Dokument-ID Dokumenttyp Verfasser/Autoren Herausgeber Haupttitel Abstract Auflage Verlagsort Verlag Erscheinungsjahr Seitenzahl Schriftenreihe Titel Schriftenreihe Bandzahl ISBN Quelle der Hochschulschrift Konferenzname Bemerkung Quelle:Titel Quelle:Jahrgang Quelle:Heftnummer Quelle:Erste Seite Quelle:Letzte Seite URN DOI Zugriffsart Link Abteilungen OPUS4-4363 Wissenschaftlicher Artikel Werner, Frederik, f.werner@fh-aachen.de; Krumbe, Christoph, ; Schumacher, Katharina, ; Groebel, Simone, groebel@fh-aachen.de; Spelthahn, Heiko, spelthahn@fh-aachen.de; Stellberg, Michael, stellberg@fh-aachen.de; Wagner, Torsten, torsten.wagner@fh-aachen.de; Yoshinobu, Tatsuo, ; Selmer, Thorsten, selmer@fh-aachen.de; Keusgen, Michael, ; Baumann, Marcus, rektor@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de Determination of the extracellular acidification of Escherichia coli by a light-addressable potentiometric sensor Weinheim Wiley 2011 4 Physica status solidi (a) : applications and material science. 208 (2011), H. 6 1862-6319 1340 1344 campus http://dx.doi.org/10.1002/pssa.201001141 Fachbereich Chemie und Biotechnologie OPUS4-3446 Wissenschaftlicher Artikel Wagner, Torsten, torsten.wagner@fh-aachen.de; Maris, Rob J., ; Ackermann, Hans-Josef, h-j.ackermann@fh-aachen.de; Otto, Ralph, ; Beging, Stefan, beging@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de Handheld measurement device for field-effect sensor structures: Practical evaluation and limitations 2007 6 Sensors and Actuators B: Chemical . 127 (2007), H. 1 0925-4005 217 223 campus http://dx.doi.org/10.1016/j.snb.2007.07.073 Fachbereich Medizintechnik und Technomathematik OPUS4-4218 Wissenschaftlicher Artikel Wagner, Torsten, torsten.wagner@fh-aachen.de; Werner, Frederik, f.werner@fh-aachen.de; Miyamoto, Ko-ichiro, ; Ackermann, Hans-Josef, h-j.ackermann@fh-aachen.de; Yoshinobu, Tatsuo, ; Schöning, Michael Josef, schoening@fh-aachen.de FPGA-based LAPS device for the flexible design of sensing sites on functional interfaces 2010 5 Physica Status Solidi (A). 207 (2010), H. 4 1862-6300 Special Issue: Engineering of Functional Interfaces EnFI 2009 844 849 campus http://dx.doi.org/10.1002/pssa.200983320 Fachbereich Medizintechnik und Technomathematik OPUS4-1766 Wissenschaftlicher Artikel Thust, Marion, ; Mulchandani, Ashok, ; Wang, Joseph, ; Arzdorf, Michael, ; Mulchandani, Priti, ; Chen, Wilfried, ; Schöning, Michael Josef, schoening@fh-aachen.de Feldeffekt-Enzymsensor zur Detektion von Pestiziden 2003 3 Technisches Messen. 70 (2003), H. 12 0171-8096 561 564 bezahl http://dx.doi.org/10.1524/teme.70.12.561.20265 Fachbereich Medizintechnik und Technomathematik OPUS4-1767 Wissenschaftlicher Artikel Keusgen, Michael, ; Jünger, Martina, ; Krest, Ingo, ; Schöning, Michael Josef, schoening@fh-aachen.de Biosensoric detection of the cysteine sulphoxide alliin 2003 5 Sensors and Actuators B. 95 (2003), H. 1-3 0925-4005 297 302 campus http://dx.doi.org/10.1016/S0925-4005(03)00427-1 Fachbereich Medizintechnik und Technomathematik OPUS4-3244 Wissenschaftlicher Artikel Turek, Monika, ; Ketterer, Lothar, ; Claßen, Melanie, melanie.classen@fh-aachen.de; Berndt, Heinz, h.berndt@fh-aachen.de; Elbers, Gereon, elbers@fh-aachen.de; Krüger, Peter, ; Keusgen, Michael, ; Schöning, Michael Josef, schoening@fh-aachen.de Development and Electrochemical Investigations of an EIS-(Electrolyte-Insulator-Semiconductor) based Biosensor for Cyanide Detection 2007 11 Sensors 7 1424-8220 8 1415 1426 weltweit http://dx.doi.org/10.3390/s7081415 Fachbereich Chemie und Biotechnologie OPUS4-3775 Wissenschaftlicher Artikel Turek, Monika, ; Schöning, Michael Josef, schoening@fh-aachen.de; Kloock, Joachim P., kloock@fh-aachen.de; Schubert, Jürgen, ; Zander, Willi, ; Krüger, Peter, ; Keusgen, Michael, Herstellung und Charakterisierung eines hybriden Sensorarrays auf Halbleiterbasis für die Umweltanalytik Düsseldorf VDI-Verl. 2008 956 S. : Ill., graph. Darst. + 1 CD-ROM Sensoren und Messsysteme 2008 : 14. Fachtagung Ludwigsburg, 11. und 12. März 2008 / VDI/VDE-Gesellschaft Mess- und Automatisierungstechnik 978-3-18-092011-5 VDI-Berichte ; 2011 ; Sensoren und Messsysteme 2008, 14. GMA/ITG-Fachtagung, VDI/VDE- Gesellschaft Mess- und Automatisierungstechnik, + CD-ROM, Ludwigsburg, DE, 11.-12. Mar, 2008 803 810 Fachbereich Medizintechnik und Technomathematik OPUS4-3968 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Kirchner, Patrick, kirchner@fh-aachen.de; Ng, Yue Ann, ; Spelthahn, Heiko, spelthahn@fh-aachen.de; Schneider, Andreas, ; Henkel, Hartmut, ; Friedrich, Peter, ; Kolstad, Jens, ; Berger, Jörg, ; Keusgen, Michael, Gas sensor investigation based on a catalytically activated thin-film thermopile for H2O2 detection 2010 5 Physica Status Solidi (A). 207 (2010), H. 4 1862-6300 Special Issue: Engineering of Functional Interfaces EnFI 2009 787 792 campus http://dx.doi.org/10.1002/pssa.200983309 Fachbereich Medizintechnik und Technomathematik OPUS4-3969 Wissenschaftlicher Artikel Turek, Monik, ; Heiden, Wolfgang, ; Guo, Sharon, ; Riesen, Alfred, ; Schubert, Jürgen, ; Zander, Willi, ; Krüger, Peter, ; Keusgen, Michael, ; Schöning, Michael Josef, schoening@fh-aachen.de Simultaneous detection of cyanide and heavy metals for environmental analysis by means of µISEs 2010 6 Physica Status Solidi (A). 207 (2010), H. 4 1862-6300 Special Issue: Engineering of Functional Interfaces EnFI 2009 817 823 campus http://dx.doi.org/10.1002/pssa.200983303 Fachbereich Medizintechnik und Technomathematik OPUS4-4370 Wissenschaftlicher Artikel Kirchner, Patrick, kirchner@fh-aachen.de; Li, Bin, ; Spelthahn, Heiko, spelthahn@fh-aachen.de; Henkel, Hartmut, ; Schneider, Andreas, ; Friedrich, Peter, ; Kolstad, Jens, ; Keusgen, Michael, ; Schöning, Michael Josef, schoening@fh-aachen.de Thin-film calorimetric H2O2 gas sensor for the validation of germicidal effectivity in aseptic filling processes Amsterdam Elsevier 2011 6 Sensors and Actuators B: Chemical. 154 (2011), H. 2 1873-3077 EUROSENSORS XXIII 257 263 campus http://dx.doi.org/10.1016/j.snb.2010.01.058 Fachbereich Medizintechnik und Technomathematik OPUS4-4364 Wissenschaftlicher Artikel Kirchner, Patrick, kirchner@fh-aachen.de; Oberländer, Jan, oberlaender@fh-aachen.de; Friedrich, Peter, ; Berger, Jörg, ; Suso, Henri-Pierre, ; Kupyna, Andriy, ; Keusgen, Michael, ; Schöning, Michael Josef, schoening@fh-aachen.de Optimisation and fabrication of a calorimetric gas sensor built up on a polyimide substrate for H2O2 monitoring Weinheim Wiley 2011 5 Physica status solidi (a) : applications and material science. 208 (2011), H. 6 1862-6319 1235 1240 campus http://dx.doi.org/10.1002/pssa.201001132 Fachbereich Medizintechnik und Technomathematik OPUS4-4756 Wissenschaftlicher Artikel Kirchner, Patrick, kirchner@fh-aachen.de; Reisert, Steffen, reisert@fh-aachen.de; Pütz, Patrick, ; Keusgen, Michael, ; Schöning, Michael Josef, schoening@fh-aachen.de Characterisation of polymeric materials as passivation layer for calorimetric H2O2 gas sensors - 2012 4 Physica Status Solidi / A (2012) 1862-6319 5 859 863 campus http://dx.doi.org/10.1002/pssa.201100773 Fachbereich Medizintechnik und Technomathematik OPUS4-5122 Wissenschaftlicher Artikel Kirchner, Patrick, kirchner@fh-aachen.de; Oberländer, Jan, oberlaender@fh-aachen.de; Suso, Henri-Pierre, ; Rysstad, Gunnar, ; Keusgen, Michael, ; Schöning, Michael Josef, schoening@fh-aachen.de Towards a wireless sensor system for real-time H2O2 monitoring in aseptic food processes A wireless sensor system based on the industrial ZigBee standard for low-rate wireless networking was developed that enables real-time monitoring of gaseous H2O2 during the package sterilization in aseptic food processes. The sensor system consists of a remote unit connected to a calorimetric gas sensor, which was already established in former works, and an external base unit connected to a laptop computer. The remote unit was built up by an XBee radio frequency (RF) module for data communication and a programmable system-on-chip controller to read out the sensor signal and process the sensor data, whereas the base unit is a second XBee RF module. For the rapid H2O2 detection on various locations inside the package that has to be sterilized, a novel read-out strategy of the calorimetric gas sensor was established, wherein the sensor response is measured within the short sterilization time and correlated with the present H2O2 concentration. In an exemplary measurement application in an aseptic filling machinery, the suitability of the new, wireless sensor system was demonstrated, wherein the influence of the gas velocity on the H2O2 distribution inside a package was determined and verified with microbiological tests. Weinheim Wiley 2013 6 Physica status solidi (a) Vol. 210 Iss. 5 877 883 campus http://dx.doi.org/10.1002/pssa.201200920 Fachbereich Medizintechnik und Technomathematik OPUS4-5315 Wissenschaftlicher Artikel Werner, Frederik, f.werner@fh-aachen.de; Wagner, Torsten, torsten.wagner@fh-aachen.de; Yoshinobu, Tatsuo, ; Keusgen, Michael, ; Schöning, Michael Josef, schoening@fh-aachen.de Frequency behaviour of light-addressable potentiometric sensors Weinheim Wiley-VCH 2013 7 Physica Status Solidi (A). Vol. 210 (2013), iss. 5 884 891 campus http://onlinelibrary.wiley.com/doi/10.1002/pssa.201200929/pdf Fachbereich Medizintechnik und Technomathematik OPUS4-5384 Konferenzveröffentlichung Werner, Frederik, f.werner@fh-aachen.de; Mansour, Ahmed, ; Rateike, Franz-Matthias, rateike@fh-aachen.de; Schusser, Sebastian, schusser@fh-aachen.de; Wagner, Torsten, torsten.wagner@fh-aachen.de; Yoshinobu, Tatsuo, ; Keusgen, Michael, ; Schöning, Michael Josef, schoening@fh-aachen.de Gerlach, Gerald Kompakter Aufbau eines lichtadressierbaren potentiometrischen Sensors mit verfahrbarem Diodenlaser Dresden TUDpress 2011 3 10. Dresdner Sensor-Symposium : Dresden, 5. - 7. Dezember 2011 ; miniaturisierte analytische Verfahren, Hochtemperatur-Sensoren, Sensoren für Bioprozess- und Verfahrenstechnik, Sensoren für die Medizin, Chemische Verfahrenstechnik, Lebensmittelanalytik, innovative Sensorlösungen, Sensoren für die Wasserqualität, Selbstüberwachung / Gerald Gerlach ... (Hg.) Dresdner Beiträge zur Sensorik. 43 978-3-942710-53-4 277 280 weltweit http://dx.doi.org/10.5162/10dss2011/14.3 Fachbereich Energietechnik OPUS4-7075 Wissenschaftlicher Artikel Oberländer, Jan, oberlaender@fh-aachen.de; Bromm, Alexander, ; Wendeler, Luisa, ; Iken, Heiko, iken@fh-aachen.de; Palomar Duran, Marlena, ; Greeff, Anton, ; Kirchner, Patrick, kirchner@fh-aachen.de; Keusgen, Michael, ; Schöning, Michael Josef, schoening@fh-aachen.de Towards a biosensor to monitor the sterilisation efficiency of aseptic filling machines Weinheim Wiley 2015 6 Physica status solidi (a) 212 6 1299 1305 10.1002/pssa.201431900 Fachbereich Medizintechnik und Technomathematik OPUS4-7089 Wissenschaftlicher Artikel Pilas, Johanna, pilas@fh-aachen.de; Iken, Heiko, iken@fh-aachen.de; Selmer, Thorsten, selmer@fh-aachen.de; Keusgen, Michael, ; Schöning, Michael Josef, schoening@fh-aachen.de Development of a multi-parameter sensor chip for the simultaneous detection of organic compounds in biogas processes Weinheim Wiley 2015 6 Physica status solidi (a) 212 6 1306 1312 10.1002/pssa.201431894 Fachbereich Chemie und Biotechnologie OPUS4-7292 Wissenschaftlicher Artikel Molinnus, Denise, molinnus@fh-aachen.de; Bäcker, Matthias, baecker@fh-aachen.de; Iken, Heiko, iken@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de; Keusgen, Michael, ; Schöning, Michael Josef, schoening@fh-aachen.de Concept for a biomolecular logic chip with an integrated sensor and actuator function Weinheim Wiley 2015 6 Physica status solidi (a) 212 6 1382 1388 10.1002/pssa.201431913 Fachbereich Medizintechnik und Technomathematik OPUS4-7416 Wissenschaftlicher Artikel Oberländer, Jan, oberlaender@fh-aachen.de; Jildeh, Zaid B., ; Kirchner, Patrick, kirchner@fh-aachen.de; Wendeler, Luisa, ; Bromm, Alexander, ; Iken, Heiko, iken@fh-aachen.de; Wagner, Patrick, ; Keusgen, Michael, ; Schöning, Michael Josef, schoening@fh-aachen.de Study of Interdigitated Electrode Arrays Using Experiments and Finite Element Models for the Evaluation of Sterilization Processes Basel MDPI 2015 12 Sensors 15 10 26115 26127 10.3390/s151026115 Fachbereich Medizintechnik und Technomathematik OPUS4-7369 Wissenschaftlicher Artikel Bronder, Thomas, bronder@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de; Scheja, Sabrina, ; Wu, Chunsheng, C.Wu@fh-aachen.de; Keusgen, Michael, ; Mewes, Dieter, ; Schöning, Michael Josef, schoening@fh-aachen.de DNA Immobilization and Hybridization Detection by the Intrinsic Molecular Charge Using Capacitive Field-Effect Sensors Modified with a Charged Weak Polyelectrolyte Layer Washington, DC American Chemical Society 2015 7 Applied Materials & Interfaces 36 7 20068 20075 10.1021/acsami.5b05146 Fachbereich Medizintechnik und Technomathematik OPUS4-7590 Konferenzveröffentlichung Oberländer, Jan, oberlaender@fh-aachen.de; Jildeh, Zaid B., ; Kirchner, Patrick, kirchner@fh-aachen.de; Wendeler, Luisa, ; Bromm, Alexander, ; Iken, Heiko, iken@fh-aachen.de; Wagner, Patrick, ; Keusgen, Michael, ; Schöning, Michael Josef, schoening@fh-aachen.de Experimental and numerical evaluation of interdigitated electrode array for monitoring gaseous sterilization processes 2015 5 12. Dresdner Sensor-Symposium 2015 163 168 10.5162/12dss2015/P3.11 Fachbereich Medizintechnik und Technomathematik OPUS4-7593 Wissenschaftlicher Artikel Oberländer, Jan, oberlaender@fh-aachen.de; Kirchner, Patrick, kirchner@fh-aachen.de; Keusgen, Michael, ; Schöning, Michael Josef, schoening@fh-aachen.de Strategies in developing thin-film sensors for monitoring aseptic food processes : Theoretical considerations and investigations of passivation materials Amsterdam Elsevier 2015 6 Electrochimica Acta 183 130 136 10.1016/j.electacta.2015.06.126 Fachbereich Medizintechnik und Technomathematik OPUS4-7691 Wissenschaftlicher Artikel Arreola, Julio, arreola@fh-aachen.de; Mätzkow, Malte, ; Durán, Marlena Palomar, ; Greeff, Anton, ; Keusgen, Michael, ; Schöning, Michael Josef, schoening@fh-aachen.de Optimization of the immobilization of bacterial spores on glass substrates with organosilanes Spores can be immobilized on biosensors to function as sensitive recognition elements. However, the immobilization can affect the sensitivity and reproducibility of the sensor signal. In this work, three different immobilization strategies with organosilanes were optimized and characterized to immobilize Bacillus atrophaeus spores on glass substrates. Five different silanization parameters were investigated: nature of the solvent, concentration of the silane, silanization time, curing process, and silanization temperature. The resulting silane layers were resistant to a buffer solution (e.g., Ringer solution) with a polysorbate (e.g., Tween®80) and sonication. Weinheim Wiley-VCH 2016 7 Physica status solidi (A) : Applications and materials science 213 6 1463 1470 10.1002/pssa.201532914 campus https://doi.org/10.1002/pssa.201532914 Fachbereich Medizintechnik und Technomathematik OPUS4-7800 Wissenschaftlicher Artikel Wagner, Torsten, torsten.wagner@fh-aachen.de; Vornholt, Wolfgang, ; Werner, Frederik, f.werner@fh-aachen.de; Yoshinobu, Tatsuo, ; Miyamoto, Ko-Ichiro, ; Keusgen, Michael, ; Schöning, Michael Josef, schoening@fh-aachen.de Light-addressable potentiometric sensor (LAPS) combined with magnetic beads for pharmaceutical screening The light-addressable potentiometric sensor (LAPS) has the unique feature to address different regions of a sensor surface without the need of complex structures. Measurements at different locations on the sensor surface can be performed in a common analyte solution, which distinctly simplifies the fluidic set-up. However, the measurement in a single analyte chamber prevents the application of different drugs or different concentrations of a drug to each measurement spot at the same time as in the case of multi-reservoir-based set-ups. In this work, the authors designed a LAPS-based set-up for cell culture screening that utilises magnetic beads loaded with the endotoxin (lipopolysaccharides, LPS), to generate a spatially distributed gradient of analyte concentration. Different external magnetic fields can be adjusted to move the magnetic beads loaded with a specific drug within the measurement cell. By recording the metabolic activities of a cell layer cultured on top of the LAPS surface, this work shows the possibility to apply different concentrations of a sample along the LAPS measurement spots within a common analyte solution. 2016 5 Physics in medicine 2016 1 2 7 10.1016/j.phmed.2016.03.001 weltweit https://doi.org/10.1016/j.phmed.2016.03.001 Fachbereich Medizintechnik und Technomathematik OPUS4-7803 Wissenschaftlicher Artikel Molinnus, Denise, molinnus@fh-aachen.de; Sorich, Maren, ; Bartz, Alexander, ; Siegert, Petra, siegert@fh-aachen.de; Willenberg, Holger S., ; Lisdat, Fred, ; Poghossian, Arshak, poghossian@fh-aachen.de; Keusgen, Michael, ; Schöning, Michael Josef, schoening@fh-aachen.de Towards an adrenaline biosensor based on substrate recycling amplification in combination with an enzyme logic gate An amperometric biosensor using a substrate recycling principle was realized for the detection of low adrenaline concentrations (1 nM) by measurements in phosphate buffer and Ringer's solution at pH 6.5 and pH 7.4, respectively. In proof-of-concept experiments, a Boolean logic-gate principle has been applied to develop a digital adrenaline biosensor based on an enzyme AND logic gate. The obtained results demonstrate that the developed digital biosensor is capable for a rapid qualitative determination of the presence/absence of adrenaline in a YES/NO statement. Such digital biosensor could be used in clinical diagnostics for the control of a correct insertion of a catheter in the adrenal veins during adrenal venous-sampling procedure. Amsterdam Elsevier 2016 5 Sensors and Actuators B: Chemical 237 190 195 10.1016/j.snb.2016.06.064 bezahl https://doi.org/10.4028/10.1016/j.snb.2016.06.064 Fachbereich Chemie und Biotechnologie OPUS4-8046 Wissenschaftlicher Artikel Arreola, Julio, arreola@fh-aachen.de; Oberländer, Jan, oberlaender@fh-aachen.de; Mätzkow, M., ; Keusgen, Michael, ; Schöning, Michael Josef, schoening@fh-aachen.de Surface functionalization for spore-based biosensors with organosilanes Amsterdam Elsevier 2017 Electromchimica Acta In Press, Accepted Manuscript 10.1016/j.electacta.2017.04.157 Fachbereich Medizintechnik und Technomathematik OPUS4-8047 Wissenschaftlicher Artikel Bronder, Thomas, bronder@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de; Keusgen, Michael, ; Schöning, Michael Josef, schoening@fh-aachen.de Label-free detection of double-stranded DNA molecules with polyelectrolyte-modified capacitive field-effect sensors Oldenbourg De Gruyter 2017 6 tm - Technisches Messen 84 10 628 634 10.1515/teme-2017-0015 Fachbereich Medizintechnik und Technomathematik OPUS4-8132 Konferenzveröffentlichung Oberländer, Jan, oberlaender@fh-aachen.de; Arreola, Julio, arreola@fh-aachen.de; Hansen, Christina, ; Greeff, Anton, ; Mayer, Marlena, ; Keusgen, Michael, ; Schöning, Michael Josef, schoening@fh-aachen.de Impedimetric Biosensor to Enable Fast Evaluation of Gaseous Sterilization Processes 2017 4 Seiten MDPI Proceedings 1 Eurosensors 2017 Conference, Paris, France, 3-6 September 2017 4 10.3390/proceedings1040435 Fachbereich Medizintechnik und Technomathematik OPUS4-8133 Konferenzveröffentlichung Molinnus, Denise, molinnus@fh-aachen.de; Hardt, Gabriel, ; Käver, Larissa, ; Willenberg, Holger S., ; Poghossian, Arshak, poghossian@fh-aachen.de; Keusgen, Michael, ; Schöning, Michael Josef, schoening@fh-aachen.de Detection of Adrenaline Based on Bioelectrocatalytical System to Support Tumor Diagnostic Technology 2017 4 Seiten MDPI Proceedings Eurosensors 2017 Conference, Paris, France, 3-6 September 2017 10.3390/proceedings1040506 Fachbereich Medizintechnik und Technomathematik OPUS4-8141 Wissenschaftlicher Artikel Molinnus, Denise, molinnus@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de; Keusgen, Michael, ; Katz, Evgeny, ; Schöning, Michael Josef, schoening@fh-aachen.de Coupling of Biomolecular Logic Gates with Electronic Transducers: From Single Enzyme Logic Gates to Sense/Act/Treat Chips Weinheim Wiley 2017 9 Electroanalysis 29 8 1840 1849 10.1002/elan.201700208 Fachbereich Medizintechnik und Technomathematik OPUS4-8145 Wissenschaftlicher Artikel Arreola, Julio, arreola@fh-aachen.de; Keusgen, Michael, ; Schöning, Michael Josef, schoening@fh-aachen.de Effect of O2 plasma on properties of electrolyte-insulator-semiconductor structures Weinheim Wiley-VCH 2017 physica status solidi a : applications and materials sciences Early view 10.1002/pssa.201700025 Fachbereich Medizintechnik und Technomathematik OPUS4-8158 Wissenschaftlicher Artikel Pilas, Johanna, pilas@fh-aachen.de; Yazici, Yasemen, ; Selmer, Thorsten, selmer@fh-aachen.de; Keusgen, Michael, ; Schöning, Michael Josef, schoening@fh-aachen.de Optimization of an amperometric biosensor array for simultaneous measurement of ethanol, formate, d- and l-lactate Amsterdam Elsevier 2017 6 Electrochimica Acta 251 256 262 10.1016/j.electacta.2017.07.119 Fachbereich Chemie und Biotechnologie OPUS4-8296 Wissenschaftlicher Artikel Molinnus, Denise, molinnus@fh-aachen.de; Hardt, Gabriel, ; Siegert, Petra, siegert@fh-aachen.de; Willenberg, Holger S., ; Poghossian, Arshak, poghossian@fh-aachen.de; Keusgen, Michael, ; Schöning, Michael Josef, schoening@fh-aachen.de Detection of Adrenaline in Blood Plasma as Biomarker for Adrenal Venous Sampling An amperometric bi-enzyme biosensor based on substrate recycling principle for the amplification of the sensor signal has been developed for the detection of adrenaline in blood. Adrenaline can be used as biomarker verifying successful adrenal venous sampling procedure. The adrenaline biosensor has been realized via modification of a galvanic oxygen sensor with a bi-enzyme membrane combining a genetically modified laccase and a pyrroloquinoline quinone-dependent glucose dehydrogenase. The measurement conditions such as pH value and temperature were optimized to enhance the sensor performance. A high sensitivity and a low detection limit of about 0.5-1 nM adrenaline have been achieved in phosphate buffer at pH 7.4, relevant for measurements in blood samples. The sensitivity of the biosensor to other catecholamines such as noradrenaline, dopamine and dobutamine has been studied. Finally, the sensor has been successfully applied for the detection of adrenaline in human blood plasma. Weinheim Wiley-VCH 2018 5 Electroanalysis 30 5 937 942 10.1002/elan.201800026 campus http://doi.org/10.1002/elan.201800026 Fachbereich Medizintechnik und Technomathematik OPUS4-8253 Wissenschaftlicher Artikel Oberländer, Jan, oberlaender@fh-aachen.de; Mayer, Marlena, ; Greeff, Anton, ; Keusgen, Michael, ; Schöning, Michael Josef, schoening@fh-aachen.de Spore-based biosensor to monitor the microbicidal efficacy of gaseous hydrogen peroxide sterilization processes In this work, a spore-based biosensor is evaluated to monitor the microbicidal efficacy of sterilization processes applying gaseous hydrogen peroxide (H2O2). The sensor is based on interdigitated electrode structures (IDEs) that have been fabricated by means of thin-film technologies. Impedimetric measurements are applied to study the effect of sterilization process on spores of Bacillus atrophaeus. This resilient microorganism is commonly used in industry to proof the sterilization efficiency. The sensor measurements are accompanied by conventional microbiological challenge tests, as well as morphological characterizations with scanning electron microscopy (SEM) and transmission electron microscopy (TEM). The sensor measurements are correlated with the microbiological test routines. In both methods, namely the sensor-based and microbiological one, a tailing effect has been observed. The results are evaluated and discussed in a three-dimensional calibration plot demonstrating the sensor's suitability to enable a rapid process decision in terms of a successfully performed sterilization. Amsterdam Elsevier 2018 7 Biosensors and Bioelectronics 104 87 94 10.1016/j.bios.2017.12.045 bezahl https://doi.org/10.1016/j.bios.2017.12.045 Fachbereich Medizintechnik und Technomathematik OPUS4-8418 Wissenschaftlicher Artikel Molinnus, Denise, molinnus@fh-aachen.de; Muschallik, Lukas, muschallik@fh-aachen.de; Gonzalez, Laura Osorio, ; Bongaerts, Johannes, bongaerts@fh-aachen.de; Wagner, Torsten, torsten.wagner@fh-aachen.de; Selmer, Thorsten, selmer@fh-aachen.de; Siegert, Petra, siegert@fh-aachen.de; Keusgen, Michael, ; Schöning, Michael Josef, schoening@fh-aachen.de Development and characterization of a field-effect biosensor for the detection of acetoin A capacitive electrolyte-insulator-semiconductor (EIS) field-effect biosensor for acetoin detection has been presented for the first time. The EIS sensor consists of a layer structure of Al/p-Si/SiO₂/Ta₂O₅/enzyme acetoin reductase. The enzyme, also referred to as butane-2,3-diol dehydrogenase from B. clausii DSM 8716T, has been recently characterized. The enzyme catalyzes the (R)-specific reduction of racemic acetoin to (R,R)- and meso-butane-2,3-diol, respectively. Two different enzyme immobilization strategies (cross-linking by using glutaraldehyde and adsorption) have been studied. Typical biosensor parameters such as optimal pH working range, sensitivity, hysteresis, linear concentration range and long-term stability have been examined by means of constant-capacitance (ConCap) mode measurements. Furthermore, preliminary experiments have been successfully carried out for the detection of acetoin in diluted white wine samples. Amsterdam Elsevier 2018 5 Biosensors and Bioelectronics 115 1 6 10.1016/j.bios.2018.05.023 bezahl https://doi.org/10.1016/j.bios.2018.05.023 Fachbereich Chemie und Biotechnologie OPUS4-8425 Wissenschaftlicher Artikel Molinnus, Denise, molinnus@fh-aachen.de; Hardt, G., ; Käver, L., ; Willenberg, H.S., ; Kröger, J.-C., ; Poghossian, Arshak, poghossian@fh-aachen.de; Keusgen, Michael, ; Schöning, Michael Josef, schoening@fh-aachen.de Chip-based biosensor for the detection of low adrenaline concentrations to support adrenal venous sampling A chip-based amperometric biosensor referring on using the bioelectrocatalytical amplification principle for the detection of low adrenaline concentrations is presented. The adrenaline biosensor has been prepared by modification of a platinum thin-film electrode with an enzyme membrane containing the pyrroloquinoline quinone-dependent glucose dehydrogenase and glutaraldehyde. Measuring conditions such as temperature, pH value, and glucose concentration have been optimized to achieve a high sensitivity and a low detection limit of about 1 nM adrenaline measured in phosphate buffer at neutral pH value. The response of the biosensor to different catecholamines has also been proven. Long-term stability of the adrenaline biosensor has been studied over 10 days. In addition, the biosensor has been successfully applied for adrenaline detection in human blood plasma for future biomedical applications. Furthermore, preliminary experiments have been carried to detect the adrenaline-concentration difference measured in peripheral blood and adrenal venous blood, representing the adrenal vein sampling procedure of a physician. Amsterdam Elsevier 2018 6 Sensor and Actuators B: Chemical 272 21 27 10.1016/j.snb.2018.05.136 bezahl https://doi.org/10.1016/j.snb.2018.05.136 Fachbereich Medizintechnik und Technomathematik OPUS4-8435 Wissenschaftlicher Artikel Bronder, Thomas, bronder@fh-aachen.de; Jessing, Max P., ; Poghossian, Arshak, poghossian@fh-aachen.de; Keusgen, Michael, ; Schöning, Michael Josef, schoening@fh-aachen.de Detection of PCR-Amplified Tuberculosis DNA Fragments with Polyelectrolyte-Modified Field-Effect Sensors Field-effect-based electrolyte-insulator-semiconductor (EIS) sensors were modified with a bilayer of positively charged weak polyelectrolyte (poly(allylamine hydrochloride) (PAH)) and probe single-stranded DNA (ssDNA) and are used for the detection of complementary single-stranded target DNA (cDNA) in different test solutions. The sensing mechanism is based on the detection of the intrinsic molecular charge of target cDNA molecules after the hybridization event between cDNA and immobilized probe ssDNA. The test solutions contain synthetic cDNA oligonucleotides (with a sequence of tuberculosis mycobacteria genome) or PCR-amplified DNA (which origins from a template DNA strand that has been extracted from Mycobacterium avium paratuberculosis-spiked human sputum samples), respectively. Sensor responses up to 41 mV have been measured for the test solutions with DNA, while only small signals of ∼5 mV were detected for solutions without DNA. The lower detection limit of the EIS sensors was ∼0.3 nM, and the sensitivity was ∼7.2 mV/decade. Fluorescence experiments using SybrGreen I fluorescence dye support the electrochemical results. Washington, DC ACS Publications 2018 6 Analytical Chemistry 90 article in press 12 7747 7753 10.1021/acs.analchem.8b01807 campus https://doi.org/10.1021/acs.analchem.8b01807 Fachbereich Medizintechnik und Technomathematik OPUS4-8436 Wissenschaftlicher Artikel Jildeh, Zaid B., ; Oberländer, Jan, oberlaender@fh-aachen.de; Kirchner, Patrick, kirchner@fh-aachen.de; Keusgen, Michael, ; Wagner, Patrick H., ; Schöning, Michael Josef, schoening@fh-aachen.de Experimental and Numerical Analyzes of a Sensor Based on Interdigitated Electrodes for Studying Microbiological Alterations In this work, a cell-based biosensor to evaluate the sterilization efficacy of hydrogen peroxide vapor sterilization processes is characterized. The transducer of the biosensor is based on interdigitated gold electrodes fabricated on an inert glass substrate. Impedance spectroscopy is applied to evaluate the sensor behavior and the alteration of test microorganisms due to the sterilization process. These alterations are related to changes in relative permittivity and electrical conductivity of the bacterial spores. Sensor measurements are conducted with and without bacterial spores (Bacillus atrophaeus), as well as after an industrial sterilization protocol. Equivalent two-dimensional numerical models based on finite element method of the periodic finger structures of the interdigitated gold electrodes are designed and validated using COMSOL® Multiphysics software by the application of known dielectric properties. The validated models are used to compute the electrical properties at different sensor states (blank, loaded with spores, and after sterilization). As a final result, we will derive and tabulate the frequency-dependent electrical parameters of the spore layer using a novel model that combines experimental data with numerical optimization techniques. Weinheim Wiley-VCH 2018 9 Seiten physica status solidi (a): applications and materials science 215 15 Article number 1700920 10.1002/pssa.201700920 campus https://doi.org/10.1002/pssa.201700920 Fachbereich Medizintechnik und Technomathematik OPUS4-10677 Wissenschaftlicher Artikel Janus, Kevin Alexander, janus@fh-aachen.de; Achtsnicht, Stefan, achtsnicht@fh-aachen.de; Tempel, Laura, ; Drinic, Aleksaner, ; Kopp, Alexander, ; Keusgen, Michael, ; Schöning, Michael Josef, Schoening@fh-aachen.de Influence of fibroin membrane composition and curing parameters on the performance of a biodegradable enzymatic biosensor manufactured from Silicon-Free Carbon Herein, fibroin, polylactide (PLA), and carbon are investigated for their suitability as biocompatible and biodegradable materials for amperometric biosensors. For this purpose, screen-printed carbon electrodes on the biodegradable substrates fibroin and PLA are modified with a glucose oxidase membrane and then encapsulated with the biocompatible material Ecoflex. The influence of different curing parameters of the carbon electrodes on the resulting biosensor characteristics is studied. The morphology of the electrodes is investigated by scanning electron microscopy, and the biosensor performance is examined by amperometric measurements of glucose (0.5-10 mM) in phosphate buffer solution, pH 7.4, at an applied potential of 1.2 V versus a Ag/AgCl reference electrode. Instead of Ecoflex, fibroin, PLA, and wound adhesive are tested as alternative encapsulation compounds: a series of swelling tests with different fibroin compositions, PLA, and Ecoflex has been performed before characterizing the most promising candidates by chronoamperometry. Therefore, the carbon electrodes are completely covered with the particular encapsulation material. Chronoamperometric measurements with H2O2 concentrations between 0.5 and 10 mM enable studying the leakage current behavior. Weinheim Wiley-VCH 2023 10 Seiten Physica status solidi : pss. A, Applications and materials science 220 Corresponding author: Michael J. Schöning 22 10.1002/pssa.202300081 weltweit https://doi.org/10.1002/pssa.202300081 Fachbereich Medizintechnik und Technomathematik OPUS4-10927 Wissenschaftlicher Artikel Janus, Kevin Alexander, janus@fh-aachen.de; Achtsnicht, Stefan, achtsnicht@fh-aachen.de; Drinic, Aleksander, ; Kopp, Alexander, ; Keusgen, Michael, ; Schöning, Michael Josef, schoening@fh-aachen.de Transient magnesium-based thin-film temperature sensor on a flexible, bioabsorbable substrate for future medical applications In this work, the bioabsorbable materials, namely fibroin, polylactide acid (PLA), magnesium and magnesium oxide are investigated for their application as transient, resistive temperature detectors (RTD). For this purpose, a thin-film magnesium-based meander-like electrode is deposited onto a flexible, bioabsorbable substrate (fibroin or PLA) and encapsulated (passivated) by additional magnesium oxide layers on top and below the magnesium-based electrode. The morphology of different layered RTDs is analyzed by scanning electron microscopy. The sensor performance and lifetime of the RTD is characterized both under ambient atmospheric conditions between 30°C and 43°C, and wet tissue-like conditions with a constant temperature regime of 37°C. The latter triggers the degradation process of the magnesium-based layers. The 3-layers RTDs on a PLA substrate could achieve a lifetime of 8.5 h. These sensors also show the best sensor performance under ambient atmospheric conditions with a mean sensitivity of 0.48 Ω/°C ± 0.01 Ω/°C. Wiley-VCH 2023 22 Seiten Applied Research Corresponding author: Michael Josef Schöning Accepted manuscript 10.1002/appl.202300102 weltweit https://doi.org/10.1002/appl.202300102 Fachbereich Medizintechnik und Technomathematik OPUS4-8787 Wissenschaftlicher Artikel Arreola, Julio, arreola@fh-aachen.de; Keusgen, Michael, ; Schöning, Michael Josef, schoening@fh-aachen.de Toward an immobilization method for spore-based biosensors in oxidative environment Amsterdam Elsevier 2019 7 Electrochimica Acta 302 394 401 10.1016/j.electacta.2019.01.148 bezahl https://doi.org/10.1016/j.electacta.2019.01.148 Fachbereich Medizintechnik und Technomathematik OPUS4-8796 Wissenschaftlicher Artikel Bronder, Thomas, bronder@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de; Jessing, Max P., ; Keusgen, Michael, ; Schöning, Michael Josef, schoening@fh-aachen.de Surface regeneration and reusability of label-free DNA biosensors based on weak polyelectrolyte-modified capacitive field-effect structures Amsterdam Elsevier 2019 7 Biosensors and Bioelectronics 126 510 517 10.1016/j.bios.2018.11.019 bezahl https://doi.org/10.1016/j.bios.2018.11.019 Fachbereich Medizintechnik und Technomathematik OPUS4-9087 Wissenschaftlicher Artikel Arreola, Julio, arreola@fh-aachen.de; Keusgen, Michael, ; Wagner, Torsten, torsten.wagner@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de Combined calorimetric gas- and spore-based biosensor array for online monitoring and sterility assurance of gaseous hydrogen peroxide in aseptic filling machines Amsterdam Elsevier 2019 Biosensors and Bioelectronics 143 111628 10.1016/j.bios.2019.111628 bezahl https://doi.org/10.1016/j.bios.2019.111628 Fachbereich Medizintechnik und Technomathematik OPUS4-10529 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Bronder, Thomas, bronder@fh-aachen.de; Wu, Chunsheng, C.Wu@fh-aachen.de; Scheja, Sabrina, ; Jessing, Max, ; Metzger-Boddien, Christoph, ; Keusgen, Michael, ; Poghossian, Arshak, poghossian@fh-aachen.de Label-Free DNA Detection with Capacitive Field-Effect Devices—Challenges and Opportunities Field-effect EIS (electrolyte-insulator-semiconductor) sensors modified with a positively charged weak polyelectrolyte layer have been applied for the electrical detection of DNA (deoxyribonucleic acid) immobilization and hybridization by the intrinsic molecular charge. The EIS sensors are able to detect the existence of target DNA amplicons in PCR (polymerase chain reaction) samples and thus, can be used as tool for a quick verification of DNA amplification and the successful PCR process. Due to their miniaturized setup, compatibility with advanced micro- and nanotechnologies, and ability to detect biomolecules by their intrinsic molecular charge, those sensors can serve as possible platform for the development of label-free DNA chips. Possible application fields as well as challenges and limitations will be discussed. Basel MDPI 2017 Proceedings 1 This article belongs to the Proceedings of "Proceedings of the 5th International Symposium on Sensor Science (I3S 2017)" 8 Artikel 719 10.3390/proceedings1080719 weltweit https://doi.org/10.3390/proceedings1080719 Fachbereich Medizintechnik und Technomathematik OPUS4-10520 Wissenschaftlicher Artikel Welden, Melanie, ; Poghossian, Arshak, ; Vahidpour, Farnoosh, vahidpour@fh-aachen.de; Wendlandt, Tim, ; Keusgen, Michael, ; Wege, Christina, ; Schöning, Michael Josef, schoening@fh-aachen.de Towards multi-analyte detection with field-effect capacitors modified with tobacco mosaic virus bioparticles as enzyme nanocarriers Utilizing an appropriate enzyme immobilization strategy is crucial for designing enzyme-based biosensors. Plant virus-like particles represent ideal nanoscaffolds for an extremely dense and precise immobilization of enzymes, due to their regular shape, high surface-to-volume ratio and high density of surface binding sites. In the present work, tobacco mosaic virus (TMV) particles were applied for the co-immobilization of penicillinase and urease onto the gate surface of a field-effect electrolyte-insulator-semiconductor capacitor (EISCAP) with a p-Si-SiO₂-Ta₂O₅ layer structure for the sequential detection of penicillin and urea. The TMV-assisted bi-enzyme EISCAP biosensor exhibited a high urea and penicillin sensitivity of 54 and 85 mV/dec, respectively, in the concentration range of 0.1-3 mM. For comparison, the characteristics of single-enzyme EISCAP biosensors modified with TMV particles immobilized with either penicillinase or urease were also investigated. The surface morphology of the TMV-modified Ta₂O₅-gate was analyzed by scanning electron microscopy. Additionally, the bi-enzyme EISCAP was applied to mimic an XOR (Exclusive OR) enzyme logic gate. Basel MDPI 2022 Biosensors 12 This article belongs to the Special Issue "Biosensors: 10th Anniversary Feature Papers" 1 10.3390/bios12010043 weltweit https://doi.org/10.3390/bios12010043 Fachbereich Chemie und Biotechnologie OPUS4-10521 Wissenschaftlicher Artikel Welden, Rene, welden@fh-aachen.de; Jablonski, Melanie, ; Wege, Christina, ; Keusgen, Michael, ; Wagner, Patrick Hermann, ; Wagner, Torsten, torsten.wagner@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de Light-Addressable Actuator-Sensor Platform for Monitoring and Manipulation of pH Gradients in Microfluidics: A Case Study with the Enzyme Penicillinase The feasibility of light-addressed detection and manipulation of pH gradients inside an electrochemical microfluidic cell was studied. Local pH changes, induced by a light-addressable electrode (LAE), were detected using a light-addressable potentiometric sensor (LAPS) with different measurement modes representing an actuator-sensor system. Biosensor functionality was examined depending on locally induced pH gradients with the help of the model enzyme penicillinase, which had been immobilized in the microfluidic channel. The surface morphology of the LAE and enzyme-functionalized LAPS was studied by scanning electron microscopy. Furthermore, the penicillin sensitivity of the LAPS inside the microfluidic channel was determined with regard to the analyte's pH influence on the enzymatic reaction rate. In a final experiment, the LAE-controlled pH inhibition of the enzyme activity was monitored by the LAPS. Basel MDPI 2021 Artikel 171 Biosensors 11 This article belongs to the Special Issue "Selected Papers from the 1st International Electronic Conference on Biosensors (IECB 2020)" 6 10.3390/bios11060171 weltweit https://doi.org/10.3390/bios11060171 Fachbereich Chemie und Biotechnologie OPUS4-10515 Wissenschaftlicher Artikel Welden, Melanie, ; Severins, Robin, ; Poghossian, Arshak, ; Wege, Christina, ; Bongaerts, Johannes, bongaerts@fh-aachen.de; Siegert, Petra, siegert@fh-aachen.de; Keusgen, Michael, ; Schöning, Michael Josef, schoening@fh-aachen.de Detection of acetoin and diacetyl by a tobacco mosaic virus-assisted field-effect biosensor Acetoin and diacetyl have a major impact on the flavor of alcoholic beverages such as wine or beer. Therefore, their measurement is important during the fermentation process. Until now, gas chromatographic techniques have typically been applied; however, these require expensive laboratory equipment and trained staff, and do not allow for online monitoring. In this work, a capacitive electrolyte-insulator-semiconductor sensor modified with tobacco mosaic virus (TMV) particles as enzyme nanocarriers for the detection of acetoin and diacetyl is presented. The enzyme acetoin reductase from Alkalihalobacillus clausii DSM 8716ᵀ is immobilized via biotin-streptavidin affinity, binding to the surface of the TMV particles. The TMV-assisted biosensor is electrochemically characterized by means of leakage-current, capacitance-voltage, and constant capacitance measurements. In this paper, the novel biosensor is studied regarding its sensitivity and long-term stability in buffer solution. Moreover, the TMV-assisted capacitive field-effect sensor is applied for the detection of diacetyl for the first time. The measurement of acetoin and diacetyl with the same sensor setup is demonstrated. Finally, the successive detection of acetoin and diacetyl in buffer and in diluted beer is studied by tuning the sensitivity of the biosensor using the pH value of the measurement solution. Basel MDPI 2022 Chemosensors 10 This article belongs to the Special Issue "Nanostructured Devices for Biochemical Sensing" 6 10.3390/chemosensors10060218 weltweit https://doi.org/10.3390/chemosensors10060218 Fachbereich Chemie und Biotechnologie OPUS4-10516 Konferenzveröffentlichung Welden, Melanie, ; Severins, Robin, severins@fh-aachen.de; Poghossian, Arshak, ; Wege, Christina, ; Siegert, Petra, siegert@fh-aachen.de; Keusgen, Michael, ; Schöning, Michael Josef, schoening@fh-aachen.de Studying the immobilization of acetoin reductase with Tobacco mosaic virus particles on capacitive field-effect sensors A capacitive electrolyte-insulator-semiconductor (EISCAP) biosensor modified with Tobacco mosaic virus (TMV) particles for the detection of acetoin is presented. The enzyme acetoin reductase (AR) was immobilized on the surface of the EISCAP using TMV particles as nanoscaffolds. The study focused on the optimization of the TMV-assisted AR immobilization on the Ta 2 O 5 -gate EISCAP surface. The TMV-assisted acetoin EISCAPs were electrochemically characterized by means of leakage-current, capacitance-voltage, and constant-capacitance measurements. The TMV-modified transducer surface was studied via scanning electron microscopy. IEEE 2022 4 Seiten 2022 IEEE International Symposium on Olfaction and Electronic Nose (ISOEN) 978-1-6654-5860-3 (Online) IEEE International Symposium on Olfaction and Electronic Nose (ISOEN), 29 May 2022 - 01 June 2022, Aveiro, Portugal. 10.1109/ISOEN54820.2022.9789657 campus https://doi.org/10.1109/ISOEN54820.2022.9789657 Fachbereich Medizintechnik und Technomathematik OPUS4-8603 Wissenschaftlicher Artikel Röhlen, Desiree, roehlen@fh-aachen.de; Pilas, Johanna, pilas@fh-aachen.de; Dahmen, Markus, dahmen@fh-aachen.de; Keusgen, Michael, ; Selmer, Thorsten, selmer@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de Toward a Hybrid Biosensor System for Analysis of Organic and Volatile Fatty Acids in Fermentation Processes Monitoring of organic acids (OA) and volatile fatty acids (VFA) is crucial for the control of anaerobic digestion. In case of unstable process conditions, an accumulation of these intermediates occurs. In the present work, two different enzyme-based biosensor arrays are combined and presented for facile electrochemical determination of several process-relevant analytes. Each biosensor utilizes a platinum sensor chip (14 × 14 mm²) with five individual working electrodes. The OA biosensor enables simultaneous measurement of ethanol, formate, d- and l-lactate, based on a bi-enzymatic detection principle. The second VFA biosensor provides an amperometric platform for quantification of acetate and propionate, mediated by oxidation of hydrogen peroxide. The cross-sensitivity of both biosensors toward potential interferents, typically present in fermentation samples, was investigated. The potential for practical application in complex media was successfully demonstrated in spiked sludge samples collected from three different biogas plants. Thereby, the results obtained by both of the biosensors were in good agreement to the applied reference measurements by photometry and gas chromatography, respectively. The proposed hybrid biosensor system was also used for long-term monitoring of a lab-scale biogas reactor (0.01 m³) for a period of 2 months. In combination with typically monitored parameters, such as gas quality, pH and FOS/TAC (volatile organic acids/total anorganic carbonate), the amperometric measurements of OA and VFA concentration could enhance the understanding of ongoing fermentation processes. Lausanne Frontiers 2018 10 Frontiers in Chemistry 6 Article 284 1 11 10.3389/fchem.2018.00284 weltweit http://doi.org/10.3389/fchem.2018.00284 Fachbereich Chemie und Biotechnologie OPUS4-8906 Wissenschaftlicher Artikel Cornelis, Peter, ; Givanoudi, Stella, ; Yongabi, Derick, ; Iken, Heiko, iken@fh-aachen.de; Duwé, Sam, ; Deschaume, Olivier, ; Robbens, Johan, ; Dedecker, Peter, ; Bartic, Carmen, ; Wübbenhorst, Michael, ; Schöning, Michael Josef, schoening@fh-aachen.de; Heyndrickx, Marc, ; Wagner, Patrick, Sensitive and specific detection of E. coli using biomimetic receptors in combination with a modified heat-transfer method Amsterdam Elsevier 2019 8 Biosensors and Bioelectronics 136 97 105 10.1016/j.bios.2019.04.026 bezahl https://doi.org/10.1016/j.bios.2019.04.026 Fachbereich Medizintechnik und Technomathematik OPUS4-9213 Wissenschaftlicher Artikel Pilas, Johanna, pilas@fh-aachen.de; Selmer, Thorsten, selmer@fh-aachen.de; Keusgen, Michael, ; Schöning, Michael Josef, schoening@fh-aachen.de Screen-printed carbon electrodes modified with graphene oxide for the design of a reagent-free NAD+-dependent biosensor array 2019 6 Analytical Chemistry 91 23 15293 15299 10.1021/acs.analchem.9b04481 campus https://doi.org/10.1021/acs.analchem.9b04481 Fachbereich Medizintechnik und Technomathematik OPUS4-9548 Wissenschaftlicher Artikel Wert, Stefan, ; Iken, Heiko, iken@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de; Matysik, Frank-Michael, Development of a temperature-pulse enhanced electrochemical glucose biosensor and characterization of its stability via scanning electrochemical microscopy Glucose oxidase (GOx) is an enzyme frequently used in glucose biosensors. As increased temperatures can enhance the performance of electrochemical sensors, we investigated the impact of temperature pulses on GOx that was drop-coated on flattened Pt microwires. The wires were heated by an alternating current. The sensitivity towards glucose and the temperature stability of GOx was investigated by amperometry. An up to 22-fold increase of sensitivity was observed. Spatially resolved enzyme activity changes were investigated via scanning electrochemical microscopy. The application of short (<100 ms) heat pulses was associated with less thermal inactivation of the immobilized GOx than long-term heating. Weinheim Wiley-VCH 2021 Electroanalysis Early View 10.1002/elan.202100089 weltweit https://doi.org/10.1002/elan.202100089 Fachbereich Medizintechnik und Technomathematik OPUS4-9509 Wissenschaftlicher Artikel Jablonski, Melanie, m.jablosnki@fh-aachen.de; Münstermann, Felix, ; Nork, Jasmina, ; Molinnus, Denise, Molinnus@fh-aachen.de; Muschallik, Lukas, muschallik@fh-aachen.de; Bongaerts, Johannes, bongaerts@fh-aachen.de; Wagner, Torsten, torsten.wagner@fh-aachen.de; Keusgen, Michael, ; Siegert, Petra, siegert@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de Capacitive field-effect biosensor applied for the detection of acetoin in alcoholic beverages and fermentation broths An acetoin biosensor based on a capacitive electrolyte-insulator-semiconductor (EIS) structure modified with the enzyme acetoin reductase, also known as butane-2,3-diol dehydrogenase (Bacillus clausii DSM 8716ᵀ), is applied for acetoin detection in beer, red wine, and fermentation broth samples for the first time. The EIS sensor consists of an Al/p-Si/SiO₂/Ta₂O₅ layer structure with immobilized acetoin reductase on top of the Ta₂O₅ transducer layer by means of crosslinking via glutaraldehyde. The unmodified and enzyme-modified sensors are electrochemically characterized by means of leakage current, capacitance-voltage, and constant capacitance methods, respectively. Weinheim Wiley-VCH 2021 7 Seiten physica status solidi (a) applications and materials science 218 13 10.1002/pssa.202000765 weltweit https://doi.org/10.1002/pssa.202000765 Fachbereich Chemie und Biotechnologie OPUS4-9491 Wissenschaftlicher Artikel Jablonski, Melanie, m.jablonski@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de; Severin, Robin, ; Keusgen, Michael, ; Wege, Christian, ; Schöning, Michael Josef, schoening@fh-aachen.de Capacitive Field-Effect Biosensor Studying Adsorption of Tobacco Mosaic Virus Particles Plant virus-like particles, and in particular, tobacco mosaic virus (TMV) particles, are increasingly being used in nano- and biotechnology as well as for biochemical sensing purposes as nanoscaffolds for the high-density immobilization of receptor molecules. The sensitive parameters of TMV-assisted biosensors depend, among others, on the density of adsorbed TMV particles on the sensor surface, which is affected by both the adsorption conditions and surface properties of the sensor. In this work, Ta₂O₅-gate field-effect capacitive sensors have been applied for the label-free electrical detection of TMV adsorption. The impact of the TMV concentration on both the sensor signal and the density of TMV particles adsorbed onto the Ta₂O₅-gate surface has been studied systematically by means of field-effect and scanning electron microscopy methods. In addition, the surface density of TMV particles loaded under different incubation times has been investigated. Finally, the field-effect sensor also demonstrates the label-free detection of penicillinase immobilization as model bioreceptor on TMV particles. MDPI 2021 15 Micromachines 12 1 1 16 10.3390/mi12010057 weltweit https://doi.org/10.3390/mi12010057 Fachbereich Medizintechnik und Technomathematik OPUS4-9965 Wissenschaftlicher Artikel Jablonski, Melanie, m.jablosnki@fh-aachen.de; Poghossian, Arshak, ; Keusgen, Michael, ; Wege, Christina, ; Schöning, Michael Josef, schoening@fh-aachen.de Detection of plant virus particles with a capacitive field-effect sensor Plant viruses are major contributors to crop losses and induce high economic costs worldwide. For reliable, on-site and early detection of plant viral diseases, portable biosensors are of great interest. In this study, a field-effect SiO2-gate electrolyte-insulator-semiconductor (EIS) sensor was utilized for the label-free electrostatic detection of tobacco mosaic virus (TMV) particles as a model plant pathogen. The capacitive EIS sensor has been characterized regarding its TMV sensitivity by means of constant-capacitance method. The EIS sensor was able to detect biotinylated TMV particles from a solution with a TMV concentration as low as 0.025 nM. A good correlation between the registered EIS sensor signal and the density of adsorbed TMV particles assessed from scanning electron microscopy images of the SiO2-gate chip surface was observed. Additionally, the isoelectric point of the biotinylated TMV particles was determined via zeta potential measurements and the influence of ionic strength of the measurement solution on the TMV-modified EIS sensor signal has been studied. Cham Springer Nature 2021 9 Analytical and Bioanalytical Chemistry 413 Corresponding authors: Arshak Poghossian & Michael J. Schöning 5669 5678 10.1007/s00216-021-03448-8 weltweit https://doi.org/10.1007/s00216-021-03448-8 Fachbereich Medizintechnik und Technomathematik OPUS4-10235 Wissenschaftlicher Artikel Molinnus, Denise, Molinnus@fh-aachen.de; Janus, Kevin Alexander, janus@fh-aachen.de; Fang, Anyelina C., ; Drinic, Aleksander, ; Achtsnicht, Stefan, achtsnicht@fh-aachen.de; Köpf, Marius, ; Keusgen, Michael, ; Schöning, Michael Josef, schoening@fh-aachen.de Thick-film carbon electrode deposited onto a biodegradable fibroin substrate for biosensing applications This study addresses a proof-of-concept experiment with a biocompatible screen-printed carbon electrode deposited onto a biocompatible and biodegradable substrate, which is made of fibroin, a protein derived from silk of the Bombyx mori silkworm. To demonstrate the sensor performance, the carbon electrode is functionalized as a glucose biosensor with the enzyme glucose oxidase and encapsulated with a silicone rubber to ensure biocompatibility of the contact wires. The carbon electrode is fabricated by means of thick-film technology including a curing step to solidify the carbon paste. The influence of the curing temperature and curing time on the electrode morphology is analyzed via scanning electron microscopy. The electrochemical characterization of the glucose biosensor is performed by amperometric/voltammetric measurements of different glucose concentrations in phosphate buffer. Herein, systematic studies at applied potentials from 500 to 1200 mV to the carbon working electrode (vs the Ag/AgCl reference electrode) allow to determine the optimal working potential. Additionally, the influence of the curing parameters on the glucose sensitivity is examined over a time period of up to 361 days. The sensor shows a negligible cross-sensitivity toward ascorbic acid, noradrenaline, and adrenaline. The developed biocompatible biosensor is highly promising for future in vivo and epidermal applications. Weinheim Wiley-VCH 2022 8 Physica status solidi (a) 219 Corresponding author: Michael J. Schöning 23 1 9 10.1002/pssa.202200100 weltweit https://doi.org/10.1002/pssa.202200100 Fachbereich Medizintechnik und Technomathematik OPUS4-4852 Wissenschaftlicher Artikel Kirchner, Patrick, kirchner@fh-aachen.de; Oberländer, Jan, oberlaender@fh-aachen.de; Friedrich, Peter, ; Berger, Jörg, ; Rysstad, Gunnar, ; Schöning, Michael Josef, schoening@fh-aachen.de; Keusgen, Michael, Realisation of a calorimetric gas sensor on polyimide foil for applications in aseptic food industry A calorimetric gas sensor is presented for the monitoring of vapour-phase H2O2 at elevated temperature during sterilisation processes in aseptic food industry. The sensor was built up on a flexible polyimide foil (thickness: 25 μm) that has been chosen due to its thermal stability and low thermal conductivity. The sensor set-up consists of two temperature-sensitive platinum thin-film resistances passivated by a layer of SU-8 photo resist and catalytically activated by manganese(IV) oxide. Instead of an active heating structure, the calorimetric sensor utilises the elevated temperature of the evaporated H2O2 aerosol. In an experimental test rig, the sensor has shown a sensitivity of 4.78 °C/(%, v/v) in a H2O2 concentration range of 0%, v/v to 8%, v/v. Furthermore, the sensor possesses the same, unchanged sensor signal even at varied medium temperatures between 210 °C and 270 °C of the gas stream. At flow rates of the gas stream from 8 m3/h to 12 m3/h, the sensor has shown only a slightly reduced sensitivity at a low flow rate of 8 m3/h. The sensor characterisation demonstrates the suitability of the calorimetric gas sensor for monitoring the efficiency of industrial sterilisation processes. Amsterdam Elsevier 2012 6 Sensors and Actuators B: Chemical 170 Part of special issue "Eurosensors XXIV, 2010" 60 66 10.1016/j.snb.2011.01.032 campus https://doi.org/10.1016/j.snb.2011.01.032 Fachbereich Medizintechnik und Technomathematik OPUS4-290 Konferenzveröffentlichung Schubert, Nicole, ; Schöning, Michael Josef, schoening@fh-aachen.de 3. Graduiertentagung der FH Aachen Doktoranden der FH Aachen stellen ihre wissenschaftlichen Arbeiten aus verschiedenen Fachdisziplinen vor. 2010 urn:nbn:de:hbz:a96-opus-3386 Fachbereich Elektrotechnik und Informationstechnik OPUS4-268 Konferenzveröffentlichung Schöning, Michael Josef, schoening@fh-aachen.de; Abdelghani, Adnane, Advancements in Nanotechnology and Microelectronics (ANM '09) <2009, Tunisia>: Proceedings book ; Tunisia, November, 13 & 14, 2009 / Humboldt Kolleg. Ed. by Michael J. Schöning ; Adnane Abdelghani The ANM'09 multi-disciplinary scientific program includes topics in the fields of "Nanotechnology and Microelectronics" ranging from "Bio/Micro/Nano Materials and Interfacing" aspects, "Chemical and Bio-Sensors", "Magnetic and Superconducting Devices", "MEMS and Microfluidics" over "Theoretical Aspects, Methods and Modelling" up to the important bridging "Academics meet Industry". 2009 urn:nbn:de:hbz:a96-opus-3113 Fachbereich Medizintechnik und Technomathematik OPUS4-269 Konferenzveröffentlichung Roderburg, Katharina, ; Schöning, Michael Josef, schoening@fh-aachen.de 1. Graduierten-Tagung : 9. September 2008 / [Hrsg.: K. Roderburg ; M. J. Schöning] Tagungsband der Graduiertentagung der FH Aachen, in dem Doktorandinnen und Doktoranden und ihre Forschungsbereiche vorgestellt werden 2008 urn:nbn:de:hbz:a96-opus-3125 FH Aachen OPUS4-270 Konferenzveröffentlichung Groebel, Simone, groebel@fh-aachen.de; Kowollik, Silvia, ; Crummenerl, Silvia, ; Schöning, Michael Josef, schoening@fh-aachen.de 2. Graduiertentagung : 5. November 2009 / [Hrsg.: S. Groebel ; S. Kowollik ; S. Crummenerl ; M. J. Schöning] Tagungsband der Graduiertentagung der FH Aachen, in dem Doktorandinnen und Doktoranden und ihre Forschungsbereiche vorgestellt werden 2009 urn:nbn:de:hbz:a96-opus-3131 FH Aachen OPUS4-305 Konferenzveröffentlichung Schusser, Sebastian, schusser@fh-aachen.de; Vaeßen, Christiane, vaessen@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de 4. Graduiertentagung der FH Aachen 24. November 2011 Tagungsband der 4. Graduiertentagung der FH Aachen am 24. November 2011 Proceedings from the 4th Graduate Symposium, FH Aachen, Germany, November 24th, 2011 Aachen, November 2011. 62 Seiten 2011 urn:nbn:de:hbz:a96-opus-3530 FH Aachen OPUS4-306 Konferenzveröffentlichung Schöning, Michael Josef, schoening@fh-aachen.de; Abdelghani, Adnane, Nanoscale Science and Technology (NS&T'12) : Proceedings Book Humboldt Kolleg <2012, Tunisia> ; Tunisia, 17-19 March, 2012 / ed. by Michael J. Schöning ; Adnane Abdelghani Proceedings of the 2nd Humboldt Kolleg, Hammamet, Tunisia Organizer: Alexander von Humboldt Stiftung, Germany. pdf 184 p. Welcome Address Dear Participants, Welcome to the 2nd Humboldt Kolleg in "Nanoscale Science and Technology" (NS&T'12) in Tunisia, sponsored by the "Alexander von Humboldt" foundation. The NS&T'12 multidisciplinary scientific program includes seven "hot" topics dealing with "Nanoscale Science and Technology" covering basic and application-oriented research as well as industrial (market) aspects: - Molecular Biophyics, Spectroscopy Techniques, Imaging Microscopy - Nanomaterials Synthesis for Medicine and Bio-chemical Sensors - Nanostructures, Semiconductors, Photonics and Nanodevices - New Technologies in Market Industry - Environment, Electro-chemistry, Bio-polymers and Fuel Cells - Nanomaterials, Photovoltaic, Modelling, Quantum Physics - Microelectronics, Sensors Networks and Embedded Systems We are deeply indebted to all members of the Scientific Committee and General Chairs for joint Sessions and to all speakers and chairmen, who have dedicated invaluable time and efforts for the realization of this event. On behalf of the Organizing Committee, we are cordially inviting you to join the conference and hope that your stay will be fruitful, rewarding and enjoyable. Prof. Dr. Michael J. Schöning, Prof. Dr. Adnane Abdelghani 2012 urn:nbn:de:hbz:a96-opus-3544 Fachbereich Medizintechnik und Technomathematik OPUS4-357 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Schubert, J, ; Kloock, Joachim P., kloock@fh-aachen.de; Zander, W., ; Mourzina, Y. G., ; Legin, A., ; Vlasov, Y. G., ; Lüth, H., Innovative thin film techniques for microfabricating electrochemical sensors Warsaw MCB 2002 11 Lecture Notes of the ICB Seminars 55 66 Fachbereich Medizintechnik und Technomathematik OPUS4-358 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de Silicon-based biochemical sensors Foschungszentrum Jülich 2003 5 CNI - The Center of Nanoelectronic Systems for Information Technology 165 170 Fachbereich Medizintechnik und Technomathematik OPUS4-359 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Lüth, H., Microfabricated semiconductor structures - Advances in (bio-)chemical sensing Berlin [u.a.] Springer 2002 126 S. : graph. Darst Coupling of biological and electronic systems : proceedings of the 2nd Caesarium, Bonn, November 1 - 3, 2000 / Karl-Heinz Hoffmann, ed. 3-540-43699-5 79 92 Fachbereich Medizintechnik und Technomathematik OPUS4-360 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Schubert, Joachim P., ; Kloock, Joachim P., kloock@fh-aachen.de; Zander, W., ; Mourzina, Y. G., ; Legin, A., ; Vlasov, Y. G., ; Lüth, H., Innovative thin film techniques for microfabricating electrochemical sensors 2001 12 Biocybernetics and Biomedical Engineering. 21 (2001), H. 4 0208-5216 107 119 Fachbereich Medizintechnik und Technomathematik OPUS4-361 Wissenschaftlicher Artikel Schroth, P., ; Weißbecker, B., ; Schütz, S., ; Ecken, H., ; Yoshinobu, T., ; Lüth, H., ; Schöning, Michael Josef, schoening@fh-aachen.de Bioelectronic signal processing - intact chemoreceptors coupled to field-effect devices Warsaw MCB 2002 14 Lecture Notes of the ICB Seminars 28 42 Fachbereich Medizintechnik und Technomathematik OPUS4-362 Wissenschaftlicher Artikel Schroth, P., ; Weißbecker, B., ; Schütz, S., ; Ecken, H., ; Yoshinobu, T., ; Lüth, H., ; Schöning, Michael Josef, schoening@fh-aachen.de Bioelectronic signal processing - intact chemoreceptors coupled to field-effect devices 2001 15 Biocybernetics and Biomedical Engineering. 21 (2001), H. 3 0208-5216 27 42 Fachbereich Medizintechnik und Technomathematik OPUS4-363 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de Novel approaches to design siliconbased field-effect sensors London New York Taylor & Francis 2002 24 Electrochemical Microsystem Technologies, New Trends in Electrochemistry Vol. 2 384 408 Fachbereich Medizintechnik und Technomathematik OPUS4-364 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Lüth, H., Novel concepts for silicon-based biosensors 2001 12 Physica Status Solidi (A) (2001) 0031-8965 65 77 campus http://www3.interscience.wiley.com/cgi-bin/fulltext/82002062/PDFSTART Fachbereich Medizintechnik und Technomathematik OPUS4-5150 Wissenschaftlicher Artikel Reisert, Steffen, reisert@fh-aachen.de; Schneider, Benno, benno.schneider@fh-aachen.de; Geissler, Hanno, ; Gompel, Matthias van, ; Wagner, Patrick, ; Schöning, Michael Josef, schoening@fh-aachen.de Multi-sensor chip for the investigation of different types of metal oxides for the detection of H2O2 in the ppm range In this work, a multi-sensor chip for the investigation of the sensing properties of different types of metal oxides towards hydrogen peroxide in the ppm range is presented. The fabrication process and physical characterization of the multi-sensor chip are described. Pure SnO2 and WO3 as well as Pd- and Pt-doped SnO2 films are characterized in terms of their sensitivity to H2O2. The sensing films have been prepared by drop-coating of water-dispensed nano-powders. A physical characterization, including scanning electron microscopy and X-ray diffraction analysis of the deposited metal-oxide films, was done. From the measurements in hydrogen peroxide atmosphere, it could be shown, that all of the tested metal oxide films are suitable for the detection of H2O2 in the ppm range. The highest sensitivity and reproducibility was achieved using Pt-doped SnO2. Calibration plot of a SnO2, WO3, Pt-, and Pd-doped SnO2 gas sensor for H2O2 concentrations in the ppm range. Weinheim Wiley 2013 6 physica status solidi (a) Vol. 210 Iss. 5 898 904 campus http://dx.doi.org/10.1002/pssa.201200930 Fachbereich Medizintechnik und Technomathematik OPUS4-1550 Wissenschaftlicher Artikel Wagner, Torsten, torsten.wagner@fh-aachen.de; Beging, Stefan, beging@fh-aachen.de; Rotter, L., ; Poghossian, Arshak, poghossian@fh-aachen.de; Biselli, Manfred, biselli@fh-aachen.de; Zang, Werner, zang@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de Online-Messsysteme für die automatisierte Charakterisierung von feldeffektbasierten Biosensoren Dresden TUDpress, Verl. der Wissenschaften 2007 343 S. : Ill., graph. Darst. 8. Dresdner Sensor-Symposium : Sensoren für Umwelt, Klima und Sicherheit, Biosensoren und Biosysteme, Sensoren und Sensorsysteme für die Prozesstechnik, Trends in der Sensortechnik, Materialentwicklung für die Sensorik; 8. Dresdner Sensor-Symposium, 10. - 12. Dezember 2007, Dresden / Gerald Gerlach ... (Hg.) 978-3-940046-45-1 Dresdner Sensor-Symposium <8, 2007, Dresden> ; Dresdner Beiträge zur Sensorik ; 29 257 260 Fachbereich Chemie und Biotechnologie OPUS4-1720 Wissenschaftlicher Artikel Poghossian, Arshak, poghossian@fh-aachen.de; Platen, J., ; Schöning, Michael Josef, schoening@fh-aachen.de Towards self-aligned nanostructures by means of layerexpansion technique 2005 5 Electrochimica Acta. 51 (2005), H. 5 0013-4686 838 843 campus http://dx.doi.org/10.1016/j.electacta.2005.04.065 Fachbereich Medizintechnik und Technomathematik OPUS4-1721 Wissenschaftlicher Artikel Näther, Niko, naether@fh-aachen.de; Rolka, David, d.rolka@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de; Koudelka-Hep, M., ; Schöning, Michael Josef, schoening@fh-aachen.de Two microcell flow-injection analysis (FIA) platforms for capacitive silicon-based field-effect sensors 2005 5 Electrochimica Acta. 51 (2005), H. 5 0013-4686 924 929 10.1016/j.electacta.2005.04.066 campus Fachbereich Medizintechnik und Technomathematik OPUS4-1722 Wissenschaftlicher Artikel Simonis, A., ; Dawgul, M., ; Lüth, H., ; Schöning, Michael Josef, schoening@fh-aachen.de Miniaturised reference electrodes for field-effect sensors compatible to silicon chip technology 2005 7 Electrochimica Acta. 51 (2005), H. 5 0013-4686 930 937 10.1016/j.electacta.2005.04.063 campus Fachbereich Medizintechnik und Technomathematik OPUS4-1723 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Näther, Niko, naether@fh-aachen.de; Auger, V., ; Poghossian, Arshak, poghossian@fh-aachen.de; Koudelka-Hep, M., Miniaturised flow-through cell with integrated capacitive EIS sensor fabricated at wafer level using Si and SU-8 technologies 2005 6 Sensors and Actuators B. 108 (2005), H. 1-2 0925-4005 Proceedings of the Tenth International Meeting on Chemical Sensors — IMCS - 10 2004 986 992 campus http://dx.doi.org/10.1016/j.snb.2004.12.029 Fachbereich Medizintechnik und Technomathematik OPUS4-1724 Wissenschaftlicher Artikel Poghossian, Arshak, poghossian@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de Detecting Both Physical and (Bio-)Chemical Parameters by Means of ISFET Devices 2004 9 Electroanalysis. 16 (2004), H. 22 1040-0397 1863 1872 campus http://dx.doi.org/10.1002/elan.200403074 Fachbereich Medizintechnik und Technomathematik OPUS4-1685 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de Recent advances in biologically sensitive field-effect transistors (BioFETs) 2002 14 Analyst. 127 (2002) 0003-2654 1137 1151 weltweit http://dx.doi.org/10.1039/B204444G Fachbereich Medizintechnik und Technomathematik OPUS4-1687 Wissenschaftlicher Artikel Poghossian, Arshak, poghossian@fh-aachen.de; Lüth, H., ; Schultze, J. W., ; Schöning, Michael Josef, schoening@fh-aachen.de (Bio-)chemical and physical microsensor array using an identical transducer principle Amsterdam [u.a.] Elsevier [u.a.] 2001 385 S. : Ill., graph. Darst. Scaling down in electrochemistry : electrochemical micro- and nanosystem technology ; proceedings of the 3rd International Symposium on Electrochemical Microsystem Technologies, Garmisch-Patenkirchen, Germany, 11 - 15 September 2000 / ed. by J. W. Schultz 0-08-044014-2 243 249 Fachbereich Medizintechnik und Technomathematik OPUS4-1688 Wissenschaftlicher Artikel Yoshinobu, T., ; Ecken, H., ; Ismail, Md.A.B., ; Iwasaki, H., ; Lüth, H., ; Schöning, Michael Josef, schoening@fh-aachen.de Chemical imaging sensor and its application to biological systems Amsterdam [u.a.] Elsevier [u.a.] 2001 385 S. : Ill., graph. Darst. Scaling down in electrochemistry : electrochemical micro- and nanosystem technology ; proceedings of the 3rd International Symposium on Electrochemical Microsystem Technologies, Garmisch-Patenkirchen, Germany, 11 - 15 September 2000 / ed. by J. W. Schultz 0-08-044014-2 259 263 Fachbereich Medizintechnik und Technomathematik OPUS4-1689 Wissenschaftlicher Artikel Schroth, P., ; Lüth, H., ; Hummel, Hans E., ; Schütz, S., ; Schöning, Michael Josef, schoening@fh-aachen.de Characterising an insect antenna as a receptor for a biosensor by means of impedance spectroscopy Amsterdam [u.a.] Elsevier [u.a.] 2001 385 S. : Ill., graph. Darst. Scaling down in electrochemistry : electrochemical micro- and nanosystem technology ; proceedings of the 3rd International Symposium on Electrochemical Microsystem Technologies, Garmisch-Patenkirchen, Germany, 11 - 15 September 2000 / ed. by J. W. Schultz 0-08-044014-2 293 297 Fachbereich Medizintechnik und Technomathematik OPUS4-1690 Wissenschaftlicher Artikel Heiduschka, P., ; Romann, I., ; Ecken, H., ; Schöning, Michael Josef, schoening@fh-aachen.de; Schuhmann, W., ; Thanos, S., Defined adhesion and growth of neurones on artificial structured substrates Amsterdam [u.a.] Elsevier [u.a.] 2001 385 S. : Ill., graph. Darst. Scaling down in electrochemistry : electrochemical micro- and nanosystem technology ; proceedings of the 3rd International Symposium on Electrochemical Microsystem Technologies, Garmisch-Patenkirchen, Germany, 11 - 15 September 2000 / ed. by J. W. Schultz 0-08-044014-2 299 307 Fachbereich Medizintechnik und Technomathematik OPUS4-1694 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de Feldeffektstrukturen mit AgI-Aufdampfschichten als chemische Sensoren 1993 94 KfK-Bericht. 5195 (1993) 0303-4003 1 95 Fachbereich Medizintechnik und Technomathematik OPUS4-1746 Wissenschaftlicher Artikel Poghossian, Arshak, poghossian@fh-aachen.de; Mai, D.-T., ; Mourzina, Y., ; Schöning, Michael Josef, schoening@fh-aachen.de Impedance effect of an ion-sensitive membrane: characterisation of an EMIS sensor by impedance spectroscopy, capacitance-voltage and constant-capacitance method 2004 5 Sensors and Actuators B. 103 (2004), H. 1-2 0925-4005 423 428 campus http://dx.doi.org/10.1016/j.snb.2004.04.071 Fachbereich Medizintechnik und Technomathematik OPUS4-1749 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Kloock, Joachim P., kloock@fh-aachen.de Labor für Chemo- und Biosensorik an der FH Aachen, Abt. Jülich - Mehr als nur studieren 2004 1 Fachblatt Fachhochschule Aachen (2004) 1430-7707 18 19 weltweit http://www.fh-aachen.de/fileadmin/groups/pressestelle/fachblatt/Fachblatt2_2004.pdf Fachbereich Medizintechnik und Technomathematik OPUS4-1750 Wissenschaftlicher Artikel Kloock, Joachim P., kloock@fh-aachen.de; Mourzina, Y.G., ; Ermolenko, Y., ; Doll, T., ; Schubert, J., ; Schöning, Michael Josef, schoening@fh-aachen.de Inorganic thin-film sensor membranes with PLD-prepared chalcogenide glasses: Challenges and implementation 2004 6 Sensors. 4 (2004), H. 10 1424-8220 156 162 weltweit http://www.mdpi.org/sensors/papers/s41000156.pdf Fachbereich Medizintechnik und Technomathematik OPUS4-1751 Wissenschaftlicher Artikel Yoshinobu, T., ; Schöning, Michael Josef, schoening@fh-aachen.de; Finger, F., ; Moritz, W., ; Iwasaki, H., Fabrication of thin-film LAPS with amorphous silicon 2004 6 Sensors. 4 (2004), H. 10 1424-8220 163 169 weltweit http://www.mdpi.org/sensors/papers/s41000163.pdf Fachbereich Medizintechnik und Technomathematik OPUS4-1752 Wissenschaftlicher Artikel Poghossian, Arshak, poghossian@fh-aachen.de; Ingebrandt, S., ; Yeung, C.-K., ; Offenhäusser, A., ; Schöning, Michael Josef, schoening@fh-aachen.de Microsensors based on ion-sensitive field-effect transistors for biomedical applications 2004 1 Biomedizinische Technik. 49 (2004), H. 2 0932-4666 1036 1037 Fachbereich Medizintechnik und Technomathematik OPUS4-1753 Wissenschaftlicher Artikel Kassab, T., ; Han, Y., ; Poghossian, Arshak, poghossian@fh-aachen.de; Ingebrandt, S., ; Offenhäusser, A., ; Schöning, Michael Josef, schoening@fh-aachen.de Detection of layerby-layer adsorbed polyelectrolytes by means of field-effect based capacitive EIS structures 2004 1 Biomedizinische Technik. 49 (2004), H. 2 0932-4666 1034 1035 Fachbereich Medizintechnik und Technomathematik OPUS4-1754 Wissenschaftlicher Artikel Moritz, W., ; Yoshinobu, T., ; Finger, F., ; Krause, S., ; Xu, M., ; Schöning, Michael Josef, schoening@fh-aachen.de Microscopy of impedance and surface ion concentrations 2004 1 Biomedizinische Technik. 49 (2004), H. 2 0932-4666 1000 1001 Fachbereich Medizintechnik und Technomathematik OPUS4-1709 Wissenschaftlicher Artikel Ermolenko, Y. E., ; Yoshinobu, T., ; Mourzina, Y. G., ; Vlasov, Y. G., ; Schöning, Michael Josef, schoening@fh-aachen.de; Iwasaki, H., Laserscanned transducer (LSST) as a multisensor system 2004 5 Sensors and Actuators B. 103 (2004), H. 1-2 0925-4005 457 462 campus http://dx.doi.org/10.1016/j.snb.2004.05.005 Fachbereich Medizintechnik und Technomathematik OPUS4-1710 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Glück, O., ; Thust, M., Electrochemical methods for the determination of chemical variables in aqueous media Boca Raton [u.a.] CRC Press 1999 2506 S. in getr. Zählung : Ill., graph. Darst., 26 The measurement, instrumentation, and sensors handbook / ed.-in-chief John G. Webster. In cooperation with IEEE Press 0-8493-8347-1 1 49 Fachbereich Medizintechnik und Technomathematik OPUS4-1711 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Thust, M., ; Kordos, P., ; Lüth, H., Chemical sensing structures - From EIS capacitors to array-type sensors Faenza Techna 1999 XVI, 546 S. : Ill., graph. Darst. Solid state chemical and biochemical sensors : proceedings of Topical Symposium 9 - "Solid State Chemical and Biochemical Sensors" of the Forum on New Materials of the 9th CIMTEC-World Ceramics Congress and Forum on New Materials Florence, Italy June 14-1 88-86538-27-8 Serie Advances in science and technology ; 26 55 62 Fachbereich Medizintechnik und Technomathematik OPUS4-1713 Wissenschaftlicher Artikel Schütz, S., ; Weißbecker, G., ; Schroth, P., ; Schöning, Michael Josef, schoening@fh-aachen.de Linkage of inanimate structures to biological systems - smart materials in biological micro- nanosystems Berlin [u.a.] Springer 2001 VIII, 165 S. : zahlr. Ill. und graph. Darst. Smart materials : proceedings of the 1st Caesarium, Bonn, November 17 - 19, 1999 / Karl-Heinz Hoffmann ed. 3-540-67957-X 149 157 Fachbereich Medizintechnik und Technomathematik OPUS4-1714 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Schroth, P., ; Schütz, S., The use of insect chemoreceptors for the assembly of biosensors based on semiconductor field-effect sensors 2000 7 Electroanalysis. 12 (2000), H. 9 1040-0397 645 652 campus http://www3.interscience.wiley.com/cgi-bin/fulltext/72507591/PDFSTART Fachbereich Medizintechnik und Technomathematik OPUS4-1755 Wissenschaftlicher Artikel Yoshinobu, T., ; Ui, Y., ; Iwasaki, H., ; Näther, Niko, naether@fh-aachen.de; Koudelka-Hep, M., ; Schöning, Michael Josef, schoening@fh-aachen.de Potentiometric imaging in a microfluidic channel 2004 1 Biomedizinische Technik. 49 (2004), H. 2 0932-4666 998 999 Fachbereich Medizintechnik und Technomathematik OPUS4-1756 Wissenschaftlicher Artikel Wagner, Torsten, torsten.wagner@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de; Otto, R., ; Yoshinobu, T., A handheld 16 channel pen-type LAPS as a platform for (bio-)electrochemical sensing 2004 1 Biomedizinische Technik. 49 (2004), H. 2 0932-4666 996 997 Fachbereich Medizintechnik und Technomathematik OPUS4-1757 Wissenschaftlicher Artikel Näther, Niko, naether@fh-aachen.de; Auger, V., ; Poghossian, Arshak, poghossian@fh-aachen.de; Koudelka-Hep, M., ; Schöning, Michael Josef, schoening@fh-aachen.de A miniaturized flow-through cell in SU-8 technique for EIS sensors 2004 1 Biomedizinische Technik. 49 (2004), H. 2 0932-4666 994 995 Fachbereich Medizintechnik und Technomathematik OPUS4-1758 Wissenschaftlicher Artikel Rolka, David, d.rolka@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de Integration of a capacitive EIS sensor into a FIA system for pH and penicillin determination 2004 10 Sensors. 4 (2004) 1424-8220 84 94 weltweit http://www.mdpi.org/sensors/papers/s40670084.pdf Fachbereich Medizintechnik und Technomathematik OPUS4-1759 Wissenschaftlicher Artikel Muck, A., ; Wang, J., ; Jacobs, M., ; Chen, G., ; Chatrathi, M. P., ; Jurka, V., ; Vyborny, Z., ; Spillmann, S. D., ; Sridharan, G., ; Schöning, Michael Josef, schoening@fh-aachen.de Fabrication of poly(methyl methacrylate) microfluidic chips by atmospheric molding 2004 7 Analytical Chemistry. 76 (2004), H. 8 0003-2700 2290 2297 campus http://dx.doi.org/10.1021/ac035030+ Fachbereich Medizintechnik und Technomathematik OPUS4-1760 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Kloock, Joachim P., kloock@fh-aachen.de; Knobbe, D.-T., ; Krause, R., ; Block, K., ; Wang, J., ; Mulchandani, A., ; Keusgen, M., Direktnachweis von Pestiziden und Cyanid mit elektrochemischen Enzymsensoren Düsseldorf VDI 2004 922 S. : Ill., graph. Darst. Sensoren und Messsysteme 2004 : Tagung Ludwigsburg, 15. und 16. März 2004 / VDI-VDE-Gesellschaft Mess- und Automatisierungstechnik 3-18-091829-2 Auch erschienen als: VDI-Berichte ; 1829 699 706 Fachbereich Medizintechnik und Technomathematik OPUS4-1761 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Jünger, M., ; Keusgen, M., Knoblauchgehaltsbestimmungen mit einem feldeffektbasierten Halbleiterbiosensor Düsseldorf VDI 2004 922 S. : Ill., graph. Darst Sensoren und Messsysteme 2004 : Tagung Ludwigsburg, 15. und 16. März 2004 / VDI-VDE-Gesellschaft Mess- und Automatisierungstechnik 3-18-091829-2 Auch erschienen als: VDI-Berichte ; 1829 707 714 Fachbereich Medizintechnik und Technomathematik OPUS4-1762 Wissenschaftlicher Artikel Simonis, A., ; Lüth, H., ; Wang, J., ; Schöning, Michael Josef, schoening@fh-aachen.de Miniaturisierte Referenzelektroden in Siliziumtechnologie für elektrochemische Sensoranwendungen Düsseldorf VDI 2004 922 S. : Ill., graph. Darst Sensoren und Messsysteme 2004 : Tagung Ludwigsburg, 15. und 16. März 2004 / VDI-VDE-Gesellschaft Mess- und Automatisierungstechnik 3-18-091829-2 Auch erschienen als: VDI-Berichte ; 1829 847 850 Fachbereich Medizintechnik und Technomathematik OPUS4-1763 Wissenschaftlicher Artikel Knobbe, D.-T., ; Schöning, Michael Josef, schoening@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de; Mourzina, Y., Charakterisierung von kapazitiven EMISSensoren mittels Impedanzspektroskopie, Kapazitäts-Spannungs- und Konstant-Kapazitäts-Messung Düsseldorf VDI 2004 922 S. : Ill., graph. Darst Sensoren und Messsysteme 2004 : Tagung Ludwigsburg, 15. und 16. März 2004 / VDI-VDE-Gesellschaft Mess- und Automatisierungstechnik 3-18-091829-2 Auch erschienen als: VDI-Berichte ; 1829 851 854 Fachbereich Medizintechnik und Technomathematik OPUS4-1764 Wissenschaftlicher Artikel Mourzina, Ioulia G., ; Yoshinobu, Tatsuo, ; Ermolenko, Yuri E., ; Vlasov, Yuri G., ; Schöning, Michael Josef, schoening@fh-aachen.de; Iwasaki, H., Immobilization of urease and cholinesterase on the surface of semiconductor transducer for the development of lightaddressable potentiometric sensors 2004 9 Microchimica Acta. 144 (2004), H. 1-3 0026-3672 41 50 campus http://dx.doi/org/10.1007/s00604-003-0091-4 Fachbereich Medizintechnik und Technomathematik OPUS4-1696 Wissenschaftlicher Artikel Moritz, W., ; Yoshinobu, T., ; Finger, F., ; Krause, S., ; Martin-Fernandez, M., ; Schöning, Michael Josef, schoening@fh-aachen.de High resolution LAPS using amorphous silicon as the semiconductor material 2004 8 Sensors and Actuators B. 103 (2004), H. 1-2 0925-4005 436 444 campus http://dx.doi.org/10.1016/j.snb.2004.04.073 Fachbereich Medizintechnik und Technomathematik OPUS4-1697 Wissenschaftlicher Artikel Glück, O., ; Schöning, Michael Josef, schoening@fh-aachen.de; Lüth, H., ; Emons, H., ; Otto, A., Schwermetallbestimmung mittels Widerstandsmessungen und Voltammetrie an Dünnschichtelektroden Dresden ; München Dresden Univ. Press 1998 VII, 244 S. : Ill., graph. Darst. Chemie- und Biosensoren : aktuelle Anwendungen und Entwicklungstrends / 3. Dresdner Sensor-Symposium, 8. - 10. Dezember 1997, Dresden-Radebeul. J. P. Baselt ... (Hg.) 3-933168-03-1 Serie Dresdner Beiträge zur Sensorik ; 5 165 168 Fachbereich Medizintechnik und Technomathematik OPUS4-1698 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Prämassing, T., ; Beckers, L., ; Zander, W., Ein langzeitstabiler pH-Sensor auf Siliziumbasis hergestellt in Dünnschichttechnik mittels Laserablation Dresden ; München Dresden Univ. Press 1998 VII, 244 S. : Ill., graph. Darst Chemie- und Biosensoren : aktuelle Anwendungen und Entwicklungstrends / 3. Dresdner Sensor-Symposium, 8. - 10. Dezember 1997, Dresden-Radebeul. J. P. Baselt ... (Hg.) 3-933168-03-1 Serie Dresdner Beiträge zur Sensorik ; 5 99 102 Fachbereich Medizintechnik und Technomathematik OPUS4-1700 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Glück, O., ; Schroth, P., ; Schütz, S. (u.a.), Microelectrodes, capacitors and BioFETs: Novel trends in silicon-based biochemical sensing 1999 21 Biocybernetics and Biomedical Engineering. 19 (1999), H. 1 105 126 Fachbereich Medizintechnik und Technomathematik OPUS4-1703 Wissenschaftlicher Artikel Keusgen, M., ; Kloock, Joachim P., kloock@fh-aachen.de; Knobbe, D.-T., ; Jünger, M., ; Krest, I., ; Goldbach, M., ; Klein, W., ; Schöning, Michael Josef, schoening@fh-aachen.de Direct determination of cyanides by potentiometric biosensors 2004 5 Sensors and Actuators B. 103 (2004), H. 1-2 0925-4005 380 385 bezahl http://dx.doi.org/10.1016/j.snb.2004.04.067 Fachbereich Medizintechnik und Technomathematik OPUS4-1725 Wissenschaftlicher Artikel Poghossian, Arshak, poghossian@fh-aachen.de; Cherstvy, A., ; Ingebrandt, S., ; Offenhäusser, A., ; Schöning, Michael Josef, schoening@fh-aachen.de Possibilities and limitations of label-free detection of DNA hybridization with field-effect-based devices 2005 10 Sensors and Actuators B. 111-112 (2005) 0925-4005 Eurosensors XVIII 2004 — The 18th European Conference on Solid-State Transducers 470 480 campus http://dx.doi.org/10.1016/j.snb.2005.03.083 Fachbereich Medizintechnik und Technomathematik OPUS4-1726 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Jacobs, M., ; Muck, A., ; Knobbe, D.-T., ; Wang, J., ; Chatrathi, M., ; Spillmann, S., Amperometric PDMS/glass capillary electrophoresis-based biosensor microchip for catechol and dopamin detection 2005 6 Sensors and Actuators B. 108 (2005), H. 1-2 0925-4005 Proceedings of the Tenth International Meeting on Chemical Sensors — IMCS - 10 2004 688 694 campus http://dx.doi.org/10.1016/j.snb.2004.11.032 Fachbereich Medizintechnik und Technomathematik OPUS4-1727 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Wagner, Torsten, torsten.wagner@fh-aachen.de; Wang, C., ; Otto, R., ; Yoshinobu, T., Development of a handheld 16 channel pen-type LAPS for electrochemical sensing 2005 6 Sensors and Actuators B. 108 (2005) 0925-4005 808 814 campus http://dx.doi.org/10.1016/j.snb.2005.01.055 Fachbereich Medizintechnik und Technomathematik OPUS4-1728 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de "Playing around" with field-effect sensors on the basis of EIS structures, LAPS and ISFETs 2005 12 Sensors. 5 (2005), H. 3 1424-8220 126 138 weltweit http://www.mdpi.net/sensors/papers/s5030126.pdf Fachbereich Medizintechnik und Technomathematik OPUS4-1729 Wissenschaftlicher Artikel Simonis, A., ; Lüth, H., ; Wang, J., ; Schöning, Michael Josef, schoening@fh-aachen.de New concepts of miniaturised reference electrodes in silicon technology for potentiometric sensor systems 2004 6 Sensors and Actuators B. 103 (2004), H. 1-2 0925-4005 429 435 campus http://dx.doi.org/10.1016/j.snb.2004.04.072 Fachbereich Medizintechnik und Technomathematik OPUS4-1681 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de "Voltohmmetry" - a new transducer principle for electrochemical sensors Berlin [u.a.] Springer 2004 XX, 358 S. : graph. Darst., 24 cm Ultrathin electrochemical chemo- and biosensors : technology and performance / Vladimir M. Mirsky 3-540-21285-X 117 140 Fachbereich Medizintechnik und Technomathematik OPUS4-1682 Wissenschaftlicher Artikel Keusgen, M., ; Jünger, M., ; Knobbe, D.-T., ; Kloock, Joachim P., kloock@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de Entwicklung eines potentiometrischen Cyanid-Biosensors auf der Basis von EIS-Strukturen Dresden w.e.b.-Univ.-Verl. 2003 343 S : Ill., graph. Darst ; 23 cm. Sensoren für zukünftige Hochtechnologien und Neuentwicklungen für die Verfahrenstechnik / 6. Dresdner Sensor-Symposium, 8. - 10. Dezember 2003, Dresden. Jörg Peter Baselt; Gerald Gerlach (Hg.) 3-935712-92-8 235 238 Fachbereich Medizintechnik und Technomathematik OPUS4-1683 Wissenschaftlicher Artikel Thust, M., ; Schöning, Michael Josef, schoening@fh-aachen.de; Muchandani, A., ; Wang, J., ; Arzdorf, M., ; Mulchandani, P., ; Chen, W., Feldeffekt-Enzymsensor zur Detektion von Pestiziden Dresden w.e.b.-Univ.-Verl. 2003 343 S : Ill., graph. Darst ; 23 cm Sensoren für zukünftige Hochtechnologien und Neuentwicklungen für die Verfahrenstechnik / 6. Dresdner Sensor-Symposium, 8. - 10. Dezember 2003, Dresden. Jörg Peter Baselt; Gerald Gerlach (Hg.) 3-935712-92-8 125 128 Fachbereich Medizintechnik und Technomathematik OPUS4-1684 Wissenschaftlicher Artikel Poghossian, Arshak, poghossian@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de "High-order" hybrid FET module for (bio)chemical and physical sensing Amsterdam [u.a.] Elsevier 2003 XXV, 709 S. : Ill., graph. Darst Integrated analytical systems / ed. by Salvador Alegret 0-444-51037-0 587 623 Fachbereich Medizintechnik und Technomathematik OPUS4-1740 Wissenschaftlicher Artikel Keusgen, M., ; Schöning, Michael Josef, schoening@fh-aachen.de Strategies for biosensoric detection of potential drugs in nature 2004 1 Biomedizinische Technik. 49 (2004), H. 2 0932-4666 1004 1005 Fachbereich Medizintechnik und Technomathematik OPUS4-1741 Wissenschaftlicher Artikel Kloock, Joachim P., kloock@fh-aachen.de; Mourzina, Y., ; Schubert, J., ; Ermelenko, Y., ; Schöning, Michael Josef, schoening@fh-aachen.de Pulsed laser deposition: A tool for fabricating thin-film microsensors 2004 1 Biomedizinische Technik. 49 (2004), H. 2 0932-4666 1032 1033 Fachbereich Medizintechnik und Technomathematik OPUS4-1826 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Kurowski, A., ; Thust, M., ; Kordos, P., ; Schultze, J. W., ; Lüth, H., Capacitive microsensors for biochemical sensing on porous silicon technology 2000 5 Sensors and Actuators B. 64 (2000), H. 1-3 0925-4005 59 64 campus http://dx.doi.org/10.1016/S0925-4005(99)00484-0 Fachbereich Medizintechnik und Technomathematik OPUS4-1827 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Schütz, S., ; Schroth, P., ; Weißbecker, B., ; Steffen, A., ; Kordos, P., ; Hummel, Hans E., A BioFET on the basis of intact insect antennae 1998 3 Sensors and Actuators B. 47 (1998), H. 1-3 0925-4005 235 238 campus http://dx.doi.org/10.1016/S0925-4005(98)00029-X Fachbereich Medizintechnik und Technomathematik OPUS4-1828 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Thust, M., ; Müller-Veggian, Mattea, mueller-veggian@opus.fh-aachen.de; Kordos, P., A novel silicon-based sensor array with capacitive EIS structures 1998 5 Sensors and Actuators B. 47 (1998), H. 1-3 0925-4005 225 230 campus http://dx.doi.org/10.1016/S0925-4005(98)00027-6 Fachbereich Medizintechnik und Technomathematik OPUS4-1829 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Tsarouchas, D., ; Schaub, A., ; Beckers, L. (u.a.), A highly long-term stable silicon-based pH sensor using pulsed laser deposition technique 1996 5 Sensors and Actuators B. 35 (1996), H. 1-3 0925-4005 228 233 bezahl http://dx.doi.org/10.1016/S0925-4005(97)80060-3 Fachbereich Medizintechnik und Technomathematik OPUS4-1830 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Sauke, M., ; Steffen, A., ; Marso, M. (u.a.), Ion-sensitive field-effect transistors with ultrathin Langmuir-Blodgett membranes 1995 3 Sensors and Actuators B. 27 (1995), H. 1-3 0925-4005 325 328 bezahl http://dx.doi.org/10.1016/0925-4005(94)01611-K Fachbereich Medizintechnik und Technomathematik OPUS4-1831 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Bruns, M., ; Hoffmann, W., ; Hoffmann, B. (u.a.), Iodide ion-sensitive field-effect structures 1993 2 Sensors and Actuators B. 15 (1993), H. 1-3 0925-4005 192 194 bezahl http://dx.doi.org/10.1016/0925-4005(93)85049-G Fachbereich Medizintechnik und Technomathematik OPUS4-1832 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Simonis, Anette, ; Ruge, Christian, ; Ecken, Holger, ; Müller-Veggian, Mattea, mueller-veggian@opus.fh-aachen.de; Lüth, Hans, A (bio-)chemical Field-effect Sensor with Macroporous Si as Substrate Material and a SiO₂ / LPCVD-Si₃N₄ Double Layer as pH Transducer Macroporous silicon has been etched from n-type Si, using a vertical etching cell where no rear side contact on the silicon wafer is necessary. The resulting macropores have been characterised by means of Scanning Electron Microscopy (SEM). After etching, SiO₂ was thermally grown on the top of the porous silicon as an insulating layer and Si₃N₄ was deposited by means of Low Pressure Chemical Vapour Deposition (LPCVD) as transducer material to fabricate a capacitive pH sensor. In order to prepare porous biosensors, the enzyme penicillinase has been additionally immobilised inside the porous structure. Electrochemical measurements of the pH sensor and the biosensor with an Electrolyte/Insulator/Semiconductor (EIS) structure have been performed in the Capacitance/Voltage (C/V) and Constant capacitance (ConCap) mode. 2002 11 Sensors. 2 (2002), H. 1 1424-8220 11 22 10.3390/s20100011 weltweit https://doi.org/10.3390/s20100011 Fachbereich Medizintechnik und Technomathematik OPUS4-1833 Wissenschaftlicher Artikel Simonis, A., ; Krings, T., ; Lüth, H., ; Wang, J., ; Schöning, Michael Josef, schoening@fh-aachen.de A „hybrid" thin-film pH sensor with integrated thick-film reference 2001 9 Sensors. 1 (2001), H. 6 1424-8220 183 192 weltweit http://www.mdpi.net/sensors/papers/s10600183.pdf Fachbereich Medizintechnik und Technomathematik OPUS4-1834 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de Microelectronics contacts (bio-)chemistry - Semiconductor-based sensors 2001 5 Biologi Italiani. 8 (2001) 0392-2510 5 10 Fachbereich Medizintechnik und Technomathematik OPUS4-1785 Wissenschaftlicher Artikel Mourzina, Y. G., ; Ermelenko, Y. E., ; Yoshinobu, T., ; Vlasov, Y., ; Iwasaki, H., ; Schöning, Michael Josef, schoening@fh-aachen.de Anionselective light-addressable potentiometric sensors (LAPS) for the determination of nitrate and suphate ions 2003 6 Sensors and Actuators B. 91 (2003), H. 1-3 0925-4005 32 38 campus http://dx.doi.org/10.1016/S0925-4005(03)00063-7 Fachbereich Medizintechnik und Technomathematik OPUS4-1786 Wissenschaftlicher Artikel Simonis, A., ; Ruge, C., ; Müller-Veggian, Mattea, mueller-veggian@opus.fh-aachen.de; Lüth, H., ; Schöning, Michael Josef, schoening@fh-aachen.de A long-term stable macroporoustype EIS structure for electrochemical sensor applications 2003 4 Sensors and Actuators B. 91 (2003), H. 1-3 0925-4005 21 25 campus http://dx.doi.org/10.1016/S0925-4005(03)00061-3 Fachbereich Medizintechnik und Technomathematik OPUS4-1787 Wissenschaftlicher Artikel Keusgen, M., ; Jünger, M., ; Krest, I., ; Schöning, Michael Josef, schoening@fh-aachen.de Development of a biosensor specific for cysteine sulfoxides 2003 7 Biosensors & Bioelectronics. 18 (2003), H. 5-6 0956-5663 805 812 campus http://dx.doi.org/10.1016/S0956-5663(03)00045-9 Fachbereich Medizintechnik und Technomathematik OPUS4-1788 Wissenschaftlicher Artikel Ermelenko, Y., ; Yoshinobu, T., ; Mourzina, Y., ; Schöning, Michael Josef, schoening@fh-aachen.de; Furuichi, K., ; Levichev, S., ; Vlasov, Y., ; Iwasaki, H., The double K+/Ca2+ sensor based on laser scanned silicon transducer (LSST) for multicomponent analysis 2003 10 Talanta. 59 (2003), H. 4 0039-9140 785 795 campus http://dx.doi.org/10.1016/S0039-9140(02)00620-3 Fachbereich Medizintechnik und Technomathematik OPUS4-1789 Wissenschaftlicher Artikel Wang, J., ; Krause, R., ; Block, K., ; Musameh, M., ; Mulchandani, A., ; Schöning, Michael Josef, schoening@fh-aachen.de Flow injection amperometric detection of OP nerve agents based on organophosphorus-hydrolase biosensor detector 2003 5 Biosensors & Bioelectronics. 18 (2003), H. 2-3 0956-5663 255 260 campus http://dx.doi.org/10.1016/S0956-5663(02)00178-1 Fachbereich Medizintechnik und Technomathematik OPUS4-1791 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Wang, Josepf, ; Krause, Robin, ; Block, Kirstin, ; Musameh, Mustafa, ; Mulchandani, Ashok, ; Mulchandani, Priti, ; Chen, Wilfred, Dual amperometric-potentiometric biosensor detection system for monitoring organophosphorus neurotoxins 2002 6 Analyica Chimica Acta. 469 (2002), H. 2 0378-4304 197 203 campus http://dx.doi.org/10.1016/S0003-2670(02)00666-9 Fachbereich Medizintechnik und Technomathematik OPUS4-1792 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Kloock, Joachim P., kloock@fh-aachen.de; Mourzina, Y., ; Schubert, J., A first step towards a microfabricated thin-film sensor array on the basis of chalcogenide glass materials 2002 9 Sensors. 2 (2002), H. 9 1424-8220 356 365 weltweit http://www.mdpi.net/sensors/papers/s20900356.pdf Fachbereich Medizintechnik und Technomathematik OPUS4-1793 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Simonis, A., ; Krings, T., ; Lüth, H., ; Wang, J., Evaluation of a chip-based thin-film / thick-film sensor hybrid for (bio-)chemical analysis 2002 3 Electroanalysis 14 13 955 958 campus http://www3.interscience.wiley.com/cgi-bin/fulltext/96516554/PDFSTART Fachbereich Medizintechnik und Technomathematik OPUS4-1794 Wissenschaftlicher Artikel Wagner, Torsten, torsten.wagner@fh-aachen.de; Rao, C., ; Otto, R., ; Yoshinobu, T., ; Kloock, Joachim P., ; Schöning, Michael Josef, schoening@fh-aachen.de Chipkarten-basierter Multikanal lichtadressierbarer potentiometrischer Sensor für analytische Anwendungen in flüssigen Medien Dresden TUDpress 2005 313 S Neue Herausforderungen und Anwendungen in der Sensortechnik : 7. Dresdner Sensor-Symposium ; 12. - 14. Dezember 2005, Dresden / [Forschungsgesellschaft für Messtechnik, Sensorik und Medizintechnik e.V.]. Gerald Gerlach ... (Hg.) 3-938863-29-3 Dresdner Beiträge zur Sensorik ; 24 11 14 Fachbereich Medizintechnik und Technomathematik OPUS4-1852 Wissenschaftlicher Artikel Poghossian, Arshak, poghossian@fh-aachen.de; Thust, M., ; Schroth, P., ; Steffen, A., ; Lüth, H., ; Schöning, Michael Josef, schoening@fh-aachen.de Penicillin detection by means of silicon-based field-effect structures 2001 16 Sensors and Materials. 13 (2001), H. 4 0392-2510 207 223 Fachbereich Medizintechnik und Technomathematik OPUS4-1855 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Buß, G., ; Lüth, H., ; Schultze, J.W., Modifications and characterization of a silicon-based microelectrode array 1999 11 Electrochimica Acta. 44 (1999), H. 21-22 0013-4686 3899 3910 bezahl http://dx.doi.org/10.1016/S0013-4686(99)00097-3 Fachbereich Medizintechnik und Technomathematik OPUS4-1856 Wissenschaftlicher Artikel Schroth, P., ; Schöning, Michael Josef, schoening@fh-aachen.de; Schütz, S., ; Malkoc, Ü., ; Steffen, A., ; Marso, M., ; Hummel, Hans E., ; Kordos, P., ; Lüth, H., Coupling of insect antennae to field-effect transistors for biochemical sensing 1999 5 Electrochimica Acta. 44 (1999), H. 21-22 3821 3826 campus http://dx.doi.org/10.1016/S0013-4686(99)00088-2 Fachbereich Medizintechnik und Technomathematik OPUS4-1857 Wissenschaftlicher Artikel Glück, O., ; Schöning, Michael Josef, schoening@fh-aachen.de; Lüth, H., ; Otto, A., ; Emons, H., Trace metal determination by dc resistance changes of microstructured thin gold film electrodes 1999 7 Electrochimica Acta. 44 (1999), H. 21-22 0013-4686 3761 3768 campus http://dx.doi.org/10.1016/S0013-4686(99)00081-X Fachbereich Medizintechnik und Technomathematik OPUS4-1858 Wissenschaftlicher Artikel Schmitt, G., ; Schultze, J.-W., ; Faßbender, F., ; Buß, G., ; Lüth, H., ; Schöning, Michael Josef, schoening@fh-aachen.de Passivation and corrosion of microelectrode arrays 1999 18 Electrochimica Acta. 44 (1999), H. 21-22 0013-4686 3865 3883 campus http://dx.doi.org/10.1016/S0013-4686(99)00094-8 Fachbereich Medizintechnik und Technomathematik OPUS4-1795 Wissenschaftlicher Artikel Ermelenko, Y., ; Yoshinobu, T, ; Mourzina, Y., ; Levichev, S., ; Furuichi, K., ; Vlasov, Y., ; Schöning, Michael Josef, schoening@fh-aachen.de; Iwasaki, H., Photocurable membranes for ion-selective light-addressable potentiometric sensors 2002 6 Sensors and Actuators B. 85 (2002), H. 1-2 0925-4005 79 85 campus http://dx.doi.org/10.1016/S0925-4005(02)00056-4 Fachbereich Medizintechnik und Technomathematik OPUS4-1796 Wissenschaftlicher Artikel Vlasov, Y. G., ; Mourzina, Y. G., ; Legin, A. V., ; Ermelenko, Y. E., ; Schubert, J., ; Schöning, Michael Josef, schoening@fh-aachen.de; Lüth, H., Solid-state thin film sensors based on chalcogenide materials prepared by planar technology and pulsed laser deposition 2002 5 Russian Journal of Applied Chemistry. 75 (2002), H. 3 1070-4272 351 356 campus http://dx.doi.org/10.1023/A:1016113931292 Fachbereich Medizintechnik und Technomathematik OPUS4-1797 Wissenschaftlicher Artikel Kurowski, A., ; Schultze, J., ; Lüth, H., ; Schöning, Michael Josef, schoening@fh-aachen.de Micro- and nanopatterning of sensor chips by means of macroporous silicon. 2002 5 Sensors and Actuators B. 83 (2002), H. 1-3 0925-4005 Selected Papers from TRANSDUCERS '01 EUROSENSORS XV 123 128 campus http://dx.doi.org/10.1016/S0925-4005(01)01054-1 Fachbereich Medizintechnik und Technomathematik OPUS4-1799 Wissenschaftlicher Artikel Groebel, Simone, groebel@fh-aachen.de; Werner, Frederik, f.werner@fh-aachen.de; Jörres, Niklas, ; Jansen, F., ; Kasper, Katharina, k.kasper@fh-aachen.de; Schiffels, Johannes, schiffels@fh-aachen.de; Sprenger, B., ; Baumann, Marcus, rektor@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de; Selmer, Thorsten, selmer@fh-aachen.de Entwicklung einer Sensor-Überwachung für Biogasanlagen auf Basis von Prozessdaten einer Parallelanlage Dresden TUDpress 2011 371 S. Ill., graph. Darst. 10. Dresdner Sensor-Symposium : Dresden, 5. - 7. Dezember 2011 ; miniaturisierte analytische Verfahren, Hochtemperatur-Sensoren, Sensoren für Bioprozess- und Verfahrenstechnik, Sensoren für die Medizin, Chemische Verfahrenstechnik, Lebensmittelanalytik, innovative Sensorlösungen, Sensoren für die Wasserqualität, Selbstüberwachung / Gerald Gerlach ... (Hg.) 978-3-942710-53-4 Dresdner Beiträge zur Sensorik 43 ; Dresdner Sensor-Symposium ; 10 ; 2011 ; Dresden ; Forschungsgesellschaft für Messtechnik, Sensorik und Medizintechnik ; Zehntes Dresdner Sensor-Symposium ; Dresdner Sensor-Symposium ; (10 ; 2011.12.05-07 ; Dresden) 81 84 Fachbereich Medizintechnik und Technomathematik OPUS4-1800 Wissenschaftlicher Artikel Ermelenko, Y., ; Yoshinobu, T., ; Mourzina, Y., ; Furuichi, K., ; Levichev, S., ; Vlasov, Y., ; Schöning, Michael Josef, schoening@fh-aachen.de; Iwasaki, H., Lithium sensor based on the laser scanning semiconductor transducer 2002 8 Analytica Chimica Acta. 459 (2002), H. 1 1 9 campus http://dx.doi.org/10.1016/S0003-2670(02)00102-2 Fachbereich Medizintechnik und Technomathematik OPUS4-1801 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de; Schultze, J. W., ; Lüth, H., Field-effect based multifunctional hybrid sensor module for the determination of both (bio-)chemical and physical paramters 2002 10 Proceedings of SPIE. 4576 (2002) 149 159 bezahl http://dx.doi.org/10.1117/12.456950 Fachbereich Medizintechnik und Technomathematik OPUS4-1802 Wissenschaftlicher Artikel Poghossian, Arshak, poghossian@fh-aachen.de; Berndsen, Lars, ; Lüth, Hans, ; Schöning, Michael Josef, schoening@fh-aachen.de Novel concepts for flow-rate and flow-direction determination by means of pH-sensitive ISFETs 2001 8 Proceedings of SPIE. 4560 (2001) 19 27 bezahl http://dx.doi.org/10.1117/12.443050 Fachbereich Medizintechnik und Technomathematik OPUS4-1803 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Schroth, Peter, ; Lüth, Hans, ; Hummel, Hans E., ; Schütz, Stefan, Insect chemoreceptors coupled to silicon transistors as innovative biosensors 2001 10 Proceedings of SPIE. 4205 (2001) 152 162 bezahl http://dx.doi.org/10.1117/12.417445 Fachbereich Medizintechnik und Technomathematik OPUS4-1804 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de; Yoshinobu, Tatsuo, ; Lüth, Hans, Semiconductor-based field-effect structures for chemical sensing 2001 10 188 198 bezahl http://dx.doi.org/10.1117/12.417449 Fachbereich Medizintechnik und Technomathematik OPUS4-1815 Wissenschaftlicher Artikel Poghossian, Arshak, poghossian@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de; Schroth, P., ; Simonis, A., ; Lüth, H., An ISFET-based penicillin sensor with high sensitivity, low detection limit and long lifetime 2001 7 Sensors and Actuators B. 76 (2001), H. 1-3 0925-4005 519 526 campus http://dx.doi.org/10.1016/S0925-4005(01)00609-8 Fachbereich Medizintechnik und Technomathematik OPUS4-1817 Wissenschaftlicher Artikel Ismail, A.B.M., ; Harada, T., ; Yoshinobu, T., ; Iwasaki, H., ; Schöning, Michael Josef, schoening@fh-aachen.de; Lüth, H., Investigation of pulsed laser-deposited Al2O3 as a high pH-sensitive layer for LAPS-based biosensing applications 2000 3 Sensors and Actuators B. 71 (2000), H. 3 0925-4005 169 172 campus http://dx.doi.org/10.1016/S0925-4005(99)00380-9 Fachbereich Medizintechnik und Technomathematik OPUS4-1818 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Schmidt, C., ; Schubert, J., ; Zander, W., ; Mesters, S., ; Kordos, P., ; Lüth, H., ; Legin, A., ; Seleznev, B., ; Vlasov, Y. G., Thin film sensors on the basis of chalcogenide glass materials prepared by pulsed laser deposition technique 2000 5 Sensors and Actuators B. 68 (2000), H. 1-3 0925-4005 254 259 campus http://dx.doi.org/10.1016/S0925-4005(00)00438-X Fachbereich Medizintechnik und Technomathematik OPUS4-1819 Wissenschaftlicher Artikel Mourzina, Y.G., ; Schöning, Michael Josef, schoening@fh-aachen.de; Schubert, J., ; Zander, W., ; Legin, A. V., ; Vlasov, Y. G., ; Kordos, P., ; Lüth, H., A new thin film Pb microsensor based on chalcogenide glasses 2000 5 Sensors and Actuators B. 71 (2000), H. 1-2 0925-4005 13 18 campus http://dx.doi.org/10.1016/S0925-4005(00)00557-8 Fachbereich Medizintechnik und Technomathematik OPUS4-1820 Wissenschaftlicher Artikel Faßbender, F., ; Schmitt, G., ; Schöning, Michael Josef, schoening@fh-aachen.de; Lüth, H., ; Buß, G., ; Schultze, J. W., Optimization of passivation layers for corrosion protection of silicon-based microelectrode arrays 2000 5 Sensors and Actuators B. 68 (2000), H. 1-3 0925-4005 128 133 campus http://dx.doi.org/10.1016/S0925-4005(00)00472-X Fachbereich Medizintechnik und Technomathematik OPUS4-1823 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Buß, G., ; Faßbender, F., ; Glück, O., ; Schmitt, G., ; Schultze, J. W., ; Lüth, H., A silicon-based microelectrode array for chemical analysis 2000 3 Sensors and Actuators B. 65 (2000), H. 1-3 0925-4005 284 287 campus http://dx.doi.org/10.1016/S0925-4005(99)00338-X Fachbereich Medizintechnik und Technomathematik OPUS4-1824 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Malkoc, Ü., ; Thust, M., ; Steffen, A., ; Kordos, P., ; Lüth, H., Novel electrochemical sensors with structured and porous semiconductor/insulator capacitors 2000 2 Sensors and Actuators B. 65 (2000), H. 1-3 0925-4005 288 290 campus http://dx.doi.org/10.1016/S0925-4005(99)00349-4 Fachbereich Medizintechnik und Technomathematik OPUS4-1825 Wissenschaftlicher Artikel Schütz, S., ; Schöning, Michael Josef, schoening@fh-aachen.de; Schroth, P., ; Weißbecker, B., ; Kordos, P., ; Lüth, H., ; Hummel, Hans E., An insectbased BioFET as a bioelectronic nose 2000 4 Sensors and Actuators B. 65 (2000), H. 1-3 0925-4005 291 295 campus http://dx.doi.org/10.1016/S0925-4005(99)00325-1 Fachbereich Medizintechnik und Technomathematik OPUS4-1765 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de; Schultze, Joachim W., Measuring seven parameters by two ISFET modules in a microcell set-up 2003 3 Int. Journal of Computational Engineering Science. 4 (2003), H. 2 1465-8763 257 260 bezahl http://dx.doi.org/10.1142/S1465876303001022 Fachbereich Medizintechnik und Technomathematik OPUS4-1768 Wissenschaftlicher Artikel Yoshinobu, T., ; Schöning, Michael Josef, schoening@fh-aachen.de; Otto, R., ; Furuichi, K., ; Mourzina, Y., ; Ermelenko, Y., ; Iwasaki, H., Portable light-addressable potentiometric sensor (LAPS) for multisensor applications 2003 4 Sensors and Actuators B. 95 (2003), H. 1-3 0925-4005 352 356 campus http://dx.doi.org/10.1016/S0925-4005(03)00437-4 Fachbereich Medizintechnik und Technomathematik OPUS4-1769 Wissenschaftlicher Artikel Poghossian, Arshak, poghossian@fh-aachen.de; Berndsen, Lars, ; Schöning, Michael Josef, schoening@fh-aachen.de Chemical sensor as physical sensor: ISFET-based flowvelocity, flow-direction and diffusion-coefficient sensor 2003 6 Sensors and Actuators B. 95 (2003), H. 1-3 0925-4005 384 390 campus http://dx.doi.org/10.1016/S0925-4005(03)00444-1 Fachbereich Medizintechnik und Technomathematik OPUS4-1770 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Krause, R., ; Block, K., ; Musahmeh, M., ; Mulchandani, A., ; Wang, J., A dual amperometric/potentiometric FIA-based biosensor for the distinctive detection of organophosphorus pesticides 2003 5 Sensors and Actuators B. 95 (2003), H. 1-3 0925-4005 291 296 campus http://dx.doi.org/10.1016/S0925-4005(03)00426-X Fachbereich Medizintechnik und Technomathematik OPUS4-1771 Wissenschaftlicher Artikel Mourzina, Y., ; Mai, T., ; Poghossian, Arshak, poghossian@fh-aachen.de; Ermolenko, Y., ; Yoshinobu, T., ; Vlasov, Y., ; Iwasaki, H., ; Schöning, Michael Josef, schoening@fh-aachen.de K+-selective field-effect sensors as transducers for bioelectronic applications 2003 6 Electrochimica Acta. 48 (2003), H. 20-22 0013-4686 3333 3339 campus http://dx.doi.org/10.1016/S0013-4686(03)00402-X Fachbereich Medizintechnik und Technomathematik OPUS4-1772 Wissenschaftlicher Artikel Poghossian, Arshak, poghossian@fh-aachen.de; Schultze, J. W., ; Schöning, Michael Josef, schoening@fh-aachen.de Application of a (bio-)chemical sensor (ISFET) for the detection of physical parameters in liquids 2003 8 Electrochimica Acta. 48 (2003), H. 20-22 3289 3297 campus http://dx.doi.org/10.1016/S0013-4686(03)00392-X Fachbereich Medizintechnik und Technomathematik OPUS4-1773 Wissenschaftlicher Artikel Bressel, A., ; Schultze, J.W., ; Khan, W., ; Wolfaardt, G. M., ; Rohns, H.-P., ; Irmscher, R., ; Schöning, Michael Josef, schoening@fh-aachen.de High resolution gravimetric, optical and electrochemical investigations of microbial biofilm formation in aqueous systems 2003 9 Electrochimica Acta. 48 (2003), H. 20-22 0013-4686 3363 3372 campus http://dx.doi.org/10.1016/S0013-4686(03)00406-7 Fachbereich Medizintechnik und Technomathematik OPUS4-1779 Wissenschaftlicher Artikel Simonis, A., ; Lüth, H., ; Wang, J., ; Schöning, Michael Josef, schoening@fh-aachen.de Strategies of miniaturised reference electrodes integrated in a silicon-based „one chip" pH sensor 2003 9 Sensors. 3 (2003), H. 9 1424-8220 330 339 weltweit http://www.mdpi.net/sensors/papers/s30900330.pdf Fachbereich Medizintechnik und Technomathematik OPUS4-1780 Wissenschaftlicher Artikel Poghossian, Arshak, poghossian@fh-aachen.de; Yoshinobu, Tatsuo, ; Schöning, Michael Josef, schoening@fh-aachen.de Flow-velocity microsensors based on semiconductor field-effect structures 2003 10 Sensors. 3 (2003), H. 7 1424-8220 202 212 weltweit http://dx.doi.org/10.3390/s30700202 Fachbereich Medizintechnik und Technomathematik OPUS4-1781 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Thust, M., Die „Zukunftswerkstatt Biosensorik" - ein Netzwerk für Lehre, Forschungs und Wirtschaft 2003 1 Fachblatt Fachhochschule Aachen (2003) 1430-7707 6 7 weltweit http://www.fh-aachen.de/fileadmin/groups/pressestelle/fachblatt/fachblatt_1_2003.pdf Fachbereich Medizintechnik und Technomathematik OPUS4-1782 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Arzdorf, M., ; Mulchandani, P., ; Chen, W., ; Mulchandani, A., Towards a capacitive enzyme sensor for direct determination of organophosphorus pesticides: Fundamentals studies and aspects of development 2003 8 Sensors. 3 (2003), H. 6 1424-8220 119 127 weltweit http://www.mdpi.net/sensors/papers/s30600119.pdf Fachbereich Medizintechnik und Technomathematik OPUS4-1783 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Arzdorf, M., ; Mulchandani, P., ; Chen, W., ; Mulchandani, A., A capacitive field-effect sensor for the direct determination of organophosphorus pesticides 2003 5 Sensors and Actuators B. 91 (2003), H. 1-3 0925-4005 92 97 campus http://dx.doi.org/10.1016/S0925-4005(03)00071-6 Fachbereich Medizintechnik und Technomathematik OPUS4-1784 Wissenschaftlicher Artikel Poghossian, Arshak, poghossian@fh-aachen.de; Schultze, J. W., ; Schöning, Michael Josef, schoening@fh-aachen.de Multi-parameter detection of (bio-)chemical and physical quantities using an identical transducer principle 2003 8 Sensors and Actuators B. 91 (2003), H. 1-3 0925-4005 83 91 campus http://dx.doi.org/10.1016/S0925-4005(03)00070-4 Fachbereich Medizintechnik und Technomathematik OPUS4-1805 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Schubert, Jürgen, ; Zander, Willy, ; Müller-Veggian, Mattea, mueller-veggian@opus.fh-aachen.de Pulsed laser deposition as a novel preparation technique for chemical microsensors 1999 10 Proceedings of SPIE 3857, Chemical Microsenors and Applications II, 124 (November 18, 1999). 3857 (1999) 124 134 bezahl http://dx.doi.org/10.1117/12.370281 Fachbereich Medizintechnik und Technomathematik OPUS4-1806 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Glück, O., ; Kordos, P., ; Lüth, H., ; Emons, H., Thin film electrodes for trace metal analysis by dc resistance changes 1999 8 Proceedings of SPIE. 3857 (1999) 135 143 bezahl http://dx.doi.org/10.1117/12.370279 Fachbereich Medizintechnik und Technomathematik OPUS4-1807 Wissenschaftlicher Artikel Mourzina, Y. G., ; Yoshinobu, T., ; Schubert, J., ; Lüth, H., ; Iwasaki, H., ; Schöning, Michael Josef, schoening@fh-aachen.de Ion-selective lightaddressable potentiometric sensor (LAPS) with chalcogenide thin film by pulsed laser deposition 2001 4 Sensors and Actuators B. 80 (2001), H. 2 0925-4005 136 140 campus http://dx.doi.org/10.1016/S0925-4005(01)00906-6 Fachbereich Medizintechnik und Technomathematik OPUS4-1808 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Mourzina, Y. G., ; Schubert, J., ; Zander, W., ; Legin, A., ; Vlasov, Y. G., ; Lüth, H., Can pulsed laser deposition serve as an advanced technique in fabricating chemical sensors? 2001 5 Sensors and Actuators B. 78 (2001), H. 1-3 0925-4005 Selected Papers form Eurosensors XIV 273 278 campus http://dx.doi.org/10.1016/S0925-4005(01)00825-5 Fachbereich Medizintechnik und Technomathematik OPUS4-1809 Wissenschaftlicher Artikel Schroth, P., ; Schöning, Michael Josef, schoening@fh-aachen.de; Lüth, H., ; Weißbecker, B., ; Hummel, Hans E., ; Schütz, S., Extending the capabilities of an antenna/chip biosensor by employing various insect species 2001 4 Sensors and Actuators B. 78 (2001), H. 1-3 0925-4005 1 5 campus http://dx.doi.org/10.1016/S0925-4005(01)00783-3 Fachbereich Medizintechnik und Technomathematik OPUS4-1810 Wissenschaftlicher Artikel Poghossian, Arshak, poghossian@fh-aachen.de; Yoshinobu, Tatsuo, ; Simonis, A., ; Ecken, H., ; Lüth, Hans, ; Schöning, Michael Josef, schoening@fh-aachen.de Penicillin detection by means of field-effect based sensors: EnFET, capacitive EIS sensor or LAPS? 2001 5 Sensors and Actuators B. 78 (2001), H. 1-3 0925-4005 237 242 campus http://dx.doi.org/10.1016/S0925-4005(01)00819-X Fachbereich Medizintechnik und Technomathematik OPUS4-1811 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Hüllenkremer, B., ; Glück, O., ; Lüth, H., ; Emons, H., Voltohmmetry - a novel sensing principle for heavy metal determination in aqueous solutions 2001 5 Sensors and Actuators B. 78 (2001), H. 1-3 0925-4005 275 280 campus http://dx.doi.org/10.1016/S0925-4005(01)00582-2 Fachbereich Medizintechnik und Technomathematik OPUS4-1812 Wissenschaftlicher Artikel Yoshinobu, T., ; Ecken, H., ; Poghossian, Arshak, poghossian@fh-aachen.de; Lüth, H., ; Iwasaki, H., ; Schöning, Michael Josef, schoening@fh-aachen.de Alternative sensor materials for light-addressable potentiometric sensors 2001 4 Sensors and Actuators B. 76 (2001), H. 1-3 0925-4005 388 392 campus http://dx.doi.org/10.1016/S0925-4005(01)00646-3 Fachbereich Medizintechnik und Technomathematik OPUS4-1813 Wissenschaftlicher Artikel Poghossian, Arshak, poghossian@fh-aachen.de; Baade, A., ; Emons, H., ; Schöning, Michael Josef, schoening@fh-aachen.de Application of ISFET for pH measurements in rain droplets 2001 4 Sensors and Actuators B. 76 (2001), H. 1-3 0925-4005 634 638 campus http://dx.doi.org/10.1016/S0925-4005(01)00659-1 Fachbereich Medizintechnik und Technomathematik OPUS4-1814 Wissenschaftlicher Artikel Schubert, J., ; Schöning, Michael Josef, schoening@fh-aachen.de; Mourzina, Y. G., ; Legin, A. V., ; Vlasov, Y. G., ; Zander, W., ; Lüth, H., Multicomponent thin films for electrochemical sensor applications prepared by pulsed laser deposition 2001 3 Sensors and Actuators B. 76 (2001), H. 1-3 0925-4005 327 330 campus http://dx.doi.org/10.1016/S0925-4005(01)00616-5 Fachbereich Medizintechnik und Technomathematik OPUS4-1869 Wissenschaftlicher Artikel Mourzina, Yu. G., ; Schubert, J, ; Zander, W., ; Legin, A., ; Vlasov, Y. G., ; Lüth, H., ; Schöning, Michael Josef, schoening@fh-aachen.de Development of multisensor systems based on chalcogenide thin film chemical sensors for the simultaneous multicomponent analysis of metal ions in complex solutions Amsterdam [u.a.] Elsevier [u.a.] 2001 385 S. : Ill., graph. Darst. Scaling down in electrochemistry : electrochemical micro- and nanosystem technology ; proceedings of the 3rd International Symposium on Electrochemical Microsystem Technologies, Garmisch-Patenkirchen, Germany, 11 - 15 September 2000 / ed. by J. W. Schultz 0-08-044014-2 251 263 Fachbereich Medizintechnik und Technomathematik OPUS4-1874 Wissenschaftlicher Artikel Yoshinobu, T., ; Ecken, H., ; Poghossian, Arshak, poghossian@fh-aachen.de; Simonis, A., ; Iwasaki, H., ; Lüth, H., ; Schöning, Michael Josef, schoening@fh-aachen.de Constant-current-mode LAPS (CLAPS) for the detection of penicillin 2001 3 Electroanalysis. 13 (2001), H. 8-9 1040-0397 733 736 campus http://www3.interscience.wiley.com/cgi-bin/abstract/82502248/ABSTRACT Fachbereich Medizintechnik und Technomathematik OPUS4-1876 Wissenschaftlicher Artikel Emons, H., ; Baade, A., ; Schöning, Michael Josef, schoening@fh-aachen.de Voltammetric determination of heavy metals in microvolumes of rain water 2000 5 Electroanalysis. 12 (2000), H. 15 1040-0397 1171 1176 campus http://www3.interscience.wiley.com/cgi-bin/abstract/75001059/ABSTRACT Fachbereich Medizintechnik und Technomathematik OPUS4-1877 Wissenschaftlicher Artikel Mourzina, Y. G., ; Schöning, Michael Josef, schoening@fh-aachen.de; Schubert, J., ; Zander, W., ; Legin, A. V., ; Vlasov, Y. G., ; Lüth, H., Copper, cadmium and thallium thin film sensors based on chalcogenide glasses 2001 7 Analytica Chimica Acta. 433 (2001) 0378-4304 103 110 campus http://dx.doi.org/10.1016/S0003-2670(00)01384-2 Fachbereich Medizintechnik und Technomathematik OPUS4-1878 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Thust, M., ; Vetter, J., ; Kordos, P. (u.a.), A long-term stable penicillin-sensitive potentiometric biosensor with enzyme immobilized by heterobifunctional crosslinking 1996 6 0378-4304 115 121 campus http://dx.doi.org/10.1016/0003-2670(95)00619-2 Fachbereich Medizintechnik und Technomathematik OPUS4-1860 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Ronkel, F., ; Crott, M., ; Thust, M. (u.a.), Miniaturization of potentiometric sensors using porous silicon microtechnology 1997 8 Electrochimica Acta. 42 (1997), H. 22 0013-4686 3185 3193 bezahl http://dx.doi.org/10.1016/S0013-4686(97)00172-2 Fachbereich Medizintechnik und Technomathematik OPUS4-1862 Wissenschaftlicher Artikel Lüth, H., ; Thust, M., ; Steffen, A., ; Kordos, P., ; Schöning, Michael Josef, schoening@fh-aachen.de Biochemical sensors with structured and porous silicon capacitors 2000 4 Materials Science and Engineering B. 69-70 (2000) 0921-5107 104 108 campus http://dx.doi.org/10.1016/S0921-5107(99)00275-5 Fachbereich Medizintechnik und Technomathematik OPUS4-1863 Wissenschaftlicher Artikel Emons, H., ; Glück, O., ; Hüllenkremer, B., ; Schöning, Michael Josef, schoening@fh-aachen.de Voltohmmetry as an alternative detection method at polycrystalline metal film electrodes 2001 3 Electroanalysis. 13 (2001), H. 8-9 1040-0397 677 680 campus http://www3.interscience.wiley.com/cgi-bin/abstract/82502240/ABSTRACT Fachbereich Medizintechnik und Technomathematik OPUS4-1866 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Mourzina, Yu.G., ; Schubert, J., ; Zander, W., ; Legin, A., ; Vlasov, Y. G., ; Lüth, H., Pulsed laser deposition - an innovative technique for preparing inorganic thin films 2001 5 Electroanalysis. 13 (2001), H. 8-9 1040-0397 727 732 campus http://www3.interscience.wiley.com/cgi-bin/abstract/82502247/ABSTRACT Fachbereich Medizintechnik und Technomathematik OPUS4-1879 Wissenschaftlicher Artikel Emons, H., ; Hüllenkremer, B., ; Schöning, Michael Josef, schoening@fh-aachen.de Detection of metal ions in aqueous solutions by voltohmmetry 2001 4 Fresenius' Journal of Analytical Chemistry. 369 (2001), H. 1 0937-0633 42 46 campus http://dx.doi.org/10.1007/s002160000587 Fachbereich Medizintechnik und Technomathematik OPUS4-1880 Wissenschaftlicher Artikel Ge, B., ; Meyer, T., ; Schöning, Michael Josef, schoening@fh-aachen.de; Wollenberger, U., ; Lisdat, F., , Cytochrome c' from Chromatium vinosum on gold electrodes 2000 4 Electrochemistry Communications. 2 (2000), H. 8 1388-2481 557 561 campus http://dx.doi.org/10.1016/S1388-2481(00)00082-5 Fachbereich Medizintechnik und Technomathematik OPUS4-1881 Wissenschaftlicher Artikel Schmitt, G., ; Faßbender, F., ; Lüth, H., ; Schöning, Michael Josef, schoening@fh-aachen.de; Schultze, J. W., ; Buß, G., Passivation and corrosion of microelectrode arrays 2000 5 Materials and Corrosion. 51 (2000), H. 1 0947-5117 20 25 campus http://www3.interscience.wiley.com/cgi-bin/fulltext/69500186/PDFSTART Fachbereich Medizintechnik und Technomathematik OPUS4-1882 Wissenschaftlicher Artikel Schubert, J., ; Schöning, Michael Josef, schoening@fh-aachen.de; Schmidt, C., ; Siegert, M., ; Mesters, S., ; Zander, W., ; Kordos, P., ; Lüth, H., ; Legin, A., ; Mourzina, Y. G., ; Seleznev, B., ; Vlasov, Y. G., Chalcogenide-based thin film sensors prepared by pulsed laser deposition technique 1999 2 Applied Physics A. 69, (1999), H. Supplement 1 0947-8396 803 805 10.1007/s003390051534 campus Fachbereich Medizintechnik und Technomathematik OPUS4-1883 Wissenschaftlicher Artikel Schroth, P., ; Schöning, Michael Josef, schoening@fh-aachen.de; Kordos, P., ; Lüth, H., ; Schütz, S., ; Weißbecker, B., ; Hummel, Hans E., Insectbased BioFETs with improved signal characteristics 1999 5 Biosensors & Bioelectronics. 14 (1999), H. 3 303 308 campus http://dx.doi.org/10.1016/S0956-5663(98)00131-6 Fachbereich Medizintechnik und Technomathematik OPUS4-1884 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Lüth, H., ; Thust, M., Neue Ansätze für Chemo- und Biosensoren in Siliziumtechnik 1997 4 Physikalische Blätter. 53 (1997), H. 5 0031-9279 423 427 Fachbereich Medizintechnik und Technomathematik OPUS4-1887 Wissenschaftlicher Artikel Thust, M., ; Schöning, Michael Josef, schoening@fh-aachen.de; Schroth, P., ; Malkoc, Ü., ; Dicker, C. I., ; Steffen, A., ; Kordos, P., ; Lüth, H., Enzyme immobilisation on planar and porous silicon substrates for biosensor applications 1999 6 Journal of Molecular Catalysis B: Enzymatic. 7 (1999), H. 1-4 1381-1177 77 83 campus http://dx.doi.org/10.1016/S1381-1177(99)00023-5 Fachbereich Medizintechnik und Technomathematik OPUS4-1888 Wissenschaftlicher Artikel Schmitt, G., ; Faßbender, F., ; Lüth, H., ; Schöning, Michael Josef, schoening@fh-aachen.de; Buss, G., ; Kranzmann, A., ; Gramberg, U., Korrosionsschutzwirkung von Passivierungsschichten am Beispiel eines Mikroelektrodenarrays Weinheim [u.a.] Wiley-VCH 1999 404 S. Werkstoffe für die Energietechnik / Symposium 3 3-527-29940-8 Serie Werkstoffwoche '98 ; 3 345 350 Fachbereich Medizintechnik und Technomathematik OPUS4-1889 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Thust, M., ; Steffen, A., ; Müller-Veggian, Mattea, mueller-veggian@opus.fh-aachen.de Kapazitives Sensorarray in Siliziumtechnik für die Prozeßüberwachung 1998 6 ITG-Fachbericht. 148 (1998) 0341-0196 257 263 Fachbereich Medizintechnik und Technomathematik OPUS4-1891 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Thust, M., ; Kordos, P., ; Lüth, H., ; Ronkel, F., ; Schultze, J. W., Halbleiter-Schichtstrukturen mit porösem Silizium als Chemo- und Biosensoren 1998 7 ITG-Fachbericht. 148 (1998) 0341-0196 33 40 Fachbereich Medizintechnik und Technomathematik OPUS4-1893 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Hoffmann, W., ; Bruns, M., ; Ache, H.J. (u.a.), Chemical microsensors and evaporated silver halide layers 1993 8 Bulgarian Chemical Communications. 26 (1993), H. 3-4 0324-1130 402 410 Fachbereich Medizintechnik und Technomathematik OPUS4-1899 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Thust, M., Miniaturisierbare Halbleitersensoren für die Penicillinbestimmung in der Biotechnologie 1996 3 MessTec. 3 (1996) 0947-4234 82 85 Fachbereich Medizintechnik und Technomathematik OPUS4-1960 Wissenschaftlicher Artikel Schroth, P., ; Schöning, Michael Josef, schoening@fh-aachen.de; Schütz, S., ; Steffen, A., ; Weißbecker, B., ; Hummel, Hans E., ; Kordos, P., ; Lüth, H., Nachweis von organischen Duftstoffen durch Biosensoren auf der Basis von Insektenantennen Düsseldorf: VDI-Verl. 2000 1087s.: Ill., graph. Darst. Gesellschaft Mess- und Automatisierungstechnik: Sensoren und Meßsysteme 2000 : Tagung Ludwigsburg, 13. und 14. März 2000 / VDI/VDE-Gesellschaft Meß- und Automatisierungstechnik 3-18-091530-7 VDI-Berichte; 1530 107 114 Fachbereich Medizintechnik und Technomathematik OPUS4-1961 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Crott, M., ; Ronkel, F., ; Thust, M., ; Schultze, J. W., ; Kordos, P., ; Lüth, H., Investigations on porous silicon layers with regard to chemical microsensor applications Bellingham, Wash. SPIE 1996 XVIII, 1022 S.: Ill. Third International Conference on Intelligent Materials : Lyon, 3-4-5 June 1996, Center of Congress "L'Espace Tête d'Or" / [publ. by SPIE, the International Society for Optical Engineering]. General chair/ed. by: P. F. Gobin 0819421650 International Conference on Intelligent Materials ; (3, 1996, Lyon) 275 280 Fachbereich Medizintechnik und Technomathematik OPUS4-1962 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Schaub, A., ; Beckers, L., ; Zander, W., Dünne Al2O3-Schichten für pH-Sensoren auf Halbleiterbasis mittels Laserablation Düsseldorf VDI-Verl. 1996 624 S. : Ill., graph. Darst. Gesellschaft Mess- und Automatisierungstechnik: Sensoren und Messysteme : Tagung Bad Nauheim, 11. bis 13. März 1996 / VDI/VDE-Gesellschaft Meß- und Automatisierungstechnik. 3-18-091255-3 VDI-Berichte; 1255 381 386 Fachbereich Medizintechnik und Technomathematik OPUS4-1963 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Thust, M., ; Steffen, A., ; Kordos, P., ; Lüth, H., ; Kauffmann, F., ; Hoffmann, B., Halbleiter-Biosensoren für den Penicillin-Nachweis in wäßrigen Lösungen Düsseldorf VDI-Verl. 1996 624 S. : Ill., graph. Darst. Gesellschaft Mess- und Automatisierungstechnik: Sensoren und Messysteme : Tagung Bad Nauheim, 11. bis 13. März 1996 / VDI/VDE-Gesellschaft Meß- und Automatisierungstechnik. 3-18-091255-3 VDI-Berichte; 1255 143 148 Fachbereich Medizintechnik und Technomathematik OPUS4-1964 Wissenschaftlicher Artikel Wagner, Torsten, torsten.wagner@fh-aachen.de; Yoshinobu, T., ; Rao, C., ; Otto, R., ; Schöning, Michael Josef, schoening@fh-aachen.de „All-in-one" solid-state device based on a lightaddressable potentiometric sensor platform Piscataway, NJ IEEE Operations Center 2005 3 Transducers '05 : the 13th International Conference on Solid-State Sensors, Actuators and Microsystems ; Seoul, Korea, [June 5 - 9, 2005] ; digest of technical papers / sponsored by Korean Sensors Society. Technical co-sponsors: IEEE Electron Devices Society 0-7803-83995-6 International Conference on Solid State Sensors, Actuators and Microsystems ; (13, 2005, Seoul) 1872 1875 Fachbereich Medizintechnik und Technomathematik OPUS4-1965 Wissenschaftlicher Artikel Yoshinobu, T., ; Yasuhito, U., ; Iwasaki, H., ; Näther, Niko, naether@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de; Koudelka-Hep, M., Applications of the light-addressable potentiometric sensor to microfluidic devices Roma 2004 790 S.: Ill., graph. Darst. 1 CD-ROM Digest of technical papers : September 12 - 15, 2004, Rome, Italy, Pontificia Universitas Sancto Thoma Aquinate in Urbe / [conference chairperson: C. Di Natale]. 88-7621-282-5 Eurosensors ; (18, 2004, Roma) 434 437 Fachbereich Medizintechnik und Technomathematik OPUS4-1966 Wissenschaftlicher Artikel Poghossian, Arshak, poghossian@fh-aachen.de; Cherstvy, A., ; Schöning, Michael Josef, schoening@fh-aachen.de Possibilities and limitations of label-free detection of DNA hybridization with field-effect based devices Roma 2004 790 S.: Ill., graph. Darst. 1 CD-ROM Digest of technical papers : September 12 - 15, 2004, Rome, Italy, Pontificia Universitas Sancto Thoma Aquinate in Urbe / [conference chairperson: C. Di Natale]. 88-7621-282-5 Eurosensors ; (18, 2004, Roma) 173 176 Fachbereich Medizintechnik und Technomathematik OPUS4-1967 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Brinkmann, D., ; Demuth, C., ; Poghossian, Arshak, poghossian@fh-aachen.de CIP (cleaning-in-place)-suitable „non-glass" pH sensor based on a Ta2O5-gate EIS structure Roma 2004 790 S.: Ill., graph. Darst. 1 CD-ROM Digest of technical papers : September 12 - 15, 2004, Rome, Italy, Pontificia Universitas Sancto Thoma Aquinate in Urbe / [conference chairperson: C. Di Natale]. 88-7621-282-5 Eurosensors ; (18, 2004, Roma) 857 860 Fachbereich Medizintechnik und Technomathematik OPUS4-1968 Wissenschaftlicher Artikel Ermolenko, Y.E., ; Vlasov, Y.G., ; Kolodnikov, V.V., ; Shabaldkin, D. A., ; Kloock, Joachim P., ; Schöning, Michael Josef, schoening@fh-aachen.de Diffusion of radioactive tracers (204Tl, 110mAg) and ionic conductivity in membrane materials for the chemical sensors Jülich Forschungszentrum Jülich, Zentralbibliothek 2004 XXXII, 794 S : Ill., graph. Darst. Advances in nuclear and radiochemistry : extended abstracts of papers presented at the Sixth International Conference on Nuclear and Radiochemistry (NRC-6), 29 August to 3 September 2004, Aachen, Germany ; in cooperation with University of Cologne, GDCh, FECS, OECD-NEA and IAEA / Syed M. Qaim ... (eds.). 3893363629 Schriften des Forschungszentrums Jülich Reihe Allgemeines und Interdisziplinäres ; 3. International Conference on Nuclear and Radiochemistry ; (6, 2004, Aachen) 483 485 Fachbereich Medizintechnik und Technomathematik OPUS4-1969 Wissenschaftlicher Artikel Mourzina, I.G., ; Yoshinobu, T., ; Ermolenko, Y.E., ; Vlasov, Y. G., ; Schöning, Michael Josef, schoening@fh-aachen.de; Iwasaki, H., Immobilization of urease and cholinesterase on the surface of semiconductor transducer for the development of light-addressable potentiometric sensors Fukuoka Japan Association of Chemical Sensors 2004 887, 12 S : Ill., graph. Darst. Technical digest of the 10th International Meeting on Chemical Sensors, July 11 - 14, 2004, Tsukuba, Japan / Japan Association of Chemical Sensors Chemical sensors ; 20.2004 Suppl. B. IMCS ; (10, 2004, Tsukuba) ; International Meeting on Chemical Sensors ; (10 : ; 2004.07.11-14 : ; Tsukuba) 788 789 Fachbereich Medizintechnik und Technomathematik OPUS4-2021 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Schmidt, C., ; Schubert, J., ; Zander, W., ; Kordos, P., ; Lüth, H., ; Legin, A., ; Seleznev, B., ; Vlasov, Y. G., Thin film sensors on the basis of chalcogenide glass materials prepared by pulsed laser deposition technique The Hague, The Netherlands 1999 1 CD-ROM Proceedings : The Hague, The Netherlands, September 12 - 15, 1999 / [ed. by M. Bartek]. Vol 1. 90-76699-02-X Eurosensors ; (13, 1999, 's-Gravenhage) ; Eurosensors ; (13 : ; 1999.09.12-15 : ; The Hague) ; European Conference on Solid-State Transducers ; (13 : ; 1999.09.12-15 : ; The Hague) 847 850 Fachbereich Medizintechnik und Technomathematik OPUS4-2022 Wissenschaftlicher Artikel Faßbender, F., ; Schmitt, G., ; Schöning, Michael Josef, schoening@fh-aachen.de; Lüth, H., ; Buß, G., ; Schultze, J. W., Passivation and corrosion of microsensor devices exemplified at microelectrode arrays The Hague, The Netherlands 1999 1 CD-ROM Proceedings : The Hague, The Netherlands, September 12 - 15, 1999 / [ed. by M. Bartek]. Vol 1. 90-76699-02-X Eurosensors ; (13, 1999, 's-Gravenhage) ; Eurosensors ; (13 : ; 1999.09.12-15 : ; The Hague) ; European Conference on Solid-State Transducers ; (13 : ; 1999.09.12-15 : ; The Hague) 953 956 Fachbereich Medizintechnik und Technomathematik OPUS4-2023 Wissenschaftlicher Artikel Schroth, P., ; Schöning, Michael Josef, schoening@fh-aachen.de; Schütz, S., ; Epanya, P., ; Steffen, A., ; Weißbecker, B., ; Hummel, Hans E., ; Kordos, P., ; Lüth, H., Improving the bioelectronic interface of an antenna/chip biosensor - technological aspects The Hague, The Netherlands 1999 1 CD-ROM Proceedings : The Hague, The Netherlands, September 12 - 15, 1999 / [ed. by M. Bartek]. Vol 1. 90-76699-02-X Eurosensors ; (13, 1999, 's-Gravenhage) ; Eurosensors ; (13 : ; 1999.09.12-15 : ; The Hague) ; European Conference on Solid-State Transducers ; (13 : ; 1999.09.12-15 : ; The Hague) 569 572 Fachbereich Medizintechnik und Technomathematik OPUS4-2024 Wissenschaftlicher Artikel Thust, M., ; Poghossian, Arshak, poghossian@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de; Naser, S., ; Müller-Veggian, Mattea, mueller-veggian@opus.fh-aachen.de; Kordos, P., ; Lüth, H., Crosssensitivity of a capacitive penicillin sensor combined with a diffusion barrier The Hague, The Netherlands 1999 1 CD-ROM Proceedings : The Hague, The Netherlands, September 12 - 15, 1999 / [ed. by M. Bartek]. Vol 1. 90-76699-02-X Eurosensors ; (13, 1999, 's-Gravenhage) ; Eurosensors ; (13 : ; 1999.09.12-15 : ; The Hague) ; European Conference on Solid-State Transducers ; (13 : ; 1999.09.12-15 : ; The Hague) 573 576 Fachbereich Medizintechnik und Technomathematik OPUS4-2025 Wissenschaftlicher Artikel Thust, M., ; Poghossian, Arshak, poghossian@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de; Naser, S., ; Müller-Veggian, Mattea, mueller-veggian@opus.fh-aachen.de; Kordos, P., ; Lüth, H., Cross-sensitivity of a capacitive penicillin sensor combined with a diffusion barrier The Hague, The Netherlands 1999 1 CD-ROM Proceedings : The Hague, The Netherlands, September 12 - 15, 1999 / [ed. by M. Bartek]. - Vol 1. 90-76699-02-X Eurosensors <13, 1999, 's-Gravenhage> ; Eurosensors <13, 1999, The Hague> ; European Conference on Solid-State Transducers <13, 1999, The Hague> 573 576 Fachbereich Medizintechnik und Technomathematik OPUS4-2027 Wissenschaftlicher Artikel Herber, R., ; Ernst, S., ; Buß, G., ; Schöning, Michael Josef, schoening@fh-aachen.de; Baltruschat, H., Detection of hydrocarbons in air and water by adsorption on Pt electrodes using continuous impedance measurements Pennington, NJ Electrochemical Society 1999 XIII, 268, Ill. Proceedings of the Symposium on New Directions in Electroanalytical Chemistry II : [held at the 195th Meeting of the Electrochemical Society in Seattle, Washington on May 3 and 4, 1999] / Physical Electrochemistry, Sensor, and Organic and Biological Electrochemistry Divisions. Ed.: J. Leddy, P. Vanysek, M.D. Porter 1-56677-227-3 Symposium on New Directions in Electroanalytical Chemistry ; (2, 1999, Seattle, Wash.) 168 177 Fachbereich Medizintechnik und Technomathematik OPUS4-2028 Wissenschaftlicher Artikel Schütz, S., ; Czynski, J., ; Hummel, Hans E., ; Schöning, Michael Josef, schoening@fh-aachen.de; Schroth, P., ; Kordos, P., ; Lüth, H., Insect meets microelectronics: A BioFET as a first step to bioelectronic microsystems Amsterdam [u.a.] Elsevier 2000 3 Transducers '99 : proceedings of the Tenth International Conference on Solid-State Sensors and Actuators ; 7 - 10 June, 1999, Sendai, Japan / ed.: S. Middelhoek International Conference on Solid State Sensors and Actuators <10, 1999, Sendai, Miyagi-ken> ; Transducers '99 ; (10 : ; 1999.06.07-10 : ; Sendai) 1104 1107 Fachbereich Medizintechnik und Technomathematik OPUS4-2029 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Thust, M., ; Kordos, P., ; Schultze, J.W., ; Lüth, H., Capacitive microsensors for biochemical sensing based on porous silicon technology Amsterdam [u.a.] Elsevier 2000 3 Transducers '99 : proceedings of the Tenth International Conference on Solid-State Sensors and Actuators ; 7 - 10 June, 1999, Sendai, Japan / ed.: S. Middelhoek International Conference on Solid State Sensors and Actuators <10, 1999, Sendai, Miyagi-ken> ; Transducers '99 ; (10 : ; 1999.06.07-10 : ; Sendai) 1184 1187 Fachbereich Medizintechnik und Technomathematik OPUS4-2030 Wissenschaftlicher Artikel Schütz, S., ; Hummel, Hans E., ; Schöning, Michael Josef, schoening@fh-aachen.de; Schroth, P., ; Kordos, P., ; Lüth, H., ; Zimmermann, S., ; Schwarz, A., ; Kohl, C.-D., ; Koczan, D., Applications and perspectives of biosensors based on insect olfaction Wunstorf AMA Service 1999 5 Sensor 99 : proceedings / 9th International Fair and Conference for Sensors, Transducers & Systems, May 18 - 20, 1999, Exhibition Centre Nürnberg/Germany Internationale Messe mit Kongreß für Sensoren, Meßaufnehmer & Systeme ; (9, 1999, Nürnberg) 99 104 Fachbereich Medizintechnik und Technomathematik OPUS4-2010 Wissenschaftlicher Artikel Emons, H., ; Glück, O., ; Schöning, Michael Josef, schoening@fh-aachen.de Voltohmmetry - An alternative detection principle at ultrathin metal electrodes in solution Pennington, NJ Electrochemical Society 2001 XVII, 680 S. Chemical and biological sensors and analytical methods : proceedings of the international symposium / Sensor, Physical Electrochemistry, and Organic and Biological Electrochemistry Divisions. Ed.: M. Butler 1-56677-351-2 International Symposium: Chemical and Biological Sensors and Analytical Methods ; (2 : 2001.) 1 3 Fachbereich Medizintechnik und Technomathematik OPUS4-2011 Wissenschaftlicher Artikel Ermelenko, Y., ; Yoshinobu, T., ; Mourzina, Y., ; Schöning, Michael Josef, schoening@fh-aachen.de; Vlasov, Y., ; Iwasaki, H., The hybrid K+/Ca2+ sensor based on laser scanned silicon transducer for multi-component analysis Tokyo Japan Society for Analytical Chemistry 2002 1 CD-ROM Proceedings of ICAS 2001, IUPAC [3rd] International Congress on Analytical Sciences 2001 : August 6 - 10, 2001, Waseda University, Tokyo International Congress on Analytical Sciences <2001, Tokyo> ; International Union of Pure and Applied Chemistry. Pure and applied chemistry ; 73,10. ; Analytical sciences ; 17.2001, special issue i777 i780 Fachbereich Medizintechnik und Technomathematik OPUS4-2012 Wissenschaftlicher Artikel Kurowski, A., ; Schultze, J.W., ; Lüth, H., ; Schöning, Michael Josef, schoening@fh-aachen.de Micro- and nanopatterning of sensor chips by means of macroporous silicon Berlin [u.a.] Springer 2001 3 Transducers '01 Eurosensors XV : digest of technical papers / the 11th International Conference on Solid-State Sensors and Actuators, June 10-14, 2001, Munich, Germany. Ernst Obermeier (Ed.) 3-540-42150-5 Eurosensors (15, 2001, München) ; International Conference on Solid State Sensors and Actuators (11, 2001, München) 640 643 Fachbereich Medizintechnik und Technomathematik OPUS4-2013 Wissenschaftlicher Artikel Mourzina, Y. G., ; Legin, A., ; Vlasov, Y. G., ; Schöning, Michael Josef, schoening@fh-aachen.de; Schubert, J., ; Zander, W., ; Lüth, H., Thin film chemical sensors based on chalcogenide glasses for „electronic tongue" applications Wunstorf AMA Service 2001 4 Sensor 2001 : 10th international conference, May 8 - 10, 2001, Exhibition Centre Nuremberg, Germany ; proceedings Sensor-Kongress ; (10, 2001, Nürnberg) Sensor 2001 Conference ; (10 : ; 2001.05.08-10 : ; Nuremberg) 137 141 Fachbereich Medizintechnik und Technomathematik OPUS4-2014 Wissenschaftlicher Artikel Riemer, A., ; Schroth, P., ; Schütz, S., ; Hummel, Hans E., ; Lüth, H., ; Kohl, C.-D., ; Schöning, Michael Josef, schoening@fh-aachen.de The future of fire detection: Biological sensors? - Die Zukunft der Brandgassensorik: Biologische Sensoren? Köln VdS Schadenverhütung 2000 Getr. Zählung ca. 500 S. Gassensorik in der Brandmeldetechnik : [VdS-Fachtagung, am 15. und 16. November 2000 in Köln] = Gas sensors for fire detection / VdS Schadenverhütung Fachtagung Gassensorik in der Brandmeldetechnik ; (2000, Köln) 1 7 Fachbereich Medizintechnik und Technomathematik OPUS4-2015 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Schroth, P., ; Schütz, S., ; Hummel, Hans E., ; Lüth, H., Connecting an insect antenna to a microchip as a novel type of biosensor [Berlin] [u.a.] VDE-Verl. 2000 5 Proceedings : applications, trends, visions / VDE World Microtechnologies Congress, September 25 - 27, 2000, Expo 2000, Hannover, Germany. Organized by VDE Association for Electrical, Electronic & Information Technologies ....Vol 2. 3-8007-2579-7 MICRO.tec <1, 2000, Hannover>; auch als CD-ROM 411 416 Fachbereich Medizintechnik und Technomathematik OPUS4-2016 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Mourzina, Y. G., ; Schubert, J., ; Zander, W., ; Legin, A., ; Vlasov, Y. G., ; Lüth, H., Can pulsed laser deposition serve as an advanced technique in fabricating chemical sensors? Lyngby, Denmark MIC, Mikroelektronik Centret 2000 1 CD-ROM Proceedings : Copenhagen, Denmark, 27 - 30 August 2000 / [ed.: R. de Reus ...] 87-89935-50-0 Eurosensors ; (14, 2000, København) ; Eurosensors ; (14 : ; 2000.08.27-30 : ; Copenhagen) ; European Conference on Solid-State Transducers ; (14 : ; 2000.08.27-30 : ; Copenhagen) 615 618 Fachbereich Medizintechnik und Technomathematik OPUS4-2017 Wissenschaftlicher Artikel Schroth, P., ; Schöning, Michael Josef, schoening@fh-aachen.de; Lüth, H., ; Weißbecker, B., ; Hummel, Hans E., ; Schütz, S., Extending the capabilities of an antenna/chip biosensor by employing various insect species Lyngby, Denmark MIC, Mikroelektronik Centret 2000 1 CD-ROM Proceedings : Copenhagen, Denmark, 27 - 30 August 2000 / [ed.: R. de Reus ...] 87-89935-50-0 Eurosensors ; (14, 2000, København) ; Eurosensors ; (14 : ; 2000.08.27-30 : ; Copenhagen) ; European Conference on Solid-State Transducers ; (14 : ; 2000.08.27-30 : ; Copenhagen) 27 30 Fachbereich Medizintechnik und Technomathematik OPUS4-2019 Wissenschaftlicher Artikel Mourzina, Yu.G., ; Schöning, Michael Josef, schoening@fh-aachen.de; Schubert, J., ; Zander, W., ; Legin, A., ; Vlasov, Y. G., ; Lüth, H., Thin film microsensors for fast heavy metal analysis Lyngby, Denmark MIC, Mikroelektronik Centret 2000 1 CD-ROM Proceedings : Copenhagen, Denmark, 27 - 30 August 2000 / [ed.: R. de Reus ...] 87-89935-50-0 Eurosensors ; (14, 2000, København) ; Eurosensors ; (14 : ; 2000.08.27-30 : ; Copenhagen) ; European Conference on Solid-State Transducers ; (14 : ; 2000.08.27-30 : ; Copenhagen) 839 840 Fachbereich Medizintechnik und Technomathematik OPUS4-2020 Wissenschaftlicher Artikel Poghossian, Arshak, poghossian@fh-aachen.de; Yoshinobu, T., ; Simonis, A., ; Ecken, H., ; Lüth, H., ; Schöning, Michael Josef, schoening@fh-aachen.de Penicillin detection by means of field-effect based sensors: EnFET, capacitive EIS sensor or LAPS? Lyngby, Denmark MIC, Mikroelektronik Centret 2000 1 CD-ROM Proceedings : Copenhagen, Denmark, 27 - 30 August 2000 / [ed.: R. de Reus ...] 87-89935-50-0 Eurosensors ; (14, 2000, København) ; Eurosensors ; (14 : ; 2000.08.27-30 : ; Copenhagen) ; European Conference on Solid-State Transducers ; (14 : ; 2000.08.27-30 : ; Copenhagen) 27 30 Fachbereich Medizintechnik und Technomathematik OPUS4-2032 Wissenschaftlicher Artikel Thust, M., ; Schroth, P., ; Töpler, A., ; Schöning, Michael Josef, schoening@fh-aachen.de; Müller-Veggian, Mattea, mueller-veggian@opus.fh-aachen.de; Kordos, P., ; Lüth, H., Improving the detection limit of a capacitive sensor by means of a diffusion barrier Bristol [u.a.] Inst. of Physics Publ. 1998 XXVI, 754, I11 S : Ill., graph. Darst. Eurosensors XII : proceedings of the 12th European Conference on Solid-State Transducers and the 9th UK Conference on Sensors and their Applications, Southampton, UK, 13 - 16 September 1998 / ed. by N. M. White ; Vol. 1 0-7503-0595-9 Eurosensors ; (12, 1998, Southampton) ; UK Conference on Sensors and Their Applications ; (9, 1998, Southampton) 507 510 Fachbereich Medizintechnik und Technomathematik OPUS4-2033 Wissenschaftlicher Artikel Doll, T., ; Scharnagl, K., ; Winter, R., ; Bögner, M., ; Eisele, I., ; Ostrik, B., ; Schöning, Michael Josef, schoening@fh-aachen.de Work function gas sensors - reference layers and signal analysis Bristol [u.a.] Inst. of Physics Publ. 1998 XXVI, 754, I11 S : Ill., graph. Darst. Eurosensors XII : proceedings of the 12th European Conference on Solid-State Transducers and the 9th UK Conference on Sensors and their Applications, Southampton, UK, 13 - 16 September 1998 / ed. by N. M. White ; Vol. 1 0-7503-0595-9 Eurosensors ; (12, 1998, Southampton) ; UK Conference on Sensors and Their Applications ; (9, 1998, Southampton) 143 146 Fachbereich Medizintechnik und Technomathematik OPUS4-2034 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Schütz, S., ; Riemer, A., ; Weißbecker, B., ; Steffen, A., ; Kordos, P., ; Lüth, H., ; Hummel, Hans E., A BioFET on the basis of intact insect antennae Warsaw Sensor Lab Sp. 1997 3 Proceedings of the 11th European Conference on Solid-State Transducers / Eurosensors XI, September 21 - 24, 1997, Warsaw, Poland. [Organised by] Warsaw University of Technology. Vol 2. 83-908335-0-6 Eurosensors ; (11, 1997, Warszawa) ; Eurosensors - European Conference on Solid-State Transducers ; (11 : ; 1997.09.21-24 : ; Warsaw) 1461 1464 Fachbereich Medizintechnik und Technomathematik OPUS4-2035 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Weidenbrück, B., ; Thust, M., ; Kordos, P., ; Lüth, H., A silicon-based sensor array with capacitive EIS structures Warsaw Sensor Lab Sp. 1997 3 Proceedings of the 11th European Conference on Solid-State Transducers / Eurosensors XI, September 21 - 24, 1997, Warsaw, Poland. [Organised by] Warsaw University of Technology. Vol 2. 83-908335-0-6 Eurosensors ; (11, 1997, Warszawa) ; Eurosensors - European Conference on Solid-State Transducers ; (11 : ; 1997.09.21-24 : ; Warsaw) 871 874 Fachbereich Medizintechnik und Technomathematik OPUS4-2036 Wissenschaftlicher Artikel Glück, O., ; Schöning, Michael Josef, schoening@fh-aachen.de; Lüth, H., ; Emons, H., ; Hanewinkel, C., ; Schumacher, D., ; Otto, A., Trace metal determination with gold microelectrodes fabricated by silicon technology Warsaw Sensor Lab Sp. 1997 3 Proceedings of the 11th European Conference on Solid-State Transducers / Eurosensors XI, September 21 - 24, 1997, Warsaw, Poland. [Organised by] Warsaw University of Technology. Vol 2. 83-908335-0-6 Eurosensors ; (11, 1997, Warszawa) ; Eurosensors - European Conference on Solid-State Transducers ; (11 : ; 1997.09.21-24 : ; Warsaw) 615 618 Fachbereich Medizintechnik und Technomathematik OPUS4-2037 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Crott, M., ; Ronkel, F., ; Thust, M., ; Schultze, J. W., ; Kordos, P., ; Lüth, H., A capacitive chemical sensor based on porous silicon Gif-sur-Yvette Ed. Frontières 1996 XLIV, 1087, 20 S : Ill., graph. Darst. Proceedings of the 26th European Solid State Device Research Conference : Congress Centre, Bologna, Italy, 9 - 11 September 1996 / ESSDERC '96. Ed. by G. Baccarani 2-86332-196-X ESSDERC ; (26, 1996, Bologna) ; European Solid State Device Research Conference (ESSDERC) 907 910 Fachbereich Medizintechnik und Technomathematik OPUS4-2038 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Beckers, L., ; Schaub, A., ; Zander, W., ; Schubert, J., ; Mesters, S., ; Kordos, P., ; Lüth, H., A novel silicon-based pH sensor prepared by pulsed laser deposition technique Heverlee, Belgium Catholic University Leuven 1996 3 Proceedings of Eurosensors X, the 10th European Conference on Solid-State Transducers, September 8-11, 1996, Leuven, Belgium / [KU Leuven]. Puers, Robert. Vol. 3. 90-803282-1-9 Eurosensors ; (10, 1996, Louvain) Eurosensors, the European Conference on Solid-State Transducers ; (10 : ; 1996.09.08-11 : ; Leuven) 781 784 Fachbereich Medizintechnik und Technomathematik OPUS4-2039 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Schaub, A., ; Zundel, A., ; Beckers, L., ; Schubert, J., ; Zander, W., ; Kordos, P., ; Lüth, H., Pulsed laser deposition as a novel thin film preparation method for silicon-based field effect sensors Gif-sur-Yvette Ed. Frontières 1995 XLV, 847 S : Ill., graph. Darst. Proceedings of the 25th European Solid State Device Research Conference : the Netherlands Congress Centre, The Hague, the Netherlands, 25th - 27th September 1995 / ESSDERC '95. Ed. by H. C. de Graaff 2-86332-182-X ESSDERC ; (25, 1995, 's-Gravenhage) ; European Solid State Device Research Conference (ESSDERC) ; (25 : ; 1995.09.25-27 : ; Den Haag) 601 604 Fachbereich Medizintechnik und Technomathematik OPUS4-2040 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Buß, G., ; Faßbender, F., ; Glück, O., ; Schmitt, G., ; Schultze, J. W., ; Lüth, H., A silicon-based microelectrode array for chemical analysis Amsterdam [u.a.] Elsevier 1998 2 Proceedings of the Seventh International Meeting on Chemical Sensors : 27 - 30 July, 1998, Beijing, P. R. China / ed. Zhi-Gang Zhou International Meeting on Chemical Sensors ; (7, 1998, Beijing) ; International Meeting on Chemical Sensors (IMCS) ; (7 : ; 1998.07.27-30 : ; Beijing) 100 102 Fachbereich Medizintechnik und Technomathematik OPUS4-2041 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Malkoc, Ü., ; Thust, M., ; Steffen, A., ; Kordos, P., ; Lüth, H., Novel electrochemical sensors with structured and porous semiconductor/insulator capacitors Amsterdam [u.a.] Elsevier 1998 2 Proceedings of the Seventh International Meeting on Chemical Sensors : 27 - 30 July, 1998, Beijing, P. R. China / ed. Zhi-Gang Zhou International Meeting on Chemical Sensors ; (7, 1998, Beijing) ; International Meeting on Chemical Sensors (IMCS) ; (7 : ; 1998.07.27-30 : ; Beijing) 885 887 Fachbereich Medizintechnik und Technomathematik OPUS4-1970 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Wang, J., ; Jacobs, M., ; Knobbe, D.-T., ; Muck, A., Amperometric PDMS-glass capillary electrophoresis-based biosensor microchip for catechol and dopamine detection Fukuoka Japan Association of Chemical Sensors 2004 887, 12 S : Ill., graph. Darst. Technical digest of the 10th International Meeting on Chemical Sensors, July 11 - 14, 2004, Tsukuba, Japan / Japan Association of Chemical Sensors Chemical sensors ; 20.2004 Suppl. B. IMCS ; (10, 2004, Tsukuba) ; International Meeting on Chemical Sensors ; (10 : ; 2004.07.11-14 : ; Tsukuba) 566 567 Fachbereich Medizintechnik und Technomathematik OPUS4-1971 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Näther, Niko, naether@fh-aachen.de; Auger, V., ; Poghossian, Arshak, poghossian@fh-aachen.de; Koudelka-Hep, M., Miniaturized flow-through cell with integrated capacitive EIS sensors fabricated at wafer level using Si and Su-8 technologies Fukuoka Japan Association of Chemical Sensors 2004 887, 12 S : Ill., graph. Darst. Technical digest of the 10th International Meeting on Chemical Sensors, July 11 - 14, 2004, Tsukuba, Japan / Japan Association of Chemical Sensors Chemical sensors ; 20.2004 Suppl. B. IMCS ; (10, 2004, Tsukuba) ; International Meeting on Chemical Sensors ; (10 : ; 2004.07.11-14 : ; Tsukuba) 554 555 Fachbereich Medizintechnik und Technomathematik OPUS4-1972 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Wagner, Torsten, torsten.wagner@fh-aachen.de; Wang, C., ; Otto, R., ; Yoshinobu, T., Development of a handheld 16 channel pen-type LAPS for electrochemical sensing Fukuoka Japan Association of Chemical Sensors 2004 887, 12 S : Ill., graph. Darst. Technical digest of the 10th International Meeting on Chemical Sensors, July 11 - 14, 2004, Tsukuba, Japan / Japan Association of Chemical Sensors Chemical sensors ; 20.2004 Suppl. B. IMCS ; (10, 2004, Tsukuba) ; International Meeting on Chemical Sensors ; (10 : ; 2004.07.11-14 : ; Tsukuba) 136 137 Fachbereich Medizintechnik und Technomathematik OPUS4-1973 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Kloock, Joachim P., kloock@fh-aachen.de; Knobbe, D.-T., ; Räde, J., ; Keusgen, M., Silicon field-effect biosensor for cyanide detection Fukuoka Japan Association of Chemical Sensors 2004 887, 12 S : Ill., graph. Darst. Technical digest of the 10th International Meeting on Chemical Sensors, July 11 - 14, 2004, Tsukuba, Japan / Japan Association of Chemical Sensors Chemical sensors ; 20.2004 Suppl. B. IMCS ; (10, 2004, Tsukuba) ; International Meeting on Chemical Sensors ; (10 : ; 2004.07.11-14 : ; Tsukuba) 98 99 Fachbereich Medizintechnik und Technomathematik OPUS4-1974 Wissenschaftlicher Artikel Yoshinobu, T., ; Ermelenko, Y., ; Mourzina, Y., ; Schöning, Michael Josef, schoening@fh-aachen.de; Iwasaki, H., ; Vlasov, Y., Multi-component analysis based on the light-addressable potentiometric sensor (LAPS) Wunstorf AMA Service 2003 3 Proceedings : 11th international conference Sensor 2003; 13 - 15 May 2003, Exhibition Centre Nuremberg, Germany Internationale Messe mit Kongress Sensor <11, 2003, Nürnberg> 141 144 Fachbereich Medizintechnik und Technomathematik OPUS4-1975 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de Silicon-based field-effect structures - From dielectrics to bioelectronics Pennington, NJ Electrochemical Society 2003 IX, 435 S. Dielectrics in emerging technologies : proceedings of the international symposium ; [papers presented at the First International Symposium on Science and Technology of Dielectrics in Emerging Fields held from 27th April to 2nd May 2003 in Paris, France] / sponsoring divisions: Dielectric Science and Technology, Electronics. Ed.: D. Misra. 1-56677-346-6 International Symposium on Science and Technology of Dielectrics in Emerging Fields ; (1, 2003, Paris) 31 37 Fachbereich Medizintechnik und Technomathematik OPUS4-1976 Wissenschaftlicher Artikel Mourzina, Y., ; Yoshinobu, T., ; Ermelenko, Y., ; Furuichi, K., ; Vlasov, Y., ; Schöning, Michael Josef, schoening@fh-aachen.de; Iwasaki, H., Technology of photocurable membranes for ion sensors based on laser scanned semiconductor transducer (LSST) Prague Czech Technical University, Faculty of Electrical Engineering, Department of Measurement 2002 3 Book of abstracts / ed. by J. Saneistr. 80-01-02576-4 Eurosensors ; (16, 2002, Praha) 254 257 Fachbereich Medizintechnik und Technomathematik OPUS4-1977 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Krause, R., ; Block, K., ; Musameh, M., ; Mulchandani, A., ; Wang, J., A dual amperometric / potentiometric FIA-based biosensor for the distinctive detection of organophosphorus pesticides Prague Czech Technical University, Faculty of Electrical Engineering, Department of Measurement 2002 3 Book of abstracts / ed. by J. Saneistr. 80-01-02576-4 Eurosensors ; (16, 2002, Praha) 76 79 Fachbereich Medizintechnik und Technomathematik OPUS4-1978 Wissenschaftlicher Artikel Poghossian, Arshak, poghossian@fh-aachen.de; Berndsen, L., ; Schöning, Michael Josef, schoening@fh-aachen.de Chemical sensor as a physical sensor: ISFET-based flowvelocity, flow-direction and diffusion-coefficient sensor Prague Czech Technical University, Faculty of Electrical Engineering, Department of Measurement 2002 3 Book of abstracts / ed. by J. Saneistr. 80-01-02576-4 Eurosensors ; (16, 2002, Praha) 649 652 Fachbereich Medizintechnik und Technomathematik OPUS4-1979 Wissenschaftlicher Artikel Yoshinobu, T., ; Schöning, Michael Josef, schoening@fh-aachen.de; Otto, R., ; Furuichi, K., ; Mourzina, Yu, ; Ermelenko, Yu, ; Iwasaki, I., Portable light-addressable potentiometric sensor (LAPS) for multisensor applications Prague Czech Technical University, Faculty of Electrical Engineering, Department of Measurement 2002 3 Book of abstracts / ed. by J. Saneistr. 80-01-02576-4 Eurosensors ; (16, 2002, Praha) 898 901 Fachbereich Medizintechnik und Technomathematik OPUS4-1954 Wissenschaftlicher Artikel Yoshinobu, T., ; Iwasaki, H., ; Ui, Y., ; Furuichi, K., ; Ermelenko, Y., ; Mourzina, Y., ; Wagner, Torsten, torsten.wagner@fh-aachen.de; Näther, Niko, naether@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de The light-addressable potentiometric sensor for multi-ion sensing and imaging 2005 3 Methods. 37 (2005), H. 1 1046-2023 99 102 campus http://dx.doi.org/10.1016/j.ymeth.2005.05.020 Fachbereich Medizintechnik und Technomathematik OPUS4-1955 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Yoshinobu, T., ; Schubert, J., ; Steffen, A., ; Lüth, H., Innovative Schichttechniken und Messprinzipien für kapazitive Feldeffektsensoren Berlin [u.a.] VDE-Verl. 2002 421 S : Ill., graph. Darst. Sensoren und Mess-Systeme : Vorträge der 11. ITG/GMA-Fachtagung vom 11. bis 12. März 2002 in Ludwigsburg / Veranst.: Informationstechnische Gesellschaft im VDE (ITG) ... Wiss. Tagungsleitung: C. D. Kohl .... 3-8007-2675-0 Sensoren und Mess-Systeme 2002 151 154 Fachbereich Medizintechnik und Technomathematik OPUS4-1956 Wissenschaftlicher Artikel Kloock, Joachim P., kloock@fh-aachen.de; Mourzina, Y.G., ; Yoshinobu, T., ; Schubert, J., ; Schöning, Michael Josef, schoening@fh-aachen.de Chalkogenidglassensoren für die Schwermetallanalytik Berlin [u.a.] VDE-Verl. 2002 421 S : Ill., graph. Darst. Sensoren und Mess-Systeme : Vorträge der 11. ITG/GMA-Fachtagung vom 11. bis 12. März 2002 in Ludwigsburg / Veranst.: Informationstechnische Gesellschaft im VDE (ITG) ... Wiss. Tagungsleitung: C. D. Kohl .... 3-8007-2675-0 Sensoren und Mess-Systeme 2002 395 398 Fachbereich Medizintechnik und Technomathematik OPUS4-1957 Wissenschaftlicher Artikel Poghossian, Arshak, poghossian@fh-aachen.de; Berndsen, L., ; Lüth, H., ; Schultze, J. W., ; Schöning, Michael Josef, schoening@fh-aachen.de Multi-Parameter-Detektions-System unter dem Einsatz eines einzigen Transducerprinzips sowohl für (bio-)chemische als auch physikalische Sensoren Berlin [u.a.] VDE-Verl. 2002 421 S : Ill., graph. Darst. Sensoren und Mess-Systeme : Vorträge der 11. ITG/GMA-Fachtagung vom 11. bis 12. März 2002 in Ludwigsburg / Veranst.: Informationstechnische Gesellschaft im VDE (ITG) ... Wiss. Tagungsleitung: C. D. Kohl .... 3-8007-2675-0 Sensoren und Mess-Systeme 2002 137 140 Fachbereich Medizintechnik und Technomathematik OPUS4-1958 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de Silicon recognizes biochemical parameters: Microchips for analytical sensor applications 2000 7 American Laboratory. 32 (2000), H. 16 0044-7749 24 31 Fachbereich Medizintechnik und Technomathematik OPUS4-1959 Wissenschaftlicher Artikel Hüllenkremer, B., ; Glück, O., ; Emons, H., ; Lüth, H., ; Schöning, Michael Josef, schoening@fh-aachen.de Voltohmmetrie an polykristallinen Goldelektroden Düsseldorf: VDI-Verl. 2000 1087s.: Ill., graph. Darst. Gesellschaft Mess- und Automatisierungstechnik: Sensoren und Meßsysteme 2000 : Tagung Ludwigsburg, 13. und 14. März 2000 / VDI/VDE-Gesellschaft Meß- und Automatisierungstechnik 3-18-091530-7 VDI-Berichte; 1530 45 54 Fachbereich Medizintechnik und Technomathematik OPUS4-1995 Wissenschaftlicher Artikel Poghossian, Arshak, poghossian@fh-aachen.de; Thust, M., ; Schöning, Michael Josef, schoening@fh-aachen.de; Müller-Veggian, Mattea, mueller-veggian@opus.fh-aachen.de; Kordos, P., ; Lüth, H., Cross-sensitivity of a capacitive penicillin sensor combined with a diffusion barrier 2000 5 Sensors and Actuators B. 68 (2000), H. 1-3 0925-4005 260 265 campus http://dx.doi.org/10.1016/S0925-4005(00)00442-1 Fachbereich Medizintechnik und Technomathematik OPUS4-2006 Wissenschaftlicher Artikel Ermelenko, Y., ; Yoshinobu, T., ; Mourzina, Y., ; Furuichi, K., ; Iwasaki, H., ; Vlasov, Y., ; Schöning, Michael Josef, schoening@fh-aachen.de Technology of photocurable polymeric membranes for integrated LAPS Kasuga, Fukuoka-ken Japan Association of Chemical Sensors 2001 XV, 501 S : Ill., graph. Darst. Proceedings of the 5th East Asian Conference on Chemical Sensors; the 33rd Chemical Sensor Symposium : December 4 - 7, 2001, Huis Ten Bosch, Sasebo-shi, Nagasaki, Japan / Japan Association of Chemical Sensors; the Electrochemical Society of Japan Chemical sensors; 17.2001 Suppl. B; East Asian Conference on Chemical Sensors ; (5, 2001; Nagasaki) 66 68 Fachbereich Medizintechnik und Technomathematik OPUS4-2007 Wissenschaftlicher Artikel Furuichi, K., ; Yoshinobu, T., ; Ermelenko, T., ; Mourzina, Y., ; Iwasaki, H., ; Schöning, Michael Josef, schoening@fh-aachen.de Simultaneous visualization of multiple ions by the chemical imaging sensor Kasuga, Fukuoka-ken Japan Association of Chemical Sensors 2001 XV, 501 S : Ill., graph. Darst. Proceedings of the 5th East Asian Conference on Chemical Sensors; the 33rd Chemical Sensor Symposium : December 4 - 7, 2001, Huis Ten Bosch, Sasebo-shi, Nagasaki, Japan / Japan Association of Chemical Sensors; the Electrochemical Society of Japan Chemical sensors; 17.2001 Suppl. B; East Asian Conference on Chemical Sensors ; (5, 2001; Nagasaki) 399 401 Fachbereich Medizintechnik und Technomathematik OPUS4-2008 Wissenschaftlicher Artikel Poghossian, Arshak, poghossian@fh-aachen.de; Berndsen, L., ; Schultze, J. W., ; Lüth, H., ; Schöning, Michael Josef, schoening@fh-aachen.de „High order" hybrid sensor module based on an identical transducer principle Pennington, NJ Electrochemical Society 2001 XVII, 680 S. Chemical and biological sensors and analytical methods : proceedings of the international symposium / Sensor, Physical Electrochemistry, and Organic and Biological Electrochemistry Divisions. Ed.: M. Butler 1-56677-351-2 International Symposium: Chemical and Biological Sensors and Analytical Methods ; (2 : 2001.) 143 152 Fachbereich Medizintechnik und Technomathematik OPUS4-2009 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Schroth, P., ; Hummel, Hans E., ; Weißbecker, B., ; Lüth, H., ; Schütz, S., Microcsaled living bioelectronic systems - Coupling beetles to silicon transducers Pennington, NJ Electrochemical Society 2001 XVII, 680 S. Chemical and biological sensors and analytical methods : proceedings of the international symposium / Sensor, Physical Electrochemistry, and Organic and Biological Electrochemistry Divisions. Ed.: M. Butler 1-56677-351-2 International Symposium: Chemical and Biological Sensors and Analytical Methods ; (2 : 2001.) 165 173 Fachbereich Medizintechnik und Technomathematik OPUS4-1980 Wissenschaftlicher Artikel Keusgen, M., ; Jünger, M., ; Schöning, Michael Josef, schoening@fh-aachen.de Biosensoric detection of the cysteine sulphoxide alliin Prague Czech Technical University, Faculty of Electrical Engineering, Department of Measurement 2002 3 Book of abstracts / ed. by J. Saneistr. 80-01-02576-4 Eurosensors ; (16, 2002, Praha) 1175 1178 Fachbereich Medizintechnik und Technomathematik OPUS4-1981 Wissenschaftlicher Artikel Schmitt, G., ; Werner, C., ; Schöning, Michael Josef, schoening@fh-aachen.de Microelectrochemical efficiency evaluation of inhibitors for CO2 corrosion of carbon steel under high shear stress gradients Houston, Texas NACE International 2002 10 Corrosion 2002. Conference Proceedings. NACExpo, 57th Annual Conference and Exhibition, Denver, US, Apr 7-11, 2002 Paper 02280 1 11 Fachbereich Medizintechnik und Technomathematik OPUS4-2079 Wissenschaftlicher Artikel Werner, Frederik, f.werner@fh-aachen.de; Wagner, Torsten, torsten.wagner@fh-aachen.de; Miyamoto, Ko-ichiro, ; Yoshinobu, Tatsuo, ; Schöning, Michael Josef, schoening@fh-aachen.de High speed and high resolution chemical imaging based on a new type of OLED-LAPS set-up Light-addressable potentiometric sensors (LAPS) are field-effect-based sensors. A modulated light source is used to define the particular measurement spot to perform spatially resolved measurements of chemical species and to generate chemical images. In this work, an organic-LED (OLED) display has been chosen as a light source. This allows high measurement resolution and miniaturisation of the system. A new developed driving method for the OLED display optimised for LAPS-based measurements is demonstrated. The new method enables to define modulation frequencies between 1 kHz and 16 kHz and hence, reduces the measurement time of a chemical image by a factor of 40 compared to the traditional addressing of an OLED display. Amsterdam Elsevier 2012 4 Sensors and Actuators B: Chemical 175 Part of special issue "Selected Papers presented at Eurosensors XXV" 118 122 10.1016/j.snb.2011.12.102 campus https://doi.org/10.1016/j.snb.2011.12.102 Fachbereich Medizintechnik und Technomathematik OPUS4-2042 Wissenschaftlicher Artikel Schütz, S., ; Schöning, Michael Josef, schoening@fh-aachen.de; Schroth, P., ; Weißbecker, B., ; Kordos, P., ; Lüth, H., ; Hummel, Hans E., An insectbased BioFET as a bioelectronic nose Amsterdam [u.a.] Elsevier 1998 2 Proceedings of the Seventh International Meeting on Chemical Sensors : 27 - 30 July, 1998, Beijing, P. R. China / ed. Zhi-Gang Zhou International Meeting on Chemical Sensors ; (7, 1998, Beijing) ; International Meeting on Chemical Sensors (IMCS) ; (7 : ; 1998.07.27-30 : ; Beijing) 314 316 Fachbereich Medizintechnik und Technomathematik OPUS4-2043 Wissenschaftlicher Artikel Buß, G., ; Ecken, H., ; Winkels, S., ; Schöning, Michael Josef, schoening@fh-aachen.de; Lüth, H., ; Schultze, J. W., Galvanic modifications of multifunctional silicon-based microelectrode arrays Pennington, NJ Electrochemical Society 2000 IX, 434 S. Electrochemical technology applications in electronics : proceedings of the third international symposium / [International Symposium on Electrochemical Technology Applications in Electronics, held during October 20 - 22, 1999, Honolulu, Hawaii]. Electrodeposition Division. Ed.: L. T. Romankiw 1566772575 International Symposium on Electrochemical Technology Applications in Electronics ; (3, 1999, Honolulu, Hawaii) ; Proceedings volume // Electrochemical Society ; 99-34 209 215 Fachbereich Medizintechnik und Technomathematik OPUS4-2185 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Steffen, A., ; Sanke, M. S., ; Müller-Veggian, Mattea, mueller-veggian@opus.fh-aachen.de Kapazitiver Silizium-Sensor als Ph-Transducer für Biosensoranwendungen Frankfurt am Main DECHEMA 1995 1 13. Jahrestagung der Biotechnologen : Wiesbaden 30.05. - 01.06.1995 / Deutsche Gesellschaft für Chemisches Apparatewesen, Chemische Technik und Biotechnologie e.V., Frankfurt am Main. - Bd. 1 Jahrestagung der Biotechnologen <13, 1995, Wiesbaden> ; Deutsche Gesellschaft für Chemisches Apparatewesen, Chemische Technik und Biotechnologie 65 66 Fachbereich Medizintechnik und Technomathematik OPUS4-2904 Wissenschaftlicher Artikel Poghossian, Arshak, poghossian@fh-aachen.de; Abouzar, Maryam H., ; Christiaens, P., ; Williams, O. A., ; Haenen, K., ; Wagner, P., ; Schöning, Michael Josef, schoening@fh-aachen.de Nanocrystalline diamond-based field-effect (bio-)chemical sensor Dresden TUDpress, Verl. der Wissenschaften 2007 343 S. : Ill., graph. Darst. 8. Dresdner Sensor-Symposium : Sensoren für Umwelt, Klima und Sicherheit, Biosensoren und Biosysteme, Sensoren und Sensorsysteme für die Prozesstechnik, Trends in der Sensortechnik, Materialentwicklung für die Sensorik; 8. Dresdner Sensor-Symposium, 10. - 12. Dezember 2007, Dresden / Gerald Gerlach ... (Hg.) 978-3-940046-45-1 Dresdner Sensor-Symposium <8, 2007, Dresden> ; Dresdner Beiträge zur Sensorik ; 29 191 194 Fachbereich Medizintechnik und Technomathematik OPUS4-3050 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Brinkmann, D., ; Rolka, David, d.rolka@fh-aachen.de; Demuth, C., ; Poghossian, Arshak, poghossian@fh-aachen.de CIP (cleaning-in-place) suitable "non-glass" pH sensor based on a Ta2O5-gate EIS structure 2005 6 Sensors and Actuators B: Chemical. 111-112 (2005) 0925-4005 Eurosensors XVIII 2004 - The 18th European Conference on Solid-State Transducers 423 429 campus http://dx.doi.org/10.1016/j.snb.2005.03.053 Fachbereich Medizintechnik und Technomathematik OPUS4-3051 Wissenschaftlicher Artikel Poghossian, Arshak, poghossian@fh-aachen.de; Abouzar, Maryam H., ; Sakkari, M., ; Kassab, T., ; Han, Y., ; Ingebrandt, S., ; Offenhäusser, A., ; Schöning, Michael Josef, schoening@fh-aachen.de Field-effect sensors for monitoring the layer-by-layer adsorption of charged macromolecules 2006 7 Sensors and Actuators B: Chemical. 118 (2006), H. 1-2 0925-4005 Eurosensors XIX - Eurosensors XIX - The 19th European Conference on Solid-State Transducers 163 170 campus http://dx.doi.org/10.1016/j.snb.2006.04.013 Fachbereich Medizintechnik und Technomathematik OPUS4-3052 Wissenschaftlicher Artikel Kloock, Joachim P., kloock@fh-aachen.de; Moreno, Lia, ; Bratov, A., ; Huachupoma, S., ; Xu, J., ; Wagner, Torsten, torsten.wagner@fh-aachen.de; Yoshinobu, T., ; Ermolenko, Y., ; Vlasov, Y. G., ; Schöning, Michael Josef, schoening@fh-aachen.de PLD-prepared cadmium sensors based on chalcogenide glasses —ISFET, LAPS and μISE semiconductor structures 2006 6 Sensors and Actuators B: Chemical. 118 (2006), H. 1-2 0925-4005 Eurosensors XIX - Eurosensors XIX - The 19th European Conference on Solid-State Transducers 149 155 campus http://dx.doi.org/10.1016/j.snb.2006.04.018 Fachbereich Medizintechnik und Technomathematik OPUS4-3053 Wissenschaftlicher Artikel Wagner, Torsten, torsten.wagner@fh-aachen.de; Rao, C., ; Kloock, Joachim P., kloock@fh-aachen.de; Yoshinobu, T., ; Otto, R., ; Keusgen, M., ; Schöning, Michael Josef, schoening@fh-aachen.de "LAPS Card"—A novel chip card-based light-addressable potentiometric sensor (LAPS) 2006 7 Sensors and Actuators B: Chemical. 118 (2006), H. 1-2 0925-4005 Eurosensors XIX - Eurosensors XIX - The 19th European Conference on Solid-State Transducers 33 40 campus http://dx.doi.org/10.1016/j.snb.2006.04.019 Fachbereich Medizintechnik und Technomathematik OPUS4-3054 Wissenschaftlicher Artikel Poghossian, Arshak, poghossian@fh-aachen.de; Abouzar, Maryam H., ; Amberger, F., ; Mayer, D., ; Han, Y., ; Ingebrandt, S., ; Offenhäusser, A., ; Schöning, Michael Josef, schoening@fh-aachen.de Field-effect sensors with charged macromolecules: Characterisation by capacitance-voltage, constant-capacitance, impedance spectroscopy and atomic-force microscopy methods 2007 7 Biosensors and Bioelectronics. 22 (2007), H. 9-10 0956-5663 Selected Papers from the Ninth World Congress On Biosensors. Toronto, Canada 10 - 12 May 2006, Alice X. J . Tang 2100 2107 campus http://dx.doi.org/10.1016/j.bios.2006.09.014 Fachbereich Medizintechnik und Technomathematik OPUS4-3055 Wissenschaftlicher Artikel Ingebrandt, S., ; Han, Y., ; Nakamura, F., ; Poghossian, Arshak, poghossian@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de; Offenhäusser, A., Label-free detection of single nucleotide polymorphisms utilizing the differential transfer function of field-effect transistors 2007 6 Biosensors and Bioelectronics. 22 (2007), H. 12 0956-5663 2834 2840 campus http://dx.doi.org/10.1016/j.bios.2006.11.019 Fachbereich Medizintechnik und Technomathematik OPUS4-3056 Wissenschaftlicher Artikel Poghossian, Arshak, poghossian@fh-aachen.de; Ingebrandt, S., ; Abouzar, Maryam H., ; Schöning, Michael Josef, schoening@fh-aachen.de Label-free detection of charged macromolecules by using a field-effect-based sensor platform: Experiments and possible mechanisms of signal generation 2007 7 Applied Physics A: Materials Science & Processing. 87 (2007), H. 3 0947-8396 Special Issue "From Surface Science to Nanoscale Devices" 517 524 campus http:dx.doi.org/10.1007/s00339-007-3919-7 Fachbereich Medizintechnik und Technomathematik OPUS4-3249 Wissenschaftlicher Artikel Wagner, Torsten, torsten.wagner@fh-aachen.de; Molina, Roberto, ; Yoshinobu, Tatsuo, ; Kloock, Joachim P., kloock@fh-aachen.de; Biselli, Manfred, biselli@fh-aachen.de; Canzoneri, Michele, canzoneri@fh-aachen.de; Schnitzler, Thomas, schnitzler@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de Handheld multi-channel LAPS device as a transducer platform for possible biological and chemical multi-sensor applications 2007 6 Electrochimica Acta. 53 (2007), H. 2 0013-4686 305 311 campus http://dx.doi.org/10.1016/j.electacta.2007.04.006 Fachbereich Chemie und Biotechnologie OPUS4-3468 Wissenschaftlicher Artikel Kloock, Joachim P., kloock@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de; Schumacher, K., ; Rosenkranz, C., ; Schultze, J. W., ; Müller-Veggian, Mattea, mueller-veggian@opus.fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de Funktionsprüfung und Charakterisierung von ionensensitiven Feldeffekttransistoren (ISFETs) auf Waferebene mittels Mikrotropfenzelle für den zukünftigen Einsatz in der Sensorproduktion Berlin VDE-Verl. 2006 630 S. : Ill., graph. Darst. Sensoren und Messsysteme 2006 : Vorträge der 13. ITG/GMA-Fachtagung vom 13. bis 14. März 2006 in Freiburg/Breisgau / Veranst.: Informationstechnische Gesellschaft im VDE (ITG) ; VDE/VDI-Gesellschaft Mess- und Automatisierungstechnik (GMA). Wiss. Tagungsleitung: L. M. Reindl 3-8007-2939-3 Fachtagung Sensoren und Messsysteme <13, 2006, Freiburg, Breisgau> 257 260 Fachbereich Medizintechnik und Technomathematik OPUS4-3448 Wissenschaftlicher Artikel Christiaens, P., ; Abouzar, Maryam H., ; Poghossian, Arshak, poghossian@fh-aachen.de; Wagner, Torsten, torsten.wagner@fh-aachen.de; Bijnens, N., ; Williams, O. A., ; Daenen, M., ; Haenen, K., ; Douthéret, O., ; Haen, J. d´, ; Mekhalif, Z., ; Schöning, Michael Josef, schoening@fh-aachen.de; Wagner, P., pH sensitivity of nanocrystalline diamond films 2007 5 Physica status solidi (A). 204 (2007), H. 9 0031-8965 2925 2930 campus http://dx.doi.org/10.1002/pssa.200776326 Fachbereich Medizintechnik und Technomathematik OPUS4-3453 Wissenschaftlicher Artikel Wagner, Torsten, torsten.wagner@fh-aachen.de; Molina, R., ; Biselli, Manfred, biselli@fh-aachen.de; Canzoneri, Michele, canzoneri@fh-aachen.de; Schnitzler, Thomas, schnitzler@fh-aachen.de; Yoshinobu, Tatsuo, ; Schöning, Michael Josef, schoening@fh-aachen.de A light-addressable potentiometric sensor system for fast, simultaneous and spatial detection of the metabolic activity of biological cells Piscataway IEEE 2007 3 Transducers '07 Eurosensors XXI : digest of technical papers ; the14th International Conference on Solid-State Sensors, Actuators and Microsystems, June 10-14, 2007, Lyon, France / Gilles Delapierre (Ed.) 1-4244-0841-5 Eurosensors 21, 2007, Lyon ; International Conference on Solid-State Sensors, Actuators and Microsystems 14, 2007, Lyon 1107 1110 campus http://dx.doi.org/10.1109/SENSOR.2007.4300328 Fachbereich Chemie und Biotechnologie OPUS4-3455 Wissenschaftlicher Artikel Christiaens, P., ; Abouzar, Maryam H., ; Poghossian, Arshak, poghossian@fh-aachen.de; Wagner, Torsten, torsten.wagner@fh-aachen.de; Bijnens, N., ; Williams, O. A., ; Daenen, M., ; Haenen, K., ; Schöning, Michael Josef, schoening@fh-aachen.de; Wagner, P., Nanocrystalline diamond-based field-effect capacitive pH sensor Piscataway IEEE 2007 3 Transducers '07 Eurosensors XXI : digest of technical papers ; the14th International Conference on Solid-State Sensors, Actuators and Microsystems, June 10-14, 2007, Lyon, France / Gilles Delapierre (Ed.) 1-4244-0841-5 Eurosensors 21, 2007, Lyon ; International Conference on Solid-State Sensors, Actuators and Microsystems 14, 2007, Lyon 1891 1894 campus http://dx.doi.org/10.1109/SENSOR.2007.4300527 Fachbereich Medizintechnik und Technomathematik OPUS4-3440 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de Detection of charged macromolecules by means of field-effect devices (FEDs): possibilities and limitations Amsterdam Elsevier Acad. Press 2008 XXII, 593 S., [4] Bl. : Ill., graph. Darst. Electrochemical sensors, biosensors and their biomedical applications / ed. by Xueji Zhang ... 978-0-12-373738-0 187 212 Fachbereich Medizintechnik und Technomathematik OPUS4-3441 Wissenschaftlicher Artikel Poghossian, Arshak, poghossian@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de Chemical and biological field-effect sensors for liquids - a status report Chichester Wiley 2007 XXXI, 686, XL S. : Ill., graph. Darst. Handbook of biosensors and biochips / ed. Robert S. Marks ... Bd. 1 978-0-470-01905-4 395 412 Fachbereich Medizintechnik und Technomathematik OPUS4-3442 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Kloock, Joachim P., kloock@fh-aachen.de About 20 years of silicon-based thin-film sensors with chalcogenide glass materials for heavy metal analysis: Technological aspects of fabrication and miniaturization 2007 9 Electroanalysis. 19 (2007), H. 19-20 1040-0397 2029 2038 campus http://dx.doi.org/10.1002/elan.200703955 Fachbereich Medizintechnik und Technomathematik OPUS4-3443 Wissenschaftlicher Artikel Wagner, Torsten, torsten.wagner@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de Light-addressable potentiometric sensors (LAPS): recent trends and applications Amsterdam Elsevier 2007 LIV, 974 S. + 1 CD-ROM Electrochemical sensor analysis / edited by S. Alegret ... 978-0-444-53053-0 Wilson & Wilson's comprehensive analytical chemistry ; 49 87 128 Fachbereich Medizintechnik und Technomathematik OPUS4-3444 Wissenschaftlicher Artikel Wagner, Torsten, torsten.wagner@fh-aachen.de; Kloock, Joachim P., kloock@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de Determination of cadmium concentration and pH value in aqueous solutions by means of a handheld light-addressable potentiometric sensor (LAPS) device Amsterdam Elsevier 2007 CD-ROM Electrochemical sensor analysis / edited by S. Alegret ... 978-0-444-53133-9 Wilson & Wilson's comprehensive analytical chemistry ; 49 e35 e44 Fachbereich Medizintechnik und Technomathematik OPUS4-3445 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Abouzar, Maryam H., ; Poghossian, Arshak, poghossian@fh-aachen.de; Han, Yinhua, ; Offenhäusser, Andreas, ; Ingebrandt, Sven, Markierungsfreie DNA-Detektion mit Silizium-Feldeffekt-Sensoren - Messeffekte oder Artefakte? 2007 10 tm - Technisches Messen . 74 (2007), H. 9 0171-8096 466 476 bezahl http://dx.doi.org/10.1524/teme.2007.74.9.466 Fachbereich Medizintechnik und Technomathematik OPUS4-3768 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Abouzar, Maryam H., ; Poghossian, Arshak, poghossian@fh-aachen.de pH and ion sensitivity of a field-effect EIS (electrolyte-insulator-semiconductor) sensor covered with polyelectrolyte multilayers 2009 7 Journal of Solid State Electrochemistry. 13 (2009), H. 1 1433-0768 This manuscript is an invited paper to the special issue on "Solid-state potentiometric sensors" (Guest editor: Johan Bobacka). 115 122 campus http://dx.doi.org/10.1007/s10008-008-0589-0 Fachbereich Medizintechnik und Technomathematik OPUS4-3769 Wissenschaftlicher Artikel Näther, Niko, naether@fh-aachen.de; Emmerich, Rüdiger, ; Berger, Jörg, ; Friedrich, Peter, ; Henkel, Hartmut, ; Schneider, Andreas, ; Schöning, Michael Josef, schoening@fh-aachen.de A novel gas-phase hydrogen peroxide sensor basing on a combined physical/chemical transduction mechanism Warrendale, Pa. Materials Research Soc. 2006 306 S. : Ill., graph. Darst. Nanofunctional materials, nanostructures, and novel devices for biological and chemical detection : November 27 - December 1, 2006, Boston, Massachusetts, USA ; [at the 2006 MRS Fall Meeting]. 978-1-60423-407-7 Materials Research Society symposium proceedings ; 951 ; MRS fall meeting ; (2006.11.27-12.01 : ; Boston, Mass.) 63 68 Fachbereich Medizintechnik und Technomathematik OPUS4-3773 Wissenschaftlicher Artikel Beging, Stefan, beging@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de; Hataihimakul, Sudkanung, ; Busch, H., ; Baldsiefen, G., ; Laube, N., ; Kleinen, L., ; Hosseiny, R., Feldeffektbasierender Ca2+-sensitiver Sensor für den Einsatz im Nativurin zur Bestimmung des Harnsteinbildungsrisikos Düsseldorf VDI-Verl. 2008 956 S. : Ill., graph. Darst. + 1 CD-ROM Sensoren und Messsysteme 2008 : 14. Fachtagung Ludwigsburg, 11. und 12. März 2008 / VDI/VDE-Gesellschaft Mess- und Automatisierungstechnik 978-3-18-092011-5 VDI-Berichte ; 2011 ; Sensoren und Messsysteme 2008, 14. GMA/ITG-Fachtagung, VDI/VDE- Gesellschaft Mess- und Automatisierungstechnik, + CD-ROM, Ludwigsburg, DE, 11.-12. Mar, 2008 775 782 Fachbereich Medizintechnik und Technomathematik OPUS4-3774 Wissenschaftlicher Artikel Näther, Niko, ; Berger, Jörg, ; Emmerich, Rüdiger, ; Friedrich, P., ; Henkel, H., ; Schöning, Michael Josef, schoening@fh-aachen.de H2O2-Konzentrationsbestimmung für die Prozessgasanalytik mittels eines kalorimetrischen Sensoraufbaus Düsseldorf VDI-Verl. 2008 956 S. : Ill., graph. Darst. + 1 CD-ROM Sensoren und Messsysteme 2008 : 14. Fachtagung Ludwigsburg, 11. und 12. März 2008 / VDI/VDE-Gesellschaft Mess- und Automatisierungstechnik 978-3-18-092011-5 VDI-Berichte ; 2011 ; Sensoren und Messsysteme 2008, 14. GMA/ITG-Fachtagung, VDI/VDE- Gesellschaft Mess- und Automatisierungstechnik, + CD-ROM, Ludwigsburg, DE, 11.-12. Mar, 2008 783 792 Fachbereich Medizintechnik und Technomathematik OPUS4-3776 Wissenschaftlicher Artikel Näther, Niko, naether@fh-aachen.de; Berger, Jörg, ; Emmerich, Rüdiger, ; Friedrich, Peter, ; Henkel, Hartmut, ; Schneider, Andreas, ; Schöning, Michael Josef, schoening@fh-aachen.de Entwicklung einer kalorimetrischen H2O2-Gassensoranordnung für die Prozessgaskontrolle Dresden TUDpress, Verl. der Wissenschaften 2007 343 S. : Ill., graph. Darst. 8. Dresdner Sensor-Symposium : Sensoren für Umwelt, Klima und Sicherheit, Biosensoren und Biosysteme, Sensoren und Sensorsysteme für die Prozesstechnik, Trends in der Sensortechnik, Materialentwicklung für die Sensorik; 8. Dresdner Sensor-Symposium, 10. - 12. Dezember 2007, Dresden / Gerald Gerlach ... (Hg.) 978-3-940046-45-1 Dresdner Beiträge zur Sensorik ; 29 261 264 Fachbereich Medizintechnik und Technomathematik OPUS4-3777 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Schütz, S., Der Käfer/Chip-Sensor als bioelektronischer "Schnüffler" Heidelberg Spektrum, Akad. Verl. 2009 XIX, 276 S. : zahlr. Ill., graph. Darst. Bioanalytik für Einsteiger : [Diabetes, Drogen und DNA] / Reinhard Renneberg. Darja Süßbier (Ill.). [Red.: Andreas Held ...] 978-3-8274-1831-9 204 205 Fachbereich Medizintechnik und Technomathematik OPUS4-3765 Wissenschaftlicher Artikel Abouzar, Maryam H., ; Poghossian, Arshak, poghossian@fh-aachen.de; Razavi, A., ; Williams, O. A., ; Bijnens, N., ; Wagner, P., ; Schöning, Michael Josef, schoening@fh-aachen.de Characterisation of capacitive field-effect sensors with a nanocrystalline-diamond film as transducer material for multi-parameter sensing Amsterdam Elsevier 2009 6 Biosensors and Bioelectronics. 24 (2009), H. 5 0956-5663 Selected Papers from the Tenth World Congress on Biosensors Shangai, China, May 14-16, 2008 ; Zeitschrift früher u.d.T. : Biosensors 1298 1304 campus http://dx.doi.org/10.1016/j.bios.2008.07.056 Fachbereich Medizintechnik und Technomathematik OPUS4-3778 Wissenschaftlicher Artikel Gun, Jenny, ; Rizkov, Dan, ; Lev, Ovadia, ; Abouzar, Maryam H., ; Poghossian, Arshak, poghossian@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de Oxygen plasma-treated gold nanoparticle-based field-effect devices as transducer structures for bio-chemical sensing 2008 9 Microchimica Acta. 164 (2008), H. 3-4 1436-5073 395 404 campus http://dx.doi.org/10.1007/s00604-008-0073-7 Fachbereich Medizintechnik und Technomathematik OPUS4-3779 Wissenschaftlicher Artikel Pita, Marcos, ; Krämer, Melina, ; Zouh, Jian, ; Poghossian, Arshak, poghossian@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de; Fernandez, Victor M., ; Katz, Evgeny, Optoelectronic Properties of Nanostructured Ensembles Controlled by Biomolecular Logic Systems 2008 6 ACS Nano. 10 (2008), H. 2 1936-086X 2160 2166 campus http://dx.doi.org/10.1021/nn8004558 Fachbereich Medizintechnik und Technomathematik OPUS4-3780 Wissenschaftlicher Artikel Moreno i Codinachs, Lia, ; Kloock, Joachim P., kloock@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de; Baldi, Antoni, ; Ipatov, Andrey, ; Bratov, Andrey, ; Jimenez-Jorquera, Cecilia, Electronic integrated multisensor tongue applied to grape juice and wine analysis 2008 8 Analyst. 133 (2008) 1364-5528 1440 1448 campus http://dx.doi.org/10.1039/b801228h Fachbereich Medizintechnik und Technomathematik OPUS4-3781 Wissenschaftlicher Artikel Abouzar, Maryam H., ; Poghossian, Arshak, poghossian@fh-aachen.de; Razavi, Arash, ; Besmehn, Astrid, ; Bijnens, Nathalie, ; Williams, Oliver A., ; Haenen, Ken, ; Wagner, Patrick, ; Schöning, Michael Josef, schoening@fh-aachen.de Penicillin detection with nanocrystalline-diamond field-effect sensor 2008 4 physica status solidi (a). 205 (2008), H. 9 1862-6319 Special Issue: Hasselt Diamond Workshop 2008 - SBDD XIII 2141 2145 campus http://dx.doi.org/10.1002/pssa.200879713 Fachbereich Medizintechnik und Technomathematik OPUS4-3782 Wissenschaftlicher Artikel Gun, Jenny, ; Schöning, Michael Josef, schoening@fh-aachen.de; Abouzar, Maryam H., ; Poghossian, Arshak, poghossian@fh-aachen.de; Katz, Evgeny, Field-Effect Nanoparticle-Based Glucose Sensor on a Chip: Amplification Effect of Coimmobilized Redox Species 2008 5 Electroanalysis. 20 (2008), H. 16 1521-4109 1748 1753 campus http://dx.doi.org/10.1002/elan.200804255 Fachbereich Medizintechnik und Technomathematik OPUS4-3783 Wissenschaftlicher Artikel Poghossian, Arshak, poghossian@fh-aachen.de; Abouzar, Maryam H., ; Schöning, Michael Josef, schoening@fh-aachen.de Capacitance-voltage and impedance characteristics of field-effect EIS sensors functionalised with polyelectrolyte multilayers 2008 5 IRBM. 29 (2008), H. 2-3 1959-0318 149 154 campus http://dx.doi.org/10.1016/j.rbmret.2007.11.018 Fachbereich Medizintechnik und Technomathematik OPUS4-3784 Wissenschaftlicher Artikel Turek, M., ; Keusgen, M., ; Poghossian, Arshak, poghossian@fh-aachen.de; Mulchandani, A., ; Wang, J., ; Schöning, Michael Josef, schoening@fh-aachen.de Enzyme-modified electrolyte-insulator-semiconductor sensors 2008 3 Journal of Contemporary Physics. 43 (2008), H. 2 1934-9378 Armenian Academy of Sciences 82 85 campus http://link.springer.com/content/pdf/10.1007%2Fs11958-008-2007-9 Fachbereich Medizintechnik und Technomathematik OPUS4-3785 Wissenschaftlicher Artikel Poghossian, Arshak, poghossian@fh-aachen.de; Abouzar, Maryam H., ; Christiaens, P., ; Williams, O. A., ; Haenen, K., ; Wagner, Patrick, ; Schöning, Michael Josef, schoening@fh-aachen.de Sensing charged macromolecules with nanocrystalline diamond-based field-effect capacitive sensors 2008 4 Journal of Contemporary Physics. 43 (2008), H. 2 1934-9378 Armenian Academy of Sciences 77 81 campus http://dx.doi.org/10.1007/s11958-008-2006-x Fachbereich Medizintechnik und Technomathematik OPUS4-3786 Wissenschaftlicher Artikel Abouzar, Maryam H., ; Schöning, Michael Josef, schoening@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de; Christiaens, P., ; Williams, O. A., ; Wagner, P., ; Haenen, K., Feldeffektsensor auf nanokristalliner Diamantbasis Düsseldorf VDI-Verl. 2008 956 S. : Ill., graph. Darst. + 1 CD-ROM Sensoren und Messsysteme 2008 : 14. Fachtagung Ludwigsburg, 11. und 12. März 2008 / VDI/VDE-Gesellschaft Mess- und Automatisierungstechnik 978-3-18-092011-5 VDI-Berichte ; 2011 ; Sensoren und Messsysteme 2008, 14. GMA/ITG-Fachtagung, VDI/VDE- Gesellschaft Mess- und Automatisierungstechnik, + CD-ROM, Ludwigsburg, DE, 11.-12. Mar, 2008 549 558 Fachbereich Medizintechnik und Technomathematik OPUS4-3787 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de Silicon-based field-effect devices for (bio-)chemical sensing Smolenice, Slovakia 2008 7 International Conference on Advanced Semiconductor Devices and Microsystems, 2008. ASDAM 2008 978-1-4244-2325-5 31 38 campus http://dx.doi.org/10.1109/ASDAM.2008.4743345 Fachbereich Medizintechnik und Technomathematik OPUS4-3883 Wissenschaftlicher Artikel Poghossian, Arshak, poghossian@fh-aachen.de; Ingebrandt, S., ; Offenhäusser, A., ; Schöning, Michael Josef, schoening@fh-aachen.de Field-effect devices for detecting cellular signals Amsterdam Elsevier 2009 7 Seminars in Cell & Developmental Biology. 20 (2009), H. 1 1096-3634 41 48 campus http://dx.doi.org/10.1016/j.semcdb.2009.01.014 Fachbereich Medizintechnik und Technomathematik OPUS4-3884 Wissenschaftlicher Artikel Arida, Hassan, ; Mohsen, Q., ; Schöning, Michael Josef, schoening@fh-aachen.de Microfabrication, characterization and analytical application of a new thin-film silver microsensor 2009 4 Electrochimica Acta. 54 (2009), H. 13 0013-4686 3543 3547 bezahl http://dx.doi.org/10.1016/j.electacta.2008.12.053 Fachbereich Medizintechnik und Technomathematik OPUS4-3885 Wissenschaftlicher Artikel Krämer, Melina, ; Pita, Marcos, ; Zhou, Jian, ; Ornatska, Maryna, ; Poghossian, Arshak, poghossian@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de; Katz, Evgeny, Coupling of Biocomputing Systems with Electronic Chips: Electronic Interface for Transduction of Biochemical Information Washington, DC American Cemical Society 2009 6 Journal of Physical Chemistry C: Nanomaterials and Interfaces. 113 (2009), H. 6 1932-7455 2573 2579 campus http://dx.doi.org/10.1021/jp808320s Fachbereich Medizintechnik und Technomathematik OPUS4-3887 Wissenschaftlicher Artikel Arida, Hassan, ; Turek, Monika, ; Rolka, David, d.rolka@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de A Novel Thin-Film Copper Array Based on an Organic/Inorganic Sensor Hybrid: Microfabrication, Potentiometric Characterization, and Flow-Injection Analysis Application Weinheim Wiley 2009 6 Electroanalysis. 21 (2009), H. 10 1040-0397 1145 1151 campus http://dx.doi.org/10.1002/elan.200804525 Fachbereich Medizintechnik und Technomathematik OPUS4-3888 Wissenschaftlicher Artikel Miyamoto, K., ; Kuwabara, Yohei, ; Kanoh, Shin'ichiro, ; Yoshinobu, Tatsuo, ; Wagner, Torsten, torsten.wagner@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de Chemical image scanner based on FDM-LAPS Amsterdam Elsevier 2009 5 Sensors and Actuators B: Chemical. 137 (2009), H. 2 0925-4005 533 538 bezahl http://dx.doi.org/10.1016/j.snb.2008.12.008 Fachbereich Medizintechnik und Technomathematik OPUS4-3862 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Doll, Theodor, ; Wagner, Patrick, Preface / Doll, Theodor ; Wagner, Patrick ; Schöning, Michael J. 2009 1 physica status solidi (a) . 206 (2009), H. 3 1862-6319 Special Issue: Engineering of Functional Interfaces (EnFI 08) 389 390 campus http://dx.doi.org/10.1002/pssa.200880488 Fachbereich Medizintechnik und Technomathematik OPUS4-3863 Wissenschaftlicher Artikel Moreno i Codinachs, L., ; Birkenstock, C., ; Garma, T., ; Zierold, R., ; Bachmann, J., ; Nielsch, K., ; Schöning, Michael Josef, schoening@fh-aachen.de; Fontcuberta i Morral, A., A micron-sized nanoporous multifunction sensing device Weinheim Wiley 2009 6 physica status solidi (a) . 206 (2009), H. 3 1862-6319 Special Issue: Engineering of Functional Interfaces (EnFI 08) 435 441 campus http://dx.doi.org/10.1002/pssa.200880472 Fachbereich Medizintechnik und Technomathematik OPUS4-3865 Wissenschaftlicher Artikel Siqueira, José R. Jr., ; Abouzar, Maryam H., ; Bäcker, Matthias, baecker@fh-aachen.de; Zucolotto, Valtencir, ; Poghossian, Arshak, poghossian@fh-aachen.de; Oliveira, Osvaldo N. Jr., ; Schöning, Michael Josef, schoening@fh-aachen.de Carbon nanotubes in nanostructured films: Potential application as amperometric and potentiometric field-effect (bio-)chemical sensors Weinheim Wiley 2009 5 physica status solidi (a) . 206 (2009), H. 3 1862-6319 Special Issue: Engineering of Functional Interfaces (EnFI 08) 462 467 campus http://dx.doi.org/10.1002/pssa.200880483 Fachbereich Medizintechnik und Technomathematik OPUS4-3967 Wissenschaftlicher Artikel Siqueira, José R. Jr., ; Bäcker, Matthias, baecker@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de; Zucolotto, Valtencir, ; Oliveira, Osvaldo N. Jr., ; Schöning, Michael Josef, schoening@fh-aachen.de Associating biosensing properties with the morphological structure of multilayers containing carbon nanotubes on field-effect devices 2010 5 Physica status solidi (a). 207 (2010), H. 4 1862-6300 Special Issue: Engineering of Functional Interfaces EnFI 2009 781 786 campus http://dx.doi.org/10.1002/pssa.200983301 Fachbereich Medizintechnik und Technomathematik OPUS4-3970 Wissenschaftlicher Artikel Buniatyan, Vahe V., ; Abouzar, Maryam H., ; Martirosyan, Norayr W., ; Schubert, Jürgen, ; Gevorgian, Spartak, ; Schöning, Michael Josef, schoening@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de pH-sensitive properties of barium strontium titanate (BST) thin films prepared by pulsed laser deposition technique 2010 6 Physica Status Solidi (A). 207 (2010), H. 4 1862-6300 Special Issue: Engineering of Functional Interfaces EnFI 2009 824 830 campus http://dx.doi.org/10.1002/pssa.200983310 Fachbereich Medizintechnik und Technomathematik OPUS4-3972 Wissenschaftlicher Artikel Abouzar, Maryam H., ; Poghossian, Arshak, poghossian@fh-aachen.de; Siqueira, José R. Jr., ; Oliveira, Osvaldo N. Jr., ; Moritz, Werner, ; Schöning, Michael Josef, schoening@fh-aachen.de Capacitive electrolyte-insulator-semiconductor structures functionalised with a polyelectrolyte/enzyme multilayer: New strategy for enhanced field-effect biosensing 2010 6 Physica Status Solidi (A). 207 (2010), H. 4 1862-6300 Special Issue: Engineering of Functional Interfaces EnFI 2009 884 890 campus http://dx.doi.org/10.1002/pssa.200983317 Fachbereich Medizintechnik und Technomathematik OPUS4-3973 Wissenschaftlicher Artikel Reisert, Steffen, reisert@fh-aachen.de; Henkel, Hartmut, ; Schneider, Andreas, ; Schäfer, Daniel, ; Friedrich, Peter, ; Berger, Jörg, ; Schöning, Michael Josef, schoening@fh-aachen.de Development of a handheld sensor system for the online measurement of hydrogen peroxide in aseptic filling systems 2010 5 Physica Status Solidi (A). 207 (2010), H. 4 1862-6300 Special Issue: Engineering of Functional Interfaces EnFI 2009 913 918 campus http://dx.doi.org/10.1002/pssa.200983304 Fachbereich Medizintechnik und Technomathematik OPUS4-3974 Wissenschaftlicher Artikel Beging, Stefan, beging@fh-aachen.de; Mlynek, Daniela, ; Hataihimakul, Sudkanung, ; Poghossian, Arshak, poghossian@fh-aachen.de; Baldsiefen, Gerhard, ; Busch, Heinz, ; Laube, Norbert, ; Kleinen, Lisa, ; Schöning, Michael Josef, schoening@fh-aachen.de Field-effect calcium sensor for the determination of the risk of urinary stone formation 2010 5 Sensors and Actuators B: Chemical. 144 (2010), H. 2 22nd International Conference on Eurosensors - Dresden, Germany, 7-10 September 2008 ; Eurosensors ; (22, 2008, Dresden) 374 379 campus http://dx.doi.org/10.1016/j.snb.2008.12.012 Fachbereich Medizintechnik und Technomathematik OPUS4-3975 Wissenschaftlicher Artikel Miyamoto, Ko-ichiro, ; Sugawara, Yuri, ; Kanoh, Shin´ichiro, ; Yoshinobu, Tatsuo, ; Wagner, Torsten, torsten.wagner@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de Image correction method for the chemical imaging sensor 2010 4 Sensors and Actuators B: Chemical. 144 (2010), H. 2 22nd International Conference on Eurosensors - Dresden, Germany, 7-10 September 2008 ; Eurosensors ; (22, 2008, Dresden) 344 348 campus http://dx.doi.org/10.1016/j.snb.2008.10.069 Fachbereich Medizintechnik und Technomathematik OPUS4-3976 Wissenschaftlicher Artikel Bäcker, Matthias, baecker@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de; Abouzar, Maryam H., ; Wenmackers, Sylvia, ; Janssens, Stoffel D., ; Haenen, Ken, ; Wagner, Patrick, ; Schöning, Michael Josef, schoening@fh-aachen.de Capacitive field-effect (bio-)chemical sensors based on nanocrystalline diamond films 2010 5 Diamond Electronics and Bioelectronics — Fundamentals to Applications III, edited by P. Bergonzo, [u.a.] MRS Proceedings Volume 1203 paper 1203-J17-31 ; Mater. Res. Soc. Sympos. Proc. Vol 1203 (2010) ; Materials Research Society 1 6 bezahl http://dx.doi.org/10.1557/PROC-1203-J17-31 Fachbereich Medizintechnik und Technomathematik OPUS4-3990 Wissenschaftlicher Artikel Gasparyan, F. V., ; Poghossian, Arshak, poghossian@fh-aachen.de; Vitusevich, S. A., ; Petrychuk, M. V., ; Sydoruk, V. A., ; Surmalyan, A. V., ; Siqueira, J. R., ; Oliveira, O. N., ; Offenhäusser, A., ; Schöning, Michael Josef, schoening@fh-aachen.de Low Frequency Noise In Electrolyte-Gate Field-Effect Devices Functionalized With Dendrimer/Carbon-Nanotube Multilayers Melville, NY American Inst. of Physics 2009 XX, 664 S : Ill., graph. Darst. Noise and fluctuations : 20th International Conference on Noise and Fluctuations, ICNF 2009, Pisa, Italy, 14 - 19 June 2009 / ed. Massimo Macucci; Giovanni Basso 9780735406650 AIP conference proceedings ; 1129 ; International Conference on Noise and Fluctuations ; (20, 2009, Pisa) 133 136 bezahl http://dx.doi.org/10.1063/1.3140412 Fachbereich Medizintechnik und Technomathematik OPUS4-3991 Wissenschaftlicher Artikel Buniatyan, Vahe V., ; Matirosyan, N., ; Abouzar, Maryam H., ; Schubert, J., ; Zander, W., ; Gevorgian, S., ; Schöning, Michael Josef, schoening@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de Capacitive field-effect pH sensor based on an electrolyte-ferroelectric-insulator-semiconductor structure Wunstorf AMA Service 2009 5 SENSOR 2009 : : 14th International Conference on Sensors, Technologies, Electronics and Applications; Nürnberg, Germany, 26 - 28 May 2009; proceedings; [part of] Sensor + Test Conference 2009 / AMA, Fachverband für Sensorik e.V 9783981099355 AMA, Fachverband für Sensorik ; Sensor International Conference ; (14 : ; 2009.05.26-28 : ; Nürnberg) 317 322 Fachbereich Medizintechnik und Technomathematik OPUS4-3952 Wissenschaftlicher Artikel Siqueira, Jose R., ; Maki, Rafael M., ; Paulovich, Fernando V., ; Werner, Frederik, f.werner@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de; Oliveira, Maria C. F. de, ; Zucolotto, Valtencir, ; Oliveira, Osvaldo N. Jr., ; Schöning, Michael Josef, schoening@fh-aachen.de Use of Information Visualization Methods Eliminating Cross Talk in Multiple Sensing Units Investigated for a Light-Addressable Potentiometric Sensor 2010 4 Analytical Chemistry (2010) 0003-2700 61 65 campus http://dx..doi.org/10.1021/ac9024076 Fachbereich Medizintechnik und Technomathematik OPUS4-3953 Wissenschaftlicher Artikel Siqueira, José R. Jr., ; Abouzar, Maryam H., ; Poghossian, Arshak, poghossian@fh-aachen.de; Zucolotto, Valtencir, ; Oliveira, Osvaldo N. Jr., ; Schöning, Michael Josef, schoening@fh-aachen.de Penicillin biosensor based on a capacitive field-effect structure functionalized with a dendrimer/carbon nanotube multilayer 2009 4 Biosensors and Bioelectronics. 25 (2009), H. 2 0956-5663 497 501 campus http://dx.doi.org/10.1016/j.bios.2009.07.007 Fachbereich Medizintechnik und Technomathematik OPUS4-3977 Wissenschaftlicher Artikel Kirchner, Patrick, kirchner@fh-aachen.de; Li, B., ; Spelthahn, H., ; Henkel, H., ; Schneider, A., ; Kolstad, J., ; Friedrich, P., ; Schöning, Michael Josef, schoening@fh-aachen.de Realisierung eines miniaturisierten Gassensors in Chiptechnologie basierend auf einer Dünnschicht-Thermosäule zur H2O2-Detektion in aseptischen Abfüllanlagen Dresden TUDpress 2009 351 S. : Ill., graph. Darst. 9. Dresdner Sensor-Symposium : Dresden, 07.-09. Dezember 2009 / Gerlach, Gerald ; Hauptmann, Peter [Hrsg.] 978-3-941298-44-6 Dresdner Sensor-Symposium ; (9, 2009, Dresden) 293 296 Fachbereich Medizintechnik und Technomathematik OPUS4-3978 Wissenschaftlicher Artikel Reisert, Steffen, reisert@fh-aachen.de; Henkel, H., ; Schneider, A., ; Schäfer, D., ; Friedrich, P., ; Berger, J., ; Schöning, Michael Josef, schoening@fh-aachen.de Entwicklung eines Handheld-Sensorsystems für die „On-line"-Messung der H2O2-Konzentration in aseptischen Entkeimungsprozessen Dresden TUDpress 2009 351 S. : Ill., graph. Darst. 9. Dresdner Sensor-Symposium : Dresden, 07.-09. Dezember 2009 / Gerlach, Gerald ; Hauptmann, Peter [Hrsg.] 978-3-941298-44-6 Dresdner Sensor-Symposium ; (9, 2009, Dresden) 285 288 Fachbereich Medizintechnik und Technomathematik OPUS4-3981 Wissenschaftlicher Artikel Bäcker, Matthias, ; Kowollik, Silvia, ; Schnitzler, Thomas, schnitzler@fh-aachen.de; Wang, J., ; Poghossian, Arshak, poghossian@fh-aachen.de; Zang, Werner, zang@fh-aachen.de; Biselli, Manfred, biselli@fh-aachen.de; Wagner, P., ; Schöning, Michael Josef, schoening@fh-aachen.de Entwicklung eines festkörperbasierten Sensorsystems für die Bioprozessautomatisierung Dresden TUDpress 2009 351 S. : Ill., graph. Darst. 9. Dresdner Sensor-Symposium : Dresden, 07.-09. Dezember 2009 / Gerlach, Gerald ; Hauptmann, Peter [Hrsg.] 978-3-941298-44-6 Dresdner Sensor-Symposium ; (9, 2009, Dresden) 197 200 Fachbereich Medizintechnik und Technomathematik OPUS4-3982 Wissenschaftlicher Artikel Werner, Frederik, f.werner@fh-aachen.de; Groebel, Simone, groebel@fh-aachen.de; Schuhmacher, K., ; Spelthahn, Heiko, spelthahn@fh-aachen.de; Wagner, Torsten, torsten.wagner@fh-aachen.de; Selmer, Thorsten, selmer@fh-aachen.de; Baumann, Marcus, rektor@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de Bestimmung der metabolischen Aktivität von Mikroorganismen während des Biogasbildungsprozesses Dresden TUDpress 2009 351 S. : Ill., graph. Darst. 9. Dresdner Sensor-Symposium : Dresden, 07.-09. Dezember 2009 / Gerlach, Gerald ; Hauptmann, Peter [Hrsg.] 978-3-941298-44-6 Dresdner Sensor-Symposium ; (9, 2009, Dresden) 201 204 Fachbereich Chemie und Biotechnologie OPUS4-3984 Wissenschaftlicher Artikel Wagner, Torsten, torsten.wagner@fh-aachen.de; Werner, Frederik, f.werner@fh-aachen.de; Miyamoto, K., ; Schöning, Michael Josef, schoening@fh-aachen.de; Yoshinobu, T., A high-density multi-point LAPS set-up using a VCSEL array and FPGA control Amsterdam Elsevier 2009 3 Procedia Chemistry. 1 (2009), H. 1 1876-6196 Proceedings of the Eurosensors XXIII conference ; Eurosensors 23 1483 1486 campus http://dx.doi.org/10.1016/j.proche.2009.07.370 Fachbereich Medizintechnik und Technomathematik OPUS4-3986 Wissenschaftlicher Artikel Poghossian, Arshak, poghossian@fh-aachen.de; Wagner, Holger, ; Schöning, Michael Josef, schoening@fh-aachen.de Functional testing and characterisation of (bio-)chemical sensors on wafer level 2009 3 Procedia Chemistry. 1 (2009), H. 1 1876-6196 Proceedings of the Eurosensors XXIII conference ; Eurosensors 23 835 838 campus http://dx.doi.org/10.1016/j.proche.2009.07.208 Fachbereich Medizintechnik und Technomathematik OPUS4-3987 Wissenschaftlicher Artikel Miyamoto, Ko-ichiro, ; Wagner, Torsten, torsten.wagner@fh-aachen.de; Mimura, Shuhei, ; Kanoh, Shin`ichiro, ; Yoshinobu, Tatsuo, ; Schöning, Michael Josef, schoening@fh-aachen.de Constant-phase-mode operation of the light-addressable potentiometric sensor Amsterdam Elsevier 2009 3 Procedia Chemistry. 1 (2009), H. 1 1876-6196 Proceedings of the Eurosensors XXIII conference ; Eurosensors 23 1487 1490 campus http://dx.doi.org/10.1016/j.proche.2009.07.371 Fachbereich Medizintechnik und Technomathematik OPUS4-3988 Wissenschaftlicher Artikel Kirchner, Patrick, kirchner@fh-aachen.de; Li, B., ; Spelthahn, H., ; Henkel, H., ; Friedrich, P., ; Kolstad, J., ; Keusgen, M., ; Schöning, Michael Josef, schoening@fh-aachen.de Thin-film calorimetric H2O2 gas sensor for the validation of germicidal effectivity in aseptic filling processes 2009 3 Procedia Chemistry. 1 (2009), H. 1 1876-6196 Proceedings of the Eurosensors XXIII conference ; Eurosensors 23 983 986 campus http://dx.doi.org/10.1016/j.proche.2009.07.245 Fachbereich Medizintechnik und Technomathematik OPUS4-3989 Wissenschaftlicher Artikel Abouzar, Maryam H., ; Ingebrandt, S., ; Poghossian, Arshak, poghossian@fh-aachen.de; Zhang, Y., ; Vu, X. T., ; Moritz, W., ; Schöning, Michael Josef, schoening@fh-aachen.de Nanoplate field-effect capacitive (bio-)chemical sensor array based on SOI structure 2009 3 Procedia Chemistry. 1 (2009), H. 1 1876-6196 Proceedings of the Eurosensors XXIII conference ; Eurosensors 23 670 673 campus http://dx.doi.org/10.1016/j.proche.2009.07.167 Fachbereich Medizintechnik und Technomathematik OPUS4-3954 Wissenschaftlicher Artikel Poghossian, Arshak, poghossian@fh-aachen.de; Abouzar, Maryam H., ; Razavi, A., ; Bäcker, Matthias, baecker@fh-aachen.de; Bijnens, N., ; Williams, O. A., ; Haenen, K., ; Moritz, W., ; Wagner, P., ; Schöning, Michael Josef, schoening@fh-aachen.de Nanocrystalline-diamond thin films with high pH and penicillin sensitivity prepared on a capacitive Si-SiO2 structure 2009 4 Electrochimica Acta. 54 (2009), H. 25 0013-4686 5981 5985 campus http://dx.doi.org/10.1016/j.electacta.2009.03.011 Fachbereich Medizintechnik und Technomathematik OPUS4-3955 Wissenschaftlicher Artikel Spelthahn, Heiko, spelthahn@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de Self-aligned nanogaps and nanochannels via conventional photolithography and pattern-size reduction technique 2009 4 Electrochimica Acta. 54 (2009), H. 25 Sp. Iss. SI 0013-4686 6010 6014 campus http://dx.doi.org/10.1016/j.electacta.2009.03.029 Fachbereich Medizintechnik und Technomathematik OPUS4-3956 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Turek, M., ; Heiden, W., ; Riesen, A., ; Chhabda, T. A., ; Schubert, J., ; Krüger, P., ; Keusgen, M., Artificial intelligence/fuzzy logic method for analysis of combined signals from heavy metal chemical sensors New York Elsevier 2009 6 Electrochimica Acta. 54 (2009), H. 25 Sp. Iss. SI 0013-4686 6082 6088 bezahl http://dx.doi.org/10.1016/j.electacta.2009.03.035 Fachbereich Medizintechnik und Technomathematik OPUS4-3958 Wissenschaftlicher Artikel Bäcker, Matthias, baecker@fh-aachen.de; Beging, Stefan, beging@fh-aachen.de; Biselli, Manfred, biselli@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de; Wang, J., ; Zang, Werner, zang@fh-aachen.de; Wagner, Patrick, ; Schöning, Michael Josef, schoening@fh-aachen.de Concept for a solid-state multi-parameter sensor system for cell-culture monitoring Amsterdam Elsevier 2009 5 Electrochimica Acta. 54 (2009), H. 25 Sp. Iss. SI 0013-4686 6107 6112 campus http://dx.doi.org/10.1016/j.electacta.2009.02.091 Fachbereich Chemie und Biotechnologie OPUS4-4042 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de Silicon-based field-effect devices with nanostructured surfaces for bio-/chemical sensing 2009 2 Semiconductor micro- and nanoelectronics : Proceedings of the Seventh International Conference , Tsakhcadzor, Armenia July 3-5 2009 51 53 Fachbereich Medizintechnik und Technomathematik OPUS4-4043 Wissenschaftlicher Artikel Buniatyan, V. V., ; Matirosyan, N. W., ; Abouzar, Maryam H., ; Schöning, Michael Josef, schoening@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de; Schubert, J., ; Khachatryan, V. R., ; Soukiassyan, G. R., (Ba,Sr)TiO3 based electrolyte-insulator-semiconductor pHsensors: comparitive study 2009 3 Semiconductor micro- and nanoelectronics : Proceedings of the Seventh International Conference , Tsakhcadzor, Armenia July 3-5 2009 71 74 Fachbereich Medizintechnik und Technomathematik OPUS4-4044 Wissenschaftlicher Artikel Abouzar, Maryam H., ; Ingebrandt, S., ; Poghossian, Arshak, poghossian@fh-aachen.de; Zhang, Y., ; Moritz, W., ; Schöning, Michael Josef, schoening@fh-aachen.de Field-effect nanoplate capacitive pH sensor based on SOI structure 2009 3 Semiconductor micro- and nanoelectronics : Proceedings of the Seventh International Conference , Tsakhcadzor, Armenia July 3-5 2009 55 58 Fachbereich Medizintechnik und Technomathematik OPUS4-4272 Wissenschaftlicher Artikel Wagner, Torsten, torsten.wagner@fh-aachen.de; Werner, Frederik, f.werner@fh-aachen.de; Miyamoto, Ko-Ichiro, ; Schöning, Michael Josef, schoening@fh-aachen.de; Yoshinobu, Tatsuo, Development and characterisation of a compact light-addressable potentiometric sensor (LAPS) based on the digital light processing (DLP) technology for flexible chemical imaging 2012 5 Sensors and Actuators B: Chemical. 170 (2012) 0925-4005 Eurosensors XXIV, 2010 34 39 campus http://dx.doi.org/10.1016/j.snb.2010.12.003 Fachbereich Medizintechnik und Technomathematik OPUS4-4273 Wissenschaftlicher Artikel Werner, Frederik, f.werner@fh-aachen.de; Schusser, Sebastian, schusser@fh-aachen.de; Spalthahn, Heiko, ; Wagner, Torsten, torsten.wagner@fh-aachen.de; Yoshinobu, Tatsuo, ; Schöning, Michael Josef, schoening@fh-aachen.de Field-programmable gate array based controller for multi spot light-addressable potentiometric sensors with integrated signal correction mode Amsterdam Elsevier 2011 4 Electrochimica Acta. 56 (2011), H. 26 0013-4686 9656 9660 campus http://dx.doi.org/10.1016/j.electacta.2011.03.012 Fachbereich Medizintechnik und Technomathematik OPUS4-4240 Wissenschaftlicher Artikel Abouzar, Maryam H., ; Pedraza, A. M., ; Schöning, Michael Josef, schoening@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de Label-free DNA hybridization and denaturation detection by means of field-effect nanoplate SOI capacitors functionalized with gold nanoparticles 2010 3 Procedia Engineering. 5 (2010) 1877-7058 Proc. Eurosensors XXIV, September 5-8, 2010, Linz, Austria 918 921 campus http://dx.doi.org/10.1016/j.proeng.2010.09.259 Fachbereich Medizintechnik und Technomathematik OPUS4-4255 Wissenschaftlicher Artikel Abouzar, Maryam H., ; Poghossian, Arshak, poghossian@fh-aachen.de; Pedraza, A. M., ; Gandhi, D., ; Ingebrandt, S., ; Moritz, W., ; Schöning, Michael Josef, schoening@fh-aachen.de An array of field-effect nanoplate SOI capacitors for (bio-)chemical sensing Amsterdam Elsevier 2011 5 Biosensors and Bioelectronics. 26 (2011), H. 6 0956-5663 3023 3028 campus http://dx.doi.org/10.1016/j.bios.2010.12.006 Fachbereich Medizintechnik und Technomathematik OPUS4-4371 Wissenschaftlicher Artikel Miyamoto, Ko-ichiro, ; Wagner, Torsten, torsten.wagner@fh-aachen.de; Yoshinobu, Tatsuo, ; Kanoh, Shin`ichiro, ; Schöning, Michael Josef, schoening@fh-aachen.de Phase-mode LAPS and its application to chemical imaging Amsterdam Elsevier 2011 4 Sensors and Actuators B: Chemical. 154 (2011), H. 1 1873-3077 28 32 campus http://dx.doi.org/10.1016/j.snb.2009.12.022 Fachbereich Medizintechnik und Technomathematik OPUS4-4372 Wissenschaftlicher Artikel Miyamoto, Ko-ichiro, ; Yoshida, Midori, ; Sakai, Taito, ; Matsuzaka, Atsushi, ; Wagner, Torsten, torsten.wagner@fh-aachen.de; Kanoh, Sanoh, ; Yoshinobu, Tatsuo, ; Schöning, Michael Josef, schoening@fh-aachen.de Differential setup of light-addressable potentiometric sensor with an enzyme reactor in a flow channel Bristol Japan Society of Applied Physics 2011 NaN Japanese Journal of Applied Physics. 50 (2011) 0021-4922 04DL08-1 04DL08-5 bezahl http://dx.doi.org/10.1143/JJAP.50.04DL08 Fachbereich Medizintechnik und Technomathematik OPUS4-4373 Wissenschaftlicher Artikel Gasparyan, F.V., ; Vitusevich, S.A., ; Offenhäusser, A., ; Schöning, Michael Josef, schoening@fh-aachen.de Modified charge fluctuation noise model for electrolyte-insulator-semiconductor devices Singapur World Scientific Publ. 2011 9 Modern Physics Letters B (MPLB). 25 (2011), H. 11 0217-9849 831 840 bezahl http://dx.doi.org/10.1142/S0217984911026103 Fachbereich Medizintechnik und Technomathematik OPUS4-4374 Wissenschaftlicher Artikel Grinsven, B. van, ; Bon, N. vanden, ; Grieten, L., ; Murib, M., ; Janssen, S. D., ; Haenen, K., ; Schneider, E., ; Ingebrandt, E., ; Schöning, Michael Josef, schoening@fh-aachen.de; Vermeeren, V., ; Ameloot, M., ; Michiels, L., ; Thoelen, R., ; Ceuninck, W. de, ; Wagner, P., Rapid assessment of the stability of DNA duplexes by impedimetric real-time monitoring of chemically induced denaturation Cambridge RSC 2011 7 Lab on a Chip. 11 (2011), H. 9 1473-0197 1656 1663 bezahl http://dx.doi.org/10.1039/C1LC20027E Fachbereich Medizintechnik und Technomathematik OPUS4-4375 Wissenschaftlicher Artikel Gun, Jenny, ; Gutkin, Vitaly, ; Lev, Ovadia, ; Boyen, Hans-Gerd, ; Saitner, Marc, ; Wagner, Patrick, ; Olieslaeger, Marc D´, ; Abouzar, Maryam H., ; Poghossian, Arshak, poghossian@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de Tracing gold nanoparticle charge by electrolyte-insulator-semiconductor devices Washington, DC American Cemical Society 2011 6 Journal of Physical Chemistry C. 115 (2011), H. 11 1932-7455 4439 4445 campus http://dx.doi.org/10.1021/jp109886s Fachbereich Medizintechnik und Technomathematik OPUS4-4376 Wissenschaftlicher Artikel Spelthahn, Heiko, spelthahn@fh-aachen.de; Schaffrath, Sophie, ; Coppe, Thomas, ; Rufi, Frederic, ; Schöning, Michael Josef, schoening@fh-aachen.de Development of an electrolyte-insulator-semiconductor (EIS) based capacitive heavy metal sensor for the detection of Pb2+ und Cd2+ ions 2010 4 Physica status solidi (a) : applications and material science. 207 (2010), H. 4 1862-6300 Special Issue: Engineering of Functional Interfaces EnFI 2009 930 934 campus http://dx.doi.org/10.1002/pssa.200983306 Fachbereich Medizintechnik und Technomathematik OPUS4-4377 Wissenschaftlicher Artikel Miyamoto, Ko-ichiro, ; Wagner, Torsten, torsten.wagner@fh-aachen.de; Yoshinobu, Tatsuo, ; Kanoh, Shin`ichiro, ; Schöning, Michael Josef, schoening@fh-aachen.de Phase-mode operation of FDM-LAPS Stevenson Ranch, Calif. American Scientific Publishers 2011 3 Sensor letters 9 1546-1971 2 691 694 bezahl http://dx.doi.org/10.1166/sl.2011.1593 Fachbereich Medizintechnik und Technomathematik OPUS4-4378 Wissenschaftlicher Artikel Bäcker, Matthias, baecker@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de; Schnitzler, Thomas, schnitzler@fh-aachen.de; Biselli, Manfred, biselli@fh-aachen.de; Zang, Werner, zang@fh-aachen.de; Wagner, P., Entwicklung eines modularen festkörperbasierten Sensorsystems für die Überwachung von Zellkulturfermentationen Berlin VDE Verlag 2010 1 CD-ROM Sensoren und Messsysteme 2010 [Elektronische Ressource] : Vorträge der 15. ITG/GMA-Fachtagung vom 18. bis 19. Mai 2010 in Nürnberg / Informationstechnische Gesellschaft im VDE (ITG); VDI/VDE-Gesellschaft Mess- und Automatisierungstechnik (GMA) 978-3-8007-3260-9 Fachtagung Sensoren und Messsysteme 15, 2010, Nürnberg ; Gesellschaft Mess- und Automatisierungstechnik 688 698 Fachbereich Medizintechnik und Technomathematik OPUS4-4380 Wissenschaftlicher Artikel Biselli, Manfred, biselli@fh-aachen.de; Bäcker, Matthias, baecker@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de; Schnitzler, Thomas, schnitzler@fh-aachen.de; Zang, Werner, zang@fh-aachen.de; Wagner, P., Entwicklung eines modularen festkörperbasierten Sensorsystems für die Überwachung von Zellkulturfermenationen Berlin VDE Verlag 2010 1 CD-ROM Sensoren und Messsysteme 2010 [Elektronische Ressource] : Vorträge der 15. ITG/GMA-Fachtagung vom 18. bis 19. Mai 2010 in Nürnberg / Informationstechnische Gesellschaft im VDE (ITG); VDI/VDE-Gesellschaft Mess- und Automatisierungstechnik (GMA) 978-3-8007-3260-9 Fachtagung Sensoren und Messsysteme 15, 2010, Nürnberg ; Gesellschaft Mess- und Automatisierungstechnik 688 691 Fachbereich Chemie und Biotechnologie OPUS4-4357 Wissenschaftlicher Artikel Bohrn, Ulrich, ; Stütz, Evamaria, ; Fleischer, Maximilian, ; Schöning, Michael Josef, schoening@fh-aachen.de; Wagner, Patrick, Eukaryotic cell lines as a sensitive layer for direct monitoring of carbon monoxide Weinheim Wiley 2011 5 Physica status solidi (a) : applications and material science. 208 (2011), H. 6 1862-6319 1345 1350 campus http://dx.doi.org/10.1002/pssa.201000924 Fachbereich Medizintechnik und Technomathematik OPUS4-4358 Wissenschaftlicher Artikel Bäcker, Matthias, baecker@fh-aachen.de; Pouyeshman, S., ; Schnitzler, Thomas, schnitzler@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de; Wagner, Patrick, ; Biselli, Manfred, biselli@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de A silicon-based multi-sensor chip for monitoring of fermentation processes Weinheim Wiley 2011 5 Physica status solidi (a) : applications and material science. 208 (2011), H. 6 1862-6319 1364 1369 campus http://dx.doi.org/10.1002/pssa.201001139 Fachbereich Medizintechnik und Technomathematik OPUS4-4365 Wissenschaftlicher Artikel Abouzar, Maryam H., ; Werner, Moritz, ; Schöning, Michael Josef, schoening@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de Capacitance-voltage and impedance-spectroscopy characteristics of nanoplate EISOI capacitors Berlin Wiley-VCH 2011 5 Physica status solidi (a) : applications and material science. 208 (2011), H. 6 1862-6319 1327 1332 campus http://dx.doi.org/10.1002/pssa.201001211 Fachbereich Medizintechnik und Technomathematik OPUS4-4366 Wissenschaftlicher Artikel Reisert, Steffen, reisert@fh-aachen.de; Geissler, Hanno, ; Flörke, Rudolf, ; Näther, Niko, naether@fh-aachen.de; Wagner, Patrick, ; Schöning, Michael Josef, schoening@fh-aachen.de Towards a multi-sensor system for the evaluation of aseptic processes employing hydrogen peroxide vapour (H2O2) Weinheim Wiley 2011 5 Physica status solidi (a) : applications and material science. 208 (2011), H. 6 1862-6319 1351 1356 campus http://dx.doi.org/10.1002/pssa.201001138 Fachbereich Medizintechnik und Technomathematik OPUS4-4367 Wissenschaftlicher Artikel Poghossian, Arshak, poghossian@fh-aachen.de; Wagner, Holger, ; Schöning, Michael Josef, schoening@fh-aachen.de Functional testing and characterisation of (bio-)chemical sensors on wafer level Amsterdam Elsevier 2011 4 Sensors and Actuators B: Chemical. 154 (2011), H. 2 1873-3077 EUROSENSORS XXIII 169 173 campus http://dx.doi.org/10.1016/j.snb.2009.11.024 Fachbereich Medizintechnik und Technomathematik OPUS4-4368 Wissenschaftlicher Artikel Wagner, Torsten, torsten.wagner@fh-aachen.de; Werner, Frederik, f.werner@fh-aachen.de; Miyamoto, Ko-Ichiro, ; Schöning, Michael Josef, schoening@fh-aachen.de; Yoshinobu, Tatsuo, A high-density multi-point LAPS set-up using a VCSEL array and FPGA control Amsterdam Elsevier 2011 4 Sensors and Actuators B: Chemical. 154 (2011), H. 2 1873-3077 EUROSENSORS XXIII 124 128 campus http://dx.doi.org/10.1016/j.snb.2010.03.009 Fachbereich Medizintechnik und Technomathematik OPUS4-4369 Wissenschaftlicher Artikel Miyamoto, Ko-ichiro, ; Wagner, Torsten, torsten.wagner@fh-aachen.de; Mimura, Shuhei, ; Kanoh, Shiníchiro, ; Yoshinobu, Tatsuo, ; Schöning, Michael Josef, schoening@fh-aachen.de Constant-phase-mode operation of the light-addressable potentiometric sensor Amsterdam Elsevier 2011 4 Sensors and Actuators B: Chemical. 154 (2011), H. 2 1873-3077 EUROSENSORS XXIII 119 123 campus http://dx.doi.org/10.1016/j.snb.2010.01.004 Fachbereich Medizintechnik und Technomathematik OPUS4-4391 Wissenschaftlicher Artikel Werner, Frederik, f.werner@fh-aachen.de; Groebel, Simone, groebel@fh-aachen.de; Wagner, Torsten, torsten.wagner@fh-aachen.de; Yoshinobu, Tatsuo, ; Selmer, Thorsten, selmer@fh-aachen.de; Baumann, Marcus, rektor@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de Überwachung der metabolischen Aktivität von Mikroorganismen zur Kontrolle des biologischen Prozesses im Biogasfermenter Düsseldorf VDI-Verl. 2011 292 S. : Ill., graph. Darst., Kt. Biogas 2011 : Energieträger der Zukunft ; 6. Fachtagung, Fachtagung Braunschweig, 08. und 09. Juni 2011 / VDI Energie und Umwelt 978-3-18-092121-1 Gesellschaft Energie und Umwelt ; Fachtagung Biogas ; (6 : ; 2011.06.08-09 : ; Braunschweig) ; VDI-Berichte ; 2121 285 286 Fachbereich Chemie und Biotechnologie OPUS4-4381 Wissenschaftlicher Artikel Kirchner, Patrick, kirchner@fh-aachen.de; Spelthahn, H., ; Schöning, Michael Josef, schoening@fh-aachen.de; Henkel, H., ; Schneider, A., ; Friedrich, P., ; Kolstad, J., ; Berger, J., Realisierung eines Polyimid-basierten kalorimetrischen Gassensors zur Inline-Überwachung der H2O2-Konzentration in aseptischen Abfüllanlagen Berlin VDE Verlag 2010 1 CD-ROM Sensoren und Messsysteme 2010 [Elektronische Ressource] : Vorträge der 15. ITG/GMA-Fachtagung vom 18. bis 19. Mai 2010 in Nürnberg / Informationstechnische Gesellschaft im VDE (ITG); VDI/VDE-Gesellschaft Mess- und Automatisierungstechnik (GMA) 978-3-8007-3260-9 Fachtagung Sensoren und Messsysteme 15, 2010, Nürnberg ; Gesellschaft Mess- und Automatisierungstechnik 607 612 Fachbereich Medizintechnik und Technomathematik OPUS4-4382 Wissenschaftlicher Artikel Werner, Frederik, f.werner@fh-aachen.de; Spelthahn, H., ; Schöning, Michael Josef, schoening@fh-aachen.de; Krumbe, C., ; Wagner, Torsten, torsten.wagner@fh-aachen.de; Yoshinobu, T., ; Keusgen, M., Neue Ansteuerungselektronik für LAPS-basierte Biosensoren zur gleichzeitig ortsaufgelösten Messung der pH-Konzentration Berlin VDE Verlag 2010 1 CD-ROM Sensoren und Messsysteme 2010 [Elektronische Ressource] : Vorträge der 15. ITG/GMA-Fachtagung vom 18. bis 19. Mai 2010 in Nürnberg / Informationstechnische Gesellschaft im VDE (ITG); VDI/VDE-Gesellschaft Mess- und Automatisierungstechnik (GMA) 978-3-8007-3260-9 Fachtagung Sensoren und Messsysteme 15, 2010, Nürnberg ; Gesellschaft Mess- und Automatisierungstechnik 109 114 Fachbereich Medizintechnik und Technomathematik OPUS4-4383 Wissenschaftlicher Artikel Poghossian, Arshak, poghossian@fh-aachen.de; Wagner, H., ; Schöning, Michael Josef, schoening@fh-aachen.de Automatisiertes „wafer level"-Testsystem zur Charakterisierung von siliziumbasierten Chemo- und Biosensoren Berlin VDE Verlag 2010 1 CD-ROM Sensoren und Messsysteme 2010 [Elektronische Ressource] : Vorträge der 15. ITG/GMA-Fachtagung vom 18. bis 19. Mai 2010 in Nürnberg / Informationstechnische Gesellschaft im VDE (ITG); VDI/VDE-Gesellschaft Mess- und Automatisierungstechnik (GMA) 978-3-8007-3260-9 Fachtagung Sensoren und Messsysteme 15, 2010, Nürnberg ; Gesellschaft Mess- und Automatisierungstechnik 89 92 Fachbereich Medizintechnik und Technomathematik OPUS4-4384 Wissenschaftlicher Artikel Wagner, Torsten, torsten.wagner@fh-aachen.de; Miyamoto, Ko-ichiro, ; Schöning, Michael Josef, schoening@fh-aachen.de; Yoshinobu, Tatsuo, Novel combination of digital light processing (DLP) and light-addressable potentiometric sensors (LAPS) for flexible chemical imaging 2010 3 Procedia Engineering. 5 (2010) 1877-7058 Eurosensor XXIV Conference 520 523 campus http://dx.doi.org/10.1016/j.proeng.2010.09.161 Fachbereich Medizintechnik und Technomathematik OPUS4-4385 Wissenschaftlicher Artikel Kirchner, Patrick, kirchner@fh-aachen.de; Oberländer, Jan, oberlaender@fh-aachen.de; Friedrich, Peter, ; Rysstad, G., ; Berger, J., ; Keusgen, M., ; Schöning, Michael Josef, schoening@fh-aachen.de Realization of a calorimetric gas sensor on polyimide foil for applications in aseptic food industry 2010 3 Procedia Engineering. 5 (2010) 1877-7058 Eurosensor XXIV Conference 264 267 campus http://dx.doi.org/10.1016/j.proeng.2010.09.098 Fachbereich Medizintechnik und Technomathematik OPUS4-4386 Wissenschaftlicher Artikel Miyamoto, Ko-ichiro, ; Kaneko, Kazumi, ; Matsuo, Akira, ; Wagner, Torsten, torsten.wagner@fh-aachen.de; Kanoh, Shin`ichiro, ; Schöning, Michael Josef, schoening@fh-aachen.de; Yoshinobu, Tatsuo, Miniaturized chemical imaging sensor system using an OLED display panel 2010 3 Procedia Engineering. 5 (2010) 1877-7058 Eurosensor XXIV Conference 516 519 campus http://dx.doi.org/10.1016/j.proeng.2010.09.160 Fachbereich Medizintechnik und Technomathematik OPUS4-4387 Wissenschaftlicher Artikel Bohrn, U., ; Stütz, E., ; Fleischer, M., ; Schöning, Michael Josef, schoening@fh-aachen.de Real-time detection of CO by eukaryotic cells 2010 3 Procedia Engineering. 5 (2010) 1877-7058 Eurosensor XXIV Conference 17 20 campus http://dx.doi.org/10.1016/j.proeng.2010.09.037 Fachbereich Medizintechnik und Technomathematik OPUS4-4388 Wissenschaftlicher Artikel Reisert, Steffen, reisert@fh-aachen.de; Geissler, H., ; Florke, R., ; Wagner, P., ; Wagner, Torsten, torsten.wagner@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de Controlling aseptic sterilization processes by means of a multi-sensor system New York IEEE 2011 4 2011 IEEE Workshop on Merging Fields of Computational Intelligence and Sensor Technology ; 11.-15. April 2011 Paris, France 18 22 campus http://dx.doi.org/10.1109/MFCIST.2011.5949519 Fachbereich Medizintechnik und Technomathematik OPUS4-4389 Wissenschaftlicher Artikel Heiden, W., ; Turek, M., ; Schöning, Michael Josef, schoening@fh-aachen.de TasteIT : Analyzing chemical sensor data using fuzzy logic New York IEEE 2011 5 978-1-4244-9910-6 2011 IEEE Workshop on Merging Fields of Computational Intelligence and Sensor Technology ; 11.-15. April 2011 Paris, France 1 6 campus http://dx.doi.org/10.1109/MFCIST.2011.5949520 Fachbereich Medizintechnik und Technomathematik OPUS4-4390 Wissenschaftlicher Artikel Heiden, W., ; Turek, M., ; Schöning, Michael Josef, schoening@fh-aachen.de Analysis of chemical sensor data Ufa State Aviation Technical Univ. 2011 VIII, 163 S. : graf. Darst. Proceedings of the 4th Russian-German Workshop "Innovation Information Technologies: Theory and practice" : Ufa, Russia, April 8-13, 2011 / eds. Yupsova, Nafisa ... 978-5-4221-0159-7 76 81 Fachbereich Medizintechnik und Technomathematik OPUS4-4355 Wissenschaftlicher Artikel Paczkowski, Sebastian, ; Weißbecker, Bernhard, ; Schöning, Michael Josef, schoening@fh-aachen.de; Schütz, Stefan, Biosensors on the Basis of Insect Olfaction Dordrecht [u.a.] Springer 2011 XII, 267 S. : Ill., graph. Darst Insect biotechnology / Andreas Vilcinskas, ed. 978-90-481-9640-1 Biologically-inspired system ; 2 225 240 Fachbereich Medizintechnik und Technomathematik OPUS4-4436 Wissenschaftlicher Artikel Malzahn, Kerstin, ; Windmiller, Joshua Ray, ; Valdés-Ramírez, Gabriela, ; Wang, Joseph, ; Schöning, Michael Josef, schoening@fh-aachen.de Wearable electrochemical sensors for in situ analysis in marine environments Cambridge Royal Society of Chemistry 2011 5 Analyst. 136 (2011), H. 14 0003-2654 2912 2917 campus http://dx.doi.org/10.1039/C1AN15193B Fachbereich Medizintechnik und Technomathematik OPUS4-4437 Wissenschaftlicher Artikel Gasparyan, Ferdinand V., ; Poghossian, Arshak, poghossian@fh-aachen.de; Vitusevich, Svetlana A., ; Petrychuk, Mykhaylo V., ; Sydoruk, Viktor A., ; Siqueira, José R. Jr., ; Oliveira, Osvaldo N. Jr., ; Offenhäusser, Andreas, ; Schöning, Michael Josef, schoening@fh-aachen.de Low-Frequency Noise in Field-Effect Devices Functionalized With Dendrimer/Carbon-Nanotube Multilayers New York IEEE 2011 7 IEEE Sensors Journal. 11 (2011), H. 1 1530-437X 142 149 campus http://dx.doi.org/10.1109/JSEN.2010.2052355 Fachbereich Medizintechnik und Technomathematik OPUS4-4440 Wissenschaftlicher Artikel Bäcker, Matthias, baecker@fh-aachen.de; Delle, L., ; Poghossian, Arshak, poghossian@fh-aachen.de; Biselli, Manfred, biselli@fh-aachen.de; Zang, Werner, zang@fh-aachen.de; Wagner, P., ; Schöning, Michael Josef, schoening@fh-aachen.de Electrochemical sensor array for bioprocess monitoring Amsterdam Elsevier 2011 5 Electrochimica Acta (2011) 56 26 9673 9678 campus http://dx.doi.org/10.1016/j.electacta.2011.04.030 Fachbereich Chemie und Biotechnologie OPUS4-4484 Wissenschaftlicher Artikel Wagner, Torsten, torsten.wagner@fh-aachen.de; Miyamoto, K., ; Werner, Frederik, f.werner@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de; Yoshinobu, T., Flexible electrochemical imaging with "zoom-in" functionality by using a new type of light-addressable potentiometric sensor New York IEEE 2011 2 2011 16th International Solid-State Sensors, Actuators and Microsystems Conference (TRANSDUCERS) , Date: 5-9 June 2011 2133 2135 campus http://dx.doi.org/10.1109/TRANSDUCERS.2011.5969294 Fachbereich Medizintechnik und Technomathematik OPUS4-4485 Wissenschaftlicher Artikel Miyamoto, K., ; Wagner, Torsten, torsten.wagner@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de; Yoshinobu, T., Multi-well structure for cell culture on the chemical imaging sensor New York IEEE 2011 2 2011 16th International Solid-State Sensors, Actuators and Microsystems Conference (TRANSDUCERS) , Date: 5-9 June 2011 2130 2132 campus http://dx.doi.org/10.1109/TRANSDUCERS.2011.5969264 Fachbereich Medizintechnik und Technomathematik OPUS4-4613 Wissenschaftlicher Artikel Huck, Christina, huck@fh-aachen.de; Jolly, Christina, ; Wagner, Patrick, ; Poghossian, Arshak, poghossian@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de One-chip integrated dual amperometric/field-effect sensor for the detection of dissolved hydrogen Amsterdam Elsevier 2011 3 Procedia Engineering. 25 (2011) 1877-7058 EurosensorsXXV ; Proc. Eurosensors XXV, September 4-7, 2011, Athens, Greece 1161 1164 campus http://dx.doi.org/10.1016/j.proeng.2011.12.286 Fachbereich Medizintechnik und Technomathematik OPUS4-4614 Wissenschaftlicher Artikel Wagner, Torsten, torsten.wagner@fh-aachen.de; Miyamoto, Ko-ichiro, ; Shigihara, Noriko, ; Schöning, Michael Josef, schoening@fh-aachen.de; Yoshinobu, Tatsuo, Microfluidic systems with free definable sensor spots by an integrated light-addressable potentiometric sensor Amsterdam Elsevier 2011 3 Procedia Engineering. 25 (2011) 1877-7058 EurosensorsXXV ; Proc. Eurosensors XXV, September 4-7, 2011, Athens, Greece 791 794 campus http://dx.doi.org/10.1016/j.proeng.2011.12.194 Fachbereich Medizintechnik und Technomathematik OPUS4-4615 Wissenschaftlicher Artikel Bohrn, U., ; Stütz, E., ; Fuchs, K., ; Fleischer, M., ; Schöning, Michael Josef, schoening@fh-aachen.de; Wagner, P., Air Quality Monitoring using a Whole-Cell based Sensor System Amsterdam Elsevier 2011 3 Procedia Engineering. 25 (2011) 1877-7058 EurosensorsXXV ; Proc. Eurosensors XXV, September 4-7, 2011, Athens, Greece 1421 1424 campus http://dx.doi.org/10.1016/j.proeng.2011.12.351 Fachbereich Medizintechnik und Technomathematik OPUS4-4616 Wissenschaftlicher Artikel Werner, Frederik, f.werner@fh-aachen.de; Wagner, Torsten, torsten.wagner@fh-aachen.de; Miyamoto, Ko-ichiro, ; Yoshinobu, Tatsuo, ; Schöning, Michael Josef, schoening@fh-aachen.de High speed and high resolution chemical imaging based on a new type of OLED-LAPS set-up Amsterdam Elsevier 2011 3 Procedia Engineering. 25 (2011) 1877-7058 EurosensorsXXV ; Proc. Eurosensors XXV, September 4-7, 2011, Athens, Greece 346 349 campus http://dx.doi.org/10.1016/j.proeng.2011.12.085 Fachbereich Medizintechnik und Technomathematik OPUS4-4535 Wissenschaftlicher Artikel Poghossian, Arshak, poghossian@fh-aachen.de; Malzahn, K., ; Abouzar, Maryam H., ; Mehndiratta, P., ; Katz, E., ; Schöning, Michael Josef, schoening@fh-aachen.de Integration of biomolecular logic gates with field-effect transducers Amsterdam Elsevier 2011 4 Electrochimica Acta. 56 (2011), H. 26 0013-4686 9661 9665 campus http://dx.doi.org/10.1016/j.electacta.2011.01.102 Fachbereich Medizintechnik und Technomathematik OPUS4-4689 Wissenschaftlicher Artikel Bäcker, Matthias, baecker@fh-aachen.de; Raue, Markus, raue@fh-aachen.de; Schusser, Sebastian, schusser@fh-aachen.de; Jeitner, C., ; Breuer, L., ; Wagner, P., ; Poghossian, Arshak, poghossian@fh-aachen.de; Förster, Arnold, foerster@fh-aachen.de; Mang, Thomas, mang@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de Microfluidic chip with integrated microvalves based on temperature- and pH-responsive hydrogel thin films - 2012 6 Physica Status Solidi / A. 209 (2012), H. 5 1862-6319 839 845 campus http://dx.doi.org/10.1002/pssa.201100763 Fachbereich Chemie und Biotechnologie OPUS4-4674 Wissenschaftlicher Artikel Poghossian, Arshak, poghossian@fh-aachen.de; Abouzar, Maryam H., ; Schöning, Michael Josef, schoening@fh-aachen.de (Bio-­)chemical sensor array based on nanoplate SOI capacitors - 2012 0 Nanoscale Science and Technology (NS&T´12) : Proceedings Book Humboldt Kolleg <2012, Tunisia> ; Tunisia, 17-19 March, 2012 / ed. by Michael J. Schöning ; Adnane Abdelghani Proceedings of the 2nd Humboldt Kolleg, Hammamet, Tunisia, 17-19 March, 2012 Organizer: Alexander von Humboldt Stiftung, Germany. pdf 184 p. 31 31 weltweit http://opus.bibliothek.fh-aachen.de/opus/volltexte/2012/354/ Fachbereich Medizintechnik und Technomathematik OPUS4-4675 Wissenschaftlicher Artikel Bohrn, U., ; Stütz, E., ; Fleischer, M., ; Schöning, Michael Josef, schoening@fh-aachen.de; Wagner, P., Towards a paradigm change - mammalian cells as sensitive biosensor layers for the detection of unexpected toxic substances in air - 2012 0 Nanoscale Science and Technology (NS&T´12) : Proceedings Book Humboldt Kolleg <2012, Tunisia> ; Tunisia, 17-19 March, 2012 / ed. by Michael J. Schöning ; Adnane Abdelghani Proceedings of the 2nd Humboldt Kolleg, Hammamet, Tunisia, 17-19 March, 2012 Organizer: Alexander von Humboldt Stiftung, Germany. pdf 184 p. 44 44 weltweit http://opus.bibliothek.fh-aachen.de/opus/volltexte/2012/354/ Fachbereich Medizintechnik und Technomathematik OPUS4-4676 Wissenschaftlicher Artikel Reisert, Steffen, reisert@fh-aachen.de; Geissler, H., ; Flörke, R., ; Weiler, C., ; Wagner, P., ; Schöning, Michael Josef, schoening@fh-aachen.de Characterisation of aseptic sterilisation processes using an electronic nose - 2012 0 Nanoscale Science and Technology (NS&T´12) : Proceedings Book Humboldt Kolleg <2012, Tunisia> ; Tunisia, 17-19 March, 2012 / ed. by Michael J. Schöning ; Adnane Abdelghani Proceedings of the 2nd Humboldt Kolleg, Hammamet, Tunisia, 17-19 March, 2012 Organizer: Alexander von Humboldt Stiftung, Germany. pdf 184 p. 45 45 weltweit http://opus.bibliothek.fh-aachen.de/opus/volltexte/2012/354/ Fachbereich Medizintechnik und Technomathematik OPUS4-4677 Wissenschaftlicher Artikel Schusser, Sebastian, schusser@fh-aachen.de; Leinhos, Marcel, leinhos@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de; Wagner, Patrick, ; Schöning, Michael Josef, schoening@fh-aachen.de Biopolymer-degradation monitoring by chip-­based impedance spectroscopy technique - 2012 0 Nanoscale Science and Technology (NS&T´12) : Proceedings Book Humboldt Kolleg <2012, Tunisia> ; Tunisia, 17-19 March, 2012 / ed. by Michael J. Schöning ; Adnane Abdelghani Proceedings of the 2nd Humboldt Kolleg, Hammamet, Tunisia, 17-19 March, 2012 Organizer: Alexander von Humboldt Stiftung, Germany. pdf 184 p. 47 47 weltweit http://opus.bibliothek.fh-aachen.de/opus/volltexte/2012/354/ Fachbereich Medizintechnik und Technomathematik OPUS4-4679 Wissenschaftlicher Artikel Bäcker, Matthias, baecker@fh-aachen.de; Rakowski, D., ; Poghossian, Arshak, poghossian@fh-aachen.de; Biselli, Manfred, biselli@fh-aachen.de; Wagner, Patrick, ; Schöning, Michael Josef, schoening@fh-aachen.de Chip-based amperometric enzyme sensor system for monitoring of bioprocesses by flow-injection analysis Amsterdam Elsevier 2013 5 Journal of Biotechnology. Vol. 163 (2012), iss. 4 Vol. 163 Iss. 4 371 376 campus http://dx.doi.org/10.1016/j.jbiotec.2012.03.014 Fachbereich Chemie und Biotechnologie OPUS4-4680 Wissenschaftlicher Artikel Abouzar, Maryam H., ; Poghossian, Arshak, poghossian@fh-aachen.de; Cherstvy, Andrey G., ; Pedraza, Angela M., ; Ingebrandt, Sven, ; Schöning, Michael Josef, schoening@fh-aachen.de Label-free electrical detection of DNA by means of field-effect nanoplate capacitors: Experiments and modeling - 2012 9 Physica Status Solidi / A. 209 (2012), H. 5 1862-6319 925 934 campus http://dx.doi.org/10.1002/pssa.201100710 Fachbereich Medizintechnik und Technomathematik OPUS4-4682 Wissenschaftlicher Artikel Yoshinobu, Tatsuo, ; Miyamoto, Ko-Ichiro, ; Wagner, Torsten, torsten.wagner@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de Miniaturized and high-speed chemical imaging systems - 2012 9 Nano-Boomedical Engineering 2012 :Proceedings of the Tohoku University Global Centre of Excellence Programme / Sakura Hall, Tohoku University, Sendai Japan, 5 – 6 March 2012 / ed. by Takami Yamaguchi 386 395 bezahl http://dx.doi.org/10.1142/9781848169067_0045 Fachbereich Medizintechnik und Technomathematik OPUS4-4666 Wissenschaftlicher Artikel Grinsven, Bart van, ; Bon, Natalie vanden, ; Strauven, Hannelore, ; Grieten, Lars, ; Murib, Mohammed, ; Jiménez Monroy, Kathia L., ; Janssens, Stoffel D., ; Haenen, Ken, ; Schöning, Michael Josef, schoening@fh-aachen.de; Vermeeren, Veronique, ; Ameloot, Marcel, ; Michiels, Luc, ; Thoelen, Ronald, ; Ceuninck, Ward de, ; Wagner, Patrick, Heat-Transfer Resistance at Solid-Liquid Interfaces: A Tool for The Detection of Single Nucleotide Polymorphisms in DNA. 2012 9 ACS Nano. 6 (2012), H. 3 1936-086X 2712 2721 campus http://dx.doi.org/10.1021/nn300147e Fachbereich Medizintechnik und Technomathematik OPUS4-4667 Wissenschaftlicher Artikel Arida, Hassan A., ; Al-haddad, Ameera, ; Schöning, Michael Josef, schoening@fh-aachen.de New Solid-State Organic Membrane Based Lead-Selective Micro-Electrode 2011 9 International Journal of Electrochemical Science. 6 (2011), H. 9 1452-3981 3858 3867 weltweit http://www.electrochemsci.org/papers/vol6/6093858.pdf Fachbereich Medizintechnik und Technomathematik OPUS4-4752 Wissenschaftlicher Artikel Werner, Frederik, f.werner@fh-aachen.de; Groebel, Simone, groebel@fh-aachen.de; Krumbe, Christoph, ; Wagner, Torsten, torsten.wagner@fh-aachen.de; Selmer, Thorsten, selmer@fh-aachen.de; Yoshinobu, Tatsuo, ; Baumann, Marcus, rektor@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de Nutrient concentration-sensitive microorganism-based biosensor - 2012 4 Physica Status Solidi / A 209 1862-6319 5 900 904 campus http://dx.doi.org/10.1002/pssa.201100801 Fachbereich Chemie und Biotechnologie OPUS4-4762 Wissenschaftlicher Artikel Spelthahn, Heiko, spelthahn@fh-aachen.de; Kirsanov, Dmitry, ; Legin, Andrey, ; Osterrath, Thomas, ; Schubert, Jürgen, ; Zander, Willi, ; Schöning, Michael Josef, schoening@fh-aachen.de Development of a thin-film sensor array for analytical monitoring of heavy metals in aqueous solutions - 2012 6 Physica Status Solidi / A. 209 (2012), H. 5 1862-6319 885 891 campus http://dx.doi.org/10.1002/pssa.201100733 Fachbereich Medizintechnik und Technomathematik OPUS4-4857 Wissenschaftlicher Artikel Bohrn, Ulrich, ; Stütz, Evamaria, ; Fleischer, Maximilian, ; Schöning, Michael Josef, schoening@fh-aachen.de; Wagner, Patrick, Using a cell-based gas biosensor for investigation of adverse effects of acetone vapors in vitro Amsterdam Elsevier 2013 7 Biosensors and Bioelectronics. 40 (2013), H. 1 0956-5663 393 400 campus http://dx.doi.org/10.1016/j.bios.2012.08.029 Fachbereich Medizintechnik und Technomathematik OPUS4-4929 Wissenschaftlicher Artikel Murib, Mohammed S., ; Tran, Anh Quang, ; Ceuninck, Ward de, ; Schöning, Michael Josef, schoening@fh-aachen.de; Nesladek, Milos, ; Serpengüzel, Ali, ; Wagner, Patrick, Analysis of an optical biosensor based on elastic light scattering from diamond-, glass-, and sapphire microspheres Deoxyribonucleic acid (DNA) and protein recognition are now standard tools in biology. In addition, the special optical properties of microsphere resonators expressed by the high quality factor (Q-factor) of whispering gallery modes (WGMs) or morphology dependent resonances (MDRs) have attracted the attention of the biophotonic community. Microsphere-based biosensors are considered as powerful candidates to achieve label-free recognition of single molecules due to the high sensitivity of their WGMs. When the microsphere surface is modified with biomolecules, the effective refractive index and the effective size of the microsphere change resulting in a resonant wavelength shift. The transverse electric (TE) and the transverse magnetic (TM) elastic light scattering intensity of electromagnetic waves at 600 and 1400 nm are numerically calculated for DNA and unspecific binding of proteins to the microsphere surface. The effect of changing the optical properties was studied for diamond (refractive index 2.34), glass (refractive index 1.50), and sapphire (refractive index 1.75) microspheres with a 50 µm radius. The mode spacing, the linewidth of WGMs, and the shift of resonant wavelength due to the change in radius and refractive index, were analyzed by numerical simulations. Preliminary results of unspecific binding of biomolecules are presented. The calculated shift in WGMs can be used for biomolecules detection. Weinheim Wiley-VCH 2012 6 Physica Status Solidi A 209 Special Issue: "Fundamentals and Applications of Diamond" 9 1804 1810 10.1002/pssa.201100795 campus https:/doi.org/10.1002/pssa.201100795 Fachbereich Medizintechnik und Technomathematik OPUS4-4940 Wissenschaftlicher Artikel Huck, Christina, huck@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de; Wagner, Patrick, ; Schöning, Michael Josef, schoening@fh-aachen.de Combined amperometric/field-effect sensor for the detection of dissolved hydrogen Real-time and reliable monitoring of the biogas process is crucial for a stable and efficient operation of biogas production in order to avoid digester breakdowns. The concentration of dissolved hydrogen (H₂) represents one of the key parameters for biogas process control. In this work, a one-chip integrated combined amperometric/field-effect sensor for monitoring the dissolved H₂ concentration has been developed for biogas applications. The combination of two different transducer principles might allow a more accurate and reliable measurement of dissolved H₂ as an early warning indicator of digester failures. The feasibility of the approach has been demonstrated by simultaneous amperometric/field-effect measurements of dissolved H₂ concentrations in electrolyte solutions. Both, the amperometric and the field-effect transducer show a linear response behaviour in the H₂ concentration range from 0.1 to 3% (v/v) with a slope of 198.4 ± 13.7 nA/% (v/v) and 14.9 ± 0.5 mV/% (v/v), respectively. Amsterdam Elsevier 2012 5 Sensors and actuators B: Chemical 187 Part of special issue "Selected Papers from the 14th International Meeting on Chemical Sensors" 168 173 10.1016/j.snb.2012.10.050 campus https://doi.org/10.1016/j.snb.2012.10.050 Fachbereich Medizintechnik und Technomathematik OPUS4-4946 Wissenschaftlicher Artikel Iken, Heiko, ; Kirsanov, D., ; Legin, A., ; Schöning, Michael Josef, schoening@fh-aachen.de Novel Thin-Film Polymeric Materials for the Detection of Heavy Metals A variety of transition metals, e.g., copper, zinc, cadmium, lead, etc. are widely used in industry as components for wires, coatings, alloys, batteries, paints and so on. The inevitable presence of transition metals in industrial processes implies the ambition of developing a proper analytical technique for their adequate monitoring. Most of these elements, especially lead and cadmium, are acutely toxic for biological organisms. Quantitative determination of these metals at low activity levels in different environmental and industrial samples is therefore a vital task. A promising approach to achieve an at-side or on-line monitoring on a miniaturized and cost efficient way is the combination of a common potentiometric sensor array with heavy metal-sensitive thin-film materials, like chalcogenide glasses and polymeric materials, respectively. Amsterdam Elsevier 2012 3 Procedia Engineering Part of special issue "26th European Conference on Solid-State Transducers, EUROSENSOR 2012" 47 322 325 10.1016/j.proeng.2012.09.148 campus https://doi.org/10.1016/j.proeng.2012.09.148 Fachbereich Medizintechnik und Technomathematik OPUS4-4947 Wissenschaftlicher Artikel Miyamoto, K., ; Ichimura, H., ; Wagner, Torsten, torsten.wagner@fh-aachen.de; Yoshinobu, T., ; Schöning, Michael Josef, schoening@fh-aachen.de Chemical Imaging of ion Diffusion in a Microfluidic Channel The chemical imaging sensor is a chemical sensor which is capable of visualizing the spatial distribution of chemical species in sample solution. In this study, a novel measurement system based on the chemical imaging sensor was developed to observe the inside of a Y-shaped microfluidic channel while injecting two sample solutions from two branches. From the collected chemical images, it was clearly observed that the injected solutions formed laminar flows in the microfluidic channel. In addition, ion diffusion across the laminar flows was observed. This label-free method can acquire quantitative data of ion distribution and diffusion in microfluidic devices, which can be used to determine the diffusion coefficients, and therefore, the molecular weights of chemical species in the sample solution. Amsterdam Elsevier 2012 3 Procedia Engineering Part of special issue "26th European Conference on Solid-State Transducers, EUROSENSOR 2012" 47 886 889 10.1016/j.proeng.2012.09.289 campus https://doi.org/10.1016/j.proeng.2012.09.289 Fachbereich Medizintechnik und Technomathematik OPUS4-4948 Wissenschaftlicher Artikel Wagner, Torsten, torsten.wagner@fh-aachen.de; Shigiahara, N., ; Miyamoto, K., ; Suzurikawa, J., ; Finger, F., ; Schöning, Michael Josef, schoening@fh-aachen.de; Yoshinobu, T., Light-addressable Potentiometric Sensors and Light-addressable Electrodes as a Combined Sensor-and-manipulator Microsystem with High Flexibility This work describes the novel combination of the light-addressable electrode (LAE) and the light-addressable potentiometric sensor (LAPS) into a microsystem set-up. Both the LAE as well as the LAPS shares the principle of addressing the active spot by means of a light beam. This enables both systems to manipulate resp. to detect an analyte with a high spatial resolution. Hence, combining both principles into a single set-up enables the active stimulation e.g., by means of electrolysis and a simultaneous observation e.g., the response of an entrapped biological cell by detection of extracellular pH changes. The work will describe the principles of both technologies and the necessary steps to integrate them into a single set-up. Furthermore, examples of application and operation of such systems will be presented. Amsterdam Elsevier 2012 3 Procedia Engineering Part of special issue "26th European Conference on Solid-State Transducers, EUROSENSOR 2012" 47 890 893 10.1016/j.proeng.2012.09.290 campus https://doi.org/10.1016/j.proeng.2012.09.290 Fachbereich Medizintechnik und Technomathematik OPUS4-4949 Wissenschaftlicher Artikel Poghossian, Arshak, poghossian@fh-aachen.de; Weil, M. H., ; Bäcker, Matthias, baecker@fh-aachen.de; Mayer, D., ; Schöning, Michael Josef, schoening@fh-aachen.de Field-effect Devices Functionalised with Gold-Nanoparticle/Macromolecule Hybrids: New Opportunities for a Label-Free Biosensing Field-effect capacitive electrolyte-insulator-semiconductor (EIS) sensors functionalised with citrate-capped gold nanoparticles (AuNP) have been used for the electrostatic detection of macromolecules by their intrinsic molecular charge. The EIS sensor detects the charge changes in the AuNP/macromolecule hybrids induced by the adsorption or binding events. A feasibility of the proposed detection scheme has been exemplary demonstrated by realising EIS sensors for the detection of poly-D-lysine molecules. Amsterdam Elsevier 2012 3 Procedia Engineering Part of special issue "26th European Conference on Solid-State Transducers, EUROSENSOR 2012" 47 273 276 10.1016/j.proeng.2012.09.136 campus https://doi.org/10.1016/j.proeng.2012.09.136 Fachbereich Medizintechnik und Technomathematik OPUS4-4960 Wissenschaftlicher Artikel Werner, Frederik, f.werner@fh-aachen.de; Takenaga, Shoko, ; Taki, Hidenori, ; Sawada, Kazuaki, ; Schöning, Michael Josef, schoening@fh-aachen.de Comparison of label-free ACh-imaging sensors based on CCD and LAPS Amsterdam Elsevier 2013 7 Sensors and Actuators B: Chemical (2012) 177 0925-4005 745 752 campus http://dx.doi.org/10.1016/j.snb.2012.11.012 Fachbereich Medizintechnik und Technomathematik OPUS4-4966 Wissenschaftlicher Artikel Kirchner, Patrick, kirchner@fh-aachen.de; Oberländer, Jan, oberlaender@fh-aachen.de; Suco, Henri-Pierre, ; Rysstad, Gunnar, ; Schöning, Michael Josef, schoening@fh-aachen.de Monitoring the microbicidal effectiveness of gaseous hydrogen peroxide in sterilisation processes by means of a calorimetric gas sensor In the present work, a novel method for monitoring sterilisation processes with gaseous H2O2 in combination with heat activation by means of a specially designed calorimetric gas sensor was evaluated. Therefore, the sterilisation process was extensively studied by using test specimens inoculated with Bacillus atrophaeus spores in order to identify the most influencing process factors on its microbicidal effectiveness. Besides the contact time of the test specimens with gaseous H2O2 varied between 0.2 and 0.5 s, the present H2O2 concentration in a range from 0 to 8% v/v (volume percent) had a strong influence on the microbicidal effectiveness, whereas the change of the vaporiser temperature, gas flow and humidity were almost negligible. Furthermore, a calorimetric H2O2 gas sensor was characterised in the sterilisation process with gaseous H2O2 in a wide range of parameter settings, wherein the measurement signal has shown a linear response against the H2O2 concentration with a sensitivity of 4.75 °C/(% v/v). In a final step, a correlation model by matching the measurement signal of the gas sensor with the microbial inactivation kinetics was established that demonstrates its suitability as an efficient method for validating the microbicidal effectiveness of sterilisation processes with gaseous H2O2. Amsterdam Elsevier 2013 8 Food control 31 2 530 538 campus http://dx.doi.org/10.1016/j.foodcont.2012.11.048 Fachbereich Medizintechnik und Technomathematik OPUS4-5042 Konferenzveröffentlichung Schusser, Sebastian, schusser@fh-aachen.de; Vaeßen, Christiane, vaessen@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de 5. Graduiertentagung der FH Aachen 15. November 2012 Tagungsband der 5. Graduiertentagung der FH Aachen am 15. November 2012 2012 52 urn:nbn:de:hbz:a96-opus-50425 FH Aachen OPUS4-5149 Wissenschaftlicher Artikel Hennemann, Jörg, ; Kohl, Claus-Dieter, ; Reisert, Steffen, reisert@fh-aachen.de; Kirchner, Patrick, kirchner@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de Copper oxide nanofibres for detection of hydrogen peroxide vapour at high concentrations We present a sensor concept based on copper(II)oxide (CuO) nanofibres for the detection of hydrogen peroxide (H2O2) vapour in the percent per volume (% v/v) range. The fibres were produced by using the electrospinning technique. To avoid water condensation in the pores, the fibres were initially modified by an exposure to H2S to get an enclosed surface. By a thermal treatment at 350 °C the fibres were oxidised back to CuO. Thereby, the visible pores disappear which was verified by SEM analysis. The fibres show a decrease of resistance with increasing H2O2 concentration which is due to the fact that hydrogen peroxide is an oxidising gas and CuO a p-type semiconductor. The sensor shows a change of resistance within the minute range to the exposure until the maximum concentration of 6.9% v/v H2O2. At operating temperatures below 450 °C the corresponding sensor response to a concentration of 4.1% v/v increases. The sensor shows a good reproducibility of the signal at different measurements. CuO seems to be a suitable candidate for the detection of H2O2 vapour at high concentrations. Resistance behaviour of the sensor under exposure to H2O2 vapours between 2.3 and 6.9% v/v at an operating temperature of 450 °C. Weinheim Wiley 2013 4 physica status solidi (a) Vol. 210 Iss. 5 859 863 campus http://dx.doi.org/10.1002/pssa.201200775 Fachbereich Medizintechnik und Technomathematik OPUS4-5316 Wissenschaftlicher Artikel Poghossian, Arshak, poghossian@fh-aachen.de; Weil, M., ; Cherstvy, A. G., ; Schöning, Michael Josef, schoening@fh-aachen.de Electrical monitoring of polyelectrolyte multilayer formation by means of capacitive field-effect devices Berlin Springer 2013 11 Analytical and bioanalytical chemistry Vol. 405 Iss. 20 6425 6436 campus http://link.springer.com/content/pdf/10.1007%2Fs00216-013-6951-9.pdf Fachbereich Medizintechnik und Technomathematik OPUS4-5317 Wissenschaftlicher Artikel Schusser, Sebastian, schusser@fh-aachen.de; Leinhos, Marcel, leinhos@fh-aachen.de; Bäcker, Matthias, baecker@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de; Wagner, Patrick, ; Schöning, Michael Josef, schoening@fh-aachen.de Impedance spectroscopy: A tool for real-time in situ monitoring of the degradation of biopolymers Weinheim Wiley 2013 5 Physica Status Solidi (A). Vol. 210 (2013), iss. 5 905 910 campus http://onlinelibrary.wiley.com/doi/10.1002/pssa.201200941/pdf Fachbereich Medizintechnik und Technomathematik OPUS4-5320 Wissenschaftlicher Artikel Huck, Christina, huck@fh-aachen.de; Schiffels, Johannes, schiffels@fh-aachen.de; Herrera, Cony N., ; Schelden, Maximilian, ; Selmer, Thorsten, selmer@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de; Baumann, Marcus, rektor@fh-aachen.de; Wagner, Patrick, ; Schöning, Michael Josef, schoening@fh-aachen.de Metabolic responses of Escherichia coli upon glucose pulses captured by a capacitive field-effect sensor Weinheim Wiley-VCH 2013 5 Physica Status Solidi (A). Vol. 210 (2013), iss. 5 926 931 campus http://onlinelibrary.wiley.com/doi/10.1002/pssa.201200900/pdf Fachbereich Chemie und Biotechnologie OPUS4-5244 Wissenschaftlicher Artikel Itabashi, Akinori, ; Kosaka, Naoki, ; Miyamoto, Ko-ichiro, ; Wagner, Torsten, torsten.wagner@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de High-speed chemical imaging system based on front-side-illuminated LAPS Amsterdam Elsevier 2013 6 Sensors and actuators B: Chemical. 182 (2013) 315 321 campus http://dx.doi.org/10.1016/j.snb.2013.03.016 Fachbereich Medizintechnik und Technomathematik OPUS4-5321 Wissenschaftlicher Artikel Murib, M. S., ; Grinsven, B. van, ; Grieten, L., ; Janssens, S. D., ; Vermeeren, V., ; Eersels, K., ; Broeders, J., ; Ameloot, M., ; Michiels, L., ; Ceuninck, W. De, ; Haenen, K., ; Schöning, Michael Josef, schoening@fh-aachen.de; Wagner, Patrick, Electronic monitoring of chemical DNA denaturation on nanocrystalline diamond electrodes with different molarities and flow rates Berlin Wiley-VCH 2013 6 Physica Status Solidi (A). Vol. 210 (2013), iss. 5 911 917 campus http://onlinelibrary.wiley.com/doi/10.1002/pssa.201200934/pdf Fachbereich Medizintechnik und Technomathematik OPUS4-5573 Wissenschaftlicher Artikel Miyamoto, Ko-ichiro, ; Ichimura, Hiroki, ; Wagner, Torsten, torsten.wagner@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de; Yoshinobu, Tatsuo, Chemical imaging of the concentration profile of ion diffusion in a microfluidic channel Amsterdam Elsevier 2013 5 Sensors and actuators. B: Chemical. In Press Vol. 189 240 245 campus http://www.sciencedirect.com/science/article/pii/S0925400513004905 Fachbereich Medizintechnik und Technomathematik OPUS4-5575 Wissenschaftlicher Artikel Bohrn, Ulrich, ; Mucha, Andreas, ; Werner, Frederik, f.werner@fh-aachen.de; Trattner, Barbara, ; Bäcker, Matthias, baecker@fh-aachen.de; Krumbe, Christoph, ; Schienle, Meinrad, ; Stütz, Evamaria, ; Schmitt-Landsiedel, Doris, ; Fleischer, Maximilian, ; Wagner, Patrick, ; Schöning, Michael Josef, schoening@fh-aachen.de A critical comparison of cell-based sensor systems for the detection of Cr (VI) in aquatic environment Amsterdam Elsevier 2013 7 Sensors and actuators. B: Chemical Vol. 182 58 65 campus http://www.sciencedirect.com/science/article/pii/S0925400513002402 Fachbereich Medizintechnik und Technomathematik OPUS4-5613 Wissenschaftlicher Artikel Kramer, Friederike, ; Halamkova, Lenka, ; Poghossian, Arshak, poghossian@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de; Katz, Evgeny, ; Halamek, Jan, Biocatalytic analysis of biomarkers for forensic identification of ethnicity between Caucasian and African American Cambridge Royal Society of Chemistry 2013 6 The analyst. August 2013 Vol. 138 6251 6257 bezahl http://dx.doi.org/10.1039/C3AN01062G Fachbereich Medizintechnik und Technomathematik OPUS4-5680 Wissenschaftlicher Artikel Schusser, Sebastian, schusser@fh-aachen.de; Menzel, S., ; Bäcker, Matthias, baecker@fh-aachen.de; Leinhos, Marcel, leinhos@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de; Wagner, P., ; Schöning, Michael Josef, schoening@fh-aachen.de Degradation of thin poly(lactic acid) films: characterization by capacitance-voltage, atomic force microscopy, scanning electron microscopy and contact-angle measurements Amsterdam Elsevier 2013 5 Electrochimica Acta Vol. 113 779 784 campus http://dx.doi.org/10.1016/j.electacta.2013.08.025 Fachbereich Medizintechnik und Technomathematik OPUS4-5905 Wissenschaftlicher Artikel Iken, Heiko, iken@fh-aachen.de; Ahlborn, K., ; Gerlach, F., ; Vonau, W., ; Zander, W., ; Schubert, J., ; Schöning, Michael Josef, schoening@fh-aachen.de Development of redox glasses and subsequent processing by means of pulsed laser deposition for realizing silicon-based thin-film sensors Amsterdam Elsevier 2013 Electrochimica acta Available online 30.8.2013 campus http://dx.doi.org/10.1016/j.electacta.2013.08.092 Fachbereich Medizintechnik und Technomathematik OPUS4-5989 Wissenschaftlicher Artikel Bandodkar, Amay J., ; Molinnus, Denise, molinnus@fh-aachen.de; Mirza, Omar, ; Guinovart, Tomas, ; Windmiller, Joshua R., ; Valdes-Ramirez, Gabriela, ; Andrade, Francisco J., ; Schöning, Michael Josef, schoening@fh-aachen.de; Wang, Joseph, Epidermal tattoo potentiometric sodium sensors with wireless signal transduction for continuous non-invasive sweat monitoring This article describes the fabrication, characterization and application of an epidermal temporary-transfer tattoo-based potentiometric sensor, coupled with a miniaturized wearable wireless transceiver, for real-time monitoring of sodium in the human perspiration. Sodium excreted during perspiration is an excellent marker for electrolyte imbalance and provides valuable information regarding an individual's physical and mental wellbeing. The realization of the new skin-worn non-invasive tattoo-like sensing device has been realized by amalgamating several state-of-the-art thick film, laser printing, solid-state potentiometry, fluidics and wireless technologies. The resulting tattoo-based potentiometric sodium sensor displays a rapid near-Nernstian response with negligible carryover effects, and good resiliency against various mechanical deformations experienced by the human epidermis. On-body testing of the tattoo sensor coupled to a wireless transceiver during exercise activity demonstrated its ability to continuously monitor sweat sodium dynamics. The real-time sweat sodium concentration was transmitted wirelessly via a body-worn transceiver from the sodium tattoo sensor to a notebook while the subjects perspired on a stationary cycle. The favorable analytical performance along with the wearable nature of the wireless transceiver makes the new epidermal potentiometric sensing system attractive for continuous monitoring the sodium dynamics in human perspiration during diverse activities relevant to the healthcare, fitness, military, healthcare and skin-care domains. Amsterdam Elsevier 2014 6 Biosensors and bioelectronics 54 603 609 10.1016/j.bios.2013.11.039 bezahl https://doi.org/10.1016/j.bios.2013.11.039 Fachbereich Medizintechnik und Technomathematik OPUS4-5995 Wissenschaftlicher Artikel Reisert, Steffen, reisert@fh-aachen.de; Geissler, Hanno, ; Flörke, Rudolf, ; Weiler, Christian, ; Wagner, Patrick, ; Schöning, Michael Josef, schoening@fh-aachen.de Characterisation of aseptic sterilisation processes using an electronic nose Genève Inderscience Enterprises 2013 14 International journal of nanotechnology Vol. 10 No. 5-7 470 484 bezahl http://dx.doi.org/10.1504/IJNT.2013.053517 Fachbereich Medizintechnik und Technomathematik OPUS4-6003 Wissenschaftlicher Artikel Miyamoto, Ko-ichiro, ; Hirayama, Yuji, ; Wagner, Torsten, torsten.wagner@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de; Yoshinobu, Tatsuo, Visualization of enzymatic reaction in a microfluidic channel using chemical imaging sensor Amsterdam Elsevier 2013 Electrochimica acta Publ. online campus http://dx.doi.org/10.1016/j.electacta.2013.08.089 Fachbereich Medizintechnik und Technomathematik OPUS4-6088 misc Ingebrandt, Sven, ; Wagner, Patrick, ; Schöning, Michael Josef, schoening@fh-aachen.de Engineering of functional interfaces / guest eds. Sven Ingebrandt ; Patrick Wagner ; Michael J. Schöning 2013 Physica Status Solidi (A) Vol. 210 Iss. 5 845 campus http://dx.doi.org/10.1002/pssa.201322718 Fachbereich Medizintechnik und Technomathematik OPUS4-6111 Konferenzveröffentlichung Takenaga, Shoko, takenaga@fh-aachen.de; Herrera, Cony F., ; Werner, Frederik, f.werner@fh-aachen.de; Biselli, Manfred, biselli@fh-aachen.de; Schnitzler, Thomas, schnitzler@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de; Öhlschläger, Peter, oehlschlaeger@fh-aachen.de; Wagner, Torsten, torsten.wagner@fh-aachen.de Detection of the metabolic activity of cells by differential measurements based on a single light-addressable potentiometric sensor chip 2013 4 11. Dresdner Sensor-Symposium : 9.-11.12.2013 978-3-9813484-5-3 63 67 weltweit http://dx.doi.org/10.5162/11dss2013/3.4 Fachbereich Chemie und Biotechnologie OPUS4-6112 Konferenzveröffentlichung Schusser, Sebastian, schusser@fh-aachen.de; Bäcker, Matthias, baecker@fh-aachen.de; Leinhos, Marcel, leinhos@fh-aachen.de; Krischer, M., ; Wenzel, L., ; Poghossian, Arshak, poghossian@fh-aachen.de; Wagner, Patrick, ; Schöning, Michael Josef, schoening@fh-aachen.de Sensorkonzept zur in vitro Echtzeitmessung des Degradationsverhaltens von biodegradierbaren Biopolymeren 2013 3 11. Dresdner Sensor-Symposium : 9.-11.12.2013 978-3-9813484-5-3 174 177 weltweit http://dx.doi.org/10.5162/11dss2013/A11 Fachbereich Medizintechnik und Technomathematik OPUS4-6113 Konferenzveröffentlichung Wu, Chunsheng, c.wu@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de; Werner, Frederik, f.werner@fh-aachen.de; Bronder, Thomas, bronder@fh-aachen.de; Bäcker, Matthias, baecker@fh-aachen.de; Wang, Ping, ; Schöning, Michael Josef, schoening@fh-aachen.de An application of a scanning light-addressable potentiometric sensor for label-free DNA detection 2013 4 11. Dresdner Sensor-Symposium : 9.-11.12.2013 978-3-9813484-5-3 164 168 weltweit http://dx.doi.org/10.5162/11dss2013/A9 Fachbereich Medizintechnik und Technomathematik OPUS4-6114 Konferenzveröffentlichung Oberländer, Jan, oberlaender@fh-aachen.de; Reisert, Steffen, reisert@fh-aachen.de; Kirchner, Patrick, kirchner@fh-aachen.de; Wagner, Patrick, ; Schöning, Michael Josef, schoening@fh-aachen.de Kalorimetrische Gassensoren zur H2O2-Detektion in aseptischen Sterilisationsprozessen 2013 4 11. Dresdner Sensor-Symposium : 9.-11.12.2013 978-3-9813484-5-3 234 238 weltweit http://dx.doi.org/10.5162/11dss2013/B7 Fachbereich Medizintechnik und Technomathematik OPUS4-6115 Konferenzveröffentlichung Huck, Christina, huck@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de; Bäcker, Matthias, baecker@fh-aachen.de; Zander, W., ; Schubert, J., ; Sukoyan, L. H., ; Begoyan, V., ; Buniatyan, V. V., ; Wagner, Patrick, ; Schöning, Michael Josef, schoening@fh-aachen.de Chemische Sensoren mit Bariumstrontiumtitanat als funktionelle Schicht zur Multiparameterdetektion 2013 4 11. Dresdner Sensor-Symposium : 9.-11.12.2013 978-3-9813484-5-3 368 372 weltweit http://dx.doi.org/10.5162/11dss2013/F15 Fachbereich Medizintechnik und Technomathematik OPUS4-6116 Wissenschaftlicher Artikel Buniatyan, V., ; Huck, Christina, huck@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de; Aroutiounian, V. M., ; Schöning, Michael Josef, schoening@fh-aachen.de BaxSr1-x TiO3/pc-Si heterojunction capacitance Yerevan National Academy of Sciences of Armenia 2013 9 Armenian journal of physics 6 4 188 197 weltweit https://www.semanticscholar.org/paper/BaxSr1-x-TiO3-pc-Si-HETEROJUNCTION-CAPACITANCE-Buniatyan-Huck/c5f43e74443683f2527475bfca122b1d19daf396 Fachbereich Medizintechnik und Technomathematik OPUS4-6117 Wissenschaftlicher Artikel Buniatyan, V., ; Huck, Christina, huck@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de; Aroutiounian, V. M., ; Schöning, Michael Josef, schoening@fh-aachen.de BaxSr1-x TiO3/pc-Si heterojunction Yerevan National Academy of Sciences of Armenia 2013 10 Armenian journal of physics 6 4 177 187 weltweit https://www.semanticscholar.org/paper/BaxSr1-x-TiO3-pc-Si-HETEROJUNCTION-Buniatyan-Huck/8d0f6be4f0c66b8ab26177ea61f8574a99446958 Fachbereich Medizintechnik und Technomathematik OPUS4-6108 misc Abdelghani, Adnane, ; Menaa, Bouzid, ; Obare, Sherine O., ; Schöning, Michael Josef, schoening@fh-aachen.de Special issue on nanoscale science and technology / guest eds.: Adnane Abdelghani, Bouzid Menaa, Sherine O. Obare, Michael J. Schöning 2013 246 International journal of nanotechnology Vol. 10 No. 5-7 373 619 Fachbereich Medizintechnik und Technomathematik OPUS4-6110 Wissenschaftlicher Artikel Bäcker, Matthias, baecker@fh-aachen.de; Schusser, Sebastian, schusser@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de Degradationsverhalten bioabbaubarer Polymere : siliziumbasierte Sensorik zur Überwachung Weinheim Wiley-VCH 2013 1 GIT Labor-Fachzeitschrift 32 33 weltweit http://www.git-labor.de/forschung/materialien/degradationsverhalten-bioabbaubarer-polymere Fachbereich Medizintechnik und Technomathematik OPUS4-6255 Wissenschaftlicher Artikel Miyamoto, Ko-ichiro, ; Itabashi, Akinori, ; Wagner, Torsten, torsten.wagner@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de; Yoshinobu, Tatsuo, High-speed chemical imaging inside a microfluidic channel In this study, a high-speed chemical imaging system was developed for visualization of the interior of a microfluidic channel. A microfluidic channel was constructed on the sensor surface of the light-addressable potentiometric sensor (LAPS), on which the ion concentrations could be measured in parallel at up to 64 points illuminated by optical fibers. The temporal change of pH distribution inside the microfluidic channel was recorded at a maximum rate of 100 frames per second (fps). The high frame rate allowed visualization of moving interfaces and plugs in the channel even at a flow velocity of 111 mm/s, which suggests the feasibility of plug-based microfluidic devices for flow-injection analysis (FIA). Amsterdam Elsevier 2014 6 Sensors and actuators. B: Chemical 194 521 527 10.1016/j.snb.2013.12.090 bezahl https://doi.org/10.1016/j.snb.2013.12.090 Fachbereich Medizintechnik und Technomathematik OPUS4-6338 Konferenzveröffentlichung Kreyer, Jörg, kreyer@fh-aachen.de; Stollenwerk, Dominik, stollenwerk@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de Tagung des Forschernachwuchses der FH Aachen 20. November 2013 / ed.: J. Kreyer, D. Stollenwerk, M. J. Schöning Aachen FH Aachen 2013 64 S. Fachbereich Medizintechnik und Technomathematik OPUS4-6339 Wissenschaftlicher Artikel Moseley, Fiona, ; Halamek, Jan, ; Kramer, Friederike, ; Poghossian, Arshak, poghossian@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de; Katz, Evgeny, An enzyme-based reversible CNOT logic gate realized in a flow system An enzyme system organized in a flow device was used to mimic a reversible Controlled NOT (CNOT) gate with two input and two output signals. Reversible conversion of NAD⁺ and NADH cofactors was used to perform a XOR logic operation, while biocatalytic hydrolysis of p-nitrophenyl phosphate resulted in an Identity operation working in parallel. The first biomolecular realization of a CNOT gate is promising for integration into complex biomolecular networks and future biosensor/biomedical applications. Cambridge Royal Society of Chemistry 2014 3 Analyst 139 8 1839 1842 10.1039/C4AN00133H campus https://doi.org/10.1039/C4AN00133H Fachbereich Medizintechnik und Technomathematik OPUS4-6390 Wissenschaftlicher Artikel Leinhos, Marcel, leinhos@fh-aachen.de; Schusser, Sebastian, schusser@fh-aachen.de; Bäcker, Matthias, baecker@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de Micromachined multi-parameter sensor chip for the control of polymer-degradation medium It is well known that the degradation environment can strongly influence the biodegradability and kinetics of biodegradation processes of polymers. Therefore, besides the monitoring of the degradation process, it is also necessary to control the medium in which the degradation takes place. In this work, a micromachined multi-parameter sensor chip for the control of the polymer-degradation medium has been developed. The chip combines a capacitive field-effect pH sensor, a four-electrode electrolyte-conductivity sensor and a thin-film Pt-temperature sensor. The results of characterization of individual sensors are presented. In addition, the multi-parameter sensor chip together with an impedimetric polymer-degradation sensor was simultaneously characterized in degradation solutions with different pH and electrolyte conductivity. The obtained results demonstrate the feasibility of the multi-parameter sensor chip for the control of the polymer-degradation medium. Weinheim Wiley-VCH 2014 5 Physica Status Solidi (A) : special issue on engineering and functional interfaces 211 6 1346 1351 10.1002/pssa.201330364 campus https://doi.org/10.1002/pssa.201330364 Fachbereich Medizintechnik und Technomathematik OPUS4-6409 Wissenschaftlicher Artikel Huck, Christina, huck@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de; Kerroumi, Iman, ; Schusser, Sebastian, schusser@fh-aachen.de; Bäcker, Matthias, baecker@fh-aachen.de; Zander, Willi, ; Schubert, Jürgen, ; Buniatyan, Vahe V., ; Martirosyan, Norayr W., ; Wagner, Patrick, ; Schöning, Michael Josef, schoening@fh-aachen.de Multiparameter sensor chip with Barium Strontium Titanate as multipurpose material It is well known that biochemical and biotechnological processes are strongly dependent and affected by a variety of physico-chemical parameters such as pH value, temperature, pressure and electrolyte conductivity. Therefore, these quantities have to be monitored or controlled in order to guarantee a stable process operation, optimization and high yield. In this work, a sensor chip for the multiparameter detection of three physico-chemical parameters such as electrolyte conductivity, pH and temperature is realized using barium strontium titanate (BST) as multipurpose material. The chip integrates a capacitively coupled four-electrode electrolyte-conductivity sensor, a capacitive field-effect pH sensor and a thin-film Pt-temperature sensor. Due to the multifunctional properties of BST, it is utilized as final outermost coating layer of the processed sensor chip and serves as passivation and protection layer as well as pH-sensitive transducer material at the same time. The results of testing of the individual sensors of the developed multiparameter sensor chip are presented. In addition, a quasi-simultaneous multiparameter characterization of the sensor chip in buffer solutions with different pH value and electrolyte conductivity is performed. To study the sensor behavior and the suitability of BST as multifunctional material under harsh environmental conditions, the sensor chip was exemplarily tested in a biogas digestate. Weinheim Wiley-VCH 2014 7 Electroanalysis 26 5 980 987 10.1002/elan.201400076 campus https://doi.org/10.1002/elan.201400076 Fachbereich Medizintechnik und Technomathematik OPUS4-6410 Wissenschaftlicher Artikel Bäcker, Matthias, baecker@fh-aachen.de; Kramer, F., ; Huck, Christina, huck@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de; Bratov, A., ; Abramova, N., ; Schöning, Michael Josef, schoening@fh-aachen.de Planar and 3D interdigitated electrodes for biosensing applications: The impact of a dielectric barrier on the sensor properties Planar and three-dimensional (3D) interdigitated electrodes (IDE) with electrode digits separated by an insulating barrier of different heights were electrochemically characterized and compared in terms of their sensing properties. Due to the impact of the surface resistance, both types of IDE structures display a non-linear behavior in low-ionic strength solutions. The experimental data were fitted to an electrical equivalent circuit and interpreted taking into account the surface-charge-governed properties. The effect of a charged polyelectrolyte layer electrostatically assembled onto the sensor surface on the surface resistance in solutions with different KCl concentration is studied. In case of the same electrode footprint, 3D-IDEs show a larger cell constant and a higher sensitivity to molecular adsorption than that of planar IDEs. The obtained results demonstrate the potential of 3D-IDEs as a new transducer structure for a direct label-free sensing of charged molecules. Weinheim Wiley-VCH 2014 6 Physica Status Solidi (A) - Applications and Materials Science 211 6 1357 1363 10.1002/pssa.201330416 campus https://doi.org/10.1002/pssa.201330416 Fachbereich Medizintechnik und Technomathematik OPUS4-6391 Teil eines Buches Schöning, Michael Josef, schoening@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de; Glück, Olaf, ; Thust, Marion, Electrochemical composition measurement 2nd ed. Boca Raton, Fa. CRC Pr. 2014 NaN Measurement, instrumentation, and sensors handbook: electromagnetic, optical, radiation, chemical, and biomedical measuremen 978-1-4398-4891-3 55-1 55-54 campus https://doi.org/10.1201/b15664 Fachbereich Medizintechnik und Technomathematik OPUS4-6394 Wissenschaftlicher Artikel Huck, Christina, huck@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de; Bäcker, Matthias, baecker@fh-aachen.de; Chaudhuri, S., ; Zander, W., ; Schubert, J., ; Begoyan, V. K., ; Buniatyan, V. V., ; Wagner, P., ; Schöning, Michael Josef, schoening@fh-aachen.de Capacitively coupled electrolyte-conductivity sensor based on high-k material of barium strontium titanate Amsterdam Elsevier 2014 7 Sensors and actuators. B: Chemical 198 102 109 10.1016/j.snb.2014.02.103 bezahl https//doi.org/10.1016/j.snb.2014.02.103 Fachbereich Medizintechnik und Technomathematik OPUS4-6395 Wissenschaftlicher Artikel Oberländer, Jan, oberlaender@fh-aachen.de; Kirchner, Patrick, kirchner@fh-aachen.de; Boyen, Hans-Gerd, ; Schöning, Michael Josef, schoening@fh-aachen.de Detection of hydrogen peroxide vapor by use of manganese(IV) oxide as catalyst for calorimetric gas sensors In this work, the catalyst manganese(IV) oxide (MnO2), of calorimetric gas sensors (to monitor the sterilization agent vaporized hydrogen peroxide) has been investigated in more detail. Chemical analyses by means of X-ray-induced photoelectron spectroscopy have been performed to unravel the surface chemistry prior and after exposure to hydrogen peroxide vapor at elevated temperature, as applied in the sterilization processes of beverage cartons. The surface characterization reveals a change in oxidation states of the metal oxide catalyst after exposure to hydrogen peroxide. Additionally, a cleaning effect of the catalyst, which itself is attached to the sensor surface by means of a polymer interlayer, could be observed. Weinheim Wiley-VCH 2014 4 Physica status solidi A: Applications and materials science 211 6 1372 1376 10.1002/pssa.201330359 campus http://dx.doi.org/10.1002/pssa.201330359 Fachbereich Medizintechnik und Technomathematik OPUS4-6355 misc Ahlborn, Kristina, ; Gerlach, Frank, ; Iken, Heiko, iken@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de; Vonau, Winfried, Miniaturisierte, potentiometrische Indikatorelektrode und Verfahren zu deren Herstellung : Offenlegungsschrift 2012 7 S. weltweit https://depatisnet.dpma.de/DepatisNet/depatisnet?action=pdf&docid=DE102012014861A1 Fachbereich Medizintechnik und Technomathematik OPUS4-6487 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Biselli, Manfred, biselli@fh-aachen.de; Selmer, Thorsten, selmer@fh-aachen.de; Öhlschläger, Peter, oehlschlaeger@fh-aachen.de; Baumann, Marcus, rektor@fh-aachen.de; Förster, Arnold, foerster@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de Forschung „zwischen" den Disziplinen: das Institut für Nano- und Biotechnologien "Biologie trifft Mikroelektronik", das Motto des Instituts für Nano- und Biotechnologien (INB) an der FH Aachen, unterstreicht die zunehmende Bedeutung interdisziplinär geprägter Forschungsaktivitäten. Der thematische Zusammenschluss grundständiger Disziplinen, wie die Physik, Elektrotechnik, Chemie, Biologie sowie die Materialwissenschaften, lässt neue Forschungsgebiete entstehen, ein herausragendes Beispiel hierfür ist die Nanotechnologie: Hier werden neue Werkstoffe und Materialien entwickelt, einzelne Nanopartikel oder Moleküle und deren Wechselwirkung untersucht oder Schichtstrukturen im Nanometerbereich aufgebaut, die neue und vorher nicht bekannte Eigenschaften hervorbringen. Vor diesem Hintergrund bündelt das im Jahre 2006 gegründete INB die an der FH Aachen vorhandenen Kompetenzen von derzeit insgesamt sieben Laboratorien auf den Gebieten der Halbleitertechnik und Nanoelektronik, Nanostrukturen und DNA-Sensorik, der Chemo- und Biosensorik, der Enzymtechnologie, der Mikrobiologie und Pflanzenbiotechnologie, der Zellkulturtechnik, sowie der Roten Biotechnologie synergetisch. In der Nano- und Biotechnologie steckt außergewöhnliches Potenzial! Nicht zuletzt deshalb stellen sich die Forscher der Herausforderung, in diesem Bereich gemeinsam zu forschen und Schnittstellen zu nutzen, um so bei der Gestaltung neuartiger Ideen und Produkte mitzuwirken, die zukünftig unser alltägliches Leben verändern werden. Im Folgenden werden die verschiedenen Forschungsbereiche kurz zusammenfassend vorgestellt und vorhandene Interaktionen anhand von exemplarisch ausgewählten, aktuellen Forschungsprojekten skizziert. Ober-Ramstadt Dr. Beyer Internet-Beratung 2012 11 Seiten Analytik news : das Online-Labormagazin für Labor und Analytik Publ. online weltweit https://analytik.news/fachartikel/2012/41.html Fachbereich Chemie und Biotechnologie OPUS4-6488 Bericht Schöning, Michael Josef, schoening@fh-aachen.de; Selmer, Thorsten, selmer@fh-aachen.de; Baumann, Marcus, rektor@fh-aachen.de Schlussbericht zum Projekt "Bio-LAPS" : Optimierung des Betriebs eines Biogasfermenters mit Hilfe eines Feldeffekt-Biosensors auf Basis eines lichtadressierbaren potentiometrischen Sensors (LAPS) : Laufzeit: 01.09.2008 bis 31.01.2012 : Förderkennzeichen 07NR264 bzw.22026407 Berlin BMELV 2012 44 S. weltweit http://edok01.tib.uni-hannover.de/edoks/e01fb13/734124988.pdf Fachbereich Medizintechnik und Technomathematik OPUS4-6441 Wissenschaftlicher Artikel Takenaga, Shoko, takenaga@fh-aachen.de; Biselli, Manfred, biselli@fh-aachen.de; Schnitzler, Thomas, schnitzler@fh-aachen.de; Öhlschläger, Peter, oehlschlaeger@fh-aachen.de; Wagner, Torsten, torsten.wagner@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de Toward multi-analyte bioarray sensors: LAPS-based on-chip determination of a Michaelis-Menten-like kinetics for cell culturing The metabolic activity of Chinese hamster ovary (CHO) cells was observed using a light-addressable potentiometric sensor (LAPS). The dependency toward different glucose concentrations (17-200 mM) follows a Michaelis-Menten kinetics trajectory with Kₘ = 32.8 mM, and the obtained Kₘ value in this experiment was compared with that found in literature. In addition, the pH shift induced by glucose metabolism of tumor cells transfected with the HPV-16 genome (C3 cells) was successfully observed. These results indicate the possibility to determine the tumor cells metabolism with a LAPS-based measurement device. Weinheim Wiley-VCH 2014 5 Physica status solidi A : Applications and materials science 211 6 1410 1415 10.1002/pssa.201330464 campus https://doi.org/10.1002/pssa.201330464 Fachbereich Chemie und Biotechnologie OPUS4-6444 Wissenschaftlicher Artikel Wu, Chunsheng, c.wu@fh-aachen.de; Bronder, Thomas, bronder@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de; Werner, Frederik, f.werner@fh-aachen.de; Bäcker, Matthias, baecker@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de Label-free electrical detection of DNA with a multi-spot LAPS: First step towards light-addressable DNA chips A multi-spot (4 × 4 spots) light-addressable potentiometric sensor (MLAPS) consisting of an Al-p-Si-SiO2 structure has been applied for the label-free electrical detection of DNA (deoxyribonucleic acid) immobilization and hybridization by the intrinsic molecular charge for the first time. Single-stranded probe ssDNA molecules (20 bases) were covalently immobilized onto the silanized SiO2 gate surface. The unspecific adsorption of mismatch ssDNA on the MLAPS gate surface was blocked by bovine serum albumin molecules. To reduce the screening effect and to achieve a high sensor signal, the measurements were performed in a low ionic-strength solution. The photocurrent-voltage (I-V) curves were simultaneously recorded on all 16 spots after each surface functionalization step. Large shifts of I-V curves of 25 mV were registered after the DNA immobilization and hybridization event. In contrast, a small potential shift (∼5 mV) was observed in case of mismatch ssDNA, revealing good specificity of the sensor. The obtained results demonstrate the potential of the MLAPS as promising transducer platform for the multi-spot label-free electrical detection of DNA molecules by their intrinsic molecular charge. Weinheim Wiley-VCH 2014 5 Physica status solidi A : Applications and materials science 211 6 1423 1428 10.1002/pssa.201330442 campus https://doi.org/10.1002/pssa.201330442 Fachbereich Medizintechnik und Technomathematik OPUS4-6445 Wissenschaftlicher Artikel Poghossian, Arshak, poghossian@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de Label-free sensing of biomolecules with field-effect devices for clinical applications Among the variety of transducer concepts proposed for label-free detection of biomolecules, the semiconductor field-effect device (FED) is one of the most attractive platforms. As medical techniques continue to progress towards diagnostic and therapies based on biomarkers, the ability of FEDs for a label-free, fast and real-time detection of multiple pathogenic and physiologically relevant molecules with high specificity and sensitivity offers very promising prospects for their application in point-of-care and personalized medicine for an early diagnosis and treatment of diseases. The presented paper reviews recent advances and current trends in research and development of different FEDs for label-free, direct electrical detection of charged biomolecules by their intrinsic molecular charge. The authors are mainly focusing on the detection of the DNA hybridization event, antibody-antigen affinity reaction as well as clinically relevant biomolecules such as cardiac and cancer biomarkers. Weinheim Wiley-VCH 2014 16 Electroanalysis 26 6 1197 1213 10.1002/elan.201400073 campus http://dx.doi.org/10.1002/elan.201400073 Fachbereich Medizintechnik und Technomathematik OPUS4-6497 Wissenschaftlicher Artikel Guo, Yuanyuan, ; Seki, Kosuke, ; Miyamoto, Ko-ichiro, ; Wagner, Torsten, torsten.wagner@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de; Yoshinobu, Tatsuo, Novel photoexcitation method for light-addressable potentiometric sensor with higher spatial resolution A novel photoexcitation method for the light-addressable potentiometric sensor (LAPS) is proposed to achieve a higher spatial resolution of chemical images. The proposed method employs a combined light source that consists of a modulated light probe, which generates the alternating photocurrent signal, and a ring of constant illumination surrounding it. The constant illumination generates a sheath of carriers with increased concentration which suppresses the spread of photocarriers by enhanced recombination. A device simulation was carried out to verify the effect of constant illumination on the spatial resolution, which demonstrated that a higher spatial resolution can be obtained. Bristol IOP 2014 Applied physics express : APEX 7 6 067301-4 10.7567/APEX.7.067301 bezahl https://doi.org/10.7567/APEX.7.067301 Fachbereich Medizintechnik und Technomathematik OPUS4-6500 Teil eines Buches Poghossian, Arshak, poghossian@fh-aachen.de; Weiland, Maryam, ; Schöning, Michael Josef, schoening@fh-aachen.de Nanoplate field-effect capacitors: a new transducer structure for multiparameter (bio-) chemical sensing In this chapter, we describe developments on the use of impedance spectroscopy and ultrathin films of different materials in the analysis of liquid samples via weak, non-bonding molecular interactions. Despite the lack of intrinsic selectivity in many cases, the simplicity of the sensor is quite attractive and enhanced by the nanostructured thin nature of the materials forming the sensing units. Moreover, it is possible to incorporate materials capable of molecular recognition, such as enzymes, extending the e-tongue concept to biosensing. Advantage can also be taken from the supramolecular interactions between the ultrathin films and the liquid samples under analysis, and integration of sensing units in microarrays for high-performance, high-throughput sensors. Singapore Jenny Stanford Publishing 2014 40 Multisensor system for chemical analysis : materials and sensors. Ed. by Larissa Lvova ... 978-981-4411-15-8 ; 978-981-4411-16-5 333 373 campus http://dx.doi.org/10.1201/b15491-10 Fachbereich Medizintechnik und Technomathematik OPUS4-6502 Wissenschaftlicher Artikel Wagner, Patrick, ; Doll, Theodor, ; Schöning, Michael Josef, schoening@fh-aachen.de Engineering of functional interfaces / Patrick Wagner ; Theodor Doll ; Michael J. Schöning (eds.) Weinheim Wiley-VCH 2014 0 Physica status solidi (A) : Applications and materials science 211 6 1339 1339 10.1002/pssa.201470241 campus https://doi.org/10.1002/pssa.201470241 Fachbereich Medizintechnik und Technomathematik OPUS4-6417 Wissenschaftlicher Artikel Guo, Yuanyuan, ; Miyamoto, Ko-ichiro, ; Wagner, Torsten, torsten.wagner@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de; Yoshinobu, Tatsuo, Theoretical study and simulation of light-addressable potentiometric sensors The light-addressable potentiometric sensor (LAPS) is a semiconductor-based potentiometric sensor using a light probe with an ability of detecting the concentration of biochemical species in a spatially resolved manner. As an important biomedical sensor, research has been conducted to improve its performance, for instance, to realize high-speed measurement. In this work, the idea of facilitating the device-level simulation, instead of using an equivalent-circuit model, is presented for detailed analysis and optimization of the performance of the LAPS. Both carrier distribution and photocurrent response have been simulated to provide new insight into both amplitude-mode and phase-mode operations of the LAPS. Various device parameters can be examined to effectively design and optimize the LAPS structures and setups for enhanced performance. Weinheim Wiley-VCH 2014 5 Physica status solidi (A) : applications and materials 211 6 1467 1472 10.1002/pssa.201330354 campus https://doi.org/10.1002/pssa.201330354 Fachbereich Chemie und Biotechnologie OPUS4-6543 Wissenschaftlicher Artikel Riedel, Marc, ; Kartchemnik, Julia, ; Schöning, Michael Josef, schoening@fh-aachen.de; Lisdat, Fred, Impedimetric DNA detection - steps forward to sensorial application This study describes a label-free impedimetric sensor based on short ssDNA recognition elements for the detection of hybridization events. We concentrate on the elucidation of the influence of target length and recognition sequence position on the sensorial performance. The impedimetric measurements are performed in the presence of the redox system ferri-/ferrocyanide and show an increase in charge transfer resistance upon hybridization of ssDNA to the sensor surface. Investigations on the impedimetric signal stability demonstrate a clear influence of the buffers used during the sensor preparation and the choice of the passivating mercaptoalcanol compound. A stable sensor system has been developed, enabling a reproducible detection of 25mer target DNA in the low nanomolar range. After hybridization, a sensor regeneration can be reached with deionized water by adjustment of effective convection conditions, ensuring a sensor reusability. By investigations of longer targets with overhangs exposed to the solution, we can demonstrate applicability of the impedimetric detection for longer ssDNA. However, a decreasing charge transfer resistance change (ΔRct) is found by extending the overhang. As a strategy to increase the impedance change for longer target strands, the position of the recognition sequence can be designed in a way that a small overhang is exposed to the electrode surface. This is found to result in an increase in the relative Rct change. These results suggest that DNA and consequently negative charge near the electrode possess a larger impact on the impedimetric signal than DNA further away. Columbus ACS Publications 2014 7 Analytical chemistry 86 (2014) 15 7867 7874 10.1021/ac501800q campus https://doi.org/10.1021/ac501800q Fachbereich Medizintechnik und Technomathematik OPUS4-6621 Wissenschaftlicher Artikel Guo, Yuanyuan, ; Miyamoto, Ko-ichiro, ; Wagner, Torsten, torsten.wagner@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de; Yoshinobu, Tatsuo, Device simulation of the light-addressable potentiometric sensor for the investigation of the spatial resolution As a semiconductor-based electrochemical sensor, the light-addressable potentiometric sensor (LAPS) can realize two dimensional visualization of (bio-)chemical reactions at the sensor surface addressed by localized illumination. Thanks to this imaging capability, various applications in biochemical and biomedical fields are expected, for which the spatial resolution is critically significant. In this study, therefore, the spatial resolution of the LAPS was investigated in detail based on the device simulation. By calculating the spatiotemporal change of the distributions of electrons and holes inside the semiconductor layer in response to a modulated illumination, the photocurrent response as well as the spatial resolution was obtained as a function of various parameters such as the thickness of the Si substrate, the doping concentration, the wavelength and the intensity of illumination. The simulation results verified that both thinning the semiconductor substrate and increasing the doping concentration could improve the spatial resolution, which were in good agreement with known experimental results and theoretical analysis. More importantly, new findings of interests were also obtained. As for the dependence on the wavelength of illumination, it was found that the known dependence was not always the case. When the Si substrate was thick, a longer wavelength resulted in a higher spatial resolution which was known by experiments. When the Si substrate was thin, however, a longer wavelength of light resulted in a lower spatial resolution. This finding was explained as an effect of raised concentration of carriers, which reduced the thickness of the space charge region. The device simulation was found to be helpful to understand the relationship between the spatial resolution and device parameters, to understand the physics behind it, and to optimize the device structure and measurement conditions for realizing higher performance of chemical imaging systems. Amsterdam Elsevier 2014 6 Sensors and actuators B: Chemical 204 659 665 10.1016/j.snb.2014.08.016 bezahl https://doi.org/10.1016/j.snb.2014.08.016 Fachbereich Medizintechnik und Technomathematik OPUS4-6622 Wissenschaftlicher Artikel Reisert, Steffen, reisert@fh-aachen.de; Geissler, H., ; Weiler, C., ; Wagner, P., ; Schöning, Michael Josef, schoening@fh-aachen.de Multiple sensor-type system for monitoring the microbicidal effectiveness of aseptic sterilisation processes 2015 7 Food control Vol. 47 615 622 campus http://dx.doi.org/10.1016/j.foodcont.2014.07.063 Fachbereich Medizintechnik und Technomathematik OPUS4-6624 Wissenschaftlicher Artikel Khaydukova, M. M., ; Zadorozhnaya, O. A., ; Kirsanov, D. O., ; Iken, Heiko, iken@fh-aachen.de; Rolka, David, d.rolka@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de; Babain, V. A., ; Vlasov, Yu. G., ; Legin, A. V., Multivariate processing of atomic-force microscopy images for detection of the response of plasticized polymeric membranes The possibility of using the atomic-force microscopy as a method for detection of the analytical signal from plasticized polymeric sensor membranes was analyzed. The surfaces of cadmium-selective membranes based on two polymeric matrices were examined. The digital images were processed with multivariate image analysis techniques. A correlation was found between the surface profile of an ion-selective membrane and the concentration of the ion in solution. Dordrecht Springer 2014 7 Russian journal of applied chemistry 87 3 307 314 10.1134/S1070427214030112 bezahl https://doi.org/10.1134/S1070427214030112 Fachbereich Medizintechnik und Technomathematik OPUS4-6629 Konferenzveröffentlichung Buniatyan, V. V., ; Huck, Christina, huck@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de; Rustamyan, L. G., ; Hovnikyan, H. H., Equivalent circuit and optimization of impedance characteristics of an electrolyte conductivity sensor 2014 7 Proceedings of State Engineering University Armenia : Series Information technologies, electronics, radio engineering Iss. 17 No. 1 69 76 weltweit http://banber.seua.am/bamber/ITER%2017-1%20Final240614.pdf#page=69 Fachbereich Medizintechnik und Technomathematik OPUS4-6720 Teil eines Buches Kirchner, Patrick, kirchner@fh-aachen.de; Reisert, Steffen, reisert@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de Calorimetric gas sensors for hydrogen peroxide monitoring in aseptic food processes For the sterilisation of aseptic food packages it is taken advantage of the microbicidal properties of hydrogen peroxide (H2O2). Especially, when applied in vapour phase, it has shown high potential of microbial inactivation. In addition, it offers a high environmental compatibility compared to other chemical sterilisation agents, as it decomposes into oxygen and water, respectively. Due to a lack in sensory detection possibilities, a continuous monitoring of the H2O2 concentration was recently not available. Instead, the sterilisation efficacy is validated using microbiological tests. However, progresses in the development of calorimetric gas sensors during the last 7 years have made it possible to monitor the H2O2 concentration during operation. This chapter deals with the fundamentals of calorimetric gas sensing with special focus on the detection of gaseous hydrogen peroxide. A sensor principle based on a calorimetric differential set-up is described. Special emphasis is given to the sensor design with respect to the operational requirements under field conditions. The state-of-the-art regarding a sensor set-up for the on-line monitoring and secondly, a miniaturised sensor for in-line monitoring are summarised. Furthermore, alternative detection methods and a novel multi-sensor system for the characterisation of aseptic sterilisation processes are described. Heidelberg Springer 2014 30 Gas sensing fundamentals. (Springer Series on Chemical Sensors and Biosensors ; 15) 978-3-642-54518-4 (Print) ; 978-3-642-54519-1 (Online) 279 309 10.1007/5346_2013_51 campus http://aachen.eblib.com/patron/FullRecord.aspx?p=1802738 INB - Institut für Nano- und Biotechnologien OPUS4-6721 Teil eines Buches Schöning, Michael Josef, schoening@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de; Glück, Olaf, ; Thust, Marion, Electrochemical methods for the determination of chemical variables in aqueous media Boca Raton, Fla. CRC Pr. 2014 NaN Measurement, instrumentation, and sensors handbook / ed. by John G. Webster [u.a.] Vol. 2 : Electromagnetic, optical, radiation, chemical, and biomedical measurement 978-1-4398-4891-3 55-1 55-54 Fachbereich Medizintechnik und Technomathematik OPUS4-6722 Wissenschaftlicher Artikel Bäcker, Matthias, baecker@fh-aachen.de; Schusser, Sebastian, schusser@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de Multi-Parametererfassung mit siliziumbasiertem Sensorchip: Aus Drei mach Eins Wiley 2014 2 GIT Labor-Fachzeitschrift 2 28 30 weltweit https://analyticalscience.wiley.com/do/10.1002/gitfach.11809/full/ Fachbereich Medizintechnik und Technomathematik OPUS4-6723 Konferenzveröffentlichung Huck, Christina, huck@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de; Buniatyan, V., ; Schöning, Michael Josef, schoening@fh-aachen.de Multi-parameter detection for supporting monitoring and control of biogas processes in agriculture Berlin VDE-Verl. 2014 1 CD-ROM Sensoren und Messsysteme 2014 ; Beiträge der 17. GMA/ITG-Fachtagung vom 3. bis 4. Juni 2014 in Nürnberg. (ITG-Fachbericht ; 250) 978-3-8007-3622-5 1 5 Fachbereich Medizintechnik und Technomathematik OPUS4-6724 Konferenzveröffentlichung Werner, Frederik, f.werner@fh-aachen.de; Yoshinobu, T., ; Miyamoto, K., ; Schöning, Michael Josef, schoening@fh-aachen.de; Wagner, Torsten, torsten.wagner@fh-aachen.de Semiconductor-based sensors for imaging of chemical processes Düsseldorf VDE-Verl. 2014 1 CD-ROM Sensoren und Messsysteme 2014 ; Beiträge der 17. GMA/ITG-Fachtagung vom 3. bis 4. Juni 2014 in Nürnberg. (ITG-Fachbericht ; 250) 978-3-8007-3622-5 1 5 Fachbereich Medizintechnik und Technomathematik OPUS4-6725 Konferenzveröffentlichung Wu, Chunsheng, c.wu@fh-aachen.de; Bronder, Thomas, bronder@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de DNA-hybridization detection using light-addressable potentiometric sensor modified with gold layer Düsseldorf VDE-Verl. 2014 1 CD-ROM Sensoren und Messsysteme 2014 ; Beiträge der 17. GMA/ITG-Fachtagung vom 3. bis 4. Juni 2014 in Nürnberg. (ITG-Fachbericht ; 250) 978-3-8007-3622-5 1 4 Fachbereich Medizintechnik und Technomathematik OPUS4-6726 Konferenzveröffentlichung Oberländer, Jan, oberlaender@fh-aachen.de; Kirchner, Patrick, kirchner@fh-aachen.de; Keusgen, M., ; Schöning, Michael Josef, schoening@fh-aachen.de Flexible polyimide-based calorimetric gas sensors for monitoring hy-drogen peroxide in sterilisation processes of aseptic filling machines Düsseldorf VDE-Verl. 2014 1 CD-ROM Sensoren und Messsysteme 2014 ; Beiträge der 17. GMA/ITG-Fachtagung vom 3. bis 4. Juni 2014 in Nürnberg. (ITG-Fachbericht ; 250) 978-3-8007-3622-5 1 4 Fachbereich Medizintechnik und Technomathematik OPUS4-6674 Wissenschaftlicher Artikel Siqueira, Jose R., ; Molinnus, Denise, molinnus@fh-aachen.de; Beging, Stefan, beging@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de Incorporating a hybrid urease-carbon nanotubes sensitive nanofilm on capacitive field-effect sensors for urea detection The ideal combination among biomolecules and nanomaterials is the key for reaching biosensing units with high sensitivity. The challenge, however, is to find out a stable and sensitive film architecture that can be incorporated on the sensor's surface. In this paper, we report on the benefits of incorporating a layer-by-layer (LbL) nanofilm of polyamidoamine (PAMAM) dendrimer and carbon nanotubes (CNTs) on capacitive electrolyte-insulator-semiconductor (EIS) field-effect sensors for detecting urea. Three sensor arrangements were studied in order to investigate the adequate film architecture, involving the LbL film with the enzyme urease: (i) urease immobilized directly onto a bare EIS [EIS-urease] sensor; (ii) urease atop the LbL film over the EIS [EIS-(PAMAM/CNT)-urease] sensor; and (iii) urease sandwiched between the LbL film and another CNT layer [EIS-(PAMAM/CNT)-urease-CNT]. The surface morphology of all three urea-based EIS biosensors was investigated by atomic force microscopy (AFM), while the biosensing abilities were studied by means of capacitance-voltage (C/V) and dynamic constant-capacitance (ConCap) measureaments at urea concentrations ranging from 0.1 mM to 100 mM. The EIS-urease and EIS-(PAMAM/CNT)-urease sensors showed similar sensitivity (∼18 mV/decade) and a nonregular signal behavior as the urea concentration increased. On the other hand, the EIS-(PAMAM/CNT)-urease-CNT sensor exhibited a superior output signal performance and higher sensitivity of about 33 mV/decade. The presence of the additional CNT layer was decisive to achieve a urea based EIS sensor with enhanced properties. Such sensitive architecture demonstrates that the incorporation of an adequate hybrid enzyme-nanofilm as sensing unit opens new prospects for biosensing applications using the field-effect sensor platform. Columbus ACS Publications 2014 5 Analytical chemistry 86 11 5370 5375 10.1021/ac500458s campus https://doi.org/10.1021/ac500458s Fachbereich Medizintechnik und Technomathematik OPUS4-6676 Wissenschaftlicher Artikel Murib, Mohammed Sharif, ; Yeap, Weng-Siang, ; Martens, Daan, ; Bienstman, Peter, ; Ceuninck, Ward de, ; Grinsven, Bart van, ; Schöning, Michael Josef, schoening@fh-aachen.de; Michiels, Luc, ; Haenen, Ken, ; Ameloot, Marcel, ; Serpengüzel, Ali, ; Wagner, Patrick, Photonic detection and characterization of DNA using sapphire microspheres A microcavity-based deoxyribonucleic acid (DNA) optical biosensor is demonstrated for the first time using synthetic sapphire for the optical cavity. Transmitted and elastic scattering intensity at 1510 nm are analyzed from a sapphire microsphere (radius 500  μm, refractive index 1.77) on an optical fiber half coupler. The 0.43 nm angular mode spacing of the resonances correlates well with the optical size of the sapphire sphere. Probe DNA consisting of a 36-mer fragment was covalently immobilized on a sapphire microsphere and hybridized with a 29-mer target DNA. Whispering gallery modes (WGMs) were monitored before the sapphire was functionalized with DNA and after it was functionalized with single-stranded DNA (ssDNA) and double-stranded DNA (dsDNA). The shift in WGMs from the surface modification with DNA was measured and correlated well with the estimated thickness of the add-on DNA layer. It is shown that ssDNA is more uniformly oriented on the sapphire surface than dsDNA. In addition, it is shown that functionalization of the sapphire spherical surface with DNA does not affect the quality factor (Q≈104) of the sapphire microspheres. The use of sapphire is especially interesting because this material is chemically resilient, biocompatible, and widely used for medical implants. Bellingham SPIE 2014 Journal of biomedical optics 19 9 097006 10.1117/1.JBO.19.9.097006 bezahl https://doi.org/10.1117/1.JBO.19.9.097006 Fachbereich Medizintechnik und Technomathematik OPUS4-6666 Wissenschaftlicher Artikel Yoshinobu, Tatsuo, ; Miyamoto, Ko-ichiro, ; Wagner, Torsten, torsten.wagner@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de Recent developments of chemical imaging sensor systems based on the principle of the light-addressable potentiometric sensor Amsterdam Elsevier 2015 6 Sensors and actuators B: Chemical 207 Part B 926 932 campus https://dx.doi.org/10.1016/j.snb.2014.09.002 Fachbereich Medizintechnik und Technomathematik OPUS4-6727 Konferenzveröffentlichung Bäcker, Matthias, baecker@fh-aachen.de; Schusser, Sebastian, schusser@fh-aachen.de; Leinhos, Marcel, leinhos@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de Sensor system for the monitoring of degradation processes of biodegradable biopolymers Düsseldorf VDE-Verl. 2014 1 CD-ROM Sensoren und Messsysteme 2014 ; Beiträge der 17. GMA/ITG-Fachtagung vom 3. bis 4. Juni 2014 in Nürnberg. (ITG-Fachbericht ; 250) 978-3-8007-3622-5 1 4 Fachbereich Medizintechnik und Technomathematik OPUS4-6729 Wissenschaftlicher Artikel Poghossian, Arshak, poghossian@fh-aachen.de; Bäcker, Matthias, baecker@fh-aachen.de; Mayer, Dirk, ; Schöning, Michael Josef, schoening@fh-aachen.de Gating capacitive field-effect sensors by the charge of nanoparticle/molecule hybrids Cambridge RSC Publication 2015 8 Nanoscale 7 1023 1031 bezahl http://dx.doi.org/10.1039/C4NR05987E Fachbereich Medizintechnik und Technomathematik OPUS4-6690 Wissenschaftlicher Artikel Schusser, Sebastian, schusser@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de; Bäcker, Matthias, baecker@fh-aachen.de; Krischer, M., ; Leinhos, Marcel, leinhos@fh-aachen.de; Wagner, P., ; Schöning, Michael Josef, schoening@fh-aachen.de An application of field-effect sensors for in-situ monitoring of degradation of biopolymers Amsterdam Elsevier 2015 5 Sensors and actuators B: Chemical 207 Part B 954 959 campus http://dx.doi.org/10.1016/j.snb.2014.10.058 Fachbereich Medizintechnik und Technomathematik OPUS4-104 Konferenzveröffentlichung Poghossian, Arshak, poghossian@fh-aachen.de; Schumacher, Kerstin, ; Kloock, Joachim P., kloock@fh-aachen.de; Rosenkranz, Christian, ; Schultze, Joachim W., ; Müller-Veggian, Mattea, mueller-veggian@opus.fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de Functional testing and characterisation of ISFETs on wafer level by means of a micro-droplet cell A wafer-level functionality testing and characterisation system for ISFETs (ionsensitive field-effect transistor) is realised by means of integration of a specifically designed capillary electrochemical micro-droplet cell into a commercial wafer prober-station. The developed system allows the identification and selection of "good" ISFETs at the earliest stage and to avoid expensive bonding, encapsulation and packaging processes for nonfunctioning ISFETs and thus, to decrease costs, which are wasted for bad dies. The developed system is also feasible for wafer-level characterisation of ISFETs in terms of sensitivity, hysteresis and response time. Additionally, the system might be also utilised for wafer-level testing of further electrochemical sensors. 2006 urn:nbn:de:hbz:a96-opus-1259 Fachbereich Medizintechnik und Technomathematik OPUS4-106 Konferenzveröffentlichung Wagner, Torsten, ; Schöning, Michael Josef, schoening@fh-aachen.de Preface of the Special Issue of I3S 2005 in Jülich (Germany) International Symposium on Sensor Science, I3S 2005 <3; 2005; Juelich, Germany> In: Sensors 2006, 6, 260-261 ISSN 1424-8220 2006 urn:nbn:de:hbz:a96-opus-1365 Fachbereich Medizintechnik und Technomathematik OPUS4-111 Konferenzveröffentlichung Näther, Niko, naether@fh-aachen.de; Juárez, Leon M., ; Emmerich, Rüdiger, ; Berger, Jörg, ; Friedrich, Peter, ; Schöning, Michael Josef, schoening@fh-aachen.de Detection of hydrogen peroxide (H2O2) at exposed temperatures for industrial processes An H2O2 sensor for the application in industrial sterilisation processes has been developed. Therefore, automated sterilisation equipment at laboratory scale has been constructed using parts from industrial sterilisation facilities. In addition, a software tool has been developed for the control of the sterilisation equipment at laboratory scale. First measurements with the developed sensor set-up as part of the sterilisation equipment have been performed and the sensor has been physically characterised by optical microscopy and SEM. 2006 urn:nbn:de:hbz:a96-opus-1418 Fachbereich Medizintechnik und Technomathematik OPUS4-117 Konferenzveröffentlichung Platen, Johannes, ; Poghossian, Arshak, poghossian@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de Microstructured Nanostructures - nanostructuring by means of conventional photolithography and layer-expansion technique A new and simple method for nanostructuring using conventional photolithography and layer expansion or pattern-size reduction technique is presented, which can further be applied for the fabrication of different nanostructures and nano-devices. The method is based on the conversion of a photolithographically patterned metal layer to a metal-oxide mask with improved pattern-size resolution using thermal oxidation. With this technique, the pattern size can be scaled down to several nanometer dimensions. The proposed method is experimentally demonstrated by preparing nanostructures with different configurations and layouts, like circles, rectangles, trapezoids, "fluidic-channel"-, "cantilever"- and meander-type structures. 2006 urn:nbn:de:hbz:a96-opus-1477 Fachbereich Medizintechnik und Technomathematik OPUS4-124 Konferenzveröffentlichung Arida, Hassan A., ; Kloock, Joachim P., kloock@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de Novel organic membrane-based thin-film microsensors for the determination of heavy metal cations A first step towards the fabrication and electrochemical evaluation of thin-film microsensors based on organic PVC membranes for the determination of Hg(II), Cd(II), Pb(II) and Cu(II) ions in solutions has been realised. The membrane-coating mixture used in the preparation of this new type of microsensors is incorporating PVC as supporting matrix, o-nitrophenyloctylether (o-NPOE) as solvent mediator and a recently synthesized Hg[dimethylglyoxime(phene)]2+ and Bis-(4-hydroxyacetophenone)-ethylenediamine as electroactive materials for Hg(II) and Cd(II), respectively. A set of three commercialised ionophores for Cd(II), Pb(II) and Cu(II) has been also used for comparison. Thin-film microsensors based on these membranes showed a Nernstian response of slope (26-30 mV/dec.) for the respective tested cations. The potentiometric response characteristics (linear range, pH range, detection limit and response time) are comparable with those obtained by conventional membranes as well as coated wire electrodes prepared from the same membrane. The realisation of the new organic membrane-based thin-film microsensors overcomes the problem of an insufficient selectivity of solid-state-based thinfilm sensors. 2006 urn:nbn:de:hbz:a96-opus-1545 Fachbereich Medizintechnik und Technomathematik OPUS4-6812 Wissenschaftlicher Artikel Guo, Yuanyuan, ; Seki, Kosuke, ; Miyamoto, Ko-ichiro, ; Wagner, Torsten, torsten.wagner@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de; Yoshinobu, Tatsuo, Device simulation of the light-addressable potentiometric sensor with a novel photoexcitation method for a higher spatial resolution A novel photoexcitation method for the light-addressable potentiometric sensor (LAPS) realized a higher spatial resolution of chemical imaging. In this method, a modulated light probe, which generates the alternating photocurrent signal, is surrounded by a ring of constant light, which suppresses the lateral diffusion of photocarriers by enhancing recombination. A device simulation verified that a higher spatial resolution could be obtained by adjusting the gap between the modulated and constant light. It was also found that a higher intensity and a longer wavelength of constant light was more effective. However, there exists a tradeoff between the spatial resolution and the amplitude of the photocurrent, and thus, the signal-to-noise ratio. A tilted incidence of constant light was applied, which could achieve even higher resolution with a smaller loss of photocurrent. Amsterdam Elsevier 2014 3 Procedia Engineering 87 EUROSENSORS 2014 ; European Conference on Solid-State Transducers <28, 2014> 456 459 10.1016/j.proeng.2014.11.369 weltweit https://doi.org/10.1016/j.proeng.2014.11.369 Fachbereich Medizintechnik und Technomathematik OPUS4-6813 Wissenschaftlicher Artikel Miyamoto, K., ; Seki, K., ; Wagner, Torsten, torsten.wagner@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de; Yoshinobu, T., Enhancement of the spatial resolution of the chemical imaging sensor by a hybrid fiber-optic illumination The chemical imaging sensor, which is based on the principle of the light-addressable potentiometric sensor (LAPS), is a powerful tool to visualize the spatial distribution of chemical species on the sensor surface. The spatial resolution of this sensor depends on the diffusion of photocarriers excited by a modulated light. In this study, a novel hybrid fiber-optic illumination was developed to enhance the spatial resolution. It consists of a modulated light probe to generate a photocurrent signal and a ring of constant light, which suppresses the lateral diffusion of minority carriers excited by the modulated light. It is demonstrated that the spatial resolution was improved from 92 μm to 68 μm. Amsterdam Elsevier 2014 3 Procedia Engineering 87 EUROSENSORS 2014 ; European Conference on Solid-State Transducers <28, 2014> 612 615 10.1016/j.proeng.2014.11.563 weltweit https://doi.org/10.1016/j.proeng.2014.11.563 Fachbereich Medizintechnik und Technomathematik OPUS4-6814 Wissenschaftlicher Artikel Bronder, Thomas, bronder@fh-aachen.de; Wu, Chunsheng, C.Wu@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de; Werner, Frederik, f.werner@fh-aachen.de; Keusgen, M., ; Schöning, Michael Josef, schoening@fh-aachen.de Label-free detection of DNA hybridization with light-addressable potentiometric sensors: comparison of various DNA-immobilization strategies Light-addressable potentiometric sensors (LAPS) consisting of a p-Si-SiO2 and p-Si-SiO2-Au structure, respectively, have been tested for a label-free electrical detection of DNA (deoxyribonucleic acid) hybridization. Three different strategies for immobilizing single-stranded probe DNA (ssDNA) molecules on a LAPS surface have been studied and compared: (a) immobilization of thiol-modified ssDNA on the patterned Au surface via gold-thiol bond, (b) covalent immobilization of amino-modified ssDNA onto the SiO2 surface functionalized with 3-aminopropyltriethoxysilane and (c) layer-by-layer adsorption of negatively charged ssDNA on a positively charged weak polyelectrolyte layer of poly(allylamine hydrochloride). Amsterdam Elsevier 2014 3 Procedia Engineering 87 EUROSENSORS 2014 ; European Conference on Solid-State Transducers <28, 2014> 755 758 10.1016/j.proeng.2014.11.647 weltweit https://doi.org/10.1016/j.proeng.2014.11.647 Fachbereich Medizintechnik und Technomathematik OPUS4-6815 Wissenschaftlicher Artikel Huck, Christina, huck@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de; Bäcker, Matthias, baecker@fh-aachen.de; Reisert, Steffen, reisert@fh-aachen.de; Schubert, J., ; Zander, W., ; Begoyan, V. K., ; Buniatyan, V. V., ; Schöning, Michael Josef, schoening@fh-aachen.de Chemical sensors based on a high-k perovskite oxide of barium strontium titanate High-k perovskite oxide of barium strontium titanate (BST) represents a very attractive multi-functional transducer material for the development of (bio-)chemical sensors for liquids. In this work, BST films have been applied as a sensitive transducer material for a label-free detection of adsorbed charged macromolecules (positively charged polyelectrolytes) and concentration of hydrogen peroxide vapor as well as protection insulator layer for a contactless electrolyte-conductivity sensor. The experimental results of characterization of individual sensors are presented. Special emphasis is devoted towards the development of a capacitively-coupled contactless electrolyte-conductivity sensor. Amsterdam Elsevier 2014 3 Procedia Engineering 87 EUROSENSORS 2014 ; European Conference on Solid-State Transducers <28, 2014> 28 31 10.1016/j.proeng.2014.11.258 weltweit https://doi.org/10.1016/j.proeng.2014.11.258 Fachbereich Medizintechnik und Technomathematik OPUS4-6816 Wissenschaftlicher Artikel Schusser, Sebastian, schusser@fh-aachen.de; Bäcker, Matthias, baecker@fh-aachen.de; Krischer, M., ; Wenzel, L., ; Leinhos, Marcel, leinhos@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de; Biselli, Manfred, biselli@fh-aachen.de; Wagner, P., ; Schöning, Michael Josef, schoening@fh-aachen.de Enzymatically catalyzed degradation of biodegradable polymers investigated by means of a semiconductor-based field-effect sensor A semiconductor field-effect device has been used for an enzymatically catalyzed degradation of biopolymers for the first time. This novel technique is capable to monitor the degradation process of multiple samples in situ and in real-time. As model system, the degradation of the biopolymer poly(D, L-lactic acid) has been monitored in the degradation medium containing the enzyme lipase from Rhizomucor miehei. The obtained results demonstrate the potential of capacitive field-effect sensors for degradation studies of biodegradable polymers. Amsterdam Elsevier 2014 3 Procedia Engineering 87 EUROSENSORS 2014 ; European Conference on Solid-State Transducers <28, 2014> 1314 1317 10.1016/j.proeng.2014.11.689 weltweit https://doi.org/10.1016/j.proeng.2014.11.689 Fachbereich Medizintechnik und Technomathematik OPUS4-6779 Wissenschaftlicher Artikel Murib, M. S., ; Yeap, W. S., ; Martens, D., ; Liu, X., ; Bienstman, P., ; Fahlman, M., ; Schöning, Michael Josef, schoening@fh-aachen.de; Michiels, L., ; Haenen, K., ; Serpengüzel, A., ; Wagner, Patrick, Photonic studies on polymer-coated sapphire-spheres : a model system for biological ligands Amsterdam Elsevier 2015 7 Sensors and actuators A: Physical 222 212 219 campus http://dx.doi.org/10.1016/j.sna.2014.11.024 Fachbereich Medizintechnik und Technomathematik OPUS4-6823 Konferenzveröffentlichung Kloock, Joachim P., kloock@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de Heavy metal detection with semiconductor devices based on PLD-prepared chalcogenide glass thin films 2007 3 Armenian Journal of Physics Proceedings of the 6th International Conference on Semiconductor Micro- and Nanoelectronics, Tsakhadzor (Armenia) 18-20 September 2007 95 98 weltweit http://ajp.asj-oa.am/15/2/7.pdf Fachbereich Medizintechnik und Technomathematik OPUS4-6825 Konferenzveröffentlichung Wagner, Torsten, torsten.wagner@fh-aachen.de; Yoshinobu, T., ; Schöning, Michael Josef, schoening@fh-aachen.de Light-addressable potentiometric sensor as semiconductor-based sensor platform for (bio-) chemical sensing 2008 4 Armenian Journal of Physics Proceedings of the 6th International Conference on Semiconductor Micro- and Nanoelectronics, Tsakhadzor (Armenia) 18-20 September 2007 99 103 weltweit http://ajp.asj-oa.am/20/1/12.pdf Fachbereich Medizintechnik und Technomathematik OPUS4-6827 Wissenschaftlicher Artikel Schütz, S., ; Weißbecker, B., ; Hummel, Hans E., ; Schöning, Michael Josef, schoening@fh-aachen.de; Riemer, A., ; Kordos, P., ; Lüth, H., Field effect transistor-insect antenna junction 1997 2 Naturwissenschaften 84 86 88 campus http://link.springer.com/article/10.1007%2Fs001140050355 Fachbereich Medizintechnik und Technomathematik OPUS4-6828 Wissenschaftlicher Artikel Thust, Marion, ; Schöning, Michael Josef, schoening@fh-aachen.de; Frohnhoff, S., ; Arens-Fischer, R., ; Kordos, P., ; Lüth, H., Porous silicon as a substrate material for potentiometric biosensors 1996 3 Measurement Science and Technology 7 1 26 29 10.1088/0957-0233/7/1/003 campus Fachbereich Medizintechnik und Technomathematik OPUS4-6831 Konferenzveröffentlichung Weil, M., ; Poghossian, Arshak, poghossian@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de; Cherstvy, A., Electrical monitoring of layer-by-layer adsorption of oppositely charged macromolecules by means of capacitive field-effect devices 2012 3 978-3-9813484-2-2 14th International Meeting on Chemical Sensors - IMCS 2012 1575 1578 10.5162/IMCS2012/P2.5.2 weltweit Fachbereich Medizintechnik und Technomathematik OPUS4-6832 Konferenzveröffentlichung Bohrn, Ulrich, ; Mucha, Andreas, ; Werner, Frederik, f.werner@fh-aachen.de; Stütz, Evamaria, ; Bäcker, Matthias, baecker@fh-aachen.de; Krumbe, Christoph, ; Schienle, Meinrad, ; Fleischer, Maximilian, ; Wagner, Patrick, ; Schöning, Michael Josef, schoening@fh-aachen.de Detection of toxic chromium species in water using cellbased sensor systems 2012 3 978-3-9813484-2-2 14th International Meeting on Chemical Sensors - IMCS 2012 1364 1367 10.5162/IMCS2012/P2.1.14 weltweit Fachbereich Medizintechnik und Technomathematik OPUS4-6848 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Bäcker, Matthias, baecker@fh-aachen.de Chip-basierte Sensoren für die Biotechnik Berlin BIOCOM 2012 13 4 Seiten 2 weltweit nicht mehr abrufbar Fachbereich Medizintechnik und Technomathematik OPUS4-6849 Wissenschaftlicher Artikel Wagner, Torsten, torsten.wagner@fh-aachen.de; Miyamoto, K., ; Werner, Frederik, f.werner@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de; Yoshinobu, T., Utilising Digital Micro-Mirror Device (DMD) as Scanning Light Source for Light-Addressable Potentiometric Sensors (LAPS) Stevenson Ranch, Calif. American Scientific Publishers 2011 3 9 2 812 815 10.1166/sl.2011.1620 bezahl Fachbereich Medizintechnik und Technomathematik OPUS4-6850 Konferenzveröffentlichung Schöning, Michael Josef, schoening@fh-aachen.de; Abouzar, Maryam H., ; Wagner, Torsten, torsten.wagner@fh-aachen.de; Näther, Niko, naether@fh-aachen.de; Rolka, David, d.rolka@fh-aachen.de; Yoshinobu, Tatsuo, ; Kloock, Joachim P., kloock@fh-aachen.de; Turek, Monika, ; Ingebrandt, Sven, ; Poghossian, Arshak, poghossian@fh-aachen.de A semiconductor-based field-effect platform for (bio-)chemical and physical sensors: From capacitive EIS sensors and LAPS over ISFETs to nano-scale devices 2006 8 MRS Proceedings Vol. 952 - Symposium F - Integrated Nanosensors 1 9 10.1557/PROC-0952-F08-02 bezahl Fachbereich Medizintechnik und Technomathematik OPUS4-6852 Konferenzveröffentlichung Moritz, Werner, ; Yoshinobu, Tatsuo, ; Finger, Friedhelm, ; Krause, Steffi, ; Schöning, Michael Josef, schoening@fh-aachen.de Amorphous silicon as semiconductor material for high resolution LAPS 2003 1 Eurosensors XVII : the 17th European Conference on Solid-State Transducers ; University of Minho, Guimarães, Portugal, September 21 - 24, 2003 Eurosensors <17, 2003, Guimarães> 48 49 weltweit http://repositorium.sdum.uminho.pt/bitstream/1822/4837/1/BookOfAbstractsFinal.pdf Fachbereich Medizintechnik und Technomathematik OPUS4-6853 Konferenzveröffentlichung Ermelenko, Y., ; Yoshinobu, T., ; Mourzina, Y., ; Schöning, Michael Josef, schoening@fh-aachen.de; Vlasov, Y., ; Iwasaki, H., A multisensor based on laser scanned silicon transducer (LSST): development and properties 2003 1 Eurosensors XVII : the 17th European Conference on Solid-State Transducers ; University of Minho, Guimarães, Portugal, September 21 - 24, 2003 Eurosensors <17, 2003, Guimarães> 72 73 weltweit http://repositorium.sdum.uminho.pt/bitstream/1822/4837/1/BookOfAbstractsFinal.pdf Fachbereich Medizintechnik und Technomathematik OPUS4-6835 Konferenzveröffentlichung Bohrn, Ulrich, ; Stütz, Evamaria, ; Fleischer, Maximilian, ; Schöning, Michael Josef, schoening@fh-aachen.de; Wagner, Patrick, Living cell-based gas sensor system for the detection of acetone in air 2012 3 978-3-9813484-2-2 14th International Meeting on Chemical Sensors - IMCS 2012 269 272 10.5162/IMCS2012/3.2.3 weltweit Fachbereich Medizintechnik und Technomathematik OPUS4-6836 Konferenzveröffentlichung Takenaga, Shoko, ; Werner, Frederik, f.werner@fh-aachen.de; Sawada, Kazuaki, ; Schöning, Michael Josef, schoening@fh-aachen.de Comparison of label-free ACh image sensors based on CCD and LAPS 2012 3 978-3-9813484-2-2 14th International Meeting on Chemical Sensors - IMCS 2012 356 359 10.5162/IMCS2012/4.2.6 weltweit Fachbereich Medizintechnik und Technomathematik OPUS4-6837 Konferenzveröffentlichung Huck, Christina, huck@fh-aachen.de; Bäcker, Matthias, baecker@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de; Wagner, Patrick, ; Schöning, Michael Josef, schoening@fh-aachen.de Bifunktionaler Sensorchip für den Nachweis von Gelöstwasserstoff 2011 3 978-3942710-53-4 10. Dresdner Sensor-Symposium 2011 325 328 10.5162/10dss2011/16.10 weltweit Fachbereich Medizintechnik und Technomathematik OPUS4-6838 Konferenzveröffentlichung Kloock, Joachim P., kloock@fh-aachen.de; Moreno, Lia, ; Huachupoma, S., ; Xu, J., ; Wagner, Torsten, torsten.wagner@fh-aachen.de; Bratov, A., ; Doll, T., ; Vlasov, Y., ; Schöning, Michael Josef, schoening@fh-aachen.de Gerlach, Gerald Halbleiterbasierte Schwermetallsensorik auf der Basis von Chalkogenidgläsern für zukünftige „Lab on Chip"-Anwendungen Dresden TUDpress, Verl. der Wissenschaften 2005 3 7. Dresdner Sensor-Symposium - Neue Herausforderungen und Anwendungen in der Sensortechnik 3-938863-29-3 Dresdner Beiträge zur Sensorik ; 24 Dresdner Sensor-Symposium <7, 2005, Dresden> 221 224 Fachbereich Medizintechnik und Technomathematik OPUS4-6839 Konferenzveröffentlichung Schöning, Michael Josef, schoening@fh-aachen.de; Abouzar, Maryam H., ; Han, Y., ; Ingebrandt, S., ; Offenhäusser, A., ; Poghossian, Arshak, poghossian@fh-aachen.de Markierungsfreie DNA-Detektion mit Silizium-Feldeffektsensoren - Messeffekte oder Artefakte? Berlin VDE Verl. 2006 630 S., + 1 CD-ROM Sensoren und Mess-Systeme 2006 : Vorträge der 13. ITG/GMA-Fachtagung vom 13. bis 14.3.2006 in Freiburg/Breisgau 3-8007-2939-3 443 446 Fachbereich Medizintechnik und Technomathematik OPUS4-6840 Konferenzveröffentlichung Platen, J., ; Poghossian, Arshak, poghossian@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de Präparation von selbstjustierenden Nanostrukturen mittels Schichtausdehnungstechnik Berlin VDE Verl. 2006 630 S., + 1 CD-ROM Sensoren und Mess-Systeme 2006 : Vorträge der 13. ITG/GMA-Fachtagung vom 13. bis 14.3.2006 in Freiburg/Breisgau 3-8007-2939-3 277 280 Fachbereich Medizintechnik und Technomathematik OPUS4-6841 Konferenzveröffentlichung Wagner, Torsten, torsten.wagner@fh-aachen.de; Yoshinobu, T., ; Otto, R., ; Rao, C., ; Molina, R., ; Schöning, Michael Josef, schoening@fh-aachen.de Licht-adressierbare potentiometrische Sensorsysteme - Konzepte und Anwendungen Berlin VDE Verl. 2006 630 S., + 1 CD-ROM Sensoren und Mess-Systeme 2006 : Vorträge der 13. ITG/GMA-Fachtagung vom 13. bis 14.3.2006 in Freiburg/Breisgau 3-8007-2939-3 165 168 Fachbereich Medizintechnik und Technomathematik OPUS4-6842 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de BioFEDs (field-effect devices) : State-of-the-art and new directions 2006 7 Electroanalysis 18 19-20 1893 1900 10.1002/elan.200603609 campus Fachbereich Medizintechnik und Technomathematik OPUS4-6843 Wissenschaftlicher Artikel Spelthahn, Heiko, ; Schubert, Jürgen, ; Schöning, Michael Josef, schoening@fh-aachen.de Dünnschichtsensoren für die Schwermetallanalytik : Mikroelektroden auf Chalkogenidglasbasis Die Detektion von Schadstoffen repräsentiert in der Umweltanalytik eine wichtige Aufgabenstellung. Gerade die Abwasser- bzw. Brauchwasseranalytik sowie die Prozesskontrolle haben einen hohen Stellenwert. Siliziumbasierte Dünnschichtsensoren bieten eine kostengünstige Möglichkeit, „online"-Messungen bzw. Vor-Ort-Messungen zeitnah durchzuführen. In dieser Arbeit wird ein potentiometrisches Sensorarray auf der Basis von Chalkogenidgläsern zur Detektion von Schwermetallen in wässrigen Medien vorgestellt. Weinheim Wiley-VCH 2012 2 GIT Labor-Fachzeitschrift 4 285 287 weltweit http://www.git-labor.de/forschung/umwelt/duennschichtsensoren-fuer-die-schwermetallanalytik?page=1 Fachbereich Medizintechnik und Technomathematik OPUS4-6854 Konferenzveröffentlichung Yoshinobu, T., ; Schöning, Michael Josef, schoening@fh-aachen.de; Finger, F., ; Moritz, W., ; Iwasaki, H., Thin-film a-Si LAPS : Preparation and pH sensitivity 2003 1 Eurosensors XVII : the 17th European Conference on Solid-State Transducers ; University of Minho, Guimarães, Portugal, September 21 - 24, 2003 Eurosensors <17, 2003, Guimarães> 88 89 weltweit http://repositorium.sdum.uminho.pt/bitstream/1822/4837/1/BookOfAbstractsFinal.pdf Fachbereich Medizintechnik und Technomathematik OPUS4-6855 Konferenzveröffentlichung Näther, Niko, naether@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de; Platen, J., ; Yoshinobu, T., ; Koudelka-Hep, M., ; Schöning, Michael Josef, schoening@fh-aachen.de Multi-parameter sensing of both physical and (bio-)chemical quantities using the same transducer principle Warsaw 2006 9 Biochemical sensing utilisation of micro- and nanotechnologies : Warsaw, [23rd - 26th] November 2005 / ed. by M. Mascini ... Lecture notes of the ICB seminars ; 73 172 181 Fachbereich Medizintechnik und Technomathematik OPUS4-6856 Konferenzveröffentlichung Kloock, Joachim P., kloock@fh-aachen.de; Schubert, J., ; Ermelenko, Y., ; Vlasov, Y. G., ; Bratov, A., ; Schöning, Michael Josef, schoening@fh-aachen.de Thin-film sensors with chalcogenide glass materials - a general survey Warsaw 2006 5 Biochemical sensing utilisation of micro- and nanotechnologies : Warsaw, [23rd - 26th] November 2005 / ed. by M. Mascini ... Lecture notes of the ICB seminars ; 73 92 97 Fachbereich Medizintechnik und Technomathematik OPUS4-6857 Konferenzveröffentlichung Beging, Stefan, beging@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de; Mlynek, D., ; Hataihimakul, S., ; Pedraza, A., ; Dhawan, S., ; Laube, N., ; Kleinen, L., ; Baldsiefen, G., ; Busch, H., ; Schöning, Michael Josef, schoening@fh-aachen.de Ion-selective sensors for the determination of the risk of urinary stone formation Warsaw 2010 6 Micro- and Nanosystems in biochemical diagnosis : Principles and applications Lecture Notes of the ICB Seminar 74 80 Fachbereich Medizintechnik und Technomathematik OPUS4-6975 Teil eines Buches Poghossian, Arshak, poghossian@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de Silicon-based chemical and biological field-effect sensors Stevenson Ranch, Calif. ASP, American Scientific Publ. 2006 71 Encyclopedia of Sensors. Vol. 9 S - Sk 1-58883-065-9 463 534 Fachbereich Medizintechnik und Technomathematik OPUS4-7040 Konferenzveröffentlichung Moreno, Lia, ; Dosev, D., ; Bratov, A., ; Dominguez, C., ; Schöning, Michael Josef, schoening@fh-aachen.de; Kloock, Joachim P., kloock@fh-aachen.de Effect of electrical properties of the surrounding medium on the response of an interdigitated electrode array with chalcogenide glass film Göteborg 2006 1 XX Eurosensors : 20th anniversary ; Göteborg, Sweden, 17 - 20 September 2006 ; [proceedings]. - Vol. 1 978-91-631-9280-7 Paper number: T1A-P22 384 385 Fachbereich Medizintechnik und Technomathematik OPUS4-7046 Wissenschaftlicher Artikel Wu, Chunsheng, C.Wu@fh-aachen.de; Bronder, Thomas, bronder@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de; Werner, Frederik, f.werner@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de Label-free detection of DNA using light-addressable potentiometric sensor modified with a positively charged polyelectrolyte layer 2015 7 Nanoscale 7 6143 6150 10.1039/C4NR07225A Fachbereich Medizintechnik und Technomathematik OPUS4-7047 Wissenschaftlicher Artikel Beging, Stefan, beging@fh-aachen.de; Leinhos, Marcel, leinhos@fh-aachen.de; Jablonski, Melanie, ; Poghossian, Arshak, poghossian@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de Studying the spatially resolved immobilisation of enzymes on a capacitive field-effect structure by means of nano-spotting Weinheim Wiley 2015 5 Physica status solidi (a) 212 6 1353 1358 10.1002/pssa.201431891 Fachbereich Medizintechnik und Technomathematik OPUS4-7049 Wissenschaftlicher Artikel Poghossian, Arshak, poghossian@fh-aachen.de; Katz, Evgeny, ; Schöning, Michael Josef, schoening@fh-aachen.de Enzyme logic AND-Reset and OR-Reset gates based on a field-effect electronic transducer modified with multi-enzyme membrane 2015 3 Chemical Communications 51 6564 6567 10.1039/C5CC01362C Fachbereich Medizintechnik und Technomathematik OPUS4-7005 Konferenzveröffentlichung Kirchner, Patrick, ; Henkel, H., ; Näther, Niko, naether@fh-aachen.de; Spelthahn, H., ; Schneider, A., ; Berger, J., ; Kolstad, J., ; Friedrich, P., ; Schöning, Michael Josef, schoening@fh-aachen.de RFID-basiertes Sensorsystem zur Realisierung intelligenter Verpackungen für die Nahrungsmittelindustrie Berlin BMBF 2008 9 S. KMU - innovativ: IKT 2008. CD-ROM : BMBF-Statustagung KMU - innovativ: IKT, Darmstadt, 17. - 18. Nov. 2008 CD-ROM-Ausg. Fachbereich Medizintechnik und Technomathematik OPUS4-7076 Wissenschaftlicher Artikel Huck, Christina, huck@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de; Bäcker, Matthias, baecker@fh-aachen.de; Reisert, Steffen, reisert@fh-aachen.de; Kramer, Friederike, ; Begoyan, Vardges K., ; Buniatyan, Vahe V., ; Schöning, Michael Josef, schoening@fh-aachen.de Multi-parameter sensing using high-k oxide of barium strontium titanate Weinheim Wiley 2015 1254 Physica status solidi (a) 212 6 1259 10.1002/pssa.201431911 Fachbereich Medizintechnik und Technomathematik OPUS4-7077 Wissenschaftlicher Artikel Jildeh, Zaid B., ; Wagner, Torsten, torsten.wagner@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de; Pieper, Martin, pieper@fh-aachen.de Simulating the electromagnetic-thermal treatment of thin aluminium layers for adhesion improvement Weinheim Wiley 2015 7 Physica status solidi (a) Vol. 212 6 1234 1241 10.1002/pssa.201431893 Fachbereich Medizintechnik und Technomathematik OPUS4-7091 Wissenschaftlicher Artikel Breuer, Lars, L.Breuer@fh-aachen.de; Raue, Markus, raue@fh-aachen.de; Kirschbaum, M., ; Mang, Thomas, mang@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de; Thoelen, R., ; Wagner, Torsten, torsten.wagner@fh-aachen.de Light-controllable polymeric material based on temperature-sensitive hydrogels with incorporated graphene oxide Weinheim Wiley 2015 6 Physica status solidi (a) 212 6 1368 1374 10.1002/pssa.201431944 Fachbereich Chemie und Biotechnologie OPUS4-7294 Wissenschaftlicher Artikel Delle, Lotta E., ; Huck, Christina, huck@fh-aachen.de; Bäcker, Matthias, baecker@fh-aachen.de; Müller, Frank, ; Grandthyll, Samuel, ; Jacobs, Karin, ; Lilischkis, Rainer, ; Vu, Xuan T., ; Schöning, Michael Josef, schoening@fh-aachen.de; Wagner, Patrick, ; Thoelen, Roland, ; Weil, Maryam, ; Ingebrandt, Sven, Impedimetric immunosensor for the detection of histamine based on reduced graphene oxide Weinheim Wiley 2015 7 Physica status solidi (a) 212 6 1327 1334 10.1002/pssa.201431863 campus https://doi.org/10.1002/pssa.201431863 Fachbereich Medizintechnik und Technomathematik OPUS4-7332 Wissenschaftlicher Artikel Dantism, S., ; Takenaga, S., ; Wagner, P., ; Wagner, Torsten, torsten.wagner@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de Light-addressable Potentiometric Sensor (LAPS) Combined with Multi-chamber Structures to Investigate the Metabolic Activity of Cells Amsterdam Elsevier 2015 3 Procedia Engineering 120 Eurosensors 2015 384 387 10.1016/j.proeng.2015.08.647 Fachbereich Medizintechnik und Technomathematik OPUS4-7333 Wissenschaftlicher Artikel Molinnus, Denise, molinnus@fh-aachen.de; Bäcker, Matthias, baecker@fh-aachen.de; Siegert, Petra, siegert@fh-aachen.de; Willenberg, H., ; Poghossian, Arshak, poghossian@fh-aachen.de; Keusgen, M., ; Schöning, Michael Josef, schoening@fh-aachen.de Detection of Adrenaline Based on Substrate Recycling Amplification Amsterdam Elsevier 2015 3 Procedia Engineering 120 Eurosensors 2015 540 543 10.1016/j.proeng.2015.08.708 https://doi.org/10.1016/j.proeng.2015.08.708 Fachbereich Chemie und Biotechnologie OPUS4-7334 Wissenschaftlicher Artikel Schusser, Sebastian, schusser@fh-aachen.de; Krischer, M., ; Molin, D. G. M., ; Akker, N. M. S. van den, ; Bäcker, Matthias, baecker@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de Sensor System for in-situ and Real-time Monitoring of Polymer (bio) degradation Amsterdam Elsevier 2015 3 Procedia Engineering 120 Eurosensors 2015 948 951 10.1016/j.proeng.2015.08.815 Fachbereich Medizintechnik und Technomathematik OPUS4-7336 Wissenschaftlicher Artikel Pilas, Johanna, pilas@fh-aachen.de; Mariano, K., ; Keusgen, M., ; Selmer, Thorsten, selmer@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de Optimization of an Enzyme-based Multi-parameter Biosensor for Monitoring Biogas Processes Amsterdam Elsevier 2015 3 Procedia Engineering 120 Eurosensors 2015 532 535 10.1016/j.proeng.2015.08.702 Fachbereich Chemie und Biotechnologie OPUS4-7337 Wissenschaftlicher Artikel Miyamoto, Ko-ichiro, ; Bing, Yu, ; Wagner, Torsten, torsten.wagner@fh-aachen.de; Yoshinobu, Tatsuo, ; Schöning, Michael Josef, schoening@fh-aachen.de Visualization of Defects on a Cultured Cell Layer by Utilizing Chemical Imaging Sensor Amsterdam Elsevier 2015 3 Procedia Engineering 120 Eurosensors 2015 936 939 10.1016/j.proeng.2015.08.806 Fachbereich Medizintechnik und Technomathematik OPUS4-7287 Konferenzveröffentlichung Poghossian, Arshak, poghossian@fh-aachen.de; Ingebrandt, S., ; Platen, J., ; Schöning, Michael Josef, schoening@fh-aachen.de Field-effect sensors with charged macromolecules - from micro towards nano aspects Warsaw Polish Academy Sciences Press 2006 7 Biochemical Sensing Utilisation of Micro-and Nanotechnologies, Warschau, Nov. 2005 : Lecture Notes of the ICB Seminar / ed.: M. Mascini, W. Torbicz 74 81 Fachbereich Medizintechnik und Technomathematik OPUS4-7288 Wissenschaftlicher Artikel Yoshinobu, Tatsuo, ; Moritz, Werner, ; Finger, Friedhelm, ; Schöning, Michael Josef, schoening@fh-aachen.de Comini, Elisabetta Application of thin-film amorphous silicon to chemical imaging 2006 9 Nanostructured materials and hybrid composites for gas sensors and biomedical applications : symposium held April 18-20, 2006, San Francisco , California, U.S.A. 9781558998711 Materials Research Society symposia proceedings; v. 915 Paper 0910-A-20-01 1 10 Fachbereich Medizintechnik und Technomathematik OPUS4-7289 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Abouzar, Maryam H., ; Ingebrandt, Sven, ; Platen, Johannes, ; Offenhäusser, Andreas, ; Poghossian, Arshak, poghossian@fh-aachen.de Comini, Elisabetta Towards label-free detection of charged macromolecules using field-effect-based structures : Scaling down from capacitive EIS sensor over ISFET to nano-scale devices 2006 5 Nanostructured materials and hybrid composites for gas sensors and biomedical applications : symposium held April 18-20, 2006, San Francisco , California, U.S.A. 9781558998711 Materials Research Society symposia proceedings; v. 915 paper 0915-R05-04 89 94 Fachbereich Medizintechnik und Technomathematik OPUS4-7291 Wissenschaftlicher Artikel Takenaga, Shoko, takenaga@fh-aachen.de; Schneider, Benno, benno.schneider@fh-aachen.de; Erbay, E., ; Biselli, Manfred, biselli@fh-aachen.de; Schnitzler, Thomas, schnitzler@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de; Wagner, Torsten, torsten.wagner@fh-aachen.de Fabrication of biocompatible lab-on-chip devices for biomedical applications by means of a 3D-printing process Weinheim Wiley 2015 5 Physica status solidi (a) 212 6 1347 1352 10.1002/pssa.201532053 Fachbereich Chemie und Biotechnologie OPUS4-7293 Wissenschaftlicher Artikel Warmer, Johannes, ; Wagner, Patrick, ; Schöning, Michael Josef, schoening@fh-aachen.de; Kaul, Peter, Detection of triacetone triperoxide using temperature cycled metal-oxide semiconductor gas sensors Weinheim Wiley-VCH 2015 9 Physica status solidi (a) 212 6 1289 1298 10.1002/pssa.201431882 campus https://doi.org/10.1002/pssa.201431882 Fachbereich Medizintechnik und Technomathematik OPUS4-7338 Wissenschaftlicher Artikel Bronder, Thomas, bronder@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de; Scheja, S., ; Wu, Chunsheng, C.Wu@fh-aachen.de; Keusgen, M., ; Schöning, Michael Josef, schoening@fh-aachen.de Electrostatic Detection of Unlabelled Single- and Double-stranded DNA Using Capacitive Field-effect Devices Functionalized with a Positively Charged Polyelectrolyte Layer Amsterdam Elsevier 2015 3 Procedia Engineering 120 Eurosensors 2015 544 547 10.1016/j.proeng.2015.08.710 Fachbereich Medizintechnik und Technomathematik OPUS4-7589 Konferenzveröffentlichung Breuer, Lars, L.Breuer@fh-aachen.de; Raue, Markus, raue@fh-aachen.de; Mang, Thomas, mang@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de; Thoelen, Ronald, ; Wagner, Torsten, torsten.wagner@fh-aachen.de Light-stimulated hydrogel actuators with incorporated graphene oxide for microfluidic applications 2015 3 12. Dresdner Sensor-Symposium 2015 206 209 10.5162/12dss2015/P5.8 Fachbereich Chemie und Biotechnologie OPUS4-7591 Wissenschaftlicher Artikel Schusser, Sebastian, schusser@fh-aachen.de; Krischer, Maximillian, ; Bäcker, Matthias, ; Poghossian, Arshak, poghossian@fh-aachen.de; Wagner, Patrick, ; Schöning, Michael Josef, schoening@fh-aachen.de Monitoring of the Enzymatically Catalyzed Degradation of Biodegradable Polymers by Means of Capacitive Field-Effect Sensors Washington, DC ACS Publications 2015 6 Analytical Chemistry 87 13 6607 6613 10.1021/acs.analchem.5b00617 Fachbereich Medizintechnik und Technomathematik OPUS4-7592 Wissenschaftlicher Artikel Miyamato, Ko-ichiro, ; Sakakita, Sakura, ; Wagner, Torsten, torsten.wagner@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de; Yoshinobu, Tatsuo, Application of chemical imaging sensor to in-situ pH imaging in the vicinity of a corroding metal surface Amsterdam Elsevier 2015 5 Electrochimica Acta 183 137 142 10.1016/j.electacta.2015.07.184 Fachbereich Medizintechnik und Technomathematik OPUS4-7594 Teil eines Buches Poghossian, Arshak, poghossian@fh-aachen.de; Schusser, Sebastian, schusser@fh-aachen.de; Bäcker, M., ; Leinhos, Marcel, leinhos@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de Real-time in-situ electrical monitoring of the degradation of biopolymers using semiconductor field-effect devices Hauppauge Nova Science Publ. 2015 18 Biodegradable biopolymers. Vol. 1 978-1-63483-632-6 135 153 Fachbereich Medizintechnik und Technomathematik OPUS4-7597 Wissenschaftlicher Artikel Murib, M. S., ; Yeap, W. S., ; Eurlings, Y., ; Grinsven, B. van, ; Boyen, H.-G., ; Conings, B., ; Michiels, L., ; Ameloot, M., ; Carleer, R., ; Warmer, J., ; Kaul, P., ; Haenen, K., ; Schöning, Michael Josef, schoening@fh-aachen.de; Ceuninck, W. de, ; Wagner, P., Heat-transfer based characterization of DNA on synthetic sapphire chips In this study, we show that synthetic sapphire (Al₂O₃), an established implant material, can also serve as a platform material for biosensors comparable to nanocrystalline diamond. Sapphire chips, beads, and powder were first modified with (3-aminopropyl) triethoxysilane (APTES), followed by succinic anhydride (SA), and finally single-stranded probe DNA was EDC coupled to the functionalized layer. The presence of the APTES-SA layer on sapphire powders was confirmed by thermogravimetric analyis and Fourier-transform infrared spectroscopy. Using planar sapphire chips as substrates and X-ray photoelectron spectroscopy (XPS) as surface-sensitive tool, the sequence of individual layers was analyzed with respect to their chemical state, enabling the quantification of areal densities of the involved molecular units. Fluorescence microscopy was used to demonstrate the hybridization of fluorescently tagged target DNA to the probe DNA, including denaturation- and re-hybridization experiments. Due to its high thermal conductivity, synthetic sapphire is especially suitable as a chip material for the heat-transfer method, which was employed to distinguish complementary- and non-complementary DNA duplexes containing single-nucleotide polymorphisms. These results indicate that it is possible to detect mutations electronically with a chemically resilient and electrically insulating chip material. Amsterdam Elsevier 2016 11 Sensors and Actuators B: Chemical 230 230 260 271 10.1016/j.snb.2016.02.027 bezahl https://doi.org/10.1016/j.snb.2016.02.027 Fachbereich Medizintechnik und Technomathematik OPUS4-7604 Wissenschaftlicher Artikel Hamad, E. M., ; Bilatto, S. E. R., ; Adly, N. Y., ; Correa, D. S., ; Wolfrum, B., ; Schöning, Michael Josef, schoening@fh-aachen.de; Offenhäusser, A., ; Yakushenko, A., Inkjet printing of UV-curable adhesive and dielectric inks for microfluidic devices Bonding of polymer-based microfluidics to polymer substrates still poses a challenge for Lab-On-a-Chip applications. Especially, when sensing elements are incorporated, patterned deposition of adhesives with curing at ambient conditions is required. Here, we demonstrate a fabrication method for fully printed microfluidic systems with sensing elements using inkjet and stereolithographic 3D-printing. Cambridge Royal Society of Chemistry 2016 4 Lab on a Chip 16 1 70 74 10.1039/C5LC01195G campus https://doi.org/10.1039/C5LC01195G Fachbereich Medizintechnik und Technomathematik OPUS4-7610 Konferenzveröffentlichung Poghossian, Arshak, poghossian@fh-aachen.de; Bronder, Thomas, bronder@fh-aachen.de; Wu, Chunsheng, C.Wu@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de Label-free sensing of biomolecules by their intrinsic molecular charge using field-effect devices 2015 2 Semiconductor Micro- and Nanoelectonics : Proceedings of the tenth international conference, Yerevan, Armenia, September 11-13 978-5-8084-1991-9 ICSMN-2015 61 63 weltweit https://www.researchgate.net/publication/282976536_LABEL-FREE_SENSING_OF_BIOMOLECULES_BY_THEIR_INTRINSIC_MOLECULAR_CHARGE_USING_FIELD-EFFECT_DEVICES Fachbereich Medizintechnik und Technomathematik OPUS4-7724 Wissenschaftlicher Artikel Miyamoto, Ko-ichiro, ; Yu, Bing, ; Isoda, Hiroko, ; Wagner, Torsten, torsten.wagner@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de; Yoshinobu, Tatsuo, Visualization of the recovery process of defects in a cultured cell layer by chemical imaging sensor The chemical imaging sensor is a field-effect sensor which is able to visualize both the distribution of ions (in LAPS mode) and the distribution of impedance (in SPIM mode) in the sample. In this study, a novel cell assay is proposed, in which the chemical imaging sensor operated in SPIM mode is applied to monitor the recovery of defects in a cell layer brought into proximity of the sensing surface. A reduced impedance at a defect formed artificially in a cell layer was successfully visualized in a photocurrent image. The cell layer was cultured over two weeks, during which the temporal change of the photocurrent distribution corresponding to the recovery of the defect was observed. Amsterdam Elsevier 2016 4 Sensors and Actuators B: Chemical 236 965 969 10.1016/j.snb.2016.04.018 bezahl https://doi.org/10.1016/j.snb.2016.04.018 Fachbereich Medizintechnik und Technomathematik OPUS4-7729 Wissenschaftlicher Artikel Dantism, Shahriar, Dantism@fh-aachen.de; Takenaga, Shoko, ; Wagner, Patrick, ; Wagner, Torsten, torsten.wagner@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de Determination of the extracellular acidification of Escherichia coli K12 with a multi-​chamber-​based LAPS system On-line monitoring of the metabolic activity of microorganisms involved in intermediate stages of biogas production plays an important role to avoid undesirable "down times" during the biogas production. In order to control this process, an on-chip differential measuring system based on the light-addressable potentiometric sensor (LAPS) principle combined with a 3D-printed multi-chamber structure has been realized. As a test microorganism, Escherichia coli K12 (E. coli K12) were used for cell-based measurements. Multi-chamber structures were developed to determine the metabolic activity of E. coli K12 in suspension for a different number of cells, responding to the addition of a constant or variable amount of glucose concentrations, enabling differential and simultaneous measurements. Weinheim Wiley-VCH 2016 6 Physica status solidi (a) 213 6 1479 1485 10.1002/pssa.201533043 campus https://doi.org/10.1002/pssa.201533043 Fachbereich Medizintechnik und Technomathematik OPUS4-7731 Wissenschaftlicher Artikel Breuer, Lars, L.Breuer@fh-aachen.de; Raue, Markus, raue@fh-aachen.de; Strobel, M., ; Mang, Thomas, mang@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de; Thoelen, R., ; Wagner, Torsten, torsten.wagner@fh-aachen.de Hydrogels with incorporated graphene oxide as light-addressable actuator materials for cell culture environments in lab-on-chip systems Abstractauthoren Graphene oxide (GO) nanoparticles were incorporated in temperature-sensitive Poly(N-isopropylacrylamide) (PNIPAAm) hydrogels. The nanoparticles increase the light absorption and convert light energy into heat efficiently. Thus, the hydrogels with GO can be stimulated spatially resolved by illumination as it was demonstrated by IR thermography. The temporal progression of the temperature maximum was detected for different concentrations of GO within the polymer network. Furthermore, the compatibility of PNIPAAm hydrogels with GO and cell cultures was investigated. For this purpose, culture medium was incubated with hydrogels containing GO and the viability and morphology of chinese hamster ovary (CHO) cells was examined after several days of culturing in presence of this medium. Weinheim Wiley-VCH 2016 5 Physica status solidi (a) 213 6 1520 1525 10.1002/pssa.201533056 campus https://doi.org/10.1002/pssa.201533056 Fachbereich Chemie und Biotechnologie OPUS4-7692 Wissenschaftlicher Artikel Wu, Chunsheng, C.Wu@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de; Bronder, Thomas, bronder@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de Sensing of double-stranded DNA molecules by their intrinsic molecular charge using the light-addressable potentiometric sensor A multi-spot light-addressable potentiometric sensor (LAPS), which belongs to the family of semiconductor field-effect devices, was applied for label-free detection of double-stranded deoxyribonucleic acid (dsDNA) molecules by their intrinsic molecular charge. To reduce the distance between the DNA charge and sensor surface and thus, to enhance the electrostatic coupling between the dsDNA molecules and the LAPS, the negatively charged dsDNA molecules were electrostatically adsorbed onto the gate surface of the LAPS covered with a positively charged weak polyelectrolyte layer of PAH (poly(allylamine hydrochloride)). The surface potential changes in each spot of the LAPS, induced by the layer-by-layer adsorption of a PAH/dsDNA bilayer, were recorded by means of photocurrent-voltage and constant-photocurrent measurements. In addition, the surface morphology of the gate surface before and after consecutive electrostatic adsorption of PAH and dsDNA layers was studied by atomic force microscopy measurements. Moreover, fluorescence microscopy was used to verify the successful adsorption of dsDNA molecules onto the PAH-modified LAPS surface. A high sensor signal of 25 mV was registered after adsorption of 10 nM dsDNA molecules. The lower detection limit is down to 0.1 nM dsDNA. The obtained results demonstrate that the PAH-modified LAPS device provides a convenient and rapid platform for the direct label-free electrical detection of in-solution hybridized dsDNA molecules. Amsterdam Elsevier 2016 6 Sensors and Actuators B: Chemical 229 506 512 10.1016/j.snb.2016.02.004 bezahl https://doi.org/10.1016/j.snb.2016.02.004 Fachbereich Medizintechnik und Technomathematik OPUS4-7821 Wissenschaftlicher Artikel Bäcker, Matthias, ; Koch, Claudia, ; Eiben, Sabine, ; Geiger, Fania, ; Eber, Fabian, ; Gliemann, Hartmut, ; Poghossian, Arshak, poghossian@fh-aachen.de; Wege, Christina, ; Schöning, Michael Josef, schoening@fh-aachen.de Tobacco mosaic virus as enzyme nanocarrier for electrochemical biosensors Amsterdam Elsevier 2017 6 Sensors and Actuators B: Chemical 238 716 722 10.1016/j.snb.2016.07.096 Fachbereich Medizintechnik und Technomathematik OPUS4-7799 Wissenschaftlicher Artikel Miyamoto, Ko-Ichiro, ; Sato, Takuya, ; Abe, Minami, ; Wagner, Torsten, torsten.wagner@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de; Yoshinobu, Tatsuo, Light-addressable potentiometric sensor as a sensing element in plug-based microfluidic devices A plug-based microfluidic system based on the principle of the light-addressable potentiometric sensor (LAPS) is proposed. The LAPS is a semiconductor-based chemical sensor, which has a free addressability of the measurement point on the sensing surface. By combining a microfluidic device and LAPS, ion sensing can be performed anywhere inside the microfluidic channel. In this study, the sample solution to be measured was introduced into the channel in a form of a plug with a volume in the range of microliters. Taking advantage of the light-addressability, the position of the plug could be monitored and pneumatically controlled. With the developed system, the pH value of a plug with a volume down to 400 nL could be measured. As an example of plug-based operation, two plugs were merged in the channel, and the pH change was detected by differential measurement. Basel MDPI 2016 Micromachines 7 This article belongs to the Special Issue "Micro/Nano Devices for Chemical Analysis" 7 111 10.3390/mi7070111 weltweit https://doi.org/10.3390/mi7070111 Fachbereich Medizintechnik und Technomathematik OPUS4-7801 Wissenschaftlicher Artikel Doll, Theodor, ; Wagner, Torsten, torsten.wagner@fh-aachen.de; Wagner, Patrick, ; Schöning, Michael Josef, schoening@fh-aachen.de Engineering of functional interfaces / Theodor Doll ; Torsten Wagner ; Patrick Wagner ; Michael J. Schöning (eds.) Weinheim Wiley-VCH 2016 1 Physica status solidi (a) 213 6 1393 1394 10.1002/pssa.201670641 campus https://doi.org/10.1002/pssa.201670641 Fachbereich Medizintechnik und Technomathematik OPUS4-7940 Wissenschaftlicher Artikel Poghossian, Arshak, poghossian@fh-aachen.de; Werner, Frederik, f.werner@fh-aachen.de; Buniatyan, V. V., ; Wagner, Torsten, torsten.wagner@fh-aachen.de; Miamoto, K., ; Yoshinobu, T., ; Schöning, Michael Josef, schoening@fh-aachen.de Towards addressability of light-addressable potentiometric sensors: Shunting effect of non-illuminated region and cross-talk Amsterdam Elsevier 2017 8 Sensor and Actuators B: Chemical 244 1071 1079 10.1016/j.snb.2017.01.047 Fachbereich Medizintechnik und Technomathematik OPUS4-7932 Konferenzveröffentlichung Bäcker, Matthias, ; Koch, C., ; Geiger, F., ; Eber, F., ; Gliemann, H., ; Poghossian, Arshak, poghossian@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de A New Class of Biosensors Based on Tobacco Mosaic Virus and Coat Proteins as Enzyme Nanocarrier 2016 3 Procedia Engineering Vol. 168 Proceedings of the 30th anniversary Eurosensors Conference - Eurosensors 2016, 4-7. Sepember 2016, Budapest, Hungary 618 621 10.1016/j.proeng.2016.11.228 Fachbereich Medizintechnik und Technomathematik OPUS4-7934 Wissenschaftlicher Artikel Katz, Evgeny, ; Poghossian, Arshak, poghossian@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de Enzyme-based logic gates and circuits - analytical applications and interfacing with electronics Berlin Springer 2017 13 Analytical and Bioanalytical Chemistry 409 1 81 94 10.1007/s00216-016-0079-7 Fachbereich Medizintechnik und Technomathematik OPUS4-7935 Konferenzveröffentlichung Poghossian, Arshak, poghossian@fh-aachen.de; Bronder, Thomas, bronder@fh-aachen.de; Scheja, S., ; Wu, Chunsheng, C.Wu@fh-aachen.de; Metzger-Boddien, C., ; Keusgen, M., ; Schöning, Michael Josef, schoening@fh-aachen.de Label-free Electrostatic Detection of DNA Amplification by PCR Using Capacitive Field-effect Devices A capacitive field-effect EIS (electrolyte-insulator-semiconductor) sensor modified with a positively charged weak polyelectrolyte of poly(allylamine hydrochloride) (PAH)/single-stranded probe DNA (ssDNA) bilayer has been used for a label-free electrostatic detection of pathogen-specific DNA amplification via polymerase chain reaction (PCR). The sensor is able to distinguish between positive and negative PCR solutions, to detect the existence of target DNA amplicons in PCR samples and thus, can be used as tool for a quick verification of DNA amplification and the successful PCR process. Amsterdam Elsevier 2016 3 Procedia Engineering Vol. 168 Proceedings of the 30th anniversary Eurosensors Conference - Eurosensors 2016, 4-7. Sepember 2016, Budapest, Hungary 514 517 10.1016/j.proeng.2016.11.512 weltweit https://doi.org/10.1016/j.proeng.2016.11.512 Fachbereich Medizintechnik und Technomathematik OPUS4-7965 Wissenschaftlicher Artikel Honarvarfard, Elham, ; Gamella, Maria, ; Channaveerappa, Devika, ; Darie, Costel C., ; Poghossian, Arshak, poghossian@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de; Katz, Evgeny, Electrochemically Stimulated Insulin Release from a Modified Graphene-functionalized Carbon Fiber Electrode Weinheim Wiley-VCH 2017 11 Electroanalysis 29 Early view 1 12 10.1002/elan.201700095 Fachbereich Medizintechnik und Technomathematik OPUS4-8062 Wissenschaftlicher Artikel Gamella, Maria, ; Zakharchenko, Andrey, ; Guz, Nataliia, ; Masi, Madeline, ; Minko, Sergiy, ; Kolpashchikov, Dmitry M., ; Iken, Heiko, iken@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de; Katz, Evgeny, DNA computing system activated by electrochemically triggered DNA realease from a polymer-brush-modified electrode array Weinheim Wiley-VCH 2017 10 Electroanalysis 29 2 398 408 10.1002/elan.201600389 Fachbereich Medizintechnik und Technomathematik OPUS4-8063 Wissenschaftlicher Artikel Sousa, Marcos A. M., ; Siqueira, Jose R. Jr., ; Vercik, Andres, ; Schöning, Michael Josef, schoening@fh-aachen.de; Oliveira, Osvaldo N. Jr., Determining the optimized layer-by-layer film architecture with dendrimer/carbon nanotubes for field-effect sensors New York IEEE 2017 5 IEEE Sensors Journal 17 6 1735 1740 10.1109/JSEN.2017.2653238 Fachbereich Medizintechnik und Technomathematik OPUS4-8064 Wissenschaftlicher Artikel Yoshinobu, Tatsuo, ; Miyamoto, Ko-ichiro, ; Werner, Frederik, f.werner@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de; Wagner, Torsten, torsten.wagner@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de Light-addressable potentiometric sensors for quantitative spatial imaging of chemical species 2017 21 Annual Review of Analytical Chemistry 10 225 246 10.1146/annurev-anchem-061516-045158 Fachbereich Medizintechnik und Technomathematik OPUS4-8131 Konferenzveröffentlichung Miyamoto, Ko-ichiro, ; Suto, Takeyuki, ; Werner, Frederik, f.werner@fh-aachen.de; Wagner, Torsten, torsten.wagner@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de; Yoshinobu, Tatsuo, Restraining the Diffusion of Photocarriers to Improve the Spatial Resolution of the Chemical Imaging Sensor 2017 4 Seiten MDPI Proceedings 1 Eurosensors 2017 Conference, Paris, France, 3-6 September 2017 4 10.3390/proceedings1040477 Fachbereich Medizintechnik und Technomathematik OPUS4-8136 Wissenschaftlicher Artikel Muschallik, Lukas, muschallik@fh-aachen.de; Molinnus, Denise, molinnus@fh-aachen.de; Bongaerts, Johannes, bongaerts@fh-aachen.de; Pohl, Martina, ; Wagner, Torsten, torsten.wagner@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de; Siegert, Petra, siegert@fh-aachen.de; Selmer, Thorsten, selmer@fh-aachen.de (R,R)-Butane-2,3-diol Dehydrogenase from Bacillus clausii DSM 8716T: Cloning and Expression of the bdhA-Gene, and Initial Characterization of Enzyme Amsterdam Elsevier 2017 Journal of Biotechnology In Press, Accepted Manuscript 10.1016/j.jbiotec.2017.07.020 campus https://doi.org/10.1016/j.jbiotec.2017.07.020 Fachbereich Chemie und Biotechnologie OPUS4-8137 Wissenschaftlicher Artikel Figueroa-Miranda, Gabriela, ; Feng, Lingyan, ; Shiu, Simon Chi-Chin, ; Dirkzwager, Roderick Marshall, ; Cheung, Yee-Wai, ; Tanner, Julian Alexander, ; Schöning, Michael Josef, schoening@fh-aachen.de; Offenhäusser, Andreas, ; Mayer, Dirk, Aptamer-based electrochemical biosensor for highly sensitive and selective malaria detection with adjustable dynamic response range and reusability Malaria infection remains a significant risk for much of the population of tropical and subtropical areas, particularly in developing countries. Therefore, it is of high importance to develop sensitive, accurate and inexpensive malaria diagnosis tests. Here, we present a novel aptamer-based electrochemical biosensor (aptasensor) for malaria detection by impedance spectroscopy, through the specific recognition between a highly discriminatory DNA aptamer and its target Plasmodium falciparum lactate dehydrogenase (PfLDH). Interestingly, due to the isoelectric point (pI) of PfLDH, the aptasensor response showed an adjustable detection range based on the different protein net-charge at variable pH environments. The specific aptamer recognition allows sensitive protein detection with an expanded detection range and a low detection limit, as well as a high specificity for PfLDH compared to analogous proteins. The specific feasibility of the aptasensor is further demonstrated by detection of the target PfLDH in human serum. Furthermore, the aptasensor can be easily regenerated and thus applied for multiple usages. The robustness, sensitivity, and reusability of the presented aptasensor make it a promising candidate for point-of-care diagnostic systems. Amsterdam Elsevier 2018 8 Sensor and Actuators B: Chemical 255 P1 235 243 10.1016/j.snb.2017.07.117 bezahl https://doi.org/10.1016/j.snb.2017.07.117 Fachbereich Medizintechnik und Technomathematik OPUS4-8138 Wissenschaftlicher Artikel Morais, Paulo V., ; Gomes, Vanderley F., Jr., ; Silva, Anielle C. A., ; Dantas, Noelio O., ; Schöning, Michael Josef, schoening@fh-aachen.de; Siqueira, José R., Jr., Nanofilm of ZnO nanocrystals/carbon nanotubes as biocompatible layer for enzymatic biosensors in capacitive field-effect devices Berlin Springer 2017 11 Journal of Materials Science 52 20 12314 12325 10.1007/s10853-017-1369-y Fachbereich Medizintechnik und Technomathematik OPUS4-8139 Wissenschaftlicher Artikel Dantism, Shahriar, Dantism@fh-aachen.de; Takenaga, Shoko, ; Wagner, Torsten, torsten.wagner@fh-aachen.de; Wagner, Patrick, ; Schöning, Michael Josef, schoening@fh-aachen.de Differential imaging of the metabolism of bacteria and eukaryotic cells based on light-addressable potentiometric sensors Amsterdam Elsevier 2017 7 Electrochimica Acta 246 234 241 10.1016/j.electacta.2017.05.196 Fachbereich Medizintechnik und Technomathematik OPUS4-8140 Wissenschaftlicher Artikel Jildeh, Zaid B., ; Kirchner, Patrick, kirchner@fh-aachen.de; Oberländer, Jan, oberlaender@fh-aachen.de; Kremers, Alexander, ; Wagner, Torsten, torsten.wagner@fh-aachen.de; Wagner, Patrick H., ; Schöning, Michael Josef, schoening@fh-aachen.de FEM-based modeling of a calorimetric gas sensor for hydrogen peroxide monitoring Weinheim Wiley-VCH 2017 physica status solidi a : applications and materials sciences Early View 10.1002/pssa.201600912 Fachbereich Medizintechnik und Technomathematik OPUS4-8130 Konferenzveröffentlichung Jablonski, Melanie, ; Koch, Claudia, ; Bronder, Thomas, bronder@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de; Wege, Christina, ; Schöning, Michael Josef, schoening@fh-aachen.de Field-Effect Biosensors Modified with Tobacco Mosaic Virus Nanotubes as Enzyme Nanocarrier 2017 4 MDPI Proceeding 1 Eurosensors 2017 Conference, Paris, France, 3-6 September 2017 4 10.3390/proceedings1040505 Fachbereich Medizintechnik und Technomathematik OPUS4-8144 Teil eines Buches Poghossian, Arshak, poghossian@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de Nanomaterial-Modified Capacitive Field-Effect Biosensors The coupling of charged molecules, nanoparticles, and more generally, inorganic/organic nanohybrids with semiconductor field-effect devices based on an electrolyte-insulator-semiconductor (EIS) system represents a very promising strategy for the active tuning of electrochemical properties of these devices and, thus, opening new opportunities for label-free biosensing by the intrinsic charge of molecules. The simplest field-effect sensor is a capacitive EIS sensor, which represents a (bio-)chemically sensitive capacitor. In this chapter, selected examples of recent developments in the field of label-free biosensing using nanomaterial-modified capacitive EIS sensors are summarized. In the first part, we present applications of EIS sensors modified with negatively charged gold nanoparticles for the label-free electrostatic detection of positively charged small proteins and macromolecules, for monitoring the layer-by-layer formation of oppositely charged polyelectrolyte (PE) multilayers as well as for the development of an enzyme-based biomolecular logic gate. In the second part, examples of a label-free detection by means of EIS sensors modified with a positively charged weak PE layer are demonstrated. These include electrical detection of on-chip and in-solution hybridized DNA (deoxyribonucleic acid) as well as an EIS sensor with pH-responsive weak PE/enzyme multilayers for enhanced field-effect biosensing. Berlin, Heidelberg Springer 2017 24 Springer Series on Chemical Sensors and Biosensors (Methods and Applications) 1 25 10.1007/5346_2017_2 campus https://doi.org/10.1007/5346_2017_2 Fachbereich Medizintechnik und Technomathematik OPUS4-8146 Wissenschaftlicher Artikel Miyamoto, Ko-ichiro, ; Hayashi, Kosuke, ; Sakamoto, Azuma, ; Werner, Frederik, f.werner@fh-aachen.de; Wagner, Torsten, torsten.wagner@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de; Yoshinobu, Tatsuo, A high-Q resonance-mode measurement of EIS capacitive sensor by elimination of series resistance Amsterdam Elsevier 2017 4 Sensor and Actuators B: Chemical 248 1006 1010 10.1016/j.snb.2017.03.002 bezahl Fachbereich Medizintechnik und Technomathematik OPUS4-8147 Wissenschaftlicher Artikel Werner, Frederik, f.werner@fh-aachen.de; Miyamoto, Ko-ichiro, ; Wagner, Torsten, torsten.wagner@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de; Yoshinobu, Tatsuo, Lateral resolution enhancement of pulse-driven light-addressable potentiometric sensor Amsterdam Elsevier 2017 4 Sensor and Actuators B: Chemical 248 961 965 10.1016/j.snb.2017.02.057 Fachbereich Medizintechnik und Technomathematik OPUS4-8148 Wissenschaftlicher Artikel Scholl, Fabio, ; Morais, Paulo, ; Gabriel, Rayla, ; Schöning, Michael Josef, schoening@fh-aachen.de; Siqueira, Jose Roberto, Jr., ; Caseli, Luciano, Carbon nanotubes arranged as smart interfaces in lipid Langmuir-Blodgett films enhancing the enzymatic properties of penicillinase for biosensing applications 2017 Applied Materials & Interfaces Just Accepted Mauscript 10.1021/acsami.7b08095 Fachbereich Medizintechnik und Technomathematik OPUS4-8155 Wissenschaftlicher Artikel Honarvarfard, Elham, ; Gamella, Maria, ; Poghossian, Arshak, poghossian@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de; Katz, Evgeny, An enzyme-based reversible Controlled NOT (CNOT) logic gate operating on a semiconductor transducer Amsterdam Elsevier 2017 4 Applied Materials Today 9 266 270 10.1016/j.apmt.2017.08.003 Fachbereich Medizintechnik und Technomathematik OPUS4-8157 Wissenschaftlicher Artikel Röhlen, Desiree, roehlen@fh-aachen.de; Pilas, Johanna, pilas@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de; Selmer, Thorsten, selmer@fh-aachen.de Development of an Amperometric Biosensor Platform for the Combined Determination of l-Malic, Fumaric, and l-Aspartic Acid Berlin Springer 2017 15 Applied Biochemistry and Biotechnology 1 16 10.1007/s12010-017-2578-1 Fachbereich Chemie und Biotechnologie OPUS4-8162 Konferenzveröffentlichung Breuer, Lars, L.Breuer@fh-aachen.de; Guthmann, Eric, ; Schöning, Michael Josef, schoening@fh-aachen.de; Thoelen, Ronald, ; Wagner, Torsten, torsten.wagner@fh-aachen.de Light-Stimulated Hydrogels with Incorporated Graphene Oxide as Actuator Material for Flow Control in Microfluidic Applications 2017 3 Proceedings Eurosensors 2017 Conference, Paris, France, 3–6 September 2017 1 4 10.3390/proceedings1040524 Fachbereich Medizintechnik und Technomathematik OPUS4-8198 Wissenschaftlicher Artikel Breuer, Lars, L.Breuer@fh-aachen.de; Mang, Thomas, mang@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de; Thoelen, Ronald, ; Wagner, Torsten, torsten.wagner@fh-aachen.de Investigation of the spatial resolution of a laser-based stimulation process for light-addressable hydrogels with incorporated graphene oxide by means of IR thermography Amsterdam Elsevier 2017 6 Sensors and Actuators A: Physical 268 126 132 10.1016/j.sna.2017.11.031 http://doi.org/10.1016/j.sna.2017.11.031 Fachbereich Chemie und Biotechnologie OPUS4-8381 Wissenschaftlicher Artikel Koch, Claudia, ; Poghossian, Arshak, poghossian@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de; Wege, Christian, Penicillin Detection by Tobacco Mosaic Virus-Assisted Colorimetric Biosensors The presentation of enzymes on viral scaffolds has beneficial effects such as an increased enzyme loading and a prolonged reusability in comparison to conventional immobilization platforms. Here, we used modified tobacco mosaic virus (TMV) nanorods as enzyme carriers in penicillin G detection for the first time. Penicillinase enzymes were conjugated with streptavidin and coupled to TMV rods by use of a bifunctional biotin-linker. Penicillinase-decorated TMV particles were characterized extensively in halochromic dye-based biosensing. Acidometric analyte detection was performed with bromcresol purple as pH indicator and spectrophotometry. The TMV-assisted sensors exhibited increased enzyme loading and strongly improved reusability, and higher analysis rates compared to layouts without viral adapters. They extended the half-life of the sensors from 4 - 6 days to 5 weeks and thus allowed an at least 8-fold longer use of the sensors. Using a commercial budget-priced penicillinase preparation, a detection limit of 100 µM penicillin was obtained. Initial experiments also indicate that the system may be transferred to label-free detection layouts. Sydney Ivyspring 2018 12 Nanotheranostics 2 2 184 196 10.7150/ntno.22114 weltweit http://doi.org/10.7150/ntno.22114 Fachbereich Medizintechnik und Technomathematik OPUS4-8421 Wissenschaftlicher Artikel Pilas, Johanna, pilas@fh-aachen.de; Yazici, Y., ; Selmer, Thorsten, selmer@fh-aachen.de; Keusgen, M., ; Schöning, Michael Josef, schoening@fh-aachen.de Application of a portable multi-analyte biosensor for organic acid determination in silage Multi-analyte biosensors may offer the opportunity to perform cost-effective and rapid analysis with reduced sample volume, as compared to electrochemical biosensing of each analyte individually. This work describes the development of an enzyme-based biosensor system for multi-parametric determination of four different organic acids. The biosensor array comprises five working electrodes for simultaneous sensing of ethanol, formate, d-lactate, and l-lactate, and an integrated counter electrode. Storage stability of the biosensor was evaluated under different conditions (stored at +4 °C in buffer solution and dry at −21 °C, +4 °C, and room temperature) over a period of 140 days. After repeated and regular application, the individual sensing electrodes exhibited the best stability when stored at −21 °C. Furthermore, measurements in silage samples (maize and sugarcane silage) were conducted with the portable biosensor system. Comparison with a conventional photometric technique demonstrated successful employment for rapid monitoring of complex media. Basel MDPI 2018 12 Seiten Sensors 18 Article number 1470 5 10.3390/s18051470 weltweit https://doi.org/10.3390/s18051470 Fachbereich Chemie und Biotechnologie OPUS4-8423 Wissenschaftlicher Artikel Dantism, Shahriar, Dantism@fh-aachen.de; Röhlen, Desiree, roehlen@fh-aachen.de; Wagner, Torsten, torsten.wagner@fh-aachen.de; Wagner, Patrick, ; Schöning, Michael Josef, schoening@fh-aachen.de Optimization of Cell-Based Multi-Chamber LAPS Measurements Utilizing FPGA-Controlled Laser-Diode Modules A light-addressable potentiometric sensor (LAPS) is a field-effect-based potentiometric device, which detects concentration changes of an analyte solution on the sensor surface in a spatially resolved way. It uses a light source to generate electron-hole pairs inside the semiconductor, which are separated in the depletion region due to an applied bias voltage across the sensor structure and hence, a surface-potential-dependent photocurrent can be read out. However, depending on the beam angle of the light source, scattering effects can occur, which influence the recorded signal in LAPS-based differential measurements. To solve this problem, a novel illumination unit based on a field programmable gate array (FPGA) consisting of 16 small-sized tunable infrared laser-diode modules (LDMs) is developed. Due to the improved focus of the LDMs with a beam angle of only 2 mrad, undesirable scattering effects are minimized. Escherichia coli (E. coli) K12 bacteria are used as a test microorganism to study the extracellular acidification on the sensor surface. Furthermore, a salt bridge chamber is built up and integrated with the LAPS system enabling multi-chamber differential measurements with a single Ag/AgCl reference electrode. Weinheim Wiley-VCH 2018 physica status solidi a : applications and materials sciences 215 15 Article number 1800058 10.1002/pssa.201800058 campus https://doi.org/10.1002/pssa.201800058 Fachbereich Medizintechnik und Technomathematik OPUS4-8428 Wissenschaftlicher Artikel Welden, Rene, welden@fh-aachen.de; Scheja, Sabrina, ; Schöning, Michael Josef, schoening@fh-aachen.de; Wagner, Patrick, ; Wagner, Torsten, torsten.wagner@fh-aachen.de Electrochemical Evaluation of Light-Addressable Electrodes Based on TiO2 for the Integration in Lab-on-Chip Systems In lab-on-chip systems, electrodes are important for the manipulation (e.g., cell stimulation, electrolysis) within such systems. An alternative to commonly used electrode structures can be a light-addressable electrode. Here, due to the photoelectric effect, the conducting area can be adjusted by modification of the illumination area which enables a flexible control of the electrode. In this work, titanium dioxide based light-addressable electrodes are fabricated by a sol-gel technique and a spin-coating process, to deposit a thin film on a fluorine-doped tin oxide glass. To characterize the fabricated electrodes, the thickness, and morphological structure are measured by a profilometer and a scanning electron microscope. For the electrochemical behavior, the dark current and the photocurrent are determined for various film thicknesses. For the spatial resolution behavior, the dependency of the photocurrent while changing the area of the illuminated area is studied. Furthermore, the addressing of single fluid compartments in a three-chamber system, which is added to the electrode, is demonstrated. Weinheim Wiley-VCH 2018 physica status solidi a : applications and materials sciences 215 15 Article number 1800150 10.1002/pssa.201800150 campus https://doi.org/10.1002/pssa.201800150 Fachbereich Medizintechnik und Technomathematik OPUS4-8429 Teil eines Buches Koch, Claudia, ; Poghossian, Arshak, poghossian@fh-aachen.de; Wege, Christina, ; Schöning, Michael Josef, schoening@fh-aachen.de Wege, Christina TMV-Based Adapter Templates for Enhanced Enzyme Loading in Biosensor Applications Nanotubular tobacco mosaic virus (TMV) particles and RNA-free lower-order coat protein (CP) aggregates have been employed as enzyme carriers in different diagnostic layouts and compared for their influence on biosensor performance. In the following, we describe a label-free electrochemical biosensor for improved glucose detection by use of TMV adapters and the enzyme glucose oxidase (GOD). A specific and efficient immobilization of streptavidin-conjugated GOD ([SA]-GOD) complexes on biotinylated TMV nanotubes or CP aggregates was achieved via bioaffinity binding. Glucose sensors with adsorptively immobilized [SA]-GOD, and with [SA]-GOD cross-linked with glutardialdehyde, respectively, were tested in parallel on the same sensor chip. Comparison of these sensors revealed that TMV adapters enhanced the amperometric glucose detection remarkably, conveying highest sensitivity, an extended linear detection range and fastest response times. These results underline a great potential of an integration of virus/biomolecule hybrids with electronic transducers for applications in biosensorics and biochips. Here, we describe the fabrication and use of amperometric sensor chips combining an array of circular Pt electrodes, their loading with GOD-modified TMV nanotubes (and other GOD immobilization methods), and the subsequent investigations of the sensor performance. New York, NY Humana Press 2018 15 Virus-Derived Nanoparticles for Advanced Technologies 978-1-4939-7808-3 Methods in Molecular Biology, vol 1776 553 568 10.1007/978-1-4939-7808-3 bezahl https://doi.org/10.1007/978-1-4939-7808-3 Fachbereich Medizintechnik und Technomathematik OPUS4-8406 Wissenschaftlicher Artikel Vahidpour, Farnoosh, vahidpour@fh-aachen.de; Oberländer, Jan, oberlaender@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de Flexible Calorimetric Gas Sensors for Detection of a Broad Concentration Range of Gaseous Hydrogen Peroxide: A Step Forward to Online Monitoring of Food-Package Sterilization Processes In this study, flexible calorimetric gas sensors are developed for specificdetection of gaseous hydrogen peroxide (H₂O₂) over a wide concentrationrange, which is used in sterilization processes for aseptic packaging industry.The flexibility of these sensors is an advantage for identifying the chemical components of the sterilant on the corners of the food boxes, so-called "coldspots", as critical locations in aseptic packaging, which are of great importance. These sensors are fabricated on flexible polyimide films by means of thin-film technique. Thin layers of titanium and platinum have been deposited on polyimide to define the conductive structures of the sensors. To detect the high-temperature evaporated H₂O₂, a differential temperature set-up is proposed. The sensors are evaluated in a laboratory-scaled sterilizationsystem to simulate the sterilization process. The concentration range of the evaporated H₂O₂ from 0 to 7.7% v/v was defined and the sensors have successfully detected high as well as low H₂O₂ concentrations with a sensitivity of 5.04 °C/% v/v. The characterizations of the sensors confirm their precise fabrication, high sensitivity and the novelty of low H₂O₂ concentration detections for future inline monitoring of food-package sterilization. Weinheim Wiley-VCH 2018 7 Seiten Phys. Status Solidi A 215 15 Article number 1800044 10.1002/pssa.201800044 bezahl https://onlinelibrary.wiley.com/doi/abs/10.1002/pssa.201800044 Fachbereich Medizintechnik und Technomathematik OPUS4-8373 Wissenschaftlicher Artikel Jildeh, Zaid B., ; Oberländer, Jan, oberlaender@fh-aachen.de; Kirchner, Patrick, kirchner@fh-aachen.de; Wagner, Patrick H., ; Schöning, Michael Josef, schoening@fh-aachen.de Thermocatalytic Behavior of Manganese (IV) Oxide as Nanoporous Material on the Dissociation of a Gas Mixture Containing Hydrogen Peroxide In this article, we present an overview on the thermocatalytic reaction of hydrogen peroxide (H₂O₂) gas on a manganese (IV) oxide (MnO₂) catalytic structure. The principle of operation and manufacturing techniques are introduced for a calorimetric H₂O₂ gas sensor based on porous MnO₂. Results from surface analyses by X-ray photoelectron spectroscopy (XPS) and scanning electron microscopy (SEM) of the catalytic material provide indication of the H₂O₂ dissociation reaction schemes. The correlation between theory and the experiments is documented in numerical models of the catalytic reaction. The aim of the numerical models is to provide further information on the reaction kinetics and performance enhancement of the porous MnO₂ catalyst. Basel MDPI 2018 Nanomaterials 8 4 262 10.3390/nano8040262 weltweit https://doi.org/10.3390/nano8040262 Fachbereich Medizintechnik und Technomathematik OPUS4-8374 Wissenschaftlicher Artikel Bäcker, M., ; Rakowski, D., ; Krappen, E., ; Schöning, Michael Josef, schoening@fh-aachen.de Reinigungsprozesse in der Lebensmittelindustrie. Entwicklung eines Demonstrators zur Überwachung Weinheim Wiley-VCH 2017 2 GIT Labor-Fachzeitschrift 61 8 26 28 Fachbereich Medizintechnik und Technomathematik OPUS4-10715 Bericht Siegert, Petra, siegert@fh-aachen.de; Bongaerts, Johannes, bongaerts@fh-aachen.de; Wagner, Torsten, torsten.wagner@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de; Selmer, Thorsten, selmer@fh-aachen.de Abschlussbericht zum Projekt zur Überwachung biotechnologischer Prozesse mittels Diacetyl-/Acetoin-Biosensor und Evaluierung von Acetoin-Reduktasen zur Verwendung in Biotransformationen Aachen 2022 16 Seiten Laufzeit: 01.01.2016 - 31.12.2019 (verlängert bis 31.12.2020) Förderkennzeichen: 322-8.03.04.02-FH-Struktur 2016/02 Gefördert durch: Ministerium für Innovation, Wissenschaft und Forschung des Landes Nordrhein-Westfalen Fachbereich Chemie und Biotechnologie OPUS4-10789 Wissenschaftlicher Artikel Bertz, Morten, ; Molinnus, Denise, molinnus@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de; Homma, Takayuki, Real-time monitoring of H₂O₂ sterilization on individual bacillus atrophaeus spores by optical sensing with trapping Raman spectroscopy Hydrogen peroxide (H₂O₂), a strong oxidizer, is a commonly used sterilization agent employed during aseptic food processing and medical applications. To assess the sterilization efficiency with H₂O₂, bacterial spores are common microbial systems due to their remarkable robustness against a wide variety of decontamination strategies. Despite their widespread use, there is, however, only little information about the detailed time-resolved mechanism underlying the oxidative spore death by H₂O₂. In this work, we investigate chemical and morphological changes of individual Bacillus atrophaeus spores undergoing oxidative damage using optical sensing with trapping Raman microscopy in real-time. The time-resolved experiments reveal that spore death involves two distinct phases: (i) an initial phase dominated by the fast release of dipicolinic acid (DPA), a major spore biomarker, which indicates the rupture of the spore's core; and (ii) the oxidation of the remaining spore material resulting in the subsequent fragmentation of the spores' coat. Simultaneous observation of the spore morphology by optical microscopy corroborates these mechanisms. The dependence of the onset of DPA release and the time constant of spore fragmentation on H₂O₂ shows that the formation of reactive oxygen species from H₂O₂ is the rate-limiting factor of oxidative spore death. Basel MDPI 2023 Chemosensors 8 This article belongs to the Special Issue "Biosensors and Chemical Sensors for Food and Healthcare Monitoring—Celebrating the 10th Anniversary" 11 Artikel 445 10.3390/chemosensors11080445 weltweit https://doi.org/10.3390/chemosensors11080445 INB - Institut für Nano- und Biotechnologien OPUS4-10790 Wissenschaftlicher Artikel Wendlandt, Tim, ; Koch, Claudia, ; Britz, Beate, ; Liedek, Anke, ; Schmidt, Nora, ; Werner, Stefan, ; Gleba, Yuri, ; Vahidpour, Farnoosh, vahidpour@fh-aachen.de; Welden, Melanie, m.welden@fh-aachen.de; Poghossian, Arshak, ; Schöning, Michael Josef, schoening@fh-aachen.de Facile Purification and Use of Tobamoviral Nanocarriers for Antibody-Mediated Display of a Two-Enzyme System Immunosorbent turnip vein clearing virus (TVCV) particles displaying the IgG-binding domains D and E of Staphylococcus aureus protein A (PA) on every coat protein (CP) subunit (TVCVPA) were purified from plants via optimized and new protocols. The latter used polyethylene glycol (PEG) raw precipitates, from which virions were selectively re-solubilized in reverse PEG concentration gradients. This procedure improved the integrity of both TVCVPA and the wild-type subgroup 3 tobamovirus. TVCVPA could be loaded with more than 500 IgGs per virion, which mediated the immunocapture of fluorescent dyes, GFP, and active enzymes. Bi-enzyme ensembles of cooperating glucose oxidase and horseradish peroxidase were tethered together on the TVCVPA carriers via a single antibody type, with one enzyme conjugated chemically to its Fc region, and the other one bound as a target, yielding synthetic multi-enzyme complexes. In microtiter plates, the TVCVPA-displayed sugar-sensing system possessed a considerably increased reusability upon repeated testing, compared to the IgG-bound enzyme pair in the absence of the virus. A high coverage of the viral adapters was also achieved on Ta2O5 sensor chip surfaces coated with a polyelectrolyte interlayer, as a prerequisite for durable TVCVPA-assisted electrochemical biosensing via modularly IgG-assembled sensor enzymes. Basel MDPI 2023 Viruses 9 This article belongs to the Special Issue "Tobamoviruses 2023" 15 Artikel 1951 doi.org/10.3390/v15091951 weltweit https://doi.org/10.3390/v15091951 INB - Institut für Nano- und Biotechnologien OPUS4-10742 Wissenschaftlicher Artikel Morais, Paulo V., ; Suman, Pedro H., ; Schöning, Michael Josef, schoening@fh-aachen.de; Siqueira Junior, José R., ; Orlandi, Marcelo O., Layer-by-layer film based on Sn₃O₄ nanobelts as sensing units to detect heavy metals using a capacitive field-effect sensor platform Lead and nickel, as heavy metals, are still used in industrial processes, and are classified as "environmental health hazards" due to their toxicity and polluting potential. The detection of heavy metals can prevent environmental pollution at toxic levels that are critical to human health. In this sense, the electrolyte-insulator-semiconductor (EIS) field-effect sensor is an attractive sensing platform concerning the fabrication of reusable and robust sensors to detect such substances. This study is aimed to fabricate a sensing unit on an EIS device based on Sn₃O₄ nanobelts embedded in a polyelectrolyte matrix of polyvinylpyrrolidone (PVP) and polyacrylic acid (PAA) using the layer-by-layer (LbL) technique. The EIS-Sn₃O₄ sensor exhibited enhanced electrochemical performance for detecting Pb²⁺ and Ni²⁺ ions, revealing a higher affinity for Pb²⁺ ions, with sensitivities of ca. 25.8 mV/decade and 2.4 mV/decade, respectively. Such results indicate that Sn₃O₄ nanobelts can contemplate a feasible proof-of-concept capacitive field-effect sensor for heavy metal detection, envisaging other future studies focusing on environmental monitoring. Basel MDPI 2023 10 Chemosensors 11 This article belongs to the Special Issue The Application of Electrochemical Sensors or Biosensors Based on Nanomaterials 8 1 11 10.3390/chemosensors11080436 weltweit https://doi.org/10.3390/chemosensors11080436 Fachbereich Medizintechnik und Technomathematik OPUS4-10928 Wissenschaftlicher Artikel Karschuck, Tobias, karschuck@fh-aachen.de; Schmidt, Stefan, s.schmidt@fh-aachen.de; Achtsnicht, Stefan, achtsnicht@fh-aachen.de; Poghossian, Arshak, ; Wagner, Patrick, ; Schöning, Michael Josef, schoening@fh-aachen.de Multiplexing system for automated characterization of a capacitive field-effect sensor array In comparison to single-analyte devices, multiplexed systems for a multianalyte detection offer a reduced assay time and sample volume, low cost, and high throughput. Herein, a multiplexing platform for an automated quasi-simultaneous characterization of multiple (up to 16) capacitive field-effect sensors by the capacitive-voltage (C-V) and the constant-capacitance (ConCap) mode is presented. The sensors are mounted in a newly designed multicell arrangement with one common reference electrode and are electrically connected to the impedance analyzer via the base station. A Python script for the automated characterization of the sensors executes the user-defined measurement protocol. The developed multiplexing system is tested for pH measurements and the label-free detection of ligand-stabilized, charged gold nanoparticles. Weinheim Wiley-VCH 2023 7 Seiten Physica Status Solidi A 220 Corresponding author: Michael Josef Schöning 22 10.1002/pssa.202300265 weltweit https://doi.org/10.1002/pssa.202300265 Fachbereich Medizintechnik und Technomathematik OPUS4-8343 Wissenschaftlicher Artikel Poghossian, Arshak, poghossian@fh-aachen.de; Jablonski, Melanie, m.jablonski@fh-aachen.de; Koch, Claudia, ; Bronder, Thomas, bronder@fh-aachen.de; Rolka, David, d.rolka@fh-aachen.de; Wege, Christina, ; Schöning, Michael Josef, schoening@fh-aachen.de Field-effect biosensor using virus particles as scaffolds for enzyme immobilization A field-effect biosensor employing tobacco mosaic virus (TMV) particles as scaffolds for enzyme immobilization is presented. Nanotubular TMV scaffolds allow a dense immobilization of precisely positioned enzymes with retained activity. To demonstrate feasibility of this new strategy, a penicillin sensor has been developed by coupling a penicillinase with virus particles as a model system. The developed field-effect penicillin biosensor consists of an Al-p-Si-SiO₂-Ta₂O₅-TMV structure and has been electrochemically characterized in buffer solutions containing different concentrations of penicillin G. In addition, the morphology of the biosensor surface with virus particles was characterized by scanning electron microscopy and atomic force microscopy methods. The sensors possessed a high penicillin sensitivity of ~ 92 mV/dec in a nearly-linear range from 0.1 mM to 10 mM, and a low detection limit of about 50 µM. The long-term stability of the penicillin biosensor was periodically tested over a time period of about one year without any significant loss of sensitivity. The biosensor has also been successfully applied for penicillin detection in bovine milk samples. Amsterdam Elsevier 2018 6 Biosensors and Bioelectronics 110 168 174 10.1016/j.bios.2018.03.036 bezahl http://doi.org/10.1016/j.bios.2018.03.036 Fachbereich Medizintechnik und Technomathematik OPUS4-9126 Wissenschaftlicher Artikel Dantism, Shahriar, Dantism@fh-aachen.de; Röhlen, Desiree, roehlen@fh-aachen.de; Wagner, Torsten, torsten.wagner@fh-aachen.de; Wagner, P., ; Schöning, Michael Josef, schoening@fh-aachen.de A LAPS-based differential sensor for parallelized metabolism monitoring of various bacteria Basel MDPI 2019 Sensors 19 21 Article number 4692 10.3390/s19214692 weltweit https://doi.org/10.3390/s19214692 Fachbereich Medizintechnik und Technomathematik OPUS4-9127 Wissenschaftlicher Artikel Karschuck, T. L., ; Filipov, Y., ; Bollella, P., ; Schöning, Michael Josef, schoening@fh-aachen.de; Katz, E., Not-XOR (NXOR) logic gate based on an enzyme-catalyzed reaction 2019 7 International Journal of Unconventional Computing 14 3-4 235 242 Fachbereich Medizintechnik und Technomathematik OPUS4-9435 Wissenschaftlicher Artikel Poghossian, Arshak, poghossian@fh-aachen.de; Jablonski, Melanie, m.jablonski@fh-aachen.de; Molinnus, Denise, Molinnus@fh-aachen.de; Wege, Christina, ; Schöning, Michael Josef, schoening@fh-aachen.de Field-Effect Sensors for Virus Detection: From Ebola to SARS-CoV-2 and Plant Viral Enhancers Coronavirus disease 2019 (COVID-19) is a novel human infectious disease provoked by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Currently, no specific vaccines or drugs against COVID-19 are available. Therefore, early diagnosis and treatment are essential in order to slow the virus spread and to contain the disease outbreak. Hence, new diagnostic tests and devices for virus detection in clinical samples that are faster, more accurate and reliable, easier and cost-efficient than existing ones are needed. Due to the small sizes, fast response time, label-free operation without the need for expensive and time-consuming labeling steps, the possibility of real-time and multiplexed measurements, robustness and portability (point-of-care and on-site testing), biosensors based on semiconductor field-effect devices (FEDs) are one of the most attractive platforms for an electrical detection of charged biomolecules and bioparticles by their intrinsic charge. In this review, recent advances and key developments in the field of label-free detection of viruses (including plant viruses) with various types of FEDs are presented. In recent years, however, certain plant viruses have also attracted additional interest for biosensor layouts: Their repetitive protein subunits arranged at nanometric spacing can be employed for coupling functional molecules. If used as adapters on sensor chip surfaces, they allow an efficient immobilization of analyte-specific recognition and detector elements such as antibodies and enzymes at highest surface densities. The display on plant viral bionanoparticles may also lead to long-time stabilization of sensor molecules upon repeated uses and has the potential to increase sensor performance substantially, compared to conventional layouts. This has been demonstrated in different proof-of-concept biosensor devices. Therefore, richly available plant viral particles, non-pathogenic for animals or humans, might gain novel importance if applied in receptor layers of FEDs. These perspectives are explained and discussed with regard to future detection strategies for COVID-19 and related viral diseases. Lausanne Frontiers 2020 13 Frontiers in Plant Science 11 Article 598103 1 14 10.3389/fpls.2020.598103 weltweit https://doi.org/10.3389/fpls.2020.598103 Fachbereich Medizintechnik und Technomathematik OPUS4-9385 Wissenschaftlicher Artikel Poghossian, Arshak, poghossian@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de Capacitive field-effect eis chemical sensors and biosensors: A status report Electrolyte-insulator-semiconductor (EIS) field-effect sensors belong to a new generation of electronic chips for biochemical sensing, enabling a direct electronic readout. The review gives an overview on recent advances and current trends in the research and development of chemical sensors and biosensors based on the capacitive field-effect EIS structure—the simplest field-effect device, which represents a biochemically sensitive capacitor. Fundamental concepts, physicochemical phenomena underlying the transduction mechanism and application of capacitive EIS sensors for the detection of pH, ion concentrations, and enzymatic reactions, as well as the label-free detection of charged molecules (nucleic acids, proteins, and polyelectrolytes) and nanoparticles, are presented and discussed. Basel MDPI 2020 31 Sensors 20 19 art. no. 5639 1 32 10.3390/s20195639 weltweit https://doi.org/10.3390/s20195639 Fachbereich Medizintechnik und Technomathematik OPUS4-9388 Wissenschaftlicher Artikel Molinnus, Denise, Molinnus@fh-aachen.de; Beging, Stefan, beging@fh-aachen.de; Lowis, Carsten, ; Schöning, Michael Josef, schoening@fh-aachen.de Towards a multi-enzyme capacitive field-effect biosensor by comparative study of drop-coating and nano-spotting technique Multi-enzyme immobilization onto a capacitive field-effect biosensor by nano-spotting technique is presented. The nano-spotting technique allows to immobilize different enzymes simultaneously on the sensor surface with high spatial resolution without additional photolithographical patterning. The amount of applied enzymatic cocktail on the sensor surface can be tailored. Capacitive electrolyte-insulator-semiconductor (EIS) field-effect sensors with Ta2O5 as pH-sensitive transducer layer have been chosen to immobilize the three different (pL droplets) enzymes penicillinase, urease, and glucose oxidase. Nano-spotting immobilization is compared to conventional drop-coating method by defining different geometrical layouts on the sensor surface (fully, half-, and quarter-spotted). The drop diameter is varying between 84 µm and 102 µm, depending on the number of applied drops (1 to 4) per spot. For multi-analyte detection, penicillinase and urease are simultaneously nano-spotted on the EIS sensor. Sensor characterization was performed by C/V (capacitance/voltage) and ConCap (constant capacitance) measurements. Average penicillin, glucose, and urea sensitivities for the spotted enzymes were 81.7 mV/dec, 40.5 mV/dec, and 68.9 mV/dec, respectively. Basel MDPI 2020 Sensors 20 1424-8220 Special issue: Multisensor Systems and Signal Processing in Analytical Chemistry 17 art. no. 4924 10.3390/s20174924 weltweit https://doi.org/10.3390/s20174924 OPUS4-9413 Buch (Monographie) Yoshinobu, Tatsuo, ; Schöning, Michael Josef, schoening@fh-aachen.de Yoshinobu, Tatsuo; Schöning, Michael Josef Light-addressing and chemical imaging technologies for electrochemical sensing Basel MDPI 2020 122 Pages 978-3-03943-029-1 This book is a printed edition of the Special Issue Light-Addressing and Chemical Imaging Technologies for Electrochemical Sensing that was published in Sensors 10.3390/books978-3-03943-029-1 weltweit https://doi.org/10.3390/books978-3-03943-029-1 Fachbereich Medizintechnik und Technomathematik OPUS4-9637 Wissenschaftlicher Artikel Poghossian, Arshak, ; Schöning, Michael Josef, schoening@fh-aachen.de Recent progress in silicon-based biologically sensitive field-effect devices Biologically sensitive field-effect devices (BioFEDs) advantageously combine the electronic field-effect functionality with the (bio)chemical receptor's recognition ability for (bio)chemical sensing. In this review, basic and widely applied device concepts of silicon-based BioFEDs (ion-sensitive field-effect transistor, silicon nanowire transistor, electrolyte-insulator-semiconductor capacitor, light-addressable potentiometric sensor) are presented and recent progress (from 2019 to early 2021) is discussed. One of the main advantages of BioFEDs is the label-free sensing principle enabling to detect a large variety of biomolecules and bioparticles by their intrinsic charge. The review encompasses applications of BioFEDs for the label-free electrical detection of clinically relevant protein biomarkers, deoxyribonucleic acid molecules and viruses, enzyme-substrate reactions as well as recording of the cell acidification rate (as an indicator of cellular metabolism) and the extracellular potential. Amsterdam Elsevier 2021 Current Opinion in Electrochemistry Article number: 100811 10.1016/j.coelec.2021.100811 bezahl https://doi.org/10.1016/j.coelec.2021.100811 Fachbereich Medizintechnik und Technomathematik OPUS4-8594 Wissenschaftlicher Artikel Miyamoto, Koichiro, ; Seki, Kosuke, ; Suto, Takeyuki, ; Werner, Frederik, f.werner@fh-aachen.de; Wagner, Torsten, torsten.wagner@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de; Yoshinobu, Tatsuo, Improved spatial resolution of the chemical imaging sensor with a hybrid illumination that suppresses lateral diffusion of photocarriers The chemical imaging sensor is a semiconductor-based chemical sensor capable of visualizing pH and ion distributions. The spatial resolution depends on the lateral diffusion of photocarriers generated by illumination of the semiconductor substrate. In this study, two types of optical setups, one based on a bundle of optical fibers and the other based on a binocular tube head, were developed to project a hybrid illumination of a modulated light beam and a ring-shaped constant illumination onto the sensor plate. An improved spatial resolution was realized by the ring-shaped constant illumination, which suppressed lateral diffusion of photocarriers by enhanced recombination due to the increased carrier concentration. Amsterdam Elsevier 2018 5 Sensor and Actuators B: Chemical 273 1328 1333 10.1016/j.snb.2018.07.016 bezahl http://doi.org/10.1016/j.snb.2018.07.016 Fachbereich Medizintechnik und Technomathematik OPUS4-8604 Wissenschaftlicher Artikel Rodrigues, Raul T., ; Morais, Paulo V., ; Nordi, Cristina S. F., ; Schöning, Michael Josef, schoening@fh-aachen.de; Siqueira Jr., José R., ; Caseli, Luciano, Carbon Nanotubes and Algal Polysaccharides To Enhance the Enzymatic Properties of Urease in Lipid Langmuir-Blodgett Films Algal polysaccharides (extracellular polysaccharides) and carbon nanotubes (CNTs) were adsorbed on dioctadecyldimethylammonium bromide Langmuir monolayers to serve as a matrix for the incorporation of urease. The physicochemical properties of the supramolecular system as a monolayer at the air-water interface were investigated by surface pressure-area isotherms, surface potential-area isotherms, interfacial shear rheology, vibrational spectroscopy, and Brewster angle microscopy. The floating monolayers were transferred to hydrophilic solid supports, quartz, mica, or capacitive electrolyte-insulator-semiconductor (EIS) devices, through the Langmuir-Blodgett (LB) technique, forming mixed films, which were investigated by quartz crystal microbalance, fluorescence spectroscopy, and field emission gun scanning electron microscopy. The enzyme activity was studied with UV-vis spectroscopy, and the feasibility of the thin film as a urea sensor was essayed in an EIS sensor device. The presence of CNT in the enzyme-lipid LB film not only tuned the catalytic activity of urease but also helped to conserve its enzyme activity. Viability as a urease sensor was demonstrated with capacitance-voltage and constant capacitance measurements, exhibiting regular and distinctive output signals over all concentrations used in this work. These results are related to the synergism between the compounds on the active layer, leading to a surface morphology that allowed fast analyte diffusion owing to an adequate molecular accommodation, which also preserved the urease activity. This work demonstrates the feasibility of employing LB films composed of lipids, CNT, algal polysaccharides, and enzymes as EIS devices for biosensing applications. Washington, DC ACS Publications 2018 11 Langmuir 34 9 3082 3093 10.1021/acs.langmuir.7b04317 campus http://doi.org/10.1021/acs.langmuir.7b04317 Fachbereich Medizintechnik und Technomathematik OPUS4-8605 Buch (Monographie) Schöning, Michael Josef, schoening@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de Label-free biosensing: advanced materials, devices and applications Cham Springer 2018 xii, 480 Seiten ; Illustrationen, Diagramme 978-3-319-75219-8 Fachbereich Medizintechnik und Technomathematik OPUS4-8606 Teil eines Buches Yoshinobu, Tatsuo, ; Krause, Steffi, ; Miyamoto, Ko-ichiro, ; Werner, Frederik, f.werner@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de; Wagner, Torsten, torsten.wagner@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de (Bio-)chemical Sensing and Imaging by LAPS and SPIM The light-addressable potentiometric sensor (LAPS) and scanning photo-induced impedance microscopy (SPIM) are two closely related methods to visualise the distributions of chemical species and impedance, respectively, at the interface between the sensing surface and the sample solution. They both have the same field-effect structure based on a semiconductor, which allows spatially resolved and label-free measurement of chemical species and impedance in the form of a photocurrent signal generated by a scanning light beam. In this article, the principles and various operation modes of LAPS and SPIM, functionalisation of the sensing surface for measuring various species, LAPS-based chemical imaging and high-resolution sensors based on silicon-on-sapphire substrates are described and discussed, focusing on their technical details and prospective applications. Cham Springer 2018 29 Label-free biosensing: advanced materials, devices and applications 978-3-319-75219-8 103 132 campus https://doi.org/10.1007/5346_2017_22 Fachbereich Medizintechnik und Technomathematik OPUS4-8907 Wissenschaftlicher Artikel Poghossian, Arshak, poghossian@fh-aachen.de; Geissler, Hanno, ; Schöning, Michael Josef, schoening@fh-aachen.de Rapid methods and sensors for milk quality monitoring and spoilage detection Amsterdam Elsevier 2019 Biosensors and Bioelectronics 140 Article 111272 10.1016/j.bios.2019.04.040 bezahl https://doi.org/10.1016/j.bios.2019.04.040 Fachbereich Medizintechnik und Technomathematik OPUS4-8894 Wissenschaftlicher Artikel Morais, Paulo V., ; Silva, Anielle C. A., ; Dantas, Noelio O., ; Schöning, Michael Josef, schoening@fh-aachen.de; Siqueira, José R., Jr., Hybrid Layer-by-Layer Film of Polyelectrolytes-Embedded Catalytic CoFe2O4 Nanocrystals as Sensing Units in Capacitive Electrolyte-Insulator-Semiconductor Devices Weinheim Wiley 2019 8 physica status solidi a : applications and materials sciences 216 1900044 1 9 10.1002/pssa.201900044 campus https://doi.org/10.1002/pssa.201900044 Fachbereich Medizintechnik und Technomathematik OPUS4-8859 Wissenschaftlicher Artikel Breuer, Lars, L.Breuer@fh-aachen.de; Pilas, Johanna, pilas@fh-aachen.de; Guthmann, Eric, ; Schöning, Michael Josef, schoening@fh-aachen.de; Thoelen, Ronald, ; Wagner, Torsten, torsten.wagner@fh-aachen.de Towards light-addressable flow control: responsive hydrogels with incorporated graphene oxide as laser-driven actuator structures within microfluidic channels Amsterdam Elsevier 2019 6 Sensor and Actuators B: Chemical 288 579 585 10.1016/j.snb.2019.02.086 bezahl https://doi.org/10.1016/j.snb.2019.02.086 Fachbereich Medizintechnik und Technomathematik OPUS4-9258 Wissenschaftlicher Artikel Dantism, Shahriar, Dantism@fh-aachen.de; Röhlen, Desiree, roehlen@fh-aachen.de; Dahmen, Markus, ; Wagner, Torsten, torsten.wagner@fh-aachen.de; Wagner, Patrick, ; Schöning, Michael Josef, schoening@fh-aachen.de LAPS-based monitoring of metabolic responses of bacterial cultures in a paper fermentation broth As an alternative renewable energy source, methane production in biogas plants is gaining more and more attention. Biomass in a bioreactor contains different types of microorganisms, which should be considered in terms of process-stability control. Metabolically inactive microorganisms within the fermentation process can lead to undesirable, time-consuming and cost-intensive interventions. Hence, monitoring of the cellular metabolism of bacterial populations in a fermentation broth is crucial to improve the biogas production, operation efficiency, and sustainability. In this work, the extracellular acidification of bacteria in a paper-fermentation broth is monitored after glucose uptake, utilizing a differential light-addressable potentiometric sensor (LAPS) system. The LAPS system is loaded with three different model microorganisms (Escherichia coli, Corynebacterium glutamicum, and Lactobacillus brevis) and the effect of the fermentation broth at different process stages on the metabolism of these bacteria is studied. In this way, different signal patterns related to the metabolic response of microorganisms can be identified. By means of calibration curves after glucose uptake, the overall extracellular acidification of bacterial populations within the fermentation process can be evaluated. Amsterdam Elsevier 2020 Sensors and Actuators B: Chemical 320 Art. 128232 10.1016/j.snb.2020.128232 bezahl https://doi.org/10.1016/j.snb.2020.128232 Fachbereich Medizintechnik und Technomathematik OPUS4-9236 Wissenschaftlicher Artikel Muschallik, Lukas, muschallik@fh-aachen.de; Molinnus, Denise, Molinnus@fh-aachen.de; Jablonski, Melanie, m.jablonski@fh-aachen.de; Kipp, Carina Ronja, ; Bongaerts, Johannes, bongaerts@fh-aachen.de; Pohl, Martina, ma.pohl@fz-juelich.de; Wagner, Torsten, torsten.wagner@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de; Selmer, Thorsten, selmer@fh-aachen.de; Siegert, Petra, siegert@fh-aachen.de Synthesis of α-hydroxy ketones and vicinal (R, R)-diols by Bacillus clausii DSM 8716ᵀ butanediol dehydrogenase α-hydroxy ketones (HK) and 1,2-diols are important building blocks for fine chemical synthesis. Here, we describe the R-selective 2,3-butanediol dehydrogenase from B. clausii DSM 8716ᵀ (BcBDH) that belongs to the metal-dependent medium chain dehydrogenases/reductases family (MDR) and catalyzes the selective asymmetric reduction of prochiral 1,2-diketones to the corresponding HK and, in some cases, the reduction of the same to the corresponding 1,2-diols. Aliphatic diketones, like 2,3-pentanedione, 2,3-hexanedione, 5-methyl-2,3-hexanedione, 3,4-hexanedione and 2,3-heptanedione are well transformed. In addition, surprisingly alkyl phenyl dicarbonyls, like 2-hydroxy-1-phenylpropan-1-one and phenylglyoxal are accepted, whereas their derivatives with two phenyl groups are not substrates. Supplementation of Mn²⁺ (1 mM) increases BcBDH's activity in biotransformations. Furthermore, the biocatalytic reduction of 5-methyl-2,3-hexanedione to mainly 5-methyl-3-hydroxy-2-hexanone with only small amounts of 5-methyl-2-hydroxy-3-hexanone within an enzyme membrane reactor is demonstrated. London RSC Publishing 2020 10 RSC Advances 10 12206 12216 10.1039/D0RA02066D weltweit https://doi.org/10.1039/D0RA02066D Fachbereich Chemie und Biotechnologie OPUS4-9238 Wissenschaftlicher Artikel Welden, Rene, welden@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de; Wagner, Patrick H., ; Wagner, Torsten, torsten.wagner@fh-aachen.de Light-Addressable Electrodes for Dynamic and Flexible Addressing of Biological Systems and Electrochemical Reactions In this review article, we are going to present an overview on possible applications of light-addressable electrodes (LAE) as actuator/manipulation devices besides classical electrode structures. For LAEs, the electrode material consists of a semiconductor. Illumination with a light source with the appropiate wavelength leads to the generation of electron-hole pairs which can be utilized for further photoelectrochemical reaction. Due to recent progress in light-projection technologies, highly dynamic and flexible illumination patterns can be generated, opening new possibilities for light-addressable electrodes. A short introduction on semiconductor-electrolyte interfaces with light stimulation is given together with electrode-design approaches. Towards applications, the stimulation of cells with different electrode materials and fabrication designs is explained, followed by analyte-manipulation strategies and spatially resolved photoelectrochemical deposition of different material types. Basel MDPI 2020 21 Sensors 20 Artikel-Nummer 1680 1 22 10.3390/s20061680 weltweit https://doi.org/10.3390/s20061680 Fachbereich Medizintechnik und Technomathematik OPUS4-9215 Wissenschaftlicher Artikel Jildeh, Zaid B., ; Kirchner, Patrick, ; Oberländer, Jan, ; Vahidpour, Farnoosh, ; Wagner, Patrick H., ; Schöning, Michael Josef, Development of a package-sterilization process for aseptic filling machines: A numerical approach and validation for surface treatment with hydrogen peroxide Within the present work a sterilization process by a heated gas mixture that contains hydrogen peroxide (H₂O₂) is validated by experiments and numerical modeling techniques. The operational parameters that affect the sterilization efficacy are described alongside the two modes of sterilization: gaseous and condensed H₂O₂. Measurements with a previously developed H₂O₂ gas sensor are carried out to validate the applied H₂O₂ gas concentration during sterilization. We performed microbiological tests at different H₂O₂ gas concentrations by applying an end-point method to carrier strips, which contain different inoculation loads of Geobacillus stearothermophilus spores. The analysis of the sterilization process of a pharmaceutical glass vial is performed by numerical modeling. The numerical model combines heat- and advection-diffusion mass transfer with vapor-pressure equations to predict the location of condensate formation and the concentration of H₂O₂ at the packaging surfaces by changing the gas temperature. For a sterilization process of 0.7 s, a H₂O₂ gas concentration above 4% v/v is required to reach a log-count reduction above six. The numerical results showed the location of H₂O₂ condensate formation, which decreases with increasing sterilant-gas temperature. The model can be transferred to different gas nozzle- and packaging geometries to assure the absence of H₂O₂ residues. Amsterdam Elsevier 2020 Sensor and Actuators A: Physical 303 111691 10.1016/j.sna.2019.111691 bezahl https://doi.org/10.1016/j.sna.2019.111691 Fachbereich Medizintechnik und Technomathematik OPUS4-9538 Wissenschaftlicher Artikel Jildeh, Zaid B., ; Wagner, Patrick H., ; Schöning, Michael Josef, schoening@fh-aachen.de Sterilization of Objects, Products, and Packaging Surfaces and Their Characterization in Different Fields of Industry: The Status in 2020 The treatment method to deactivate viable microorganisms from objects or products is termed sterilization. There are multiple forms of sterilization, each intended to be applied for a specific target, which depends on—but not limited to—the thermal, physical, and chemical stability of that target. Herein, an overview on the currently used sterilization processes in the global market is provided. Different sterilization techniques are grouped under a category that describes the method of treatment: radiation (gamma, electron beam, X-ray, and ultraviolet), thermal (dry and moist heat), and chemical (ethylene oxide, ozone, chlorine dioxide, and hydrogen peroxide). For each sterilization process, the typical process parameters as defined by regulations and the mode of antimicrobial activity are summarized. Finally, the recommended microorganisms that are used as biological indicators to validate sterilization processes in accordance with the rules that are established by various regulatory agencies are summarized. Weinheim Wiley-VCH 2021 27 Seiten physica status solidi (a) applications and materials science 218 Corresponding author: Michael J. Schöning 13 10.1002/pssa.202000732 weltweit https://doi.org/10.1002/pssa.202000732 Fachbereich Medizintechnik und Technomathematik OPUS4-9543 Wissenschaftlicher Artikel Molinnus, Denise, Molinnus@fh-aachen.de; Drinic, Aleksander, ; Iken, Heiko, iken@fh-aachen.de; Kröger, Nadja, ; Zinser, Max, ; Smeets, Ralf, ; Köpf, Marius, ; Kopp, Alexander, ; Schöning, Michael Josef, schoening@fh-aachen.de Towards a flexible electrochemical biosensor fabricated from biocompatible Bombyx mori silk Amsterdam Elsevier 2021 Biosensors and Bioelectronics 183 Art. 113204 10.1016/j.bios.2021.113204 bezahl https://doi.org/10.1016/j.bios.2021.113204 Fachbereich Medizintechnik und Technomathematik OPUS4-9536 Wissenschaftlicher Artikel Yoshinobu, Tatsuo, ; Schöning, Michael Josef, schoening@fh-aachen.de Light-addressable potentiometric sensors (LAPS) for cell monitoring and biosensing Amsterdam Elsevier 2021 Current Opinion in Electrochemistry In Press, Journal Pre-proof 10.1016/j.coelec.2021.100727 bezahl https://doi.org/10.1016/j.coelec.2021.100727 Fachbereich Medizintechnik und Technomathematik OPUS4-9498 Wissenschaftlicher Artikel Givanoudi, Stella, ; Cornelis, Peter, ; Rasschaert, Geertrui, ; Wackers, Gideon, ; Iken, Heiko, iken@fh-aachen.de; Rolka, David, d.rolka@fh-aachen.de; Yongabi, Derick, ; Robbens, Johan, ; Schöning, Michael Josef, schoening@fh-aachen.de; Heyndrickx, Marc, ; Wagner, Patrick, Selective Campylobacter detection and quantification in poultry: A sensor tool for detecting the cause of a common zoonosis at its source Amsterdam Elsevier 2021 Sensors and Actuators B: Chemical In Press, Journal Pre-proof Article 129484 10.1016/j.snb.2021.129484 bezahl https://doi.org/10.1016/j.snb.2021.129484 Fachbereich Medizintechnik und Technomathematik OPUS4-9956 Wissenschaftlicher Artikel Molinnus, Denise, Molinnus@fh-aachen.de; Iken, Heiko, iken@fh-aachen.de; Johnen, Anna Lynn, ; Richstein, Benjamin, ; Hellmich, Lena, ; Poghossian, Arshak, ; Knoch, Joachim, ; Schöning, Michael Josef, schoening@fh-aachen.de Miniaturized pH-Sensitive Field-Effect Capacitors with Ultrathin Ta₂O₅ Films Prepared by Atomic Layer Deposition Miniaturized electrolyte-insulator-semiconductor capacitors (EISCAPs) with ultrathin gate insulators have been studied in terms of their pH-sensitive sensor characteristics: three different EISCAP systems consisting of Al-p-Si-Ta2O5(5 nm), Al-p-Si-Si3N4(1 or 2 nm)-Ta2O5 (5 nm), and Al-p-Si-SiO2(3.6 nm)-Ta2O5(5 nm) layer structures are characterized in buffer solution with different pH values by means of capacitance-voltage and constant capacitance method. The SiO2 and Si3N4 gate insulators are deposited by rapid thermal oxidation and rapid thermal nitridation, respectively, whereas the Ta2O5 film is prepared by atomic layer deposition. All EISCAP systems have a clear pH response, favoring the stacked gate insulators SiO2-Ta2O5 when considering the overall sensor characteristics, while the Si3N4(1 nm)-Ta2O5 stack delivers the largest accumulation capacitance (due to the lower equivalent oxide thickness) and a higher steepness in the slope of the capacitance-voltage curve among the studied stacked gate insulator systems. Weinheim Wiley-VCH 2022 7 Seiten physica status solidi (a) applications and materials science 219 8 10.1002/pssa.202100660 weltweit https://doi.org/10.1002/pssa.202100660 Fachbereich Medizintechnik und Technomathematik OPUS4-9957 Wissenschaftlicher Artikel Oliveira, Danilo A., ; Molinnus, Denise, Molinnus@fh-aachen.de; Beging, Stefan, beging@fh-aachen.de; Siqueira Jr, José R., ; Schöning, Michael Josef, schoening@fh-aachen.de Biosensor Based on Self-Assembled Films of Graphene Oxide and Polyaniline Using a Field-Effect Device Platform A new functionalization method to modify capacitive electrolyte-insulator-semiconductor (EIS) structures with nanofilms is presented. Layers of polyallylamine hydrochloride (PAH) and graphene oxide (GO) with the compound polyaniline:poly(2-acrylamido-2-methyl-1-propanesulfonic acid) (PANI:PAAMPSA) are deposited onto a p-Si/SiO2 chip using the layer-by-layer technique (LbL). Two different enzymes (urease and penicillinase) are separately immobilized on top of a five-bilayer stack of the PAH:GO/PANI:PAAMPSA-modified EIS chip, forming a biosensor for detection of urea and penicillin, respectively. Electrochemical characterization is performed by constant capacitance (ConCap) measurements, and the film morphology is characterized by atomic force microscopy (AFM) and scanning electron microscopy (SEM). An increase in the average sensitivity of the modified biosensors (EIS-nanofilm-enzyme) of around 15% is found in relation to sensors, only carrying the enzyme but without the nanofilm (EIS-enzyme). In this sense, the nanofilm acts as a stable bioreceptor onto the EIS chip improving the output signal in terms of sensitivity and stability. Weinheim Wiley-VCH 2021 8 physica status solidi (a) applications and materials science 218 Corresponding author: José R. Siqueira Jr & Michael J. Schöning 13 1 9 10.1002/pssa.202000747 weltweit https://doi.org/10.1002/pssa.202000747 Fachbereich Medizintechnik und Technomathematik OPUS4-9958 Wissenschaftlicher Artikel Welden, Rene, welden@fh-aachen.de; Nagamine Komesu, Cindy A., ; Wagner, Patrick H., ; Schöning, Michael Josef, schoening@fh-aachen.de; Wagner, Torsten, torsten.wagner@fh-aachen.de Photoelectrochemical enzymatic penicillin biosensor: A proof-of-concept experiment Photoelectrochemical (PEC) biosensors are a rather novel type of biosensors thatutilizelighttoprovideinformationaboutthecompositionofananalyte,enablinglight-controlled multi-analyte measurements. For enzymatic PEC biosensors,amperometric detection principles are already known in the literature. In con-trast, there is only a little information on H+-ion sensitive PEC biosensors. Inthis work, we demonstrate the detection of H+ions emerged by H+-generatingenzymes, exemplarily demonstrated with penicillinase as a model enzyme on atitanium dioxide photoanode. First, we describe the pH sensitivity of the sensorand study possible photoelectrocatalytic reactions with penicillin. Second, weshow the enzymatic PEC detection of penicillin. Weinheim Wiley-VCH 2021 4 Electrochemical Science Advances 2 Corresponding auhtor: Michael J. Schöning 4 1 5 10.1002/elsa.202100131 weltweit https://doi.org/10.1002/elsa.202100131 Fachbereich Medizintechnik und Technomathematik OPUS4-10467 Wissenschaftlicher Artikel Poghossian, Arshak, ; Welden, Rene, ; Buniatyan, Vahe V., ; Schöning, Michael Josef, An Array of On-Chip Integrated, Individually Addressable Capacitive Field-Effect Sensors with Control Gate: Design and Modelling The on-chip integration of multiple biochemical sensors based on field-effect electrolyte-insulator-semiconductor capacitors (EISCAP) is challenging due to technological difficulties in realization of electrically isolated EISCAPs on the same Si chip. In this work, we present a new simple design for an array of on-chip integrated, individually electrically addressable EISCAPs with an additional control gate (CG-EISCAP). The existence of the CG enables an addressable activation or deactivation of on-chip integrated individual CG-EISCAPs by simple electrical switching the CG of each sensor in various setups, and makes the new design capable for multianalyte detection without cross-talk effects between the sensors in the array. The new designed CG-EISCAP chip was modelled in so-called floating/short-circuited and floating/capacitively-coupled setups, and the corresponding electrical equivalent circuits were developed. In addition, the capacitance-voltage curves of the CG-EISCAP chip in different setups were simulated and compared with that of a single EISCAP sensor. Moreover, the sensitivity of the CG-EISCAP chip to surface potential changes induced by biochemical reactions was simulated and an impact of different parameters, such as gate voltage, insulator thickness and doping concentration in Si, on the sensitivity has been discussed. Basel MDPI 2021 17 Seiten Sensors 21 This article belongs to the Special Issue "Field-Effect Sensors: From pH Sensing to Biosensing" 18 10.3390/s21186161 weltweit https://doi.org/10.3390/s21186161 INB - Institut für Nano- und Biotechnologien OPUS4-10454 Wissenschaftlicher Artikel Vahidpour, Farnoosh, vahidpour@fh-aachen.de; Alghazali, Yousef, ; Akca, Sevilay, ; Hommes, Gregor, ; Schöning, Michael Josef, schoening@fh-aachen.de An Enzyme-Based Interdigitated Electrode-Type Biosensor for Detecting Low Concentrations of H₂O₂ Vapor/Aerosol This work introduces a novel method for the detection of H₂O₂ vapor/aerosol of low concentrations, which is mainly applied in the sterilization of equipment in medical industry. Interdigitated electrode (IDE) structures have been fabricated by means of microfabrication techniques. A differential setup of IDEs was prepared, containing an active sensor element (active IDE) and a passive sensor element (passive IDE), where the former was immobilized with an enzymatic membrane of horseradish peroxidase that is selective towards H₂O₂. Changes in the IDEs' capacitance values (active sensor element versus passive sensor element) under H₂O₂ vapor/aerosol atmosphere proved the detection in the concentration range up to 630 ppm with a fast response time (<60 s). The influence of relative humidity was also tested with regard to the sensor signal, showing no cross-sensitivity. The repeatability assessment of the IDE biosensors confirmed their stable capacitive signal in eight subsequent cycles of exposure to H₂O₂ vapor/aerosol. Room-temperature detection of H₂O₂ vapor/aerosol with such miniaturized biosensors will allow a future three-dimensional, flexible mapping of aseptic chambers and help to evaluate sterilization assurance in medical industry. Basel MDPI 2022 18 Seiten Chemosensors 10 This article belongs to the Special Issue "Bioinspired Chemical Sensors and Micro-Nano Devices" 6 10.3390/chemosensors10060202 https://doi.org/10.3390/chemosensors10060202 INB - Institut für Nano- und Biotechnologien OPUS4-10456 Wissenschaftlicher Artikel Poghossian, Arshak, ; Karschuck, Tobias, karschuck@fh-aachen.de; Wagner, Patrick, ; Schöning, Michael Josef, schoening@fh-aachen.de Field-Effect Capacitors Decorated with Ligand-Stabilized Gold Nanoparticles: Modeling and Experiments Nanoparticles are recognized as highly attractive tunable materials for designing field-effect biosensors with enhanced performance. In this work, we present a theoretical model for electrolyte-insulator-semiconductor capacitors (EISCAP) decorated with ligand-stabilized charged gold nanoparticles. The charged AuNPs are taken into account as additional, nanometer-sized local gates. The capacitance-voltage (C-V) curves and constant-capacitance (ConCap) signals of the AuNP-decorated EISCAPs have been simulated. The impact of the AuNP coverage on the shift of the C-V curves and the ConCap signals was also studied experimentally on Al-p-Si-SiO₂ EISCAPs decorated with positively charged aminooctanethiol-capped AuNPs. In addition, the surface of the EISCAPs, modified with AuNPs, was characterized by scanning electron microscopy for different immobilization times of the nanoparticles. Basel MDPI 2022 14 Seiten Biosensors 12 This article belongs to the Special Issue "Biosensors in Nanotechnology" 5 10.3390/bios12050334 weltweit https://doi.org/10.3390/bios12050334 INB - Institut für Nano- und Biotechnologien OPUS4-10458 Wissenschaftlicher Artikel Karschuck, Tobias, ; Kaulen, Corinna, ; Poghossian, Arshak, ; Wagner, Patrick H., ; Schöning, Michael Josef, schoening@fh-aachen.de Gold nanoparticle-modified capacitive field-effect sensors: Studying the surface density of nanoparticles and coupling of charged polyelectrolyte macromolecules The coupling of ligand-stabilized gold nanoparticles with field-effect devices offers new possibilities for label-free biosensing. In this work, we study the immobilization of aminooctanethiol-stabilized gold nanoparticles (AuAOTs) on the silicon dioxide surface of a capacitive field-effect sensor. The terminal amino group of the AuAOT is well suited for the functionalization with biomolecules. The attachment of the positively-charged AuAOTs on a capacitive field-effect sensor was detected by direct electrical readout using capacitance-voltage and constant capacitance measurements. With a higher particle density on the sensor surface, the measured signal change was correspondingly more pronounced. The results demonstrate the ability of capacitive field-effect sensors for the non-destructive quantitative validation of nanoparticle immobilization. In addition, the electrostatic binding of the polyanion polystyrene sulfonate to the AuAOT-modified sensor surface was studied as a model system for the label-free detection of charged macromolecules. Most likely, this approach can be transferred to the label-free detection of other charged molecules such as enzymes or antibodies. Weinheim Wiley-VCH 2021 10 Seiten Electrochemical Science Advances 2 5 10.1002/elsa.202100179 weltweit https://doi.org/10.1002/elsa.202100179 INB - Institut für Nano- und Biotechnologien OPUS4-10462 Wissenschaftlicher Artikel Vahidpour, Farnoosh, ; Guthman, Eric, ; Arreola, Julia, ; Alghazali, Yousef H. M., ; Wagner, Torsten, ; Schöning, Michael Josef, Assessment of Various Process Parameters for Optimized Sterilization Conditions Using a Multi-Sensing Platform In this study, an online multi-sensing platform was engineered to simultaneously evaluate various process parameters of food package sterilization using gaseous hydrogen peroxide (H₂O₂). The platform enabled the validation of critical aseptic parameters. In parallel, one series of microbiological count reduction tests was performed using highly resistant spores of B. atrophaeus DSM 675 to act as the reference method for sterility validation. By means of the multi-sensing platform together with microbiological tests, we examined sterilization process parameters to define the most effective conditions with regards to the highest spore kill rate necessary for aseptic packaging. As these parameters are mutually associated, a correlation between different factors was elaborated. The resulting correlation indicated the need for specific conditions regarding the applied H₂O₂ gas temperature, the gas flow and concentration, the relative humidity and the exposure time. Finally, the novel multi-sensing platform together with the mobile electronic readout setup allowed for the online and on-site monitoring of the sterilization process, selecting the best conditions for sterility and, at the same time, reducing the use of the time-consuming and costly microbiological tests that are currently used in the food package industry. Basel MDPI 2022 16 Seiten Foods 11 This article belongs to the Special Issue "Sensors and Biosensors Application for Food Industries" 5 10.3390/foods11050660 weltweit https://doi.org/10.3390/foods11050660 INB - Institut für Nano- und Biotechnologien OPUS4-8720 Teil eines Buches Schöning, Michael Josef, schoening@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de Enzyme und Biosensorik Enzymbasierte Biosensoren finden seit mehr als fünf Jahrzehnten einen prosperierenden Wachstumsmarkt und werden zunehmend auch in biotechnologischen Prozessen eingesetzt. In diesem Kapitel werden, ausgehend vom Sensorbegriff und typischen Kenngrößen für Biosensoren (Abschn. 18.1), elektrochemische Enzym-Biosensoren vorgestellt und deren typischen Einsatzgebiete diskutiert (Abschn. 18.2). Ein Blick über den „Tellerrand" hinaus zeigt alternative Transduktorprinzipien (Abschn. 18.3) und führt abschließend in aktuelle Forschungstrends ein (Abschn. 18.4). Berlin Springer Spektrum 2018 24 Einführung in die Enzymtechnologie 978-3-662-57619-9 323 347 10.1007/978-3-662-57619-9_18 campus https://doi.org/10.1007/978-3-662-57619-9_18 Fachbereich Medizintechnik und Technomathematik OPUS4-8976 Wissenschaftlicher Artikel Özsoylu, Dua, ; Kizildag, Sefa, dua.oezsoylu@alumni.fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de; Wagner, Torsten, torsten.wagner@fh-aachen.de Effect of plasma treatment on the sensor properties of a light-addressable potentiometric sensor (LAPS) A light-addressable potentiometric sensor (LAPS) is a field-effect-based (bio-) chemical sensor, in which a desired sensing area on the sensor surface can be defined by illumination. Light addressability can be used to visualize the concentration and spatial distribution of the target molecules, e.g., H+ ions. This unique feature has great potential for the label-free imaging of the metabolic activity of living organisms. The cultivation of those organisms needs specially tailored surface properties of the sensor. O2 plasma treatment is an attractive and promising tool for rapid surface engineering. However, the potential impacts of the technique are carefully investigated for the sensors that suffer from plasma-induced damage. Herein, a LAPS with a Ta2O5 pH-sensitive surface is successfully patterned by plasma treatment, and its effects are investigated by contact angle and scanning LAPS measurements. The plasma duration of 30 s (30 W) is found to be the threshold value, where excessive wettability begins. Furthermore, this treatment approach causes moderate plasma-induced damage, which can be reduced by thermal annealing (10 min at 300 °C). These findings provide a useful guideline to support future studies, where the LAPS surface is desired to be more hydrophilic by O2 plasma treatment. Weinheim Wiley 2019 8 Seiten physica status solidi a : applications and materials sciences 216 Corresponding author: Torsten Wagner 20 10.1002/pssa.201900259 weltweit https://doi.org/10.1002/pssa.201900259 Fachbereich Medizintechnik und Technomathematik OPUS4-8984 Teil eines Buches Schöning, Michael Josef, schoening@fh-aachen.de; Wagner, Torsten, torsten.wagner@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de; Miyamoto, K.I., ; Werner, C.F., ; Krause, S., ; Yoshinobu, T., Light-addressable potentiometric sensors for (bio-)chemical sensing and imaging Amsterdam Elsevier 2018 13 Encyclopedia of Interfacial Chemistry: Surface Science and Electrochemistry. Vol. 7 9780128097397 295 308 https://ebookcentral.proquest.com/lib/aachen/detail.action?docID=5345308 Fachbereich Medizintechnik und Technomathematik OPUS4-8972 Wissenschaftlicher Artikel Dantism, Shahriar, Dantism@fh-aachen.de; Röhlen, Desiree, roehlen@fh-aachen.de; Selmer, Thorsten, selmer@fh-aachen.de; Wagner, Torsten, torsten.wagner@fh-aachen.de; Wagner, Patrick, ; Schöning, Michael Josef, schoening@fh-aachen.de Quantitative differential monitoring of the metabolic activity of Corynebacterium glutamicum cultures utilizing a light-addressable potentiometric sensor system Amsterdam Elsevier 2019 Biosensors and Bioelectronics 139 111332 10.1016/j.bios.2019.111332 bezahl https://doi.org/10.1016/j.bios.2019.111332 Fachbereich Medizintechnik und Technomathematik OPUS4-8973 Wissenschaftlicher Artikel Iken, Heiko, iken@fh-aachen.de; Bronder, Thomas, bronder@fh-aachen.de; Goretzki, Alexander, ; Kriesel, Jana, ; Ahlborn, Kristina, ; Gerlach, Frank, ; Vonau, Winfried, ; Zander, Willi, ; Schubert, Jürgen, ; Schöning, Michael Josef, schoening@fh-aachen.de Development of a Combined pH- and Redox-Sensitive Bi-Electrode Glass Thin-Film Sensor Weinheim Wiley 2019 7 physica status solidi a : applications and materials sciences 216 12 1 8 10.1002/pssa.201900114 campus https://doi.org/10.1002/pssa.201900114 Fachbereich Medizintechnik und Technomathematik OPUS4-9012 Wissenschaftlicher Artikel Jildeh, Zaid B., ; Kirchner, Patrick, ; Baltes, Klaus, ; Wagner, Patrick H., ; Schöning, Michael Josef, schoening@fh-aachen.de Development of an in-line evaporation unit for the production of gas mixtures containing hydrogen peroxide - numerical modeling and experimental results 2019 International Journal of Heat and Mass Transfer 143 Article number 118519 10.1016/j.ijheatmasstransfer.2019.118519 bezahl https://doi.org/10.1016/j.ijheatmasstransfer.2019.118519 Fachbereich Medizintechnik und Technomathematik OPUS4-9332 Wissenschaftlicher Artikel Özsoylu, Dua, oezsoylu@fh-aachen.de; Kizildag, Sefa, ; Schöning, Michael Josef, schoening@fh-aachen.de; Wagner, Torsten, torsten.wagner@fh-aachen.de Differential chemical imaging of extracellular acidification within microfluidic channels using a plasma-functionalized light-addressable potentiometric sensor (LAPS) Extracellular acidification is a basic indicator for alterations in two vital metabolic pathways: glycolysis and cellular respiration. Measuring these alterations by monitoring extracellular acidification using cell-based biosensors such as LAPS plays an important role in studying these pathways whose disorders are associated with numerous diseases including cancer. However, the surface of the biosensors must be specially tailored to ensure high cell compatibility so that cells can represent more in vivo-like behavior, which is critical to gain more realistic in vitro results from the analyses, e.g., drug discovery experiments. In this work, O2 plasma patterning on the LAPS surface is studied to enhance surface features of the sensor chip, e.g., wettability and biofunctionality. The surface treated with O2 plasma for 30 s exhibits enhanced cytocompatibility for adherent CHO-K1 cells, which promotes cell spreading and proliferation. The plasma-modified LAPS chip is then integrated into a microfluidic system, which provides two identical channels to facilitate differential measurements of the extracellular acidification of CHO-K1 cells. To the best of our knowledge, it is the first time that extracellular acidification within microfluidic channels is quantitatively visualized as differential (bio-)chemical images. Amsterdam Elsevier 2020 8 Physics in Medicine 10 100030 10.1016/j.phmed.2020.100030 weltweit https://doi.org/10.1016/j.phmed.2020.100030 Fachbereich Medizintechnik und Technomathematik OPUS4-9372 Wissenschaftlicher Artikel Muschallik, Lukas, muschallik@fh-aachen.de; Kipp, Carina Ronja, ; Recker, Inga, ; Bongaerts, Johannes, bongaerts@fh-aachen.de; Pohl, Martina, ; Gelissen, Melanie, gellissen@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de; Selmer, Thorsten, selmer@fh-aachen.de; Siegert, Petra, siegert@fh-aachen.de Synthesis of α-hydroxy ketones and vicinal diols with the Bacillus licheniformis DSM 13T butane-2, 3-diol dehydrogenase The enantioselective synthesis of α-hydroxy ketones and vicinal diols is an intriguing field because of the broad applicability of these molecules. Although, butandiol dehydrogenases are known to play a key role in the production of 2,3-butandiol, their potential as biocatalysts is still not well studied. Here, we investigate the biocatalytic properties of the meso-butanediol dehydrogenase from Bacillus licheniformis DSM 13T (BlBDH). The encoding gene was cloned with an N-terminal StrepII-tag and recombinantly overexpressed in E. coli. BlBDH is highly active towards several non-physiological diketones and α-hydroxyketones with varying aliphatic chain lengths or even containing phenyl moieties. By adjusting the reaction parameters in biotransformations the formation of either the α-hydroxyketone intermediate or the diol can be controlled. Amsterdam Elsevier 2020 9 Journal of Biotechnology 202 2590-1559 Vol. 324 61 70 10.1016/j.jbiotec.2020.09.016 bezahl https://doi.org/10.1016/j.jbiotec.2020.09.016 Fachbereich Chemie und Biotechnologie OPUS4-3985 Wissenschaftlicher Artikel Poghossian, Arshak, poghossian@fh-aachen.de; Krämer, Melina, ; Abouzar, Maryam H., ; Pita, Marcos, ; Katz, Evgeny, ; Schöning, Michael Josef, schoening@fh-aachen.de Interfacing of biocomputing systems with silicon chips: Enzyme logic gates based on field-effect devices Amsterdam Elsevier 2009 3 Procedia Chemistry. 1 (2009), H. 1 1876-6196 Proceedings of the Eurosensors XXIII conference ; Eurosensors 23 682 685 campus http://dx.doi.org/10.1016/j.proche.2009.07.170 Fachbereich Medizintechnik und Technomathematik OPUS4-3864 Wissenschaftlicher Artikel Näther, Niko, naether@fh-aachen.de; Henkel, Hartmut, ; Schneider, Andreas, ; Schöning, Michael Josef, schoening@fh-aachen.de Investigation of different catalytically active and passive materials for realising a hydrogen peroxide gas sensor Weinheim Wiley 2009 5 physica status solidi (a) . 206 (2009), H. 3 1862-6319 Special Issue: Engineering of Functional Interfaces (EnFI 08) 449 454 campus http://dx.doi.org/10.1002/pssa.200880487 Fachbereich Medizintechnik und Technomathematik OPUS4-4851 Wissenschaftlicher Artikel Schusser, Sebastian, schusser@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de; Bäcker, Matthias, baecker@fh-aachen.de; Leinhos, Marcel, leinhos@fh-aachen.de; Wagner, Patrick, ; Schöning, Michael Josef, schoening@fh-aachen.de Characterization of biodegradable polymers with capacitive field-effect sensors In vitro studies of the degradation kinetic of biopolymers are essential for the design and optimization of implantable biomedical devices. In the presented work, a field-effect capacitive sensor has been applied for the real-time and in situ monitoring of degradation processes of biopolymers for the first time. The polymer-covered field-effect sensor is, in principle, capable to detect any changes in bulk, surface and interface properties of the polymer induced by degradation processes. The feasibility of this approach has been experimentally proven by using the commercially available biomedical polymer poly(D,L-lactic acid) (PDLLA) as a model system. PDLLA films of different thicknesses were deposited on the Ta₂O₅-gate surface of the field-effect structure from a polymer solution by means of spin-coating method. The polymer-modified field-effect sensors have been characterized by means of capacitance-voltage and impedance-spectroscopy method. The degradation of the PDLLA was accelerated by changing the degradation medium from neutral (pH 7.2) to alkaline (pH 9) condition, resulting in drastic changes in the capacitance and impedance spectra of the polymer-modified field-effect sensor. Amsterdam Elsevier 2012 5 Sensors and actuators B: Chemical 187 Part of special issue "Selected Papers from the 14th International Meeting on Chemical Sensors" 2 7 10.1016/j.snb.2012.07.099 campus https://doi.org/10.1016/j.snb.2012.07.099 Fachbereich Medizintechnik und Technomathematik OPUS4-4850 Wissenschaftlicher Artikel Miyamoto, Ko-ichiro, ; Kaneko, Kazumi, ; Matsuo, Akira, ; Wagner, Torsten, torsten.wagner@fh-aachen.de; Kanoh, Shiníchiro, ; Schöning, Michael Josef, schoening@fh-aachen.de; Yoshinobu, Tatsuo, Miniaturized chemical imaging sensor system using an OLED display panel The chemical imaging sensor is a semiconductor-based chemical sensor that can visualize the two-dimensional distribution of specific ions or molecules in the solution. In this study, we developed a miniaturized chemical imaging sensor system with an OLED display panel as a light source that scans the sensor plate. In the proposed configuration, the display panel is placed directly below the sensor plate and illuminates the back surface. The measured area defined by illumination can be arbitrarily customized to fit the size and the shape of the sample to be measured. The waveform of the generated photocurrent, the current-voltage characteristics and the pH sensitivity were investigated and pH imaging with this miniaturized system was demonstrated. Amsterdam Elsevier 2012 5 Sensors and Actuators B: Chemical 170 Part of special issue "Eurosensors XXIV, 2010" 82 87 10.1016/j.snb.2011.02.029 campus https://doi.org/10.1016/j.snb.2011.02.029 Fachbereich Medizintechnik und Technomathematik OPUS4-3886 Wissenschaftlicher Artikel Siqueira, Jose R., ; Werner, Frederik, f.werner@fh-aachen.de; Bäcker, Matthias, baecker@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de; Zucolotto, Valtencir, ; Oliveira, Osvaldo N. Jr., ; Schöning, Michael Josef, schoening@fh-aachen.de Layer-by-Layer Assembly of Carbon Nanotubes Incorporated in Light-Addressable Potentiometric Sensors Washington, DC American Chemical Society 2009 5 Journal of Physical Chemistry C. 113 (2009), H. 33 1932-7455 14765 14770 campus http://pubs.acs.org/doi/abs/10.1021/jp904777t Fachbereich Medizintechnik und Technomathematik OPUS4-4809 Wissenschaftlicher Artikel Spelthahn, Heiko, spelthahn@fh-aachen.de; Schubert, Jürgen, ; Schöning, Michael Josef, schoening@fh-aachen.de Dünnschichtsensoren für die Schwermetallanalytik Die Detektion von Schadstoffen repräsentiert in der Umweltanalytik eine wichtige Aufgabenstellung. Gerade die Abwasser- bzw. Brauchwasseranalytik sowie die Prozesskontrolle haben einen hohen Stellenwert. Siliziumbasierte Dünnschichtsensoren bieten eine kostengünstige Möglichkeit, „online"-Messungen bzw. Vor-Ort-Messungen zeitnah durchzuführen. In dieser Arbeit wird ein potentiometrisches Sensorarray auf der Basis von Chalkogenidgläsern zur Detektion von Schwermetallen in wässrigen Medien vorgestellt. Weinheim Wiley-VCH 2012 2 GIT : Labor-Fachzeitschrift 56 4 285 287 weltweit http://www.git-labor.de/forschung/umwelt/duennschichtsensoren-fuer-die-schwermetallanalytik Fachbereich Medizintechnik und Technomathematik OPUS4-4787 Wissenschaftlicher Artikel Bohrn, U., ; Stütz, E., ; Fuchs, K., ; Fleischer, M., ; Schöning, Michael Josef, schoening@fh-aachen.de; Wagner, P., Monitoring of irritant gas using a whole-cell-based sensor system Cell-based sensors for the detection of gases have long been underrepresented, due to the cellular requirement of being cultured in a liquid environment. In this work we established a cell-based gas biosensor for the detection of toxic substances in air, by adapting a commercial sensor chip (Bionas®), previously used for the measurement of pollutants in liquids. Cells of the respiratory tract (A549, RPMI 2650, V79), which survive at a gas phase in a natural context, are used as biological receptors. The physiological cell parameters acidification, respiration and morphology are continuously monitored in parallel. Ammonia was used as a highly water-soluble model gas to test the feasibility of the sensor system. Infrared measurements confirmed the sufficiency of the medium draining method. This sensor system provides a basis for many sensor applications such as environmental monitoring, building technology and public security. Amsterdam Elsevier 2012 9 Sensors and Actuators B: Chemical 175 208 217 10.1016/j.snb.2012.05.088 campus https://doi.org/10.1016/j.snb.2012.05.088 Fachbereich Medizintechnik und Technomathematik