Dokument-ID Dokumenttyp Verfasser/Autoren Herausgeber Haupttitel Abstract Auflage Verlagsort Verlag Erscheinungsjahr Seitenzahl Schriftenreihe Titel Schriftenreihe Bandzahl ISBN Quelle der Hochschulschrift Konferenzname Bemerkung Quelle:Titel Quelle:Jahrgang Quelle:Heftnummer Quelle:Erste Seite Quelle:Letzte Seite URN DOI Zugriffsart Link Abteilungen OPUS4-4851 Wissenschaftlicher Artikel Schusser, Sebastian, schusser@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de; Bäcker, Matthias, baecker@fh-aachen.de; Leinhos, Marcel, leinhos@fh-aachen.de; Wagner, Patrick, ; Schöning, Michael Josef, schoening@fh-aachen.de Characterization of biodegradable polymers with capacitive field-effect sensors In vitro studies of the degradation kinetic of biopolymers are essential for the design and optimization of implantable biomedical devices. In the presented work, a field-effect capacitive sensor has been applied for the real-time and in situ monitoring of degradation processes of biopolymers for the first time. The polymer-covered field-effect sensor is, in principle, capable to detect any changes in bulk, surface and interface properties of the polymer induced by degradation processes. The feasibility of this approach has been experimentally proven by using the commercially available biomedical polymer poly(D,L-lactic acid) (PDLLA) as a model system. PDLLA films of different thicknesses were deposited on the Ta₂O₅-gate surface of the field-effect structure from a polymer solution by means of spin-coating method. The polymer-modified field-effect sensors have been characterized by means of capacitance-voltage and impedance-spectroscopy method. The degradation of the PDLLA was accelerated by changing the degradation medium from neutral (pH 7.2) to alkaline (pH 9) condition, resulting in drastic changes in the capacitance and impedance spectra of the polymer-modified field-effect sensor. Amsterdam Elsevier 2012 5 Sensors and actuators B: Chemical 187 Part of special issue "Selected Papers from the 14th International Meeting on Chemical Sensors" 2 7 10.1016/j.snb.2012.07.099 campus https://doi.org/10.1016/j.snb.2012.07.099 Fachbereich Medizintechnik und Technomathematik OPUS4-6690 Wissenschaftlicher Artikel Schusser, Sebastian, schusser@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de; Bäcker, Matthias, baecker@fh-aachen.de; Krischer, M., ; Leinhos, Marcel, leinhos@fh-aachen.de; Wagner, P., ; Schöning, Michael Josef, schoening@fh-aachen.de An application of field-effect sensors for in-situ monitoring of degradation of biopolymers Amsterdam Elsevier 2015 5 Sensors and actuators B: Chemical 207 Part B 954 959 campus http://dx.doi.org/10.1016/j.snb.2014.10.058 Fachbereich Medizintechnik und Technomathematik OPUS4-5680 Wissenschaftlicher Artikel Schusser, Sebastian, schusser@fh-aachen.de; Menzel, S., ; Bäcker, Matthias, baecker@fh-aachen.de; Leinhos, Marcel, leinhos@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de; Wagner, P., ; Schöning, Michael Josef, schoening@fh-aachen.de Degradation of thin poly(lactic acid) films: characterization by capacitance-voltage, atomic force microscopy, scanning electron microscopy and contact-angle measurements Amsterdam Elsevier 2013 5 Electrochimica Acta Vol. 113 779 784 campus http://dx.doi.org/10.1016/j.electacta.2013.08.025 Fachbereich Medizintechnik und Technomathematik OPUS4-4677 Wissenschaftlicher Artikel Schusser, Sebastian, schusser@fh-aachen.de; Leinhos, Marcel, leinhos@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de; Wagner, Patrick, ; Schöning, Michael Josef, schoening@fh-aachen.de Biopolymer-degradation monitoring by chip-­based impedance spectroscopy technique - 2012 0 Nanoscale Science and Technology (NS&T´12) : Proceedings Book Humboldt Kolleg <2012, Tunisia> ; Tunisia, 17-19 March, 2012 / ed. by Michael J. Schöning ; Adnane Abdelghani Proceedings of the 2nd Humboldt Kolleg, Hammamet, Tunisia, 17-19 March, 2012 Organizer: Alexander von Humboldt Stiftung, Germany. pdf 184 p. 47 47 weltweit http://opus.bibliothek.fh-aachen.de/opus/volltexte/2012/354/ Fachbereich Medizintechnik und Technomathematik OPUS4-5317 Wissenschaftlicher Artikel Schusser, Sebastian, schusser@fh-aachen.de; Leinhos, Marcel, leinhos@fh-aachen.de; Bäcker, Matthias, baecker@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de; Wagner, Patrick, ; Schöning, Michael Josef, schoening@fh-aachen.de Impedance spectroscopy: A tool for real-time in situ monitoring of the degradation of biopolymers Weinheim Wiley 2013 5 Physica Status Solidi (A). Vol. 210 (2013), iss. 5 905 910 campus http://onlinelibrary.wiley.com/doi/10.1002/pssa.201200941/pdf Fachbereich Medizintechnik und Technomathematik OPUS4-6112 Konferenzveröffentlichung Schusser, Sebastian, schusser@fh-aachen.de; Bäcker, Matthias, baecker@fh-aachen.de; Leinhos, Marcel, leinhos@fh-aachen.de; Krischer, M., ; Wenzel, L., ; Poghossian, Arshak, poghossian@fh-aachen.de; Wagner, Patrick, ; Schöning, Michael Josef, schoening@fh-aachen.de Sensorkonzept zur in vitro Echtzeitmessung des Degradationsverhaltens von biodegradierbaren Biopolymeren 2013 3 11. Dresdner Sensor-Symposium : 9.-11.12.2013 978-3-9813484-5-3 174 177 weltweit http://dx.doi.org/10.5162/11dss2013/A11 Fachbereich Medizintechnik und Technomathematik OPUS4-6816 Wissenschaftlicher Artikel Schusser, Sebastian, schusser@fh-aachen.de; Bäcker, Matthias, baecker@fh-aachen.de; Krischer, M., ; Wenzel, L., ; Leinhos, Marcel, leinhos@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de; Biselli, Manfred, biselli@fh-aachen.de; Wagner, P., ; Schöning, Michael Josef, schoening@fh-aachen.de Enzymatically catalyzed degradation of biodegradable polymers investigated by means of a semiconductor-based field-effect sensor A semiconductor field-effect device has been used for an enzymatically catalyzed degradation of biopolymers for the first time. This novel technique is capable to monitor the degradation process of multiple samples in situ and in real-time. As model system, the degradation of the biopolymer poly(D, L-lactic acid) has been monitored in the degradation medium containing the enzyme lipase from Rhizomucor miehei. The obtained results demonstrate the potential of capacitive field-effect sensors for degradation studies of biodegradable polymers. Amsterdam Elsevier 2014 3 Procedia Engineering 87 EUROSENSORS 2014 ; European Conference on Solid-State Transducers <28, 2014> 1314 1317 10.1016/j.proeng.2014.11.689 weltweit https://doi.org/10.1016/j.proeng.2014.11.689 Fachbereich Medizintechnik und Technomathematik OPUS4-7594 Teil eines Buches Poghossian, Arshak, poghossian@fh-aachen.de; Schusser, Sebastian, schusser@fh-aachen.de; Bäcker, M., ; Leinhos, Marcel, leinhos@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de Real-time in-situ electrical monitoring of the degradation of biopolymers using semiconductor field-effect devices Hauppauge Nova Science Publ. 2015 18 Biodegradable biopolymers. Vol. 1 978-1-63483-632-6 135 153 Fachbereich Medizintechnik und Technomathematik OPUS4-6390 Wissenschaftlicher Artikel Leinhos, Marcel, leinhos@fh-aachen.de; Schusser, Sebastian, schusser@fh-aachen.de; Bäcker, Matthias, baecker@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de Micromachined multi-parameter sensor chip for the control of polymer-degradation medium It is well known that the degradation environment can strongly influence the biodegradability and kinetics of biodegradation processes of polymers. Therefore, besides the monitoring of the degradation process, it is also necessary to control the medium in which the degradation takes place. In this work, a micromachined multi-parameter sensor chip for the control of the polymer-degradation medium has been developed. The chip combines a capacitive field-effect pH sensor, a four-electrode electrolyte-conductivity sensor and a thin-film Pt-temperature sensor. The results of characterization of individual sensors are presented. In addition, the multi-parameter sensor chip together with an impedimetric polymer-degradation sensor was simultaneously characterized in degradation solutions with different pH and electrolyte conductivity. The obtained results demonstrate the feasibility of the multi-parameter sensor chip for the control of the polymer-degradation medium. Weinheim Wiley-VCH 2014 5 Physica Status Solidi (A) : special issue on engineering and functional interfaces 211 6 1346 1351 10.1002/pssa.201330364 campus https://doi.org/10.1002/pssa.201330364 Fachbereich Medizintechnik und Technomathematik OPUS4-6727 Konferenzveröffentlichung Bäcker, Matthias, baecker@fh-aachen.de; Schusser, Sebastian, schusser@fh-aachen.de; Leinhos, Marcel, leinhos@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de Sensor system for the monitoring of degradation processes of biodegradable biopolymers Düsseldorf VDE-Verl. 2014 1 CD-ROM Sensoren und Messsysteme 2014 ; Beiträge der 17. GMA/ITG-Fachtagung vom 3. bis 4. Juni 2014 in Nürnberg. (ITG-Fachbericht ; 250) 978-3-8007-3622-5 1 4 Fachbereich Medizintechnik und Technomathematik