Dokument-ID Dokumenttyp Verfasser/Autoren Herausgeber Haupttitel Abstract Auflage Verlagsort Verlag Erscheinungsjahr Seitenzahl Schriftenreihe Titel Schriftenreihe Bandzahl ISBN Quelle der Hochschulschrift Konferenzname Bemerkung Quelle:Titel Quelle:Jahrgang Quelle:Heftnummer Quelle:Erste Seite Quelle:Letzte Seite URN DOI Zugriffsart Link Abteilungen OPUS4-10492 Konferenzveröffentlichung Šakić, Bogdan, ; Milijaš, Aleksa, ; Marinković, Marko, ; Butenweg, Christoph, Christoph.Butenweg@fh-aachen.de; Klinkel, Sven, Papadrakakis, Manolis; Fragiadakis, Michalis Influence of prior in-plane damage on the out-of-plane response of non-load bearing unreinforced masonry walls under seismic load Reinforced concrete frames with masonry infill walls are popular form of construction all over the world as well in seismic regions. While severe earthquakes can cause high level of damage of both reinforced concrete and masonry infills, earthquakes of lower to medium intensity some-times can cause significant level of damage of masonry infill walls. Especially important is the level of damage of face loaded infill masonry walls (out-of-plane direction) as out-of-plane load cannot only bring high level of damage to the wall, it can also be life-threating for the people near the wall. The response in out-of-plane direction directly depends on the prior in-plane damage, as previous investigation shown that it decreases resistance capacity of the in-fills. Behaviour of infill masonry walls with and without prior in-plane load is investigated in the experimental campaign and the results are presented in this paper. These results are later compared with analytical approaches for the out-of-plane resistance from the literature. Conclusions based on the experimental campaign on the influence of prior in-plane damage on the out-of-plane response of infill walls are compared with the conclusions from other authors who investigated the same problematic. Athen National Technical University of Athens 2021 21 Seiten 8th ECCOMAS Thematic Conference on Computational Methods in Structural Dynamics and Earthquake Engineering 9786188507258 COMPDYN 2021 28-30 June 2021, Streamed from Athens, Greece 808 828 10.7712/120121.8527.18913 weltweit https://doi.org/10.7712/120121.8527.18913 Fachbereich Energietechnik OPUS4-10438 Wissenschaftlicher Artikel Šakić, Bogdan, ; Marinković, Marko, ; Butenweg, Christoph, Christoph.Butenweg@fh-aachen.de; Klinkel, Sven, Yang, J. Influence of slab deflection on the out-of-plane capacity of unreinforced masonry partition walls Severe damage of non-structural elements is noticed in previous earthquakes, causing high economic losses and posing a life threat for the people. Masonry partition walls are one of the most commonly used non-structural elements. Therefore, their behaviour under earthquake loading in out-of-plane (OOP) direction is investigated by several researches in the past years. However, none of the existing experimental campaigns or analytical approaches consider the influence of prior slab deflection on OOP response of partition walls. Moreover, none of the existing construction techniques for the connection of partition walls with surrounding reinforced concrete (RC) is investigated for the combined slab deflection and OOP loading. However, the inevitable time-dependent behaviour of RC slabs leads to high values of final slab deflections which can further influence boundary conditions of partition walls. Therefore, a comprehensive study on the influence of slab deflection on the OOP capacity of masonry partitions is conducted. In the first step, experimental tests are carried out. Results of experimental tests are further used for the calibration of the numerical model employed for a parametric study. Based on the results, behaviour under combined loading for different construction techniques is explained. The results show that slab deflection leads either to severe damage or to a high reduction of OOP capacity. Existing practical solutions do not account for these effects. In this contribution, recommendations to overcome the problems of combined slab deflection and OOP loading on masonry partition walls are given. Possible interaction of in-plane (IP) loading, with the combined slab deflection and OOP loading on partition walls, is not investigated in this study. Amsterdam Elsevier 2023 Engineering Structures 276 10.1016/j.engstruct.2022.115342 bezahl https://doi.org/10.1016/j.engstruct.2022.115342 Fachbereich Energietechnik OPUS4-8976 Wissenschaftlicher Artikel Özsoylu, Dua, ; Kizildag, Sefa, dua.oezsoylu@alumni.fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de; Wagner, Torsten, torsten.wagner@fh-aachen.de Effect of plasma treatment on the sensor properties of a light-addressable potentiometric sensor (LAPS) A light-addressable potentiometric sensor (LAPS) is a field-effect-based (bio-) chemical sensor, in which a desired sensing area on the sensor surface can be defined by illumination. Light addressability can be used to visualize the concentration and spatial distribution of the target molecules, e.g., H+ ions. This unique feature has great potential for the label-free imaging of the metabolic activity of living organisms. The cultivation of those organisms needs specially tailored surface properties of the sensor. O2 plasma treatment is an attractive and promising tool for rapid surface engineering. However, the potential impacts of the technique are carefully investigated for the sensors that suffer from plasma-induced damage. Herein, a LAPS with a Ta2O5 pH-sensitive surface is successfully patterned by plasma treatment, and its effects are investigated by contact angle and scanning LAPS measurements. The plasma duration of 30 s (30 W) is found to be the threshold value, where excessive wettability begins. Furthermore, this treatment approach causes moderate plasma-induced damage, which can be reduced by thermal annealing (10 min at 300 °C). These findings provide a useful guideline to support future studies, where the LAPS surface is desired to be more hydrophilic by O2 plasma treatment. Weinheim Wiley 2019 8 Seiten physica status solidi a : applications and materials sciences 216 Corresponding author: Torsten Wagner 20 10.1002/pssa.201900259 weltweit https://doi.org/10.1002/pssa.201900259 Fachbereich Medizintechnik und Technomathematik OPUS4-9332 Wissenschaftlicher Artikel Özsoylu, Dua, oezsoylu@fh-aachen.de; Kizildag, Sefa, ; Schöning, Michael Josef, schoening@fh-aachen.de; Wagner, Torsten, torsten.wagner@fh-aachen.de Differential chemical imaging of extracellular acidification within microfluidic channels using a plasma-functionalized light-addressable potentiometric sensor (LAPS) Extracellular acidification is a basic indicator for alterations in two vital metabolic pathways: glycolysis and cellular respiration. Measuring these alterations by monitoring extracellular acidification using cell-based biosensors such as LAPS plays an important role in studying these pathways whose disorders are associated with numerous diseases including cancer. However, the surface of the biosensors must be specially tailored to ensure high cell compatibility so that cells can represent more in vivo-like behavior, which is critical to gain more realistic in vitro results from the analyses, e.g., drug discovery experiments. In this work, O2 plasma patterning on the LAPS surface is studied to enhance surface features of the sensor chip, e.g., wettability and biofunctionality. The surface treated with O2 plasma for 30 s exhibits enhanced cytocompatibility for adherent CHO-K1 cells, which promotes cell spreading and proliferation. The plasma-modified LAPS chip is then integrated into a microfluidic system, which provides two identical channels to facilitate differential measurements of the extracellular acidification of CHO-K1 cells. To the best of our knowledge, it is the first time that extracellular acidification within microfluidic channels is quantitatively visualized as differential (bio-)chemical images. Amsterdam Elsevier 2020 8 Physics in Medicine 10 100030 10.1016/j.phmed.2020.100030 weltweit https://doi.org/10.1016/j.phmed.2020.100030 Fachbereich Medizintechnik und Technomathematik OPUS4-4652 Wissenschaftlicher Artikel Öhlschläger, Peter, oehlschlaeger@fh-aachen.de; Steinberg, Thorsten, ; Sehr, Peter, ; Osen, Wolfram, Modification of HPV 16 E7 genes: correlation between the level of protein expression and CTL response after immunization of C57BL/6 mice / Steinberg, Thorsten ; Öhlschläger, Peter ; Sehr, Peter ; Osen, Wolfram ; Gissmann, Lutz 2005 8 Vaccine. 23 (2005), H. 9 0264-410X 1149 1157 campus http://dx.doi.org/10.1016/j.vaccine.2004.08.027 Fachbereich Chemie und Biotechnologie OPUS4-4659 Wissenschaftlicher Artikel Öhlschläger, Peter, oehlschlaeger@fh-aachen.de; Spies, Elmar, ; Alvarez, Gerardo, ; Quetting, Michael, ; Groettrup, Marcus, The combination of TLR-9 adjuvantation and electroporation-mediated delivery enhances in vivo antitumor responses after vaccination with HPV-16 E7 encoding DNA Weinheim Wiley 2011 8 International Journal of Cancer. 128 (2011), H. 2 1097-0215 473 481 weltweit http://dx.doi.org/10.1002/ijc.25344 Fachbereich Chemie und Biotechnologie OPUS4-4657 Wissenschaftlicher Artikel Öhlschläger, Peter, oehlschlaeger@fh-aachen.de; Quetting, Michael, ; Alvarez, Gerardo, ; Dürst, Matthias, ; Gissmann, Lutz, ; Kaufmann, Andreas M., Enhancement of immunogenicity of a therapeutic cervical cancer DNA-based vaccine by co-application of sequence-optimized genetic adjuvants Weinheim Wiley 2009 9 International Journal of Cancer 125 1097-0215 1 189 198 campus http://dx.doi.org/10.1002/ijc.24333 Fachbereich Chemie und Biotechnologie OPUS4-4653 Wissenschaftlicher Artikel Öhlschläger, Peter, oehlschlaeger@fh-aachen.de; Pes, Michaela, ; Osen, Wolfram, ; Dürst, Matthias, An improved rearranged Human Papillomavirus Type 16 E7 DNA vaccine candidate (HPV-16 E7SH) induces an E7 wildtype-specific T cell response / Öhlschläger, Peter ; Pes, Michaela ; Osen, Wolfram ; Dürst, Matthias ; Schneider, Achim ; Gissmann, Lutz ; Kaufman 2006 13 Vaccine. 24 (2006), H. 15 0264-410X 2880 2893 campus http://dx.doi.org/10.1016/j.vaccine.2005.12.061 Fachbereich Chemie und Biotechnologie OPUS4-4651 Wissenschaftlicher Artikel Öhlschläger, Peter, oehlschlaeger@fh-aachen.de; Osen, Wolfram, ; Peiler, Tanja, ; Caldeira, Sandra, A DNA vaccine based on a shuffled E7 oncogene of the human papillomavirus type 16 (HPV 16) induces E7-specific cytotoxic T cells but lacks transforming activity / Osen, Wolfram ; Peiler, Tanja ; Öhlschläger, Peter ; Caldeira, Sandra ; Faath, Stefan ; Mich 2001 10 Vaccine. 19 (2001), H. 20 0264-410X 4276 4286 campus http://dx.doi.org/10.1016/S0264-410X(01)00154-2 Fachbereich Chemie und Biotechnologie OPUS4-4655 Wissenschaftlicher Artikel Öhlschläger, Peter, oehlschlaeger@fh-aachen.de; Osen, Wolfram, ; Dell, Kerstin, ; Faath, Stefan, Human papillomavirus type 16 L1 capsomeres induce L1-specific cytotoxic T lymphocytes and tumor regression in C57BL/6 mice / Öhlschläger, Peter ; Osen, Wolfram ; Dell, Kerstin ; Faath, Stefan ; Garcea Robert L: ; Jochmus, Ingrid ; Müller, Martin, Pawlita, 2003 10 Journal of Virology. 77 (2003), H. 8 1098-5514 4635 4645 weltweit http://dx.doi.org/10.1128/​JVI.77.8.4635-4645.2003 Fachbereich Chemie und Biotechnologie