@article{PourshahidiAchtsnichtNambipareecheeetal.2021, author = {Pourshahidi, Ali Mohammad and Achtsnicht, Stefan and Nambipareechee, Mrinal Murali and Offenh{\"a}usser, Andreas and Krause, Hans-Joachim}, title = {Multiplex detection of magnetic beads using offset field dependent frequency mixing magnetic detection}, series = {Sensors}, volume = {21}, journal = {Sensors}, number = {17}, publisher = {MDPI}, address = {Basel}, issn = {1424-8220}, doi = {10.3390/s21175859}, pages = {16 Seiten}, year = {2021}, abstract = {Magnetic immunoassays employing Frequency Mixing Magnetic Detection (FMMD) have recently become increasingly popular for quantitative detection of various analytes. Simultaneous analysis of a sample for two or more targets is desirable in order to reduce the sample amount, save consumables, and save time. We show that different types of magnetic beads can be distinguished according to their frequency mixing response to a two-frequency magnetic excitation at different static magnetic offset fields. We recorded the offset field dependent FMMD response of two different particle types at frequencies ƒ₁ + n⋅ƒ₂, n = 1, 2, 3, 4 with ƒ₁ = 30.8 kHz and ƒ₂ = 63 Hz. Their signals were clearly distinguishable by the locations of the extremes and zeros of their responses. Binary mixtures of the two particle types were prepared with different mixing ratios. The mixture samples were analyzed by determining the best linear combination of the two pure constituents that best resembled the measured signals of the mixtures. Using a quadratic programming algorithm, the mixing ratios could be determined with an accuracy of greater than 14\%. If each particle type is functionalized with a different antibody, multiplex detection of two different analytes becomes feasible.}, language = {en} } @article{Gaigall2021, author = {Gaigall, Daniel}, title = {Test for Changes in the Modeled Solvency Capital Requirement of an Internal Risk Model}, series = {ASTIN Bulletin}, volume = {51}, journal = {ASTIN Bulletin}, number = {3}, publisher = {Cambridge Univ. Press}, address = {Cambridge}, issn = {1783-1350}, doi = {10.1017/asb.2021.20}, pages = {813 -- 837}, year = {2021}, abstract = {In the context of the Solvency II directive, the operation of an internal risk model is a possible way for risk assessment and for the determination of the solvency capital requirement of an insurance company in the European Union. A Monte Carlo procedure is customary to generate a model output. To be compliant with the directive, validation of the internal risk model is conducted on the basis of the model output. For this purpose, we suggest a new test for checking whether there is a significant change in the modeled solvency capital requirement. Asymptotic properties of the test statistic are investigated and a bootstrap approximation is justified. A simulation study investigates the performance of the test in the finite sample case and confirms the theoretical results. The internal risk model and the application of the test is illustrated in a simplified example. The method has more general usage for inference of a broad class of law-invariant and coherent risk measures on the basis of a paired sample.}, language = {en} } @inproceedings{KohlbergerWildKasperetal.2021, author = {Kohlberger, David-Sharif and Wild, Dominik and Kasper, Stefan and Czupalla, Markus}, title = {Modeling and analyses of a thermal passively stabilized LEO/GEO star tracker with embedded phase change material applying the Infused Thermal Solutions (ITS) method}, series = {ICES202: Satellite, Payload, and Instrument Thermal Control}, booktitle = {ICES202: Satellite, Payload, and Instrument Thermal Control}, publisher = {Texas Tech University}, address = {Lubbock, Tex.}, pages = {12 Seiten}, year = {2021}, abstract = {Phase change materials offer a way of storing excess heat and releasing it when it is needed. They can be utilized as a method to control thermal behavior without the need for additional energy. This work focuses on exploring the potential of using phase change materials to passively control the thermal behavior of a star tracker by infusing it with a fitting phase change material. Based on the numerical model of the star trackers thermal behavior using ESATAN-TMS without implemented phase change material, a fitting phase change material for selected orbits is chosen and implemented in the thermal model. The altered thermal behavior of the numerical model after the implementation is analyzed for different amounts of the chosen phase change materials using an ESATAN-based subroutine developed by the FH Aachen. The PCM-modelling-subroutine is explained in the paper ICES-2021-110. The results show that an increasing amount of phase change material increasingly damps temperature oscillations. Using an integral part structure some of the mass increase can be compensated.}, language = {en} }