Dokument-ID Dokumenttyp Verfasser/Autoren Herausgeber Haupttitel Abstract Auflage Verlagsort Verlag Erscheinungsjahr Seitenzahl Schriftenreihe Titel Schriftenreihe Bandzahl ISBN Quelle der Hochschulschrift Konferenzname Bemerkung Quelle:Titel Quelle:Jahrgang Quelle:Heftnummer Quelle:Erste Seite Quelle:Letzte Seite URN DOI Zugriffsart Link Abteilungen OPUS4-7089 Wissenschaftlicher Artikel Pilas, Johanna, pilas@fh-aachen.de; Iken, Heiko, iken@fh-aachen.de; Selmer, Thorsten, selmer@fh-aachen.de; Keusgen, Michael, ; Schöning, Michael Josef, schoening@fh-aachen.de Development of a multi-parameter sensor chip for the simultaneous detection of organic compounds in biogas processes Weinheim Wiley 2015 6 Physica status solidi (a) 212 6 1306 1312 10.1002/pssa.201431894 Fachbereich Chemie und Biotechnologie OPUS4-7336 Wissenschaftlicher Artikel Pilas, Johanna, pilas@fh-aachen.de; Mariano, K., ; Keusgen, M., ; Selmer, Thorsten, selmer@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de Optimization of an Enzyme-based Multi-parameter Biosensor for Monitoring Biogas Processes Amsterdam Elsevier 2015 3 Procedia Engineering 120 Eurosensors 2015 532 535 10.1016/j.proeng.2015.08.702 Fachbereich Chemie und Biotechnologie OPUS4-8157 Wissenschaftlicher Artikel Röhlen, Desiree, roehlen@fh-aachen.de; Pilas, Johanna, pilas@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de; Selmer, Thorsten, selmer@fh-aachen.de Development of an Amperometric Biosensor Platform for the Combined Determination of l-Malic, Fumaric, and l-Aspartic Acid Berlin Springer 2017 15 Applied Biochemistry and Biotechnology 1 16 10.1007/s12010-017-2578-1 Fachbereich Chemie und Biotechnologie OPUS4-8158 Wissenschaftlicher Artikel Pilas, Johanna, pilas@fh-aachen.de; Yazici, Yasemen, ; Selmer, Thorsten, selmer@fh-aachen.de; Keusgen, Michael, ; Schöning, Michael Josef, schoening@fh-aachen.de Optimization of an amperometric biosensor array for simultaneous measurement of ethanol, formate, d- and l-lactate Amsterdam Elsevier 2017 6 Electrochimica Acta 251 256 262 10.1016/j.electacta.2017.07.119 Fachbereich Chemie und Biotechnologie OPUS4-8421 Wissenschaftlicher Artikel Pilas, Johanna, pilas@fh-aachen.de; Yazici, Y., ; Selmer, Thorsten, selmer@fh-aachen.de; Keusgen, M., ; Schöning, Michael Josef, schoening@fh-aachen.de Application of a portable multi-analyte biosensor for organic acid determination in silage Multi-analyte biosensors may offer the opportunity to perform cost-effective and rapid analysis with reduced sample volume, as compared to electrochemical biosensing of each analyte individually. This work describes the development of an enzyme-based biosensor system for multi-parametric determination of four different organic acids. The biosensor array comprises five working electrodes for simultaneous sensing of ethanol, formate, d-lactate, and l-lactate, and an integrated counter electrode. Storage stability of the biosensor was evaluated under different conditions (stored at +4 °C in buffer solution and dry at −21 °C, +4 °C, and room temperature) over a period of 140 days. After repeated and regular application, the individual sensing electrodes exhibited the best stability when stored at −21 °C. Furthermore, measurements in silage samples (maize and sugarcane silage) were conducted with the portable biosensor system. Comparison with a conventional photometric technique demonstrated successful employment for rapid monitoring of complex media. Basel MDPI 2018 12 Seiten Sensors 18 Article number 1470 5 10.3390/s18051470 weltweit https://doi.org/10.3390/s18051470 Fachbereich Chemie und Biotechnologie OPUS4-8603 Wissenschaftlicher Artikel Röhlen, Desiree, roehlen@fh-aachen.de; Pilas, Johanna, pilas@fh-aachen.de; Dahmen, Markus, dahmen@fh-aachen.de; Keusgen, Michael, ; Selmer, Thorsten, selmer@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de Toward a Hybrid Biosensor System for Analysis of Organic and Volatile Fatty Acids in Fermentation Processes Monitoring of organic acids (OA) and volatile fatty acids (VFA) is crucial for the control of anaerobic digestion. In case of unstable process conditions, an accumulation of these intermediates occurs. In the present work, two different enzyme-based biosensor arrays are combined and presented for facile electrochemical determination of several process-relevant analytes. Each biosensor utilizes a platinum sensor chip (14 × 14 mm²) with five individual working electrodes. The OA biosensor enables simultaneous measurement of ethanol, formate, d- and l-lactate, based on a bi-enzymatic detection principle. The second VFA biosensor provides an amperometric platform for quantification of acetate and propionate, mediated by oxidation of hydrogen peroxide. The cross-sensitivity of both biosensors toward potential interferents, typically present in fermentation samples, was investigated. The potential for practical application in complex media was successfully demonstrated in spiked sludge samples collected from three different biogas plants. Thereby, the results obtained by both of the biosensors were in good agreement to the applied reference measurements by photometry and gas chromatography, respectively. The proposed hybrid biosensor system was also used for long-term monitoring of a lab-scale biogas reactor (0.01 m³) for a period of 2 months. In combination with typically monitored parameters, such as gas quality, pH and FOS/TAC (volatile organic acids/total anorganic carbonate), the amperometric measurements of OA and VFA concentration could enhance the understanding of ongoing fermentation processes. Lausanne Frontiers 2018 10 Frontiers in Chemistry 6 Article 284 1 11 10.3389/fchem.2018.00284 weltweit http://doi.org/10.3389/fchem.2018.00284 Fachbereich Chemie und Biotechnologie OPUS4-8859 Wissenschaftlicher Artikel Breuer, Lars, L.Breuer@fh-aachen.de; Pilas, Johanna, pilas@fh-aachen.de; Guthmann, Eric, ; Schöning, Michael Josef, schoening@fh-aachen.de; Thoelen, Ronald, ; Wagner, Torsten, torsten.wagner@fh-aachen.de Towards light-addressable flow control: responsive hydrogels with incorporated graphene oxide as laser-driven actuator structures within microfluidic channels Amsterdam Elsevier 2019 6 Sensor and Actuators B: Chemical 288 579 585 10.1016/j.snb.2019.02.086 bezahl https://doi.org/10.1016/j.snb.2019.02.086 Fachbereich Medizintechnik und Technomathematik OPUS4-9213 Wissenschaftlicher Artikel Pilas, Johanna, pilas@fh-aachen.de; Selmer, Thorsten, selmer@fh-aachen.de; Keusgen, Michael, ; Schöning, Michael Josef, schoening@fh-aachen.de Screen-printed carbon electrodes modified with graphene oxide for the design of a reagent-free NAD+-dependent biosensor array 2019 6 Analytical Chemistry 91 23 15293 15299 10.1021/acs.analchem.9b04481 campus https://doi.org/10.1021/acs.analchem.9b04481 Fachbereich Medizintechnik und Technomathematik