@article{Golland2020, author = {Golland, Alexander}, title = {Die Zukunft internationaler Datentransfers: Quo vadis?}, year = {2020}, abstract = {Nach dem Scheitern des Privacy Shield hofft der Datenschutzberater Alexander Golland, dass die europ{\"a}ischen Beh{\"o}rden bald konkrete Maßnahmen f{\"u}r den Datentransfer in Drittl{\"a}nder vorschlagen. Auch kleine Unternehmen m{\"u}ssten die Herausforderung bew{\"a}ltigen - sonst w{\"a}re das Urteil nur Wasser auf die M{\"u}hlen jener, die ohnehin {\"u}ber den Datenschutz schimpfen.}, language = {de} } @incollection{GollandOhrtmann2020, author = {Golland, Alexander and Ohrtmann, Jan-Peter}, title = {Video surveillance: The supervisory authorities' view andrecent case law}, series = {Turning Point in Data Protection Law}, booktitle = {Turning Point in Data Protection Law}, publisher = {Nomos}, address = {Baden-Baden}, isbn = {978-3-8487-6909-4}, doi = {10.5771/9783748921561-175}, pages = {175 -- 178}, year = {2020}, language = {en} } @inproceedings{HauggKreyerKemperetal.2020, author = {Haugg, Albert Thomas and Kreyer, J{\"o}rg and Kemper, Hans and Hatesuer, Katerina and Esch, Thomas}, title = {Heat exchanger for ORC. adaptability and optimisation potentials}, series = {IIR International Rankine 2020 Conference}, booktitle = {IIR International Rankine 2020 Conference}, doi = {10.18462/iir.rankine.2020.1224}, pages = {10 Seiten}, year = {2020}, abstract = {The recovery of waste heat requires heat exchangers to extract it from a liquid or gaseous medium into another working medium, a refrigerant. In Organic Rankine Cycles (ORC) on Combustion Engines there are two major heat sources, the exhaust gas and the water/glycol fluid from the engine's cooling circuit. A heat exchanger design must be adapted to the different requirements and conditions resulting from the heat sources, fluids, system configurations, geometric restrictions, and etcetera. The Stacked Shell Cooler (SSC) is a new and very specific design of a plate heat exchanger, created by AKG, which allows with a maximum degree of freedom the optimization of heat exchange rate and the reduction of the related pressure drop. This optimization in heat exchanger design for ORC systems is even more important, because it reduces the energy consumption of the system and therefore maximizes the increase in overall efficiency of the engine.}, language = {en} } @article{Golland2020, author = {Golland, Alexander}, title = {Datenschutzrechtliche Fragen personalisierter Preise — Herausforderungen von Algorithmen im Schnittbereich von Ethik, {\"O}konomie und Datenschutz}, series = {CR Computer und Recht}, volume = {36}, journal = {CR Computer und Recht}, number = {3}, publisher = {Verlag Dr. Otto Schmidt}, address = {K{\"o}ln}, isbn = {2194-4172}, doi = {10.9785/cr-2020-360313}, pages = {186 -- 194}, year = {2020}, language = {de} } @misc{Golland2020, author = {Golland, Alexander}, title = {Immaterieller Schadensersatz f{\"u}r die Weiterleitung von Daten {\"u}ber ein berufsbezogenes soziales Netzwerk}, series = {DSB Datenschutz-Berater}, volume = {44}, journal = {DSB Datenschutz-Berater}, number = {11}, issn = {0170-7256}, pages = {286 -- 288}, year = {2020}, language = {de} } @misc{Golland2020, author = {Golland, Alexander}, title = {Anspruch gegen einen Suchmaschinenbetreiber auf L{\"o}schung von Suchergebnissen}, series = {ZD Zeitschrift f{\"u}r Datenschutz}, volume = {2020}, journal = {ZD Zeitschrift f{\"u}r Datenschutz}, number = {10}, publisher = {C.H. Beck}, address = {M{\"u}nchen}, issn = {2192-5593}, pages = {531 -- 532}, year = {2020}, language = {de} } @article{Golland2020, author = {Golland, Alexander}, title = {Datenschutzrechtliche Anforderungen an internationale Datentransfers}, series = {NJW - Neue Juristische Wochenschrift}, volume = {2020}, journal = {NJW - Neue Juristische Wochenschrift}, number = {36}, publisher = {Beck}, address = {M{\"u}nchen}, issn = {0341-1915}, pages = {2593 -- 2596}, year = {2020}, language = {de} } @misc{Golland2020, author = {Golland, Alexander}, title = {Rezension zu: Sydow - Bundesdatenschutzgesetz, Handkommentar (2020)}, series = {DSB Datenschutz-Berater}, volume = {44}, journal = {DSB Datenschutz-Berater}, number = {3}, issn = {0170-7256}, pages = {76 -- 76}, year = {2020}, language = {de} } @misc{Golland2020, author = {Golland, Alexander}, title = {Rezension zu: Spiecker gen. D{\"o}hmann/Bretthauer - Dokumentation zum Datenschutz (2019)}, series = {DSB Datenschutz-Berater}, volume = {44}, journal = {DSB Datenschutz-Berater}, number = {2}, issn = {0170-7256}, pages = {52 -- 52}, year = {2020}, language = {de} } @incollection{Golland2020, author = {Golland, Alexander}, title = {Struggling with users' consent: Economic approach to solve the issue of coupling}, series = {Turning Point in Data Protection Law}, booktitle = {Turning Point in Data Protection Law}, publisher = {Nomos}, address = {Baden-Baden}, isbn = {978-3-8487-6909-4}, doi = {10.5771/9783748921561-121}, pages = {121 -- 126}, year = {2020}, language = {en} } @article{Golland2020, author = {Golland, Alexander}, title = {Die „private" Datenverarbeitung im Internet. Verantwortlichkeiten und Rechtm{\"a}ßigkeit bei Nutzung von Plattformdiensten durch nat{\"u}rliche Personen}, series = {ZD Zeitschrift f{\"u}r Datenschutz}, volume = {10}, journal = {ZD Zeitschrift f{\"u}r Datenschutz}, number = {8}, editor = {Hoeren, Thomas and Schneider, Jochen and Selmayr, Martin and Spies, Axel and Wybitul, Tim}, publisher = {Beck}, address = {M{\"u}nchen}, isbn = {2192-5593}, pages = {397 -- 403}, year = {2020}, language = {de} } @article{Golland2020, author = {Golland, Alexander}, title = {Weckruf f{\"u}r deutsche Großunternehmen? - Der neue Entwurf des IT-Sicherheitsgesetz 2.0}, series = {K\&R Kommunikation \& Recht}, volume = {23}, journal = {K\&R Kommunikation \& Recht}, number = {7-8}, publisher = {dfv Mediengruppe}, address = {Frankfurt a.M.}, isbn = {1434-6354}, pages = {I}, year = {2020}, language = {de} } @article{Golland2020, author = {Golland, Alexander}, title = {EDPB: Europ{\"a}ische Aufsichtsbeh{\"o}rden mit neuen Guidelines zur datenschutzkonformen Einwilligung}, series = {DSB Datenschutz-Berater}, volume = {44}, journal = {DSB Datenschutz-Berater}, number = {6}, publisher = {dfv Mediengruppe}, address = {Frankfurt a.M.}, isbn = {0170-7256}, pages = {151 -- 153}, year = {2020}, language = {de} } @article{Golland2020, author = {Golland, Alexander}, title = {Verantwortlichkeit, Data Breach, das Ende von Fax \& E-Mail: Aufsichtsbeh{\"o}rden mit streitbaren Thesen}, series = {DSB Datenschutz-Berater}, volume = {44}, journal = {DSB Datenschutz-Berater}, number = {4}, publisher = {dfv Mediengruppe}, address = {Frankfurt a.M.}, isbn = {0170-7256}, pages = {98 -- 100}, year = {2020}, language = {de} } @inproceedings{LorenzAltherrPelz2020, author = {Lorenz, Imke-Sophie and Altherr, Lena and Pelz, Peter F.}, title = {Resilience enhancement of critical infrastructure - graph-theoretical resilience analysis of the water distribution system in the German city of Darmstadt}, series = {14th WCEAM Proceedings}, booktitle = {14th WCEAM Proceedings}, publisher = {Springer}, address = {Cham}, isbn = {978-3-030-64228-0}, doi = {10.1007/978-3-030-64228-0_13}, pages = {137 -- 149}, year = {2020}, abstract = {Water suppliers are faced with the great challenge of achieving high-quality and, at the same time, low-cost water supply. Since climatic and demographic influences will pose further challenges in the future, the resilience enhancement of water distribution systems (WDS), i.e. the enhancement of their capability to withstand and recover from disturbances, has been in particular focus recently. To assess the resilience of WDS, graph-theoretical metrics have been proposed. In this study, a promising approach is first physically derived analytically and then applied to assess the resilience of the WDS for a district in a major German City. The topology based resilience index computed for every consumer node takes into consideration the resistance of the best supply path as well as alternative supply paths. This resistance of a supply path is derived to be the dimensionless pressure loss in the pipes making up the path. The conducted analysis of a present WDS provides insight into the process of actively influencing the resilience of WDS locally and globally by adding pipes. The study shows that especially pipes added close to the reservoirs and main branching points in the WDS result in a high resilience enhancement of the overall WDS.}, language = {en} } @article{CzarneckiDietze2020, author = {Czarnecki, Christian and Dietze, Christian}, title = {Gestaltungsorientierte Forschung am Beispiel der Referenzmodellierung in der Telekommunikationsindustrie}, series = {HMD Praxis der Wirtschaftsinformatik}, volume = {57}, journal = {HMD Praxis der Wirtschaftsinformatik}, number = {2}, publisher = {Springer Nature}, address = {Cham}, issn = {2198-2775}, doi = {10.1365/s40702-020-00594-y}, pages = {310 -- 323}, year = {2020}, abstract = {Am Beispiel der Telekommunikationsindustrie zeigt der Beitrag eine konkrete Ausgestaltung anwendungsorientierter Forschung, die sowohl f{\"u}r die Praxis als auch f{\"u}r die Wissenschaft nutzen- und erkenntnisbringend ist. Forschungsgegenstand sind die Referenzmodelle des Industriegremiums TM Forum, die von vielen Telekommunikationsunternehmen zur Transformation ihrer Strukturen und Systeme genutzt werden. Es wird die langj{\"a}hrige Forschungst{\"a}tigkeit bei der Weiterentwicklung und Anwendung dieser Referenzmodelle beschrieben. Dabei wird ein konsequent gestaltungsorientierter Forschungsansatz verfolgt. Das Zusammenspiel aus kontinuierlicher Weiterentwicklung in Zusammenarbeit mit einem Industriegremium und der Anwendung in vielf{\"a}ltigen Praxisprojekten f{\"u}hrt zu einer erfolgreichen Symbiose aus praktischer Nutzengenerierung sowie wissenschaftlichem Erkenntnisgewinn. Der Beitrag stellt den gew{\"a}hlten Forschungsansatz anhand konkreter Beispiele vor. Darauf basierend werden Empfehlungen und Herausforderungen f{\"u}r eine gestaltungs- und praxisorientierte Forschung diskutiert.}, language = {de} } @misc{OPUS4-10313, title = {Dimensionen 1-2020: Magazin der FH Aachen University of Applied Sciences - Bibliotheken im 21. Jahrhundert}, address = {Aachen}, organization = {Fachhochschule Aachen}, pages = {47 Seiten}, year = {2020}, abstract = {04| Wissen stirbt nicht aus 12| Mathe ist sexy! 15| „Bei Gr{\"u}n bitte mit Abstand eintreten" 16| Maschinenbau — mehr als nur Metall 17| Brasilianischer Doktorand der zweiten Generation 18| Aus Alt mach Neu 20| Virtuelle Verleihung 21| Ehrenvolle Auszeichnung 22| Mit Regenjacke und Gummistiefeln 24| Ein Herz aus Beton 27| Wissenstransfer f{\"u}r die Automobilindustrie 28| Mission zum Mond 30| Eine Br{\"u}cke, die sich selbst {\"u}berwacht 32| Licht an — Kanal frei 34| Ein Tropfen auf den heißen Stein 36| Ist ein Studium das Richtige f{\"u}r mich? 38| Himmelblau und Feuerrot 41| Kopfnuss 41| Impressum 42| Mit Leichtigkeit und Transparenz 46| Dialektik des Stillstands}, language = {de} } @incollection{SchneiderWisselinkNoelleetal.2020, author = {Schneider, Dominik and Wisselink, Frank and N{\"o}lle, Nikolai and Czarnecki, Christian}, title = {Influence of artificial intelligence on commercial interactions in the consumer market}, series = {Automatisierung und Personalisierung von Dienstleistungen : Methoden - Potenziale - Einsatzfelder}, booktitle = {Automatisierung und Personalisierung von Dienstleistungen : Methoden - Potenziale - Einsatzfelder}, editor = {Bruhn, Manfred and Hadwich, Karsten}, publisher = {Springer Gabler}, address = {Wiesbaden}, isbn = {978-3-658-30167-5 (Print)}, doi = {10.1007/978-3-658-30168-2_7}, pages = {183 -- 205}, year = {2020}, abstract = {Recently, novel AI-based services have emerged in the consumer market. AI-based services can affect the way consumers take commercial decisions. Research on the influence of AI on commercial interactions is in its infancy. In this chapter, a framework creating a first overview of the influence of AI on commercial interactions is introduced. This framework summarizes the findings of comparing numerous customer journeys of novel AI-based services with corresponding non-AI equivalents.}, language = {en} } @misc{Czarnecki2020, author = {Czarnecki, Christian}, title = {Buchbesprechung : Anwendungsorientierte Wirtschaftsinformatik - Strategische Planung, Entwicklung und Nutzung von Informationssystemen}, series = {Anwendungen und Konzepte der Wirtschaftsinformatik (AKWI-Journal)}, journal = {Anwendungen und Konzepte der Wirtschaftsinformatik (AKWI-Journal)}, publisher = {Technische Hochschule Wildau}, address = {Wildau}, issn = {2296-4592}, doi = {10.26034/lu.akwi.2020.3264}, pages = {101 -- 101}, year = {2020}, language = {de} } @article{BensbergAuthCzarnecki2020, author = {Bensberg, Frank and Auth, Gunnar and Czarnecki, Christian}, title = {Literaturanalyse mit Text Mining}, series = {E-Learning and Education (eleed)}, journal = {E-Learning and Education (eleed)}, number = {13}, editor = {Haake, J{\"o}rg M.}, publisher = {FernUniversit{\"a}t in Hagen}, address = {Hagen}, issn = {1860-7470}, pages = {1 -- 13}, year = {2020}, abstract = {Die Durchf{\"u}hrung einer systematischen Literaturrecherche ist eine zentrale Kompetenz wissenschaftlichen Arbeitens und bildet daher einen festen Ausbildungsbestandteil von Bachelor- und Masterstudieng{\"a}ngen. In entsprechenden Lehrveranstaltungen werden Studierende zwar mit den grundlegenden Hilfsmitteln zur Suche und Verwaltung von Literatur vertraut gemacht, allerdings werden die Potenziale textanalytischer Methoden und Anwendungssysteme (Text Mining, Text Analytics) dabei zumeist nicht abgedeckt. Folglich werden Datenkompetenzen, die zur systemgest{\"u}tzten Analyse und Erschließung von Literaturdaten erforderlich sind, nicht hinreichend ausgepr{\"a}gt. Um diese Kompetenzl{\"u}cke zu adressieren, ist an der Hochschule Osnabr{\"u}ck eine Lehrveranstaltung konzipiert und projektorientiert umgesetzt worden, die sich insbesondere an Studierende wirtschaftswissenschaftlicher Studieng{\"a}nge richtet. Dieser Beitrag dokumentiert die fachliche sowie technische Ausgestaltung dieser Veranstaltung und zeigt Potenziale f{\"u}r die k{\"u}nftige Weiterentwicklung auf.}, language = {de} } @inproceedings{KirschMatareFerreinetal.2020, author = {Kirsch, Maximilian and Matar{\´e}, Victor and Ferrein, Alexander and Schiffer, Stefan}, title = {Integrating golog++ and ROS for Practical and Portable High-level Control}, series = {12th International Conference on Agents and Artificial Intelligence}, booktitle = {12th International Conference on Agents and Artificial Intelligence}, doi = {10.5220/0008984406920699}, year = {2020}, language = {en} } @article{DantismRoehlenDahmenetal.2020, author = {Dantism, Shahriar and R{\"o}hlen, Desiree and Dahmen, Markus and Wagner, Torsten and Wagner, Patrick and Sch{\"o}ning, Michael Josef}, title = {LAPS-based monitoring of metabolic responses of bacterial cultures in a paper fermentation broth}, series = {Sensors and Actuators B: Chemical}, volume = {320}, journal = {Sensors and Actuators B: Chemical}, number = {Art. 128232}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0925-4005}, doi = {10.1016/j.snb.2020.128232}, year = {2020}, abstract = {As an alternative renewable energy source, methane production in biogas plants is gaining more and more attention. Biomass in a bioreactor contains different types of microorganisms, which should be considered in terms of process-stability control. Metabolically inactive microorganisms within the fermentation process can lead to undesirable, time-consuming and cost-intensive interventions. Hence, monitoring of the cellular metabolism of bacterial populations in a fermentation broth is crucial to improve the biogas production, operation efficiency, and sustainability. In this work, the extracellular acidification of bacteria in a paper-fermentation broth is monitored after glucose uptake, utilizing a differential light-addressable potentiometric sensor (LAPS) system. The LAPS system is loaded with three different model microorganisms (Escherichia coli, Corynebacterium glutamicum, and Lactobacillus brevis) and the effect of the fermentation broth at different process stages on the metabolism of these bacteria is studied. In this way, different signal patterns related to the metabolic response of microorganisms can be identified. By means of calibration curves after glucose uptake, the overall extracellular acidification of bacterial populations within the fermentation process can be evaluated.}, language = {en} } @article{HueningDeMatteis2020, author = {H{\"u}ning, Felix and De Matteis, Stefan}, title = {Entwicklung eines taktilen HMI f{\"u}r sehbehinderte und blinde Nutzerinnen und Nutzer}, series = {Blind - sehbehindert}, volume = {140}, journal = {Blind - sehbehindert}, number = {2}, publisher = {Edition Bentheim}, address = {W{\"u}rzburg}, issn = {0176-7836}, pages = {9 -- 19}, year = {2020}, language = {de} } @article{BayerTemizArtmannDigeletal.2020, author = {Bayer, Robin and Temiz Artmann, Ayseg{\"u}l and Digel, Ilya and Falkenstein, Julia and Artmann, Gerhard and Creutz, Till and Hescheler, J{\"u}rgen}, title = {Mechano-pharmacological testing of L-Type Ca²⁺ channel modulators via human vascular celldrum model}, series = {Cellular Physiology and Biochemistry}, volume = {54}, journal = {Cellular Physiology and Biochemistry}, publisher = {Cell Physiol Biochem Press}, address = {D{\"u}sseldorf}, issn = {1421-9778}, doi = {10.33594/000000225}, pages = {371 -- 383}, year = {2020}, abstract = {Background/Aims: This study aimed to establish a precise and well-defined working model, assessing pharmaceutical effects on vascular smooth muscle cell monolayer in-vitro. It describes various analysis techniques to determine the most suitable to measure the biomechanical impact of vasoactive agents by using CellDrum technology. Methods: The so-called CellDrum technology was applied to analyse the biomechanical properties of confluent human aorta muscle cells (haSMC) in monolayer. The cell generated tensions deviations in the range of a few N/m² are evaluated by the CellDrum technology. This study focuses on the dilative and contractive effects of L-type Ca²⁺ channel agonists and antagonists, respectively. We analyzed the effects of Bay K8644, nifedipine and verapamil. Three different measurement modes were developed and applied to determine the most appropriate analysis technique for the study purpose. These three operation modes are called, particular time mode" (PTM), "long term mode" (LTM) and "real-time mode" (RTM). Results: It was possible to quantify the biomechanical response of haSMCs to the addition of vasoactive agents using CellDrum technology. Due to the supplementation of 100nM Bay K8644, the tension increased approximately 10.6\% from initial tension maximum, whereas, the treatment with nifedipine and verapamil caused a significant decrease in cellular tension: 10nM nifedipine decreased the biomechanical stress around 6,5\% and 50nM verapamil by 2,8\%, compared to the initial tension maximum. Additionally, all tested measurement modes provide similar results while focusing on different analysis parameters. Conclusion: The CellDrum technology allows highly sensitive biomechanical stress measurements of cultured haSMC monolayers. The mechanical stress responses evoked by the application of vasoactive calcium channel modulators were quantified functionally (N/m²). All tested operation modes resulted in equal findings, whereas each mode features operation-related data analysis.}, language = {en} } @article{RichterWichernGroempingetal.2020, author = {Richter, L. and Wichern, M. and Gr{\"o}mping, Markus and Robecke, U. and Haberkamp, J.}, title = {Ammonium recovery from process water of digested sludge dewatering by membrane contactors}, series = {Water Practice and Technology}, volume = {15}, journal = {Water Practice and Technology}, number = {1}, publisher = {IWA Publishing}, address = {London}, issn = {1751-231X}, doi = {10.2166/wpt.2020.002}, pages = {84 -- 91}, year = {2020}, abstract = {Membrane contactors are a promising alternative for nitrogen removal and recovery from process water compared to other physicochemical and biological sidestream treatment processes. M{\"u}nster wastewater treatment plant (WWTP) is the first municipal WWTP in Germany operating a full-scale membrane contactor system to improve the nitrogen elimination and recovery efficiency. Factors influencing the operation and membrane performance are investigated in an accompanying research project. Additional operational aspects of the applied membrane modules are investigated in detail using a bench-scale membrane contactor. First results of the full-scale application demonstrate a high nitrogen removal efficiency of >95\%.}, language = {de} } @article{FingerGoettenBraunetal.2020, author = {Finger, Felix and G{\"o}tten, Falk and Braun, Carsten and Bil, Cees}, title = {Mass, primary energy, and cost: the impact of optimization objectives on the initial sizing of hybrid-electric general aviation aircraft}, series = {CEAS Aeronautical Journal}, volume = {2020}, journal = {CEAS Aeronautical Journal}, number = {11}, publisher = {Springer}, address = {Heidelberg}, issn = {1869-5590}, doi = {10.1007/s13272-020-00449-8}, pages = {713 -- 730}, year = {2020}, abstract = {For short take-off and landing (STOL) aircraft, a parallel hybrid-electric propulsion system potentially offers superior performance compared to a conventional propulsion system, because the short-take-off power requirement is much higher than the cruise power requirement. This power-matching problem can be solved with a balanced hybrid propulsion system. However, there is a trade-off between wing loading, power loading, the level of hybridization, as well as range and take-off distance. An optimization method can vary design variables in such a way that a minimum of a particular objective is attained. In this paper, a comparison between the optimization results for minimum mass, minimum consumed primary energy, and minimum cost is conducted. A new initial sizing algorithm for general aviation aircraft with hybrid-electric propulsion systems is applied. This initial sizing methodology covers point performance, mission performance analysis, the weight estimation process, and cost estimation. The methodology is applied to the design of a STOL general aviation aircraft, intended for on-demand air mobility operations. The aircraft is sized to carry eight passengers over a distance of 500 km, while able to take off and land from short airstrips. Results indicate that parallel hybrid-electric propulsion systems must be considered for future STOL aircraft.}, language = {en} } @article{EggertAlberts2020, author = {Eggert, Mathias and Alberts, Jens}, title = {Frontiers of business intelligence and analytics 3.0: a taxonomy-based literature review and research agenda}, series = {Business Research}, volume = {2020}, journal = {Business Research}, number = {13}, publisher = {Springer}, address = {Heidelberg}, issn = {2198-2627}, doi = {10.1007/s40685-020-00108-y}, pages = {685 -- 739}, year = {2020}, abstract = {Researching the field of business intelligence and analytics (BI \& A) has a long tradition within information systems research. Thereby, in each decade the rapid development of technologies opened new room for investigation. Since the early 1950s, the collection and analysis of structured data were the focus of interest, followed by unstructured data since the early 1990s. The third wave of BI \& A comprises unstructured and sensor data of mobile devices. The article at hand aims at drawing a comprehensive overview of the status quo in relevant BI \& A research of the current decade, focusing on the third wave of BI \& A. By this means, the paper's contribution is fourfold. First, a systematically developed taxonomy for BI \& A 3.0 research, containing seven dimensions and 40 characteristics, is presented. Second, the results of a structured literature review containing 75 full research papers are analyzed by applying the developed taxonomy. The analysis provides an overview on the status quo of BI \& A 3.0. Third, the results foster discussions on the predicted and observed developments in BI \& A research of the past decade. Fourth, research gaps of the third wave of BI \& A research are disclosed and concluded in a research agenda.}, language = {en} } @article{QuittmannAbelAlbrachtetal.2020, author = {Quittmann, Oliver J. and Abel, Thomas and Albracht, Kirsten and Meskemper, Joshua and Foitschik, Tina and Str{\"u}der, Heiko K.}, title = {Biomechanics of handcycling propulsion in a 30-min continuous load test at lactate threshold: Kinetics, kinematics, and muscular activity in able-bodied participants}, series = {European Journal of Applied Physiology}, journal = {European Journal of Applied Physiology}, number = {120}, publisher = {Springer}, address = {Heidelberg}, issn = {1439-6327}, doi = {10.1007/s00421-020-04373-x}, pages = {1403 -- 1415}, year = {2020}, abstract = {Purpose This study aims to investigate the biomechanics of handcycling during a continuous load trial (CLT) to assess the mechanisms underlying fatigue in upper body exercise. Methods Twelve able-bodied triathletes performed a 30-min CLT at a power output corresponding to lactate threshold in a racing recumbent handcycle mounted on a stationary ergometer. During the CLT, ratings of perceived exertion (RPE), tangential crank kinetics, 3D joint kinematics, and muscular activity of ten muscles of the upper extremity and trunk were examined using motion capturing and surface electromyography. Results During the CLT, spontaneously chosen cadence and RPE increased, whereas crank torque decreased. Rotational work was higher during the pull phase. Peripheral RPE was higher compared to central RPE. Joint range of motion decreased for elbow-flexion and radial-duction. Integrated EMG (iEMG) increased in the forearm flexors, forearm extensors, and M. deltoideus (Pars spinalis). An earlier onset of activation was found for M. deltoideus (Pars clavicularis), M. pectoralis major, M. rectus abdominis, M. biceps brachii, and the forearm flexors. Conclusion Fatigue-related alterations seem to apply analogously in handcycling and cycling. The most distal muscles are responsible for force transmission on the cranks and might thus suffer most from neuromuscular fatigue. The findings indicate that peripheral fatigue (at similar lactate values) is higher in handcycling compared to leg cycling, at least for inexperienced participants. An increase in cadence might delay peripheral fatigue by a reduced vascular occlusion. We assume that the gap between peripheral and central fatigue can be reduced by sport-specific endurance training.}, language = {en} } @inproceedings{PohleFroehlichDalitzRichteretal.2020, author = {Pohle-Fr{\"o}hlich, Regina and Dalitz, Christoph and Richter, Charlotte and Hahnen, Tobias and St{\"a}udle, Benjamin and Albracht, Kirsten}, title = {Estimation of muscle fascicle orientation in ultrasonic images}, series = {VISIGRAPP 2020 - Proceedings of the 15th International Joint Conference on Computer Vision, Imaging and Computer Graphics Theory and Applications, 5}, booktitle = {VISIGRAPP 2020 - Proceedings of the 15th International Joint Conference on Computer Vision, Imaging and Computer Graphics Theory and Applications, 5}, pages = {79 -- 86}, year = {2020}, language = {en} } @article{KnoxBruggemannGossmannetal.2020, author = {Knox, Ronald and Bruggemann, Andrea and Gossmann, Matthias and Thomas, Ulrich and Horv{\´a}th, Andr{\´a}s and Dragicevic, Elena and Stoelzle-Feix, Sonja and Fertig, Niels and Jung, Alexander and Raman, Aravind Hariharan and Staat, Manfred and Linder, Peter}, title = {Combining physiological relevance and throughput for in vitro cardiac contractility measurement}, series = {Biophysical Journal}, volume = {118}, journal = {Biophysical Journal}, number = {Issue 3, Supplement 1}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0006-3495}, doi = {10.1016/j.bpj.2019.11.3104}, pages = {570a}, year = {2020}, abstract = {Despite increasing acceptance of human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) in safety pharmacology, controversy remains about the physiological relevance of existing in vitro models for their mechanical testing. We hypothesize that existing signs of immaturity of the cell models result from an improper mechanical environment. We cultured hiPSC-CMs in a 96-well format on hyperelastic silicone membranes imitating their native mechanical environment, resulting in physiological responses to compound stimuli.We validated cell responses on the FLEXcyte 96, with a set of reference compounds covering a broad range of cellular targets, including ion channel modulators, adrenergic receptor modulators and kinase inhibitors. Acute (10 - 30 min) and chronic (up to 7 days) effects were investigated. Furthermore, the measurements were complemented with electromechanical models based on electrophysiological recordings of the used cell types.hiPSC-CMs were cultured on freely-swinging, ultra-thin and hyperelastic silicone membranes. The weight of the cell culture medium deflects the membranes downwards. Rhythmic contraction of the hiPSC-CMs resulted in dynamic deflection changes which were quantified by capacitive distance sensing. The cells were cultured for 7 days prior to compound addition. Acute measurements were conducted 10-30 minutes after compound addition in standard culture medium. For chronic treatment, compound-containing medium was replaced daily for up to 7 days. Electrophysiological properties of the employed cell types were recorded by automated patch-clamp (Patchliner) and the results were integrated into the electromechanical model of the system.Calcium channel agonist S Bay K8644 and beta-adrenergic stimulator isoproterenol induced significant positive inotropic responses without additional external stimulation. Kinase inhibitors displayed cardiotoxic effects on a functional level at low concentrations. The system-integrated analysis detected alterations in beating shape as well as frequency and arrhythmic events and we provide a quantitative measure of these.}, language = {en} } @article{VoegeleGrajewskiGovorukhaetal.2020, author = {V{\"o}gele, Stefan and Grajewski, Matthias and Govorukha, Kristina and R{\"u}bbelke, Dirk}, title = {Challenges for the European steel industry: Analysis, possible consequences and impacts on sustainable development}, series = {Applied Energy}, volume = {264}, journal = {Applied Energy}, number = {Article number: 114633}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0306-2619}, doi = {10.1016/j.apenergy.2020.114633}, year = {2020}, abstract = {The steel industry in the European Union (EU), important for the economy as a whole, faces various challenges. These are inter alia volatile prices for relevant input factors, uncertainties concerning the regulation of CO₂-emissions and market shocks caused by the recently introduced additional import duties in the US, which is an important sales market. We examine primary and secondary effects of these challenges on the steel industry in the EU and their impacts on European and global level. Developing and using a suitable meta-model, we analyze the competitiveness of key steel producing countries with respect to floor prices depending on selected cost factors and draw conclusions on the impacts in the trade of steel on emissions, energy demand, on the involvement of developing countries in the value chain as well on the need for innovations to avoid relocations of production. Hence, our study contributes to the assessment of sustainable industrial development, which is aimed by the Sustainability Development Goal "Build resilient infrastructure, promote inclusive and sustainable industrialization and foster innovation countries". By applying information on country-specific Human Development Indexes (reflecting aspects of life expectancy, education, and per capita income), we show that relocating energy-intensive industries from the EU may not only increase global energy demand and CO₂-emissions, but may also be to the disadvantage of developing countries.}, language = {en} } @inproceedings{Laack2020, author = {Laack, Walter van}, title = {Schnittstelle Tod: Aufbruch oder Ende - Kontakte oder Hirngespinste?}, publisher = {van Laack GmbH}, address = {Aachen}, isbn = {978-3-936624-51-9}, pages = {264 Seiten}, year = {2020}, abstract = {Tagungsbeitr{\"a}ge des 6. Europ{\"a}ischen Seminars am 09. November 2019 in Aachen zum Thema Nahtoderfahrungen mit dem Serientitel: "Schnittstelle Tod"}, language = {de} } @incollection{AzatKerimkulovaMansurovetal.2020, author = {Azat, Seitkhan and Kerimkulova, Almagul R. and Mansurov, Zulkhair A. and Adekenov, Sergazy and Artmann, Gerhard}, title = {The Use of Fusicoccin as Anticancer Compound}, series = {Carbon Nanomaterials in Biomedicine and the Environment}, booktitle = {Carbon Nanomaterials in Biomedicine and the Environment}, publisher = {Jenny Stanford Publishing}, address = {New York}, isbn = {978-0-429-42864-7}, doi = {10.1201/9780429428647-8}, pages = {149 -- 172}, year = {2020}, abstract = {The problem of creation and use of sorption materials is of current interest for the practice of the modern medicine and agriculture. Practical importance is production of a biostimulant using a carbon sorbent for a significant increase in productivity, which is very relevant for the regions of Kazakhstan. It is known that a plant phytohormone—fusicoccin—in nanogram concentrations transforms cancer cells to the state of apoptosis. In this regard, there is a scientific practical interest in the development of a highly efficient method for producing fusicoccin from extract of germinated wheat seeds. According to the results of computer modeling, cleaning composite components of fusicoccin using microporous carbon adsorbents not suitable as the size of the molecule of fusicoccin more than micropores and the optimum pore size for purification of constituents of fusicoccin was determined by computer simulation.}, language = {en} } @article{CosmaKesslerGebhardtetal.2020, author = {Cosma, Cosmin and Kessler, Julia and Gebhardt, Andreas and Campbell, Ian and Balc, Nicolae}, title = {Improving the Mechanical Strength of Dental Applications and Lattice Structures SLM Processed}, series = {Materials}, volume = {13}, journal = {Materials}, number = {4}, publisher = {MDPI}, address = {Basel}, issn = {1996-1944}, doi = {10.3390/ma13040905}, pages = {1 -- 18}, year = {2020}, abstract = {To manufacture custom medical parts or scaffolds with reduced defects and high mechanical characteristics, new research on optimizing the selective laser melting (SLM) parameters are needed. In this work, a biocompatible powder, 316L stainless steel, is characterized to understand the particle size, distribution, shape and flowability. Examination revealed that the 316L particles are smooth, nearly spherical, their mean diameter is 39.09 μm and just 10\% of them hold a diameter less than 21.18 μm. SLM parameters under consideration include laser power up to 200 W, 250-1500 mm/s scanning speed, 80 μm hatch spacing, 35 μm layer thickness and a preheated platform. The effect of these on processability is evaluated. More than 100 samples are SLM-manufactured with different process parameters. The tensile results show that is possible to raise the ultimate tensile strength up to 840 MPa, adapting the SLM parameters for a stable processability, avoiding the technological defects caused by residual stress. Correlating with other recent studies on SLM technology, the tensile strength is 20\% improved. To validate the SLM parameters and conditions established, complex bioengineering applications such as dental bridges and macro-porous grafts are SLM-processed, demonstrating the potential to manufacture medical products with increased mechanical resistance made of 316L.}, language = {en} } @article{RuppRiekeHandschuhetal.2020, author = {Rupp, Matthias and Rieke, Christian and Handschuh, Nils and Kuperjans, Isabel}, title = {Economic and ecological optimization of electric bus charging considering variable electricity prices and CO₂eq intensities}, series = {Transportation Research Part D: Transport and Environment}, volume = {81}, journal = {Transportation Research Part D: Transport and Environment}, number = {Article 102293}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1361-9209}, doi = {10.1016/j.trd.2020.102293}, year = {2020}, abstract = {In many cities, diesel buses are being replaced by electric buses with the aim of reducing local emissions and thus improving air quality. The protection of the environment and the health of the population is the highest priority of our society. For the transport companies that operate these buses, not only ecological issues but also economic issues are of great importance. Due to the high purchase costs of electric buses compared to conventional buses, operators are forced to use electric vehicles in a targeted manner in order to ensure amortization over the service life of the vehicles. A compromise between ecology and economy must be found in order to both protect the environment and ensure economical operation of the buses. In this study, we present a new methodology for optimizing the vehicles' charging time as a function of the parameters CO₂eq emissions and electricity costs. Based on recorded driving profiles in daily bus operation, the energy demands of conventional and electric buses are calculated for the passenger transportation in the city of Aachen in 2017. Different charging scenarios are defined to analyze the influence of the temporal variability of CO₂eq intensity and electricity price on the environmental impact and economy of the bus. For every individual day of a year, charging periods with the lowest and highest costs and emissions are identified and recommendations for daily bus operation are made. To enable both the ecological and economical operation of the bus, the parameters of electricity price and CO₂ are weighted differently, and several charging periods are proposed, taking into account the priorities previously set. A sensitivity analysis is carried out to evaluate the influence of selected parameters and to derive recommendations for improving the ecological and economic balance of the battery-powered electric vehicle. In all scenarios, the optimization of the charging period results in energy cost savings of a maximum of 13.6\% compared to charging at a fixed electricity price. The savings potential of CO₂eq emissions is similar, at 14.9\%. From an economic point of view, charging between 2 a.m. and 4 a.m. results in the lowest energy costs on average. The CO₂eq intensity is also low in this period, but midday charging leads to the largest savings in CO₂eq emissions. From a life cycle perspective, the electric bus is not economically competitive with the conventional bus. However, from an ecological point of view, the electric bus saves on average 37.5\% CO₂eq emissions over its service life compared to the diesel bus. The reduction potential is maximized if the electric vehicle exclusively consumes electricity from solar and wind power.}, language = {en} } @inproceedings{FingerdeVriesVosetal.2020, author = {Finger, Felix and de Vries, Reynard and Vos, Roelof and Braun, Carsten and Bil, Cees}, title = {A comparison of hybrid-electric aircraft sizing methods}, series = {AIAA Scitech 2020 Forum}, booktitle = {AIAA Scitech 2020 Forum}, doi = {10.2514/6.2020-1006}, pages = {31 Seiten}, year = {2020}, language = {en} } @article{SmithKotliarLammertynetal.2020, author = {Smith, Wayne and Kotliar, Konstantin and Lammertyn, Leandi and Ramoshaba, Nthai E. and Vilser, Walthard and Huisman, Hugo W. and Schutte, Aletta E.}, title = {Retinal vessel caliber and caliber responses in true normotensive black and white adults: The African-PREDICT study}, series = {Microvascular Research}, volume = {128}, journal = {Microvascular Research}, number = {Article 103937}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0026-2862}, doi = {10.1016/j.mvr.2019.103937}, year = {2020}, abstract = {Purpose Globally, a detrimental shift in cardiovascular disease risk factors and a higher mortality level are reported in some black populations. The retinal microvasculature provides early insight into the pathogenesis of systemic vascular diseases, but it is unclear whether retinal vessel calibers and acute retinal vessel functional responses differ between young healthy black and white adults. Methods We included 112 black and 143 white healthy normotensive adults (20-30 years). Retinal vessel calibers (central retinal artery and vein equivalent (CRAE and CRVE)) were calculated from retinal images and vessel caliber responses to flicker light induced provocation (FLIP) were determined. Additionally, ambulatory blood pressure (BP), anthropometry and blood samples were collected. Results The groups displayed similar 24 h BP profiles and anthropometry (all p > .24). Black participants demonstrated a smaller CRAE (158 ± 11 vs. 164 ± 11 MU, p < .001) compared to the white group, whereas CRVE was similar (p = .57). In response to FLIP, artery maximal dilation was greater in the black vs. white group (5.6 ± 2.1 vs. 3.3 ± 1.8\%; p < .001). Conclusions Already at a young age, healthy black adults showed narrower retinal arteries relative to the white population. Follow-up studies are underway to show if this will be related to increased risk for hypertension development. The reason for the larger vessel dilation responses to FLIP in the black population is unclear and warrants further investigation.}, language = {en} } @article{StreeseKotliarDeiserothetal.2020, author = {Streese, Lukas and Kotliar, Konstantin and Deiseroth, Arne and Infanger, Denis and Gugleta, Konstantin and Schmaderer, Christoph and Hanssen, Henner}, title = {Retinal endothelial function in cardiovascular risk patients: A randomized controlled exercise trial}, series = {Scandinavian Journal of Medicine and Science in Sports}, volume = {30}, journal = {Scandinavian Journal of Medicine and Science in Sports}, number = {2}, publisher = {Wiley}, address = {Oxford}, issn = {1600-0838}, doi = {10.1111/sms.13560}, pages = {272 -- 280}, year = {2020}, abstract = {The aim of this study was to investigate, for the first time, the effects of high-intensity interval training (HIIT) on retinal microvascular endothelial function in cardiovascular (CV) risk patients. In the randomized controlled trial, middle-aged and previously sedentary patients with increased CV risk (aged 58 ± 6 years) with ≥ two CV risk factors were randomized into a 12-week HIIT (n = 33) or control group (CG, n = 36) with standard physical activity recommendations. A blinded examiner measured retinal endothelial function by flicker light-induced maximal arteriolar (ADmax) and venular (VDmax) dilatation as well as the area under the arteriolar (AFarea) and venular (VFarea) flicker curve using a retinal vessel analyzer. Standardized assessments of CV risk factors, cardiorespiratory fitness, and retinal endothelial function were performed before and after HIIT. HIIT reduced body mass index, fat mass, and low-density lipoprotein and increased muscle mass and peak oxygen uptake (VO2peak). Both ADmax (pre: 2.7 ± 2.1\%, post: 3.0 ± 2.2\%, P = .018) and AFarea (pre: 32.6 ± 28.4\%*s, post: 37.7 ± 30.6\%*s, P = .016) increased after HIIT compared with CG (ADmax, pre: 3.2 ± 1.8\%, post: 2.9 ± 1.8\%, P = .254; AFarea, pre: 41.6 ± 28.5\%*s, post: 37.8 ± 27.0\%*s, P = .186). Venular function remained unchanged after HIIT. There was a significant association between ∆-change VO2peak and ∆-changes ADmax and AFarea (P = .026, R² = 0.073; P = .019, R² = 0.081, respectively). 12-weeks of HIIT improved retinal endothelial function in middle-aged patients with increased CV risk independent of the reduction in classical CV risk factors. Exercise has the potential to reverse or at least postpone progression of small vessel disease in older adults with increased CV risk under standard medication. Dynamic retinal vessel analysis seems to be a sensitive tool to detect treatment effects of exercise interventions on retinal microvascular endothelial function in middle-aged individuals with increased CV risk.}, language = {en} } @article{SchmidtTurgutLeetal.2020, author = {Schmidt, Aaron C. and Turgut, Hatice and Le, Dao and Beloqui, Ana and Delaittre, Guillaume}, title = {Making the best of it: nitroxide-mediated polymerization of methacrylates via the copolymerization approach with functional styrenics}, series = {Polymer Chemistry}, volume = {11}, journal = {Polymer Chemistry}, number = {2}, publisher = {Royal Society of Chemistry (RSC)}, address = {Cambridge}, doi = {10.1039/C9PY01458F}, pages = {593 -- 604}, year = {2020}, abstract = {The SG1-mediated solution polymerization of methyl methacrylate (MMA) and oligo(ethylene glycol) methacrylate (OEGMA, Mₙ = 300 g mol⁻¹) in the presence of a small amount of functional/reactive styrenic comonomer is investigated. Moieties such as pentafluorophenyl ester, triphenylphosphine, azide, pentafluorophenyl, halide, and pyridine are considered. A comonomer fraction as low as 5 mol\% typically results in a controlled/living behavior, at least up to 50\% conversion. Chain extensions with styrene for both systems were successfully performed. Variation of physical properties such as refractive index (for MMA) and phase transition temperature (for OEGMA) were evaluated by comparing to 100\% pure homopolymers. The introduction of an activated ester styrene derivative in the polymerization of OEGMA allows for the synthesis of reactive and hydrophilic polymer brushes with defined thickness. Finally, using the example of pentafluorostyrene as controlling comonomer, it is demonstrated that functional PMMA-b-PS are able to maintain a phase separation ability, as evidenced by the formation of nanostructured thin films.}, language = {en} } @article{HamouKotliarTanetal.2020, author = {Hamou, Hussam Aldin and Kotliar, Konstantin and Tan, Sonny Kian and Weiß, Christel and Blume, Christian and Clusmann, Hans and Schubert, Gerrit Alexander and Albanna, Walid}, title = {Surgical nuances and placement of subgaleal drains for supratentorial procedures—a prospective analysis of efficacy and outcome in 150 craniotomies}, series = {Acta Neurochirurgica}, volume = {2020}, journal = {Acta Neurochirurgica}, number = {162}, publisher = {Springer Nature}, address = {Cham}, issn = {0942-0940}, doi = {10.1007/s00701-019-04196-6}, pages = {729 -- 736}, year = {2020}, abstract = {Background For supratentorial craniotomy, surgical access, and closure technique, including placement of subgaleal drains, may vary considerably. The influence of surgical nuances on postoperative complications such as cerebrospinal fluid leakage or impaired wound healing overall remains largely unclear. With this study, we are reporting our experiences and the impact of our clinical routines on outcome in a prospectively collected data set. Method We prospectively observed 150 consecutive patients undergoing supratentorial craniotomy and recorded technical variables (type/length of incision, size of craniotomy, technique of dural and skin closure, type of dressing, and placement of subgaleal drains). Outcome variables (subgaleal hematoma/CSF collection, periorbital edema, impairment of wound healing, infection, and need for operative revision) were recorded at time of discharge and at late follow-up. Results Early subgaleal fluid collection was observed in 36.7\% (2.8\% at the late follow-up), and impaired wound healing was recorded in 3.3\% of all cases, with an overall need for operative revision of 6.7\%. Neither usage of dural sealants, lack of watertight dural closure, and presence of subgaleal drains, nor type of skin closure or dressing influenced outcome. Curved incisions, larger craniotomy, and tumor size, however, were associated with an increase in early CSF or hematoma collection (p < 0.0001, p = 0.001, p < 0.01 resp.), and larger craniotomy size was associated with longer persistence of subgaleal fluid collections (p < 0.05). Conclusions Based on our setting, individual surgical nuances such as the type of dural closure and the use of subgaleal drains resulted in a comparable complication rate and outcome. Subgaleal fluid collections were frequently observed after supratentorial procedures, irrespective of the closing technique employed, and resolve spontaneously in the majority of cases without significant sequelae. Our results are limited due to the observational nature in our single-center study and need to be validated by supportive prospective randomized design.}, language = {en} } @article{MennickenPeterKaulenetal.2020, author = {Mennicken, Max and Peter, Sophia K. and Kaulen, Corinna and Simon, Ulrich and Karth{\"a}user, Silvia}, title = {Transport through Redox-Active Ru-Terpyridine Complexes Integrated in Single Nanoparticle Devices}, series = {The Journal of Physical Chemistry C}, volume = {124}, journal = {The Journal of Physical Chemistry C}, number = {8}, publisher = {ACS Publications}, address = {Washington, DC}, issn = {1932-7455}, doi = {10.1021/acs.jpcc.9b11716}, pages = {4881 -- 4889}, year = {2020}, abstract = {Transition metal complexes are electrofunctional molecules due to their high conductivity and their intrinsic switching ability involving a metal-to-ligand charge transfer. Here, a method is presented to contact reliably a few to single redox-active Ru-terpyridine complexes in a CMOS compatible nanodevice and preserve their electrical functionality. Using hybrid materials from 14 nm gold nanoparticles (AuNP) and bis-{4′-[4-(mercaptophenyl)-2,2′:6′,2″-terpyridine]}-ruthenium(II) complexes a device size of 30² nm² inclusive nanoelectrodes is achieved. Moreover, this method bears the opportunity for further downscaling. The Ru-complex AuNP devices show symmetric and asymmetric current versus voltage curves with a hysteretic characteristic in two well separated conductance ranges. By theoretical approximations based on the single-channel Landauer model, the charge transport through the formed double-barrier tunnel junction is thoroughly analyzed and its sensibility to the molecule/metal contact is revealed. It can be verified that tunneling transport through the HOMO is the main transport mechanism while decoherent hopping transport is present to a minor extent.}, language = {en} } @article{CapitainRossJonesMoehringetal.2020, author = {Capitain, Charlotte and Ross-Jones, Jesse and M{\"o}hring, Sophie and Tippk{\"o}tter, Nils}, title = {Differential scanning calorimetry for quantification of polymer biodegradability in compost}, series = {International Biodeterioration \& Biodegradation}, volume = {149}, journal = {International Biodeterioration \& Biodegradation}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0964-8305}, doi = {10.1016/j.ibiod.2020.104914}, pages = {In Press, Article number 104914}, year = {2020}, abstract = {The objective of this study is the establishment of a differential scanning calorimetry (DSC) based method for online analysis of the biodegradation of polymers in complex environments. Structural changes during biodegradation, such as an increase in brittleness or crystallinity, can be detected by carefully observing characteristic changes in DSC profiles. Until now, DSC profiles have not been used to draw quantitative conclusions about biodegradation. A new method is presented for quantifying the biodegradation using DSC data, whereby the results were validated using two reference methods. The proposed method is applied to evaluate the biodegradation of three polymeric biomaterials: polyhydroxybutyrate (PHB), cellulose acetate (CA) and Organosolv lignin. The method is suitable for the precise quantification of the biodegradability of PHB. For CA and lignin, conclusions regarding their biodegradation can be drawn with lower resolutions. The proposed method is also able to quantify the biodegradation of blends or composite materials, which differentiates it from commonly used degradation detection methods.}, language = {en} } @article{JildehKirchnerOberlaenderetal.2020, author = {Jildeh, Zaid B. and Kirchner, Patrick and Oberl{\"a}nder, Jan and Vahidpour, Farnoosh and Wagner, Patrick H. and Sch{\"o}ning, Michael Josef}, title = {Development of a package-sterilization process for aseptic filling machines: A numerical approach and validation for surface treatment with hydrogen peroxide}, series = {Sensor and Actuators A: Physical}, volume = {303}, journal = {Sensor and Actuators A: Physical}, number = {111691}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0924-4247}, doi = {10.1016/j.sna.2019.111691}, year = {2020}, abstract = {Within the present work a sterilization process by a heated gas mixture that contains hydrogen peroxide (H₂O₂) is validated by experiments and numerical modeling techniques. The operational parameters that affect the sterilization efficacy are described alongside the two modes of sterilization: gaseous and condensed H₂O₂. Measurements with a previously developed H₂O₂ gas sensor are carried out to validate the applied H₂O₂ gas concentration during sterilization. We performed microbiological tests at different H₂O₂ gas concentrations by applying an end-point method to carrier strips, which contain different inoculation loads of Geobacillus stearothermophilus spores. The analysis of the sterilization process of a pharmaceutical glass vial is performed by numerical modeling. The numerical model combines heat- and advection-diffusion mass transfer with vapor-pressure equations to predict the location of condensate formation and the concentration of H₂O₂ at the packaging surfaces by changing the gas temperature. For a sterilization process of 0.7 s, a H₂O₂ gas concentration above 4\% v/v is required to reach a log-count reduction above six. The numerical results showed the location of H₂O₂ condensate formation, which decreases with increasing sterilant-gas temperature. The model can be transferred to different gas nozzle- and packaging geometries to assure the absence of H₂O₂ residues.}, language = {en} } @inproceedings{KreyerMuellerEsch2020, author = {Kreyer, J{\"o}rg and M{\"u}ller, Marvin and Esch, Thomas}, title = {A Map-Based Model for the Determination of Fuel Consumption for Internal Combustion Engines as a Function of Flight Altitude}, series = {Deutscher Luft- und Raumfahrtkongress 2019, „Luft- und Raumfahrt - technologische Br{\"u}cke in die Zukunft", Darmstadt, 30. September bis 2. Oktober 2019}, booktitle = {Deutscher Luft- und Raumfahrtkongress 2019, „Luft- und Raumfahrt - technologische Br{\"u}cke in die Zukunft", Darmstadt, 30. September bis 2. Oktober 2019}, publisher = {Deutsche Gesellschaft f{\"u}r Luft- und Raumfahrt - Lilienthal-Oberth e.V}, address = {Bonn}, doi = {10.25967/490162}, pages = {13 Seiten}, year = {2020}, language = {en} } @inproceedings{FingerBraunBil2020, author = {Finger, Felix and Braun, Carsten and Bil, Cees}, title = {Comparative assessment of parallel-hybrid-electric propulsion systems for four different aircraft}, series = {AIAA SciTech Forum 2020, 06.01.2020 - 10.01.2020, Orlando}, booktitle = {AIAA SciTech Forum 2020, 06.01.2020 - 10.01.2020, Orlando}, doi = {10.2514/6.2020-1502}, pages = {15 Seiten}, year = {2020}, language = {en} } @article{RauschKahmannBaltschunetal.2020, author = {Rausch, Valentin and Kahmann, Stephanie Lucina and Baltschun, Christoph and Staat, Manfred and M{\"u}ller, Lars P. and Wegmann, Kilian}, title = {Pressure distribution to the distal biceps tendon at the radial tuberosity: a biomechanical study}, series = {The Journal of Hand Surgery}, volume = {45}, journal = {The Journal of Hand Surgery}, number = {8}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0363-5023}, doi = {10.1016/j.jhsa.2020.01.006}, pages = {776.e1 -- 776.e9}, year = {2020}, abstract = {Purpose Mechanical impingement at the narrow radioulnar space of the tuberosity is believed to be an etiological factor in the injury of the distal biceps tendon. The aim of the study was to compare the pressure distribution at the proximal radioulnar space between 2 fixation techniques and the intact state. Methods Six right arms and 6 left arms from 5 female and 6 male frozen specimens were used for this study. A pressure transducer was introduced at the height of the radial tuberosity with the intact distal biceps tendon and after 2 fixation methods: the suture-anchor and the cortical button technique. The force (N), maximum pressure (kPa) applied to the radial tuberosity, and the contact area (mm²) of the radial tuberosity with the ulna were measured and differences from the intact tendon were detected from 60° supination to 60° pronation in 15° increments with the elbow in full extension and in 45° and 90° flexion of the elbow. Results With the distal biceps tendon intact, the pressures during pronation were similar regardless of extension and flexion and were the highest at 60° pronation with 90° elbow flexion (23.3 ± 53.5 kPa). After repair of the tendon, the mean peak pressure, contact area, and total force showed an increase regardless of the fixation technique. Highest peak pressures were found using the cortical button technique at 45° flexion of the elbow and 60° pronation. These differences were significantly different from the intact tendon. The contact area was significantly larger in full extension and 15°, 30°, and 60° pronation using the cortical button technique. Conclusions Pressures on the distal biceps tendon at the radial tuberosity increase during pronation, especially after repair of the tendon. Clinical relevance Mechanical impingement could play a role in both the etiology of primary distal biceps tendon ruptures and the complications occurring after fixation of the tendon using certain techniques.}, language = {en} } @article{DigelKernGeenenetal.2020, author = {Digel, Ilya and Kern, Inna and Geenen, Eva-Maria and Akimbekov, Nuraly}, title = {Dental plaque removal by ultrasonic toothbrushes}, series = {dentistry journal}, volume = {8}, journal = {dentistry journal}, number = {28}, publisher = {MDPI}, address = {Basel}, issn = {2304-6767}, doi = {10.3390/dj8010028}, pages = {1 -- 13}, year = {2020}, abstract = {With the variety of toothbrushes on the market, the question arises, which toothbrush is best suited to maintain oral health? This thematic review focuses first on plaque formation mechanisms and then on the plaque removal effectiveness of ultrasonic toothbrushes and their potential in preventing oral diseases like periodontitis, gingivitis, and caries. We overviewed the physical effects that occurred during brushing and tried to address the question of whether ultrasonic toothbrushes effectively reduced the microbial burden by increasing the hydrodynamic forces. The results of published studies show that electric toothbrushes, which combine ultrasonic and sonic (or acoustic and mechanic) actions, may have the most promising effect on good oral health. Existing ultrasonic/sonic toothbrush models do not significantly differ regarding the removal of dental biofilm and the reduction of gingival inflammation compared with other electrically powered toothbrushes, whereas the manual toothbrushes show a lower effectiveness.}, language = {en} } @article{WilbringEnningPfaffetal.2020, author = {Wilbring, Daniela and Enning, Manfred and Pfaff, Raphael and Schmidt, Bernd}, title = {Neue Perspektiven f{\"u}r die Bahn in der Produktions- und Distributionslogistik durch Prozessautomation}, series = {ETR - Eisenbahntechnische Rundschau}, volume = {69}, journal = {ETR - Eisenbahntechnische Rundschau}, number = {3}, issn = {0013-2845}, pages = {15 -- 19}, year = {2020}, language = {de} } @inproceedings{DinghoferHartung2020, author = {Dinghofer, Kai and Hartung, Frank}, title = {Analysis of Criteria for the Selection of Machine Learning Frameworks}, series = {2020 International Conference on Computing, Networking and Communications (ICNC)}, booktitle = {2020 International Conference on Computing, Networking and Communications (ICNC)}, doi = {10.1109/ICNC47757.2020.9049650}, pages = {373 -- 377}, year = {2020}, language = {en} } @article{MuschallikMolinnusJablonskietal.2020, author = {Muschallik, Lukas and Molinnus, Denise and Jablonski, Melanie and Kipp, Carina Ronja and Bongaerts, Johannes and Pohl, Martina and Wagner, Torsten and Sch{\"o}ning, Michael Josef and Selmer, Thorsten and Siegert, Petra}, title = {Synthesis of α-hydroxy ketones and vicinal (R, R)-diols by Bacillus clausii DSM 8716ᵀ butanediol dehydrogenase}, series = {RSC Advances}, volume = {10}, journal = {RSC Advances}, publisher = {Royal Society of Chemistry (RSC)}, address = {Cambridge}, issn = {2046-2069}, doi = {10.1039/D0RA02066D}, pages = {12206 -- 12216}, year = {2020}, abstract = {α-hydroxy ketones (HK) and 1,2-diols are important building blocks for fine chemical synthesis. Here, we describe the R-selective 2,3-butanediol dehydrogenase from B. clausii DSM 8716ᵀ (BcBDH) that belongs to the metal-dependent medium chain dehydrogenases/reductases family (MDR) and catalyzes the selective asymmetric reduction of prochiral 1,2-diketones to the corresponding HK and, in some cases, the reduction of the same to the corresponding 1,2-diols. Aliphatic diketones, like 2,3-pentanedione, 2,3-hexanedione, 5-methyl-2,3-hexanedione, 3,4-hexanedione and 2,3-heptanedione are well transformed. In addition, surprisingly alkyl phenyl dicarbonyls, like 2-hydroxy-1-phenylpropan-1-one and phenylglyoxal are accepted, whereas their derivatives with two phenyl groups are not substrates. Supplementation of Mn²⁺ (1 mM) increases BcBDH's activity in biotransformations. Furthermore, the biocatalytic reduction of 5-methyl-2,3-hexanedione to mainly 5-methyl-3-hydroxy-2-hexanone with only small amounts of 5-methyl-2-hydroxy-3-hexanone within an enzyme membrane reactor is demonstrated.}, language = {en} }