Dokument-ID Dokumenttyp Verfasser/Autoren Herausgeber Haupttitel Abstract Auflage Verlagsort Verlag Erscheinungsjahr Seitenzahl Schriftenreihe Titel Schriftenreihe Bandzahl ISBN Quelle der Hochschulschrift Konferenzname Bemerkung Quelle:Titel Quelle:Jahrgang Quelle:Heftnummer Quelle:Erste Seite Quelle:Letzte Seite URN DOI Zugriffsart Link Abteilungen OPUS4-4812 Wissenschaftlicher Artikel Nguyen, Nhu Huynh, ; Duong, Minh Tuan, duong@fh-aachen.de; Tran, Thanh Ngoc, tran@fh-aachen.de; Pham, Phu Tinh, ; Grottke, O., ; Tolba, R., ; Staat, Manfred, m.staat@fh-aachen.de Influence of a freeze-thaw cycle on the stress-stretch curves of tissues of porcine abdominal organs The paper investigates both fresh porcine spleen and liver and the possible decomposition of these organs under a freeze-thaw cycle. The effect of tissue preservation condition is an important factor which should be taken into account for protracted biomechanical tests. In this work, tension tests were conducted for a large number of tissue specimens from twenty pigs divided into two groups of 10. Concretely, the first group was tested in fresh state; the other one was tested after a freeze-thaw cycle which simulates the conservation conditions before biomechanical experiments. A modified Fung model for isotropic behavior was adopted for the curve fitting of each kind of tissues. Experimental results show strong effects of the realistic freeze-thaw cycle on the capsule of elastin-rich spleen but negligible effects on the liver which virtually contains no elastin. This different behavior could be explained by the autolysis of elastin by elastolytic enzymes during the warmer period after thawing. Realistic biomechanical properties of elastin-rich organs can only be expected if really fresh tissue is tested. The observations are supported by tests of intestines. Amsterdam Elsevier 2012 4 Journal of Biomechanics 45 14 2382 2386 10.1016/j.jbiomech.2012.07.008 campus https://doi.org/10.1016/j.jbiomech.2012.07.008 Fachbereich Medizintechnik und Technomathematik