TY  - JOUR
A1  - Maggakis-Kelemen, Christina
A1  - Biselli, Manfred
A1  - Artmann, Gerhard
T1  - Determination of the elastic shear modulus of cultured human red blood cells
JF  - Biomedizinische Technik. 47 (2002), H. Suppl. 1 Pt. 1
Y1  - 2002
SN  - 0013-5585
N1  - Druckausgabe unter 63 Z 471 vorhanden
SP  - 106
EP  - 109
ER  - 
TY  - JOUR
A1  - Artmann, Gerhard
A1  - Zhou-Stache, J.
A1  - Buettner, R.
A1  - Mittermayer, C. [u.a.]
T1  - Inhibition of TNF-alpha induced cell death in HUVEC and Jurkat cells by protocatechuic acid. Zhou-Stache, J.; Buettner, R.; Artmann, Gerhard Michael; Mittermayer, C.; Bosserhoff, A. K.
JF  - Medical and Biological Engineering and Computing. 40 (2002), H. 6
Y1  - 2002
SN  - 0140-0118
SP  - 698
EP  - 703
ER  - 
TY  - JOUR
A1  - Maggakis-Kelemen, C.
A1  - Bork, M.
A1  - Kayser, Peter
A1  - Biselli, Manfred
A1  - Artmann, Gerhard
T1  - Biological and mechanical quality of red blood cells cultured from human umbilical cord blood stem cells
JF  - Medical and biological engineering and computing. 41 (2003), H. 3
Y1  - 2003
SN  - 0140-0118
SP  - 350
EP  - 356
ER  - 
TY  - JOUR
A1  - Artmann, Gerhard
A1  - Hueck, Isgard S.
A1  - Rossiter, Katharine
A1  - Schmid-Schönbein, Geert W.
T1  - Fluid Shear Attenuates Endothelial Pseudopodia Formation into the Capillary Lumen / Hueck, Isgard S. ; Rossiter, Katharine ; Artman, Gerhard M. ; Schmid-Schönbein, Geert W.
JF  - Microcirculation. 15 (2008), H. 6
Y1  - 2008
SN  - 1549-8719
SP  - 531
EP  - 542
ER  - 
TY  - BOOK
A1  - Artmann, Gerhard
T1  - Bioengineering in Cell and Tissue Research / Artmann, Gerhard M. ; Chien, Shu (Eds.)
Y1  - 2008
SN  - 978-3-540-75408-4
PB  - Springer
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Kaul, D. K.
A1  - Koshkaryev, A.
A1  - Artmann, Gerhard
A1  - Barshtein, G.
A1  - Yedgar, S.
T1  - Additive effect of red blood cell rigidity and adherence to endothelial cells in inducing vascular resistance
JF  - American Journal of Physiology : Heart and Circulation Physiology . 295 (2008), H. 4
Y1  - 2008
SN  - 1522-1539
VL  - 295
IS  - 4
SP  - H1788
EP  - H1793
ER  - 
TY  - JOUR
A1  - Becker, C.
A1  - Wallang, C.
A1  - Artmann, Gerhard
A1  - Jakse, G.
T1  - Mechanotransduction-bioreactor for tissue engineering of a ureter prosthesis
JF  - International Journal of Artificial Organs, The
Y1  - 2008
SN  - 0391-3988
N1  - Abstracts from the XXXV Congress of the European Society for Artificial Organs: 'Towards Future Biomedical Technologies' - ORAL PRESENTATIONS
VL  - 31
IS  - 7
SP  - 583
EP  - 583
ER  - 
TY  - JOUR
A1  - Eijck, Lambert van
A1  - Demmel, Franz
A1  - Artmann, Gerhard
A1  - Stadtler, Andreas Maximilian
T1  - Macromolecular dynamics in red blood cells investigated using neutron spectroscopy
JF  - Journal of the Royal Society Interface
Y1  - 2011
SN  - 1742-5689
VL  - 8
IS  - 57
SP  - 590
EP  - 600
PB  - The Royal Society
CY  - London
ER  - 
TY  - BOOK
A1  - Artmann, Gerhard
T1  - Stem cell engineering : principles and applications / Gerhard M. Artmann ... eds.
Y1  - 2011
SN  - 978-3-642-11864-7
PB  - Springer
CY  - Berlin [u.a.]
ER  - 
TY  - JOUR
A1  - Stadler, Alexander Maximilian
A1  - Garvey, Christopher J.
A1  - Embs, Jan Peter
A1  - Koza, Michael Marek
A1  - Unruh, Tobias
A1  - Artmann, Gerhard
A1  - Zaccai, Guiseppe
T1  - Picosecond dynamics in haemoglobin from different species: A quasielastic neutron scattering study
JF  - Biochimica et biophysica acta (BBA): General Subjects
Y1  - 2014
U6  - http://dx.doi.org/10.1016/j.bbagen.2014.06.007
SN  - 1872-8006 (E-Journal); 0304-4165 (Print)
VL  - 1840
IS  - 10
SP  - 2989
EP  - 2999
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - PAT
A1  - Artmann, Gerhard
A1  - Linder, Peter
A1  - Bayer, Robin
A1  - Gossmann, Matthias
T1  - Celldrum electrode arrangement for measuring mechanical stress [Patent of invention]
N2  - The invention pertains to a CellDrum electrode arrangement for measuring mechanical stress, comprising a mechanical holder (1 ) and a non-conductive membrane (4), whereby the membrane (4) is at least partially fixed at its circumference to the mechanical holder (1), keeping it in place when the membrane (4) may bend due to forces acting on the membrane (4), the mechanical holder (1) and the membrane (4) forming a container, whereby the membrane (1) within the container comprises an cell- membrane compound layer or biological material (3) adhered to the deformable membrane 4 which in response to stimulation by an agent may exert mechanical stress to the membrane (4) such that the membrane bending stage changes whereby the container may be filled with an electrolyte, whereby an electric contact (2) is arranged allowing to contact said electrolyte when filled into to the container, whereby within a predefined geometry to the fixing of the membrane (4) an electrode (7) is arranged, whereby the electrode (7) is electrically insulated with respect to the electric contact (2) as well as said electrolyte, whereby mechanical stress due to an agent may be measured as a change in capacitance.
Y1  - 2017
N1  - Patent auch unter EP3403090, CN109477828, US2019033245 und LU92948 veröffentlicht.
PB  - WIPO
CY  - Geneva
ER  - 
TY  - CHAP
A1  - Azat, Seitkhan
A1  - Kerimkulova, Almagul R.
A1  - Mansurov, Zulkhair A.
A1  - Adekenov, Sergazy
A1  - Artmann, Gerhard
T1  - The Use of Fusicoccin as Anticancer Compound
T2  - Carbon Nanomaterials in Biomedicine and the Environment
N2  - The problem of creation and use of sorption materials is of current interest for the practice of the modern medicine and agriculture. Practical importance is production of a biostimulant using a carbon sorbent for a significant increase in productivity, which is very relevant for the regions of Kazakhstan. It is known that a plant phytohormone—fusicoccin—in nanogram concentrations transforms cancer cells to the state of apoptosis. In this regard, there is a scientific practical interest in the development of a highly efficient method for producing fusicoccin from extract of germinated wheat seeds. According to the results of computer modeling, cleaning composite components of fusicoccin using microporous carbon adsorbents not suitable as the size of the molecule of fusicoccin more than micropores and the optimum pore size for purification of constituents of fusicoccin was determined by computer simulation.
Y1  - 2020
SN  - 978-0-429-42864-7
U6  - http://dx.doi.org/10.1201/9780429428647-8
SP  - 149
EP  - 172
PB  - Jenny Stanford Publishing
CY  - New York
ER  - 
TY  - CHAP
A1  - Staat, Manfred
A1  - Tran, Thanh Ngoc
A1  - Pham, Phu Tinh
T1  - Limit and shakedown reliability analysis by nonlinear programming
N2  - 7th International Conference on Reliability of Materials and Structures (RELMAS 2008). June 17 - 20, 2008 ; Saint Petersburg, Russia. pp 354-358. Reprint with corrections in red Introduction Analysis of advanced structures working under extreme heavy loading such as nuclear power plants and piping system should take into account the randomness of loading, geometrical and material parameters. The existing reliability are restricted mostly to the elastic working regime, e.g. allowable local stresses. Development of the limit and shakedown reliability-based analysis and design methods, exploiting potential of the shakedown working regime, is highly needed. In this paper the application of a new algorithm of probabilistic limit and shakedown analysis for shell structures is presented, in which the loading and strength of the material as well as the thickness of the shell are considered as random variables. The reliability analysis problems may be efficiently solved by using a system combining the available FE codes, a deterministic limit and shakedown analysis, and the First and Second Order Reliability Methods (FORM/SORM). Non-linear sensitivity analyses are obtained directly from the solution of the deterministic problem without extra computational costs.
KW  - Finite-Elemente-Methode
KW  - Limit analysis
KW  - Shakedown analysis
Y1  - 2008
ER  - 
TY  - CHAP
A1  - Tran, Thanh Ngoc
A1  - Pham, Phu Tinh
A1  - Staat, Manfred
T1  - Reliability analysis of shells based on direct plasticity methods
N2  - Abstracts der CD-Rom Proceedings of the 8th World Congress on Computational Mechanics (WCCM8) and 5th Congress on Computational Methods in Applied Sciences and Engineering (ECCOMAS 2008) 30.06. - 04.07.2008 Venedig, Italien. 2 Seiten Zusammenfassung der Autoren mit graph. Darst. und Literaturverzeichnis
N2  - Abstracts of the Proceedings of the 8th World Congress on Computational Mechanics (WCCM8) and 5th Congress on Computational Methods in Applied Sciences and Engineering (ECCOMAS 2008) June 30th - July, 4th 2008, Venice, Italy. 2 pages with abstracts of the authors, Ill. and references.
KW  - Finite-Elemente-Methode
KW  - Limit analysis
KW  - Shakedown analysis
KW  - First-order reliability method
KW  - second-order reliability method
KW  - Sensitivity
Y1  - 2008
ER  - 
TY  - CHAP
A1  - Tran, Thanh Ngoc
A1  - Novacek, V.
A1  - Tolba, R.
A1  - Klinge, U.
A1  - Turquier, F.
A1  - Staat, Manfred
T1  - Experimental and Computational approach to study colorectal anastomosis. ISB2011, Proceedings of the XXIII Congress of the International Society of Biomechanics, Brussels, Belgium, July 3-7, 2011
N2  - Summary: This paper presents a methodology to study and understand the mechanics of stapled anastomotic behaviors by combining empirical experimentation and finite element analysis. Performance of stapled anastomosis is studied in terms of leakage and numerical results which are compared to in vitro experiments performed on fresh porcine tissue. Results suggest that leaks occur between the tissue and staple legs penetrating through the tissue.
KW  - Anastomose
KW  - Finite-Elemente-Methode
KW  - Biomechanik
KW  - Anastomosis
KW  - Finite element method
KW  - Biomechanics
Y1  - 2011
ER  - 
TY  - JOUR
A1  - Staat, Manfred
T1  - Some Achievements of the European Project LISA for FEM Based Limit and Shakedown Analysis
JF  - Computational mechanics : developments and applications, 2002 : presented at the 2002 ASME Pressure Vessels and Piping Conference, Vancouver, British Columbia, Canada, August 5 - 9. / Badie, N. [ed]
Y1  - 2002
SN  - 0791846520
N1  - Serie PVP ; vol. 441.
SP  - 177
EP  - 185
PB  - American Society of Mechanical Engineers
CY  - New York
ER  - 
TY  - JOUR
A1  - Staat, Manfred
A1  - Heitzer, M.
A1  - Lang, H.
A1  - Wirtz, K.
T1  - Direct Finite Element Route for Design-by-Analysis of Pressure Components
JF  - International Journal of Pressure Vessels and Piping. 82 (2005), H. 1
Y1  - 2005
SN  - 0308-0161
SP  - 61
EP  - 67
ER  - 
TY  - JOUR
A1  - Staat, Manfred
T1  - Plastic collapse analysis of longitudinally flawed pipes and vessels
JF  - Nuclear Engineering and Design. 234 (2004), H. 1-3
Y1  - 2004
SN  - 0029-5493
SP  - 25
EP  - 43
ER  - 
TY  - JOUR
A1  - Staat, Manfred
A1  - Heitzer, M.
A1  - Reiners, H.
A1  - Schubert, F.
T1  - Shakedown and ratchetting under tension–torsion loadings: analysis and experiments
JF  - Nuclear Engineering and Design. 225 (2003), H. 1
Y1  - 2003
SN  - 0029-5493
SP  - 11
EP  - 26
ER  - 
TY  - JOUR
A1  - Staat, Manfred
A1  - Schwartz, M.
A1  - Lang, H.
A1  - Wirtz, K.
A1  - Heitzer, M.
T1  - Design by Analysis of Pressure Components by non-linear Optimization
JF  - The 10th International Conference on Pressure Vessel Technology, July 7-10, 2003, Vienna, Austria, Proceedings ICPVT-10 / Zeman, J. L. [ed]
Y1  - 2003
SN  - 3950152814
SP  - 59
EP  - 65
PB  - ÖGS, Österreichische Gesellschaft für Schweißtechnik
CY  - Wien
ER  - 
TY  - JOUR
A1  - Staat, Manfred
A1  - Heitzer, M.
T1  - Limit and Shakedown Analysis with Uncertain Data
JF  - Stochastic optimization techniques : numerical methods and technical applications / Marti, K. [ed]
Y1  - 2002
SN  - 3-540-42889-5
SP  - 241
EP  - 254
PB  - Springer
CY  - Heidelberg
ER  - 
TY  - JOUR
A1  - Staat, Manfred
A1  - Heitzer, M.
T1  - Probabilistic limit and shakedown problems
JF  - Numerical Methods for Limit and Shakedown Analysis. Deterministic and Probabilistic Approach. NIC Series Vol. 15 / Ed. by Staat, M; Heitzer, M.
Y1  - 2003
SN  - 3-00-010001-6
SP  - 217
EP  - 268
PB  - John von Neumann Institute for Computing (NIC)
CY  - Jülich
ER  - 
TY  - CHAP
A1  - Staat, Manfred
A1  - Heitzer, M.
T1  - Basis reduction technique for limit and shakedown problems
T2  - Numerical Methods for Limit and Shakedown Analysis. Deterministic and Probabilistic Approach. NIC Series Vol. 15 / Ed. by Staat, M.; Heitzer, M.
Y1  - 2003
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:0001-2018112115
SN  - 3-00-010001-6
SP  - 1
EP  - 55
PB  - John von Neumann Institute for Computing (NIC)
CY  - Jülich
ER  - 
TY  - JOUR
A1  - Staat, Manfred
T1  - Local and global collapse pressure of longitudinally flawed pipes and cylindrical vessels
JF  - International Journal of Pressure Vessels and Piping. 82 (2005), H. 3
Y1  - 2005
SN  - 0308-0161
SP  - 217
EP  - 225
ER  - 
TY  - JOUR
A1  - Staat, Manfred
A1  - Vu, Duc-Khoi
T1  - An Algorithm for Shakedown Analysis for Materials with Temperature Dependent Yield Stress
JF  - Proceedings in Applied Mathematics and Mechanics (PAMM). 4 (2004), H. 1
Y1  - 2004
SN  - 1617-7061
SP  - 231
EP  - 233
ER  - 
TY  - JOUR
A1  - Staat, Manfred
A1  - Vu, Khoi Duc
T1  - Limit loads of circumferentially flawed pipes and cylindrical vessels under internal pressure
JF  - International Journal of Pressure Vessels and Piping. 83 (2006), H. 3
Y1  - 2006
SN  - 0308-0161
SP  - 188
EP  - 196
ER  - 
TY  - JOUR
A1  - Staat, Manfred
A1  - Vu, Duc-Khoi
T1  - Limit analysis of flaws in pressurized pipes and cylindrical vessels. Part I: Axial defects
JF  - Engineering Fracture Mechanics. 74 (2007), H. 3
Y1  - 2007
SN  - 0013-7944
SP  - 431
EP  - 450
ER  - 
TY  - JOUR
A1  - Vu, Duc Khoi
A1  - Staat, Manfred
A1  - Tran, Ich Thinh
T1  - Analysis of pressure equipment by application of the primal-dual theory of shakedown
JF  - Communications in Numerical Methods in Engineering. 23 (2007), H. 3
Y1  - 2007
SN  - 1069-8299
SP  - 213
EP  - 225
ER  - 
TY  - JOUR
A1  - Vu, Duc Khoi
A1  - Staat, Manfred
T1  - Shakedown analysis of structures made of materials with temperature-dependent yield stress
JF  - International Journal of Solids and Structures. 44 (2007), H. 13
Y1  - 2007
SN  - 0020-7683
SP  - 4524
EP  - 4540
ER  - 
TY  - JOUR
A1  - Vant, Christianne
A1  - Staat, Manfred
A1  - Baroud, Gamal
T1  - Percutaneous Vertebroplasty: A Review of Two Intraoperative Complications
JF  - Bioengineering in Cell and Tissue Research / Artmann, Gerhard M. ; Chien, Shu (Eds.)
Y1  - 2008
SN  - 978-3-540-75408-4
SP  - 527
EP  - 539
PB  - Springer
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Tran, Thanh Ngoc
A1  - Kreißig, R.
A1  - Vu, Duc Khoi
A1  - Staat, Manfred
T1  - Upper bound limit and shakedown analysis of shells using the exact Ilyushin yield surface
JF  - Computer & Structures. 86 (2008)
Y1  - 2008
SN  - 0045-7949
SP  - 1683
EP  - 1695
ER  - 
TY  - JOUR
A1  - Staat, Manfred
A1  - Tran, Thanh Ngoc
A1  - Kreißig, R.
T1  - Load bearing capacity of thin shell structures made of elastoplastic material by direct methods
JF  - Technische Mechanik. 28 (2008), H. 3-4
Y1  - 2008
SP  - 299
EP  - 309
ER  - 
TY  - JOUR
A1  - Tran, Thanh Ngoc
A1  - Kreißig, R.
A1  - Staat, Manfred
T1  - Probabilistic limit and shakedown analysis of thin plates and shells
JF  - Structural safety. 31 (2009), H. 1
Y1  - 2009
SN  - 0167-4730
SP  - 1
EP  - 18
PB  - -
ER  - 
TY  - JOUR
A1  - Tran, Thanh Ngoc
A1  - Pham, Phu Tinh
A1  - Vu, D. K.
A1  - Staat, Manfred
T1  - Reliability Analysis of Inelastic Shell Structures Under Variable Loads
JF  - Limit States of Materials and Structures : Direct Methods / Hrsg. Dieter Weichert; Hrsg. Alan Ponter
Y1  - 2009
SN  - 978-1-4020-9633-4
SP  - 135
EP  - 156
PB  - Springer Netherland
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Ullrich, Sebastian
A1  - Grottke, Oliver
A1  - Rossaint, Rolf
A1  - Staat, Manfred
A1  - Deserno, Thomas M.
A1  - Kuhlen, Torsten
T1  - Virtual Needle Simulation with Haptics for Regional Anaesthesia
Y1  - 2010
N1  - IEEE Virtual Reality 2010, Workshop on Medical Virtual Environments, Waltham, MA, USA, March 21, 2010
SP  - 1
EP  - 3
ER  - 
TY  - JOUR
A1  - Nguyen, N.-H.
A1  - Raatschen, Hans-Jürgen
A1  - Staat, Manfred
T1  - A hyperelastic model of biological tissue materials in tubular organs
Y1  - 2010
N1  - ECCM 2010, IV European Conference on Computational Mechanics, Paris, France, May 16-21, 2010.
SP  - 1
EP  - 12
ER  - 
TY  - JOUR
A1  - Pham, Phu Tinh
A1  - Vu, Khoi Duc
A1  - Tran, Thanh Ngoc
A1  - Staat, Manfred
T1  - A primal-dual algorithm for shakedown analysis of elastic-plastic bounded linearly kinematic hardening bodies
Y1  - 2010
N1  - ECCM 2010, IV European Conference on Computational Mechanics, Paris, France, May 16-21, 2010.
SP  - 1
EP  - 7
ER  - 
TY  - JOUR
A1  - Tran, Thanh Ngoc
A1  - Staat, Manfred
T1  - Shakedown analysis of two dimensional structures by an edge-based smoothed finite element method
Y1  - 2010
N1  - ECCM 2010, IV European Conference on Computational Mechanics, Paris, France, May 16-21, 2010.
SP  - 1
EP  - 7
ER  - 
TY  - JOUR
A1  - Grottke, O.
A1  - Braunschweig, T.
A1  - Philippen, B.
A1  - Gatzweiler, Karl-Heinz
A1  - Gronloh, N.
A1  - Staat, Manfred
A1  - Rossaint, R.
A1  - Tolba, R.
T1  - A New Model for Blunt Liver Injuries in the Swine
JF  - European Surgical Research. 44 (2010), H. 2
Y1  - 2010
SN  - 1421-9921
SP  - 65
EP  - 73
ER  - 
TY  - JOUR
A1  - Staat, Manfred
A1  - Vu, Duc Khoi
T1  - Limit analysis of flaws in pressurized pipes and cylindrical vessels Part II: Circumferential defects
JF  - Engineering Fracture Mechanics ; 97(2013), H. 1
N2  - Upper and lower bound theorems of limit analyses have been presented in part I of the paper. Part II starts with the finite element discretization of these theorems and demonstrates how both can be combined in a primal–dual optimization problem. This recently proposed numerical method is used to guide the development of a new class of closed-form limit loads for circumferential defects, which show that only large defects contribute to plastic collapse with a rapid loss of strength with increasing crack sizes. The formulae are compared with primal–dual FEM limit analyses and with burst tests. Even closer predictions are obtained with iterative limit load solutions for the von Mises yield function and for the Tresca yield function. Pressure loading of the faces of interior cracks in thick pipes reduces the collapse load of circumferential defects more than for axial flaws. Axial defects have been treated in part I of the paper.
Y1  - 2012
U6  - http://dx.doi.org/10.1016/j.engfracmech.2012.05.017
SN  - 0013-7944
VL  - 97
SP  - 314
EP  - 333
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Staat, Manfred
A1  - Trenz, Eva
A1  - Lohmann, Philipp
A1  - Frotscher, Ralf
A1  - Klinge, Uwe
A1  - Tabaza, Ruth
A1  - Kirschner-Hermanns, Ruth
T1  - New measurements to compare soft tissue anchoring systems in pelvic floor surgery
JF  - Journal of Biomedical Materials Research Part B: Applied Biomaterials
N2  - Suburethral slings as well as different meshes are widely used treating stress urinary incontinence and prolaps in women. With the development of MiniSlings and special meshes using less alloplastic material anchorage systems become more important to keep devices in place and to put some tension especially on the MiniSlings. To date, there are many different systems of MiniSlings of different companies on the market which differ in the structure of the used meshes and anchors. A new objective measurement method to compare different properties of MiniSling systems (mesh and anchor) is presented in this article. Ballistic gelatine acts as soft tissue surrogate. Significant differences in parameters like pull-out strength of anchors or shrinkage of meshes under loading conditions have been determined. The form and size of the anchors as well as the structural stability of the meshes are decisive for a proper integration. The tested anchorings sytems showed markedly different mechanical function at their respective load bearing capacity. As the stable fixation of the device in tissue is a prerequisite for a permanet reinforcement, the proposed test system permits further optimisation of anchor and mesh devices to improve the success of the surgical treatment
Y1  - 2012
U6  - http://dx.doi.org/10.1002/jbm.b.32654
SN  - 1552-4981
VL  - 100B
IS  - 4
SP  - 924
EP  - 933
PB  - Wiley
CY  - Hoboken, NJ
ER  - 
TY  - JOUR
A1  - Novacek, V.
A1  - Tran, Thanh Ngoc
A1  - Klinge, U.
A1  - Tolba, R. H.
A1  - Staat, Manfred
A1  - Bronson, D. G.
A1  - Miesse, A. M.
A1  - Whiffen, J.
A1  - Turquier, F.
T1  - Finite element modelling of stapled colorectal end-to-end anastomosis : Advantages of variable height stapler design
JF  - Journal of Biomechanics
N2  - The impact of surgical staplers on tissues has been studied mostly in an empirical manner. In this paper, finite element method was used to clarify the mechanics of tissue stapling and associated phenomena. Various stapling modalities and several designs of circular staplers were investigated to evaluate the impact of the device on tissues and mechanical performance of the end-to-end colorectal anastomosis. Numerical simulations demonstrated that a single row of staples is not adequate to resist leakage due to non-linear buckling and opening of the tissue layers between two adjacent staples. Compared to the single staple row configuration, significant increase in stress experienced by the tissue at the inner staple rows was observed in two and three rows designs. On the other hand, adding second and/or third staple row had no effect on strain in the tissue inside the staples. Variable height design with higher staples in outer rows significantly reduced the stresses and strains in outer rows when compared to the same configuration with flat cartridge.
KW  - Variable height stapler design
KW  - Anastomotic leakage
KW  - Finite element modelling
KW  - End-to-end colorectal anastomosis
KW  - Surgical staplers
Y1  - 2012
U6  - http://dx.doi.org/10.1016/j.jbiomech.2012.07.021
SN  - 1873-2380
VL  - 45
IS  - 115
SP  - 2693
EP  - 2697
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Nguyen, Nhu Huynh
A1  - Duong, Minh Tuan
A1  - Tran, Thanh Ngoc
A1  - Pham, Phu Tinh
A1  - Grottke, O.
A1  - Tolba, R.
A1  - Staat, Manfred
T1  - Influence of a freeze–thaw cycle on the stress–stretch curves of tissues of porcine abdominal organs
JF  - Journal of Biomechanics
N2  - The paper investigates both fresh porcine spleen and liver and the possible decomposition of these organs under a freeze–thaw cycle. The effect of tissue preservation condition is an important factor which should be taken into account for protracted biomechanical tests. In this work, tension tests were conducted for a large number of tissue specimens from twenty pigs divided into two groups of 10. Concretely, the first group was tested in fresh state; the other one was tested after a freeze-thaw cycle which simulates the conservation conditions before biomechanical experiments. A modified Fung model for isotropic behavior was adopted for the curve fitting of each kind of tissues. Experimental results show strong effects of the realistic freeze–thaw cycle on the capsule of elastin-rich spleen but negligible effects on the liver which virtually contains no elastin. This different behavior could be explained by the autolysis of elastin by elastolytic enzymes during the warmer period after thawing. Realistic biomechanical properties of elastin-rich organs can only be expected if really fresh tissue is tested. The observations are supported by tests of intestines.
KW  - Autolysis
KW  - Decomposition
KW  - Freeze–thaw process
KW  - Spleen
KW  - Liver
Y1  - 2012
U6  - http://dx.doi.org/10.1016/j.jbiomech.2012.07.008
SN  - 1873-2380
VL  - 45
IS  - 14
SP  - 2382
EP  - 2386
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Pham, Phu Tinh
A1  - Staat, Manfred
T1  - An Upper Bound Algorithm for Limit and Shakedown Analysis of Bounded Linearly Kinematic Hardening Structures
JF  - Limit State of Materials and Structures : Direct Methods 2. Saxcé, Géry de (Hrsg.)
Y1  - 2013
SN  - 978-94-007-5424-9
SP  - 71
EP  - 87
PB  - Springer
CY  - Dordrecht
ER  - 
TY  - JOUR
A1  - Tran, Thanh Ngoc
A1  - Staat, Manfred
T1  - An Edge-Based Smoothed Finite Element Method for Primal-Dual Shakedown Analysis of Structures Under Uncertainties
JF  - Limit State of Materials and Structures : Direct Methods 2. Saxcé, Géry de (Hrsg.)
Y1  - 2013
SN  - 978-94-007-5424-9
SP  - 89
EP  - 102
PB  - Springer
CY  - Dordrecht
ER  - 
TY  - JOUR
A1  - Hasan, Istabrak
A1  - Keil, Ludger
A1  - Staat, Manfred
A1  - Wahl, Gerhard
A1  - Bourauel, Christoph
T1  - Determination of the frictional coefficient of the implant-antler interface : experimental approach
JF  - Biomedical Engineering / Biomedizinische Technik
N2  - The similar bone structure of reindeer antler to human bone permits studying the osseointegration of dental implants in the jawbone. As the friction is one of the major factors that have a significant influence on the initial stability of immediately loaded dental implants, it is essential to define the frictional coefficient of the implant-antler interface. In this study, the kinetic frictional forces at the implant-antler interface were measured experimentally using an optomechanical setup and a stepping motor controller under different axial loads and sliding velocities. The corresponding mean values of the static and kinetic frictional coefficients were within the range of 0.5–0.7 and 0.3–0.5, respectively. An increase in the frictional forces with increasing applied axial loads was registered. The measurements showed an evidence of a decrease in the magnitude of the frictional coefficient with increasing sliding velocity. The results of this study provide a considerable assessment to clarify the suitable frictional coefficient to be used in the finite element contact analysis of antler specimens.
Y1  - 2012
SN  - 1862-278X
VL  - 57
IS  - 5
SP  - 359
EP  - 363
PB  - De Gruyter
CY  - Berlin
ER  - 
TY  - CHAP
A1  - Nix, Yvonne
A1  - Frotscher, Ralf
A1  - Staat, Manfred
ED  - Eberhardsteiner, J.
T1  - Implementation of the edge-based smoothed extended finite element method
T2  - Proceedings 6th European Congress on Computational Methods in Applied Sciences and Engineering (ECCOMAS 2012) Vienna, Austria, September 10-14, 2012
Y1  - 2012
ER  - 
TY  - CHAP
A1  - Frotscher, Ralf
A1  - Raatschen, Hans-Jürgen
A1  - Staat, Manfred
ED  - Eberhardsteiner, J.
T1  - Application of an edge-based smoothed finite element method on geometrically non-linear plates of non-linear material
T2  - Proceedings European Congress on Computational Methods in Applied Sciences and Engineering (ECCOMAS 2012)
Y1  - 2012
N1  - 6th European Congress on Computational Methods in Applied Sciences and Engineering (ECCOMAS 2012) Vienna, Austria, September 10-14, 2012
ER  - 
TY  - CHAP
A1  - Duong, Minh Tuan
A1  - Nguyen, Nhu Huynh
A1  - Staat, Manfred
ED  - Eberhardsteiner, J.
T1  - Numerical stability enhancement of modeling hyperelastic materials
T2  - Proceedings European Congress on Computational Methods in Applied Sciences and Engineering (ECCOMAS 2012)
Y1  - 2012
N1  - 6th European Congress on Computational Methods in Applied Sciences and Engineering (ECCOMAS 2012) Vienna, Austria, September 10-14, 2012
ER  - 
TY  - CHAP
A1  - Tran, Thanh Ngoc
A1  - Staat, Manfred
ED  - Eberhardsteiner, J.
T1  - A primal-dual shakedown analysis of 3D structures using the face-based smoothed finite element method
T2  - Proceedings European Congress on Computational Methods in Applied Sciences and Engineering (ECCOMAS 2012)
Y1  - 2012
N1  - 6th European Congress on Computational Methods in Applied Sciences and Engineering (ECCOMAS 2012) Vienna, Austria, September 10-14, 2012
ER  -