TY  - JOUR
A1  - Digel, Ilya
T1  - Primary thermosensory events in cells
JF  - Transient receptor potential channels / Md. Shahidul Islam, ed.
Y1  - 2011
SN  - 978-94-007-0264-6
N1  - (Advances in experimental medicine and biology ; 704)
SP  - 451
EP  - 468
PB  - Springer
CY  - Dordrecht [u.a.]
ER  - 
TY  - JOUR
A1  - Digel, Ilya
T1  - Controlling microbial adhesion : a surface engineering approach
JF  - Bioengineering in Cell and Tissue Research / Artmann, Gerhard M. ; Chien, Shu (Eds.)
Y1  - 2008
SN  - 978-3-540-75408-4
SP  - 601
EP  - 625
PB  - Springer
CY  - Berlin [u.a.]
ER  - 
TY  - JOUR
A1  - Digel, Ilya
A1  - Kurulgan Demirci, Eylem
A1  - Linder, Peter
A1  - Kayser, Peter
T1  - Decrease in extracellular collagen crosslinking after NMR magnetic field application in skin fibroblasts
JF  - Medical and Biological Engineering and Computing. 45 (2007), H. 1
Y1  - 2007
SN  - 1741-0444
SP  - 91
EP  - 97
ER  - 
TY  - JOUR
A1  - Digel, Ilya
A1  - Maggakis-Kelemen, Christina
A1  - Zerlin, Kay
A1  - Linder, Peter
T1  - Body temperature-related structural transitions of monotremal and human hemoglobin
JF  - Biophysical Journal. 91 (2006), H. 8
Y1  - 2006
SN  - 1542-0086
SP  - 3014
EP  - 3021
ER  - 
TY  - JOUR
A1  - Bogoyavlenskiy, A. P.
A1  - Berezin, V. E.
A1  - Ogneva, A. V.
A1  - Tolmacheva, V. P.
A1  - Digel, Ilya
A1  - Khudyakova, S. S.
T1  - Immunostimulating activity of a saponin-containing extract of Saponaria officinalis
JF  - Voprosy virusologii
Y1  - 1999
SN  - 0507-4088
VL  - 44
IS  - 5
SP  - 229
EP  - 232
ER  - 
TY  - JOUR
A1  - Mansurov, Z. A.
A1  - Jandosov, J. M.
A1  - Kerimkulova, A. R.
A1  - Azat, S.
A1  - Zhubanova, A. A.
A1  - Digel, Ilya
A1  - Savistkaya, I. S.
A1  - Akimbekov, N. S.
A1  - Kistaubaeva, A. S.
T1  - Nanostructured carbon materials for biomedical use
JF  - Eurasian chemico-technological journal : quarterly journal of the International Higher Education Academy of Sciences
N2  - One of the priority trends of carbon nanotechnology is creation of nanocomposite systems. Such carbon nanostructured composites were produced using - raw materials based on the products of agricultural waste, such as grape stones, apricot stones, rice husk. These products have a - wide spectrum of application and can be obtained in large quantities. The Institute of Combustion Problems has carried out the work on synthesis of the nanostructured carbon sorbents for multiple applications including the field of biomedicine. The article presents the data on the synthesis and physico-chemical properties of carbonaceous sorbents using physicochemical methods of investigation: separation and purification of biomolecules; isolation of phytohormone - fusicoccin; adsorbent INGO-1 in the form of an adsorption column for blood detoxification, oral (entero) sorbent - INGO-2; the study of efferent and probiotic properties and sorption activity in regard to the lipopolysaccharide (LPS), new biocomposites - based on carbonized rice husk (CRH) and cellular microorganisms; the use of CRH in wound treatment. A new material for blood detoxication (INGO-1) has been obtained. Adsorption of p-cresyl sulfate and indoxyl sulfate has shown that active carbon adsorbent can remove clinically significant level of p-cresyl sulfate and indoxyl sulfate from human plasma. Enterosorbent INGO-2 possesses high adsorption activity in relation to Gram-negative bacteria and their endotoxins. INGO-2 slows down the growth of conditionally pathogenic microorganisms, without having a negative effect on bifido and lactobacteria. The use of enterosorbent INGO-2 for sorption therapy may provide a solution to a complex problem - detoxication of the digestive tract and normalization of the intestinal micro ecology. The immobilized probiotic called "Riso-lact" was registered at the Ministry of Health of the Republic of Kazakhstan as a biologically active food additive. The developed technology is patented and provides production of the medicine in the form of freeze-dried biomass immobilized in vials.
Y1  - 2014
U6  - http://dx.doi.org/10.18321/ectj224
SN  - 1562-3920
VL  - 15 (2013)
IS  - 3
SP  - 209
EP  - 217
PB  - Institute of Combustion Problems
CY  - Almaty
ER  - 
TY  - JOUR
A1  - Turaliyeva, M.
A1  - Yeshibaev, A.
A1  - Digel, Ilya
A1  - Elibayeva, G.
A1  - Sydykova, A.
A1  - Uspabayeva, A.
A1  - Dosybayeva, G.
A1  - Zhylysbayeva, A.
A1  - Lakhanova, K.
T1  - Molecular-genetic identification of emerged novel invasive pathogens of Asiatic Elm Ulmus pumila L
JF  - Life science journal
N2  - The dwarf elm Ulmus pumila L. (Ulmaceae) is one of indigenous species of flora in Kazakhstan and forms a basis of dendroflora in virtually all settlements of the region. In the past decade, multiple outbreaks of previously unknown diseases of the small-leaved elm have been registered. In our study, by the molecular-genetic analysis it was found that the pathogens responsible for the outbreaks are microfungi belonging to the genus Fusarium – F. solani and F. oxysporum. The nucleotide sequences (ITS regions) isolated from the diseased trees showed very high similarity with the GenBank control numbers EU625403.1 and FJ478128.1 (100.0 and 99.0 % respectively). Oncoming research will focus on the search of natural microbial antagonists of the discovered phytopathogens.
Y1  - 2014
U6  - http://dx.doi.org/10.7537/marslsj1105s14.33
SN  - 1097-8135
VL  - 11
IS  - Spec. iss. 5s
SP  - 171
EP  - 175
PB  - Marsland Press
CY  - New York
ER  - 
TY  - JOUR
A1  - Savitskaya, I.S.
A1  - Kistaubayeva, A.S.
A1  - Ignatova, L.V.
A1  - Digel, Ilya
T1  - Antimicrobial and wound healing properties of a bacterial cellulose based material containing B. subtilis cells
JF  - Heliyon
Y1  - 2019
U6  - http://dx.doi.org/10.1016/j.heliyon.2019.e02592
SN  - 2405-8440
VL  - 5
IS  - 10
SP  - Artikelnummer e02592
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Akimbekov, N. S.
A1  - Digel, Ilya
A1  - Tastambek, K. T.
A1  - Zhubanova, A. A.
T1  - Biocompatibility of carbonized rice husk with a rat heart cells line H9c2
JF  - Experimental Biology
Y1  - 2013
SN  - 1563-0218
N1  - Original in russischer Sprache
VL  - 59
IS  - 3/1
SP  - 23
EP  - 25
ER  - 
TY  - JOUR
A1  - Akimbekov, N.Sh.
A1  - Digel, Ilya
A1  - Savitkaya, I.S.
A1  - Zhubanova, A.A.
A1  - Tastambek, K.T.
T1  - Investigations of LPS endotoxin elimination in the flowing column conditions with the sorbent on the basis of carbonized rice husk
JF  - KazNU Bulletin. Biology series
Y1  - 2013
SN  - 1563-0218
N1  - Original in russischer Sprache
VL  - 57
IS  - 1
SP  - 124
EP  - 127
ER  - 
TY  - JOUR
A1  - Aimenova, Zh. E.
A1  - Digel, Ilya
A1  - Eshibaev, А. А.
T1  - Dynamics of accumulation of lagochirzin in Lagochilus setulosus phytomass during the growing season and also features of its cultivation in the conditions of a typical sierozem
JF  - KazNU Bulletin. Biology series
N2  - L.setulosus is offered for creation of biopreparation «Setulin», possesing he- mostatic action, the basic reactant of biopreparation is diterpen – lagochirzin. Results under the maintenance and dynamics of diterpen lagochirzin accumula- tion in various parts of L.setulosus are presented: in roots, stalks, leaves, flowers and calyx lobes during the growing season, and also results on conditions of cultivation L.setulosus in the conditions of a typical sierozem are resulted. From the obtained data is visible, that the given species of a plant is endemic. It is established, that dynamics of accumulation of lagochirzin in phytomass accrues from the beginning to the middle of the growing season. The chemical analysis of L.setulosus on a localization of lagochirzin in various organs of a plant, has shown, that the greatest quantity of lagochirzin collects in calyx lobes of the  plants. Also it is established, that L.setulosus can be cultivated in the conditions of the typical sierozem, a mineral food is necessary for the given species of plants of Lagochilus genus, except nitric fertilizers. Comparative studying of wild-growing and cultural forms of L.setulosus has shown, that in the cultivated phytomass of plants the maintenance of lagochirzin on 17-20 % higher than in the wild-growing species.
Y1  - 2016
SN  - 1563-0218
N1  - Original in russischer Sprache
VL  - 69
IS  - 4
SP  - 4
EP  - 11
PB  - Al-Farabi Kazakh National University
CY  - Almaty
ER  - 
TY  - JOUR
A1  - Digel, Ilya
A1  - Wehlitz, V.
A1  - Kayser, Peter
A1  - Figiel-Lange, A.
A1  - Bassam, R.
A1  - Rundstedt, F. von
T1  - Suspension depletion approach for exemption of infected Solanum jasminoides cells from pospiviroids
JF  - Plant Pathology
N2  - Despite numerous studies, viroid elimination from infected plants remains a very challenging task. This study introduces for the first time a novel ‘suspension depletion’ approach for exemption of Solanum jasminoides plants from viroids. The proposed method implies initial establishment of suspension cultures of the infected plant cells. The suspended cells were then physically treated (mild thermotherapy, 33 °C), which presumably delayed the replication of the viroid. The viroid concentration in the treated biomass was monitored weekly using pospiviroid-specific PCR. After 10–12 weeks of continuous treatment, a sufficient decrease in viroid concentration was observed such that the infection became undetectable by PCR. The treated single cells then gave rise to microcolonies on a solid culture medium and the obtained viroid-negative clones were further promoted to regenerate into viroid-free plants. Three years of accumulated experimental data suggests feasibility, broad applicability, and good efficacy of the proposed approach.
Y1  - 2018
U6  - http://dx.doi.org/10.1111/ppa.12750
SN  - 1365-3059
VL  - 67
IS  - 2
SP  - 358
EP  - 365
PB  - Wiley
CY  - Oxford
ER  - 
TY  - JOUR
A1  - Mansurov, Z.
A1  - Digel, Ilya
A1  - Biisenbaev, M.
A1  - Savistkaya, I.
A1  - Kistaubaeva, A.
A1  - Akimbekov, N.
A1  - Zhubanova, A.
T1  - Bio-composite material on the basis of carbonized rice husk in biomedicine and environmental applications
JF  - Eurasian Chemico-Technological Journal
Y1  - 2012
U6  - http://dx.doi.org/10.18321/ectj105
SN  - 2522-4867
VL  - 14
IS  - 2
SP  - 115
EP  - 131
PB  - Institute of Combustion Problems
CY  - Almaty
ER  - 
TY  - JOUR
A1  - Savitskaya, I. S.
A1  - Kistaubayeva, A. S.
A1  - Digel, Ilya
A1  - Shokatayeva, D. H.
T1  - Physicochemical and Antibacterial Properties of Composite Films Based on Bacterial Cellulose and Chitosan for Wound Dressing Materials
JF  - Eurasian Chemico-Technological Journal
Y1  - 2017
U6  - http://dx.doi.org/10.18321/ectj670
SN  - 2522-4867
VL  - 19
IS  - 3
SP  - 255
EP  - 264
ER  - 
TY  - JOUR
A1  - Akimbekov, N. Sh.
A1  - Digel, Ilya
A1  - Zhubanova, A. A.
T1  - Advantages of creation of e-books in training of specialists biologists and biotechnologists
JF  - KazNU Bulletin. Biology series.
N2  - The necessity of e-books as a primary of learning, its opportunities for realization of competence during training biologist and biotechnologist specialists are determined. Definitions and requirements to the e-books, its advantages in comparison with traditional textbooks, and the ways of creation of e-books in the SunRav BookEditor program are considered.
KW  - SunRav BookEditor
KW  - softs
KW  - distance learning
KW  - e-issues
KW  - e-books
Y1  - 2014
SN  - 1563-0218
VL  - 60
IS  - 1
SP  - 249
EP  - 252
PB  - Al-Farabi Kazakh National University
CY  - Almaty
ER  - 
TY  - JOUR
A1  - Sagymbay, Altynay
A1  - G.E., Nusupbaeva
A1  - N.Zh, Tleumbetova
A1  - A.S., Mutalieva
A1  - Nurpeisova, Ainur
A1  - D.B., Jussupova
A1  - Digel, Ilya
T1  - Molecular genetics features of the epidemic season 2017-2018 on the influenza in Kazakhstan
JF  - Eurasian Journal of  Ecology
Y1  - 2019
SN  - 2617-7358
VL  - 58
IS  - 1
SP  - 50
EP  - 60
ER  - 
TY  - JOUR
A1  - Zhubanova, А.
A1  - Mansurov, Z.A.
A1  - Digel, Ilya
A1  - Saviskaya, I.S.
A1  - Akimbekov, N.Sh.
T1  - Designing of Heterogeneous Nanobiocomposites for Biotechnology
JF  - KazNU Bulletin. Biology series
Y1  - 2013
SN  - 1563-0218
VL  - 59
IS  - No 3/1
SP  - 89
EP  - 93
ER  - 
TY  - JOUR
A1  - Akimbekov, N.Sh.
A1  - Digel, Ilya
A1  - O’Heras, C.
A1  - Tastambek, K.T.
A1  - Savitskaya, I.S.
A1  - Ualyeva, P.S.
A1  - Mansurov, Z.A.
A1  - Zhubanova, A.A.
T1  - Adsorption of bacterial lipopol ysaccharides on carbonized ri ce husks obtained in the batch  experiments
JF  - KazNU Bulletin. Biology series
Y1  - 2015
SN  - 1563-0218
VL  - 60
IS  - No 1/2
SP  - 144
EP  - 148
ER  - 
TY  - JOUR
A1  - Akimbekov, N.Sh.
A1  - Digel, Ilya
A1  - O´Heras, C.
A1  - Tastambek, K.T.
A1  - Savitskaya, I.S.
A1  - Ualyeva, P.S.
A1  - Mansurov, Z.A.
A1  - Zhubanova, A.A.
T1  - Adsorption of bacterial lipopolysaccharides on carbonized rice husks obtained in the batch experiments
JF  - Experimental Biology
N2  - The  scope  of  this  study  is  the  measurement  of  endotoxin  adsorption  rate  for  carbonized  rice  husk.  It  showed  good  adsorption properties for LPS. During the batch experiments, several techniques were used and optimized for improving the  material’s  adsorption  behavior.  Also,  with  the  results  obtained  it  was  possible  to  differentiate  the  materials  according to their adsorption capacity and kinetic characteristics.
KW  - surface modification
KW  - adsorption
KW  - carbonized rice husk
KW  - lipopolysaccharide
Y1  - 2014
SN  - 1563-0218
N1  - Original in russischer Sprache
VL  - 60
IS  - 1/2
SP  - 144
EP  - 148
PB  - Al-Farabi Kazakh National University
CY  - Almaty
ER  - 
TY  - JOUR
A1  - Akimbekov, N. Sh.
A1  - Digel, Ilya
A1  - Zhubanova, A. A.
T1  - Investigation the Influence of Carbonized Material Based On Rice Husk on Viability and Migration of Fibroblasts in T3B3 Cell Culture
JF  - KazNU Bulletin. Biology series
Y1  - 2013
SN  - 1563-0218
N1  - Original in russischer Sprache
VL  - 59
IS  - 3/1
SP  - 20
EP  - 23
ER  -