Dokument-ID Dokumenttyp Verfasser/Autoren Herausgeber Haupttitel Abstract Auflage Verlagsort Verlag Erscheinungsjahr Seitenzahl Schriftenreihe Titel Schriftenreihe Bandzahl ISBN Quelle der Hochschulschrift Konferenzname Bemerkung Quelle:Titel Quelle:Jahrgang Quelle:Heftnummer Quelle:Erste Seite Quelle:Letzte Seite URN DOI Zugriffsart Link Abteilungen OPUS4-2008 Wissenschaftlicher Artikel Poghossian, Arshak, poghossian@fh-aachen.de; Berndsen, L., ; Schultze, J. W., ; Lüth, H., ; Schöning, Michael Josef, schoening@fh-aachen.de „High order" hybrid sensor module based on an identical transducer principle Pennington, NJ Electrochemical Society 2001 XVII, 680 S. Chemical and biological sensors and analytical methods : proceedings of the international symposium / Sensor, Physical Electrochemistry, and Organic and Biological Electrochemistry Divisions. Ed.: M. Butler 1-56677-351-2 International Symposium: Chemical and Biological Sensors and Analytical Methods ; (2 : 2001.) 143 152 Fachbereich Medizintechnik und Technomathematik OPUS4-1964 Wissenschaftlicher Artikel Wagner, Torsten, torsten.wagner@fh-aachen.de; Yoshinobu, T., ; Rao, C., ; Otto, R., ; Schöning, Michael Josef, schoening@fh-aachen.de „All-in-one" solid-state device based on a lightaddressable potentiometric sensor platform Piscataway, NJ IEEE Operations Center 2005 3 Transducers '05 : the 13th International Conference on Solid-State Sensors, Actuators and Microsystems ; Seoul, Korea, [June 5 - 9, 2005] ; digest of technical papers / sponsored by Korean Sensors Society. Technical co-sponsors: IEEE Electron Devices Society 0-7803-83995-6 International Conference on Solid State Sensors, Actuators and Microsystems ; (13, 2005, Seoul) 1872 1875 Fachbereich Medizintechnik und Technomathematik OPUS4-3053 Wissenschaftlicher Artikel Wagner, Torsten, torsten.wagner@fh-aachen.de; Rao, C., ; Kloock, Joachim P., kloock@fh-aachen.de; Yoshinobu, T., ; Otto, R., ; Keusgen, M., ; Schöning, Michael Josef, schoening@fh-aachen.de "LAPS Card"—A novel chip card-based light-addressable potentiometric sensor (LAPS) 2006 7 Sensors and Actuators B: Chemical. 118 (2006), H. 1-2 0925-4005 Eurosensors XIX - Eurosensors XIX - The 19th European Conference on Solid-State Transducers 33 40 campus http://dx.doi.org/10.1016/j.snb.2006.04.019 Fachbereich Medizintechnik und Technomathematik OPUS4-4391 Wissenschaftlicher Artikel Werner, Frederik, f.werner@fh-aachen.de; Groebel, Simone, groebel@fh-aachen.de; Wagner, Torsten, torsten.wagner@fh-aachen.de; Yoshinobu, Tatsuo, ; Selmer, Thorsten, selmer@fh-aachen.de; Baumann, Marcus, rektor@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de Überwachung der metabolischen Aktivität von Mikroorganismen zur Kontrolle des biologischen Prozesses im Biogasfermenter Düsseldorf VDI-Verl. 2011 292 S. : Ill., graph. Darst., Kt. Biogas 2011 : Energieträger der Zukunft ; 6. Fachtagung, Fachtagung Braunschweig, 08. und 09. Juni 2011 / VDI Energie und Umwelt 978-3-18-092121-1 Gesellschaft Energie und Umwelt ; Fachtagung Biogas ; (6 : ; 2011.06.08-09 : ; Braunschweig) ; VDI-Berichte ; 2121 285 286 Fachbereich Chemie und Biotechnologie OPUS4-4436 Wissenschaftlicher Artikel Malzahn, Kerstin, ; Windmiller, Joshua Ray, ; Valdés-Ramírez, Gabriela, ; Wang, Joseph, ; Schöning, Michael Josef, schoening@fh-aachen.de Wearable electrochemical sensors for in situ analysis in marine environments Cambridge Royal Society of Chemistry 2011 5 Analyst. 136 (2011), H. 14 0003-2654 2912 2917 campus http://dx.doi.org/10.1039/C1AN15193B Fachbereich Medizintechnik und Technomathematik OPUS4-2010 Wissenschaftlicher Artikel Emons, H., ; Glück, O., ; Schöning, Michael Josef, schoening@fh-aachen.de Voltohmmetry - An alternative detection principle at ultrathin metal electrodes in solution Pennington, NJ Electrochemical Society 2001 XVII, 680 S. Chemical and biological sensors and analytical methods : proceedings of the international symposium / Sensor, Physical Electrochemistry, and Organic and Biological Electrochemistry Divisions. Ed.: M. Butler 1-56677-351-2 International Symposium: Chemical and Biological Sensors and Analytical Methods ; (2 : 2001.) 1 3 Fachbereich Medizintechnik und Technomathematik OPUS4-1811 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Hüllenkremer, B., ; Glück, O., ; Lüth, H., ; Emons, H., Voltohmmetry - a novel sensing principle for heavy metal determination in aqueous solutions 2001 5 Sensors and Actuators B. 78 (2001), H. 1-3 0925-4005 275 280 campus http://dx.doi.org/10.1016/S0925-4005(01)00582-2 Fachbereich Medizintechnik und Technomathematik OPUS4-1863 Wissenschaftlicher Artikel Emons, H., ; Glück, O., ; Hüllenkremer, B., ; Schöning, Michael Josef, schoening@fh-aachen.de Voltohmmetry as an alternative detection method at polycrystalline metal film electrodes 2001 3 Electroanalysis. 13 (2001), H. 8-9 1040-0397 677 680 campus http://www3.interscience.wiley.com/cgi-bin/abstract/82502240/ABSTRACT Fachbereich Medizintechnik und Technomathematik OPUS4-1959 Wissenschaftlicher Artikel Hüllenkremer, B., ; Glück, O., ; Emons, H., ; Lüth, H., ; Schöning, Michael Josef, schoening@fh-aachen.de Voltohmmetrie an polykristallinen Goldelektroden Düsseldorf: VDI-Verl. 2000 1087s.: Ill., graph. Darst. Gesellschaft Mess- und Automatisierungstechnik: Sensoren und Meßsysteme 2000 : Tagung Ludwigsburg, 13. und 14. März 2000 / VDI/VDE-Gesellschaft Meß- und Automatisierungstechnik 3-18-091530-7 VDI-Berichte; 1530 45 54 Fachbereich Medizintechnik und Technomathematik OPUS4-1876 Wissenschaftlicher Artikel Emons, H., ; Baade, A., ; Schöning, Michael Josef, schoening@fh-aachen.de Voltammetric determination of heavy metals in microvolumes of rain water 2000 5 Electroanalysis. 12 (2000), H. 15 1040-0397 1171 1176 campus http://www3.interscience.wiley.com/cgi-bin/abstract/75001059/ABSTRACT Fachbereich Medizintechnik und Technomathematik OPUS4-7724 Wissenschaftlicher Artikel Miyamoto, Ko-ichiro, ; Yu, Bing, ; Isoda, Hiroko, ; Wagner, Torsten, torsten.wagner@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de; Yoshinobu, Tatsuo, Visualization of the recovery process of defects in a cultured cell layer by chemical imaging sensor The chemical imaging sensor is a field-effect sensor which is able to visualize both the distribution of ions (in LAPS mode) and the distribution of impedance (in SPIM mode) in the sample. In this study, a novel cell assay is proposed, in which the chemical imaging sensor operated in SPIM mode is applied to monitor the recovery of defects in a cell layer brought into proximity of the sensing surface. A reduced impedance at a defect formed artificially in a cell layer was successfully visualized in a photocurrent image. The cell layer was cultured over two weeks, during which the temporal change of the photocurrent distribution corresponding to the recovery of the defect was observed. Amsterdam Elsevier 2016 4 Sensors and Actuators B: Chemical 236 965 969 10.1016/j.snb.2016.04.018 bezahl https://doi.org/10.1016/j.snb.2016.04.018 Fachbereich Medizintechnik und Technomathematik OPUS4-6003 Wissenschaftlicher Artikel Miyamoto, Ko-ichiro, ; Hirayama, Yuji, ; Wagner, Torsten, torsten.wagner@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de; Yoshinobu, Tatsuo, Visualization of enzymatic reaction in a microfluidic channel using chemical imaging sensor Amsterdam Elsevier 2013 Electrochimica acta Publ. online campus http://dx.doi.org/10.1016/j.electacta.2013.08.089 Fachbereich Medizintechnik und Technomathematik OPUS4-7337 Wissenschaftlicher Artikel Miyamoto, Ko-ichiro, ; Bing, Yu, ; Wagner, Torsten, torsten.wagner@fh-aachen.de; Yoshinobu, Tatsuo, ; Schöning, Michael Josef, schoening@fh-aachen.de Visualization of Defects on a Cultured Cell Layer by Utilizing Chemical Imaging Sensor Amsterdam Elsevier 2015 3 Procedia Engineering 120 Eurosensors 2015 936 939 10.1016/j.proeng.2015.08.806 Fachbereich Medizintechnik und Technomathematik OPUS4-2410 Wissenschaftlicher Artikel Hoskens, R. C. P., ; Tolstikhin, V.I., ; Förster, Arnold, foerster@fh-aachen.de; Roer, T.G. van de, Vertically integrated transistor-laser structure, take 2 Ann Arbor, Mich. Univ. of Michigan 2000 Getr. Zählung [ca. 200 S.] WOCSDICE 2000, 24th Workshop on Compound Semiconductor Devices and Integrated Circuits held in Europe : May 29 - June 02, 2000, Aegean Sea, Greece. 0970311109 WOCSDICE ; (24, 2000) Workshop on Compound Semiconductor Devices and Integrated Circuits held in Europe ; (24 : ; 2000.05.29-06.02) Fachbereich Energietechnik OPUS4-4857 Wissenschaftlicher Artikel Bohrn, Ulrich, ; Stütz, Evamaria, ; Fleischer, Maximilian, ; Schöning, Michael Josef, schoening@fh-aachen.de; Wagner, Patrick, Using a cell-based gas biosensor for investigation of adverse effects of acetone vapors in vitro Amsterdam Elsevier 2013 7 Biosensors and Bioelectronics. 40 (2013), H. 1 0956-5663 393 400 campus http://dx.doi.org/10.1016/j.bios.2012.08.029 Fachbereich Medizintechnik und Technomathematik OPUS4-2934 Wissenschaftlicher Artikel Mikulics, M., ; Adam, R., ; Kordos, P., ; Förster, Arnold, foerster@fh-aachen.de; Lüth, H., ; Wu, S., ; Zheng, X., ; Sobolewski, R., Ultrafast low-temperature-grown epitaxial GaAs photodetectors transferred on flexible plastic substrates 2005 2 IEEE photonics technology letters : IEEE PTL. 17 (2005), H. 8 1041-1135 1725 1727 campus http://dx.doi.org/10.1109/LPT.2005.851025 Fachbereich Energietechnik OPUS4-1721 Wissenschaftlicher Artikel Näther, Niko, naether@fh-aachen.de; Rolka, David, d.rolka@fh-aachen.de; Poghossian, Arshak, poghossian@fh-aachen.de; Koudelka-Hep, M., ; Schöning, Michael Josef, schoening@fh-aachen.de Two microcell flow-injection analysis (FIA) platforms for capacitive silicon-based field-effect sensors 2005 5 Electrochimica Acta. 51 (2005), H. 5 0013-4686 924 929 10.1016/j.electacta.2005.04.066 campus Fachbereich Medizintechnik und Technomathematik OPUS4-2387 Wissenschaftlicher Artikel Vitusevich, S. A., ; Förster, Arnold, foerster@fh-aachen.de; Indlekofer, K.-M., ; Lüth, H., ; Belyaev, A. E., ; Glavin, B. A., ; Konakova, R. V., Tunneling Through X-Valley-Related Impurity States in GaAs/AlAs Resonant-Tunneling Diodes 2000 6 Physical Review . B. 61 (2000), H. 16 1550-235X 10898 10904 bezahl http://dx.doi.org/10.1103/PhysRevB.61.10898 Fachbereich Energietechnik OPUS4-9211 Wissenschaftlicher Artikel Mennicken, Max, ; Peter, Sophia K., ; Kaulen, Corinna, kaulen@fh-aachen.de; Simon, Ulrich, ; Karthäuser, Silvia, Transport through Redox-Active Ru-Terpyridine Complexes Integrated in Single Nanoparticle Devices Transition metal complexes are electrofunctional molecules due to their high conductivity and their intrinsic switching ability involving a metal-to-ligand charge transfer. Here, a method is presented to contact reliably a few to single redox-active Ru-terpyridine complexes in a CMOS compatible nanodevice and preserve their electrical functionality. Using hybrid materials from 14 nm gold nanoparticles (AuNP) and bis-{4′-[4-(mercaptophenyl)-2,2′:6′,2″-terpyridine]}-ruthenium(II) complexes a device size of 30² nm² inclusive nanoelectrodes is achieved. Moreover, this method bears the opportunity for further downscaling. The Ru-complex AuNP devices show symmetric and asymmetric current versus voltage curves with a hysteretic characteristic in two well separated conductance ranges. By theoretical approximations based on the single-channel Landauer model, the charge transport through the formed double-barrier tunnel junction is thoroughly analyzed and its sensibility to the molecule/metal contact is revealed. It can be verified that tunneling transport through the HOMO is the main transport mechanism while decoherent hopping transport is present to a minor extent. Washington, DC ACS Publications 2020 8 The Journal of Physical Chemistry C 124 8 4881 4889 10.1021/acs.jpcc.9b11716 campus https://doi.org/10.1021/acs.jpcc.9b11716 Fachbereich Medizintechnik und Technomathematik OPUS4-10927 Wissenschaftlicher Artikel Janus, Kevin Alexander, janus@fh-aachen.de; Achtsnicht, Stefan, achtsnicht@fh-aachen.de; Drinic, Aleksander, ; Kopp, Alexander, ; Keusgen, Michael, ; Schöning, Michael Josef, schoening@fh-aachen.de Transient magnesium-based thin-film temperature sensor on a flexible, bioabsorbable substrate for future medical applications In this work, the bioabsorbable materials, namely fibroin, polylactide acid (PLA), magnesium and magnesium oxide are investigated for their application as transient, resistive temperature detectors (RTD). For this purpose, a thin-film magnesium-based meander-like electrode is deposited onto a flexible, bioabsorbable substrate (fibroin or PLA) and encapsulated (passivated) by additional magnesium oxide layers on top and below the magnesium-based electrode. The morphology of different layered RTDs is analyzed by scanning electron microscopy. The sensor performance and lifetime of the RTD is characterized both under ambient atmospheric conditions between 30°C and 43°C, and wet tissue-like conditions with a constant temperature regime of 37°C. The latter triggers the degradation process of the magnesium-based layers. The 3-layers RTDs on a PLA substrate could achieve a lifetime of 8.5 h. These sensors also show the best sensor performance under ambient atmospheric conditions with a mean sensitivity of 0.48 Ω/°C ± 0.01 Ω/°C. Wiley-VCH 2023 22 Seiten Applied Research Corresponding author: Michael Josef Schöning Accepted manuscript 10.1002/appl.202300102 weltweit https://doi.org/10.1002/appl.202300102 Fachbereich Medizintechnik und Technomathematik OPUS4-4375 Wissenschaftlicher Artikel Gun, Jenny, ; Gutkin, Vitaly, ; Lev, Ovadia, ; Boyen, Hans-Gerd, ; Saitner, Marc, ; Wagner, Patrick, ; Olieslaeger, Marc D´, ; Abouzar, Maryam H., ; Poghossian, Arshak, poghossian@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de Tracing gold nanoparticle charge by electrolyte-insulator-semiconductor devices Washington, DC American Cemical Society 2011 6 Journal of Physical Chemistry C. 115 (2011), H. 11 1932-7455 4439 4445 campus http://dx.doi.org/10.1021/jp109886s Fachbereich Medizintechnik und Technomathematik OPUS4-1720 Wissenschaftlicher Artikel Poghossian, Arshak, poghossian@fh-aachen.de; Platen, J., ; Schöning, Michael Josef, schoening@fh-aachen.de Towards self-aligned nanostructures by means of layerexpansion technique 2005 5 Electrochimica Acta. 51 (2005), H. 5 0013-4686 838 843 campus http://dx.doi.org/10.1016/j.electacta.2005.04.065 Fachbereich Medizintechnik und Technomathematik OPUS4-10520 Wissenschaftlicher Artikel Welden, Melanie, ; Poghossian, Arshak, ; Vahidpour, Farnoosh, vahidpour@fh-aachen.de; Wendlandt, Tim, ; Keusgen, Michael, ; Wege, Christina, ; Schöning, Michael Josef, schoening@fh-aachen.de Towards multi-analyte detection with field-effect capacitors modified with tobacco mosaic virus bioparticles as enzyme nanocarriers Utilizing an appropriate enzyme immobilization strategy is crucial for designing enzyme-based biosensors. Plant virus-like particles represent ideal nanoscaffolds for an extremely dense and precise immobilization of enzymes, due to their regular shape, high surface-to-volume ratio and high density of surface binding sites. In the present work, tobacco mosaic virus (TMV) particles were applied for the co-immobilization of penicillinase and urease onto the gate surface of a field-effect electrolyte-insulator-semiconductor capacitor (EISCAP) with a p-Si-SiO₂-Ta₂O₅ layer structure for the sequential detection of penicillin and urea. The TMV-assisted bi-enzyme EISCAP biosensor exhibited a high urea and penicillin sensitivity of 54 and 85 mV/dec, respectively, in the concentration range of 0.1-3 mM. For comparison, the characteristics of single-enzyme EISCAP biosensors modified with TMV particles immobilized with either penicillinase or urease were also investigated. The surface morphology of the TMV-modified Ta₂O₅-gate was analyzed by scanning electron microscopy. Additionally, the bi-enzyme EISCAP was applied to mimic an XOR (Exclusive OR) enzyme logic gate. Basel MDPI 2022 Biosensors 12 This article belongs to the Special Issue "Biosensors: 10th Anniversary Feature Papers" 1 10.3390/bios12010043 weltweit https://doi.org/10.3390/bios12010043 Fachbereich Chemie und Biotechnologie OPUS4-8859 Wissenschaftlicher Artikel Breuer, Lars, L.Breuer@fh-aachen.de; Pilas, Johanna, pilas@fh-aachen.de; Guthmann, Eric, ; Schöning, Michael Josef, schoening@fh-aachen.de; Thoelen, Ronald, ; Wagner, Torsten, torsten.wagner@fh-aachen.de Towards light-addressable flow control: responsive hydrogels with incorporated graphene oxide as laser-driven actuator structures within microfluidic channels Amsterdam Elsevier 2019 6 Sensor and Actuators B: Chemical 288 579 585 10.1016/j.snb.2019.02.086 bezahl https://doi.org/10.1016/j.snb.2019.02.086 Fachbereich Medizintechnik und Technomathematik OPUS4-7289 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Abouzar, Maryam H., ; Ingebrandt, Sven, ; Platen, Johannes, ; Offenhäusser, Andreas, ; Poghossian, Arshak, poghossian@fh-aachen.de Comini, Elisabetta Towards label-free detection of charged macromolecules using field-effect-based structures : Scaling down from capacitive EIS sensor over ISFET to nano-scale devices 2006 5 Nanostructured materials and hybrid composites for gas sensors and biomedical applications : symposium held April 18-20, 2006, San Francisco , California, U.S.A. 9781558998711 Materials Research Society symposia proceedings; v. 915 paper 0915-R05-04 89 94 Fachbereich Medizintechnik und Technomathematik OPUS4-7803 Wissenschaftlicher Artikel Molinnus, Denise, molinnus@fh-aachen.de; Sorich, Maren, ; Bartz, Alexander, ; Siegert, Petra, siegert@fh-aachen.de; Willenberg, Holger S., ; Lisdat, Fred, ; Poghossian, Arshak, poghossian@fh-aachen.de; Keusgen, Michael, ; Schöning, Michael Josef, schoening@fh-aachen.de Towards an adrenaline biosensor based on substrate recycling amplification in combination with an enzyme logic gate An amperometric biosensor using a substrate recycling principle was realized for the detection of low adrenaline concentrations (1 nM) by measurements in phosphate buffer and Ringer's solution at pH 6.5 and pH 7.4, respectively. In proof-of-concept experiments, a Boolean logic-gate principle has been applied to develop a digital adrenaline biosensor based on an enzyme AND logic gate. The obtained results demonstrate that the developed digital biosensor is capable for a rapid qualitative determination of the presence/absence of adrenaline in a YES/NO statement. Such digital biosensor could be used in clinical diagnostics for the control of a correct insertion of a catheter in the adrenal veins during adrenal venous-sampling procedure. Amsterdam Elsevier 2016 5 Sensors and Actuators B: Chemical 237 190 195 10.1016/j.snb.2016.06.064 bezahl https://doi.org/10.4028/10.1016/j.snb.2016.06.064 Fachbereich Chemie und Biotechnologie OPUS4-7940 Wissenschaftlicher Artikel Poghossian, Arshak, poghossian@fh-aachen.de; Werner, Frederik, f.werner@fh-aachen.de; Buniatyan, V. V., ; Wagner, Torsten, torsten.wagner@fh-aachen.de; Miamoto, K., ; Yoshinobu, T., ; Schöning, Michael Josef, schoening@fh-aachen.de Towards addressability of light-addressable potentiometric sensors: Shunting effect of non-illuminated region and cross-talk Amsterdam Elsevier 2017 8 Sensor and Actuators B: Chemical 244 1071 1079 10.1016/j.snb.2017.01.047 Fachbereich Medizintechnik und Technomathematik OPUS4-5122 Wissenschaftlicher Artikel Kirchner, Patrick, kirchner@fh-aachen.de; Oberländer, Jan, oberlaender@fh-aachen.de; Suso, Henri-Pierre, ; Rysstad, Gunnar, ; Keusgen, Michael, ; Schöning, Michael Josef, schoening@fh-aachen.de Towards a wireless sensor system for real-time H2O2 monitoring in aseptic food processes A wireless sensor system based on the industrial ZigBee standard for low-rate wireless networking was developed that enables real-time monitoring of gaseous H2O2 during the package sterilization in aseptic food processes. The sensor system consists of a remote unit connected to a calorimetric gas sensor, which was already established in former works, and an external base unit connected to a laptop computer. The remote unit was built up by an XBee radio frequency (RF) module for data communication and a programmable system-on-chip controller to read out the sensor signal and process the sensor data, whereas the base unit is a second XBee RF module. For the rapid H2O2 detection on various locations inside the package that has to be sterilized, a novel read-out strategy of the calorimetric gas sensor was established, wherein the sensor response is measured within the short sterilization time and correlated with the present H2O2 concentration. In an exemplary measurement application in an aseptic filling machinery, the suitability of the new, wireless sensor system was demonstrated, wherein the influence of the gas velocity on the H2O2 distribution inside a package was determined and verified with microbiological tests. Weinheim Wiley 2013 6 Physica status solidi (a) Vol. 210 Iss. 5 877 883 campus http://dx.doi.org/10.1002/pssa.201200920 Fachbereich Medizintechnik und Technomathematik OPUS4-4366 Wissenschaftlicher Artikel Reisert, Steffen, reisert@fh-aachen.de; Geissler, Hanno, ; Flörke, Rudolf, ; Näther, Niko, naether@fh-aachen.de; Wagner, Patrick, ; Schöning, Michael Josef, schoening@fh-aachen.de Towards a multi-sensor system for the evaluation of aseptic processes employing hydrogen peroxide vapour (H2O2) Weinheim Wiley 2011 5 Physica status solidi (a) : applications and material science. 208 (2011), H. 6 1862-6319 1351 1356 campus http://dx.doi.org/10.1002/pssa.201001138 Fachbereich Medizintechnik und Technomathematik OPUS4-9543 Wissenschaftlicher Artikel Molinnus, Denise, Molinnus@fh-aachen.de; Drinic, Aleksander, ; Iken, Heiko, iken@fh-aachen.de; Kröger, Nadja, ; Zinser, Max, ; Smeets, Ralf, ; Köpf, Marius, ; Kopp, Alexander, ; Schöning, Michael Josef, schoening@fh-aachen.de Towards a flexible electrochemical biosensor fabricated from biocompatible Bombyx mori silk Amsterdam Elsevier 2021 Biosensors and Bioelectronics 183 Art. 113204 10.1016/j.bios.2021.113204 bezahl https://doi.org/10.1016/j.bios.2021.113204 Fachbereich Medizintechnik und Technomathematik OPUS4-1782 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Arzdorf, M., ; Mulchandani, P., ; Chen, W., ; Mulchandani, A., Towards a capacitive enzyme sensor for direct determination of organophosphorus pesticides: Fundamentals studies and aspects of development 2003 8 Sensors. 3 (2003), H. 6 1424-8220 119 127 weltweit http://www.mdpi.net/sensors/papers/s30600119.pdf Fachbereich Medizintechnik und Technomathematik OPUS4-7075 Wissenschaftlicher Artikel Oberländer, Jan, oberlaender@fh-aachen.de; Bromm, Alexander, ; Wendeler, Luisa, ; Iken, Heiko, iken@fh-aachen.de; Palomar Duran, Marlena, ; Greeff, Anton, ; Kirchner, Patrick, kirchner@fh-aachen.de; Keusgen, Michael, ; Schöning, Michael Josef, schoening@fh-aachen.de Towards a biosensor to monitor the sterilisation efficiency of aseptic filling machines Weinheim Wiley 2015 6 Physica status solidi (a) 212 6 1299 1305 10.1002/pssa.201431900 Fachbereich Medizintechnik und Technomathematik OPUS4-6441 Wissenschaftlicher Artikel Takenaga, Shoko, takenaga@fh-aachen.de; Biselli, Manfred, biselli@fh-aachen.de; Schnitzler, Thomas, schnitzler@fh-aachen.de; Öhlschläger, Peter, oehlschlaeger@fh-aachen.de; Wagner, Torsten, torsten.wagner@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de Toward multi-analyte bioarray sensors: LAPS-based on-chip determination of a Michaelis-Menten-like kinetics for cell culturing The metabolic activity of Chinese hamster ovary (CHO) cells was observed using a light-addressable potentiometric sensor (LAPS). The dependency toward different glucose concentrations (17-200 mM) follows a Michaelis-Menten kinetics trajectory with Kₘ = 32.8 mM, and the obtained Kₘ value in this experiment was compared with that found in literature. In addition, the pH shift induced by glucose metabolism of tumor cells transfected with the HPV-16 genome (C3 cells) was successfully observed. These results indicate the possibility to determine the tumor cells metabolism with a LAPS-based measurement device. Weinheim Wiley-VCH 2014 5 Physica status solidi A : Applications and materials science 211 6 1410 1415 10.1002/pssa.201330464 campus https://doi.org/10.1002/pssa.201330464 Fachbereich Chemie und Biotechnologie OPUS4-8787 Wissenschaftlicher Artikel Arreola, Julio, arreola@fh-aachen.de; Keusgen, Michael, ; Schöning, Michael Josef, schoening@fh-aachen.de Toward an immobilization method for spore-based biosensors in oxidative environment Amsterdam Elsevier 2019 7 Electrochimica Acta 302 394 401 10.1016/j.electacta.2019.01.148 bezahl https://doi.org/10.1016/j.electacta.2019.01.148 Fachbereich Medizintechnik und Technomathematik OPUS4-8603 Wissenschaftlicher Artikel Röhlen, Desiree, roehlen@fh-aachen.de; Pilas, Johanna, pilas@fh-aachen.de; Dahmen, Markus, dahmen@fh-aachen.de; Keusgen, Michael, ; Selmer, Thorsten, selmer@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de Toward a Hybrid Biosensor System for Analysis of Organic and Volatile Fatty Acids in Fermentation Processes Monitoring of organic acids (OA) and volatile fatty acids (VFA) is crucial for the control of anaerobic digestion. In case of unstable process conditions, an accumulation of these intermediates occurs. In the present work, two different enzyme-based biosensor arrays are combined and presented for facile electrochemical determination of several process-relevant analytes. Each biosensor utilizes a platinum sensor chip (14 × 14 mm²) with five individual working electrodes. The OA biosensor enables simultaneous measurement of ethanol, formate, d- and l-lactate, based on a bi-enzymatic detection principle. The second VFA biosensor provides an amperometric platform for quantification of acetate and propionate, mediated by oxidation of hydrogen peroxide. The cross-sensitivity of both biosensors toward potential interferents, typically present in fermentation samples, was investigated. The potential for practical application in complex media was successfully demonstrated in spiked sludge samples collected from three different biogas plants. Thereby, the results obtained by both of the biosensors were in good agreement to the applied reference measurements by photometry and gas chromatography, respectively. The proposed hybrid biosensor system was also used for long-term monitoring of a lab-scale biogas reactor (0.01 m³) for a period of 2 months. In combination with typically monitored parameters, such as gas quality, pH and FOS/TAC (volatile organic acids/total anorganic carbonate), the amperometric measurements of OA and VFA concentration could enhance the understanding of ongoing fermentation processes. Lausanne Frontiers 2018 10 Frontiers in Chemistry 6 Article 284 1 11 10.3389/fchem.2018.00284 weltweit http://doi.org/10.3389/fchem.2018.00284 Fachbereich Chemie und Biotechnologie OPUS4-7821 Wissenschaftlicher Artikel Bäcker, Matthias, ; Koch, Claudia, ; Eiben, Sabine, ; Geiger, Fania, ; Eber, Fabian, ; Gliemann, Hartmut, ; Poghossian, Arshak, poghossian@fh-aachen.de; Wege, Christina, ; Schöning, Michael Josef, schoening@fh-aachen.de Tobacco mosaic virus as enzyme nanocarrier for electrochemical biosensors Amsterdam Elsevier 2017 6 Sensors and Actuators B: Chemical 238 716 722 10.1016/j.snb.2016.07.096 Fachbereich Medizintechnik und Technomathematik OPUS4-8429 Teil eines Buches Koch, Claudia, ; Poghossian, Arshak, poghossian@fh-aachen.de; Wege, Christina, ; Schöning, Michael Josef, schoening@fh-aachen.de Wege, Christina TMV-Based Adapter Templates for Enhanced Enzyme Loading in Biosensor Applications Nanotubular tobacco mosaic virus (TMV) particles and RNA-free lower-order coat protein (CP) aggregates have been employed as enzyme carriers in different diagnostic layouts and compared for their influence on biosensor performance. In the following, we describe a label-free electrochemical biosensor for improved glucose detection by use of TMV adapters and the enzyme glucose oxidase (GOD). A specific and efficient immobilization of streptavidin-conjugated GOD ([SA]-GOD) complexes on biotinylated TMV nanotubes or CP aggregates was achieved via bioaffinity binding. Glucose sensors with adsorptively immobilized [SA]-GOD, and with [SA]-GOD cross-linked with glutardialdehyde, respectively, were tested in parallel on the same sensor chip. Comparison of these sensors revealed that TMV adapters enhanced the amperometric glucose detection remarkably, conveying highest sensitivity, an extended linear detection range and fastest response times. These results underline a great potential of an integration of virus/biomolecule hybrids with electronic transducers for applications in biosensorics and biochips. Here, we describe the fabrication and use of amperometric sensor chips combining an array of circular Pt electrodes, their loading with GOD-modified TMV nanotubes (and other GOD immobilization methods), and the subsequent investigations of the sensor performance. New York, NY Humana Press 2018 15 Virus-Derived Nanoparticles for Advanced Technologies 978-1-4939-7808-3 Methods in Molecular Biology, vol 1776 553 568 10.1007/978-1-4939-7808-3 bezahl https://doi.org/10.1007/978-1-4939-7808-3 Fachbereich Medizintechnik und Technomathematik OPUS4-6856 Konferenzveröffentlichung Kloock, Joachim P., kloock@fh-aachen.de; Schubert, J., ; Ermelenko, Y., ; Vlasov, Y. G., ; Bratov, A., ; Schöning, Michael Josef, schoening@fh-aachen.de Thin-film sensors with chalcogenide glass materials - a general survey Warsaw 2006 5 Biochemical sensing utilisation of micro- and nanotechnologies : Warsaw, [23rd - 26th] November 2005 / ed. by M. Mascini ... Lecture notes of the ICB seminars ; 73 92 97 Fachbereich Medizintechnik und Technomathematik OPUS4-3988 Wissenschaftlicher Artikel Kirchner, Patrick, kirchner@fh-aachen.de; Li, B., ; Spelthahn, H., ; Henkel, H., ; Friedrich, P., ; Kolstad, J., ; Keusgen, M., ; Schöning, Michael Josef, schoening@fh-aachen.de Thin-film calorimetric H2O2 gas sensor for the validation of germicidal effectivity in aseptic filling processes 2009 3 Procedia Chemistry. 1 (2009), H. 1 1876-6196 Proceedings of the Eurosensors XXIII conference ; Eurosensors 23 983 986 campus http://dx.doi.org/10.1016/j.proche.2009.07.245 Fachbereich Medizintechnik und Technomathematik OPUS4-4370 Wissenschaftlicher Artikel Kirchner, Patrick, kirchner@fh-aachen.de; Li, Bin, ; Spelthahn, Heiko, spelthahn@fh-aachen.de; Henkel, Hartmut, ; Schneider, Andreas, ; Friedrich, Peter, ; Kolstad, Jens, ; Keusgen, Michael, ; Schöning, Michael Josef, schoening@fh-aachen.de Thin-film calorimetric H2O2 gas sensor for the validation of germicidal effectivity in aseptic filling processes Amsterdam Elsevier 2011 6 Sensors and Actuators B: Chemical. 154 (2011), H. 2 1873-3077 EUROSENSORS XXIII 257 263 campus http://dx.doi.org/10.1016/j.snb.2010.01.058 Fachbereich Medizintechnik und Technomathematik OPUS4-6854 Konferenzveröffentlichung Yoshinobu, T., ; Schöning, Michael Josef, schoening@fh-aachen.de; Finger, F., ; Moritz, W., ; Iwasaki, H., Thin-film a-Si LAPS : Preparation and pH sensitivity 2003 1 Eurosensors XVII : the 17th European Conference on Solid-State Transducers ; University of Minho, Guimarães, Portugal, September 21 - 24, 2003 Eurosensors <17, 2003, Guimarães> 88 89 weltweit http://repositorium.sdum.uminho.pt/bitstream/1822/4837/1/BookOfAbstractsFinal.pdf Fachbereich Medizintechnik und Technomathematik OPUS4-1818 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Schmidt, C., ; Schubert, J., ; Zander, W., ; Mesters, S., ; Kordos, P., ; Lüth, H., ; Legin, A., ; Seleznev, B., ; Vlasov, Y. G., Thin film sensors on the basis of chalcogenide glass materials prepared by pulsed laser deposition technique 2000 5 Sensors and Actuators B. 68 (2000), H. 1-3 0925-4005 254 259 campus http://dx.doi.org/10.1016/S0925-4005(00)00438-X Fachbereich Medizintechnik und Technomathematik OPUS4-2019 Wissenschaftlicher Artikel Mourzina, Yu.G., ; Schöning, Michael Josef, schoening@fh-aachen.de; Schubert, J., ; Zander, W., ; Legin, A., ; Vlasov, Y. G., ; Lüth, H., Thin film microsensors for fast heavy metal analysis Lyngby, Denmark MIC, Mikroelektronik Centret 2000 1 CD-ROM Proceedings : Copenhagen, Denmark, 27 - 30 August 2000 / [ed.: R. de Reus ...] 87-89935-50-0 Eurosensors ; (14, 2000, København) ; Eurosensors ; (14 : ; 2000.08.27-30 : ; Copenhagen) ; European Conference on Solid-State Transducers ; (14 : ; 2000.08.27-30 : ; Copenhagen) 839 840 Fachbereich Medizintechnik und Technomathematik OPUS4-2013 Wissenschaftlicher Artikel Mourzina, Y. G., ; Legin, A., ; Vlasov, Y. G., ; Schöning, Michael Josef, schoening@fh-aachen.de; Schubert, J., ; Zander, W., ; Lüth, H., Thin film chemical sensors based on chalcogenide glasses for „electronic tongue" applications Wunstorf AMA Service 2001 4 Sensor 2001 : 10th international conference, May 8 - 10, 2001, Exhibition Centre Nuremberg, Germany ; proceedings Sensor-Kongress ; (10, 2001, Nürnberg) Sensor 2001 Conference ; (10 : ; 2001.05.08-10 : ; Nuremberg) 137 141 Fachbereich Medizintechnik und Technomathematik OPUS4-10235 Wissenschaftlicher Artikel Molinnus, Denise, Molinnus@fh-aachen.de; Janus, Kevin Alexander, janus@fh-aachen.de; Fang, Anyelina C., ; Drinic, Aleksander, ; Achtsnicht, Stefan, achtsnicht@fh-aachen.de; Köpf, Marius, ; Keusgen, Michael, ; Schöning, Michael Josef, schoening@fh-aachen.de Thick-film carbon electrode deposited onto a biodegradable fibroin substrate for biosensing applications This study addresses a proof-of-concept experiment with a biocompatible screen-printed carbon electrode deposited onto a biocompatible and biodegradable substrate, which is made of fibroin, a protein derived from silk of the Bombyx mori silkworm. To demonstrate the sensor performance, the carbon electrode is functionalized as a glucose biosensor with the enzyme glucose oxidase and encapsulated with a silicone rubber to ensure biocompatibility of the contact wires. The carbon electrode is fabricated by means of thick-film technology including a curing step to solidify the carbon paste. The influence of the curing temperature and curing time on the electrode morphology is analyzed via scanning electron microscopy. The electrochemical characterization of the glucose biosensor is performed by amperometric/voltammetric measurements of different glucose concentrations in phosphate buffer. Herein, systematic studies at applied potentials from 500 to 1200 mV to the carbon working electrode (vs the Ag/AgCl reference electrode) allow to determine the optimal working potential. Additionally, the influence of the curing parameters on the glucose sensitivity is examined over a time period of up to 361 days. The sensor shows a negligible cross-sensitivity toward ascorbic acid, noradrenaline, and adrenaline. The developed biocompatible biosensor is highly promising for future in vivo and epidermal applications. Weinheim Wiley-VCH 2022 8 Physica status solidi (a) 219 Corresponding author: Michael J. Schöning 23 1 9 10.1002/pssa.202200100 weltweit https://doi.org/10.1002/pssa.202200100 Fachbereich Medizintechnik und Technomathematik OPUS4-8373 Wissenschaftlicher Artikel Jildeh, Zaid B., ; Oberländer, Jan, oberlaender@fh-aachen.de; Kirchner, Patrick, kirchner@fh-aachen.de; Wagner, Patrick H., ; Schöning, Michael Josef, schoening@fh-aachen.de Thermocatalytic Behavior of Manganese (IV) Oxide as Nanoporous Material on the Dissociation of a Gas Mixture Containing Hydrogen Peroxide In this article, we present an overview on the thermocatalytic reaction of hydrogen peroxide (H₂O₂) gas on a manganese (IV) oxide (MnO₂) catalytic structure. The principle of operation and manufacturing techniques are introduced for a calorimetric H₂O₂ gas sensor based on porous MnO₂. Results from surface analyses by X-ray photoelectron spectroscopy (XPS) and scanning electron microscopy (SEM) of the catalytic material provide indication of the H₂O₂ dissociation reaction schemes. The correlation between theory and the experiments is documented in numerical models of the catalytic reaction. The aim of the numerical models is to provide further information on the reaction kinetics and performance enhancement of the porous MnO₂ catalyst. Basel MDPI 2018 Nanomaterials 8 4 262 10.3390/nano8040262 weltweit https://doi.org/10.3390/nano8040262 Fachbereich Medizintechnik und Technomathematik OPUS4-6417 Wissenschaftlicher Artikel Guo, Yuanyuan, ; Miyamoto, Ko-ichiro, ; Wagner, Torsten, torsten.wagner@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de; Yoshinobu, Tatsuo, Theoretical study and simulation of light-addressable potentiometric sensors The light-addressable potentiometric sensor (LAPS) is a semiconductor-based potentiometric sensor using a light probe with an ability of detecting the concentration of biochemical species in a spatially resolved manner. As an important biomedical sensor, research has been conducted to improve its performance, for instance, to realize high-speed measurement. In this work, the idea of facilitating the device-level simulation, instead of using an equivalent-circuit model, is presented for detailed analysis and optimization of the performance of the LAPS. Both carrier distribution and photocurrent response have been simulated to provide new insight into both amplitude-mode and phase-mode operations of the LAPS. Various device parameters can be examined to effectively design and optimize the LAPS structures and setups for enhanced performance. Weinheim Wiley-VCH 2014 5 Physica status solidi (A) : applications and materials 211 6 1467 1472 10.1002/pssa.201330354 campus https://doi.org/10.1002/pssa.201330354 Fachbereich Chemie und Biotechnologie OPUS4-1714 Wissenschaftlicher Artikel Schöning, Michael Josef, schoening@fh-aachen.de; Schroth, P., ; Schütz, S., The use of insect chemoreceptors for the assembly of biosensors based on semiconductor field-effect sensors 2000 7 Electroanalysis. 12 (2000), H. 9 1040-0397 645 652 campus http://www3.interscience.wiley.com/cgi-bin/fulltext/72507591/PDFSTART Fachbereich Medizintechnik und Technomathematik OPUS4-5986 Wissenschaftlicher Artikel Voigt, Birgit, ; Schroeter, Rebecca, ; Jürgen, Britta, ; Albrecht, Dirk, ; Evers, Stefan, ; Bongaerts, Johannes, bongaerts@fh-aachen.de; Maurer, Karl-Heinz, ; Schweder, Thomas, ; Hecker, Michael, The response of Bacillus licheniformis to heat and ethanol stress and the role of the SigB regulon Weinheim Wiley 2013 6 Proteomics Vol. 13 Iss. 14 2140 2146 campus http://dx.doi.org/10.1002/pmic.201200297 Fachbereich Chemie und Biotechnologie OPUS4-1954 Wissenschaftlicher Artikel Yoshinobu, T., ; Iwasaki, H., ; Ui, Y., ; Furuichi, K., ; Ermelenko, Y., ; Mourzina, Y., ; Wagner, Torsten, torsten.wagner@fh-aachen.de; Näther, Niko, naether@fh-aachen.de; Schöning, Michael Josef, schoening@fh-aachen.de The light-addressable potentiometric sensor for multi-ion sensing and imaging 2005 3 Methods. 37 (2005), H. 1 1046-2023 99 102 campus http://dx.doi.org/10.1016/j.ymeth.2005.05.020 Fachbereich Medizintechnik und Technomathematik