Philipp and Simon, Nicolai and Altherr, Lena}, title = {Comparison of Piecewise Linearization Techniques to Model Electric Motor Efficiency Maps: A Computational Study}, series = {Operations Research Proceedings 2019}, booktitle = {Operations Research Proceedings 2019}, publisher = {Springer}, address = {Cham}, isbn = {978-3-030-48439-2}, doi = {10.1007/978-3-030-48439-2_55}, pages = {457 -- 463}, year = {2020}, abstract = {To maximize the travel distances of battery electric vehicles such as cars or buses for a given amount of stored energy, their powertrains are optimized energetically. One key part within optimization models for electric powertrains is the efficiency map of the electric motor. The underlying function is usually highly nonlinear and nonconvex and leads to major challenges within a global optimization process. To enable faster solution times, one possibility is the usage of piecewise linearization techniques to approximate the nonlinear efficiency map with linear constraints. Therefore, we evaluate the influence of different piecewise linearization modeling techniques on the overall solution process and compare the solution time and accuracy for methods with and without explicitly used binary variables.}, language = {en} } @article{Olbertz2020, author = {Olbertz, Klaus}, title = {Jahresr{\"u}ckblick Arbeitsrecht 2019 : Gesetzes{\"a}nderungen und insbesondere im Zeichen des Befristungs- und Urlaubsrechts stehende h{\"o}chstrichterliche Rechtsprechung}, series = {NWB - Steuer- und Wirtschaftsrecht}, journal = {NWB - Steuer- und Wirtschaftsrecht}, number = {8}, publisher = {NWB-Verl.}, address = {Herne}, issn = {0028-3460}, pages = {557 -- 569}, year = {2020}, abstract = {In Fortschreibung des Jahresr{\"u}ckblicks 2018 (Olbertz, NWB 5/2019 S. 266 ) skizziert der vorliegende Beitrag die j{\"u}ngsten nennenswerten Entwicklungen im Arbeitsrecht des Jahres 2019. Im Bereich der Gesetzgebung, mit dem sich der erste Teil des Beitrags befasst, betrifft dies etwa das Fachkr{\"a}fteeinwanderungsgesetz, die angestoßenen Schutzvorschriften f{\"u}r Whistleblower oder das gesetzlich verankerte Recht auf Br{\"u}ckenteilzeit. In der arbeitsrechtlichen h{\"o}chstrichterlichen Rechtsprechung stand das Jahr 2019 insbesondere im Zeichen des Befristungs- und des Urlaubsrechts. Was hier und dar{\"u}ber hinaus wegweisend war, zeigt der zweite Teil des Beitrags.}, language = {de} } @article{Olbertz2020, author = {Olbertz, Klaus}, title = {GmbH-Gesch{\"a}ftsf{\"u}hrer: das eine Mal Arbeitnehmer, das andere Mal nicht : Arbeits- und sozialrechtliche Anwendung von Schutzvorschriften auf den Gesch{\"a}ftsf{\"u}hrer von A bis Z}, series = {NWB - Steuer- und Wirtschaftsrecht}, journal = {NWB - Steuer- und Wirtschaftsrecht}, number = {19}, publisher = {NWB-Verl.}, address = {Herne}, issn = {0028-3460}, pages = {1431 -- 1441}, year = {2020}, language = {de} } @article{Olbertz2020, author = {Olbertz, Klaus}, title = {Wenn der „leitende" Angestellte doch nur ein „normaler" Arbeitnehmer ist ... : Zur Rechtsstellung leitender Angestellter, zu Fehleinsch{\"a}tzungen des Arbeitgebers und Praxishinweisen}, series = {NWB - Steuer- und Wirtschaftsrecht}, journal = {NWB - Steuer- und Wirtschaftsrecht}, number = {32}, publisher = {NWB-Verl.}, address = {Herne}, issn = {0028-3460}, pages = {2397 -- 2406}, year = {2020}, language = {de} } @book{Timme2020, author = {Timme, Michael}, title = {WEG - Wohnungeigentumsgesetz / Hrsg. von Michael Timme . Stand 01.02.2020 ; Edition: 40}, publisher = {Beck}, address = {M{\"u}nchen}, year = {2020}, language = {de} } @book{Timme2020, author = {Timme, Michael}, title = {WEG - Wohnungeigentumsgesetz / Hrsg. von Michael Timme . Stand: 01.05.2020 ; Edition 41}, publisher = {Beck}, address = {M{\"u}nchen}, year = {2020}, language = {de} } @inproceedings{MeckMuellerAltherretal.2020, author = {Meck, Marvin M. and M{\"u}ller, Tim M. and Altherr, Lena and Pelz, Peter F.}, title = {Improving an industrial cooling system using MINLP, considering capital and operating costs}, series = {Operations Research Proceedings 2019}, booktitle = {Operations Research Proceedings 2019}, publisher = {Springer}, address = {Cham}, isbn = {978-3-030-48438-5 (Print)}, doi = {10.1007/978-3-030-48439-2_61}, pages = {505 -- 512}, year = {2020}, abstract = {The chemical industry is one of the most important industrial sectors in Germany in terms of manufacturing revenue. While thermodynamic boundary conditions often restrict the scope for reducing the energy consumption of core processes, secondary processes such as cooling offer scope for energy optimisation. In this contribution, we therefore model and optimise an existing cooling system. The technical boundary conditions of the model are provided by the operators, the German chemical company BASF SE. In order to systematically evaluate different degrees of freedom in topology and operation, we formulate and solve a Mixed-Integer Nonlinear Program (MINLP), and compare our optimisation results with the existing system.}, language = {en} } @article{MuellerLeiseLorenzetal.2020, author = {M{\"u}ller, Tim M. and Leise, Philipp and Lorenz, Imke-Sophie and Altherr, Lena and Pelz, Peter F.}, title = {Optimization and validation of pumping system design and operation for water supply in high-rise buildings}, series = {Optimization and Engineering}, volume = {2021}, journal = {Optimization and Engineering}, number = {22}, publisher = {Springer}, issn = {1573-2924}, doi = {10.1007/s11081-020-09553-4}, pages = {643 -- 686}, year = {2020}, abstract = {The application of mathematical optimization methods for water supply system design and operation provides the capacity to increase the energy efficiency and to lower the investment costs considerably. We present a system approach for the optimal design and operation of pumping systems in real-world high-rise buildings that is based on the usage of mixed-integer nonlinear and mixed-integer linear modeling approaches. In addition, we consider different booster station topologies, i.e. parallel and series-parallel central booster stations as well as decentral booster stations. To confirm the validity of the underlying optimization models with real-world system behavior, we additionally present validation results based on experiments conducted on a modularly constructed pumping test rig. Within the models we consider layout and control decisions for different load scenarios, leading to a Deterministic Equivalent of a two-stage stochastic optimization program. We use a piecewise linearization as well as a piecewise relaxation of the pumps' characteristics to derive mixed-integer linear models. Besides the solution with off-the-shelf solvers, we present a problem specific exact solving algorithm to improve the computation time. Focusing on the efficient exploration of the solution space, we divide the problem into smaller subproblems, which partly can be cut off in the solution process. Furthermore, we discuss the performance and applicability of the solution approaches for real buildings and analyze the technical aspects of the solutions from an engineer's point of view, keeping in mind the economically important trade-off between investment and operation costs.}, language = {en} } @inproceedings{MuellerAltherrLeiseetal.2020, author = {M{\"u}ller, Tim M. and Altherr, Lena and Leise, Philipp and Pelz, Peter F.}, title = {Optimization of pumping systems for buildings: Experimental validation of different degrees of model detail on a modular test rig}, series = {Operations Research Proceedings 2019}, booktitle = {Operations Research Proceedings 2019}, publisher = {Springer}, address = {Cham}, isbn = {978-3-030-48438-5}, doi = {10.1007/978-3-030-48439-2_58}, pages = {481 -- 488}, year = {2020}, abstract = {Successful optimization requires an appropriate model of the system under consideration. When selecting a suitable level of detail, one has to consider solution quality as well as the computational and implementation effort. In this paper, we present a MINLP for a pumping system for the drinking water supply of high-rise buildings. We investigate the influence of the granularity of the underlying physical models on the solution quality. Therefore, we model the system with a varying level of detail regarding the friction losses, and conduct an experimental validation of our model on a modular test rig. Furthermore, we investigate the computational effort and show that it can be reduced by the integration of domain-specific knowledge.}, language = {en} } @article{EckertAbbasiMangetal.2020, author = {Eckert, Alexander and Abbasi, Mozhdeh and Mang, Thomas and Saalw{\"a}chter, Kay and Walther, Andreas}, title = {Structure, Mechanical Properties, and Dynamics of Polyethylenoxide/Nanoclay Nacre-Mimetic Nanocomposites}, series = {Macromolecules}, volume = {53}, journal = {Macromolecules}, number = {5}, publisher = {ACS Publications}, address = {Washington, DC}, issn = {1520-5835}, doi = {10.1021/acs.macromol.9b01931}, pages = {1716 -- 1725}, year = {2020}, abstract = {Nacre-mimetic nanocomposites based on high fractions of synthetic high-aspect-ratio nanoclays in combination with polymers are continuously pushing boundaries for advanced material properties, such as high barrier against oxygen, extraordinary mechanical behavior, fire shielding, and glass-like transparency. Additionally, they provide interesting model systems to study polymers under nanoconfinement due to the well-defined layered nanocomposite arrangement. Although the general behavior in terms of forming such layered nanocomposite materials using evaporative self-assembly and controlling the nanoclay gallery spacing by the nanoclay/polymer ratio is understood, some combinations of polymer matrices and nanoclay reinforcement do not comply with the established models. Here, we demonstrate a thorough characterization and analysis of such an unusual polymer/nanoclay pair that falls outside of the general behavior. Poly(ethylene oxide) (PEO) and sodium fluorohectorite form nacre-mimetic, lamellar nanocomposites that are completely transparent and show high mechanical stiffness and high gas barrier, but there is only limited expansion of the nanoclay gallery spacing when adding increasing amounts of polymer. This behavior is maintained for molecular weights of PEO varied over four orders of magnitude and can be traced back to depletion forces. By careful investigation via X-ray diffraction and proton low-resolution solid-state NMR, we are able to quantify the amount of mobile and immobilized polymer species in between the nanoclay galleries and around proposed tactoid stacks embedded in a PEO matrix. We further elucidate the unusual confined polymer dynamics, indicating a relevant role of specific surface interactions.}, language = {en} } @incollection{EngemannDuKallweitetal.2020, author = {Engemann, Heiko and Du, Shengzhi and Kallweit, Stephan and Ning, Chuanfang and Anwar, Saqib}, title = {AutoSynPose: Automatic Generation of Synthetic Datasets for 6D Object Pose Estimation}, series = {Machine Learning and Artificial Intelligence. Proceedings of MLIS 2020}, booktitle = {Machine Learning and Artificial Intelligence. Proceedings of MLIS 2020}, publisher = {IOS Press}, address = {Amsterdam}, isbn = {978-1-64368-137-5}, doi = {10.3233/FAIA200770}, pages = {89 -- 97}, year = {2020}, abstract = {We present an automated pipeline for the generation of synthetic datasets for six-dimension (6D) object pose estimation. Therefore, a completely automated generation process based on predefined settings is developed, which enables the user to create large datasets with a minimum of interaction and which is feasible for applications with a high object variance. The pipeline is based on the Unreal 4 (UE4) game engine and provides a high variation for domain randomization, such as object appearance, ambient lighting, camera-object transformation and distractor density. In addition to the object pose and bounding box, the metadata includes all randomization parameters, which enables further studies on randomization parameter tuning. The developed workflow is adaptable to other 3D objects and UE4 environments. An exemplary dataset is provided including five objects of the Yale-CMU-Berkeley (YCB) object set. The datasets consist of 6 million subsegments using 97 rendering locations in 12 different UE4 environments. Each dataset subsegment includes one RGB image, one depth image and one class segmentation image at pixel-level.}, language = {en} } @article{EngemannDuKallweitetal.2020, author = {Engemann, Heiko and Du, Shengzhi and Kallweit, Stephan and C{\"o}nen, Patrick and Dawar, Harshal}, title = {OMNIVIL - an autonomous mobile manipulator for flexible production}, series = {Sensors}, volume = {20}, journal = {Sensors}, number = {24, art. no. 7249}, publisher = {MDPI}, address = {Basel}, isbn = {1424-8220}, doi = {10.3390/s20247249}, pages = {1 -- 30}, year = {2020}, language = {en} } @inproceedings{HoegenDonckerRuetters2020, author = {Hoegen, Anne von and Doncker, Rik W. De and R{\"u}tters, Ren{\´e}}, title = {Teaching Digital Control of Operational Amplifier Processes with a LabVIEW Interface and Embedded Hardware}, series = {2020 23rd International Conference on Electrical Machines and Systems (ICEMS)}, booktitle = {2020 23rd International Conference on Electrical Machines and Systems (ICEMS)}, publisher = {IEEE}, address = {New York, NY}, doi = {10.23919/ICEMS50442.2020.9290928}, pages = {1117 -- 1122}, year = {2020}, abstract = {Control engineering theory is hard to grasp for undergraduates during the first semesters, as it deals with the dynamical behavior of systems also in combination with control strategies on an abstract level. Therefore, operational amplifier (OpAmp) processes are reasonable and very effective systems to connect mathematical description with actual system's behavior. In this paper, we present an experiment for a laboratory session in which an embedded system, driven by a LabVIEW human machine interface (HMI) via USB, controls the analog circuits.With this setup we want to show the possibility of firstly, analyzing a first order process and secondly, designing a P-and PI-controller. Thereby, the theory of control engineering is always applied to the empirical results in order to break down the abstract level for the students.}, language = {en} } @inproceedings{UlmerBraunChengetal.2020, author = {Ulmer, Jessica and Braun, Sebastian and Cheng, Chi-Tsun and Dowey, Steve and Wollert, J{\"o}rg}, title = {Gamified Virtual Reality Training Environment for the Manufacturing Industry}, series = {Proceedings of the 2020 19th International Conference on Mechatronics - Mechatronika (ME)}, booktitle = {Proceedings of the 2020 19th International Conference on Mechatronics - Mechatronika (ME)}, publisher = {IEEE}, address = {New York, NY}, doi = {10.1109/ME49197.2020.9286661}, pages = {1 -- 6}, year = {2020}, abstract = {Industry 4.0 imposes many challenges for manufacturing companies and their employees. Innovative and effective training strategies are required to cope with fast-changing production environments and new manufacturing technologies. Virtual Reality (VR) offers new ways of on-the-job, on-demand, and off-premise training. A novel concept and evaluation system combining Gamification and VR practice for flexible assembly tasks is proposed in this paper and compared to existing works. It is based on directed acyclic graphs and a leveling system. The concept enables a learning speed which is adjustable to the users' pace and dynamics, while the evaluation system facilitates adaptive work sequences and allows employee-specific task fulfillment. The concept was implemented and analyzed in the Industry 4.0 model factory at FH Aachen for mechanical assembly jobs.}, language = {de} } @article{MoratFaudeHanssenetal.2020, author = {Morat, Mareike and Faude, Oliver and Hanssen, Henner and Ludyga, Sebastian and Zacher, Jonas and Eibl, Angi and Albracht, Kirsten and Donath, Lars}, title = {Agility Training to Integratively Promote Neuromuscular, Cognitive, Cardiovascular and Psychosocial Function in Healthy Older Adults: A Study Protocol of a One-Year Randomized-Controlled Trial}, series = {International Journal of Environmental Research and Public Health}, volume = {17}, journal = {International Journal of Environmental Research and Public Health}, number = {6}, publisher = {MDPI}, address = {Basel}, issn = {1660-4601}, doi = {10.3390/ijerph17061853}, pages = {1 -- 14}, year = {2020}, abstract = {Exercise training effectively mitigates aging-induced health and fitness impairments. Traditional training recommendations for the elderly focus separately on relevant physiological fitness domains, such as balance, flexibility, strength and endurance. Thus, a more holistic and functional training framework is needed. The proposed agility training concept integratively tackles spatial orientation, stop and go, balance and strength. The presented protocol aims at introducing a two-armed, one-year randomized controlled trial, evaluating the effects of this concept on neuromuscular, cardiovascular, cognitive and psychosocial health outcomes in healthy older adults. Eighty-five participants were enrolled in this ongoing trial. Seventy-nine participants completed baseline testing and were block-randomized to the agility training group or the inactive control group. All participants undergo pre- and post-testing with interim assessment after six months. The intervention group currently receives supervised, group-based agility training twice a week over one year, with progressively demanding perceptual, cognitive and physical exercises. Knee extension strength, reactive balance, dual task gait speed and the Agility Challenge for the Elderly (ACE) serve as primary endpoints and neuromuscular, cognitive, cardiovascular, and psychosocial meassures serve as surrogate secondary outcomes. Our protocol promotes a comprehensive exercise training concept for older adults, that might facilitate stakeholders in health and exercise to stimulate relevant health outcomes without relying on excessively time-consuming physical activity recommendations.}, language = {en} } @article{KetelhutBrueggeGoelletal.2020, author = {Ketelhut, Maike and Br{\"u}gge, G. M. and G{\"o}ll, Fabian and Braunstein, Bjoern and Albracht, Kirsten and Abel, Dirk}, title = {Adaptive iterative learning control of an industrial robot during neuromuscular training}, series = {IFAC PapersOnLine}, volume = {53}, journal = {IFAC PapersOnLine}, number = {2}, publisher = {Elsevier}, address = {Amsterdam}, issn = {2405-8963}, doi = {10.1016/j.ifacol.2020.12.741}, pages = {16468 -- 16475}, year = {2020}, abstract = {To prevent the reduction of muscle mass and loss of strength coming along with the human aging process, regular training with e.g. a leg press is suitable. However, the risk of training-induced injuries requires the continuous monitoring and controlling of the forces applied to the musculoskeletal system as well as the velocity along the motion trajectory and the range of motion. In this paper, an adaptive norm-optimal iterative learning control algorithm to minimize the knee joint loadings during the leg extension training with an industrial robot is proposed. The response of the algorithm is tested in simulation for patients with varus, normal and valgus alignment of the knee and compared to the results of a higher-order iterative learning control algorithm, a robust iterative learning control and a recently proposed conventional norm-optimal iterative learning control algorithm. Although significant improvements in performance are made compared to the conventional norm-optimal iterative learning control algorithm with a small learning factor, for the developed approach as well as the robust iterative learning control algorithm small steady state errors occur.}, language = {en} } @misc{OPUS4-10964, title = {Ordnung zur Aufhebung der Pr{\"u}fungsordnung f{\"u}r die Masterstudieng{\"a}nge „Energiewirtschaft \& Informatik" (3 Semester) und „Energiewirtschaft \& Informatik" (4 Semester) vom 4. Mai 2016 (FH-Mitteilung Nr. 59/2016) Fachbereich Energietechnik Fachbereich Medizintechnik und Technomathematik an der Fachhochschule Aachen : vom 16. Januar 2020}, organization = {FH Aachen}, pages = {3 Seiten}, year = {2020}, language = {de} } @misc{OPUS4-10965, title = {Verwaltungs- und Benutzungsordnung des Solar-Instituts J{\"u}lich (SIJ) : vom 27. Januar 2020}, organization = {FH Aachen}, pages = {5 Seiten}, year = {2020}, language = {de} } @misc{OPUS4-10966, title = {Verwaltungs- und Benutzungsordnung des Solar-Instituts J{\"u}lich (SIJ) vom 27. Januar 2020 : berichtigt durch Bekanntmachung vom 18. M{\"a}rz 2020 (FH-Mitteilung Nr. 27/2020)}, organization = {FH Aachen}, pages = {5 Seiten}, year = {2020}, language = {de} } @misc{SchulzeBuxlohGrossCheng2020, author = {Schulze-Buxloh, Lina and Groß, Rolf Fritz and Cheng, Kevin Toni}, title = {Development and manufacturing of an interactive three-dimensional phase diagram of carbon dioxide for teaching sessions in thermodynamics}, series = {Proceedings of the International Conference The Future of Education 2020}, journal = {Proceedings of the International Conference The Future of Education 2020}, year = {2020}, language = {en} } @inproceedings{BedburMoorkampPetersonetal.2020, author = {Bedbur, Christian and Moorkamp, Wilfried and Peterson, Leif Arne and Uibel, Thomas}, title = {Holzbr{\"u}cken mit Natursteinbel{\"a}gen - Untersuchungen zur Aktivierung der Verbundwirkung}, series = {Doktorandenkolloquium Holzbau Forschung + Praxis 2020}, booktitle = {Doktorandenkolloquium Holzbau Forschung + Praxis 2020}, editor = {Kuhlmann, Ulrike}, publisher = {Universit{\"a}t Stuttgart, Institut f{\"u}r Konstruktion und Entwurf}, address = {Stuttgart}, pages = {53 -- 60}, year = {2020}, language = {de} } @inproceedings{IomdinaKiselevaKotliaretal.2020, author = {Iomdina, Elena N. and Kiseleva, Anna A. and Kotliar, Konstantin and Luzhnov, Petr V.}, title = {Quantification of Choroidal Blood Flow Using the OCT-A System Based on Voxel Scan Processing}, series = {Proceedings of the International Conference on Biomedical Innovations and Applications- BIA 2020}, booktitle = {Proceedings of the International Conference on Biomedical Innovations and Applications- BIA 2020}, publisher = {IEEE}, address = {New York, NY}, isbn = {978-1-7281-7073-2}, doi = {10.1109/BIA50171.2020.9244511}, pages = {41 -- 44}, year = {2020}, abstract = {The paper presents a method for the quantitative assessment of choroidal blood flow using an OCT-A system. The developed technique for processing of OCT-A scans is divided into two stages. At the first stage, the identification of the boundaries in the selected portion was performed. At the second stage, each pixel mark on the selected layer was represented as a volume unit, a voxel, which characterizes the region of moving blood. Three geometric shapes were considered to represent the voxel. On the example of one OCT-A scan, this work presents a quantitative assessment of the blood flow index. A possible modification of two-stage algorithm based on voxel scan processing is presented.}, language = {en} } @article{MalanHamerKaeneletal.2020, author = {Malan, Leone and Hamer, Mark and K{\"a}nel, Roland von and Kotliar, Konstantin and Wyk, Roelof D. van and Lambert, Gavin W. and Vilser, Walthard and Ziemssen, Tjalf and Schlaich, Markus P. and Smith, Wayne and Magnusson, Martin and Wentzel, Annemarie and Myburgh, Carlien E. and Steyn, Hendrik S. and Malan, Nico T.}, title = {Delayed retinal vein recovery responses indicate both non-adaptation to stress as well as increased risk for stroke: the SABPA study}, series = {Cardiovascular Journal of Africa}, volume = {26}, journal = {Cardiovascular Journal of Africa}, number = {31}, publisher = {Clinics Cardive Publishing}, address = {Durbanville}, issn = {1680-0745}, doi = {10.5830/CVJA-2020-031}, pages = {1 -- 12}, year = {2020}, language = {en} } @article{StreeseKotliarDeiserothetal.2020, author = {Streese, Lukas and Kotliar, Konstantin and Deiseroth, Arne and Infanger, Denis and Gugleta, Konstantin and Schmaderer, Christoph and Hanssen, Henner}, title = {Retinal endothelial function in cardiovascular risk patients: A randomized controlled exercise trial}, series = {Scandinavian Journal of Medicine and Science in Sports}, volume = {30}, journal = {Scandinavian Journal of Medicine and Science in Sports}, number = {2}, publisher = {Wiley}, address = {Oxford}, issn = {1600-0838}, doi = {10.1111/sms.13560}, pages = {272 -- 280}, year = {2020}, abstract = {The aim of this study was to investigate, for the first time, the effects of high-intensity interval training (HIIT) on retinal microvascular endothelial function in cardiovascular (CV) risk patients. In the randomized controlled trial, middle-aged and previously sedentary patients with increased CV risk (aged 58 ± 6 years) with ≥ two CV risk factors were randomized into a 12-week HIIT (n = 33) or control group (CG, n = 36) with standard physical activity recommendations. A blinded examiner measured retinal endothelial function by flicker light-induced maximal arteriolar (ADmax) and venular (VDmax) dilatation as well as the area under the arteriolar (AFarea) and venular (VFarea) flicker curve using a retinal vessel analyzer. Standardized assessments of CV risk factors, cardiorespiratory fitness, and retinal endothelial function were performed before and after HIIT. HIIT reduced body mass index, fat mass, and low-density lipoprotein and increased muscle mass and peak oxygen uptake (VO2peak). Both ADmax (pre: 2.7 ± 2.1\%, post: 3.0 ± 2.2\%, P = .018) and AFarea (pre: 32.6 ± 28.4\%*s, post: 37.7 ± 30.6\%*s, P = .016) increased after HIIT compared with CG (ADmax, pre: 3.2 ± 1.8\%, post: 2.9 ± 1.8\%, P = .254; AFarea, pre: 41.6 ± 28.5\%*s, post: 37.8 ± 27.0\%*s, P = .186). Venular function remained unchanged after HIIT. There was a significant association between ∆-change VO2peak and ∆-changes ADmax and AFarea (P = .026, R² = 0.073; P = .019, R² = 0.081, respectively). 12-weeks of HIIT improved retinal endothelial function in middle-aged patients with increased CV risk independent of the reduction in classical CV risk factors. Exercise has the potential to reverse or at least postpone progression of small vessel disease in older adults with increased CV risk under standard medication. Dynamic retinal vessel analysis seems to be a sensitive tool to detect treatment effects of exercise interventions on retinal microvascular endothelial function in middle-aged individuals with increased CV risk.}, language = {en} } @article{HamouKotliarTanetal.2020, author = {Hamou, Hussam Aldin and Kotliar, Konstantin and Tan, Sonny Kian and Weiß, Christel and Blume, Christian and Clusmann, Hans and Schubert, Gerrit Alexander and Albanna, Walid}, title = {Surgical nuances and placement of subgaleal drains for supratentorial procedures—a prospective analysis of efficacy and outcome in 150 craniotomies}, series = {Acta Neurochirurgica}, volume = {2020}, journal = {Acta Neurochirurgica}, number = {162}, publisher = {Springer Nature}, address = {Cham}, issn = {0942-0940}, doi = {10.1007/s00701-019-04196-6}, pages = {729 -- 736}, year = {2020}, abstract = {Background For supratentorial craniotomy, surgical access, and closure technique, including placement of subgaleal drains, may vary considerably. The influence of surgical nuances on postoperative complications such as cerebrospinal fluid leakage or impaired wound healing overall remains largely unclear. With this study, we are reporting our experiences and the impact of our clinical routines on outcome in a prospectively collected data set. Method We prospectively observed 150 consecutive patients undergoing supratentorial craniotomy and recorded technical variables (type/length of incision, size of craniotomy, technique of dural and skin closure, type of dressing, and placement of subgaleal drains). Outcome variables (subgaleal hematoma/CSF collection, periorbital edema, impairment of wound healing, infection, and need for operative revision) were recorded at time of discharge and at late follow-up. Results Early subgaleal fluid collection was observed in 36.7\% (2.8\% at the late follow-up), and impaired wound healing was recorded in 3.3\% of all cases, with an overall need for operative revision of 6.7\%. Neither usage of dural sealants, lack of watertight dural closure, and presence of subgaleal drains, nor type of skin closure or dressing influenced outcome. Curved incisions, larger craniotomy, and tumor size, however, were associated with an increase in early CSF or hematoma collection (p < 0.0001, p = 0.001, p < 0.01 resp.), and larger craniotomy size was associated with longer persistence of subgaleal fluid collections (p < 0.05). Conclusions Based on our setting, individual surgical nuances such as the type of dural closure and the use of subgaleal drains resulted in a comparable complication rate and outcome. Subgaleal fluid collections were frequently observed after supratentorial procedures, irrespective of the closing technique employed, and resolve spontaneously in the majority of cases without significant sequelae. Our results are limited due to the observational nature in our single-center study and need to be validated by supportive prospective randomized design.}, language = {en} } @article{RamoshabaHuismanLammertynetal.2020, author = {Ramoshaba, Nthai E. and Huisman, Hugo W. and Lammertyn, Leandi and Kotliar, Konstantin and Schutte, Aletta E. and Smith, Wayne}, title = {Retinal microvasculature and masked hypertension in young adults: the African-PREDICT study}, series = {Hypertension Research}, journal = {Hypertension Research}, number = {43}, publisher = {Springer Nature}, address = {Osaka}, issn = {1348-4214}, doi = {10.1038/s41440-020-0487-0}, pages = {1231 -- 1238}, year = {2020}, abstract = {Masked hypertension is known to induce microvascular complications. However, it is unclear whether early microvascular changes are already occurring in young, otherwise healthy adults. We therefore investigated whether retinal microvascular calibers and acute responses to a flicker stimulus are related to masked hypertension. We used the baseline data of 889 participants aged 20-30 years who were taking part in the African Prospective study on the Early Detection and Identification of Cardiovascular Disease and Hypertension. Clinic and 24-h ambulatory blood pressure were measured. The central retinal artery equivalent (CRAE) and central retinal vein equivalent were calculated from fundus images, and retinal vessel dilation was determined in response to flicker light-induced provocation. A smaller CRAE was observed in those with masked hypertension vs. those with normotension (157.1 vs. 161.2 measuring units, P < 0.001). In forward multivariable-adjusted regression analysis, only CRAE was negatively related to masked hypertension [adjusted R² = 0.267, β = -0.097 (95\% CI = -0.165; -0.029), P = 0.005], but other retinal microvascular parameters were not associated with masked hypertension. In multivariable logistic regression analyses, masked hypertension [OR = 2.333, (95\% CI = 1.316; 4.241), P = 0.004] was associated with a narrower CRAE. In young healthy adults, masked hypertension was associated with retinal arteriolar narrowing, thereby reflecting early microvascular alterations known to predict cardiovascular outcomes in later life.}, language = {en} } @article{SmithKotliarLammertynetal.2020, author = {Smith, Wayne and Kotliar, Konstantin and Lammertyn, Leandi and Ramoshaba, Nthai E. and Vilser, Walthard and Huisman, Hugo W. and Schutte, Aletta E.}, title = {Retinal vessel caliber and caliber responses in true normotensive black and white adults: The African-PREDICT study}, series = {Microvascular Research}, volume = {128}, journal = {Microvascular Research}, number = {Article 103937}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0026-2862}, doi = {10.1016/j.mvr.2019.103937}, year = {2020}, abstract = {Purpose Globally, a detrimental shift in cardiovascular disease risk factors and a higher mortality level are reported in some black populations. The retinal microvasculature provides early insight into the pathogenesis of systemic vascular diseases, but it is unclear whether retinal vessel calibers and acute retinal vessel functional responses differ between young healthy black and white adults. Methods We included 112 black and 143 white healthy normotensive adults (20-30 years). Retinal vessel calibers (central retinal artery and vein equivalent (CRAE and CRVE)) were calculated from retinal images and vessel caliber responses to flicker light induced provocation (FLIP) were determined. Additionally, ambulatory blood pressure (BP), anthropometry and blood samples were collected. Results The groups displayed similar 24 h BP profiles and anthropometry (all p > .24). Black participants demonstrated a smaller CRAE (158 ± 11 vs. 164 ± 11 MU, p < .001) compared to the white group, whereas CRVE was similar (p = .57). In response to FLIP, artery maximal dilation was greater in the black vs. white group (5.6 ± 2.1 vs. 3.3 ± 1.8\%; p < .001). Conclusions Already at a young age, healthy black adults showed narrower retinal arteries relative to the white population. Follow-up studies are underway to show if this will be related to increased risk for hypertension development. The reason for the larger vessel dilation responses to FLIP in the black population is unclear and warrants further investigation.}, language = {en} } @inproceedings{HauggKreyerKemperetal.2020, author = {Haugg, Albert Thomas and Kreyer, J{\"o}rg and Kemper, Hans and Hatesuer, Katerina and Esch, Thomas}, title = {Heat exchanger for ORC. adaptability and optimisation potentials}, series = {IIR International Rankine 2020 Conference}, booktitle = {IIR International Rankine 2020 Conference}, doi = {10.18462/iir.rankine.2020.1224}, pages = {10 Seiten}, year = {2020}, abstract = {The recovery of waste heat requires heat exchangers to extract it from a liquid or gaseous medium into another working medium, a refrigerant. In Organic Rankine Cycles (ORC) on Combustion Engines there are two major heat sources, the exhaust gas and the water/glycol fluid from the engine's cooling circuit. A heat exchanger design must be adapted to the different requirements and conditions resulting from the heat sources, fluids, system configurations, geometric restrictions, and etcetera. The Stacked Shell Cooler (SSC) is a new and very specific design of a plate heat exchanger, created by AKG, which allows with a maximum degree of freedom the optimization of heat exchange rate and the reduction of the related pressure drop. This optimization in heat exchanger design for ORC systems is even more important, because it reduces the energy consumption of the system and therefore maximizes the increase in overall efficiency of the engine.}, language = {en} } @incollection{AtmaneHirechKassmietal.2020, author = {Atmane, Ilias and Hirech, Kamal and Kassmi, K. and Mahdi, Zahra and Alexopoulos, Spiros and Schwarzer, Klemens and Chayeb, H. and Bachiri, N.}, title = {Design and realization of a pilot solar desalination plant in Douar El Hamri in the province of Berkane (Morocco)}, series = {Sustainable entrepreneurship, renewable energy-based projects, and digitalization}, booktitle = {Sustainable entrepreneurship, renewable energy-based projects, and digitalization}, editor = {Omrane, Amina and Kassmi, Khalil and Akram, Muhammad Wasim and Khanna, Ashish and Mostafiz, Imtiaz}, publisher = {CRC Press}, address = {Boca Raton, Fa.}, isbn = {9781000292541 (E-Book)}, pages = {18 Seiten}, year = {2020}, abstract = {Producing fresh water from saline water has become one of the most difficult challenges to overcome especially with the high demand and shortage of fresh water. In this context, as part of a collaboration with Germany, the authors propose a design and implementation of a pilot multi-stage solar desalination system (MSD), remotely controlled, at Douar Al Hamri in the rural town of Boughriba in the province of Berkane, Morocco. More specifically, they present their contribution on the remote control and supervision system, which makes the functioning of the MSD system reliable and guarantees the production of drinking water for the population of Douar. The results obtained show that the electronic cards and computer communication software implemented allow the acquisition of all electrical (currents, voltages, powers, yields), thermal (temperatures of each stage), and meteorological (irradiance and ambient temperature), remote control and maintenance (switching on, off, data transfer). By comparing with the literature carried out in the field of solar energy, the authors conclude that the MSD and electronic desalination systems realized during this work represent a contribution in terms of the reliability and durability of providing drinking water in rural and urban areas.}, language = {en} } @article{GoettenHavermannBraunetal.2020, author = {G{\"o}tten, Falk and Havermann, Marc and Braun, Carsten and Marino, Matthew and Bil, Cees}, title = {Improved Form Factor for Drag Estimation of Fuselages with Various Cross Sections}, series = {Journal of Aircraft}, journal = {Journal of Aircraft}, publisher = {AIAA}, address = {Reston, Va.}, issn = {1533-3868}, doi = {10.2514/1.C036032}, pages = {1 -- 13}, year = {2020}, abstract = {The paper presents an aerodynamic investigation of 70 different streamlined bodies with fineness ratios ranging from 2 to 10. The bodies are chosen to idealize both unmanned and small manned aircraft fuselages and feature cross-sectional shapes that vary from circular to quadratic. The study focuses on friction and pressure drag in dependency of the individual body's fineness ratio and cross section. The drag forces are normalized with the respective body's wetted area to comply with an empirical drag estimation procedure. Although the friction drag coefficient then stays rather constant for all bodies, their pressure drag coefficients decrease with an increase in fineness ratio. Referring the pressure drag coefficient to the bodies' cross-sectional areas shows a distinct pressure drag minimum at a fineness ratio of about three. The pressure drag of bodies with a quadratic cross section is generally higher than for bodies of revolution. The results are used to derive an improved form factor that can be employed in a classic empirical drag estimation method. The improved formulation takes both the fineness ratio and cross-sectional shape into account. It shows superior accuracy in estimating streamlined body drag when compared with experimental data and other form factor formulations of the literature.}, language = {en} } @article{RegerKuhnhenneEbbertetal.2020, author = {Reger, Vitali and Kuhnhenne, Markus and Ebbert, Thiemo and Hachul, Helmut and Blanke, Tobias and D{\"o}ring, Bernd}, title = {Nutzung erneuerbarer Energien durch thermische Aktivierung von Komponenten aus Stahl}, series = {Stahlbau}, volume = {2020}, journal = {Stahlbau}, number = {Volume 89, Issue 6512-519}, publisher = {Ernst \& Sohn}, address = {Berlin}, issn = {1437-1049}, doi = {10.1002/stab.202000031}, pages = {512 -- 519}, year = {2020}, abstract = {Die Versorgung von Neubauten soll m{\"o}glichst weitgehend unabh{\"a}ngig von fossilen Energietr{\"a}gern erfolgen. Erneuerbare Energien spielen daf{\"u}r eine gewichtige Rolle. Eine gute M{\"o}glichkeit, erneuerbare Energien ohne viel zus{\"a}tzlichen Aufwand nutzbar zu machen, ist, bereits vorhandenen Komponenten im Geb{\"a}ude zus{\"a}tzliche Funktionen zu geben. Hier kann bspw. die Fassade oder das Dach solarthermisch aktiviert oder durch Fotovoltaikmodule erg{\"a}nzt werden. Auch Tiefgr{\"u}ndungen k{\"o}nnen neben der statischen Funktion noch eine geothermische Funktion zur Aufnahme oder Abgabe von W{\"a}rme erhalten. Neben der Erzeugung bietet sich auch f{\"u}r die Verteilung der W{\"a}rme oder K{\"a}lte im Geb{\"a}ude die Integration in Bauteile an. Hier kann bspw. der Boden durch eine Fußbodenheizung oder die Decke durch Deckenstrahlplatten aktiviert werden. Im Rahmen der Ver{\"o}ffentlichung wird auf die thermische Aktivierung von Stahlkomponenten eingegangen. Es wird eine L{\"o}sung vorgestellt, die vorgeh{\"a}ngte hinterl{\"u}ftete Stahlfassade (VHF) solarthermisch zu aktivieren. Außerdem werden zwei M{\"o}glichkeiten zur geothermischen Aktivierung von Tiefgr{\"u}ndungen mittels Stahlpf{\"a}hlen gezeigt. Zuletzt wird ein System zur thermischen Aktivierung von Stahltrapezprofilen an der Decke erl{\"a}utert, welches W{\"a}rme zuf{\"u}hren oder bei Bedarf abf{\"u}hren kann.}, language = {de} } @article{WildSchrezenmeierCzupallaetal.2020, author = {Wild, Dominik and Schrezenmeier, Johannes and Czupalla, Markus and F{\"o}rstner, Roger}, title = {Thermal Characterization of additive manufactured Integral Structures for Phase Change Applications}, series = {2020 International Conference on Environmental Systems}, journal = {2020 International Conference on Environmental Systems}, publisher = {Texas Tech University}, year = {2020}, abstract = {"Infused Thermal Solutions" (ITS) introduces a method for passive thermal control to stabilize structural components thermally without active heating and cooling systems, by using phase change material (PCM) in combination with lattice - both embedded into an additive manufactured integral structure. The technology is currently under development. This paper presents the results of the thermal property measurements performed on additive manufactured ITS breadboards. Within the breadboard campaigns key characteristics of the additive manufactured specimens were derived: Mechanical parameters: specimen impermeability, minimum wall thickness, lattice structure, subsequent heat treatment. Thermal properties: thermo-optical surface properties of the additive manufactured raw material, thermal conductivity and specific heat capacity measurements. As a conclusion the paper introduces an overview of potential ITS hardware applications, expected to increase the thermal performance.}, language = {en} } @article{RaffeisAdjeiKyeremehVroomenetal.2020, author = {Raffeis, Iris and Adjei-Kyeremeh, Frank and Vroomen, Uwe and Westhoff, Elmar and Bremen, Sebastian and Hohoi, Alexandru and B{\"u}hrig-Polaczek, Andreas}, title = {Qualification of a Ni-Cu alloy for the laser powder bed fusion process (LPBF): Its microstructure and mechanical properties}, series = {Applied Sciences}, volume = {10}, journal = {Applied Sciences}, number = {Art. 3401}, publisher = {MDPI}, address = {Basel}, issn = {2076-3417}, doi = {10.3390/app10103401}, pages = {1 -- 15}, year = {2020}, abstract = {As researchers continue to seek the expansion of the material base for additive manufacturing, there is a need to focus attention on the Ni-Cu group of alloys which conventionally has wide industrial applications. In this work, the G-NiCu30Nb casting alloy, a variant of the Monel family of alloys with Nb and high Si content is, for the first time, processed via the laser powder bed fusion process (LPBF). Being novel to the LPBF processes, optimum LPBF parameters were determined, and hardness and tensile tests were performed in as-built conditions and after heat treatment at 1000 °C. Microstructures of the as-cast and the as-built condition were compared. Highly dense samples (99.8\% density) were achieved after varying hatch distance (80 µm and 140 µm) with scanning speed (550 mm/s-1500 mm/s). There was no significant difference in microhardness between varied hatch distance print sets. Microhardness of the as-built condition (247 HV0.2) exceeded the as-cast microhardness (179 HV0.2.). Tensile specimens built in vertical (V) and horizontal (H) orientations revealed degrees of anisotropy and were superior to conventionally reported figures. Post heat treatment increased ductility from 20\% to 31\% (V), as well as from 16\% to 25\% (H), while ultimate tensile strength (UTS) and yield strength (YS) were considerably reduced.}, language = {en} } @article{BayerTemizArtmannDigeletal.2020, author = {Bayer, Robin and Temiz Artmann, Ayseg{\"u}l and Digel, Ilya and Falkenstein, Julia and Artmann, Gerhard and Creutz, Till and Hescheler, J{\"u}rgen}, title = {Mechano-pharmacological testing of L-Type Ca²⁺ channel modulators via human vascular celldrum model}, series = {Cellular Physiology and Biochemistry}, volume = {54}, journal = {Cellular Physiology and Biochemistry}, publisher = {Cell Physiol Biochem Press}, address = {D{\"u}sseldorf}, issn = {1421-9778}, doi = {10.33594/000000225}, pages = {371 -- 383}, year = {2020}, abstract = {Background/Aims: This study aimed to establish a precise and well-defined working model, assessing pharmaceutical effects on vascular smooth muscle cell monolayer in-vitro. It describes various analysis techniques to determine the most suitable to measure the biomechanical impact of vasoactive agents by using CellDrum technology. Methods: The so-called CellDrum technology was applied to analyse the biomechanical properties of confluent human aorta muscle cells (haSMC) in monolayer. The cell generated tensions deviations in the range of a few N/m² are evaluated by the CellDrum technology. This study focuses on the dilative and contractive effects of L-type Ca²⁺ channel agonists and antagonists, respectively. We analyzed the effects of Bay K8644, nifedipine and verapamil. Three different measurement modes were developed and applied to determine the most appropriate analysis technique for the study purpose. These three operation modes are called, particular time mode" (PTM), "long term mode" (LTM) and "real-time mode" (RTM). Results: It was possible to quantify the biomechanical response of haSMCs to the addition of vasoactive agents using CellDrum technology. Due to the supplementation of 100nM Bay K8644, the tension increased approximately 10.6\% from initial tension maximum, whereas, the treatment with nifedipine and verapamil caused a significant decrease in cellular tension: 10nM nifedipine decreased the biomechanical stress around 6,5\% and 50nM verapamil by 2,8\%, compared to the initial tension maximum. Additionally, all tested measurement modes provide similar results while focusing on different analysis parameters. Conclusion: The CellDrum technology allows highly sensitive biomechanical stress measurements of cultured haSMC monolayers. The mechanical stress responses evoked by the application of vasoactive calcium channel modulators were quantified functionally (N/m²). All tested operation modes resulted in equal findings, whereas each mode features operation-related data analysis.}, language = {en} } @article{DigelKernGeenenetal.2020, author = {Digel, Ilya and Kern, Inna and Geenen, Eva-Maria and Akimbekov, Nuraly S.}, title = {Dental plaque removal by ultrasonic toothbrushes}, series = {dentistry journal}, volume = {8}, journal = {dentistry journal}, number = {28}, publisher = {MDPI}, address = {Basel}, issn = {2304-6767}, doi = {10.3390/dj8010028}, pages = {1 -- 13}, year = {2020}, abstract = {With the variety of toothbrushes on the market, the question arises, which toothbrush is best suited to maintain oral health? This thematic review focuses first on plaque formation mechanisms and then on the plaque removal effectiveness of ultrasonic toothbrushes and their potential in preventing oral diseases like periodontitis, gingivitis, and caries. We overviewed the physical effects that occurred during brushing and tried to address the question of whether ultrasonic toothbrushes effectively reduced the microbial burden by increasing the hydrodynamic forces. The results of published studies show that electric toothbrushes, which combine ultrasonic and sonic (or acoustic and mechanic) actions, may have the most promising effect on good oral health. Existing ultrasonic/sonic toothbrush models do not significantly differ regarding the removal of dental biofilm and the reduction of gingival inflammation compared with other electrically powered toothbrushes, whereas the manual toothbrushes show a lower effectiveness.}, language = {en} } @incollection{AkimbekovZhanadilovnaUalievaetal.2020, author = {Akimbekov, Nuraly S. and Zhanadilovna, Abdieva G. and Ualieva, Perizat S. and Abaihanovna, Zhusipova D. and Digel, Ilya and Savitskaya, Irina S. and Zhubanova, Azhar Achmet}, title = {Functionalization of Carbon Based Wound Dressings with Antimicrobial Phytoextracts for Bioactive Treatment of Septic Wounds}, series = {Carbon Nanomaterials in Biomedicine and the Environment}, booktitle = {Carbon Nanomaterials in Biomedicine and the Environment}, publisher = {Jenny Stanford Publishing}, address = {Singapore}, isbn = {978-981-4800-27-3}, doi = {10.1201/9780429428647-11}, pages = {211 -- 228}, year = {2020}, abstract = {The treatment of septic wounds with curative dressings based on biocomposites containing sage and marigold phytoextracts was effective in in vitro and in vivo experiments. These dressings caused the purification of the wound surface from purulent-necrotic masses three days earlier than in the other experimental groups. The consequence of an increase in incidents of severe course of the wound and the observed tendency to increase the number of adverse effects is the development of long-term recurrent wound processes. To treat purulent wounds, the following tactics were used: The purulent wounds of animals were covered with the examined wound dressing, and then the next day samples were taken, the procedure was performed once in 2 days. To obtain the active nanostructured sorbents such as carbonized rice husks, they are functionalized with biologically active components possessing antimicrobial, anti-inflammatory, antitoxic, immunomodulating, antiallergic and other types of properties.}, language = {en} } @incollection{SavitskayaKistaubayevaAkimbekovetal.2020, author = {Savitskaya, Irina S. and Kistaubayeva, Aida S. and Akimbekov, Nuraly S. and Digel, Ilya and Shokatayeva, Dina and Zhubanova, Azhar Achmet}, title = {Prospective Use of Probiotics Immobilized on Sorbents with Nanostructured Surfaces}, series = {Carbon Nanomaterials in Biomedicine and the Environment}, booktitle = {Carbon Nanomaterials in Biomedicine and the Environment}, publisher = {Jenny Stanford Publishing}, address = {Singapore}, isbn = {978-981-4800-27-3}, doi = {10.1201/9780429428647-12}, pages = {229 -- 267}, year = {2020}, abstract = {Activated carbons are known as excellent adsorbents. Their applications include the adsorptive removal of color, odor, taste, undesirable organic and inorganic pollutants from drinking and waste water; air purification in inhabited spaces; purification of many chemicals, pharmaceutical products and many others. This chapter elucidates the role of normal microflora in the maintenance of human health and presents materials on possible clinical displays of microecological infringements and ways of their correction. It presents new developments concerning new probiotics with immobilized Lactobacillus and Bacillus. The chapter considers the mechanisms of the intestine disbacteriosis correction by sorbed probiotics. It demonstrates the advantages and creation prospects of immobilized probiotics developed on the basis of carbonized rice husk. There are great prospects for the development of medical biotechnology due to use of carbon sorbents with a nanostructured surface. Microbial communities form a biocenosis of the biotope and together with the host organism create permanent or temporary ecosystems.}, language = {en} } @incollection{ZhubanovaMansurovDigel2020, author = {Zhubanova, Azhar A. and Mansurov, Zulkhair A. and Digel, Ilya}, title = {Use of Advanced Nanomaterials for Bioremediation of Contaminated Ecosystems}, series = {Carbon Nanomaterials in Biomedicine and the Environment}, booktitle = {Carbon Nanomaterials in Biomedicine and the Environment}, publisher = {Jenny Stanford Publishing}, address = {Singapore}, isbn = {978-981-4800-27-3}, doi = {10.1201/9780429428647-18}, pages = {353 -- 378}, year = {2020}, abstract = {This chapter shows that nanomaterials obtained by high-temperature carbonization of inexpensive plant raw material such as rice husk, grape seeds, and walnut shells can serve as a basis for the production of highly efficient microbial drugs, biodestructors, biosorbents, and biocatalysts, which are promising for the remediation of the ecosystem contaminated with heavy and radioactive metals, oil and oil products. A strong interest in engineering zymology is dictated by the necessity to address the issues of monitoring enzymatic processes, treatment, and diagnosis of a number of common human diseases, environmental pollution, quality control of pharmaceuticals and food. Nanomaterials obtained by high-temperature carbonization of cheap plant raw material such as-rice husks, grape seeds and walnut shells, can serve as a basis for creating of highly effective microbial preparations-biodestructors, biosorbents and biocatalysts, which are promising for the use of contaminated ecosystems, and for restoration of human intestine microecology.}, language = {en} } @inproceedings{ThomaFisherBraun2020, author = {Thoma, Andreas and Fisher, Alex and Braun, Carsten}, title = {Improving the px4 avoid algorithm by bio-inspired flight strategies}, series = {DLRK2020 - „Luft- und Raumfahrt - Verantwortung in allen Dimensionen"}, booktitle = {DLRK2020 - „Luft- und Raumfahrt - Verantwortung in allen Dimensionen"}, doi = {10.25967/530183}, pages = {10 Seiten}, year = {2020}, language = {en} } @inproceedings{EggertStanke2020, author = {Eggert, Mathias and Stanke, Max-Alexander}, title = {Adoption of Integrated Voice Assistants in Health Care- Requirements and Design Guidelines}, publisher = {GITO}, address = {Berlin}, doi = {10.30844/wi_2020_k2-eggert}, pages = {16 Seiten}, year = {2020}, abstract = {Integrated voice assistants (IVA) receive more and more attention and are widespread for entertainment use cases, such as radio hearing or web searches. At the same time, the health care segment suffers in process inefficiency and missing staff, whereas the usage of IVA has the potential to improve caring processes and patient satisfaction. By applying a design science approach and based on a qualitative study, we identify IVA requirements, barriers and design guidelines for the health care sector. The results reveal three important IVA functions: the ability to set appointments with care service staff, the documentation of health history and the communication with service staff. Integration, system stability and volume control are the most important nonfunctional requirements. Based on the interview results and project experiences, six design and implementation guidelines are derived.}, language = {en} } @article{GoettenHavermannBraunetal.2020, author = {G{\"o}tten, Falk and Havermann, Marc and Braun, Carsten and Marino, Matthew and Bil, Cees}, title = {Wind-tunnel and CFD investigations of UAV landing gears and turrets - Improvements in empirical drag estimation}, series = {Aerospace Science and Technology}, volume = {107}, journal = {Aerospace Science and Technology}, number = {Art. 106306}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1270-9638}, doi = {10.1016/j.ast.2020.106306}, year = {2020}, abstract = {This paper analyzes the drag characteristics of several landing gear and turret configurations that are representative of unmanned aircraft tricycle landing gears and sensor turrets. A variety of these components were constructed via 3D-printing and analyzed in a wind-tunnel measurement campaign. Both turrets and landing gears were attached to a modular fuselage that supported both isolated components and multiple components at a time. Selected cases were numerically investigated with a Reynolds-averaged Navier-Stokes approach that showed good accuracy when compared to wind-tunnel data. The drag of main gear struts could be significantly reduced via streamlining their cross-sectional shape and keeping load carrying capabilities similar. The attachment of wheels introduced interference effects that increased strut drag moderately but significantly increased wheel drag compared to isolated cases. Very similar behavior was identified for front landing gears. The drag of an electro-optical and infrared sensor turret was found to be much higher than compared to available data of a clean hemisphere-cylinder combination. This turret drag was merely influenced by geometrical features like sensor surfaces and the rotational mechanism. The new data of this study is used to develop simple drag estimation recommendations for main and front landing gear struts and wheels as well as sensor turrets. These recommendations take geometrical considerations and interference effects into account.}, language = {en} } @book{LabischWaehlisch2020, author = {Labisch, Susanna and W{\"a}hlisch, Georg}, title = {Technisches Zeichnen: Eigenst{\"a}ndig lernen und effektiv {\"u}ben}, edition = {6th ed.}, publisher = {Springer Vieweg}, address = {Wiesbaden}, isbn = {978-3-658-30650-2 (E-Book)}, doi = {10.1007/978-3-658-30650-2}, pages = {Online-Ressource (XI, 296 S. 300 Abb., 81 Abb. in Farbe)}, year = {2020}, language = {de} } @inproceedings{MarinkovicButenweg2020, author = {Marinkovic, Marko and Butenweg, Christoph}, title = {Seismic behaviour of RC frames with uncoupled masonry infills having two storeys or two bays}, series = {Brick and Block Masonry - From Historical to Sustainable Masonry. Proceedings of the 17th International Brick/Block Masonry Conference}, booktitle = {Brick and Block Masonry - From Historical to Sustainable Masonry. Proceedings of the 17th International Brick/Block Masonry Conference}, publisher = {CRC Press}, address = {London}, doi = {10.1201/9781003098508-72}, pages = {1 -- 7}, year = {2020}, abstract = {Reinforced concrete (RC) structures with masonry infills are widely used for several types of buildings all over the world. However, it is well known that traditional masonry infills constructed with rigid contact to the surrounding RC frame performed rather poor in past earthquakes. Masonry infills showed severe in-plane damages and failed in many cases under out-of-plane seismic loading. As the undesired interactions between frames and infills changes the load transfer on building level, complete collapses of buildings were observed. A possible solution is uncoupling of masonry infills to the frame to reduce the infill contribution activated by the frame deformation under horizontal loading. The paper presents numerical simulations on RC frames equipped with the innovative decoupling system INODIS. The system was developed within the European project INSYSME and allows an effective uncoupling of frame and infill. The simulations are carried out with a micro-modelling approach, which is able to predict the complex nonlinear behaviour resulting from the different materials and their interaction. Each brick is modelled individually and connected taking into account nonlinearity of a brick mortar interface. The calibration of the model is based on small specimen tests and experimental results for one bay one storey frame are used for the validation. The validated model is further used for parametric studies on two storey and two bay infilled frames. The response and change of the structural stiffness are analysed and compared to the traditionally infilled frame. The results confirm the effectiveness of the INODIS system with less damage and relatively low contribution of the infill at high drift levels. In contrast to the uncoupled system configurations, traditionally infilled frames experienced brittle failure at rather low drift levels.}, language = {en} } @inproceedings{MichelRosinButenwegetal.2020, author = {Michel, Philipp and Rosin, Julia and Butenweg, Christoph and Klinkel, Sven}, title = {Soil-dependent earthquake spectra in the analysis of liquid-storage-tanks on compliant soil}, series = {Seismic design of industrial facilities 2020}, booktitle = {Seismic design of industrial facilities 2020}, publisher = {Apprimus Verlag}, address = {Aachen}, isbn = {978-3-86359-729-0}, pages = {245 -- 254}, year = {2020}, abstract = {A further development of the Added-Mass-Method allows the combined representation of the effects of both soil-structure-interaction and fluid-structure interaction on a liquid-filled-tank in one model. This results in a practical method for describing the dynamic fluid pressure on the tank shell during joint movement. The fluid pressure is calculated on the basis of the tank's eigenform and the earthquake acceleration and represented by additional masses on the shell. The bearing on compliant ground is represented by replacement springs, which are calculated dependent on the local soil composition. The influence of the shear modulus of the compliant soil is clearly visible in the pressure curves and the stress distribution in the shell. The acceleration spectra are also dependent on soil stiffness. According to Eurocode-8 the acceleration spectra are determined for fixed soil-classes, instead of calculating the accelerations for each site in direct dependence on the soil composition. This leads to unrealistic sudden changes in the system's response. Therefore, earthquake spectra are calculated for different soil models in direct dependence of the shear modulus. Thus, both the acceleration spectra and the replacement springs match the soil composition. This enables a reasonable and consistent calculation of the system response for the actual conditions at each site.}, language = {en} } @inproceedings{MarkinkovicButenwegPaveseetal.2020, author = {Markinkovic, Marko and Butenweg, Christoph and Pavese, A. and Lanese, I. and Hoffmeister, B. and Pinkawa, M. and Vulcu, C. and Bursi, O. and Nardin, C. and Paolacci, F. and Quinci, G. and Fragiadakis, M. and Weber, F. and Huber, P. and Renault, P. and G{\"u}ndel, M. and Dyke, S. and Ciucci, M. and Marino, A.}, title = {Investigation of the seismic behaviour of structural and nonstructural components in industrial facilities by means of shaking table tests}, series = {Seismic design of industrial facilities 2020}, booktitle = {Seismic design of industrial facilities 2020}, publisher = {Apprimus Verlag}, address = {Aachen}, isbn = {978-3-86359-729-0}, pages = {159 -- 172}, year = {2020}, language = {en} } @inproceedings{CacciatoreButenweg2020, author = {Cacciatore, Pamela and Butenweg, Christoph}, title = {Seismic safety of cylindrical granular material steel silos under seismic loading}, series = {Seismic design of industrial facilities 2020}, booktitle = {Seismic design of industrial facilities 2020}, publisher = {Apprimus Verlag}, address = {Aachen}, isbn = {978-3-86359-729-0}, pages = {231 -- 244}, year = {2020}, language = {en} } @article{AkimbekovDigelSherelkhanetal.2020, author = {Akimbekov, Nuraly S. and Digel, Ilya and Sherelkhan, Dinara K. and Lutfor, Afzalunnessa B. and Razzaque, Mohammed S.}, title = {Vitamin D and the Host-Gut Microbiome: A Brief Overview}, series = {Acta Histochemica et Cytochemica}, volume = {53}, journal = {Acta Histochemica et Cytochemica}, number = {3}, publisher = {Japan Society of Histochemistry and Cytochemistry}, address = {Osaka}, issn = {1347-5800}, doi = {10.1267/ahc.20011}, pages = {33 -- 42}, year = {2020}, abstract = {There is a growing body of evidence for the effects of vitamin D on intestinal host-microbiome interactions related to gut dysbiosis and bowel inflammation. This brief review highlights the potential links between vitamin D and gut health, emphasizing the role of vitamin D in microbiological and immunological mechanisms of inflammatory bowel diseases. A comprehensive literature search was carried out in PubMed and Google Scholar using combinations of keywords "vitamin D," "intestines," "gut microflora," "bowel inflammation". Only articles published in English and related to the study topic are included in the review. We discuss how vitamin D (a) modulates intestinal microbiome function, (b) controls antimicrobial peptide expression, and (c) has a protective effect on epithelial barriers in the gut mucosa. Vitamin D and its nuclear receptor (VDR) regulate intestinal barrier integrity, and control innate and adaptive immunity in the gut. Metabolites from the gut microbiota may also regulate expression of VDR, while vitamin D may influence the gut microbiota and exert anti-inflammatory and immune-modulating effects. The underlying mechanism of vitamin D in the pathogenesis of bowel diseases is not fully understood, but maintaining an optimal vitamin D status appears to be beneficial for gut health. Future studies will shed light on the molecular mechanisms through which vitamin D and VDR interactions affect intestinal mucosal immunity, pathogen invasion, symbiont colonization, and antimicrobial peptide expression.}, language = {en} } @article{KoehlerWolf2020, author = {K{\"o}hler, Klemens and Wolf, Martin R.}, title = {Organisatorische Maßnahmen zu Erh{\"o}hung der IT Sicherheit - Empfehlungen aus der Perspektive der Konflikttheorie}, number = {Preprint}, year = {2020}, abstract = {Die NATO definiert den Cyberspace als die "Umgebung, die durch physische und nicht-physische Bestandteile zum Speichern, {\"A}ndern, und Austauschen von Daten mit Hilfe von Computer-Netzwerken" [NATO CCDCOE]. Dar{\"u}ber hinaus ist es ein Medium menschlicher Interaktion. IT Angriffe sind feindselige, nichtkooperative Interaktionen, die mittels Konflikttheorie beschrieben werden k{\"o}nnen. Durch die Anwendung dieses Gedankengeb{\"a}udes auf IT Sicherheit von Organisationen k{\"o}nnen eine Reihe von Verbesserungen in Unternehmen identifiziert werden.}, language = {de} }