TY  - JOUR
A1  - Artmann, Gerhard
A1  - Kelemen, C.
A1  - Chien, S.
T1  - Temperature transition of human hemoglobin at body temperature: effects of calcium. Kelemen, C.; Chien, S.; Artmann, Gerhard Michael
JF  - Biophysical journal. 80 (2001), H. 6
Y1  - 2001
SN  - 1542-0086
SP  - 2622
EP  - 2630
ER  - 
TY  - JOUR
A1  - Artmann, Gerhard
A1  - Kelemen, Christina
A1  - Porst, Dariusz
A1  - Büldt, G. [u.a.]
T1  - Temperature transitions of protein properties in human red blood cells. Artmann, Gerhard Michael, Kelemen, Christina; Porst, D.; Büldt, G.; Chien, S.
JF  - Biophysical Journal. 75 (1998), H. 6
Y1  - 1998
SN  - 1542-0086
N1  - http://www.pubmedcentral.nih.gov/picrender.fcgi?artid=1299989&blobtype=pdf
SP  - 3179
EP  - 3183
ER  - 
TY  - JOUR
A1  - Heinke, Lars N.
A1  - Knicker, Axel J.
A1  - Albracht, Kirsten
T1  - Test-retest reliability of the internal shoulder rotator muscles' stretch reflex in healthy men
JF  - Journal of Electromyography and Kinesiology
N2  - Until now the reproducibility of the short latency stretch reflex of the internal rotator muscles of the glenohumeral joint has not been identified. Twenty-three healthy male participants performed three sets of external shoulder rotation stretches with various pre-activation levels on two different dates of measurement to assess test-retest reliability. All stretches were applied with a dynamometer acceleration of 104°/s2 and a velocity of 150°/s. Electromyographical response was measured via surface EMG. Reflex latencies showed a pre-activation effect (ƞ2 = 0,355). ICC ranged from 0,735 to 0,909 indicating an overall “good” relative reliability. SRD 95% lay between ±7,0 to ±12,3 ms.. The reflex gain showed overall poor test-retest reproducibility. The chosen methodological approach presented a suitable test protocol for shoulder muscles stretch reflex latency evaluation. A proof-of-concept study to validate the presented methodical approach in shoulder involvement including subjects with clinically relevant conditions is recommended.
KW  - stretch reflex
KW  - shoulder
KW  - test-retest reliability
KW  - intraclass correlation coefficient
KW  - standard error of measurement
Y1  - 2021
U6  - http://dx.doi.org/10.1016/j.jelekin.2021.102611
SN  - 1050-6411
VL  - 62
IS  - Article 102611
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Waldvogel, Janice
A1  - Ritzmann, Ramona
A1  - Freyler, Kathrin
A1  - Helm, Michael
A1  - Monti, Elena
A1  - Albracht, Kirsten
A1  - Stäudle, Benjamin
A1  - Gollhofer, Albert
A1  - Narici, Marco
T1  - The Anticipation of Gravity in Human Ballistic Movement
JF  - Frontiers in Physiology
N2  - Stretch-shortening type actions are characterized by lengthening of the pre-activated muscle-tendon unit (MTU) in the eccentric phase immediately followed by muscle shortening. Under 1 g, pre-activity before and muscle activity after ground contact, scale muscle stiffness, which is crucial for the recoil properties of the MTU in the subsequent push-off. This study aimed to examine the neuro-mechanical coupling of the stretch-shortening cycle in response to gravity levels ranging from 0.1 to 2 g. During parabolic flights, 17 subjects performed drop jumps while electromyography (EMG) of the lower limb muscles was combined with ultrasound images of the gastrocnemius medialis, 2D kinematics and kinetics to depict changes in energy management and performance. Neuro-mechanical coupling in 1 g was characterized by high magnitudes of pre-activity and eccentric muscle activity allowing an isometric muscle behavior during ground contact. EMG during pre-activity and the concentric phase systematically increased from 0.1 to 1 g. Below 1 g the EMG in the eccentric phase was diminished, leading to muscle lengthening and reduced MTU stretches. Kinetic energy at take-off and performance were decreased compared to 1 g. Above 1 g, reduced EMG in the eccentric phase was accompanied by large MTU and muscle stretch, increased joint flexion amplitudes, energy loss and reduced performance. The energy outcome function established by linear mixed model reveals that the central nervous system regulates the extensor muscles phase- and load-specifically. In conclusion, neuro-mechanical coupling appears to be optimized in 1 g. Below 1 g, the energy outcome is compromised by reduced muscle stiffness. Above 1 g, loading progressively induces muscle lengthening, thus facilitating energy dissipation.
Y1  - 2021
U6  - http://dx.doi.org/10.3389/fphys.2021.614060
SN  - 1664-042X
PB  - Frontiers
CY  - Lausanne
ER  - 
TY  - JOUR
A1  - Temiz Artmann, Aysegül
A1  - Saklamaz, Ali
A1  - Comlekci, Abdurrahman
A1  - Caliskan, Sezer
T1  - The beneficial effects of lipid-lowering drugs beyond lipid-lowering effects: A comparative study with pravastatin, atorvastatin, and fenofibrate in patients with type IIa and type IIb hyperlipidemia / Saklamaz, Ali ; Comlekci, Abdurrahman ; Temiz, Aysegu
JF  - Metabolism. 54 (2005), H. 5
Y1  - 2005
SN  - 0026-0495
SP  - 677
EP  - 681
ER  - 
TY  - JOUR
A1  - Attar, Mandana Hossein Zadeh
A1  - Merk, Hans F.
A1  - Kotliar, Konstantin
A1  - Wurpts, Gerda
A1  - Röseler, Stefani
A1  - Moll-Slodowy, Silke
A1  - Plange, Johann
A1  - Baron, Jens Malte
A1  - Balakirski, Galina
T1  - The CD63 basophil activation test as a diagnostic tool for assessing autoimmunity in patients with chronic spontaneous urticaria
JF  - European Journal of Dermatology
Y1  - 2019
U6  - http://dx.doi.org/10.1684/ejd.2019.3680
VL  - 29
IS  - 6
SP  - 614
EP  - 618
ER  - 
TY  - JOUR
A1  - Akimbekov, Nuraly
A1  - Qiao, Xiaohui
A1  - Digel, Ilya
A1  - Abdieva, Gulzhamal
A1  - Ualieva, Perizat
A1  - Zhubanova, Azhar
T1  - The effect of leonardite-derived amendments on soil microbiome structure and potato yield
JF  - Agriculture
N2  - Humic substances originating from various organic matters can ameliorate soil properties, stimulate plant growth, and improve nutrient uptake. Due to the low calorific heating value, leonardite is rather unsuitable as fuel. However, it may serve as a potential source of humic substances. This study was aimed at characterizing the leonardite-based soil amendments and examining the effect of their application on the soil microbial community, as well as on potato growth and tuber yield. A high yield (71.1%) of humic acid (LHA) from leonardite has been demonstrated. Parental leonardite (PL) and LHA were applied to soil prior to potato cultivation. The 16S rRNA sequencing of soil samples revealed distinct relationships between microbial community composition and the application of leonardite-based soil amendments. Potato tubers were planted in pots in greenhouse conditions. The tubers were harvested at the mature stage for the determination of growth and yield parameters. The results demonstrated that the LHA treatments had a significant effect on increasing potato growth (54.9%) and tuber yield (66.4%) when compared to the control. The findings highlight the importance of amending leonardite-based humic products for maintaining the biogeochemical stability of soils, for keeping their healthy microbial community structure, and for increasing the agronomic productivity of potato plants.
Y1  - 2020
U6  - http://dx.doi.org/10.3390/agriculture10050147
VL  - 10
IS  - Art. 147
SP  - 1
EP  - 17
PB  - MDPI
CY  - Basel
ER  - 
TY  - JOUR
A1  - Temiz Artmann, Aysegül
A1  - Yolcuoglu, B.
A1  - Onal, M. A.
A1  - Sipahi, O.
T1  - The effect of skin transplantation on tumour growth in mice. Yolcuoglu, B.; Onal, M. A.; Sipahi, O.; Temiz, A.; Pekcetin, C.; Acikgöz, O.; Kar,  H.; Güre A.
JF  - The American Journal of Surgery. 178 (1999), H. 4
Y1  - 1999
SN  - 0002-9610
SP  - 329
EP  - 330
ER  - 
TY  - JOUR
A1  - Temiz Artmann, Aysegül
A1  - Cavdar, C.
A1  - Yenicerioglu, Y.
A1  - Caliskan, S.
T1  - The effects of intravenous iron treatment on oxidant stress and erythrocyte deformability in haemodialysis patients. Cavdar, C.; Temiz, A.; Yenicerioglu, Y.; Caliskan, S.; Celik, A.; Sifil, A.; Onvural, B.; Camsari, T.
JF  - Scandinavian Journal of Urology and Nephrology. 37 (2003), H. 1
Y1  - 2003
SN  - 0036-5599
SP  - 77
EP  - 82
ER  - 
TY  - JOUR
A1  - Digel, Ilya
A1  - Temiz Artmann, Aysegül
T1  - The emperor's new body : seeking for a blueprint of limb regeneration in humans
JF  - Stem cell engineering : principles and applications / Gerhard M. Artmann ... eds.
Y1  - 2011
SN  - 978-3-642-11864-7
SP  - 3
EP  - 37
PB  - Springer
CY  - Berlin [u.a.]
ER  - 
TY  - JOUR
A1  - Lyons, W. Berry
A1  - Mikucki, Jill A.
A1  - German, Laura A.
A1  - Welch, Kathleen A.
A1  - Welch, Susan A.
A1  - Gardener, Christopher B.
A1  - Tulaczyk, Slawek M.
A1  - Pettit, Erin C.
A1  - Kowalski, Julia
A1  - Dachwald, Bernd
T1  - The Geochemistry of Englacial Brine from Taylor Glacier, Antarctica
JF  - Journal of Geophysical Research: Biogeosciences
Y1  - 2019
U6  - http://dx.doi.org/10.1029/2018JG004411
SN  - 2169-8961
PB  - Wiley
CY  - Hoboken
ER  - 
TY  - JOUR
A1  - Behbahani, Mehdi
A1  - Probst, M.
A1  - Mai, A.
A1  - Tran, L.
A1  - Vonderstein, K.
A1  - Keschenau, P.
A1  - Linde, T.
A1  - Steinseifer, U.
A1  - Behr, M.
A1  - Mottaghy, K.
T1  - The influence of high shear on thrombosis and hemolysis in artificial organs
JF  - Artificial Organs
Y1  - 2010
SN  - 0391-3988
N1  - Special Issue: SI ; Meeting abstract
VL  - 33
IS  - 7
SP  - 426
EP  - 426
ER  - 
TY  - JOUR
A1  - Artmann, Gerhard
A1  - Schmid-Schönbein, H.
T1  - The microscope-photometrical-monolayer-technique- a new principle for analyzing the distribution of rheological responses in pathological and experimentally modified red cell populations. Artmann, Gerhard Michael; Schmid-Schönbein, H.
JF  - Microcirculation, an update : proceedings of the Fourth World Congress for Microcirculation, Tokyo, Japan, July 26-30, 1987
Y1  - 1987
SN  - 0444809511
N1  - World Congress for Microcirculation (4, 1987, Tokyo;); International congress series ; 755
SP  - 475
EP  - 477
PB  - Excerpta Medica
CY  - Amsterdam [u.a.]
ER  - 
TY  - JOUR
A1  - Zhubanova, Azhar A.
A1  - Digel, Ilya
A1  - Nojima, H.
A1  - Artmann, Gerhard
T1  - The use of bactericidal effects of cluster ions generated by plasma in medical biotechnology
N2  - The most of conventional methods of air purification use the power of a fan to draw in air and pass it through a filter. The problem of bacterial contamination of inner parts of such a type of air conditioners in some cases draws attention towards alternative air-cleaning systems. Some manufacturers offer to use the ozone's bactericidal and deodorizing effects, but the wide spreading of such systems is restricted by the fact that toxic effects of ozone in respect of human beings are well known. In 2000 Sharp Inc. introduced "Plasma Cluster Ions (PCI)" air purification technology, which uses plasma discharge to generate cluster ions (I 0-14 ). This technology has been developed for those customers that are conscious about health and hygiene. In our experiments, we focused on some principal aspects of plasma-generated ions application - time-dependency and irreversibility of bactericidal action, spatial and kinetic characteristics of emitted cluster particles, their chemical targets in the microbial cells.
KW  - Clusterion
KW  - Raumluft
KW  - Luftreiniger
KW  - Plasmacluster ion technology
KW  - Air purification
Y1  - 2007
ER  - 
TY  - JOUR
A1  - Digel, Ilya
A1  - Zhubanova, Azhar A.
A1  - Nojima, H.
A1  - Artmann, Gerhard
T1  - The use of bactericidal effects of cluster ions generated by plasma in medical biotechnology
JF  - Biotechnologija : teorija i praktika (2004)
Y1  - 2004
SN  - 1028-9399
SP  - 46
EP  - 52
ER  - 
TY  - JOUR
A1  - Ciobanu, Octavian
A1  - Staat, Manfred
A1  - Rahimi, Alireza
T1  - The use of open source software in biomechanical finite element analysis
JF  - Buletinul Institutului Politehnic din Iaşi / Universitatea Tehnică Gh. Asachi, Iaşi Secţia 5, Construcţii de maşini = Machine construction = Bulletin of the Polytechnic Institute of Jassy = Izvestija Jasskogo Politechničeskogo Instituta
Y1  - 2008
SN  - 1011-2855
VL  - 54
IS  - 7/8
SP  - 213
EP  - 220
ER  - 
TY  - JOUR
A1  - Stadler, Andreas M.
A1  - Garvey, G. J.
A1  - Bocahut, A.
A1  - Sacquin-Mora, S.
A1  - Digel, Ilya
A1  - Schneider, G. J.
A1  - Natali, F.
A1  - Artmann, Gerhard
A1  - Zaccai, G.
T1  - Thermal fluctuations of haemoglobin from different species : adaptation to temperature via conformational dynamics
JF  - Journal of the Royal Society Interface
N2  - Thermodynamic stability, configurational motions and internal forces of haemoglobin (Hb) of three endotherms (platypus, Ornithorhynchus anatinus; domestic chicken, Gallus gallus domesticus and human, Homo sapiens) and an ectotherm (salt water crocodile, Crocodylus porosus) were investigated using circular dichroism, incoherent elastic neutron scattering and coarse-grained Brownian dynamics simulations. The experimental results from Hb solutions revealed a direct correlation between protein resilience, melting temperature and average body temperature of the different species on the 0.1 ns time scale. Molecular forces appeared to be adapted to permit conformational fluctuations with a root mean square displacement close to 1.2 Å at the corresponding average body temperature of the endotherms. Strong forces within crocodile Hb maintain the amplitudes of motion within a narrow limit over the entire temperature range in which the animal lives. In fully hydrated powder samples of human and chicken, Hb mean square displacements and effective force constants on the 1 ns time scale showed no differences over the whole temperature range from 10 to 300 K, in contrast to the solution case. A complementary result of the study, therefore, is that one hydration layer is not sufficient to activate all conformational fluctuations of Hb in the pico- to nanosecond time scale which might be relevant for biological function. Coarse-grained Brownian dynamics simulations permitted to explore residue-specific effects. They indicated that temperature sensing of human and chicken Hb occurs mainly at residues lining internal cavities in the β-subunits.
Y1  - 2012
U6  - http://dx.doi.org/10.1098/rsif.2012.0364
SN  - 1742-5689
VL  - 9
IS  - 76
SP  - 2845
EP  - 2855
PB  - The Royal Society
CY  - London
ER  - 
TY  - JOUR
A1  - Behbahani, Mehdi
A1  - Behr, Marek
A1  - Nicolai, Mike
A1  - Probst, Markus
T1  - Towards Shape Optimization for Ventricular Assist Devices Using Parallel Stabilized FEM
JF  - NIC Symposium 2008 : symposium, 20 - 21 February 2008, Forschungszentrum Jülich ; proceedings / organized by John von Neumann Institute for Computing. Ed. by Gernot Münster; Dietrich Wolf; Manfred Kremer (ed.)
Y1  - 2008
SN  - 978-3-9810843-5-1
N1  - NIC series ; 39
SP  - 325
EP  - 332
PB  - Forschungszentrum
CY  - Jülich
ER  - 
TY  - JOUR
A1  - Staat, Manfred
A1  - Heitzer, M.
T1  - Traglastanalyse - ein strukturmechanisches Verfahren zur Beurteilung von gerissenen Bauteilen und Verbindungen
JF  - Festigkeits- und Bruchverhalten von Fügeverbindungen : 32. Tagung des DVM-Arbeitskreises Bruchvorgänge ; 22. und 23. Februar 2000 in Berlin / Richard, H. A. [Hrsg]
Y1  - 2000
N1  - DVM-Bericht 232
SP  - 183
EP  - 192
PB  - Deutscher Verband für Materialforschung und -prüfung
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Werkhausen, Amelie
A1  - Cronin, Neil J.
A1  - Albracht, Kirsten
A1  - Paulsen, Gøran
A1  - Larsen, Askild V.
A1  - Bojsen-Møller, Jens
A1  - Seynnes, Olivier R.
T1  - Training-induced increase in Achilles tendon stiffness affects tendon strain pattern during running
JF  - PeerJ
N2  - Background
During the stance phase of running, the elasticity of the Achilles tendon enables the utilisation of elastic energy and allows beneficial contractile conditions for the triceps surae muscles. However, the effect of changes in tendon mechanical properties induced by chronic loading is still poorly understood. We tested the hypothesis that a training-induced increase in Achilles tendon stiffness would result in reduced tendon strain during the stance phase of running, which would reduce fascicle strains in the triceps surae muscles, particularly in the mono-articular soleus.
Methods 
Eleven subjects were assigned to a training group performing isometric singleleg plantarflexion contractions three times per week for ten weeks, and another ten subjects formed a control group. Before and after the training period, Achilles tendon stiffness was estimated, and muscle-tendon mechanics were assessed during running at preferred speed using ultrasonography, kinematics and kinetics.
Results 
Achilles tendon stiffness increased by 18% (P <0:01) in the training group, but the associated reduction in strain seen during isometric contractions was not statistically significant. Tendon elongation during the stance phase of running was similar after training, but tendon recoil was reduced by 30% (P <0:01), while estimated tendon force remained unchanged. Neither gastrocnemius medialis nor soleus fascicle shortening during stance was affected by training.
Discussion 
These results show that a training-induced increase in Achilles tendon
stiffness altered tendon behaviour during running. Despite training-induced changes in tendon mechanical properties and recoil behaviour, the data suggest that fascicle shortening patterns were preserved for the running speed that we examined. The asymmetrical changes in tendon strain patterns supports the notion that simple inseries models do not fully explain the mechanical output of the muscle-tendon unit during a complex task like running.
KW  - Achilles tendon
KW  - Stiffness
KW  - Running
KW  - Tendon properties
KW  - Architectural gear ratio
Y1  - 2019
U6  - http://dx.doi.org/10.7717/peerj.6764
SN  - 21678359
PB  - Peer
CY  - London
ER  -